711 Matching Annotations
  1. Nov 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Profiling lariat intermediates reveals genetic determinants of early and late co-transcriptional splicing
    1
    1. scibot 29 Nov 2022
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      DOI: 10.1016/j.molcel.2022.11.004

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    sciencedirect.com/science/article/pii/S1097276522010668
  3. onlinelibrary.wiley.com onlinelibrary.wiley.com
    LncRNA nuclear-enriched abundant transcript 1 aggravates cerebral ischemia/reperfusion injury through activating early growth response-1/RNA binding motif protein 25 axis
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    1. scibot 22 Nov 2022
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      DOI: 10.1111/jnc.15692

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15692
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    Pan-claudin family interactome analysis reveals shared and specific interactions
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1016/j.celrep.2022.111588

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    sciencedirect.com/science/article/pii/S221112472201453X
  5. 52.53.155.43 52.53.155.43
    Loss of the Ash2l subunit of histone H3K4 methyltransferase complexes promotes chromatin compaction at promoters
    1
    1. scibot 03 Nov 2022
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      DOI: 10.21203/rs.3.rs-1992778/v1

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    52.53.155.43/2bd54e9365bad522cb4a8b476de43c7b8e5f1883/33e3335b-b6e5-4d66-a51d-edb70848662b-html.html
  6. www.sciencedirect.com www.sciencedirect.com
    Integrator endonuclease drives promoter-proximal termination at all RNA polymerase II-transcribed loci
    1
    1. scibot 03 Nov 2022
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      DOI: 10.1016/j.molcel.2022.10.004

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    sciencedirect.com/science/article/pii/S1097276522009613
  7. Oct 2022
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity
    1
    1. scibot 26 Oct 2022
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      DOI: 10.1126/sciadv.abo5578

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    ncbi.nlm.nih.gov/pmc/articles/PMC9519039/
  9. www.science.org www.science.org
    The long noncoding RNA mimi scaffolds neuronal granules to maintain nervous system maturity
    1
    1. scibot 22 Oct 2022
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      DOI: 10.1126/sciadv.abo5578

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    science.org/doi/10.1126/sciadv.abo5578
  10. www.sciencedirect.com www.sciencedirect.com
    A surface-receptor-coupled G protein regulates plant immunity through nuclear protein kinases
    1
    1. scibot 14 Oct 2022
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      DOI: 10.1016/j.chom.2022.09.012

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    sciencedirect.com/science/article/pii/S1931312822004681
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sox9 mediates Autophagy-dependent vascular smooth muscle cell phenotypic modulation and transplant arteriosclerosis
    1
    1. scibot 07 Oct 2022
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      DOI: 10.1016/j.isci.2022.105161

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    ncbi.nlm.nih.gov/pmc/articles/PMC9531173/
  12. www.sciencedirect.com www.sciencedirect.com
    p300/CBP sustains Polycomb silencing by non-enzymatic functions
    1
    1. scibot 07 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.005

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    sciencedirect.com/science/article/pii/S1097276522008942
  13. www.nature.com www.nature.com
    Regulation of KDM5C stability and enhancer reprogramming in breast cancer
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1038/s41419-022-05296-5

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    nature.com/articles/s41419-022-05296-5
  14. www.sciencedirect.com www.sciencedirect.com
    Chromatin jets define the properties of cohesin-driven in vivo loop extrusion
    1
    1. scibot 05 Oct 2022
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      DOI: 10.1016/j.molcel.2022.09.003

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    sciencedirect.com/science/article/pii/S1097276522008541
  15. Sep 2022
  16. www.sciencedirect.com www.sciencedirect.com
    A nuclear cAMP microdomain suppresses tumor growth by Hippo pathway inactivation
    1
    1. scibot 29 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111412

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    sciencedirect.com/science/article/pii/S2211124722012530
  17. www.sciencedirect.com www.sciencedirect.com
    Immune chromatin reader SP140 regulates microbiota and risk for inflammatory bowel disease
    1
    1. scibot 22 Sep 2022
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      DOI: 10.1016/j.chom.2022.08.018

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    sciencedirect.com/science/article/pii/S1931312822004176
  18. www.sciencedirect.com www.sciencedirect.com
    SMN controls neuromuscular junction integrity through U7 snRNP
    1
    1. scibot 21 Sep 2022
      RRID:AB_302613

