303 Matching Annotations
  1. May 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Systematic Functional Analysis of SARS-CoV-2 Proteins Uncovers Viral Innate Immune Antagonists and Remaining Vulnerabilities
    1
    1. scibot 11 May 2021
      RRID:AB_10956166

      DOI: 10.1016/j.celrep.2021.109126

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    sciencedirect.com/science/article/pii/S2211124721004654
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    TSC1 binding to lysosomal PIPs is required for TSC complex translocation and mTORC1 regulation
    1
    1. scibot 11 May 2021
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      DOI: 10.1016/j.molcel.2021.04.019

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    sciencedirect.com/science/article/pii/S1097276521003245
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    Proteasome-Bound UCH37/UCHL5 Debranches Ubiquitin Chains to Promote Degradation
    1
    1. scibot 07 May 2021
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      DOI: 10.1016/j.molcel.2020.10.017

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    sciencedirect.com/science/article/pii/S1097276520307243
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    PIWI proteomics identifies Atari and Pasilla as piRNA biogenesis factors in Aedes mosquitoes
    1
    1. scibot 05 May 2021
      RRID:AB_10956166

      DOI: 10.1016/j.celrep.2021.109073

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    sciencedirect.com/science/article/pii/S2211124721004046
  6. Apr 2021
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    Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability
    1
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      DOI: 10.1016/j.cmet.2020.12.002

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    sciencedirect.com/science/article/pii/S1550413120306574
  8. www.cell.com www.cell.com
    IL6/STAT3 Signaling Hijacks Estrogen Receptor α Enhancers to Drive Breast Cancer Metastasis
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      DOI: 10.1016/j.ccell.2020.06.007

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    cell.com/cancer-cell/fulltext/S1535-6108(20)30311-1
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    Mitochondrial biogenesis in developing astrocytes regulates astrocyte maturation and synapse formation
    1
    1. scibot 15 Apr 2021
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      DOI: 10.1016/j.celrep.2021.108952

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    sciencedirect.com/science/article/pii/S2211124721002667
  10. www.cell.com www.cell.com
    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
    1
    1. scibot 14 Apr 2021
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      DOI: 10.1016/j.molcel.2021.02.033

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  11. www.sciencedirect.com www.sciencedirect.com
    Argonaute-CLIP delineates versatile, functional RNAi networks in Aedes aegypti, a major vector of human viruses
    1
    1. scibot 07 Apr 2021
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      DOI: 10.1016/j.chom.2021.03.004

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    sciencedirect.com/science/article/pii/S1931312821001323
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    Integrated genomic analysis reveals key features of long undecoded transcript isoform-based gene repression
    1
    1. scibot 07 Apr 2021
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      DOI: 10.1016/j.molcel.2021.03.013

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    sciencedirect.com/science/article/pii/S1097276521001817
  13. www.sciencedirect.com www.sciencedirect.com
    Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer
    1
    1. scibot 06 Apr 2021
      IRDye 680RD Goat anti-Rabbit IgG

      DOI: 10.1016/j.immuni.2021.02.020

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    sciencedirect.com/science/article/pii/S1074761321000868
  14. Mar 2021
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    https://biorxiv.org/cgi/content/10.1101/2021.02.23.432450
    1
    1. scibot 10 Mar 2021
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      DOI: 10.1101/2021.02.23.432450

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    ncbi.nlm.nih.gov/pmc/articles/PMC7924263/
  16. Feb 2021
  17. www.paijournal.com www.paijournal.com
    Passive Immunity to Vibrio cholerae O1 Afforded by a Human Monoclonal IgA1 Antibody Expressed in Milk
    1
    1. scibot 25 Feb 2021
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      DOI: 370

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    paijournal.com/index.php/paijournal/article/view/370/253
  18. link.springer.com link.springer.com
    Changes in mitochondrial morphology modulate LPS-induced loss of calcium homeostasis in BV-2 microglial cells
    1
    1. scibot 24 Feb 2021
      anti-Rabbit

      DOI: 10.1007/s10863-021-09878-4

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    link.springer.com/article/10.1007/s10863-021-09878-4
  19. www.cell.com www.cell.com
    Plasma Membrane Furrows Control Plasticity of ER-PM Contacts
    1
    1. scibot 24 Feb 2021
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      DOI: 10.1016/j.celrep.2019.12.098

