267 Matching Annotations
  1. Dec 2024
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
    1
    1. scibot 12 Dec 2024
      RRID:AB_737182

      DOI: 10.1158/0008-5472.CAN-24-1102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  3. Nov 2024
  4. www.sciencedirect.com www.sciencedirect.com
    Autophagy-dependent splicing control directs translation toward inflammation during senescence
    1
    1. scibot 16 Nov 2024
      RRID:AB_737182

      DOI: 10.1016/j.devcel.2024.10.008

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    sciencedirect.com/science/article/pii/S1534580724006270
  5. Sep 2024
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZEB1 Inhibits LHβ Subunit Transcription When Overexpressed, but Is Dispensable for LH Synthesis in Mice
    1
    1. scibot 27 Sep 2024
      RRID:AB_737182

      DOI: 10.1210/endocr/bqae116

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    ncbi.nlm.nih.gov/pmc/articles/PMC11422717/
  7. www.sciencedirect.com www.sciencedirect.com
    A tripartite circRNA/mRNA/miRNA interaction regulates glutamatergic signaling in the mouse brain
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114766

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    sciencedirect.com/science/article/pii/S2211124724011173
  8. www.sciencedirect.com www.sciencedirect.com
    C2H2-zinc-finger transcription factors bind RNA and function in diverse post-transcriptional regulatory processes
    1
    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.molcel.2024.08.037

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    sciencedirect.com/science/article/pii/S1097276524007330
  9. www.sciencedirect.com www.sciencedirect.com
    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.devcel.2024.08.009

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    sciencedirect.com/science/article/pii/S1534580724004921
  10. Aug 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFE3 fusions direct an oncogenic transcriptional program that drives OXPHOS and unveils vulnerabilities in translocation renal cell carcinoma
    1
    1. scibot 26 Aug 2024
      RRID:AB_737182

      DOI: 10.1101/2024.08.09.607311

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    ncbi.nlm.nih.gov/pmc/articles/PMC11326252/
  12. www.sciencedirect.com www.sciencedirect.com
    Increased viral tolerance mediates by antiviral RNA interference in bat cells
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114581

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    sciencedirect.com/science/article/pii/S2211124724009100
  13. www.cell.com www.cell.com
    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
    1
    1. scibot 02 Aug 2024
      AB_737182

      DOI: 10.1016/s0002-9270(97)00059-2

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    cell.com/action/showExperimentalProcedures
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
    1
    1. scibot 02 Aug 2024
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      DOI: 10.1002/dneu.22280

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    onlinelibrary.wiley.com/doi/10.1002/dneu.22280/full
  15. Jul 2024
  16. www.sciencedirect.com www.sciencedirect.com
    Isogenic patient-derived organoids reveal early neurodevelopmental defects in spinal muscular atrophy initiation
    1
    1. scibot 27 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.xcrm.2024.101659

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    sciencedirect.com/science/article/pii/S2666379124003732
  17. www.sciencedirect.com www.sciencedirect.com
    Dysregulation of FLVCR1a-dependent mitochondrial calcium handling in neural progenitors causes congenital hydrocephalus
    1
    1. scibot 17 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.xcrm.2024.101647

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    sciencedirect.com/science/article/pii/S2666379124003616
  18. www.cell.com www.cell.com
    YY1-mediated enhancer-promoter communication in the immunoglobulin μ locus is regulated by MSL/MOF recruitment
    1
    1. scibot 16 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114456

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    cell.com/cell-reports/abstract/S2211-1247(24)00785-X
  19. www.cell.com www.cell.com
    A non-canonical role for a small nucleolar RNA in ribosome biogenesis and senescence
    1
    1. scibot 11 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.cell.2024.06.019

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    cell.com/cell/fulltext/S0092-8674(24)00693-7
  20. www.sciencedirect.com www.sciencedirect.com
    Dystrophin 71 deficiency causes impaired aquaporin-4 polarization contributing to glymphatic dysfunction and brain edema in cerebral ischemia
    2
    1. scibot 04 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.nbd.2024.106586

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    2. scibot 04 Jul 2024
      RRID:AB_737182

      DOI: 10.1016/j.nbd.2024.106586

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    sciencedirect.com/science/article/pii/S0969996124001864
  21. Jun 2024
  22. www.sciencedirect.com www.sciencedirect.com
    An enhancer RNA recruits KMT2A to regulate transcription of Myb
    1
    1. scibot 21 Jun 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114378

