552 Matching Annotations
  1. Oct 2023
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dendritic distribution of autophagosomes underlies pathway-selective induction of LTD
    1
    1. scibot 06 Oct 2023
      RRID:AB_2107436

      DOI: 10.1016/j.celrep.2023.112898

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    ncbi.nlm.nih.gov/pmc/articles/PMC10528062/
  3. www.sciencedirect.com www.sciencedirect.com
    CPSF6 regulates alternative polyadenylation and proliferation of cancer cells through phase separation
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113197

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    sciencedirect.com/science/article/pii/S2211124723012093
  4. Sep 2023
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.isci.2023.107823

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    ncbi.nlm.nih.gov/pmc/articles/PMC10514451/
  6. www.sciencedirect.com www.sciencedirect.com
    Signaling protein abundance modulates the strength of the spindle assembly checkpoint
    1
    1. scibot 30 Sep 2023
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      DOI: 10.1016/j.cub.2023.08.074

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    sciencedirect.com/science/article/pii/S0960982223011545
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroepithelial cell-transforming 1 promotes cardiac fibrosis via the wnt/β-catenin signaling pathway
    1
    1. scibot 29 Sep 2023
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  8. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Su-html.html
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    1. scibot 22 Sep 2023
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    52.53.155.43/78b3cb40c26a3e87d0e680de40f4d0777a8366ee/British J Pharmacology - 2023 - Su-html.html
  9. academic.oup.com academic.oup.com
    bvad117-html.html
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    1. scibot 20 Sep 2023
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      DOI: 10.1210/jendso/bvad117

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      DOI: 10.1210/jendso/bvad117

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    academic.oup.com/jes/article/7/10/bvad117/7274808
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    Spinal TAOK2 contributes to neuropathic pain via cGAS-STING activation in rats
    1
    1. scibot 16 Sep 2023
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    sciencedirect.com/science/article/pii/S2589004223018692
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    Mitoquinone alleviates osteoarthritis progress by activating the NRF2-Parkin axis
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1016/j.isci.2023.107647

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    sciencedirect.com/science/article/pii/S2589004223017248
  12. Aug 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Selective ATP-Competitive CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function
    1
    1. scibot 31 Aug 2023
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      DOI: 10.21203/rs.3.rs-3182731/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10441460/
  14. www.biorxiv.org www.biorxiv.org
    Unraveling Vulnerabilities in Endocrine Therapy-Resistant HER2+/ER+ Breast Cancer
    1
    1. scibot 27 Aug 2023
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      DOI: 10.1101/2023.08.21.554116

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    biorxiv.org/content/10.1101/2023.08.21.554116v1
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Increased NMDARs in neurons and glutamine synthetase in astrocytes underlying autistic-like behaviors of Gabrb1-/- mice
    1
    1. scibot 26 Aug 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10433130/
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    Cell-type-specific regulation of APOE and CLU levels in human neurons by the Alzheimer’s disease risk gene SORL1
    1
    1. scibot 23 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112994

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  17. 52.53.155.43 52.53.155.43
    The miR-17∼92 miRNAs promote plasma cell differentiation by suppressing SOCS3-mediated NIK degradation
    2
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112968

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    52.53.155.43/8a075ef675e11ca05cb4fe9fd629f036036ec570/PIIS2211124723009798-html.html
  18. 52.53.155.43 52.53.155.43
    NFYC-37 promotes tumor growth by activating the mevalonate pathway in bladder cancer
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112963

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    2. scibot 10 Aug 2023
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    52.53.155.43/eb7aace05cf7a189f4453bfbeb3bcf344412f769/mmc4-html.html
  19. 52.53.155.43 52.53.155.43
    MOF-mediated acetylation of SIRT6 disrupts SIRT6-FOXA2 interaction and represses SIRT6 tumor-suppressive function by upregulating ZEB2 in NSCLC
    2
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112939

