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    Microglial-derived C1q integrates into neuronal ribonucleoprotein complexes and impacts protein homeostasis in the aging brain
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    sciencedirect.com/science/article/pii/S0092867424006391
  3. Jul 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    ncbi.nlm.nih.gov/pmc/articles/PMC6895427/
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    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
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    cell.com/cell/abstract/S0092-8674(24)00693-7
  6. Jun 2024
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    eIF4F complex dynamics are important for the activation of the integrated stress response
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    ncbi.nlm.nih.gov/pmc/articles/PMC11189614/
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    Nucleolar Localization of the RNA Helicase DDX21 Predicts Survival Outcomes in Gynecologic Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11172406/
  9. May 2024
  10. 52.53.155.43 52.53.155.43
    Centriolar satellites are sites of translation of centrosomal and ciliary proteins
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    52.53.155.43/b4facf67b457be9515b769549e8e513b0c45add0/2024.02.22.581531v1.full-html.html
  11. Apr 2024
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    Thbs1 regulates skeletal muscle mass in a TGFβ-Smad2/3-ATF4-dependent manner
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    sciencedirect.com/science/article/pii/S2211124724004777
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    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  14. Mar 2024
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    Xrp1 governs the stress response program to spliceosome dysfunction
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    1. scibot 23 Mar 2024
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      DOI: 10.1093/nar/gkae055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10954486/
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    RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S2589004224005480
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    PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA
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    sciencedirect.com/science/article/pii/S2589004224005248
  18. Feb 2024
  19. www.sciencedirect.com www.sciencedirect.com
    Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation
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    1. scibot 18 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001104
  20. Jan 2024
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    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
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    ncbi.nlm.nih.gov/pmc/articles/PMC10772350/
  23. Dec 2023
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
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    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
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  26. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
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  27. Nov 2023
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    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
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    sciencedirect.com/science/article/pii/S1097276523008481
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    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
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    1. scibot 17 Nov 2023
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      DOI: 10.1126/sciadv.adf7997

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  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
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      DOI: 10.1126/sciadv.adf7997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637751/
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    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
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    sciencedirect.com/science/article/pii/S2211124723013931
  32. Oct 2023
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    ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
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  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis is differentially modulated by inhibition of translation initiation or elongation
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      DOI: 10.7554/eLife.76465

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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    sciencedirect.com/science/article/pii/S1097276521001775
  36. Sep 2023
  37. www.nature.com www.nature.com
    A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
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      DOI: 10.1038/s41467-023-40798-6

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    nature.com/articles/s41467-023-40798-6
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    Autophagy-mediated surveillance of Rim4-mRNA interaction safeguards programmed meiotic translation
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    sciencedirect.com/science/article/pii/S2211124723010628
  39. Aug 2023
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
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    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
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  42. 52.53.155.43 52.53.155.43
    The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue
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  43. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
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  44. Jul 2023
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    Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice
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    sciencedirect.com/science/article/pii/S2211124723009129
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    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer
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    sciencedirect.com/science/article/pii/S2211124723008215
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    Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape
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    sciencedirect.com/science/article/abs/pii/S2405471223001540
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    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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      DOI: 10.1016/j.neuron.2023.06.005

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    sciencedirect.com/science/article/pii/S0896627323004658
  49. Jun 2023
  50. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
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      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  51. www.sciencedirect.com www.sciencedirect.com
    Circadian clocks are modulated by compartmentalized oscillating translation
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      DOI: 10.1016/j.cell.2023.05.045

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    sciencedirect.com/science/article/pii/S0092867423005998
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    Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”
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    sciencedirect.com/science/article/pii/S2211124723006435
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    Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
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      DOI: 10.1016/j.isci.2023.106957