      DOI: 10.1016/j.celrep.2022.111393

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    sciencedirect.com/science/article/pii/S221112472201230X
  19. www.sciencedirect.com www.sciencedirect.com
    Heterologous reporter expression in the planarian Schmidtea mediterranea through somatic mRNA transfection
    1
    1. scibot 21 Sep 2022
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      DOI: 10.1016/j.crmeth.2022.100298

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    sciencedirect.com/science/article/pii/S2667237522001801
  20. www.sciencedirect.com www.sciencedirect.com
    Developmental and housekeeping transcriptional programs in Drosophila require distinct chromatin remodelers
    1
    1. scibot 16 Sep 2022
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      DOI: 10.1016/j.molcel.2022.08.019

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    sciencedirect.com/science/article/pii/S1097276522008085
  21. www.sciencedirect.com www.sciencedirect.com
    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
    1
    1. scibot 08 Sep 2022
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      DOI: 10.1016/j.celrep.2022.111315

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    sciencedirect.com/science/article/pii/S2211124722011391
  22. Aug 2022
  23. www.sciencedirect.com www.sciencedirect.com
    The Il6 -39kb enhancer containing clustered GATA2- and PU.1- binding sites is essential for Il6 expression in murine mast cells
    1
    1. scibot 31 Aug 2022
      RRID:AB_302613

      DOI: 10.1016/j.isci.2022.104942

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    sciencedirect.com/science/article/pii/S2589004222012147
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Polycomb-mediated repression of paternal chromosomes maintains haploid dosage in diploid embryos of Marchantia
    1
    1. scibot 27 Aug 2022
      RRID:AB_302613

      DOI: 10.7554/eLife.79258

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    ncbi.nlm.nih.gov/pmc/articles/PMC9402228/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AR-V7 exhibits non-canonical mechanisms of nuclear import and chromatin engagement in castrate-resistant prostate cancer
    1
    1. scibot 26 Aug 2022
      RRID:AB_302613

      DOI: 10.7554/eLife.73396

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    ncbi.nlm.nih.gov/pmc/articles/PMC9398446/
  26. www.sciencedirect.com www.sciencedirect.com
    RAD51 protects human cells from transcription-replication conflicts
    1
    1. scibot 26 Aug 2022
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      DOI: 10.1016/j.molcel.2022.07.010

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    sciencedirect.com/science/article/pii/S1097276522007067
  27. www.sciencedirect.com www.sciencedirect.com
    Molecular conflicts disrupting centromere maintenance contribute to Xenopus hybrid inviability
    1
    1. scibot 16 Aug 2022
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      DOI: 10.1016/j.cub.2022.07.037

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    sciencedirect.com/science/article/pii/S0960982222011745
  28. www.sciencedirect.com www.sciencedirect.com
    Discovery of compounds that reactivate p53 mutants in vitro and in vivo
    1
    1. scibot 12 Aug 2022
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      DOI: 10.1016/j.chembiol.2022.07.003

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    sciencedirect.com/science/article/pii/S2451945622002756
  29. www.sciencedirect.com www.sciencedirect.com
    mTORC1 is required for epigenetic silencing during β-cell functional maturation
    1
    1. scibot 10 Aug 2022
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      DOI: 10.1016/j.molmet.2022.101559

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    sciencedirect.com/science/article/pii/S2212877822001284
  30. www.sciencedirect.com www.sciencedirect.com
    Broad-spectrum chemicals block ROS detoxification to prevent plant fungal invasion
    1
    1. scibot 06 Aug 2022
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      DOI: 10.1016/j.cub.2022.07.022

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    sciencedirect.com/science/article/pii/S096098222201123X
  31. Jul 2022
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A non-transcriptional function of Yap regulates the DNA replication program in Xenopus laevis
    1
    1. scibot 31 Jul 2022
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      DOI: 10.7554/eLife.75741

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    ncbi.nlm.nih.gov/pmc/articles/PMC9328763/
  33. www.sciencedirect.com www.sciencedirect.com
    Acetylation of p62 regulates base excision repair through interaction with APE1
    1
    1. scibot 27 Jul 2022
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      DOI: 10.1016/j.celrep.2022.111116

