267 Matching Annotations
  1. Sep 2020
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    Modeling Human Cytomegalovirus-Induced Microcephaly in Human iPSC-Derived Brain Organoids
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      DOI: 10.1016/j.xcrm.2020.100002

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    sciencedirect.com/science/article/pii/S2666379120300021
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    Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2
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      DOI: 10.1016/j.celrep.2020.107609

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      DOI: 10.1126/scisignal.aax6490

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    stke.sciencemag.org/content/sigtrans/suppl/2020/01/24/13.616.eaax6490.DC1/aax6490_SM.pdf
  5. Jan 2020
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    A Systems Pharmacology Approach Uncovers Wogonoside as an Angiogenesis Inhibitor of Triple-Negative Breast Cancer by Targeting Hedgehog Signaling
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    sciencedirect.com/science/article/pii/S2451945619301734
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    Pervasive Chromatin-RNA Binding Protein Interactions Enable RNA-Based Regulation of Transcription
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    cell.com/cell/fulltext/S0092-8674(19)30629-4
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    A TAZ-AXL-ABL2 Feed-Forward Signaling Axis Promotes Lung Adenocarcinoma Brain Metastasis
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    sciencedirect.com/science/article/pii/S2211124719314895
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    NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor
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      DOI: 10.1016/j.celrep.2019.09.087

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    sciencedirect.com/science/article/pii/S2211124719312914
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    Targeting Spt5-Pol II by Small-Molecule Inhibitors Uncouples Distinct Activities and Reveals Additional Regulatory Roles
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    sciencedirect.com/science/article/pii/S109727651930663X
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    The N-Degron Pathway Mediates ER-phagy
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    Interleukin-17 Regulates Neuron-Glial Communications, Synaptic Transmission, and Neuropathic Pain after Chemotherapy
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  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequential phosphorylation of NDEL1 by the DYRK2-GSK3β complex is critical for neuronal morphogenesis
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      DOI: 10.7554/eLife.50850

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    ncbi.nlm.nih.gov/pmc/articles/PMC6927744/
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    TOM40 Targets Atg2 to Mitochondria-Associated ER Membranes for Phagophore Expansion
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      DOI: 10.1016/j.celrep.2019.07.036

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    sciencedirect.com/science/article/pii/S2211124719309337
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    Template Activating Factor-I α Regulates Retroviral Silencing during Reprogramming
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.celrep.2019.10.010

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    Divergent Polypharmacology-Driven Cellular Activity of Structurally Similar Multi-Kinase Inhibitors through Cumulative Effects on Individual Targets
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      DOI: 10.1016/j.chembiol.2019.06.003

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    Recurrent SMARCB1 Mutations Reveal a Nucleosome Acidic Patch Interaction Site That Potentiates mSWI/SNF Complex Chromatin Remodeling
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    1. scibot 13 Jan 2020
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      DOI: 10.1016/j.cell.2019.10.044

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    sciencedirect.com/science/article/pii/S0092867419312218
  18. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A bivalent antihypertensive vaccine targeting L‐type calcium channel and angiotensin II type 1 receptor
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    1. scibot 13 Jan 2020
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      DOI: 10.1111/bph.14875

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14875
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    SAMHD1 Modulates Early Steps during Human Cytomegalovirus Infection by Limiting NF-κB Activation
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      DOI: 10.1016/j.celrep.2019.06.027

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    sciencedirect.com/science/article/pii/S2211124719307934
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    A Homeostatic Arid1a-Dependent Permissive Chromatin State Licenses Hepatocyte Responsiveness to Liver-Injury-Associated YAP Signaling
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      DOI: 10.1016/j.stem.2019.06.008

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    sciencedirect.com/science/article/pii/S1934590919302723
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    YAP/TAZ Activation Drives Uveal Melanoma Initiation and Progression
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      DOI: 10.1016/j.celrep.2019.03.021

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    sciencedirect.com/science/article/pii/S2211124719303286
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    α-Ketoglutarate-Activated NF-κB Signaling Promotes Compensatory Glucose Uptake and Brain Tumor Development
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      DOI: 10.1016/j.molcel.2019.07.007

