569 Matching Annotations
  1. Last 7 days
  2. www.sciencedirect.com www.sciencedirect.com
    PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD
    1
    1. scibot 13 Mar 2025
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      DOI: 10.1016/j.neuron.2025.02.005

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    sciencedirect.com/science/article/pii/S0896627325001187
  3. www.sciencedirect.com www.sciencedirect.com
    Engineering mtDNA deletions by reconstituting end joining in human mitochondria
    1
    1. scibot 11 Mar 2025
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      DOI: 10.1016/j.cell.2025.02.009

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    sciencedirect.com/science/article/pii/S0092867425001941
  4. Feb 2025
  5. www.biorxiv.org www.biorxiv.org
    Phosphatase specificity influences phosphorylation timing of CDK substrates during the cell cycle
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    1. scibot 28 Feb 2025
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      DOI: 10.1101/2025.02.21.639482

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    biorxiv.org/content/10.1101/2025.02.21.639482v1
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fusion oncoproteins and cooperating mutations define disease phenotypes in NUP98-rearranged leukemia
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    1. scibot 27 Feb 2025
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      DOI: 10.1101/2025.01.21.25320683

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    pmc.ncbi.nlm.nih.gov/articles/PMC11838931/
  7. www.sciencedirect.com www.sciencedirect.com
    MARIGOLD and MitoCIAO, two searchable compendia to visualize and functionalize protein complexes during mitochondrial remodeling
    1
    1. scibot 25 Feb 2025
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      DOI: 10.1016/j.cmet.2025.01.017

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    sciencedirect.com/science/article/pii/S1550413125000178
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for assessing the clogging of the mitochondrial translocase of the outer membrane by precursor proteins in human cells
    1
    1. scibot 24 Feb 2025
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      DOI: 10.1016/j.xpro.2025.103617

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    pmc.ncbi.nlm.nih.gov/articles/PMC11835637/
  9. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    1. scibot 22 Feb 2025
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      DOI: 10.1111/bph.70007

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70007
  10. elifesciences.org elifesciences.org
    The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis
    1
    1. scibot 08 Feb 2025
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      DOI: 10.7554/eLife.86931

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    elifesciences.org/articles/86931
  11. 52.53.155.43 52.53.155.43
    awaf051-html.html
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    1. scibot 07 Feb 2025
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      DOI: 10.1093/brain/awaf051

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    GUK1 activation is a metabolic liability in lung cancer
    1
    1. scibot 07 Feb 2025
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      DOI: 10.1016/j.cell.2025.01.024

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    sciencedirect.com/science/article/pii/S0092867425000935
  13. Jan 2025
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cholesterol restriction primes antiviral innate immunity via SREBP1-driven noncanonical type I IFNs
    1
    1. scibot 30 Jan 2025
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      DOI: 10.1038/s44319-024-00346-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11772592/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CDKN2A/B homozygous deletion sensitizes IDH-mutant glioma to CDK4/6 inhibition
    1
    1. scibot 25 Jan 2025
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      DOI: 10.1158/1078-0432.CCR-24-0562

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    pmc.ncbi.nlm.nih.gov/articles/PMC11250907/
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Phospho-regulation of ASCL1-mediated chromatin opening during cellular reprogramming
    1
    1. scibot 24 Jan 2025
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      DOI: 10.1242/dev.204329

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    pmc.ncbi.nlm.nih.gov/articles/PMC11664170/
  17. rupress.org rupress.org
    TanGIBLE: A selective probe for evaluating hydrophobicity-exposed defective proteins in live cells
    1
    1. scibot 18 Jan 2025
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      DOI: 10.1083/jcb.202109010

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    rupress.org/jcb/article/224/3/e202109010/277212/TanGIBLE-A-selective-probe-for-evaluating
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Downregulation of semaphorin 4A in keratinocytes reflects the features of non-lesional psoriasis
    1
    1. scibot 04 Jan 2025
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      DOI: 10.7554/eLife.97654

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    pmc.ncbi.nlm.nih.gov/articles/PMC11687936/
  19. Dec 2024
  20. www.sciencedirect.com www.sciencedirect.com
    The Cullin3-Rbx1-KLHL9 E3 ubiquitin ligase complex ubiquitinates Rheb and supports amino acid-induced mTORC1 activation
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115101