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    sciencedirect.com/science/article/pii/S2211124722009226
  34. yc.mlpla.mil.cn yc.mlpla.mil.cn
    Temporal resolution of gene derepression and proteome changes upon PROTAC-mediated degradation of BCL11A protein in erythroid cells
    1
    1. scibot 15 Jul 2022
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      DOI: 10.1016/j.chembiol.2022.06.007

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    yc.mlpla.mil.cn/s/com/sciencedirect/www/G.https/science/article/pii/S2451945622002392
  35. academic.oup.com academic.oup.com
    Induction of senescence upon loss of the Ash2l core subunit of H3K4 methyltransferase complexes
    1
    1. scibot 13 Jul 2022
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      DOI: 10.1093/nar/gkac591

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac591/6640223
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase separation of HRLP regulates flowering time in Arabidopsis
    1
    1. scibot 09 Jul 2022
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      DOI: 10.1126/sciadv.abn5488

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    ncbi.nlm.nih.gov/pmc/articles/PMC9217094/
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    Inhibition of DYRK1A, via histone modification, promotes cardiomyocyte cell cycle activation and cardiac repair after myocardial infarction
    1
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      DOI: 10.1016/j.ebiom.2022.104139

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    sciencedirect.com/science/article/pii/S2352396422003206
  38. Jun 2022
  39. 52.53.155.43 52.53.155.43
    cd-21-1514-html.html
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      DOI: 10.1158/2159-8290.CD-21-1514

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      DOI: 10.1158/2159-8290.cd-21-1514

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      DOI: 10.1158/2159-8290.cd-21-1514

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    52.53.155.43/30b9574de57b2e4ccfd380c8f4f8e4cb5eb75f43/cd-21-1514-html.html
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    Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
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      DOI: 10.1016/j.isci.2022.104517

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    sciencedirect.com/science/article/pii/S258900422200788X
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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      DOI: 10.1016/j.chembiol.2022.05.006

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    sciencedirect.com/science/article/pii/S2451945622001982
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    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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      DOI: 10.1016/j.celrep.2022.110988

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    sciencedirect.com/science/article/pii/S2211124722007744
  43. www.sciencedirect.com www.sciencedirect.com
    Oncogenic ZMYND11-MBTD1 fusion protein anchors the NuA4/TIP60 histone acetyltransferase complex to the coding region of active genes
    1
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      DOI: 10.1016/j.celrep.2022.110947

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    sciencedirect.com/science/article/pii/S221112472200729X
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    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
    1
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      DOI: 10.1016/j.celrep.2022.110944

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    sciencedirect.com/science/article/pii/S2211124722007264
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    A rice protein modulates endoplasmic reticulum homeostasis and coordinates with a transcription factor to initiate blast disease resistance
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      DOI: 10.1016/j.celrep.2022.110941

