176 Matching Annotations
  1. Apr 2024
  2. www.sciencedirect.com www.sciencedirect.com
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
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    sciencedirect.com/science/article/pii/S221112472400384X
  3. Mar 2024
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Xrp1 governs the stress response program to spliceosome dysfunction
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    1. scibot 23 Mar 2024
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      DOI: 10.1093/nar/gkae055

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    ncbi.nlm.nih.gov/pmc/articles/PMC10954486/
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    RNA modification-related genes illuminate prognostic signature and mechanism in esophageal squamous cell carcinoma
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    1. scibot 08 Mar 2024
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    sciencedirect.com/science/article/pii/S2589004224005480
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    PABPC1 mediates degradation of C9orf72-FTLD/ALS GGGGCC repeat RNA
    1
    1. scibot 07 Mar 2024
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      DOI: 10.1016/j.isci.2024.109303

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    sciencedirect.com/science/article/pii/S2589004224005248
  7. Feb 2024
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    Unraveling the interplay between PKA inhibition and Cdk1 activation during oocyte meiotic maturation
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    1. scibot 18 Feb 2024
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    sciencedirect.com/science/article/pii/S2211124724001104
  9. Jan 2024
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    Direct neuronal reprogramming of NDUFS4 patient cells identifies the unfolded protein response as a novel general reprogramming hurdle
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    1. scibot 25 Jan 2024
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      DOI: 10.1016/j.neuron.2023.12.020

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    sciencedirect.com/science/article/pii/S0896627323009789
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FK506 bypasses the effect of erythroferrone in cancer cachexia skeletal muscle atrophy
    1
    1. scibot 12 Jan 2024
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      DOI: 10.1016/j.xcrm.2023.101306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10772350/
  12. Dec 2023
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apolipoprotein E2 Stimulates Protein Synthesis and Promotes Melanoma Progression
    1
    1. scibot 28 Dec 2023
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      DOI: 10.1158/0008-5472.CAN-23-1252

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    ncbi.nlm.nih.gov/pmc/articles/PMC10740391/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Master transcription factor reprograming unleashes selective translation promoting castration resistance and immune evasion in lethal prostate cancer.
    1
    1. scibot 15 Dec 2023
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      DOI: 10.1158/2159-8290.CD-23-0306

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    ncbi.nlm.nih.gov/pmc/articles/PMC10714140/
  15. 52.53.155.43 52.53.155.43
    cd-23-0306-html.html
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  16. Nov 2023
  17. www.sciencedirect.com www.sciencedirect.com
    K6-linked ubiquitylation marks formaldehyde-induced RNA-protein crosslinks for resolution
    1
    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S1097276523008481
  18. www.science.org www.science.org
    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
    1
    1. scibot 17 Nov 2023
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      DOI: 10.1126/sciadv.adf7997

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    science.org/doi/10.1126/sciadv.adf7997
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CLIP-Seq analysis enables the design of protective ribosomal RNA bait oligonucleotides against C9ORF72 ALS/FTD poly-GR pathophysiology
    1
    1. scibot 15 Nov 2023
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      DOI: 10.1126/sciadv.adf7997

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    ncbi.nlm.nih.gov/pmc/articles/PMC10637751/
  20. www.sciencedirect.com www.sciencedirect.com
    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1016/j.celrep.2023.113381

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    sciencedirect.com/science/article/pii/S2211124723013931
  21. Oct 2023
  22. www.sciencedirect.com www.sciencedirect.com
    ZNF692 organizes a hub specialized in 40S ribosomal subunit maturation enhancing translation in rapidly proliferating cells
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113280

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    sciencedirect.com/science/article/pii/S2211124723012925
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteostasis is differentially modulated by inhibition of translation initiation or elongation
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    1. scibot 20 Oct 2023
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      DOI: 10.7554/eLife.76465

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    ncbi.nlm.nih.gov/pmc/articles/PMC10581687/
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    mTORC1 stimulates cell growth through SAM synthesis and m6A mRNA-dependent control of protein synthesis
    1
    1. scibot 05 Oct 2023
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      DOI: 10.1016/j.molcel.2021.03.009

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    sciencedirect.com/science/article/pii/S1097276521001775
  25. Sep 2023
  26. www.nature.com www.nature.com
    A super-enhancer-regulated RNA-binding protein cascade drives pancreatic cancer
    1
    1. scibot 08 Sep 2023
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      DOI: 10.1038/s41467-023-40798-6

