1,711 Matching Annotations
  1. Nov 2023
  2. www.sciencedirect.com www.sciencedirect.com
    The bone transcription factor Osterix controls extracellular matrix- and node of Ranvier-related gene expression in oligodendrocytes
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    1. scibot 10 Nov 2023
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    sciencedirect.com/science/article/pii/S089662732300764X
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    Autophagy-mediated control of ribosome homeostasis in oncogene-induced senescence
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      DOI: 10.1016/j.celrep.2023.113381

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    sciencedirect.com/science/article/pii/S2211124723013931
  4. 52.53.155.43 52.53.155.43
    mvad090-html.html
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    1. scibot 10 Nov 2023
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    52.53.155.43/c37b54a85bb2ab75b40e99c8cb130778e791e084/mvad090-html.html
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repression of CENP-A assembly in metaphase requires HJURP phosphorylation and inhibition by M18BP1
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    1. scibot 09 Nov 2023
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      DOI: 10.1083/jcb.202110124

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    ncbi.nlm.nih.gov/pmc/articles/PMC10165474/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10617673/
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    Gadd45β is critical for regulation of type I interferon signaling by facilitating G3BP-mediated stress granule formation
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    sciencedirect.com/science/article/pii/S2211124723013700
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    V-ATPase recruitment to ER exit sites switches COPII-mediated transport to lysosomal degradation
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    sciencedirect.com/science/article/pii/S1534580723005269
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    Blue light receptor CRY1 regulates HSFA1d nuclear localization to promote plant thermotolerance
    1
    1. scibot 03 Nov 2023
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    sciencedirect.com/science/article/pii/S2211124723011294
  10. 52.53.155.43 52.53.155.43
    s11684-022-0959-5 (1)-html.html
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      DOI: 10.3389/fncel.2020.552213

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  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hepatic conversion of acetyl-CoA to acetate plays crucial roles in energy stress
    1
    1. scibot 02 Nov 2023
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      DOI: 10.7554/eLife.87419

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    ncbi.nlm.nih.gov/pmc/articles/PMC10615369/
  12. Oct 2023
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    MiniBAR/GARRE1 is a dual Rac and Rab effector required for ciliogenesis
    1
    1. scibot 28 Oct 2023
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    sciencedirect.com/science/article/pii/S1534580723005129
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    Lactate activates the mitochondrial electron transport chain independently of its metabolism
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    1. scibot 28 Oct 2023
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    sciencedirect.com/science/article/pii/S1097276523008006
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    PRMT5 mediates FoxO1 methylation and subcellular localization to regulate lipophagy in myogenic progenitors
    1
    1. scibot 28 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723013414
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    Dual agonistic and antagonistic roles of ZC3H18 provide for co-activation of distinct nuclear RNA decay pathways
    1
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    sciencedirect.com/science/article/pii/S2211124723013372
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    Tyrosine catabolism enhances genotoxic chemotherapy by suppressing translesion DNA synthesis in epithelial ovarian cancer
    1
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    sciencedirect.com/science/article/pii/S1550413123003716
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    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    sciencedirect.com/science/article/pii/S1097276523007554
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    The histone chaperone ANP32B regulates chromatin incorporation of the atypical human histone variant macroH2A
    1
    1. scibot 27 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723013128
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    Mouse models of human CNTNAP1-associated congenital hypomyelinating neuropathy and genetic restoration of murine neurological deficits
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113274

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    sciencedirect.com/science/article/pii/S221112472301286X
  21. 52.53.155.43 52.53.155.43
    mvad079-html.html
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    1. scibot 21 Oct 2023
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    52.53.155.43/8abf34a7759ef6c4994c44258c9102a29e041757/mvad079-html.html
  22. www.science.org www.science.org
    The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/science.adh5021

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    science.org/doi/10.1126/science.adh5021
  23. onlinelibrary.wiley.com onlinelibrary.wiley.com
    STAT3 modulates CD4+ T mitochondrial dynamics and function in aging
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    onlinelibrary.wiley.com/doi/10.1111/acel.13996
  24. www.biorxiv.org www.biorxiv.org
    Molecular model of a bacterial flagellar motor in situ reveals a “parts-list” of protein adaptations to increase torque
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1101/2023.09.08.556779

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    biorxiv.org/content/10.1101/2023.09.08.556779v1
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    An integrative approach unveils a distal encounter site for rPTPε and phospho-Src complex formation
    1
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      DOI: 10.1016/j.str.2023.09.004

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    sciencedirect.com/science/article/abs/pii/S0969212623003295
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    Structural and biochemical insights into the interaction mechanism underlying HORMAD1 and its partner proteins
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    sciencedirect.com/science/article/abs/pii/S0969212623003271
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    Peroxisomal ERK mediates Akh/glucagon action and glycemic control
    1
    1. scibot 14 Oct 2023
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    sciencedirect.com/science/article/pii/S2211124723012123
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    ADAR1p150 prevents MDA5 and PKR activation via distinct mechanisms to avert fatal autoinflammation
    1
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    sciencedirect.com/science/article/abs/pii/S1097276523007402
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    Universal features of Nsp1-mediated translational shutdown by coronaviruses
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    sciencedirect.com/science/article/abs/pii/S1097276523006974
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    Species-specific FMRP regulation of RACK1 is critical for prenatal cortical development
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      DOI: 10.1016/j.neuron.2023.09.014