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    sciencedirect.com/science/article/pii/S221112472400706X
  23. www.sciencedirect.com www.sciencedirect.com
    Antibody-activation of connexin hemichannels in bone osteocytes with ATP release suppresses breast cancer and osteosarcoma malignancy
    1
    1. scibot 21 Jun 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114377

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    sciencedirect.com/science/article/pii/S2211124724007058
  24. elifesciences.org elifesciences.org
    RAPSYN-mediated neddylation of BCR-ABL alternatively determines the fate of Philadelphia chromosome-positive leukemia
    1
    1. scibot 14 Jun 2024
      RRID:AB_737182

      DOI: 10.7554/eLife.88375

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    elifesciences.org/articles/88375
  25. www.sciencedirect.com www.sciencedirect.com
    A CD36-dependent non-canonical lipid metabolism program promotes immune escape and resistance to hypomethylating agent therapy in AML
    1
    1. scibot 06 Jun 2024
      AB_737182

      DOI: 10.1016/j.xcrm.2024.101592

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    sciencedirect.com/science/article/pii/S2666379124002842
  26. May 2024
  27. aacrjournals.org aacrjournals.org
    LINC00869 promotes hepatocellular carcinoma metastasis via protrusion formation
    1
    1. scibot 23 May 2024
      AB_737182

      DOI: 10.1158/1541-7786.MCR-23-0414

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    aacrjournals.org/mcr/article/22/3/282/734709/LINC00869-Promotes-Hepatocellular-Carcinoma
  28. www.sciencedirect.com www.sciencedirect.com
    Cardiolipin oxidized by ROS from complex II acts as a target of gasdermin D to drive mitochondrial pore and heart dysfunction in endotoxemia
    1
    1. scibot 16 May 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114237

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    sciencedirect.com/science/article/pii/S2211124724005655
  29. Apr 2024
  30. www.sciencedirect.com www.sciencedirect.com
    O-GlcNAcylation of RBM14 contributes to elevated cellular O-GlcNAc through regulation of OGA protein stability
    1
    1. scibot 30 Apr 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114163

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    sciencedirect.com/science/article/pii/S2211124724004911
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HDAC10 inhibition represses melanoma cell growth and BRAF inhibitor resistance via upregulating SPARC expression
    1
    1. scibot 24 Apr 2024
      RRID:AB_737182

      DOI: 10.1093/narcan/zcae018

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    ncbi.nlm.nih.gov/pmc/articles/PMC11034028/
  32. aacrjournals.org aacrjournals.org
    Adipose triglyceride lipase is a therapeutic target in advanced prostate cancer that promotes metabolic plasticity
    1
    1. scibot 19 Apr 2024
      RRID:AB_737182

      DOI: 10.1158/0008-5472.CAN-23-0555

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    aacrjournals.org/cancerres/article/84/5/703/734936/Adipose-Triglyceride-Lipase-Is-a-Therapeutic
  33. 52.53.155.43 52.53.155.43
    gaae015-html.html
    1
    1. scibot 19 Apr 2024
      RRID:AB_737182

      DOI: 10.1093/molehr/gaae015

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    52.53.155.43/2937ae15ffb949fde49a3f9100cc82616d52fb7b/gaae015-html.html
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Female-specific dysfunction of sensory neocortical circuits in a mouse model of autism mediated by mGluR5 and estrogen receptor α
    3
    1. scibot 09 Apr 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114056

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    2. scibot 09 Apr 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114056

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    3. scibot 09 Apr 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.114056

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    ncbi.nlm.nih.gov/pmc/articles/PMC11112681/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3 couples activated tyrosine kinase signaling to the oncogenic core transcriptional regulatory circuitry of anaplastic large cell lymphoma
    1
    1. scibot 03 Apr 2024
      RRID:AB_737182

      DOI: 10.1016/j.xcrm.2024.101472

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    ncbi.nlm.nih.gov/pmc/articles/PMC10983107/
  36. Mar 2024
  37. www.nature.com www.nature.com
    FEAR antiviral response pathway is independent of interferons and countered by poxvirus proteins
    1
    1. scibot 28 Mar 2024
      RRID:AB_737182

      DOI: 10.1038/s41564-024-01646-5

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    nature.com/articles/s41564-024-01646-5
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TLR2 regulates hair follicle cycle and regeneration via BMP signaling
    1
    1. scibot 16 Mar 2024
      RRID:AB_737182