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    nature.com/articles/s41467-023-40798-6
  27. www.sciencedirect.com www.sciencedirect.com
    Autophagy-mediated surveillance of Rim4-mRNA interaction safeguards programmed meiotic translation
    1
    1. scibot 07 Sep 2023
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      DOI: 10.1016/j.celrep.2023.113051

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    sciencedirect.com/science/article/pii/S2211124723010628
  28. Aug 2023
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autophagy ablation in skeletal muscles worsens sepsis-induced muscle wasting, impairs whole-body metabolism, and decreases survival.
    1
    1. scibot 19 Aug 2023
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      DOI: 10.1016/j.isci.2023.107475

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    ncbi.nlm.nih.gov/pmc/articles/PMC10425945/
  30. www.sciencedirect.com www.sciencedirect.com
    FoxM1 coordinates cell division, protein synthesis, and mitochondrial activity in a subset of β cells during acute metabolic stress
    1
    1. scibot 18 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112986

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    sciencedirect.com/science/article/pii/S221112472300997X
  31. 52.53.155.43 52.53.155.43
    The miR-23-27-24 clusters drive lipid-associated macrophage proliferation in obese adipose tissue
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    1. scibot 12 Aug 2023
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      DOI: 10.1016/j.celrep.2023.112928

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      DOI: 10.1016/j.celrep.2023.112928

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    52.53.155.43/4a6b7aa5507bdf2becad8c264c3514e078fa27b5/PIIS2211124723009397-html.html
  32. 52.53.155.43 52.53.155.43
    can-23-1252-html.html
    1
    1. scibot 11 Aug 2023
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      DOI: 10.1158/0008-5472.CAN-23-1252

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  33. Jul 2023
  34. www.sciencedirect.com www.sciencedirect.com
    Cell-type-specific disruption of cortico-striatal circuitry drives repetitive patterns of behavior in fragile X syndrome model mice
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      DOI: 10.1016/j.celrep.2023.112901

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    sciencedirect.com/science/article/pii/S2211124723009129
  35. www.sciencedirect.com www.sciencedirect.com
    NAT10-mediated ac4C tRNA modification promotes EGFR mRNA translation and gefitinib resistance in cancer
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    1. scibot 21 Jul 2023
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      DOI: 10.1016/j.celrep.2023.112810

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    sciencedirect.com/science/article/pii/S2211124723008215
  36. www.sciencedirect.com www.sciencedirect.com
    Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape
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      DOI: 10.1016/j.cels.2023.06.001

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    sciencedirect.com/science/article/abs/pii/S2405471223001540
  37. www.sciencedirect.com www.sciencedirect.com
    Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration
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    1. scibot 13 Jul 2023
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      DOI: 10.1016/j.neuron.2023.06.005

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    sciencedirect.com/science/article/pii/S0896627323004658
  38. Jun 2023
  39. www.sciencedirect.com www.sciencedirect.com
    QKI shuttles internal m7G-modified transcripts into stress granules and modulates mRNA metabolism
    1
    1. scibot 28 Jun 2023
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      DOI: 10.1016/j.cell.2023.05.047

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    sciencedirect.com/science/article/pii/S0092867423005986
  40. www.sciencedirect.com www.sciencedirect.com
    Circadian clocks are modulated by compartmentalized oscillating translation
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      DOI: 10.1016/j.cell.2023.05.045

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    sciencedirect.com/science/article/pii/S0092867423005998
  41. www.sciencedirect.com www.sciencedirect.com
    Nuclear translocation of an aminoacyl-tRNA synthetase may mediate a chronic “integrated stress response”
    1
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      DOI: 10.1016/j.celrep.2023.112632

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    sciencedirect.com/science/article/pii/S2211124723006435
  42. www.sciencedirect.com www.sciencedirect.com
    Differential toxicity and localization of arginine-rich C9ORF72 dipeptide repeat proteins depend on de-clustering of positive charges.
    1
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      DOI: 10.1016/j.isci.2023.106957

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    sciencedirect.com/science/article/pii/S2589004223010349
  43. May 2023
  44. www.sciencedirect.com www.sciencedirect.com
    Systematic identification of anticancer drug targets reveals a nucleus-to-mitochondria ROS-sensing pathway
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      DOI: 10.1016/j.cell.2023.04.026

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    sciencedirect.com/science/article/pii/S0092867423004221
  45. www.nature.com www.nature.com
    Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance
    1
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      DOI: 10.1038/s41467-022-31905-0

