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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Proteomic and functional comparison between human induced and embryonic stem cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC11563575/
  3. Dec 2024
  4. www.sciencedirect.com www.sciencedirect.com
    The ATAC complex represses the transcriptional program of the autophagy-lysosome pathway via its E3 ubiquitin ligase activity
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    sciencedirect.com/science/article/pii/S2211124724013846
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    EZH2 inhibition enhances T cell immunotherapies by inducing lymphoma immunogenicity and improving T cell function
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    sciencedirect.com/science/article/pii/S1535610824004410
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    An orphan gene BOOSTER enhances photosynthetic efficiency and plant productivity
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    sciencedirect.com/science/article/pii/S1534580724006671
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    Nucleo-cytosolic acetyl-CoA drives tumor immune evasion by regulating PD-L1 in melanoma
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    sciencedirect.com/science/article/pii/S2211124724013664
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    ACSS1-dependent acetate utilization rewires mitochondrial metabolism to support AML and melanoma tumor growth and metastasis
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    sciencedirect.com/science/article/pii/S2211124724013391
  9. Nov 2024
  10. pubs.acs.org pubs.acs.org
    Molecular Mechanism of Fusarium Fungus Inhibition by Phenazine-1-carboxamide
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    pubs.acs.org/doi/10.1021/acs.jafc.4c03936
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    STK19 facilitates the clearance of lesion-stalled RNAPII during transcription-coupled DNA repair
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    sciencedirect.com/science/article/pii/S0092867424012005
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    A p38 MAPK-ROS axis fuels proliferation stress and DNA damage during CRISPR-Cas9 gene editing in hematopoietic stem and progenitor cells
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    sciencedirect.com/science/article/pii/S2666379124005949
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Substrate specificity and protein stability drive the divergence of plant-specific DNA methyltransferases
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    1. scibot 10 Nov 2024
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      DOI: 10.1126/sciadv.adr2222

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  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Non-cell-autonomous regulation of germline proteostasis by insulin/IGF-1 signaling-induced dietary peptide uptake via PEPT-1
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  15. Oct 2024
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    Inactive Parp2 causes Tp53-dependent lethal anemia by blocking replication-associated nick ligation in erythroblasts
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    sciencedirect.com/science/article/pii/S1097276524007767
  17. Sep 2024
  18. www.sciencedirect.com www.sciencedirect.com
    m6A-modified cenRNA stabilizes CENPA to ensure centromere integrity in cancer cells
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    sciencedirect.com/science/article/pii/S0092867424009693
  19. Aug 2024
  20. www.biorxiv.org www.biorxiv.org
    Functional mapping of epigenetic regulators uncovers coordinated tumor suppression by the HBO1 and MLL1 complexes
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    Legionella pneumophila modulates macrophage functions through epigenetic reprogramming via the C-type lectin receptor Mincle
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    sciencedirect.com/science/article/pii/S2589004224019254
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Artificially inserted strong promoter containing multiple G-quadruplexes induces long-range chromatin modification
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      DOI: 10.7554/eLife.96216

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    ncbi.nlm.nih.gov/pmc/articles/PMC11333042/
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    A CLIC1 network coordinates matrix stiffness and the Warburg effect to promote tumor growth in pancreatic cancer
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    Exosomes-mediated retinoic acid disruption: A link between gut microbiota depletion and impaired spermatogenesis
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    sciencedirect.com/science/article/pii/S0300483X24001884
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    A High-Throughput Screening Identifies MCM Chromatin loading Inhibitors Targeting Cells with increased Replication Origins
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    sciencedirect.com/science/article/pii/S2589004224017929
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    FolIws1-driven nuclear translocation of deacetylated FolTFIIS ensures conidiation of Fusarium oxysporum
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    sciencedirect.com/science/article/pii/S2211124724009173
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    Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions
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    sciencedirect.com/science/article/pii/S1534580724004453
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    Mapping the dynamics of epigenetic adaptation in S. pombe during heterochromatin misregulation
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    sciencedirect.com/science/article/pii/S1534580724004441
  30. www.biorxiv.org www.biorxiv.org
    Diptera-specific Daedalus controls Zucchini endonucleolysis in piRNA biogenesis independent of exonucleases
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  31. www.embopress.org www.embopress.org
    1,10-phenanthroline inhibits sumoylation and reveals that yeast SUMO modifications are highly transient
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  32. academic.oup.com academic.oup.com
    Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz(Wwtr1) Activation in Male LDLR-/- Mice
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      DOI: 10.1210/endocr/bqad192

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  33. journals.physiology.org journals.physiology.org
    Progesterone and estrogen regulate NALCN expression in human myometrial smooth muscle cells | American Journal of Physiology-Endocrinology and Metabolism
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      DOI: 10.1152/ajpendo.00320.2019