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    2. scibot 11 Aug 2023
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    52.53.155.43/bd09065dee8428d4c17fca329effba1c6cc59b0c/PIIS2211124723009506-html.html
  20. www.sciencedirect.com www.sciencedirect.com
    Hyodeoxycholic acid alleviates non-alcoholic fatty liver disease through modulating the gut-liver axis
    1
    1. scibot 17 Aug 2023
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      DOI: 10.1016/j.cmet.2023.07.011

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    sciencedirect.com/science/article/pii/S155041312300270X
  21. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Han-html.html
    1
    1. scibot 16 Aug 2023
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      DOI: 10.1111/bph.16208

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    52.53.155.43/5e554e9cedd6e38ae632f7a8eb735fb3080af333/British J Pharmacology - 2023 - Han-html.html
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PAK1 contributes to cerebral ischemia/reperfusion injury by regulating the blood-brain barrier integrity
    1
    1. scibot 02 Aug 2023
      RRID:AB_2107436

      DOI: 10.1016/j.isci.2023.107333

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    ncbi.nlm.nih.gov/pmc/articles/PMC10387573/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
    1
    1. scibot 02 Aug 2023
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      DOI: 10.2337/db22-1016

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    ncbi.nlm.nih.gov/pmc/articles/PMC10382653/
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    Magneto-mechanical stimulation modulates osteocyte fate via the ECM-integrin-CSK axis and wnt pathway
    1
    1. scibot 02 Aug 2023
      RRID:AB_210743

      DOI: 10.1016/j.isci.2023.107365

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    sciencedirect.com/science/article/pii/S2589004223014426
  25. 52.53.155.43 52.53.155.43
    BPS Publications
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    52.53.155.43/d8c850c315bd1ef9a1794152cac296a4123affe5/British J Pharmacology - 2023 - Wang - Sanguinarine induces apoptosis in osteosarcoma by attenuating the binding of STAT3-html.html
  26. Jul 2023
  27. www.sciencedirect.com www.sciencedirect.com
    STING-IRG1 inhibits liver metastasis of colorectal cancer by regulating the polarization of tumor-associated macrophages
    1
    1. scibot 29 Jul 2023
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      DOI: 10.1016/j.isci.2023.107376

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    sciencedirect.com/science/article/pii/S2589004223014530
  28. www.embopress.org www.embopress.org
    Interferon inhibits a model RNA virus via a limited set of inducible effector genes
    1
    1. scibot 29 Jul 2023
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      DOI: 10.15252/embr.202356901

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    embopress.org/doi/10.15252/embr.202356901
  29. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
    1
    1. scibot 27 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112869

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    sciencedirect.com/science/article/pii/S221112472300880X
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
    1
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      DOI: 10.1016/j.celrep.2023.112833

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    sciencedirect.com/science/article/pii/S2211124723008446
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative transcriptome profiling of Eimeria tenella in various developmental stages and functional analysis of an ApiAP2 transcription factor exclusively expressed during sporogony
    1
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      DOI: 10.1186/s13071-023-05828-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10354945/
  32. www.sciencedirect.com www.sciencedirect.com
    AAV-GRN partially corrects motor deficits and ALS/FTLD-related pathology in Tmem106b-/-Grn-/- mice
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      DOI: 10.1016/j.isci.2023.107247

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    sciencedirect.com/science/article/pii/S258900422301324X
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    A Proximity Labeling Strategy Enables Proteomic Analysis of Inter-organelle Membrane Contacts
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      DOI: 10.1016/j.isci.2023.107159

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    sciencedirect.com/science/article/pii/S2589004223012361
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    ALKBH5 causes retinal pigment epithelium anomalies and choroidal neovascularization in age-related macular degeneration via the AKT/mTOR pathway
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    sciencedirect.com/science/article/pii/S2211124723007908
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eph receptor A4 regulates motor neuron ferroptosis in spinal cord ischemia/reperfusion injury in rats
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      DOI: 10.4103/1673-5374.369118