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    nature.com/articles/s41467-022-31905-0
  46. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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      DOI: 10.1002/1878-0261.13434

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    febs.onlinelibrary.wiley.com/doi/full/10.1002/1878-0261.13434
  47. Apr 2023
  48. www.sciencedirect.com www.sciencedirect.com
    Transcriptional-translational conflict is a barrier to cellular transformation and cancer progression
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      DOI: 10.1016/j.ccell.2023.03.021

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    sciencedirect.com/science/article/pii/S1535610823000946
  49. europepmc.org europepmc.org
    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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      DOI: 10.1016/j.isci.2023.106526

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    europepmc.org/article/pmc/pmc10105291
  50. www.biorxiv.org www.biorxiv.org
    Xrp1 governs the stress response program to spliceosome dysfunction
    1
    1. scibot 20 Apr 2023
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      DOI: 10.1101/2023.04.06.535851

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    biorxiv.org/content/10.1101/2023.04.06.535851v1
  51. Mar 2023
  52. www.sciencedirect.com www.sciencedirect.com
    Ribosome-rescuer PELO catalyzes the oligomeric assembly of NOD-like receptor family proteins via activating their ATPase enzymatic activity
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      DOI: 10.1016/j.immuni.2023.02.014

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    sciencedirect.com/science/article/pii/S1074761323000882
  53. 52.53.155.43 52.53.155.43
    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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      DOI: 10.1152/ajpcell.00025.2022