      DOI: 10.7554/eLife.89335

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    ncbi.nlm.nih.gov/pmc/articles/PMC10939499/
  39. www.sciencedirect.com www.sciencedirect.com
    Poxvirus A51R proteins regulate microtubule stability and antagonize a cell-intrinsic antiviral response
    1
    1. scibot 08 Mar 2024
      RRID:AB_737182

      DOI: 10.1016/j.celrep.2024.113882

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    sciencedirect.com/science/article/pii/S2211124724002109
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RTF2 controls replication repriming and ribonucleotide excision at the replisome
    1
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      DOI: 10.1038/s41467-024-45947-z

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    ncbi.nlm.nih.gov/pmc/articles/PMC10908796/
  41. Feb 2024
  42. 52.53.155.43 52.53.155.43
    can-23-0555-html.html
    3
    1. scibot 23 Feb 2024
      RRID:AB_737182

      DOI: 10.1158/0008-5472.can-23-0555

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      RRID:AB_737182

      DOI: 10.1158/0008-5472.can-23-0555

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      DOI: 10.1158/0008-5472.can-23-0555

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    52.53.155.43/e8db3efafb8a8253e8641e16f59e9a4a6a668dad/can-23-0555-html.html
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human iPSC-derived closed-loop cardiac tissue for drug assessment
    1
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      RRID:AB_737182

      DOI: 10.1016/j.isci.2024.108992

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    ncbi.nlm.nih.gov/pmc/articles/PMC10850789/
  44. www.biorxiv.org www.biorxiv.org
    HDAC10 blockade upregulates SPARC expression thereby repressing melanoma cell growth and BRAF inhibitor resistance
    3
    1. scibot 09 Feb 2024
      RRID:AB_737182

      DOI: 10.1101/2023.12.05.570182

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      RRID:AB_737182

      DOI: 10.1101/2023.12.05.570182

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    3. scibot 09 Feb 2024
      RRID:AB_737182

      DOI: 10.1101/2023.12.05.570182

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    biorxiv.org/content/10.1101/2023.12.05.570182v1
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide p63-target gene analyses reveal TAp63/NRF2-dependent oxidative stress responses
    1
    1. scibot 03 Feb 2024
      RRID:AB_737182

      DOI: 10.1158/2767-9764.CRC-23-0358

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    ncbi.nlm.nih.gov/pmc/articles/PMC10832605/
  46. Jan 2024
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR/Cas9 screening identifies a targetable MEST-PURA interaction in cancer metastasis
    1
    1. scibot 26 Jan 2024
      AB_737182

      DOI: 10.1016/j.ebiom.2023.104587

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    ncbi.nlm.nih.gov/pmc/articles/PMC10192437/
  48. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
    1
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  49. Dec 2023
  50. www.sciencedirect.com www.sciencedirect.com
    YTHDF3 modulates the Cbln1 level by recruiting BTG2 and is implicated in the impaired cognition of prenatal hypoxia offspring
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    Decoupling NAD+ metabolic dependency in chondrosarcoma by targeting the SIRT1-HIF-2α axis
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    ASCL1 characterizes adrenergic neuroblastoma via its pioneer function and cooperation with core regulatory circuit factors
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    IDR-targeting compounds suppress HPV genome replication via disruption of phospho-BRD4 association with DNA damage response factors
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    Ovarian ERβ cistrome and transcriptome reveal chromatin interaction with LRH-1
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  55. Nov 2023
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    A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment
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    Differential network analysis of ROS1 inhibitors reveals lorlatinib polypharmacology through co-targeting PYK2
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  58. Oct 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    WIP1 is a novel specific target for growth hormone action
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    Lipid accumulation-mediated histone hypoacetylation drives persistent NK cell dysfunction in anti-tumor immunity
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  61. Sep 2023
  62. www.nature.com www.nature.com
    Low glucose metabolite 3-phosphoglycerate switches PHGDH from serine synthesis to p53 activation to control cell fate
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  63. Aug 2023
  64. 52.53.155.43 52.53.155.43
    Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function
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  65. Jul 2023
  66. www.sciencedirect.com www.sciencedirect.com
    Sox10 escalates vascular inflammation by mediating vascular smooth muscle cell transdifferentiation and pyroptosis in neointimal hyperplasia
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanical manipulation of cancer cell tumorigenicity via heat shock protein signaling
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    CRIC-seq protocol for in situ profiling of proximal RNA-RNA contacts associated with RNA-binding proteins
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  70. Jun 2023
  71. www.sciencedirect.com www.sciencedirect.com
    Polycomb repressive complex 2 binds and stabilizes NANOG to suppress differentiation-related genes to promote self-renewal
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    Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin
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  73. academic.oup.com academic.oup.com
    The Transmembrane Protein TM4SF3 Interacts with AR and AR-V7 and is Recruited to AR Target Genes
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      DOI: 10.1210/endocr/bqad048