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    ncbi.nlm.nih.gov/pmc/articles/PMC10328289/
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    M2 macrophages mediate fibrotic scar formation in the early stages after cerebral ischemia in rats
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    ncbi.nlm.nih.gov/pmc/articles/PMC10328259/
  37. 52.53.155.43 52.53.155.43
    Blocking an epitope of misfolded SOD1 ameliorates disease phenotype in a model of amyotrophic lateral sclerosis
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      DOI: 10.1093/brain/awad222

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    Hepatic soluble epoxide hydrolase activity regulates cerebral Aβ metabolism and the pathogenesis of Alzheimer’s disease in mice
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      DOI: 10.1016/j.neuron.2023.06.002

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    sciencedirect.com/science/article/pii/S0896627323004373
  39. www.sciencedirect.com www.sciencedirect.com
    Glibenclamide promotes FGF21 secretion in interscapular BAT and attenuates depression-like behaviors in male mice with HFD-induced obesity
    1
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      DOI: 10.1016/j.lfs.2023.121900

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  40. Jun 2023
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    Akt2 deficiency alleviates oxidative stress in the heart and liver via upregulating SIRT6 during high-fat diet-induced obesity
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    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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    Suppression of TREX1 Deficiency-Induced Cellular Senescence and Interferonopathies by Inhibition of DNA Damage Response
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    Immunosensitivity mediated by downregulated AKT1-SKP2 induces anti-PD-1-associated thyroid immune injury
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    The m6A Reader YTHDF2 Promotes Bladder Cancer Progression by Suppressing RIG-I–Mediated Immune Response
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    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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    Methionine restriction promotes cGAS activation and chromatin untethering through demethylation to enhance antitumor immunity
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    FAM210A Regulates Mitochondrial Translation and Maintains Cardiac Mitochondrial Homeostasis
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    16p11.2 haploinsufficiency reduces mitochondrial biogenesis in brain endothelial cells and alters brain metabolism in adult mice
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    CX3CR1hi macrophages sustain metabolic adaptation by relieving adipose-derived stem cell senescence in visceral adipose tissue
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    YTHDF1 phase separation triggers the fate transition of spermatogonial stem cells by activating the IκB-NF-κB-CCND1 axis
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    Differential and substrate-specific inhibition of γ-secretase by the C-terminal region of ApoE2, ApoE3, and ApoE4
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    PPDPF suppresses the development of hepatocellular carcinoma through TRIM21-mediated ubiquitination of RIPK1
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    Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
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    Senomorphic effect of diphenyleneiodonium through AMPK/MFF/DRP1 mediated mitochondrial fission
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    Renal CD81 interacts with sodium potassium 2 chloride cotransporter and sodium chloride cotransporter in rats with lipopolysaccharide-induced preeclampsia
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    Mitoguardin2 is Associated with Hyperandrogenism and Regulates Steroidogenesis in Human Ovarian Granulosa Cells
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    Aspergillus fumigatus hijacks human p11 to redirect fungal-containing phagosomes to non-degradative pathway
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    Chemoproteomics-enabled discovery of a covalent molecular glue degrader targeting NF-κB
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    Prolyl isomerase Pin1 promotes extracellular matrix production in hepatic stellate cells through regulating formation of the Smad3-TAZ complex
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    COUP-TFII plays a role in cAMP-induced Schwann cell differentiation and in vitro myelination by upregulating Krox20
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    Disturbed rhythmicity of intestinal hydrogen peroxide alters gut microbial oscillations in BMAL1-deficient monkeys
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    Skeletal dysplasia-causing TRPV4 mutations suppress the hypertrophic differentiation of human iPSC-derived chondrocytes
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    PPT1 Regulation Of HSP90α Depalmitoylation Participates In The Pathogenesis Of Hyperandrogenism
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    iTRAQ-based proteomic analysis unveils ACSL4 as a novel potential regulator of human endometrial receptivity
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    N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis
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    A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