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    sciencedirect.com/science/article/pii/S2211124724014529
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    Dual inhibition of BET and EP300 has antitumor activity in undifferentiated pleomorphic sarcomas and synergizes with ferroptosis induction
    1
    1. scibot 17 Dec 2024
      RRID:AB_772

      DOI: 10.1016/j.tranon.2024.102236

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    sciencedirect.com/science/article/pii/S1936523324003620
  22. www.sciencedirect.com www.sciencedirect.com
    A single immunization with intranasal Newcastle disease virus (NDV)-based XBB.1.5 variant vaccine reduces disease and transmission in animals against matched-variant challenge
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    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.vaccine.2024.126586

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    sciencedirect.com/science/article/pii/S0264410X24012684
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    Reduced lung metastasis in endothelial cell-specific transforming growth factor β type II receptor-deficient mice with decreased CD44 expression
    1
    1. scibot 14 Dec 2024
      RRID:AB_772210

      DOI: 10.1016/j.isci.2024.111502

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    sciencedirect.com/science/article/pii/S2589004224027299
  24. www.sciencedirect.com www.sciencedirect.com
    Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway
    1
    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.isci.2024.111457

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    sciencedirect.com/science/article/pii/S2589004224026841
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    DCP1A, a MEK substrate, regulates the self-renewal and differentiation of mouse embryonic stem cells
    1
    1. scibot 14 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115058

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    sciencedirect.com/science/article/pii/S2211124724014098
  26. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-cell analysis reveals host S phase drives large T antigen expression during BK polyomavirus infection
    1
    1. scibot 11 Dec 2024
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      DOI: 10.1371/journal.ppat.1012663

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    pmc.ncbi.nlm.nih.gov/articles/PMC11620372/
  27. 52.53.155.43 52.53.155.43
    1-s2.0-S2589004224027433-main-html.html
    1
    1. scibot 06 Dec 2024
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      DOI: 10.1016/j.isci.2024.111516

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    52.53.155.43/4cd936c6d252d720783f395bd288e7a8753b9204/1-s2.0-S2589004224027433-main-html.html
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
    1
    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.009

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    sciencedirect.com/science/article/pii/S1097276524009146
  29. Nov 2024
  30. www.sciencedirect.com www.sciencedirect.com
    AMPK regulates Bcl2-L-13-mediated mitophagy induction for cardioprotection
    1
    1. scibot 28 Nov 2024
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      DOI: 10.1016/j.celrep.2024.115001

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    sciencedirect.com/science/article/pii/S2211124724013524
  31. www.sciencedirect.com www.sciencedirect.com
    Profound synthetic lethality between SMARCAL1 and FANCM
    1
    1. scibot 17 Nov 2024
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      DOI: 10.1016/j.molcel.2024.10.016

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    sciencedirect.com/science/article/pii/S1097276524008566
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identification of ERAD-dependent degrons for the endoplasmic reticulum lumen
    1
    1. scibot 14 Nov 2024
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      DOI: 10.7554/eLife.89606

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    pmc.ncbi.nlm.nih.gov/articles/PMC11556787/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
    1
    1. scibot 10 Nov 2024
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      DOI: 10.1016/j.isci.2024.111139

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    pmc.ncbi.nlm.nih.gov/articles/PMC11539641/
  34. Sep 2024
  35. www.sciencedirect.com www.sciencedirect.com
    C9orf72 poly-PR forms anisotropic condensates causative of nuclear TDP-43 pathology
    1
    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.isci.2024.110937

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    sciencedirect.com/science/article/pii/S258900422402162X
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Synaptotagmin‐7 enhances calcium‐sensing of chromaffin cell granules and slows discharge of granule cargos
    1
    1. scibot 25 Sep 2024
      RRID:AB_2721110

      DOI: 10.1111/jnc.14986

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14986
  37. academic.oup.com academic.oup.com
    Ghrelin-Induced Sodium Reabsorption is Mediated by PKA and Microtubule-Dependent αE Na C Translocation In Female Rats
    2
    1. scibot 25 Sep 2024
      RRID:AB_772206

      DOI: 10.1210/js.2019-00121

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      DOI: 10.1210/js.2019-00121

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    academic.oup.com/jes/article/3/11/2088/5556717
  38. www.sciencedirect.com www.sciencedirect.com
    Dynamic allostery drives autocrine and paracrine TGF-β signaling
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      DOI: 10.1016/j.cell.2024.08.036

