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Mar 2023
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METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2

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1. scibot 03 Mar 2023
  
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  DOI: 10.1016/j.celrep.2023.112150
  
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sciencedirect.com/science/article/pii/S2211124723001614
Feb 2023
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Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein

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  DOI: 10.1016/j.chom.2023.01.014
  
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sciencedirect.com/science/article/pii/S1931312823000392
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N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis

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1. scibot 17 Feb 2023
  
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  DOI: 10.1016/j.chembiol.2023.01.006
  
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sciencedirect.com/science/article/pii/S2451945623000296
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Aberrant phase separation and nucleolar dysfunction in rare genetic diseases

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  DOI: 10.1038/s41586-022-05682-1
  
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nature.com/articles/s41586-022-05682-1
onlinelibrary.wiley.com onlinelibrary.wiley.com

Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults

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  DOI: 10.1002/glia.24346
  
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onlinelibrary.wiley.com/doi/10.1002/glia.24346
Jan 2023
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Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation

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  DOI: 10.1016/j.celrep.2022.111965
  
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sciencedirect.com/science/article/pii/S2211124722018691
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Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma

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1. scibot 12 Jan 2023
  
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  DOI: 10.1158/0008-5472.CAN-21-3868
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9256772/
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METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism

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1. scibot 06 Jan 2023
  
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  DOI: 10.1016/j.stem.2022.12.006
  
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sciencedirect.com/science/article/pii/S1934590922004908
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Axonal plasticity in response to active forces generated through magnetic nano-pulling

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1. scibot 02 Jan 2023
  
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  DOI: 10.1016/j.celrep.2022.111912
  
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sciencedirect.com/science/article/pii/S2211124722018113
Nov 2022
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m6A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation

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1. scibot 24 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111693
  
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sciencedirect.com/science/article/pii/S2211124722015674
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Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response

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1. scibot 17 Nov 2022
  
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  DOI: 10.1016/j.cmet.2022.10.011
  
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sciencedirect.com/science/article/pii/S1550413122004892
Oct 2022
elifesciences.org elifesciences.org

GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis

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1. scibot 19 Oct 2022
  
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  DOI: 10.7554/eLife.81083
  
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elifesciences.org/articles/81083
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Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities

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1. scibot 14 Oct 2022
  
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  DOI: 10.3389/fcell.2022.952832
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9552079/
Jul 2022
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Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging

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1. scibot 30 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111131
  
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sciencedirect.com/science/article/pii/S2211124722009378
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GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment

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1. scibot 15 Jul 2022
  
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  DOI: 10.1016/j.cmet.2022.06.010
  
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sciencedirect.com/science/article/pii/S1550413122002303
www.embopress.org www.embopress.org

Neuron-specific translational control shift ensures proteostatic resilience during ER stress

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1. scibot 07 Jul 2022
  
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  DOI: 10.15252/embj.2021110501
  
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embopress.org/doi/10.15252/embj.2021110501
Jun 2022
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can-21-3868-html.html

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1. scibot 30 Jun 2022
  
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  DOI: 10.1158/0008-5472.can-21-3868
  
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2. scibot 24 Jun 2022
  
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  DOI: 10.1158/0008-5472.can-21-3868
  
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52.53.155.43/28b9d48499bd7231fb316ef079ea180b1643cc31/can-21-3868 (1)-html.html
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Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A

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1. scibot 25 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104518
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9218363/
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pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains

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1. scibot 25 Jun 2022
  
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  DOI: 10.1016/j.isci.2022.104516
  
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sciencedirect.com/science/article/pii/S2589004222007878
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Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.neuron.2022.05.024
  
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sciencedirect.com/science/article/pii/S0896627322005013
May 2022
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Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

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1. scibot 26 May 2022
  
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  DOI: 10.1016/j.celrep.2022.110860
  
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sciencedirect.com/science/article/pii/S2211124722006337
Apr 2022
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CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60