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  74. May 2023
  75. link.springer.com link.springer.com
    Circular RNAs arising from synaptic host genes during human neuronal differentiation are modulated by SFPQ RNA-binding protein
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  76. 52.53.155.43 52.53.155.43
    BMP4 triggers regulatory circuits specifying the cardiac mesoderm lineage
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    RNA polymerase drives ribonucleotide excision DNA repair in E. coli
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  78. aacrjournals.org aacrjournals.org
    Transcriptional repression by FoxM1 suppresses tumor differentiation and promotes metastasis of breast cancer
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  79. Apr 2023
  80. aacrjournals.org aacrjournals.org
    N6-Methyladenosine RNA Modifications Regulate the Response to Platinum through Nicotinamide N-methyltransferase
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  81. Mar 2023
  82. www.sciencedirect.com www.sciencedirect.com
    Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation
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    Matrin3 regulates mitotic spindle dynamics by controlling alternative splicing of CDC14B
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    In vivo RNA-seq and ChIP-seq analyses show an obligatory role for the C terminus of p53 in conferring tissue-specific radiation sensitivity
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    FAM193A is a positive regulator of p53 activity
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive characterization of the embryonic factor LEUTX
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  87. Feb 2023
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 N protein mediates intercellular nucleic acid dispersion, a feature reduced in Omicron
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  90. Jan 2023
  91. www.sciencedirect.com www.sciencedirect.com
    EKLF/Klf1 regulates erythroid transcription by its pioneering activity and selective control of RNA Pol II pause-release
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    Resurrection of endogenous retroviruses during aging reinforces senescence
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  93. Dec 2022
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    β-Defensin 19/119 mediates sperm chemotaxis and is associated with idiopathic infertility
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    Crosstalk between pro-survival sphingolipid metabolism and complement signaling induces inflammasome-mediated tumor metastasis
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Targeting of Cdc42 GTPase in regulatory T cells unleashes antitumor T-cell immunity
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    Tim-4 reprograms cholesterol metabolism to suppress antiviral innate immunity by disturbing the Insig1-SCAP interaction in macrophages
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  98. Nov 2022
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    The oncogenic JAG1 intracellular domain is a transcriptional cofactor that acts in concert with DDX17/SMAD3/TGIF2
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  100. Oct 2022
  101. www.nature.com www.nature.com
    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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    nature.com/articles/s41467-022-33749-0
  102. Sep 2022
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    Targeting the MYC interaction network in B-cell lymphoma via histone deacetylase 6 inhibition
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      DOI: 10.1038/s41388-022-02450-3