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    sciencedirect.com/science/article/pii/S2589004223010349
  54. May 2023
  55. www.sciencedirect.com www.sciencedirect.com
    Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
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    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
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  58. Apr 2023
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    Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression
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    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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    Xrp1 governs the stress response program to spliceosome dysfunction
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  62. Mar 2023
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    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
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    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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    The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation
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    Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss
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    METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2
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  70. Feb 2023
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    Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein
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    N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis
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    Aberrant phase separation and nucleolar dysfunction in rare genetic diseases
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    Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults
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  75. Jan 2023
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    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    Axonal plasticity in response to active forces generated through magnetic nano-pulling
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  80. Nov 2022
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    m6A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation
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    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
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  83. Oct 2022
  84. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities
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  86. Jul 2022
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    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
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    Neuron-specific translational control shift ensures proteostatic resilience during ER stress
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  90. Jun 2022
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    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains
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    Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals
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  95. May 2022
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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  97. Apr 2022
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    CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60
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  99. Feb 2022
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    TBK1-METTL3 axis facilitates antiviral immunity
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  101. Dec 2021
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    RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
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    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice
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    Proteostasis regulated by testis-specific ribosomal protein RPL39L maintains mouse spermatogenesis
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  106. Nov 2021
  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
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    A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP
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  115. Aug 2021
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    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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  126. Jul 2021
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    The Hippo Pathway Prevents YAP/TAZ-Driven Hypertranscription and Controls Neural Progenitor Number
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    Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides
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    Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers
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    RNA Docking and Local Translation Regulate Site-Specific Axon Remodeling In Vivo
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  132. currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com
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    Inhibition of YTHDF2 triggers proteotoxic cell death in MYC-driven breast cancer
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  134. Jun 2021
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    Pumilio2 and Staufen2 selectively balance the synaptic proteome
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    Bacterial RF3 senses chaperone function in co-translational folding
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  137. May 2021
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    Selective Translation of Cell Fate Regulators Mediates Tolerance to Broad Oncogenic Stress
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    PQBP1 promotes translational elongation and regulates hippocampal mGluR-LTD by suppressing eEF2 phosphorylation
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    Axon-enriched lincRNA ALAE is required for axon elongation via regulation of local mRNA translation
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    Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
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    Bicuculline regulated protein synthesis is dependent on homer1 and promotes its interaction with eEF2K through mTORC1 dependent phosphorylation
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    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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  147. Jan 2021
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    The Integrated UPR and ERAD in Oligodendrocytes Maintain Myelin Thickness in Adults by Regulating Myelin Protein Translation
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  149. Dec 2020
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The ribosomal RNA m5C methyltransferase NSUN-1 modulates healthspan and oogenesis in Caenorhabditis elegans
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    Translation in amino-acid-poor environments is limited by tRNAGln charging
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    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes
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  153. Nov 2020
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    ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B
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    Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress
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  156. Sep 2020
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    Partial Inhibition of RNA Polymerase I Promotes Animal Health and Longevity
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    Elongation inhibitors do not prevent the release of puromycylated nascent polypeptide chains from ribosomes
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    The Diabetes Gene JAZF1 Is Essential for the Homeostatic Control of Ribosome Biogenesis and Function in Metabolic Stress
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    Molecular Transducers of Human Skeletal Muscle Remodeling under Different Loading States
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    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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    ZAKα Recognizes Stalled Ribosomes through Partially Redundant Sensor Domains
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    RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
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    Late Endosomes Act as mRNA Translation Platforms and Sustain Mitochondria in Axons
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    Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
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    Autism-Misregulated eIF4G Microexons Control Synaptic Translation and Higher Order Cognitive Functions
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    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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    UBAP2L Forms Distinct Cores that Act in Nucleating Stress Granules Upstream of G3BP1
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    Regulation of stem cell function and neuronal differentiation by HERV-K via mTOR pathway
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    Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila
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    Electrical stimulation prevents doxorubicin-induced atrophy and mitochondrial loss in cultured myotubes | American Journal of Physiology-Cell Physiology
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    Redefining Single-Trial Memories in the Honeybee
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    Rheb1-Independent Activation of mTORC1 in Mammary Tumors Occurs through Activating Mutations in mTOR
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    Early Scanning of Nascent Polypeptides inside the Ribosomal Tunnel by NAC
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    RNase L Reprograms Translation by Widespread mRNA Turnover Escaped by Antiviral mRNAs
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    Concerted 2-5A-Mediated mRNA Decay and Transcription Reprogram Protein Synthesis in the dsRNA Response
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    CUL3 Deficiency Causes Social Deficits and Anxiety-like Behaviors by Impairing Excitation-Inhibition Balance through the Promotion of Cap-Dependent Translation
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    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
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    eIF4A supports an oncogenic translation program in pancreatic ductal adenocarcinoma
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    On-Site Ribosome Remodeling by Locally Synthesized Ribosomal Proteins in Axons
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    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development
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    Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
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    Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
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    Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body
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    Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons
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    Antiviral Immune Response as a Trigger of FUS Proteinopathy in Amyotrophic Lateral Sclerosis
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    RIPK3 Activation Leads to Cytokine Synthesis that Continues after Loss of Cell Membrane Integrity
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    Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
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    Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21
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    Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring
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    Interleukin‐8 enhances myocilin expression, Akt‐FoxO3 signaling and myogenic differentiation in rat skeletal muscle cells
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  200. Nov 2018
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    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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    Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome
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    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
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    mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation
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    Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
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    Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function
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    Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice
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  218. Nov 2017
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    The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity
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    Impaired Eukaryotic Translation Initiation Factor 2B Activity Specifically in Oligodendrocytes Reproduces the Pathology of Vanishing White Matter Disease in Mice
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