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Nov 2022
www.cell.com www.cell.com

Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity

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1. scibot 10 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111497
  
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cell.com/cell-reports/abstract/S2211-1247(22)01347-X
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ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation

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1. scibot 08 Nov 2022
  
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  DOI: 10.1016/j.molcel.2022.10.017
  
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cell.com/molecular-cell/fulltext/S1097-2765(22)01017-6
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The target antigen determines the mechanism of acquired resistance to T cell-based therapies

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1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.celrep.2022.111430
  
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sciencedirect.com/science/article/pii/S2211124722012712
Oct 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1

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1. scibot 27 Oct 2022
  
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  DOI: 10.7554/eLife.80014
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9592085/
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Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation

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1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.celrep.2022.111555
  
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sciencedirect.com/science/article/pii/S2211124722014115
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The Global Protein-RNA Interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function

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1. scibot 14 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105205
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9550651/
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BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation

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1. scibot 12 Oct 2022
  
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  DOI: 10.1128/jvi.02028-21
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9044952/
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KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice

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1. scibot 11 Oct 2022
  
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  DOI: 10.1016/j.devcel.2022.09.007
  
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sciencedirect.com/science/article/pii/S1534580722006372
Sep 2022
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ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains

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1. scibot 29 Sep 2022
  
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  DOI: 10.1016/j.devcel.2022.09.004
  
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sciencedirect.com/science/article/pii/S1534580722006347
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Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor

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1. scibot 27 Sep 2022
  
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  AB_772210
  
  DOI: 10.3390/ijms231810659
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9503126/
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Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover

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1. scibot 16 Sep 2022
  
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  DOI: 10.1016/j.molcel.2022.08.018
  
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sciencedirect.com/science/article/pii/S1097276522008073
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In vivo characterization of Drosophila golgins reveals redundancy and plasticity of vesicle capture at the Golgi apparatus

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1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.cub.2022.08.054
  
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sciencedirect.com/science/article/pii/S0960982222013768
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Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation

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1. scibot 15 Sep 2022
  
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  DOI: 10.1016/j.celrep.2022.111345
  
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sciencedirect.com/science/article/pii/S2211124722011731
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A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer

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1. scibot 11 Sep 2022
  
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  DOI: 10.1016/j.crmeth.2022.100289
  
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sciencedirect.com/science/article/pii/S2667237522001710
www.nature.com www.nature.com

A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice

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1. scibot 10 Sep 2022
  
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  DOI: 10.1038/s42003-022-03917-5
  
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nature.com/articles/s42003-022-03917-5
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Sublethal cytochrome c release generates drug-tolerant persister cells

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1. scibot 03 Sep 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.cell.2022.07.025
  
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sciencedirect.com/science/article/pii/S0092867422009783
Aug 2022
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CRISPR engineered mouse embryonic stem cells with Sox2-tdTomato and Gata6-GFP knock-in for endoderm differentiation

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1. scibot 27 Aug 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.scr.2022.102900
  
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sciencedirect.com/science/article/pii/S1873506122002495
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A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma

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1. scibot 22 Aug 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.ccell.2022.07.012
  
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sciencedirect.com/science/article/pii/S1535610822003257
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SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production

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1. scibot 02 Aug 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.isci.2022.104759
  
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sciencedirect.com/science/article/pii/S2589004222010318
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS

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1. scibot 27 Jul 2022
  
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  RRID:AB_772210
  
  DOI: 10.15252/embj.2021109217
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9289529/
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Mapping of STB/HAP1 immunoreactivity in the mouse brainstem and its relationships with choline acetyltransferase, with special emphasis on cranial nerve motor and preganglionic autonomic nuclei

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1. scibot 27 Jul 2022
  
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  RRID:AB_772210GE
  
  DOI: 10.1016/j.neuroscience.2022.07.016
  
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sciencedirect.com/science/article/pii/S0306452222003694
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Guiding ATR and PARP inhibitor combinationswith chemogenomic screens