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    cell.com/cell-reports/abstract/S2211-1247(19)31763-2
  20. www.frontiersin.org www.frontiersin.org
    The Interplay Between Beta-Amyloid 1–42 (Aβ1–42)-Induced Hippocampal Inflammatory Response, p-tau, Vascular Pathology, and Their Synergistic Contributions to Neuronal Death and Behavioral Deficits
    1
    1. scibot 24 Feb 2021
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      DOI: 10.3389/fnmol.2020.552073

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    frontiersin.org/article/10.3389/fnmol.2020.552073/full
  21. Jan 2021
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic genetic variation revealed in diverse Hsp104 homologs
    1
    1. scibot 08 Jan 2021
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      DOI: 10.7554/eLife.57457

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    ncbi.nlm.nih.gov/pmc/articles/PMC7785292/
  23. Dec 2020
  24. www.sciencedirect.com www.sciencedirect.com
    TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A
    1
    1. scibot 23 Dec 2020
      RRID:AB_10956166

      DOI: 10.1016/j.celrep.2020.108543

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    sciencedirect.com/science/article/pii/S2211124720315321
  25. www.sciencedirect.com www.sciencedirect.com
    Opposite Surfaces of the Cdc15 F-BAR Domain Create a Membrane Platform That Coordinates Cytoskeletal and Signaling Components for Cytokinesis
    1
    1. scibot 23 Dec 2020
      RRID:AB_10956166

      DOI: 10.1016/j.celrep.2020.108526

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    sciencedirect.com/science/article/pii/S2211124720315151
  26. www.cell.com www.cell.com
    APP Family Regulates Neuronal Excitability and Synaptic Plasticity but Not Neuronal Survival
    1
    1. scibot 19 Dec 2020
      RRID:AB_10956166

      DOI: 10.1016/j.neuron.2020.08.011

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    cell.com/neuron/abstract/S0896-6273(20)30642-5
  27. www.sciencedirect.com www.sciencedirect.com
    Mechanisms of EMRE-Dependent MCU Opening in the Mitochondrial Calcium Uniporter Complex
    1
    1. scibot 13 Dec 2020
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      DOI: 10.1016/j.celrep.2020.108486

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    sciencedirect.com/science/article/pii/S2211124720314753
  28. link.springer.com link.springer.com
    Cell-autonomous role of Presenilin in age-dependent survival of cortical interneurons
    1
    1. scibot 11 Dec 2020
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      DOI: 10.1186/s13024-020-00419-y

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    link.springer.com/article/10.1186/s13024-020-00419-y
  29. Nov 2020
  30. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Loss of Muscle Carnitine Palmitoyltransferase 2 Prevents Diet-Induced Obesity and Insulin Resistance despite Long-Chain Acylcarnitine Accumulation
    1
    1. scibot 14 Nov 2020
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      DOI: 10.1016/j.celrep.2020.108374

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    pubmed.ncbi.nlm.nih.gov/33176143/
  31. www.sciencedirect.com www.sciencedirect.com
    Neuronal Autophagy Regulates Presynaptic Neurotransmission by Controlling the Axonal Endoplasmic Reticulum
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      DOI: 10.1016/j.neuron.2020.10.005

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    sciencedirect.com/science/article/pii/S089662732030773X
  32. Oct 2020
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ReScan, a Multiplex Diagnostic Pipeline, Pans Human Sera for SARS-CoV-2 Antigens
    1
    1. scibot 13 Oct 2020
      RRID:AB_10956166

      DOI: 10.1016/j.xcrm.2020.100123

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    ncbi.nlm.nih.gov/pmc/articles/PMC7513813/
  34. Sep 2020
  35. www.sciencedirect.com www.sciencedirect.com
    Structure-Based Identification and Functional Characterization of a Lipocalin in the Malaria Parasite Plasmodium falciparum
    1
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      DOI: 10.1016/j.celrep.2020.107817

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    sciencedirect.com/science/article/pii/S2211124720307981
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Amyloid‐beta1‐42 induced glutamatergic receptor and transporter expression changes in the mouse hippocampus
    1
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      DOI: 10.1111/jnc.15099