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    Phosphorylation of H3-Thr3 by Haspin Is Required for Primary Cilia Regulation
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      DOI: 10.3390/ijms22147753

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  35. pubs.acs.org pubs.acs.org
    Molecular Mechanism of Fusarium Fungus Inhibition by Phenazine-1-carboxamide
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      DOI: 10.1021/acs.jafc.4c03936

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  36. Jul 2024
  37. www.sciencedirect.com www.sciencedirect.com
    Acetyl-CoA metabolism maintains histone acetylation for syncytialization of human placental trophoblast stem cells
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    sciencedirect.com/science/article/pii/S1934590924002534
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    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
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    sciencedirect.com/science/article/pii/S2211124724008258
  39. www.cell.com www.cell.com
    DOT1L/H3K79me2 represses HIV-1 reactivation via recruiting DCAF1
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    cell.com/cell-reports/fulltext/S2211-1247(24)00696-X
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    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    sciencedirect.com/science/article/pii/S2211124724007939
  41. www.cell.com www.cell.com
    Genome-wide quantification of RNA flow across subcellular compartments reveals determinants of the mammalian transcript life cycle
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    cell.com/molecular-cell/fulltext/S1097-2765(24)00511-2
  42. www.cell.com www.cell.com
    YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment
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    cell.com/cell-reports/abstract/S2211-1247(24)00785-X
  43. Jun 2024
  44. onlinelibrary.wiley.com onlinelibrary.wiley.com
    FUS Selectively Facilitates circRNAs Packing into Small Extracellular Vesicles within Hypoxia Neuron
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      DOI: 10.1002/advs.202404822

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    onlinelibrary.wiley.com/doi/10.1002/advs.202404822
  45. www.sciencedirect.com www.sciencedirect.com
    An enhancer RNA recruits KMT2A to regulate transcription of Myb
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    sciencedirect.com/science/article/pii/S221112472400706X
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    PKD1 mutant clones within cirrhotic livers inhibit steatohepatitis without promoting cancer
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    sciencedirect.com/science/article/pii/S1550413124001918
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    DOT1L maintains NK cell phenotype and function for optimal tumor control
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      DOI: 10.1016/j.celrep.2024.114333

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    sciencedirect.com/science/article/pii/S2211124724006612
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The roles of nuclear orphan receptor NR2F6 in anti-viral innate immunity
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      DOI: 10.1371/journal.ppat.1012271