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1. scibot 14 Apr 2022
  
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  DOI: 10.1016/j.celrep.2022.110635
  
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sciencedirect.com/science/article/pii/S2211124722003874
Feb 2022
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TBK1-METTL3 axis facilitates antiviral immunity

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1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.celrep.2022.110373
  
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pubmed.ncbi.nlm.nih.gov/35172162/
Dec 2021
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RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth

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1. scibot 29 Dec 2021
  
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  DOI: 10.1016/j.isci.2021.103616
  
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Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation

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1. scibot 17 Dec 2021
  
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  DOI: 10.3389/fphys.2021.779547
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8669767/
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Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice

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1. scibot 04 Dec 2021
  
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  DOI: 10.3390/cells10123314
  
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mdpi.com/2073-4409/10/12/3314/htm
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Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis

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  DOI: 10.1016/j.isci.2021.103396
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8605100/
Nov 2021
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Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly

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1. scibot 24 Nov 2021
  
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  DOI: 10.7554/eLife.71575
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8598234/
elifesciences.org elifesciences.org

mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion

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1. scibot 24 Nov 2021
  
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  DOI: 10.7554/eLife.69015
  
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elifesciences.org/articles/69015
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RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site

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1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109934
  
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sciencedirect.com/science/article/pii/S2211124721014078
Sep 2021
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The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation

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1. scibot 23 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.08.033
  
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sciencedirect.com/science/article/pii/S1097276521007139
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Increased fidelity of protein synthesis extends lifespan

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1. scibot 15 Sep 2021
  
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  DOI: 10.1016/j.cmet.2021.08.017
  
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sciencedirect.com/science/article/pii/S1550413121004174
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Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation

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1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.celrep.2021.109659
  
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sciencedirect.com/science/article/pii/S2211124721011037
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A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP

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1. scibot 03 Sep 2021
  
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  DOI: 10.1016/j.chembiol.2021.08.006
  
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sciencedirect.com/science/article/pii/S2451945621003950
Aug 2021
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Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy

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1. scibot 28 Aug 2021
  
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  DOI: 10.1016/j.molcel.2021.07.038
  
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sciencedirect.com/science/article/pii/S1097276521006225
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Channeling macrophage polarization by rocaglates increases macrophage resistance to Mycobacterium tuberculosis

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Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

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The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number

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Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers

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RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo

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Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer

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Pumilio2 and Staufen2 selectively balance the synaptic proteome

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Bacterial RF3 senses chaperone function in co-translational folding

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Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress

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PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation

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Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation

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Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis

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mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis

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Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation

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In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition

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The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation

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The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans

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Translation in amino-acid-poor environments is limited by tRNAGln charging

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Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes

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ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B

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Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress

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Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity

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Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes

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The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress

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Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States

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Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression

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ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains

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RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation

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Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons

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Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development

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Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions

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Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity

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UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1

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Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway

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Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila

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Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes | American Journal of Physiology-Cell Physiology

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Redefining Single-Trial Memories in the Honeybee

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Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR

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Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC

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RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs

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Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response

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CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation

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The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma

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eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma

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On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons

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CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation

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An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development

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Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration

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Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD

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Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body

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Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons

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Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis

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RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity

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Modulation of RNA Condensation by the DEAD-Box Protein eIF4A

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Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21

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Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development

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Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer

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Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring

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Untitled document

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Interleukin‐8 enhances myocilin expression, Akt‐FoxO3 signaling and myogenic differentiation in rat skeletal muscle cells

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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome

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Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy

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mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation

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Stress Granule Assembly Disrupts Nucleocytoplasmic Transport

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Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells

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Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function

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As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid

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Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System

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Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice

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The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity

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The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

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Translational control of auditory imprinting and structural plasticity by eIF2α

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Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1

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Impaired Eukaryotic Translation Initiation Factor 2B Activity Specifically in Oligodendrocytes Reproduces the Pathology of Vanishing White Matter Disease in Mice

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