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    sciencedirect.com/science/article/pii/S0092867424009656
  39. www.sciencedirect.com www.sciencedirect.com
    FYVE1/FREE1 is involved in glutamine-responsive TORC1 activation in plants
    1
    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.isci.2024.110814

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    sciencedirect.com/science/article/pii/S258900422402039X
  40. www.sciencedirect.com www.sciencedirect.com
    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
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    1. scibot 10 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114730

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    sciencedirect.com/science/article/pii/S2211124724010817
  41. www.sciencedirect.com www.sciencedirect.com
    The ribosome collision sensor Hel2 functions as preventive quality control in the secretory pathway
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    1. scibot 09 Sep 2024
      RRID:AB_772210

      DOI: 10.1016/j.celrep.2021.108877

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    sciencedirect.com/science/article/pii/S2211124721001911
  42. www.sciencedirect.com www.sciencedirect.com
    Disorder-mediated interactions target proteins to specific condensates
    1
    1. scibot 04 Sep 2024
      RRID:AB_772210

      DOI: 10.1016/j.molcel.2024.08.017

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    sciencedirect.com/science/article/pii/S1097276524006713
  43. Aug 2024
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Knockout of the orphan membrane transporter Slc22a23 leads to a lean and hyperactive phenotype with a small hippocampal volume
    1
    1. scibot 30 Aug 2024
      RRID:AB_772210

      DOI: 10.1371/journal.pone.0309461

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    ncbi.nlm.nih.gov/pmc/articles/PMC11356391/
  45. www.sciencedirect.com www.sciencedirect.com
    Disruption of nuclear speckle integrity dysregulates RNA splicing in C9ORF72-FTD/ALS
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.neuron.2024.07.025

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    sciencedirect.com/science/article/pii/S0896627324005701
  46. www.sciencedirect.com www.sciencedirect.com
    Engineering acyclovir-induced RNA nanodevices for reversible and tunable control of aptamer function
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    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.chembiol.2024.07.017