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    Lineage specification in glioblastoma is regulated by METTL7B
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    Altered nucleocytoplasmic export of adenosine-rich circRNAs by PABPC1 contributes to neuronal function
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    Endonucleolytic RNA cleavage drives changes in gene expression during the innate immune response
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    Characterization of a novel HDAC2 pathogenetic variant: a missing puzzle piece for chromatinopathies
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    Mitotic Activity and DNA Maintenance of Adult Neural Stem Cells is Regulated by Beclin1
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    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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    Noradrenaline enhances Na-K ATPase subunit expression by HuR-induced mRNA stabilization and their transportation to the cell surface through PLC and PKC mediated pathway: Implications with REMS-loss associated disorders
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  57. Apr 2024
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    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    H2AK119ub1 differentially fine-tunes gene expression by modulating canonical PRC1- and H1-dependent chromatin compaction
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    An RNA-dependent and phase-separated active subnuclear compartment safeguards repressive chromatin domains
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    EP300/CREBBP acetyltransferase inhibition limits steroid receptor and FOXA1 signaling in prostate cancer cells
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    Tumor cell-intrinsic epigenetic dysregulation shapes cancer-associated fibroblasts heterogeneity to metabolically support pancreatic cancer
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    Wnt16 Promotes Vascular Smooth Muscle Contractile Phenotype and Function via Taz(Wwtr1) Activation in Male LDLR-/- Mice
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  66. Mar 2024
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    ApoE maintains neuronal integrity via miRNA and H3K27me3-mediated repression.
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    Alternative splicing decouples local from global PRC2 activity
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  71. Feb 2024
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PCID2 dysregulates transcription and viral RNA processing to promote HIV-1 latency
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    Poly(ADP-ribosyl)ation of TIMELESS limits DNA replication stress and promotes stalled fork protection
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    Sustained antidepressant effects of ketamine metabolite involve GABAergic inhibition-mediated molecular dynamics in aPVT glutamatergic neurons
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    Concerted SUMO-targeted ubiquitin ligase activities of TOPORS and RNF4 are essential for stress management and cell proliferation
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    Histone methylation readers MRG1/2 interact with PIF4 to promote thermomorphogenesis in Arabidopsis
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    n-3 polyunsaturated fatty acids delay intervertebral disc degeneration by inhibiting nuclear receptor coactivator 4-mediated iron overload
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    H2A.Z histone variants facilitate HDACi-dependent removal of H3.3K27M mutant protein in pediatric high-grade glioma cells
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    PCGF6 controls murine Tuft cell differentiation via H3K9me2 modification independently of Polycomb repression
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    Discrete prefrontal neuronal circuits determine repeated stress-induced behavioral phenotypes in male mice
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    Chronic hypoxia stabilizes 3βHSD1 via autophagy suppression
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    TOR inactivation triggers heterochromatin formation in rDNA during glucose starvation
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    53BP1 interacts with the RNA primer from Okazaki fragments to support their processing during unperturbed DNA replication
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    Manipulating the 3D organization of the largest synthetic yeast chromosome
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    Debugging and consolidating multiple synthetic chromosomes reveals combinatorial genetic interactions
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    Age-related decline in spermatogenic activity accompanied with endothelial cell senescence in male mice
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    An atypical GABARAP binding module drives the pro-autophagic potential of the AML-associated NPM1c variant
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    Progesterone activates histone lactylation-Hif1α-glycolysis feedback loop to promote decidualization
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    RNA polymerase II dynamics and mRNA stability feedback scale mRNA amounts with cell size
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    Consequences of a telomerase-related fitness defect and chromosome substitution technology in yeast synIX strains
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    Smith–Magenis syndrome protein RAI1 regulates body weight homeostasis through hypothalamic BDNF-producing neurons and neurotrophin downstream signalling
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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  104. 52.53.155.43 52.53.155.43
    RBFOX2 regulated EYA3 isoforms partner with SIX4 or ZBTB1 to control transcription during myogenesis
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    The proteomic landscape of synaptic diversity across brain regions and cell types
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    The ubiquitin conjugase Rad6 mediates ribosome pausing during oxidative stress
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    Global identification of SWI/SNF targets reveals compensation by EP400
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    m6A demethylase FTO stabilizes LINK-A to exert oncogenic roles via MCM3-mediated cell-cycle progression and HIF-1α activation
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  109. Oct 2023
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    Short C-terminal Musashi-1 proteins regulate pluripotency states in embryonic stem cells
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    MircroRNA-92b as a Negative Regulator of the TGF-β Signaling by Targeting the Type I Receptor
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    A Haspin-ARHGAP11A axis regulates epithelial morphogenesis through Rho-ROCK dependent modulation of LIMK1-Cofilin
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    Splicing quality control mediated by DHX15 and its G-patch activator SUGP1
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    Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming
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    ATR protects ongoing and newly assembled DNA replication forks through distinct mechanisms
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    15-keto-PGE2 Alleviates Nonalcoholic Steatohepatitis through its Covalent Modification of NF-κB Factors
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    ATAC and SAGA co-activator complexes utilize co-translational assembly, but their cellular localization properties and functions are distinct
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  118. www.embopress.org www.embopress.org
    Hypoxia activates SREBP2 through Golgi disassembly in bone marrow-derived monocytes for enhanced tumor growth
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  119. Sep 2023
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    Antagonism among DUX family members evolved from an ancestral toxic single homeodomain protein
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone bivalency regulates the timing of cerebellar granule cell development
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    A distinct circular DNA profile intersects with proteome changes in the genotoxic stress-related hSOD1G93A model of ALS
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    Protocol to study the role of a human nuclear m6A RNA reader on chromatin-associated RNA targets
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    The SMC5/6 complex compacts and silences unintegrated HIV-1 DNA and is antagonized by Vpr
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    Human astrocytes and microglia show augmented ingestion of synapses in Alzheimer’s disease via MFG-E8
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  126. Aug 2023
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    Chromatin remodeling of histone H3 variants by DDM1 underlies epigenetic inheritance of DNA methylation
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    Mechanistic insights into nucleosomal H2B monoubiquitylation mediated by yeast Bre1-Rad6 and its human homolog RNF20/RNF40-hRAD6A