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  104. Aug 2022
  105. www.sciencedirect.com www.sciencedirect.com
    ABL kinases regulate translation in HER2+ cells through Y-box-binding protein 1 to facilitate colonization of the brain
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    sciencedirect.com/science/article/pii/S2211124722010865
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    Aerobic glycolysis promotes tumor immune evasion by hexokinase2-mediated phosphorylation of IκBα
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    sciencedirect.com/science/article/pii/S155041312200345X
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    Dual control of formin-nucleated actin assembly by the chromatin and ER in mouse oocytes
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    sciencedirect.com/science/article/pii/S0960982222012076
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    Neuroinflammatory disease disrupts the blood-CNS barrier via crosstalk between proinflammatory and endothelial-to-mesenchymal-transition signaling
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    TOP1 CAD-seq: A protocol to map catalytically engaged topoisomerase 1 in human cells
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  110. Jun 2022
  111. 52.53.155.43 52.53.155.43
    mcr-21-1039-html.html
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  112. www.sciencedirect.com www.sciencedirect.com
    Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation
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    Condensates induced by transcription inhibition localize active chromatin to nucleoli
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    Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids
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  115. May 2022
  116. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Identification and characterization of a special type of subnuclear structure: AGGF1-coated paraspeckles
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    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
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  119. Apr 2022
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    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
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  122. Mar 2022
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    Mucus sialylation determines intestinal host-commensal homeostasis
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    Selective YAP activation in Procr cells is essential for ovarian stem/progenitor expansion and epithelium repair
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    STAT3-mediated allelic imbalance of novel genetic variant rs1047643 and B cell specific super-enhancer in association with systemic lupus erythematosus
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  126. www.sciencedirect.com www.sciencedirect.com
    Lipid flippase dysfunction as a therapeutic target for endosomal anomalies in Alzheimer’s disease
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  127. Feb 2022
  128. www.sciencedirect.com www.sciencedirect.com
    A FBXO7/EYA2-SCFFBXW7 axis promotes AXL-mediated maintenance of mesenchymal and immune evasion phenotypes of cancer cells
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  129. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TBK1-METTL3 axis facilitates antiviral immunity
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    Co-adaptor driven assembly of a CUL3 E3 ligase complex
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    Angiopoietin-2-induced lymphatic endothelial cell migration drives lymphangiogenesis via the β1 integrin-RhoA-formin axis
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  132. Jan 2022
  133. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Histone deacetylase HDAC2 regulates microRNA-125a expression in neuroblastoma
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  134. Dec 2021
  135. www.sciencedirect.com www.sciencedirect.com
    IFI16 inhibits DNA repair that potentiates type-I interferon-induced antitumor effects in triple negative breast cancer
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  136. academic.oup.com academic.oup.com
    A novel CARM1-HuR axis involved in muscle differentiation and plasticity misregulated in spinal muscular atrophy
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    academic.oup.com/hmg/advance-article/doi/10.1093/hmg/ddab333/6428333
  137. academic.oup.com academic.oup.com
    Downregulation Of Dihydrotestosterone And Estradiol Levels By Hexim1
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  138. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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  139. Nov 2021
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Interactome analysis illustrates diverse gene regulatory processes associated with LIN28A in human iPS cell-derived neural progenitor cells
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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  142. Oct 2021
  143. www.sciencedirect.com www.sciencedirect.com
    Mitophagy antagonism by ZIKV reveals Ajuba as a regulator of PINK1 signaling, PKR-dependent inflammation, and viral invasion of tissues
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  144. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deiodinase-3 is a thyrostat to regulate podocyte homeostasis
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    Increased ACTL6A occupancy within mSWI/SNF chromatin remodelers drives human squamous cell carcinoma
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  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NRF3 upregulates gene expression in SREBP2-dependent mevalonate pathway with cholesterol uptake and lipogenesis inhibition
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    DRAK2 aggravates nonalcoholic fatty liver disease progression through SRSF6-associated RNA alternative splicing
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  149. Sep 2021
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    PBRM1 loss in kidney cancer unbalances the proximal tubule master transcription factor hub to repress proximal tubule differentiation
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    The thermogenic activity of adjacent adipocytes fuels the progression of ccRCC and compromises anti-tumor therapeutic efficacy
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Postn Rescues Myogenesis Defects in Myotonic Dystrophy Type 1 Myoblast Model
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      DOI: 10.3389/fcell.2021.710112

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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASCL1, NKX2-1, and PROX1 co-regulate subtype-specific genes in small-cell lung cancer
    1
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  154. Aug 2021
  155. www.sciencedirect.com www.sciencedirect.com
    Establishment of a second generation homozygous CRISPRa human induced pluripotent stem cell (hiPSC) line for enhanced levels of endogenous gene activation
    1
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      RRID:AB_737182

      DOI: 10.1016/j.scr.2021.102518

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    sciencedirect.com/science/article/pii/S1873506121003652
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    Tracing the evolutionary history of Ca2+-signaling modulation by human Bcl-2: Insights from the Capsaspora owczarzaki IP3 receptor ortholog
    1
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      sc-2025

      DOI: 10.1016/j.bbamcr.2021.119121

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  157. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sex and brain region specific regulation of serotonin transporter activity in synaptosomes in guanine nucleotide-binding protein G(q) alpha knockout mice
    1
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      RRID:AB_737182

      DOI: 10.1111/jnc.15482

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15482
  158. www.sciencedirect.com www.sciencedirect.com
    The non-canonical target PARP16 contributes to polypharmacology of the PARP inhibitor talazoparib and its synergy with WEE1 inhibitors
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      RRID:AB_737182

      DOI: 10.1016/j.chembiol.2021.07.008

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    sciencedirect.com/science/article/pii/S2451945621003482
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      RRID:AB_737182

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    ncbi.nlm.nih.gov/pmc/articles/PMC6482433/
  160. www.sciencedirect.com www.sciencedirect.com
    Transcriptional Circuit Fragility Influences HIV Proviral Fate
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    sciencedirect.com/science/article/pii/S2211124719303146
  161. elifesciences.org elifesciences.org
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  162. www.sciencedirect.com www.sciencedirect.com
    UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors
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      DOI: 10.1016/j.cell.2018.11.024