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    Hypoxic postconditioning restores mitophagy against transient global cerebral ischemia via Parkin-induced posttranslational modification of TBK1
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    Repositioning Lomitapide to block ZDHHC5-dependant palmitoylation on SSTR5 leads to anti-proliferation effect in preclinical pancreatic cancer models
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    VPS35 promotes cell proliferation via EGFR recycling and enhances EGFR inhibitors response in gastric cancer
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    Loss of C3a and C5a receptors promotes adipocyte browning and attenuates diet-induced obesity via activating inosine/A2aR pathway
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    Stabilization of nuclear β-catenin by inhibiting KDM2A mediates cerebral ischemic tolerance
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    Intrahippocampal injection of IL-1β upregulates Siah1-mediated degradation of synaptophysin by activation of the ERK signaling in male rat
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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    Yishen Xiezhuo formula ameliorates the development of cisplatin-induced acute kidney injury by attenuating renal tubular epithelial cell senescence
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    Intersection of immune and oncometabolic pathways drives cancer hyperprogression during immunotherapy
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    Inhibition of interaction between ROCK1 and Rubicon restores autophagy in endothelial cells and attenuates brain injury after prolonged ischemia
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    SETDB1 Restrains Endogenous Retrovirus Expression and Antitumor Immunity during Radiotherapy
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    Disrupting Circadian Rhythm via the PER1–HK2 Axis Reverses Trastuzumab Resistance in Gastric Cancer
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ischemic accumulation of succinate induces Cdc42 succinylation and inhibits neural stem cell proliferation after cerebral ischemia/reperfusion
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    Decreased expression of EZH2 in granulosa cells contributes to endometriosis-associated infertility by targeting IL-1R2
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    Alternative transcribed 3' isoform of long non-coding RNA Malat1 inhibits mouse retinal oxidative stress
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    Centrosomal Protein 120 Promotes Centrosome Amplification And Gastric Cancer Progression Via USP54-Mediated Deubiquitination Of PLK4
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    The deubiquitinase OTUD1 noncanonically suppresses Akt activation through its N-terminal intrinsically disordered region
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  129. Dec 2022
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    DNA damage repair kinase DNA-PK and cGAS synergize to induce cancer-related inflammation in glioblastoma
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    Allosteric Inhibition of c-Abl to Induce Unfolded Protein Response and Cell Death in Multiple Myeloma
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    Immunological profiles of human oligodendrogliomas define two distinct molecular subtypes
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    TGF-β2 Regulates Transcription of the K+/Cl− Cotransporter 2 (KCC2) in Immature Neurons and Its Phosphorylation at T1007 in Differentiated Neurons
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    Copper transporter gene ATP7A: A predictive biomarker for immunotherapy and targeted therapy in hepatocellular carcinoma
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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    Vagus nerve stimulation is a potential treatment for ischemic stroke
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    Social deficits via dysregulated Rac1-dependent excitability control of prefrontal cortical neurons and increased GABA/glutamate ratios
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    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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  139. Nov 2022
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    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
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    circPRKAA1 activates a Ku80/Ku70/SREBP-1 axis driving de novo fatty acid synthesis in cancer cells
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    Biofabrication of synthetic human liver tissue with advanced programmable functions
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    Parkinson’s disease-associated Leucine-rich repeat kinase regulates UNC-104-dependent axonal transport of Arl8-positive vesicles in Drosophila
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    m6A modification of circSPECC1 suppresses RPE oxidative damage and maintains retinal homeostasis
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    Lactobacillus reuteri normalizes altered fear memory in male Cntnap4 knockout mice
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    Driving axon regeneration by orchestrating neuronal and non-neuronal innate immune responses via the IFNγ-cGAS-STING axis
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    Disease-associated mutations in WDR34 lead to diverse impacts on the assembly and function of dynein-2
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    Leukemia inhibitory factor is a therapeutic target for renal interstitial fibrosis
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    Cancer cell intrinsic TIM-3 induces glioblastoma progression