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    Association with TFIIIC limits MYCN localisation in hubs of active promoters and chromatin accumulation of non-phosphorylated RNA polymerase II
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    Beta-arrestin 1 mediated Src activation via Src SH3 domain revealed by cryo-electron microscopy
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    Differential effect of asparagine and glutamine removal on three adenocarcinoma cell lines
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    Exclusive Characteristics of the p.E555K Dominant-Negative Variant in Autosomal Dominant E47 Deficiency
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  51. Jul 2024
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    An inactivated SARS-CoV-2 vaccine based on a Vero cell culture-adapted high-titer virus confers cross-protection in small animals
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    ATAD1 prevents clogging of TOM and damage caused by un-imported mitochondrial proteins
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    Citrate metabolism controls the senescent microenvironment via the remodeling of pro-inflammatory enhancers
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    Secondary interactions in ubiquitin-binding domains achieve linkage or substrate specificity
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    Disruption of TGF-β signaling pathway is required to mediate effective killing of hepatocellular carcinoma by human iPSC-derived NK cells
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    Dystrophin S3059 phosphorylation partially attenuates denervation atrophy in mouse tibialis anterior muscles
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    Mutation-induced LZTR1 polymerization provokes cardiac pathology in recessive Noonan syndrome
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    Translational control in the spinal cord regulates gene expression and pain hypersensitivity in the chronic phase of neuropathic pain
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    Generation and characterization of inducible KRAB-dCas9 iPSCs from primates for cross-species CRISPRi
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  61. Jun 2024
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    MTFP1 controls mitochondrial fusion to regulate inner membrane quality control and maintain mtDNA levels
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    Intranasal SARS-CoV-2 Omicron variant vaccines elicit humoral and cellular mucosal immunity in female mice
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  64. May 2024
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    RNA quality control factors nucleate Clr4/SUV39H and trigger constitutive heterochromatin assembly
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    Specificity profiling of deubiquitylases against endogenously generated ubiquitin-protein conjugates
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    A conserved site on Ndc80 complex facilitates dynamic recruitment of Mps1 to yeast kinetochores to promote accurate chromosome segregation
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    Microtubule end-on attachment maturation regulates Mps1 association with its kinetochore receptor
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    The RIPK1 death domain restrains ZBP1- and TRIF-mediated cell death and inflammation
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    IL17A Suppresses IGFBP1 in Human Endometrial Stromal Cells
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  73. Apr 2024
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    HSV-1 employs UL56 to antagonize expression and function of cGAMP channels
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    Reversible S-nitrosylation of bZIP67 by peroxiredoxin IIE activity and nitro-fatty acids regulates the plant lipid profile
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    RAD51 separation of function mutation disables replication fork maintenance but preserves DSB repair
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    TRPA5 encodes a thermosensitive ankyrin ion channel receptor in a triatomine insect
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    Zona Glomerulosa–Derived Klotho Modulates Aldosterone Synthase Expression in Young Female Mice
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    A rewiring of DNA replication mediated by MRE11 exonuclease underlies primed-to-naive cell de-differentiation
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    BAI1 localizes AMPA receptors at the cochlear afferent post-synaptic density and is essential for hearing
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  81. Mar 2024
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    A stress sensor, IRE1α, is required for bacterial-exotoxin-induced interleukin-1β production in tissue-resident macrophages
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    Hypoxia-inducible factor 1 recruits FACT and RNF20/40 to mediate histone ubiquitination and transcriptional activation of target genes
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    DNAJB8 oligomerization is mediated by an aromatic-rich motif that is dispensable for substrate activity
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    De novo steroidogenesis in tumor cells drives bone metastasis and osteoclastogenesis
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    TREX2 deficiency suppresses spontaneous and genotoxin-associated mutagenesis
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    SARS-CoV-2 targets ribosomal RNA biogenesis
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  89. Feb 2024
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    Aberrant cortex contractions impact mammalian oocyte quality
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    Circadian Disruption across Lifespan Impairs Glucose Homeostasis and Insulin Sensitivity in Adult Mice
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  92. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EBAG9-deficient mice display decreased bone mineral density with suppressed autophagy
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  94. Jan 2024
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    IL32 downregulation lowers triglycerides and type I collagen in di-lineage human primary liver organoids
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    Decreased nitrosylation of CaMKII causes aging-associated impairments in memory and synaptic plasticity in mice
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    Identification of activity-based biomarkers for early-stage pancreatic tumors in blood using single-molecule enzyme activity screening
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    Pioneer and PRDM transcription factors coordinate bivalent epigenetic states to safeguard cell fate
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FAK Drives Resistance to Therapy in HPV-Negative Head and Neck Cancer in a p53-Dependent Manner
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    The FANCI/FANCD2 complex links DNA damage response to R-loop regulation through SRSF1-mediated mRNA export
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    A SNAI2/CTCF Interaction is Required for NOTCH1 Expression in Rhabdomyosarcoma
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  102. Dec 2023
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    VE-cadherin junction dynamics in initial lymphatic vessels promotes lymph node metastasis
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    Inhibition of lipid synthesis by the HIV integrase strand transfer inhibitor elvitegravir in primary rat oligodendrocyte cultures
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    A protocol to investigate the effects of lncRNAs on in vivo protein-protein interactions using proximity ligation assay