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    sciencedirect.com/science/article/pii/S0092867418315162
  163. www.sciencedirect.com www.sciencedirect.com
    Perturbation of Iron Metabolism by Cisplatin through Inhibition of Iron Regulatory Protein 2
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC6251307/
  165. www.sciencedirect.com www.sciencedirect.com
    FBF1 deficiency promotes beiging and healthy expansion of white adipose tissue
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    SMC complexes are guarded by the SUMO protease Ulp2 against SUMO-chain-mediated turnover
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  168. www.cell.com www.cell.com
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    cell.com/molecular-cell/abstract/S1097-2765(17)30053-9
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    cell.com/cell-reports/abstract/S2211-1247(18)31443-8
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    SRC-3 Coactivator Governs Dynamic Estrogen-Induced Chromatin Looping Interactions during Transcription
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  171. Jul 2021
  172. www.nature.com www.nature.com
    Regulation of the endosomal SNX27-retromer by OTULIN
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    1. scibot 30 Jul 2021
      anti-normal mouse IgG

      DOI: 10.1038/s41467-019-12309-z

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    nature.com/articles/s41467-019-12309-z
  173. www.embopress.org www.embopress.org
    Dual function of VGLL4 in muscle regeneration
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    1. scibot 30 Jul 2021
      mouse IgG

      DOI: 10.15252/embj.2018101051

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  174. www.embopress.org www.embopress.org
    CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling
    1
    1. scibot 30 Jul 2021
      normal mouse IgG

      DOI: 10.15252/embr.201948058

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  175. academic.oup.com academic.oup.com
    Primary Sertoli cell cultures from adult mice have different properties from those derived from 20-day-old animals
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      RRID:AB_737182

      DOI: 10.1210/endocr/bqz020

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    academic.oup.com/endo/article/161/1/bqz020/5626381
  176. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.1016/j.molcel.2018.08.004

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    ncbi.nlm.nih.gov/pmc/articles/PMC6162343/
  177. www.sciencedirect.com www.sciencedirect.com
    Establishment of two homozygous CRISPR interference (CRISPRi) knock-in human induced pluripotent stem cell (hiPSC) lines for titratable endogenous gene repression
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      RRID:AB_737182

      DOI: 10.1016/j.scr.2021.102473

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    Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling
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      RRID:AB_737182

      DOI: 10.1016/j.ccell.2018.11.016

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  179. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Pink1 regulates FKBP5 interaction with AKT/PHLPP and protects neurons from neurotoxin stress induced by MPP+
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      RRID: AB_737182

      DOI: 10.1111/jnc.14683

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14683
  180. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts
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      RRID:AB_737182

      DOI: 10.1113/JP277618

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  181. www.cell.com www.cell.com
    GTF2E2 Mutations Destabilize the General Transcription Factor Complex TFIIE in Individuals with DNA Repair-Proficient Trichothiodystrophy
    2
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      AB_737182

      DOI: 10.1016/j.ajhg.2016.02.008

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      AB_737182

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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myocardin-related transcription factor and serum response factor regulate cilium turnover by both transcriptional and local mechanisms
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      RRID:AB_737182

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  183. www.sciencedirect.com www.sciencedirect.com
    Site-specific O-GlcNAcylation of Psme3 maintains mouse stem cell pluripotency by impairing P-body homeostasis
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2021.109361

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    The Mediator subunit MED20 organizes the early adipogenic complex to promote development of adipose tissues and diet-induced obesity
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      RRID:AB_737182

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    sciencedirect.com/science/article/pii/S2211124721006902
  185. Jun 2021
  186. www.sciencedirect.com www.sciencedirect.com
    TMBIM1 is an inhibitor of adipogenesis and its depletion promotes adipocyte hyperplasia and improves obesity-related metabolic disease
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      RRID:AB_737182

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  187. May 2021
  188. www.sciencedirect.com www.sciencedirect.com
    Pluripotent stem cell-derived endometrial stromal fibroblasts in a cyclic, hormone-responsive, coculture model of human decidua
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    1. scibot 19 May 2021
      RRID:AB_737182

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway
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      RRID:AB_737182

      DOI: 10.7554/eLife.50346

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  190. www.sciencedirect.com www.sciencedirect.com
    Unique Immune Cell Coactivators Specify Locus Control Region Function and Cell Stage
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      RRID:AB_737182