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    Melanocortin-3 receptor expression in AgRP neurons is required for normal activation of the neurons in response to energy deficiency
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    sciencedirect.com/science/article/pii/S2211124723012007
  32. www.cell.com www.cell.com
    Dominant-negative HNF1α mutant promotes liver steatosis and inflammation by regulating hepatic complement factor D
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    cell.com/iscience/abstract/S2589-0042(23)02095-3
  33. www.cell.com www.cell.com
    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
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    cell.com/iscience/abstract/S2589-0042(23)02074-6
  34. www.cell.com www.cell.com
    AMER1 deficiency promotes the distant metastasis of colorectal cancer by inhibiting SLC7A11- and FTL-mediated ferroptosis
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    cell.com/cell-reports/abstract/S2211-1247(23)01121-X
  35. www.cell.com www.cell.com
    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
    1
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    cell.com/cell-reports/abstract/S2211-1247(23)01110-5
  36. www.cell.com www.cell.com
    The heat shock protein Hsp27 controls mitochondrial function by modulating ceramide generation
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    cell.com/cell-reports/abstract/S2211-1247(23)01092-6
  37. www.cell.com www.cell.com
    Methylation of KRAS by SETD7 promotes KRAS degradation in non-small cell lung cancer
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    cell.com/cell-reports/abstract/S2211-1247(23)01014-8
  38. 52.53.155.43 52.53.155.43
    PIIS2211124723012159-html.html
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    Unannotated microprotein EMBOW regulates the interactome and chromatin and mitotic functions of WDR5
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      DOI: 10.1016/j.celrep.2023.113145

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    sciencedirect.com/science/article/pii/S2211124723011579
  40. Sep 2023
  41. www.sciencedirect.com www.sciencedirect.com
    Apical polarity and actomyosin dynamics control Kibra subcellular localization and function in Drosophila Hippo signaling
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    Principles of assembly and regulation of condensates of Polycomb repressive complex 1 through phase separation
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    RANK ligand converts the NCoR/HDAC3 co-repressor to a PGC1β- and RNA-dependent co-activator of osteoclast gene expression
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    Identifying G protein-coupled receptors involved in adipose tissue function using the innovative RNA-seq database FATTLAS
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    Single-cell multi-omics defines the cell-type-specific impact of splicing aberrations in human hematopoietic clonal outgrowths
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    Chemoproteomic strategy identified p120-catenin glutathionylation regulates E-cadherin degradation and cell migration
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    Direct recruitment of Mis18 to interphase spindle pole bodies promotes CENP-A chromatin assembly
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    MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy
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    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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    CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis
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    Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10
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    A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis
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    CHCHD2 Thr61Ile mutation impairs F1F0-ATPase assembly in in vitro and in vivo models of Parkinson’s disease
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    Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells
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    Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions
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    Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability
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    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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    E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response
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    LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis
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    Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis
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    Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis
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    Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ
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    Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine
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    Phosphatidylinositol 3-phosphate regulates iron transport via PI3P-binding CgPil1 protein
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    Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover
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    Banana MKK1 modulates fruit ripening via the MKK1-MPK6-3/11-4-bZIP21 module
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    Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein
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    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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    Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions
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    Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome
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    Apical polarity and actomyosin dynamics regulate Hippo signaling by controlling Kibra subcellular localization
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    Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice
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    The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER
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    Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
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    Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells
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    Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40
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    Convergence of multiple RNA-silencing pathways on GW182/TNRC6
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    Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis
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    A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity
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    Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer
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    Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition
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    Enterohemorrhagic Escherichia coli senses microbiota-derived nicotinamide to increase its virulence and colonization in the large intestine
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    Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification
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    A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer
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  134. May 2023
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    IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance
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    RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity
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    A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma
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    Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
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    PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway
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    Glutamate-releasing BEST1 channel is a new target for neuroprotection against ischemic stroke with wide time window
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    The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy
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    Methylated histones on mitotic chromosomes promote Topoisomerase IIα function for high fidelity chromosome segregation.
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells
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    Organism-wide, cell-type-specific secretome mapping of exercise training in mice
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    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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    UTP18-mediated p21 mRNA instability drives adenoma-carcinoma progression in colorectal cancer
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    Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals
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    Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue
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    Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors
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    The mechanism of STING autoinhibition and activation
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    Gαs slow conformational transition upon GTP binding and a novel Gαs regulator
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    Proteomic discovery of chemical probes that perturb protein complexes in human cells
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    Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut
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    Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication
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    A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans
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    ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer
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    Ecdysone signaling determines lateral polarity and remodels neurites to form Drosophila’s left-right brain asymmetry
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    X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species
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    Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens
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    PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection
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    SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology
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    Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis
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    The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells
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    Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes
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    Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation
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    Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii
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    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation
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    An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay
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    Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS
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    Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence
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    The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus
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    A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in C. elegans
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    Structural basis for the Rad6 activation by the Bre1 N-terminal domain
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    Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice
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    The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells
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    A combinatorial approach to uncover an additional Integrator subunit
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