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    TOR inactivation triggers heterochromatin formation in rDNA during glucose starvation
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    ALK inhibitors increase ALK expression and sensitize neuroblastoma cells to ALK.CAR-T cells
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    Streptozotocin-Induced Diabetic Rats Showed a Differential Glycine Receptor Expression in the Spinal Cord: A GlyR Role in Diabetic Neuropathy
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    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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  110. Nov 2023
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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    Deep mutational scanning highlights a role for cytosolic regions in Hrd1 function
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    Therapeutic targeting of EP300/CBP by bromodomain inhibition in hematologic malignancies
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    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
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  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 hijacks a cell damage response, which induces transcription of a more efficient Spike S-acyltransferase
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  118. Oct 2023
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    PAICS ubiquitination recruits UBAP2 to trigger phase separation for purinosome assembly
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    Regulation of STING activity in DNA sensing by ISG15 modification
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    WIP1 is a novel specific target for growth hormone action
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  123. www.nature.com www.nature.com
    SIRT1 is an actionable target to restore p53 function in HPV-associated cancer therapy
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    TERRA R-loops connect and protect sister telomeres in mitosis
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    ASCL1-ERK1/2 Axis: ASCL1 restrains ERK1/2 via the dual specificity phosphatase DUSP6 to promote survival of a subset of neuroendocrine lung cancers
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  126. www.cell.com www.cell.com
    Heterogeneity of perivascular astrocyte endfeet depending on vascular regions in the mouse brain
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  127. Sep 2023
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    Glutamate transporter contribution to retinal ganglion cell vulnerability in a rat model of multiple sclerosis
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    The fruit fly acetyltransferase chameau promotes starvation resilience at the expense of longevity
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    Decreased nitrosylation of CaMKII causes aging-associated impairments in memory and synaptic plasticity in mice
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    Systematic profiling of dominant ubiquitin variants reveals key functional nodes contributing to evolutionary selection
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  132. Jul 2023
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    Aurora A polyubiquitinates the BRCA1-interacting protein OLA1 to promote centrosome maturation
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    Loss of STING in parkin mutant flies suppresses muscle defects and mitochondria damage
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    A p53/LINC00324 positive feedback loop suppresses tumor growth by counteracting SET-mediated transcriptional repression
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    Excitatory neuron-specific suppression of the integrated stress response contributes to autism-related phenotypes in fragile X syndrome
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    Copine-6 is a Ca2+ sensor for activity-induced AMPA receptor exocytosis
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  138. www.cell.com www.cell.com
    Fetal manipulation of maternal metabolism is a critical function of the imprinted Igf2 gene
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  139. www.embopress.org www.embopress.org
    Centrosome amplification fine tunes tubulin acetylation to differentially control intracellular organization
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  140. Jun 2023
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    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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    Breast cancer cell mesenchymal transition and metastasis directed by DAP5/eIF3d-mediated selective mRNA translation
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    Oncogenic IDH mutations increase heterochromatin-related replication stress without impacting homologous recombination
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  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIF4 regulates neuronal morphology and seizure susceptibility via the PARP1 signaling pathway
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  145. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Homeostatic Regulation of Seizure Susceptibility and Cognitive Function by ER Quality Controller Derlin-1 through Maintenance of Adult Neurogenesis
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  147. May 2023
  148. www.sciencedirect.com www.sciencedirect.com
    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    An isoform of the giant protein titin is a master regulator of human T lymphocyte trafficking
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    Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases
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    Generation of a genetically-modified induced pluripotent stem cell line harboring a Noonan syndrome-associated gene variant MRAS p.G23V
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  153. Apr 2023
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    Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases
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    Modular antibodies reveal DNA damage-induced mono-ADP-ribosylation as a second wave of PARP1 signaling
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  156. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    Generation of a genetically-modified induced pluripotent stem cell line harboring an oncogenic gene variant KRAS p.G12V
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    N-acetylcysteine overcomes NF1 loss-driven resistance to PI3Kα inhibition in breast cancer
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  159. Mar 2023
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    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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  162. journals.physiology.org journals.physiology.org
    Sulforaphane attenuates cancer cell-induced atrophy of C2C12 myotubes
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    Several cell-intrinsic effectors drive type I interferon-mediated restriction of HIV-1 in primary CD4+ T cells
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    Identification of an immunodominant region on a group A Streptococcus T-antigen reveals temperature-dependent motion in pili
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  166. Feb 2023
  167. www.sciencedirect.com www.sciencedirect.com
    Loss of C9orf72 perturbs the Ran-GTPase gradient and nucleocytoplasmic transport, generating compositionally diverse Importin β-1 granules
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    IGF-binding proteins secreted by cancer-associated fibroblasts induce context-dependent drug sensitization of lung cancer cells