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1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111081
  
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sciencedirect.com/science/article/pii/S2211124722008798
onlinelibrary.wiley.com onlinelibrary.wiley.com

Oral Cancer Cells Release Vesicles that Cause Pain

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1. scibot 12 Jul 2022
  
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  RRID:AB_772210
  
  DOI: 10.1002/adbi.202200073
  
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onlinelibrary.wiley.com/doi/10.1002/adbi.202200073
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The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex

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1. scibot 06 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9213009/
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Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells

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1. scibot 01 Jul 2022
  
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  RRID:AB_772210
  
  DOI: 10.1007/s11010-022-04504-2
  
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link.springer.com/article/10.1007/s11010-022-04504-2
Jun 2022
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Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.crmeth.2022.100235
  
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sciencedirect.com/science/article/pii/S2667237522001047
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Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.009
  
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sciencedirect.com/science/article/pii/S245194562200201X
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Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells

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1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.chembiol.2022.05.006
  
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sciencedirect.com/science/article/pii/S2451945622001982
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CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development

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1. scibot 15 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110957
  
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sciencedirect.com/science/article/pii/S2211124722007392
elifesciences.org elifesciences.org

METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance

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1. scibot 11 Jun 2022
  
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  DOI: 10.7554/eLife.72780
  
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elifesciences.org/articles/72780
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Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex

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1. scibot 10 Jun 2022
  
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  DOI: 10.1016/j.cell.2022.04.016
  
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sciencedirect.com/science/article/pii/S0092867422004639
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Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones

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1. scibot 09 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110918
  
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sciencedirect.com/science/article/pii/S2211124722006957
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Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine

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1. scibot 09 Jun 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.molcel.2022.05.016
  
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sciencedirect.com/science/article/pii/S109727652200483X
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Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion

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1. scibot 02 Jun 2022
  
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  AB_772210
  
  DOI: 10.1016/j.cub.2022.05.019
  
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sciencedirect.com/science/article/pii/S0960982222007783
May 2022
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Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events

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1. scibot 26 May 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.isci.2022.104368
  
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sciencedirect.com/science/article/pii/S2589004222006393
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Redox-sensitive E2 Rad6 controls cellular response to oxidative stress via K63-linked ubiquitination of ribosomes

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1. scibot 26 May 2022
  
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  RRID:AB_772210
  
  DOI: 10.1016/j.celrep.2022.110860
  
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The epilepsy-associated protein PCDH19 undergoes NMDA receptor-dependent proteolytic cleavage and regulates the expression of immediate-early genes

1
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Postnatal expression of cell cycle promoter Fam64a causes heart dysfunction by inhibiting cardiomyocyte differentiation through repression of Klf15

1
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Xist-mediated silencing requires additive functions of SPEN and Polycomb together with differentiation-dependent recruitment of SmcHD1

1
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Defining the Skeletal Myogenic Lineage in Human Pluripotent Stem Cell-Derived Teratomas

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Concurrent Inhibition of ERK and Farnesyltransferase Suppresses the Growth of HRAS Mutant Head and Neck Squamous Cell Carcinoma

1
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Canonical Bone Morphogenetic Protein Signaling Regulates Expression of Aquaporin-4 and Its Anchoring Complex in Mouse Astrocytes

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Retinoic acid-induced protein 14 controls dendritic spine dynamics associated with depressive-like behaviors

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The oncogene-dependent resistance to reprogramming unveils cancer therapeutic targets

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Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs

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Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization

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Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy

1
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Preclinical stress originates in the rat optic nerve head during development of autoimmune optic neuritis

1
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Self-incompatibility requires GPI anchor remodeling by the poppy PGAP1 ortholog HLD1

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The mTOR chromatin-bound interactome in prostate cancer