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    sciencedirect.com/science/article/pii/S1097276520307437
  191. www.sciencedirect.com www.sciencedirect.com
    Translational Repression of G3BP in Cancer and Germ Cells Suppresses Stress Granules and Enhances Stress Tolerance
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    sciencedirect.com/science/article/pii/S1097276520304664
  192. www.sciencedirect.com www.sciencedirect.com
    Ubiquitin-dependent remodeling of the actin cytoskeleton drives cell fusion
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  193. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Genome‐Wide Estrogen Receptor β Chromatin Binding in Human Colon Cancer Cells Reveals its Tumor Suppressor Activity
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      RRID:AB_737182

      DOI: 10.1002/ijc.33573

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    onlinelibrary.wiley.com/doi/10.1002/ijc.33573
  194. www.sciencedirect.com www.sciencedirect.com
    Endogenous Retrovirus-Derived lncRNA BANCR Promotes Cardiomyocyte Migration in Humans and Non-human Primates
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      RRID:AB_737182

      DOI: 10.1016/j.devcel.2020.07.006

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    SAS-6 Association with γ-Tubulin Ring Complex Is Required for Centriole Duplication in Human Cells
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      RRID:AB_737182

      DOI: 10.1016/j.cub.2020.04.036

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    sciencedirect.com/science/article/pii/S0960982220305509
  196. Apr 2021
  197. www.sciencedirect.com www.sciencedirect.com
    Elevation of JAML Promotes Diabetic Kidney Disease by Modulating Podocyte Lipid Metabolism
    1
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      RRID:AB_737182

      DOI: 10.1016/j.cmet.2020.10.019

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    sciencedirect.com/science/article/pii/S1550413120305520
  198. www.sciencedirect.com www.sciencedirect.com
    The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development
    1
    1. scibot 29 Apr 2021
      Normal mouse IgG

      DOI: 10.1016/j.cmet.2020.05.008

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  199. www.sciencedirect.com www.sciencedirect.com
    Upregulation of Antioxidant Capacity and Nucleotide Precursor Availability Suffices for Oncogenic Transformation
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      RRID:AB_737182

      DOI: 10.1016/j.cmet.2020.10.002

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    Coordinate regulation of the senescent state by selective autophagy
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      RRID:AB_737182

      DOI: 10.1016/j.devcel.2021.04.008

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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Elevated CXorf67 Expression in PFA Ependymomas Suppresses DNA Repair and Sensitizes to PARP Inhibitors
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      RRID:AB_737182

      DOI: 10.1016/j.ccell.2020.10.009

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    ncbi.nlm.nih.gov/pmc/articles/PMC8455074/
  202. www.sciencedirect.com www.sciencedirect.com
    Cholesterol Pathway Inhibition Induces TGF-β Signaling to Promote Basal Differentiation in Pancreatic Cancer
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      DOI: 10.1016/j.ccell.2020.08.015

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  203. www.sciencedirect.com www.sciencedirect.com
    PKCλ/ι Loss Induces Autophagy, Oxidative Phosphorylation, and NRF2 to Promote Liver Cancer Progression
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      RRID:AB_737182

      DOI: 10.1016/j.ccell.2020.05.018

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen Receptor Beta Influences the Inflammatory p65 Cistrome in Colon Cancer Cells
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      AB_737182

      DOI: 10.3389/fendo.2021.650625

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  205. www.sciencedirect.com www.sciencedirect.com
    A selective p53 activator and anticancer agent to improve colorectal cancer therapy
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2021.108982

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    PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK
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      DOI: 10.1016/j.celrep.2021.108928

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  207. Mar 2021
  208. www.sciencedirect.com www.sciencedirect.com
    Centromeric chromatin integrity is compromised by loss of Cdk5rap2, a transcriptional activator of CENP-A
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      normal IgG

      DOI: 10.1016/j.biopha.2021.111463

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    sciencedirect.com/science/article/pii/S0753332221002481
  209. Feb 2021
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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      RRID:AB_737182

      DOI: 10.1016/j.cmet.2020.12.011

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    FBXO44 promotes DNA replication-coupled repetitive element silencing in cancer cells
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      RRID:AB_737182

      DOI: 10.1016/j.cell.2020.11.042

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  212. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways
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      RRID:AB_737182

      DOI: 10.1111/bph.15261

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  213. www.cell.com www.cell.com
    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
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    1. scibot 26 Feb 2021
      RRID:AB_737182

