273 Matching Annotations
  1. Sep 2020
  2. journals.physiology.org journals.physiology.org
    A common genetic variant in zinc transporter ZnT2 (Thr288Ser) is present in women with low milk volume and alters lysosome function and cell energetics | American Journal of Physiology-Cell Physiology
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      DOI: 10.1152/ajpcell.00383.2019

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    journals.physiology.org/doi/full/10.1152/ajpcell.00383.2019
  3. Jan 2020
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    Suppression of p16 Induces mTORC1-Mediated Nucleotide Metabolic Reprogramming
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    sciencedirect.com/science/article/pii/S2211124719310009
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    NOX1-Dependent mTORC1 Activation via S100A9 Oxidation in Cancer Stem-like Cells Leads to Colon Cancer Progression
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    The RING-type E3 ligase RNF186 ubiquitinates Sestrin-2 and thereby controls nutrient sensing
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      DOI: 10.1074/jbc.AC119.010671

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    Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses
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      DOI: 10.1016/j.immuni.2019.06.007

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    sciencedirect.com/science/article/pii/S1074761319302778
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    Discovery of Small-Molecule Selective mTORC1 Inhibitors via Direct Inhibition of Glucose Transporters
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    sciencedirect.com/science/article/pii/S2451945619301783
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    TRPML1 Promotes Protein Homeostasis in Melanoma Cells by Negatively Regulating MAPK and mTORC1 Signaling
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    Mechanical loading stimulates hypertrophy in tissue‐engineered skeletal muscle: Molecular and phenotypic responses
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      DOI: 10.1002/jcp.28923

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    Phosphoethanolamine Accumulation Protects Cancer Cells under Glutamine Starvation through Downregulation of PCYT2
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    sciencedirect.com/science/article/pii/S2211124719311490
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    Acylglycerol Kinase Maintains Metabolic State and Immune Responses of CD8+ T Cells
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    cell.com/cell-metabolism/fulltext/S1550-4131(19)30256-6
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    Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs
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    Effects of the presence and absence of amino acids on translation, signaling and long‐term depression in hippocampal slices from Fmr1 knockout mice
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      DOI: 10.1111/jnc.14874

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    Small-Molecule and CRISPR Screening Converge to Reveal Receptor Tyrosine Kinase Dependencies in Pediatric Rhabdoid Tumors
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    Lovastatin, not Simvastatin, Corrects Core Phenotypes in the Fragile X Mouse Model
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      DOI: 10.1523/ENEURO.0097-19.2019

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    ncbi.nlm.nih.gov/pmc/articles/PMC6565377/
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    Transient Receptor Potential V Channels Are Essential for Glucose Sensing by Aldolase and AMPK
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    Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer’s Disease Neurons
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      DOI: 10.1016/j.molcel.2018.12.017

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    sciencedirect.com/science/article/pii/S2211124719300282
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    Lysosome Positioning Influences mTORC2 and AKT Signaling
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    sciencedirect.com/science/article/pii/S1097276519303624
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    PI3K inhibitors protect against glucocorticoid-induced skin atrophy
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      DOI: 10.1016/j.ebiom.2019.01.055

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    sciencedirect.com/science/article/pii/S2352396419300428
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    The Osteogenic Niche Is a Calcium Reservoir of Bone Micrometastases and Confers Unexpected Therapeutic Vulnerability
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      DOI: 10.1016/j.neulet.2018.11.018

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    Nucleoporin Seh1 Interacts with Olig2/Brd7 to Promote Oligodendrocyte Differentiation and Myelination
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      DOI: 10.1016/j.neuron.2019.02.018

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    New Noonan syndrome model mice with RIT1 mutation exhibit cardiac hypertrophy and susceptibility to β-adrenergic stimulation-induced cardiac fibrosis
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  37. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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      DOI: 10.1111/bph.14626

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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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    sciencedirect.com/science/article/pii/S1097276519302588
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    Transmembrane 4 L Six Family Member 5 Senses Arginine for mTORC1 Signaling
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    sciencedirect.com/science/article/pii/S1550413119301330
  40. Nov 2018
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    TLR8-Mediated Metabolic Control of Human Treg Function: A Mechanistic Target for Cancer Immunotherapy
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    sciencedirect.com/science/article/pii/S1550413118306284
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    sciencedirect.com/science/article/pii/S1550413118305667
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    Leucine Signals to mTORC1 via Its Metabolite Acetyl-Coenzyme A
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    Brown Adipose Tissue Controls Skeletal Muscle Function via the Secretion of Myostatin
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    In Vivo Decoding Mechanisms of the Temporal Patterns of Blood Insulin by the Insulin-AKT Pathway in the Liver
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    mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation
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    The GSK3 Signaling Axis Regulates Adaptive Glutamine Metabolism in Lung Squamous Cell Carcinoma
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    SOD1 Phosphorylation by mTORC1 Couples Nutrient Sensing and Redox Regulation
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    Low-Protein Diet Induces IRE1α-Dependent Anticancer Immunosurveillance
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    GRASP55 Senses Glucose Deprivation through O-GlcNAcylation to Promote Autophagosome-Lysosome Fusion
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    Decreased rates of cerebral protein synthesis measured in vivo in a mouse model of Tuberous Sclerosis Complex: unexpected consequences of reduced tuberin
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    Roquin Suppresses the PI3K-mTOR Signaling Pathway to Inhibit T Helper Cell Differentiation and Conversion of Treg to Tfr Cells
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    Sensing and Transmitting Intracellular Amino Acid Signals through Reversible Lysine Aminoacylations
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    mTORC1 Inactivation Promotes Colitis-Induced Colorectal Cancer but Protects from APC Loss-Dependent Tumorigenesis
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  66. Nov 2017
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    Prosapip1-Dependent Synaptic Adaptations in the Nucleus Accumbens Drive Alcohol Intake, Seeking, and Reward
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    Focal Adhesion- and IGF1R-Dependent Survival and Migratory Pathways Mediate Tumor Resistance to mTORC1/2 Inhibition
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    Germinal Center Selection and Affinity Maturation Require Dynamic Regulation of mTORC1 Kinase
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    DGAT1-Dependent Lipid Droplet Biogenesis Protects Mitochondrial Function during Starvation-Induced Autophagy
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    Fasting-Mimicking Diet Promotes Ngn3-Driven β-Cell Regeneration to Reverse Diabetes
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    SF-1 expression in the hypothalamus is required for beneficial metabolic effects of exercise
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