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MYCT1 alters the glycogen shunt by regulating selective translation of RACK1-mediated enzymes

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The RNA helicase DHX16 recognizes specific viral RNA to trigger RIG-I-dependent innate antiviral immunity

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MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

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Gut microbial trimethylamine is elevated in alcohol-associated hepatitis and contributes to ethanol-induced liver injury in mice

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Deficiency of Mesencephalic Astrocyte-derived Neurotrophic Factor Affects Neurogenesis in Mouse Brain

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The anti-aging protein Klotho affects early postnatal myogenesis by downregulating Jmjd3 and the canonical Wnt pathway

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  DOI: 10.1096/fj.202101298R
  
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Ligand-mediated PAI-1 inhibition in a mouse model of peritoneal carcinomatosis

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Mechanistic impact of oligomer poisoning by dominant-negative CARD11 variants

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ROPGAP-dependent interaction between brassinosteroid and ROP2-GTPase signaling controls pavement cell shape in Arabidopsis

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Analysis of Neutralization Titers against SARS-CoV-2 in Health-Care Workers Vaccinated with Prime-Boost mRNA–mRNA or Vector–mRNA COVID-19 Vaccines

1
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Compartmentalized control of Cdk1 drives mitotic spindle assembly

1
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MYC amplifies gene expression through global changes in transcription factor dynamics

1
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  DOI: 10.1016/j.celrep.2021.110292
  
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High-grade ovarian cancer associated H/ACA snoRNAs promote cancer cell proliferation and survival

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Tissue differences in the exosomal/small extracellular vesicle proteome and their potential as indicators of altered tissue metabolism

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  DOI: 10.1016/j.celrep.2021.110277
  
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Dec 2021
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Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

1
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Conserved and divergent features of neuronal CaMKII holoenzyme structure, function, and high-order assembly

1
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  DOI: 10.1016/j.celrep.2021.110168
  
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Closantel is an allosteric inhibitor of human Taspase1

1
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  DOI: 10.1016/j.isci.2021.103524
  
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Mitochondrial complex I inhibitors suppress tumor growth through concomitant acidification of the intra- and extracellular environment

1
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Disruption of Circadian Rhythms by Ambient Light during Neurodevelopment Leads to Autistic-like Molecular and Behavioral Alterations in Adult Mice

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Matrix Metalloproteinases in Human Decidualized Endometrial Stromal Cells

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  DOI: 10.3390/cimb43030146
  
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Nov 2021
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MYCN recruits the nuclear exosome complex to RNA polymerase II to prevent transcription-replication conflicts

1
1. scibot 30 Nov 2021
  
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Microbial regulation of hexokinase 2 links mitochondrial metabolism and cell death in colitis

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The Y14-p53 regulatory circuit in megakaryocyte differentiation and thrombocytopenia

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Transcriptional regulation of LGALS9 by HAND2 and FOXO1 in human endometrial stromal cells in women with regular cycles

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The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability

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Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia

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Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub

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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

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Controlling tissue patterning by translational regulation of signaling transcripts through the core translation factor eIF3c

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Global characterization of macrophage polarization mechanisms and identification of M2-type polarization inhibitors

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Biochemical approach for isolation of polyadenylated RNAs with bound proteins from yeast

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Cross talk between the upstream exon-intron junction and Prp2 facilitates splicing of non-consensus introns

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Schlafen 11 expression in human acute leukemia cells with gain-of-function mutations in the interferon-JAK signaling pathway

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Characterization of six CaMKIIα variants found in patients with schizophrenia

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GluN2B S1303 phosphorylation by CaMKII or DAPK1: no indication for involvement in ischemia or LTP

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Neuronal XRN1 is required for maintenance of whole-body metabolic homeostasis

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S-acylation controls SARS-CoV-2 membrane lipid organization and enhances infectivity

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GABAB receptor signaling in the caudate putamen is involved in binge-like consumption during a high fat diet in mice

