2,147 Matching Annotations
  1. Jul 2024
  2. www.cell.com www.cell.com
    A highly potent bi-thiazole inhibitor of LOX rewires collagen architecture and enhances chemoresponse in triple-negative breast cancer
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    cell.com/cell-chemical-biology/fulltext/S2451-9456(24)00273-3
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    Transcriptional programming mediated by the histone demethylase KDM5C regulates dendritic cell population heterogeneity and function
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    sciencedirect.com/science/article/pii/S2211124724008350
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    Melatonin alleviates high-fat-diet-induced dry eye by regulating macrophage polarization via IFT27 and lowering ERK/JNK phosphorylation
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    Genome-scale exon perturbation screens uncover exons critical for cell fitness
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    cell.com/molecular-cell/abstract/S1097-2765(24)00447-7
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    G protein–coupled receptor endocytosis generates spatiotemporal bias in β-arrestin signaling
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    The centrosomal protein FGFR1OP controls myosin function in murine intestinal epithelial cells
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    Ceramide-induced cleavage of GPR64 intracellular domain drives Ewing sarcoma
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    cell.com/cell-reports/fulltext/S2211-1247(24)00826-X
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    The splicing factor CCAR1 regulates the Fanconi anemia/BRCA pathway
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    Kufor-Rakeb syndrome-associated psychosis: a novel loss-of-function ATP13A2 variant and response to antipsychotic therapy
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  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding sunitinib resistance in ccRCC: Metabolic-reprogramming-induced ABAT and GABAergic system shifts
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    Retinoic acid enhances HIV-1 reverse transcription and transcription in macrophages via mTOR-modulated mechanisms
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    The antagonistic role of an E3 ligase pair in regulating plant NLR-mediated autoimmunity and fungal pathogen resistance
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    Hepatocyte-macrophage crosstalk via the PGRN-EGFR axis modulates ADAR1-mediated immunity in the liver
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    Metabolomics of repetitive myocardial stunning in chronic multivessel coronary artery stenosis: Effect of non-selective and selective β1-receptor blockers
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    RHOF Activation of AKT/β-Catenin Signaling Pathway Drives Acute Myeloid Leukemia Progression and Chemotherapy Resistance
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    Small molecule inhibitor binds to NOD-like receptor family pyrin domain containing 3 and prevents inflammasome activation
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    Neddylation inhibition prevents acetaminophen-induced liver damage by enhancing the anabolic cardiolipin pathway
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    Multi-step regulation of microRNA expression and secretion into small extracellular vesicles by insulin
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    Multivalent GU-rich oligonucleotides sequester TDP-43 in the nucleus by inducing high molecular weight RNP complexes
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    Tumor-intrinsic P2RY6 drives immunosuppression by enhancing PGE2 production
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    HER4 Affects Sensitivity to Tamoxifen and Abemaciclib in Luminal Breast Cancer Cells and Restricts Tumor Growth in MCF-7-Based Humanized Tumor Mice
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Preventing loss of sirt1 lowers mitochondrial oxidative stress and preserves c2c12 myotube diameter in an in vitro model of cancer cachexia
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    Actinomycin D and bortezomib disrupt protein homeostasis in Wilms tumor
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    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Placental co-transcriptional activator Vestigial-like 1 (VGLL1) drives tumorigenesis via increasing transcription of proliferation and invasion genes
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  28. Jun 2024
  29. www.cell.com www.cell.com
    Oxygen tension-dependent variability in the cancer cell kinome impacts signaling pathways and response to targeted therapies
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    CHK1 inhibitor SRA737 is active in PARP inhibitor resistant and CCNE1 amplified ovarian cancer
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    FoxO1 suppresses Fgf21 during hepatic insulin resistance to impair peripheral glucose utilization and acute cold tolerance
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    The phosphorylation-deubiquitination positive feedback loop of the CHK2-USP7 axis stabilizes p53 under oxidative stress
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    Electron transport chain inhibition increases cellular dependence on purine transport and salvage
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    A spatiotemporal map of co-receptor signaling networks underlying B cell activation
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  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal sphingosine-1-phosphate receptor 3 expression within the cerebral vasculature after ischemic stroke
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  36. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
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  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-tumor effects of tirbanibulin in squamous cell carcinoma cells are mediated via disruption of tubulin-polymerization
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Evaluation of the role of AXL in fusion-positive pediatric rhabdomyosarcoma identifies the small-molecule inhibitor bemcentinib (BGB324) as potent chemosensitizer
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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subpopulation of luminal progenitors secretes pleiotrophin to promote angiogenesis and metastasis in inflammatory breast cancer
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The exonuclease TREX1 constitutes an innate immune checkpoint limiting cGAS/STING-mediated antitumor immunity
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    Islet cell stress induced by insulin-degrading enzyme deficiency promotes regeneration and protection from autoimmune diabetes
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    Demethylase FTO-mediated m6A modification of SIK1 modulates placental cytotrophoblast syncytialization in type 2 diabetes mellitus.
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    Endurance training increases mitochondrial myoglobin and enhances its interaction with complex IV in rat plantaris muscle
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    Assembly of neuron- and radial glial-cell-derived extracellular matrix molecules promotes radial migration of developing cortical neurons
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    MYC dependency in GLS1 and NAMPT is a therapeutic vulnerability in multiple myeloma
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    Structural dynamics of the active HER4 and HER2/HER4 complexes is finely tuned by different growth factors and glycosylation
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    SUMOylation controls Hu antigen R posttranscriptional activity in liver cancer
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    Peripheral amyloid-β clearance mediates cognitive impairment in non-alcoholic fatty liver disease
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    Single-cell omics identifies inflammatory signaling as a trans-differentiation trigger in mouse embryos
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    P-tau217 correlates with neurodegeneration in Alzheimer’s disease, and targeting p-tau217 with immunotherapy ameliorates murine tauopathy
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    Protocol for the isolation of tumor cell-derived extracellular vesicles followed by in vivo metastasis assessment in a murine ovarian cancer model
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    SMARCA4 is a haploinsufficient B cell lymphoma tumor suppressor that fine-tunes centrocyte cell fate decisions
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    ARID1A orchestrates SWI/SNF-mediated sequential binding of transcription factors with ARID1A loss driving pre-memory B cell fate and lymphomagenesis
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    RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma
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    Mechanisms of HIV-Mediated Blood-Brain Barrier Compromise and Leukocyte Transmigration under the Current Antiretroviral Era.
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    Cellular senescence is associated with the spatial evolution toward a higher metastatic phenotype in colorectal cancer
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    Liver-derived plasminogen mediates muscle stem cell expansion during caloric restriction through the plasminogen receptor Plg-RKT
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