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15099
  37. www.sciencedirect.com www.sciencedirect.com
    Chaperone-Mediated Protein Disaggregation Triggers Proteolytic Clearance of Intra-nuclear Protein Inclusions
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      DOI: 10.1016/j.celrep.2020.107680

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    sciencedirect.com/science/article/pii/S2211124720306331
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    The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death
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      DOI: 10.1016/j.celrep.2020.107547

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    sciencedirect.com/science/article/pii/S2211124720304575
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    Structure of the TSC2 GAP Domain: Mechanistic Insight into Catalysis and Pathogenic Mutations
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      DOI: 10.1016/j.str.2020.05.008

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    sciencedirect.com/science/article/pii/S0969212620301775
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    Small Molecule Dysregulation of TEAD Lipidation Induces a Dominant-Negative Inhibition of Hippo Pathway Signaling
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      DOI: 10.1016/j.celrep.2020.107809

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    sciencedirect.com/science/article/pii/S2211124720307907
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Skd3 (human ClpB) is a potent mitochondrial protein disaggregase that is inactivated by 3-methylglutaconic aciduria-linked mutations
    1
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      DOI: 10.7554/eLife.55279

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    ncbi.nlm.nih.gov/pmc/articles/PMC7343390/
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Rrp6 Moonlights in an RNA Exosome-Independent Manner to Promote Cell Survival and Gene Expression during Stress
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      DOI: 10.1016/j.celrep.2020.107754

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    pubmed.ncbi.nlm.nih.gov/32521279/
  43. www.cell.com www.cell.com
    Plasma Membrane Furrows Control Plasticity of ER-PM Contacts
    1
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    cell.com/cell-reports/abstract/S2211-1247(19)31763-2
  44. www.sciencedirect.com www.sciencedirect.com
    Ago2-Dependent Processing Allows miR-451 to Evade the Global MicroRNA Turnover Elicited during Erythropoiesis
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      DOI: 10.1016/j.molcel.2020.02.020

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    sciencedirect.com/science/article/pii/S1097276520301131
  45. www.sciencedirect.com www.sciencedirect.com
    Imbalanced Host Response to SARS-CoV-2 Drives Development of COVID-19
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      DOI: 10.1016/j.cell.2020.04.026

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    sciencedirect.com/science/article/pii/S009286742030489X
  46. www.jneurosci.org www.jneurosci.org
    Doublecortin like kinase 1 regulates α-Synuclein levels and toxicity
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      DOI: 10.1523/JNEUROSCI.1076-19.2019

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    jneurosci.org/content/40/2/459
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human cytomegalovirus interactome analysis identifies degradation hubs, domain associations and viral protein functions
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      DOI: 10.7554/eLife.49894

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    Translation Initiation Site Profiling Reveals Widespread Synthesis of Non-AUG-Initiated Protein Isoforms in Yeast
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    Fyn Kinase Controls Tau Aggregation In Vivo
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    CenH3-Independent Kinetochore Assembly in Lepidoptera Requires CCAN, Including CENP-T
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    MicroRNA Clustering Assists Processing of Suboptimal MicroRNA Hairpins through the Action of the ERH Protein
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    Differential effects of integrase strand transfer inhibitors, elvitegravir and raltegravir, on oligodendrocyte maturation: A role for the integrated stress response
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    CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles
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    Docosahexaenoic acid protection against palmitic acid‐induced lipotoxicity in NGF differentiated PC12 cells involves enhancement of autophagy and inhibition of apoptosis and necroptosis
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    BET, SRC, and BCL2 family inhibitors are synergistic drug combinations with PARP inhibitors in ovarian cancer
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    GABAergic neurons in the insular cortex play an important role in cue-morphine reward memory reconsolidation
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    RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases
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    Quantifying the Central Dogma in the p53 Pathway in Live Single Cells
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    Deletion of 2‐aminoadipic semialdehyde synthase limits metabolite accumulation in cell and mouse models for glutaric aciduria type 1
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    Impairing committed cholesterol biosynthesis in white matter astrocytes, but not grey matter astrocytes, enhances in vitro myelination
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    Novel Miniaturized Drug Conjugate Leverages HSP90 Driven Tumor Accumulation to Overcome PI3K Inhibitor Delivery Challenges to Solid Tumors
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    Modulation of dopamine D1 receptors via histamine H3 receptors is a novel therapeutic target for Huntington's disease
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    IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation
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    Rare missense variants in the human cytosolic antibody receptor preserve antiviral function
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    Degradation of Polycomb Repressive Complex 2 with an EED-Targeted Bivalent Chemical Degrader
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    Developmental regulation of an organelle tether coordinates mitochondrial remodeling in meiosis
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    Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast
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    The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation
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    Mining Disaggregase Sequence Space to Safely Counter TDP-43, FUS, and α-Synuclein Proteotoxicity
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    Role of hepatic glucocorticoid receptor in metabolism in models of 5αR1 Deficiency in Male Mice
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    6-Phosphogluconate Dehydrogenase Links Cytosolic Carbohydrate Metabolism to Protein Secretion via Modulation of Glutathione Levels
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    A Consensus Binding Motif for the PP4 Protein Phosphatase
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    A Compendium of Genetic Modifiers of Mitochondrial Dysfunction Reveals Intra-organelle Buffering
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    Spatiotemporal Patterning of Zygotic Genome Activation in a Model Vertebrate Embryo
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    N6-Methyladenosine Modification Controls Circular RNA Immunity
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  87. www.sciencedirect.com www.sciencedirect.com
    Modeling and Predicting the Activities of Trans-Acting Splicing Factors with Machine Learning
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      RRID:AB_10956166