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Preclinical and Clinical Characterization of Fibroblast-derived Neuregulin-1 on Trastuzumab and Pertuzumab Activity in HER2-positive Breast Cancer

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Pericyte Insulin Receptors Modulate Retinal Vascular Remodeling and Endothelial Angiopoietin Signaling

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Structure and dynamics of the chromatin remodeler ALC1 bound to a PARylated nucleosome

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Optimizing metastatic-cascade-dependent Rac1 targeting in breast cancer: Guidance using optical window intravital FRET imaging

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Cocaine shifts dopamine D2 receptor sensitivity to gate conditioned behaviors

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Oligodendrocytes enhance axonal energy metabolism by deacetylation of mitochondrial proteins through transcellular delivery of SIRT2

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Controlled lipid β-oxidation and carnitine biosynthesis by a vitamin D metabolite

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Late adolescence mortality in mice with brain-specific deletion of the volume-regulated anion channel subunit LRRC8A

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The Integrity of the HMR complex is necessary for centromeric binding and reproductive isolation in Drosophila

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Glucagon-like peptide-1 receptor controls exocytosis in chromaffin cells by increasing full-fusion events

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Neutralisation titres against SARS-CoV-2 are sustained 6 months after onset of symptoms in individuals with mild COVID-19

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CD63-mediated cloaking of VEGF in small extracellular vesicles contributes to anti-VEGF therapy resistance

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Non-microtubule tubulin-based backbone and subordinate components of postsynaptic density lattices

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The role of mitochondrial apoptotic pathway in islet amyloid-induced β-cell death

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The non-canonical target PARP16 contributes to polypharmacology of the PARP inhibitor talazoparib and its synergy with WEE1 inhibitors

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Untitled document

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Untitled document

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Untitled document

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Comparative Flavivirus-Host Protein Interaction Mapping Reveals Mechanisms of Dengue and Zika Virus Pathogenesis

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Cyclosporine H Overcomes Innate Immune Restrictions to Improve Lentiviral Transduction and Gene Editing In Human Hematopoietic Stem Cells

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Acetylation of Cytidine in mRNA Promotes Translation Efficiency

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Isthmin-1 is an adipokine that promotes glucose uptake and improves glucose tolerance and hepatic steatosis

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The Soluble Form of LOTUS inhibits Nogo Receptor-Mediated Signaling by Interfering with the Interaction Between Nogo Receptor Type 1 and p75 Neurotrophin Receptor

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Mitochondrial cristae-remodeling protein OPA1 in POMC neurons couples Ca2+ homeostasis with adipose tissue lipolysis

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Decapping Enzyme NUDT12 Partners with BLMH for Cytoplasmic Surveillance of NAD-Capped RNAs

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Replication Study: Melanoma exosomes educate bone marrow progenitor cells toward a pro-metastatic phenotype through MET

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A novel crosslinking protocol stabilizes amyloid β oligomers capable of inducing Alzheimer's‐associated pathologies

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Germline-Encoded Affinity for Cognate Antigen Enables Vaccine Amplification of a Human Broadly Neutralizing Response against Influenza Virus

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Hyaluronan synthesis supports glutamate transporter activity

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Microtubule Tip Tracking by the Spindle and Kinetochore Protein Ska1 Requires Diverse Tubulin-Interacting Surfaces

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Tinagl1 Suppresses Triple-Negative Breast Cancer Progression and Metastasis by Simultaneously Inhibiting Integrin/FAK and EGFR Signaling

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AR Signaling in Prostate Cancer Regulates a Feed-Forward Mechanism of Androgen Synthesis by Way of HSD3B1 Upregulation

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Combined Human Genome-wide RNAi and Metabolite Analyses Identify IMPDH as a Host-Directed Target against Chlamydia Infection

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Transcription-mediated supercoiling regulates genome folding and loop formation