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  54. journals.physiology.org journals.physiology.org
    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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    Remodeling of the Ribosomal Quality Control and Protein Translation by a Viral Ubiquitin Deconjugase
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    The proteome and transcriptome of stress granules and P bodies during human T lymphocyte activation
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    Activation of β-catenin in mesenchymal progenitors leads to muscle mass loss
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    METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2
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  59. Feb 2023
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    Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein
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    N6-methyladenosine modification in 18S rRNA promotes tumorigenesis and chemoresistance via HSF4b/HSP90B1/mutant p53 axis
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    Aberrant phase separation and nucleolar dysfunction in rare genetic diseases
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    Endoplasmic reticulum associated degradation is essential for maintaining the viability or function of mature myelinating cells in adults
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  64. Jan 2023
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    Protein folding stress potentiates NLRP1 and CARD8 inflammasome activation
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    Targeting BCAT1 combined with α-ketoglutarate triggers metabolic synthetic lethality in glioblastoma
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    METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism
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    Axonal plasticity in response to active forces generated through magnetic nano-pulling
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  69. Nov 2022
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    m6A-modified lincRNA Dubr is required for neuronal development by stabilizing YTHDF1/3 and facilitating mRNA translation
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    Ribosome stalling is a signal for metabolic regulation by the ribotoxic stress response
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  72. Oct 2022
  73. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities
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  75. Jul 2022
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    Slc12a8 in the lateral hypothalamus maintains energy metabolism and skeletal muscle functions during aging
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    GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment
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    Neuron-specific translational control shift ensures proteostatic resilience during ER stress
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  79. Jun 2022
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    Sensitization of FOLFOX-resistant colorectal cancer cells via the modulation of a novel pathway involving protein phosphatase 2A
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    pSNAP: Proteome-wide analysis of elongating nascent polypeptide chains
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    Presynaptic FMRP and local protein synthesis support structural and functional plasticity of glutamatergic axon terminals
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  84. May 2022
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    Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes
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  86. Apr 2022
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    CLOCK regulates Drp1 mRNA stability and mitochondrial homeostasis by interacting with PUF60
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  88. Feb 2022
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  90. Dec 2021
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    RhoA within myofibers controls satellite cell microenvironment to allow hypertrophic growth
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    Aging Does Not Exacerbate Muscle Loss During Denervation and Lends Unique Muscle-Specific Atrophy Resistance With Akt Activation
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    Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice
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  95. Nov 2021
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    Control of protein synthesis and memory by GluN3A-NMDA receptors through inhibition of GIT1/mTORC1 assembly
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    mTOR-dependent translation drives tumor infiltrating CD8+ effector and CD4+ Treg cells expansion
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    RNA-binding protein FXR1 drives cMYC translation by recruiting eIF4F complex to the translation start site
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  99. Sep 2021
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    The oncomicropeptide APPLE promotes hematopoietic malignancy by enhancing translation initiation
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    Increased fidelity of protein synthesis extends lifespan
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    Diurnal regulation of oxidative phosphorylation restricts hepatocyte proliferation and inflammation
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    A photoaffinity labeling strategy identified EF1A1 as a binding protein of cyclic dinucleotide 2′3′-cGAMP
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  104. Aug 2021
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    Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy
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    Cell-type-specific profiling of human cellular models of fragile X syndrome reveal PI3K-dependent defects in translation and neurogenesis
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    Unbiased Proteomic Screening Identifies a Novel Role for the E3 Ubiquitin Ligase Nedd4‐2 in Translational Suppression During ER Stress
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    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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    RNA-Induced Conformational Switching and Clustering of G3BP Drive Stress Granule Assembly by Condensation
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    Non-Canonical Caspase Activity Antagonizes p38 MAPK Stress-Priming Function to Support Development
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    Nucleocytoplasmic Proteomic Analysis Uncovers eRF1 and Nonsense-Mediated Decay as Modifiers of ALS/FTD C9orf72 Toxicity
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    Inter-dependent Centrosomal Co-localization of the cen and ik2 cis-Natural Antisense mRNAs in Drosophila
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    The X-Linked DDX3X RNA Helicase Dictates Translation Reprogramming and Metastasis in Melanoma
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    CRISPR-Cas9 Screens Identify the RNA Helicase DDX3X as a Repressor of C9ORF72 (GGGGCC)n Repeat-Associated Non-AUG Translation
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    An ECM-to-Nucleus Signaling Pathway Activates Lysosomes for C. elegans Larval Development
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    Astrocyte Unfolded Protein Response Induces a Specific Reactivity State that Causes Non-Cell-Autonomous Neuronal Degeneration
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    Small-Molecule Modulation of TDP-43 Recruitment to Stress Granules Prevents Persistent TDP-43 Accumulation in ALS/FTD
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    Pum2 Shapes the Transcriptome in Developing Axons through Retention of Target mRNAs in the Cell Body
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    Sam68 Enables Metabotropic Glutamate Receptor-Dependent LTD in Distal Dendritic Regions of CA1 Hippocampal Neurons
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    Modulation of RNA Condensation by the DEAD-Box Protein eIF4A
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    Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21
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    Modulating eIF6 levels unveils the role of translation in ecdysone biosynthesis during Drosophila development
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    Functional Redundancy between β1 and β3 Integrin in Activating the IR/Akt/mTORC1 Signaling Axis to Promote ErbB2-Driven Breast Cancer
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    Noncanonical Modulation of the eIF2 Pathway Controls an Increase in Local Translation during Neural Wiring
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    Interleukin‐8 enhances myocilin expression, Akt‐FoxO3 signaling and myogenic differentiation in rat skeletal muscle cells
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    Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells
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    Rapid Cue-Specific Remodeling of the Nascent Axonal Proteome
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    Ubiquitination of ABCE1 by NOT4 in Response to Mitochondrial Damage Links Co-translational Quality Control to PINK1-Directed Mitophagy
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    mTORC1 Is Transiently Reactivated in Injured Nerves to Promote c-Jun Elevation and Schwann Cell Dedifferentiation
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  196. www.sciencedirect.com www.sciencedirect.com
    Stress Granule Assembly Disrupts Nucleocytoplasmic Transport
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    Pseudouridylation of tRNA-Derived Fragments Steers Translational Control in Stem Cells
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  198. europepmc.org europepmc.org
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Axon-Axon Interactions Regulate Topographic Optic Tract Sorting via CYFIP2-Dependent WAVE Complex Function
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    As Extracellular Glutamine Levels Decline, Asparagine Becomes an Essential Amino Acid
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    Epitranscriptomic m6A Regulation of Axon Regeneration in the Adult Mammalian Nervous System
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    Nuclear localization of EIF4G3 suggests a role for the XY body in translational regulation during spermatogenesis in mice
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  206. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  207. Nov 2017
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    The Mammalian Ribo-interactome Reveals Ribosome Functional Diversity and Heterogeneity
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  209. elifesciences.org elifesciences.org
    The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration
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    Translational control of auditory imprinting and structural plasticity by eIF2α
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    Hermes Regulates Axon Sorting in the Optic Tract by Post-Trancriptional Regulation of Neuropilin 1
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    Impaired Eukaryotic Translation Initiation Factor 2B Activity Specifically in Oligodendrocytes Reproduces the Pathology of Vanishing White Matter Disease in Mice
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      primary antibody against puromycin

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