      DOI: 10.1016/j.devcel.2020.05.031

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    cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
  214. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serotonin signaling by maternal neurons upon stress ensures progeny survival
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      RRID:AB_737182

      DOI: 10.7554/eLife.55246

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  215. www.sciencedirect.com www.sciencedirect.com
    Cancer-associated exportin-6 upregulation inhibits the transcriptionally repressive and anticancer effects of nuclear profilin-1
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2021.108749

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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bach1-induced suppression of angiogenesis is dependent on the BTB domain
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      AB_737182

      DOI: 10.1016/j.ebiom.2019.102617

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  217. elifesciences.org elifesciences.org
    Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice
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      RRID:AB_737182

      DOI: 10.7554/eLife.62174

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  218. Jan 2021
  219. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    G3BPs tether the TSC complex to lysosomes and suppress mTORC1 signaling
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      RRID:AB_737182

      DOI: 10.1016/j.cell.2020.12.024

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  220. www.sciencedirect.com www.sciencedirect.com
    Zinc Finger Protein SALL4 Functions through an AT-Rich Motif to Regulate Gene Expression
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2020.108574

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  221. Dec 2020
  222. link.springer.com link.springer.com
    Vagal afferent fibers contribute to the anti-inflammatory reactions by vagus nerve stimulation in concanavalin A model of hepatitis in rats
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    1. scibot 07 Dec 2020
      RRID:AB_737182

      DOI: 10.1186/s10020-020-00247-2

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    link.springer.com/article/10.1186/s10020-020-00247-2
  223. Nov 2020
  224. www.nature.com www.nature.com
    Expression of a novel brain specific isoform of C3G is regulated during development
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      RRID:AB_737182

      DOI: 10.1038/s41598-020-75813-z

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  225. Oct 2020
  226. www.sciencedirect.com www.sciencedirect.com
    A Regulation Loop between YAP and NR4A1 Balances Cell Proliferation and Apoptosis
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2020.108284

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  227. www.cell.com www.cell.com
    Matrix Rigidity Controls Epithelial-Mesenchymal Plasticity and Tumor Metastasis via a Mechanoresponsive EPHA2/LYN Complex
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      RRID: AB_737182

      DOI: 10.1016/j.devcel.2020.05.031

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    cell.com/developmental-cell/abstract/S1534-5807(20)30420-2
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    Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae
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      AB_737182

      DOI: 10.1016/j.jss.2020.08.071

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  229. Sep 2020
  230. www.sciencedirect.com www.sciencedirect.com
    Transcription Dynamics Regulate Poly(A) Tails and Expression of the RNA Degradation Machinery to Balance mRNA Levels
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      RRID:AB_737182

      DOI: 10.1016/j.molcel.2020.03.022

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  231. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ELT‐2 promotes O‐GlcNAc transferase OGT‐1 expression to modulate Caenorhabditis elegans lifespan
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      RRID:AB_737182

      DOI: 10.1002/jcb.29817

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    Generation of homozygous CRISPRa human induced pluripotent stem cell (hiPSC) lines for sustained endogenous gene activation
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      RRID:AB_737182

      DOI: 10.1016/j.scr.2020.101944

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    MYC Regulation of D2HGDH and L2HGDH Influences the Epigenome and Epitranscriptome
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      RRID:AB_737182

      DOI: 10.1016/j.chembiol.2020.02.002

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    Dysregulated Expression of the Nuclear Exosome Targeting Complex Component Rbm7 in Nonhematopoietic Cells Licenses the Development of Fibrosis
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      RRID:AB_737182

      DOI: 10.1016/j.immuni.2020.02.007

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    CBFβ-SMMHC Affects Genome-wide Polycomb Repressive Complex 1 Activity in Acute Myeloid Leukemia
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2019.12.026

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    ADAR1 Facilitates KSHV Lytic Reactivation by Modulating the RLR-Dependent Signaling Pathway
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      RRID:AB_737182

      DOI: 10.1016/j.celrep.2020.107564

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    Lats1/2 Sustain Intestinal Stem Cells and Wnt Activation through TEAD-Dependent and Independent Transcription
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      RRID:AB_737182

      DOI: 10.1016/j.stem.2020.03.002

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    BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain
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      RRID:AB_737182

      DOI: 10.1016/j.cels.2020.03.003

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    A Cancer-Specific Ubiquitin Ligase Drives mRNA Alternative Polyadenylation by Ubiquitinating the mRNA 3′ End Processing Complex
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      RRID:AB_737182

      DOI: 10.1016/j.molcel.2019.12.022

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