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Tau oligomer induced HMGB1 release contributes to cellular senescence and neuropathology linked to Alzheimer’s disease and frontotemporal dementia

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Depletion of HP1α alters the mechanical properties of MCF7 nuclei

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ERAD components Derlin-1 and Derlin-2 are essential for postnatal brain development and motor function

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Oxidative stress induces coordinated remodeling of RNA-enzyme interactions

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Targeted protein degradation reveals a direct role of SPT6 in RNAPII elongation and termination

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Regulation of NMDA receptor trafficking and gating by activity-dependent CaMKIIα phosphorylation of the GluN2A subunit

1
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Neonatal susceptibility to meningitis results from the immaturity of epithelial barriers and gut microbiota

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Endothelial insulin receptors promote VEGF-A signaling via ERK1/2 and sprouting angiogenesis

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TNIK is a therapeutic target in Lung Squamous Cell Carcinoma and regulates FAK activation through Merlin.

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Intra-vessel heterogeneity establishes enhanced sites of macromolecular leakage downstream of laminin α5

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An Integrated Analysis of the Response of Colorectal Adenocarcinoma Caco-2 Cells to X-Ray Exposure

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Redox feedback regulation of ANAC089 signaling alters seed germination and stress response

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NADK is activated by oncogenic signaling to sustain pancreatic ductal adenocarcinoma

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Extreme deformability of insect cell membranes is governed by phospholipid scrambling

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Reprogramming an energetic AKT-PAK5 axis boosts axon energy supply and facilitates neuron survival and regeneration after injury and ischemia

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Phosphorylation of Collapsin Response Mediator Protein 1 (CRMP1) at Tyrosine 504 residue regulates Semaphorin 3A-induced cortical dendritic growth

1
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Nuclear lipidome is altered in amyotrophic lateral sclerosis: a pilot study

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Signals of pseudo-starvation unveil the amino acid transporter SLC7A11 as key determinant in the control of Treg cell proliferative potential

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Disruption of entire Cables2 locus leads to embryonic lethality by diminished Rps21 gene expression and enhanced p53 pathway

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The Polyglutamine Expansion at the N-Terminal of Huntingtin Protein Modulates the Dynamic Configuration and Phosphorylation of the C-Terminal HEAT Domain

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Derivation of Intermediate Pluripotent Stem Cells Amenable to Primordial Germ Cell Specification

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Inherited DNA Repair Defects Disrupt the Structure and Function of Human Skin

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Androgen affects the dynamics of intrinsic plasticity of pyramidal neurons in the CA1 hippocampal subfield in adolescent male rats

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Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer’s Disease

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SUMOylation of Enzymes and Ion Channels in Sensory Neurons Protects against Metabolic Dysfunction, Neuropathy, and Sensory Loss in Diabetes

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Amino Acids Enhance Polyubiquitination of Rheb and Its Binding to mTORC1 by Blocking Lysosomal ATXN3 Deubiquitinase Activity

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Tumor Interferon Signaling Is Regulated by a lncRNA INCR1 Transcribed from the PD-L1 Locus

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Caspase-8-Dependent Inflammatory Responses Are Controlled by Its Adaptor, FADD, and Necroptosis

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NLR-1/CASPR Anchors F-Actin to Promote Gap Junction Formation

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Phenotypic analysis of a transgenic Drosophila model of Alzheimer’s amyloid-β toxicity

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Caloric Restriction Promotes Immunometabolic Reprogramming Leading to Protection from Tuberculosis

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Generation of a p16 Reporter Mouse and Its Use to Characterize and Target p16high Cells In Vivo

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SGLT2 Inhibition Mediates Protection from Diabetic Kidney Disease by Promoting Ketone Body-Induced mTORC1 Inhibition

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Modeling plasticity and dysplasia of pancreatic ductal organoids derived from human pluripotent stem cells

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An IMiD-inducible degron provides reversible regulation for chimeric antigen receptor expression and activity