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    Acute depletion of human core nucleoporin reveals direct roles in transcription control but dispensability for 3D genome organization
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  152. Oct 2022
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    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
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    An alternative mechanism for skeletal muscle dysfunction in long-term post-viral lung disease
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    Vimentin inhibits type I interferon production by disrupting the TBK1-IKKε-IRF3 axis
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    Calcium transients on the ER surface trigger liquid-liquid phase separation of FIP200 to specify autophagosome initiation sites
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    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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  158. Sep 2022
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    cGAS-STING Activation by Cytosolic Mitochondrial DNA Contributes to Podocyte Injury in Diabetic Kidney Disease
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    Confined migration induces heterochromatin formation and alters chromatin accessibility
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    CTCF DNA-binding domain undergoes dynamic and selective protein–protein interactions
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  162. onlinelibrary.wiley.com onlinelibrary.wiley.com
    m5C writer NSUN3 promotes tumor progression by regulating immune infiltration in HNSCC
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    A covalent inhibitor of K-Ras(G12C) induces MHC class I presentation of haptenated peptide neoepitopes targetable by immunotherapy
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    Micronuclei from misaligned chromosomes that satisfy the spindle assembly checkpoint in cancer cells
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  165. Aug 2022
  166. www.sciencedirect.com www.sciencedirect.com
    MicroRNA-21-5p agomir inhibits apoptosis of oligodendrocyte precursor cell and attenuates white matter injury in neonatal rats
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    Aberrant human ClpP activation disturbs mitochondrial proteome homeostasis to suppress pancreatic ductal adenocarcinoma
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    Obese Skeletal Muscle-Expressed Interferon Regulatory Factor 4 Transcriptionally Regulates Mitochondrial Branched-Chain Aminotransferase Reprogramming Metabolome
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    Microtubule associated protein 4 phosphorylation-induced epithelial-to-mesenchymal transition of podocyte leads to proteinuria in diabetic nephropathy
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  176. Jun 2022
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    The Role of Ciliopathy-Associated Type 3 Adenylyl Cyclase in Infanticidal Behavior in Virgin Adult Male Mice
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    Oxidative stress from DGAT1 oncoprotein inhibition in melanoma suppresses tumor growth when ROS defenses are also breached
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    GCN5 participates in KLF4-VEGFA feedback to promote endometrial angiogenesis
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  183. May 2022
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    Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles
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    Study of novel NARS2 variants in patient of combined oxidative phosphorylation deficiency 24
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  187. Apr 2022
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    Functional genetic screen identifies ITPR3/calcium/RELB axis as a driver of colorectal cancer metastatic liver colonization
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    Linkage of methionine addiction, histone lysine hypermethylation, and malignancy
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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    Nicotinamide N-methyltransferase ameliorates renal fibrosis by its metabolite 1-methylnicotinamide inhibiting the TGF-β1/Smad3 pathway
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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Annexin A7 and JNK knockdown suppress the lymphatic metastasis potential of hepatocellular carcinoma cells: Possible contributions of ATF2 and sequence-related lncRNA NONMMUT114121.1
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      RRID:AB_2107436

      DOI: 10.21037/tcr-20-2111

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    ncbi.nlm.nih.gov/pmc/articles/PMC8798967/
  212. www.sciencedirect.com www.sciencedirect.com
    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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    1. scibot 04 Feb 2022
      RRID:AB_2107436

      DOI: 10.1016/j.molcel.2022.01.002

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    sciencedirect.com/science/article/pii/S1097276522000028
  213. Jan 2022
  214. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Elucidation of pathological mechanism caused by human disease mutation in CaMKIIβ
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    1. scibot 27 Jan 2022
      AB_2107436

      DOI: 10.1002/jnr.25013

      Resource: (Proteintech Cat# 60004-1-Ig, RRID:AB_2107436)

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    onlinelibrary.wiley.com/doi/10.1002/jnr.25013