239 Matching Annotations
  1. Apr 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 06 Apr 2021
      InVivoPlus anti-mouse PD-1 (CD279)

      DOI: 10.1016/j.immuni.2021.02.020

      Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)

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    sciencedirect.com/science/article/pii/S1074761321000868
  3. Mar 2021
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor
    1
    1. scibot 17 Mar 2021
      RRID:AB_10949053

      DOI: 10.1126/scisignal.aau4518

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    ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
  5. www.sciencedirect.com www.sciencedirect.com
    Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer
    1
    1. scibot 08 Mar 2021
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2020.12.001

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    sciencedirect.com/science/article/pii/S1535610820306085
  6. Feb 2021
  7. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
    1
    1. scibot 26 Feb 2021
      RRID:AB_10949053

      DOI: 10.1172/jci.insight.134386

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    insight.jci.org/articles/view/134386
  8. Jan 2021
  9. www.sciencedirect.com www.sciencedirect.com
    Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma
    1
    1. scibot 21 Jan 2021
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2020.108620

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    sciencedirect.com/science/article/pii/S2211124720316090
  10. Sep 2020
  11. www.sciencedirect.com www.sciencedirect.com
    Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance
    1
    1. scibot 23 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2019.12.003

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    sciencedirect.com/science/article/pii/S1535610819305732
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    Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer
    1
    1. scibot 23 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2020.02.008

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    sciencedirect.com/science/article/pii/S1535610820300970
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    FOXD3 Regulates VISTA Expression in Melanoma
    1
    1. scibot 23 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.12.036

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    sciencedirect.com/science/article/pii/S2211124719316936
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    CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity
    1
    1. scibot 14 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.immuni.2020.03.001

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    sciencedirect.com/science/article/pii/S1074761320300893
  15. insight.jci.org insight.jci.org
    Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration
    1
    1. scibot 10 Sep 2020
      RRID: AB_10949053

      DOI: 10.1172/jci.insight.134386

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    insight.jci.org/articles/view/134386
  16. www.sciencedirect.com www.sciencedirect.com
    Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy
    1
    1. scibot 10 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.12.013

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    sciencedirect.com/science/article/pii/S2211124719316626
  17. www.sciencedirect.com www.sciencedirect.com
    ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis
    1
    1. scibot 07 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2020.02.006

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    sciencedirect.com/science/article/pii/S1535610820300957
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    Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma
    1
    1. scibot 06 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2020.03.016

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    sciencedirect.com/science/article/pii/S1535610820301562
  19. www.sciencedirect.com www.sciencedirect.com
    Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP
    1
    1. scibot 05 Sep 2020
      RRID:AB_10949053

      DOI: 10.1016/j.immuni.2020.01.014

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    sciencedirect.com/science/article/pii/S107476132030042X
  20. Jan 2020
  21. www.sciencedirect.com www.sciencedirect.com
    Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2019.10.008

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    sciencedirect.com/science/article/pii/S1535610819304829
  22. www.sciencedirect.com www.sciencedirect.com
    B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.cell.2019.10.028

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    sciencedirect.com/science/article/pii/S009286741931178X
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.03.066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6719696/
  24. www.sciencedirect.com www.sciencedirect.com
    Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity
    1
    1. scibot 13 Jan 2020
      RRID:RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.07.044

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    sciencedirect.com/science/article/pii/S2211124719309416
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    PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.immuni.2019.11.003

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    sciencedirect.com/science/article/pii/S1074761319304613
  26. www.sciencedirect.com www.sciencedirect.com
    Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.cell.2019.07.019

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      Curator: @ethanbadger

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    sciencedirect.com/science/article/pii/S0092867419307846
  27. www.sciencedirect.com www.sciencedirect.com
    The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2019.06.009

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    sciencedirect.com/science/article/pii/S1535610819303009
  28. www.sciencedirect.com www.sciencedirect.com
    Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.cell.2019.10.029

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    sciencedirect.com/science/article/pii/S0092867419311791
  29. www.sciencedirect.com www.sciencedirect.com
    Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2019.10.001

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    sciencedirect.com/science/article/pii/S1535610819304398
  30. www.sciencedirect.com www.sciencedirect.com
    Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.05.020

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    sciencedirect.com/science/article/pii/S221112471930631X
  31. www.cell.com www.cell.com
    Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.celrep.2019.04.091

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    cell.com/cell-reports/fulltext/S2211-1247(19)30571-6
  32. www.sciencedirect.com www.sciencedirect.com
    Untitled document
    1
    1. scibot 13 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.immuni.2018.12.021

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    sciencedirect.com/science/article/pii/S1074761318305697
  33. www.sciencedirect.com www.sciencedirect.com
    Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation
    1
    1. scibot 12 Jan 2020
      RRID:AB_10949053

      DOI: 10.1016/j.ccell.2019.04.003

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    sciencedirect.com/science/article/pii/S1535610819301989
  34. Nov 2018
  35. www.sciencedirect.com www.sciencedirect.com
    Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures
    1
    1. scibot 05 Nov 2018
      RRID:AB_10949053

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    sciencedirect.com/science/article/pii/S0092867418309139
  36. www.sciencedirect.com www.sciencedirect.com
    IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S2405471218302382
  37. www.sciencedirect.com www.sciencedirect.com
    Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1074761317304235
  38. www.sciencedirect.com www.sciencedirect.com
    Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S153561081830223X
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    Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1550413118301177
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    Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S1074761317305332
  41. www.sciencedirect.com www.sciencedirect.com
    TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer
    1
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    sciencedirect.com/science/article/pii/S1535610817305238
  42. www.sciencedirect.com www.sciencedirect.com
    Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment
    1
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    sciencedirect.com/science/article/pii/S1535610817304713
  43. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer
    1
    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867417312448
  44. Nov 2017
  45. www.sciencedirect.com www.sciencedirect.com
    Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade
    1
    1. scibot 08 Nov 2017
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      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1535610817302982
  46. www.sciencedirect.com www.sciencedirect.com
    Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
    1
    1. scibot 08 Nov 2017
      Anti-PD-1 (clone RMP1-14)BioXcellCat# BE0146

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0092867417308310
  47. www.sciencedirect.com www.sciencedirect.com
    Systemic Immunity Is Required for Effective Cancer Immunotherapy
    1
    1. scibot 08 Nov 2017
      Cat# BE0146

      Curator: @Zeljana_Babic

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      RRID:AB_10949053 RRIDCUR:Missing
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    sciencedirect.com/science/article/pii/S009286741631738X