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Plant roots employ cell-layer-specific programs to respond to pathogenic and beneficial microbes

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Proteomics of broad deubiquitylase inhibition unmasks redundant enzyme function to reveal substrates and assess enzyme specificity

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Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

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4E-BP2-dependent translation in cerebellar Purkinje cells controls spatial memory but not autism-like behaviors

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Defining and Manipulating B Cell Immunodominance Hierarchies to Elicit Broadly Neutralizing Antibody Responses against Influenza Virus

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1. scibot 27 Apr 2021
  
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  Sheep Anti-IgG-HRP
  
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Site-Specific Incorporation of Genetically Encoded Photo-Crosslinkers Locates the Heteromeric Interface of a GPCR Complex in Living Cells

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  DOI: 10.1016/j.chembiol.2020.07.006
  
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Obesity Shapes Metabolism in the Tumor Microenvironment to Suppress Anti-Tumor Immunity

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  DOI: 10.1016/j.cell.2020.11.009
  
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cell.com/cell/fulltext/S0092-8674(20)31526-9
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Generation of disease-specific and CRISPR/Cas9-mediated gene-corrected iPS cells from a patient with adult progeria Werner syndrome

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Lipid-mediated motor-adaptor sequestration impairs axonal lysosome delivery leading to autophagic stress and dystrophy in Niemann-Pick type C

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1. scibot 20 Apr 2021
  
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  DOI: 10.1016/j.devcel.2021.03.032
  
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Orchestrating aquaporin-4 and connexin-43 expression in brain: Differential roles of α1- and β1-syntrophin

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  DOI: 10.1016/j.bbamem.2021.183616
  
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Social context-dependent singing alters molecular markers of synaptic plasticity signaling in finch basal ganglia Area X

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  DOI: 10.1016/j.bbr.2020.112955
  
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Dissecting the impact of regional identity and the oncogenic role of human-specific NOTCH2NL in an hESC model of H3.3G34R-mutant glioma

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Nanog is a promising chemo‐resistant stemness marker and therapeutic target by iron chelators for esophageal cancer

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  horseradish peroxidase (HRP)‐linked whole sheep
  
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Targeted degradation of transcription factors by TRAFTACs: TRAnscription Factor TArgeting Chimeras

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  DOI: 10.1016/j.chembiol.2021.03.011
  
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CHPG enhances BDNF and myelination in cuprizone‐treated mice through astrocytic metabotropic glutamate receptor 5

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Mar 2021
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The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway

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Feb 2021
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Hepatic Ago2 regulates PPARα for oxidative metabolism linked to glycemic control in obesity and post-bariatric surgery

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Control of replication stress and mitosis in colorectal cancer stem cells through the interplay of PARP1, MRE11 and RAD51

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  DOI: 10.1038/s41418-020-00733-4
  
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Mesoscale Modeling and Single-Nucleosome Tracking Reveal Remodeling of Clutch Folding and Dynamics in Stem Cell Differentiation

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Functional impact of a congenital stationary night blindness type 2 mutation depends on subunit composition of Cav1.4 Ca2+ channels

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  anti-mouse HRP
  
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Fatal Perinatal Mitochondrial Cardiac Failure Caused by Recurrent De Novo Duplications in the ATAD3 Locus

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  DOI: 10.1016/j.medj.2020.06.004
  
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cell.com/med/fulltext/S2666-6340(20)30009-X
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Cryo-EM structures of human ZnT8 in both outward- and inward-facing conformations

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1. scibot 26 Feb 2021
  
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  DOI: 10.7554/eLife.58823
  
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Biphasic Activation of WNT Signaling Facilitates the Derivation of Midbrain Dopamine Neurons from hESCs for Translational Use

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Nogo receptor antagonist LOTUS exerts suppression on axonal growth‐inhibiting receptor PIR‐B

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  DOI: 10.1111/jnc.15013
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15013

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