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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
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    Breaking boundaries: Pan BETi disrupt 3D chromatin structure, BD2-selective BETi are strictly epigenetic transcriptional regulators
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    JAZF1-SUZ12 dysregulates PRC2 function and gene expression during cell differentiation
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    Oct4 differentially regulates chromatin opening and enhancer transcription in pluripotent stem cells
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  50. May 2022
  51. www.nature.com www.nature.com
    Alcohol induced increases in sperm Histone H3 lysine 4 trimethylation correlate with increased placental CTCF occupancy and altered developmental programming
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    Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1
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    Twist2-driven chromatin remodeling governs the postnatal maturation of dermal fibroblasts
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    Single-cell analysis of human testis aging and correlation with elevated body mass index
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  55. Apr 2022
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    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    Microtubules promote the non-cell autonomous action of microRNAs by inhibiting their cytoplasmic loading onto ARGONAUTE1 in Arabidopsis
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    Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks
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    CTCF functions as an insulator for somatic genes and a chromatin remodeler for pluripotency genes during reprogramming
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    PGC1α/β EXPRESSION PREDICTS THERAPEUTIC RESPONSE TO OXIDATIVE PHOSPHORYLATION INHIBITION IN OVARIAN CANCER
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  62. Mar 2022
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The TFIIH complex is required to establish and maintain mitotic chromosome structure
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    Chromatin modifier HUSH co-operates with RNA decay factor NEXT to restrict transposable element expression
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    Histone deacetylation regulates nucleotide excision repair through an interaction with the XPC protein
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    Liquid-to-solid phase transition of oskar ribonucleoprotein granules is essential for their function in Drosophila embryonic development
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    Neddylation is essential for β-catenin degradation in Wnt signaling pathway
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    FBXO47 is essential for preventing the synaptonemal complex from premature disassembly in mouse male meiosis
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    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
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    A trio of ubiquitin ligases sequentially drives ubiquitylation and autophagic degradation of dysfunctional yeast proteasomes
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    Dynamic control of chromatin-associated m6A methylation regulates nascent RNA synthesis
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    An Inducible CRISPR/Cas9 Screen Identifies DTX2 as a Transcriptional Regulator of Human Telomerase
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    dCas9 fusion to computer-designed PRC2 inhibitor reveals functional TATA box in distal promoter region
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  74. Feb 2022
  75. elifesciences.org elifesciences.org
    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
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    Ketogenic diet and chemotherapy combine to disrupt pancreatic cancer metabolism and growth
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    E3 ligase RNF167 and deubiquitinase STAMBPL1 modulate mTOR and cancer progression
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  78. Jan 2022
  79. www.cell.com www.cell.com
    Pseudouridine synthases modify human pre-mRNA co-transcriptionally and affect pre-mRNA processing
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    Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
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    Histone acetyltransferase NAA40 modulates acetyl-CoA levels and lipid synthesis
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    Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome
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  83. Dec 2021
  84. www.sciencedirect.com www.sciencedirect.com
    EMSY inhibits homologous recombination repair and the interferon response, promoting lung cancer immune evasion
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    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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    Potent macrocycle inhibitors of the human SAGA deubiquitinating module
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    Evolution of a histone variant involved in compartmental regulation of NAD metabolism
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    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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    The protease SPRTN and SUMOylation coordinate DNA-protein crosslink repair to prevent genome instability
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    Methods to separate nuclear soluble fractions reflecting localizations in living cells
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    SUMOylation of linker histone H1 drives chromatin condensation and restriction of embryonic cell fate identity
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    Sumoylation of the human histone H4 tail inhibits p300-mediated transcription by RNA polymerase II in cellular extracts
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    MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts
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    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
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    Identification of the sex-determining factor in the liverwort Marchantia polymorpha reveals unique evolution of sex chromosomes in a haploid system
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    A complex of BRCA2 and PP2A-B56 is required for DNA repair by homologous recombination
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    The BORDER family of negative transcription elongation factors regulates flowering time in Arabidopsis
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    A viral histone-like protein exploits antagonism between linker histones and HMGB proteins to obstruct the cell cycle
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    PIWI-mediated control of tissue-specific transposons is essential for somatic cell differentiation
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    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
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    A hydride transfer complex reprograms NAD metabolism and bypasses senescence
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    DOT1L O-GlcNAcylation promotes its protein stability and MLL-fusion leukemia cell proliferation
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    The prolyl-isomerase PIN1 is essential for nuclear Lamin-B structure and function and protects heterochromatin under mechanical stress
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    Splicing modulators elicit global translational repression by condensate-prone proteins translated from introns
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    Linker histone H1.8 inhibits chromatin binding of condensins and DNA topoisomerase II to tune chromosome length and individualization
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    Reshaping of the androgen-driven chromatin landscape in normal prostate cells by early cancer drivers and effect on therapeutic sensitivity
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    UV-induced reduction in Polycomb repression promotes epidermal pigmentation
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    Mutant U2AF1-induced alternative splicing of H2afy (macroH2A1) regulates B-lymphopoiesis in mice
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    Epigenetic Dysregulation Induces Translocation of Histone H3 into Cytoplasm
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    miR-1 coordinately regulates lysosomal v-ATPase and biogenesis to impact proteotoxicity and muscle function during aging
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    DNA Damage Signaling-Induced Cancer Cell Reprogramming as a Driver of Tumor Relapse
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  178. www.nature.com www.nature.com
    A chemical toolbox for the study of bromodomains and epigenetic signaling
    1
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      anti-H3

      DOI: 10.1038/s41467-019-09672-2

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  179. academic.oup.com academic.oup.com
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      RRID:AB_302613