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    sciencedirect.com/science/article/pii/S1097276519305374
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    SUMO-Chain-Regulated Proteasomal Degradation Timing Exemplified in DNA Replication Initiation
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      DOI: 10.1016/j.molcel.2019.08.003

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    sciencedirect.com/science/article/pii/S1097276519306197
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    53BP1 Supports Immunoglobulin Class Switch Recombination Independently of Its DNA Double-Strand Break End Protection Function
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      DOI: 10.1016/j.celrep.2019.06.035

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    sciencedirect.com/science/article/pii/S2211124719308010
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      DOI: 10.1016/j.stem.2019.01.002

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    sciencedirect.com/science/article/pii/S1934590919300025
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      DOI: 10.1016/j.celrep.2019.01.075

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    sciencedirect.com/science/article/pii/S2211124719301044
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    KRAS Suppression-Induced Degradation of MYC Is Antagonized by a MEK5-ERK5 Compensatory Mechanism
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      DOI: 10.1016/j.ccell.2018.10.001

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    Direct Induction of the Three Pre-implantation Blastocyst Cell Types from Fibroblasts
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      DOI: 10.1016/j.stem.2019.03.018

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    Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer
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      DOI: 10.1016/j.celrep.2018.11.093

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      DOI: 10.1016/j.molcel.2019.03.006

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    Targeting an RNA-Binding Protein Network in Acute Myeloid Leukemia
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  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FOXM1 Deubiquitination by USP21 Regulates Cell Cycle Progression and Paclitaxel Sensitivity in Basal-like Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC6425951/
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      DOI: 10.1016/j.neuron.2019.02.011

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      DOI: 10.1016/j.devcel.2019.04.018

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    Parvifoline AA Promotes Susceptibility of Hepatocarcinoma to Natural Killer Cell-Mediated Cytolysis by Targeting Peroxiredoxin
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  39. Nov 2018
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    sciencedirect.com/science/article/pii/S2211124718315286
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    MYC Interacts with the G9a Histone Methyltransferase to Drive Transcriptional Repression and Tumorigenesis
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    XBP1-KLF9 Axis Acts as a Molecular Rheostat to Control the Transition from Adaptive to Cytotoxic Unfolded Protein Response
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    sciencedirect.com/science/article/pii/S2211124718314438
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    Bi-allelic Loss of CDKN2A Initiates Melanoma Invasion via BRN2 Activation
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    LSD1 Ablation Stimulates Anti-tumor Immunity and Enables Checkpoint Blockade
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    UBE2M Is a Stress-Inducible Dual E2 for Neddylation and Ubiquitylation that Promotes Targeted Degradation of UBE2F
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    SETD7 Drives Cardiac Lineage Commitment through Stage-Specific Transcriptional Activation
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    APC Inhibits Ligand-Independent Wnt Signaling by the Clathrin Endocytic Pathway
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    Angiogenin/Ribonuclease 5 Is an EGFR Ligand and a Serum Biomarker for Erlotinib Sensitivity in Pancreatic Cancer
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    Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation
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    EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation
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    Mutant p53 Gains Its Function via c-Myc Activation upon CDK4 Phosphorylation at Serine 249 and Consequent PIN1 Binding
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    Fc gamma receptors are expressed in the developing rat brain and activate downstream signaling molecules upon cross-linking with immune complex
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  56. Nov 2017
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    Cdk5 Regulation of the GRAB-Mediated Rab8-Rab11 Cascade in Axon Outgrowth
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  58. onlinelibrary.wiley.com onlinelibrary.wiley.com
    PRMT1 regulates astrocytic differentiation of embryonic neural stem/precursor cells
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    CHD4 Has Oncogenic Functions in Initiating and Maintaining Epigenetic Suppression of Multiple Tumor Suppressor Genes
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    Development of Peptidomimetic Inhibitors of the ERG Gene Fusion Product in Prostate Cancer
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  64. elifesciences.org elifesciences.org
    Control of immune ligands by members of a cytomegalovirus gene expansion suppresses natural killer cell activation
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    Phosphoglycerate Kinase 1 Phosphorylates Beclin1 to Induce Autophagy
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    A Rapid Induction Mechanism for Lin28a in Trophic Responses
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    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
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    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
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