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    Targeting TCF19 sensitizes MSI endometrial cancer to anti-PD-1 therapy by alleviating CD8+ T cell exhaustion via TRIM14-IFN-β axis
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    High-throughput functional characterization of combinations of transcriptional activators and repressors
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    Histone variants shape chromatin states in Arabidopsis
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterogeneous non-canonical nucleosomes predominate in yeast cells in situ
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  134. Jul 2023
  135. www.sciencedirect.com www.sciencedirect.com
    Histone H1 protects telomeric repeats from H3K27me3 invasion in Arabidopsis
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    Thymine DNA glycosylase regulates cell-cycle-driven p53 transcriptional control in pluripotent cells
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    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    Widespread dysregulation of mRNA splicing implicates RNA processing in the development and progression of Huntington's disease
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    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    Upregulation of EphA4 deteriorate brain damage by shifting microglia M1-polarization via NF-κB signaling after focal cerebral ischemia in rats
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    SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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    Alcohol-sourced acetate impairs T cell function by promoting cortactin acetylation
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    OsTOC1 plays dual roles in the regulation of plant circadian clock by functioning as a direct transcription activator or repressor
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    TONSOKU is required for the maintenance of repressive chromatin modifications in Arabidopsis
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    Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies
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  150. Jun 2023
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    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
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    The OsbHLH002/OsICE1-OSH1 module orchestrates secondary cell wall formation in rice
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    SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma
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    Compromised nonsense-mediated RNA decay results in truncated RNA-binding protein production upon DUX4 expression
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    Haploinsufficiency of NFKBIA reshapes the epigenome antipodal to the IDH mutation and imparts disease fate in diffuse gliomas
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    SAM-Competitive EZH2-Inhibitors Induce Platinum Resistance by EZH2-Independent Induction of ABC-Transporters
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    Resistance to mesenchymal reprogramming sustains clonal propagation in metastatic breast cancer
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  163. May 2023
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    Global identification of direct SWI/SNF targets reveals compensation by EP400
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  165. www.biorxiv.org www.biorxiv.org
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    Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity
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    Airway dysbiosis accelerates lung function decline in chronic obstructive pulmonary disease
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  172. www.science.org www.science.org
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  173. Apr 2023
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    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    NSD1 deposits histone H3 lysine 36 dimethylation to pattern non-CG DNA methylation in neurons
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    Reduced histone gene copy number disrupts Drosophila Polycomb function
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    Compartmentalization of the SUMO/RNF4 pathway by SLX4 drives DNA repair
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    Release of Histone H3K4-reading transcription factors from chromosomes in mitosis is independent of adjacent H3 phosphorylation
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    PRC2.1- and PRC2.2-specific accessory proteins drive recruitment of different forms of canonical PRC1
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    Sodium ion influx regulates liquidity of biomolecular condensates in hyperosmotic stress response
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    TRIM28 represses renal cell carcinoma cell proliferation by inhibiting TFE3/KDM6A-regulated autophagy
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    Single substitution in H3.3G34 alters DNMT3A recruitment to cause progressive neurodegeneration
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    A central chaperone-like role for 14-3-3 proteins in human cells
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    Estradiol regulates leptin sensitivity to control feeding via hypothalamic Cited1
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    Dodecaploid Xenopus longipes provides insight into the emergence of size scaling relationships during development
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    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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    Exposure to high-sugar diet induces transgenerational changes in sweet sensitivity and feeding behavior via H3K27me3 reprogramming
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    JMJ28 guides sequence-specific targeting of ATX1/2-containing COMPASS-like complex in Arabidopsis
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    Histone bivalency regulates the timing of cerebellar granule cell development
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    The termination of UHRF1-dependent PAF15 ubiquitin signaling is regulated by USP7 and ATAD5
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    Multiple ubiquitin E3 ligase genes antagonistically regulate chloroplast-associated protein degradation
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    Isolating Mitochondria, Mitoplasts, and mtDNA from Cultured Mammalian Cells
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    A Pro-Regenerative Environment Triggers Premalignant to Malignant Transformation of Senescent Hepatocytes
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    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
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    Epitranscriptomic regulation of cortical neurogenesis via Mettl8-dependent mitochondrial tRNA m3C modification
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    Recycling of modified H2A-H2B provides short-term memory of chromatin states
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    RIF1 suppresses the formation of single-stranded ultrafine anaphase bridges via protein phosphatase 1
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    GEN1 promotes common fragile site expression
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    Decoding m6A RNA methylome identifies PRMT6-regulated lipid transport promoting AML stem cell maintenance
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    BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency
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    Single-copy locus proteomics of early- and late-firing DNA replication origins identifies a role of Ask1/DASH complex in replication timing control
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    RNA mis-splicing drives viral mimicry response after DNMTi therapy in SETD2-mutant kidney cancer
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    MDC1 maintains active elongation complexes of RNA polymerase II
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    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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    SETD2 haploinsufficiency enhances germinal center-associated AICDA somatic hypermutation to drive B cell lymphomagenesis
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    Developmental phenomics suggests that H3K4 monomethylation confers multi-level phenotypic robustness
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    Hypoxia induces transgenerational epigenetic inheritance of small RNAs
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    Chromatin-associated YTHDC1 coordinates heat-induced reprogramming of gene expression
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    Cystatin B deficiency results in sustained histone H3 tail cleavage in postnatal mouse brain mediated by increased chromatin-associated cathepsin L activity
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    NEDDylated Cullin 3 mediates the adaptive response to topoisomerase 1 inhibitors
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    Excessive proteostasis contributes to pathology in fragile X syndrome
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    PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing
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