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    Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control
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    Development of a bispecific DNA-aptamer-based lysosome-targeting chimera for HER2 protein degradation
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    An inactivated SARS-CoV-2 vaccine induced cross-neutralising persisting antibodies and protected upon challenge in small animals
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  172. www.mdpi.com www.mdpi.com
    Asparagine and Glutamine Deprivation Alters Ionizing Radiation Response, Migration and Adhesion of a p53null Colorectal Cancer Cell Line
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    Direct activation of microglia by β-glucosylceramide causes phagocytosis of neurons that exacerbates Gaucher disease
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  174. Jan 2023
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    Seasonal cues act through the circadian clock and pigment-dispersing factor to control EYES ABSENT and downstream physiological changes
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    Protocol for the analysis of double-stranded RNAs in virus-infected insect cells using anti-dsRNA antibodies
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    The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Microbiota-dependent proteolysis of gluten subverts diet-mediated protection against type 1 diabetes
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    Functional partitioning of transcriptional regulators by patterned charge blocks
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  181. Dec 2022
  182. www.sciencedirect.com www.sciencedirect.com
    AKTIP loss is enriched in ERα-positive breast cancer for tumorigenesis and confers endocrine resistance
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  183. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Profiling a single-stranded DNA region within an rDNA segment that affects the loading of bacterial condensin
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Survivin promotes a glycolytic switch in CD4+ T cells by suppressing the transcription of PFKFB3 in rheumatoid arthritis
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  185. Nov 2022
  186. www.cell.com www.cell.com
    Hypothalamic orexin prevents non-alcoholic steatohepatitis and hepatocellular carcinoma in obesity
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    cell.com/cell-reports/abstract/S2211-1247(22)01347-X
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    ATG9A and ATG2A form a heteromeric complex essential for autophagosome formation
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    The target antigen determines the mechanism of acquired resistance to T cell-based therapies
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  189. Oct 2022
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    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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    Structural basis of interleukin-17B receptor in complex with a neutralizing antibody for guiding humanization and affinity maturation
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    The Global Protein-RNA Interaction map of ESRP1 defines a post-transcriptional program that is essential for epithelial cell function
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    BK Polyomavirus Requires the Mismatch Repair Pathway for DNA Damage Response Activation
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    KIF3B promotes a PI3K signaling gradient causing changes in a Shh protein gradient and suppressing polydactyly in mice
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    ER-Golgi-localized proteins TMED2 and TMED10 control the formation of plasma membrane lipid nanodomains
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    Effects of Chronic Kidney Disease on Nanomechanics of the Endothelial Glycocalyx Are Mediated by the Mineralocorticoid Receptor
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    Sensing of individual stalled 80S ribosomes by Fap1 for nonfunctional rRNA turnover
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    In vivo characterization of Drosophila golgins reveals redundancy and plasticity of vesicle capture at the Golgi apparatus
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    Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation
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    A next-generation iPSC-derived forebrain organoid model of tauopathy with tau fibrils by AAV-mediated gene transfer
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    A RUNX-targeted gene switch-off approach modulates the BIRC5/PIF1-p21 pathway and reduces glioblastoma growth in mice
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    Sublethal cytochrome c release generates drug-tolerant persister cells
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  204. Aug 2022
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    CRISPR engineered mouse embryonic stem cells with Sox2-tdTomato and Gata6-GFP knock-in for endoderm differentiation
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    SARS-CoV-2 Delta spike protein enhances the viral fusogenicity and inflammatory cytokine production
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  208. Jul 2022
  209. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Varicella‐Zoster virus ORF9 is an antagonist of the DNA sensor cGAS
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    Mapping of STB/HAP1 immunoreactivity in the mouse brainstem and its relationships with choline acetyltransferase, with special emphasis on cranial nerve motor and preganglionic autonomic nuclei
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    Guiding ATR and PARP inhibitor combinationswith chemogenomic screens
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    Oral Cancer Cells Release Vesicles that Cause Pain
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    The SARS-CoV-2 protein NSP2 impairs the silencing capacity of the human 4EHP-GIGYF2 complex
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    Phloretin inhibits glucose transport and reduces inflammation in human retinal pigment epithelial cells
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  215. Jun 2022
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    Identification of the stress granule transcriptome via RNA-editing in single cells and in vivo
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      DOI: 10.1016/j.crmeth.2022.100235

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    Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses
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    Visualization of the dynamic interaction between nucleosomal histone H3K9 tri-methylation and HP1α chromodomain in living cells
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    CLASP2 safeguards hematopoietic stem cell properties during mouse and fish development
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    METTL18-mediated histidine methylation of RPL3 modulates translation elongation for proteostasis maintenance
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    Structural basis for RNA surveillance by the human nuclear exosome targeting (NEXT) complex
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    Assembly checkpoint of the proteasome regulatory particle is activated by coordinated actions of proteasomal ATPase chaperones
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    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
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  225. May 2022
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    Aβ-induced synaptic impairments require CaMKII activity that is stimulated by indirect signaling events
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