      DOI: 10.1093/nar/gky232

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  180. www.sciencedirect.com www.sciencedirect.com
    Widespread Accumulation of Ribosome-Associated Isolated 3′ UTRs in Neuronal Cell Populations of the Aging Brain
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      RRID:AB_302613

      DOI: 10.1016/j.celrep.2018.10.094

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      DOI: 10.1016/j.celrep.2018.11.035

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  182. elifesciences.org elifesciences.org
    The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage
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      DOI: 10.7554/eLife.23872

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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic Functional Annotation of Somatic Mutations in Cancer
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      DOI: 10.1016/j.ccell.2018.01.021

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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Species specific differences in use of ANP32 proteins by influenza A virus
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      AB_1791

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  186. www.sciencedirect.com www.sciencedirect.com
    The Nuclear Matrix Protein SAFB Cooperates with Major Satellite RNAs to Stabilize Heterochromatin Architecture Partially through Phase Separation
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      DOI: 10.1016/j.molcel.2019.10.001

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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    VAL genes regulate vegetative phase change via miR156-dependent and independent mechanisms
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    Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination
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  190. Jun 2021
  191. www.sciencedirect.com www.sciencedirect.com
    The Polycomb group protein MEDEA controls cell proliferation and embryonic patterning in Arabidopsis
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    The nuclear kinesin KIF18B promotes 53BP1-mediated DNA double-strand break repair
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    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
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    Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin
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  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A TORC1-histone axis regulates chromatin organisation and non-canonical induction of autophagy to ameliorate ageing
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  196. link.springer.com link.springer.com
    Programmed suppression of oxidative phosphorylation and mitochondrial function by gestational alcohol exposure correlate with widespread increases in H3K9me2 that do not suppress transcription
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      DOI: 10.1186/s13072-021-00403-w

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    Correct dosage of X chromosome transcription is controlled by a nuclear pore component
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    XRCC1 prevents toxic PARP1 trapping during DNA base excision repair
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    Cystatin B-deficiency triggers ectopic histone H3 tail cleavage during neurogenesis
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      DOI: 10.1016/j.nbd.2021.105418

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    sciencedirect.com/science/article/pii/S0969996121001674
  200. bmcbiol.biomedcentral.com bmcbiol.biomedcentral.com
    Boundaries potentiate polycomb response element-mediated silencing
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      DOI: 10.1186/s12915-021-01047-8

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    Uncovering the RNA-binding protein landscape in the pluripotency network of human embryonic stem cells
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      DOI: 10.1016/j.celrep.2021.109198

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    Choline kinase alpha 2 acts as a protein kinase to promote lipolysis of lipid droplets
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  203. May 2021
  204. www.nature.com www.nature.com
    Guiding functions of the C-terminal domain of topoisomerase IIα advance mitotic chromosome assembly
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      DOI: 10.1038/s41467-021-23205-w

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  205. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein
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      rabbit polyclonal anti-histone H3

      DOI: 10.1002/ijc.33562

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33562
  206. www.sciencedirect.com www.sciencedirect.com
    Human telomerase is directly regulated by non-telomeric TRF2-G-quadruplex interaction
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      RRID:AB_302613

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    sciencedirect.com/science/article/pii/S2211124721004964
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    CloneSeq: A highly sensitive analysis platform for the characterization of 3D-cultured single-cell-derived clones
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      DOI: 10.1016/j.devcel.2021.04.026

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    The PP2A-Integrator-CDK9 axis fine-tunes transcription and can be targeted therapeutically in cancer
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      DOI: 10.1016/j.cell.2021.04.022

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    DHODH inhibition modulates glucose metabolism and circulating GDF15, and improves metabolic balance
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    Missense mutations in small muscle protein X-linked ( SMPX ) cause distal myopathy with protein inclusions
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      DOI: 10.1007/s00401-021-02319-x

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    Methylation of histone H3 at lysine 37 by Set1 and Set2 prevents spurious DNA replication
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  212. journals.physiology.org journals.physiology.org
    Inhibition of miR-155 potentially protects Lipopolysaccharide-induced acute lung injury through the IRF2BP2-NFAT1 pathway
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      DOI: 10.1152/ajpcell.00116.2020

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    Spermiogenic histone transitions and chromatin decondensation in Decapoda
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      DOI: 10.1016/j.theriogenology.2020.07.003

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