      DOI: 10.1016/j.cels.2018.09.002

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  88. academic.oup.com academic.oup.com
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      DOI: 10.1210/en.2018-00603

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1186/s13293-018-0214-6

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  90. Nov 2018
  91. www.sciencedirect.com www.sciencedirect.com
    A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  93. elifesciences.org elifesciences.org
    Non-invasive measurement of mRNA decay reveals translation initiation as the major determinant of mRNA stability
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    Disruption of the β1L Isoform of GABP Reverses Glioblastoma Replicative Immortality in a TERT Promoter Mutation-Dependent Manner
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  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
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    High-Density Proximity Mapping Reveals the Subcellular Organization of mRNA-Associated Granules and Bodies
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    The Dynamics of mRNA Turnover Revealed by Single-Molecule Imaging in Single Cells
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    Nuclear-Import Receptors Reverse Aberrant Phase Transitions of RNA-Binding Proteins with Prion-like Domains
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    Design and Profiling of a Subcellular Targeted Optogenetic cAMP-Dependent Protein Kinase
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    Structural Determinants for Small-Molecule Activation of Skeletal Muscle AMPK α2β2γ1 by the Glucose Importagog SC4
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stress-response transcription factors Msn2 and Msn4 couple TORC2-Ypk1 signaling and mitochondrial respiration to ATG8 gene expression and autophagy
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    Age-Dependent Dopaminergic Neurodegeneration and Impairment of the Autophagy-Lysosomal Pathway in LRRK-Deficient Mice
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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Chemoproteomic Approach to Query the Degradable Kinome Using a Multi-kinase Degrader
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  104. europepmc.org europepmc.org
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  105. europepmc.org europepmc.org
    MELK is not necessary for the proliferation of basal-like breast cancer cells.
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  106. www.sciencedirect.com www.sciencedirect.com
    PTEN Regulates PI(3,4)P2 Signaling Downstream of Class I PI3K
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  107. Nov 2017
  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechano-dependent signaling by Latrophilin/CIRL quenches cAMP in proprioceptive neurons
    1
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    The RNA Surveillance Factor UPF1 Represses Myogenesis via Its E3 Ubiquitin Ligase Activity
    1
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      IRDye 680RD Goat anti-Rabbit IgG (H + L)LI-CORP/N 926-68071

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  110. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transgenerational programming of longevity through E(z)-mediated histone H3K27 trimethylation in Drosophila
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  111. elifesciences.org elifesciences.org
    ATPase activity of the DEAD-box protein Dhh1 controls processing body formation
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      Curator: @kaitlinsung

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    elifesciences.org/content/5/e18746
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    A conserved quality-control pathway that mediates degradation of unassembled ribosomal proteins
    2
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      AB_10956166

      Curator: @gabimpine

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