4,927 Matching Annotations
  1. Sep 2026
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Programmable engineered bacteria manipulate metabolism and remodel the TME in situ for enhancing adoptive cell therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13555542/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genome-scale perturb-seq in primary human CD4+ T cells maps context-specific regulators of T cell programs and human immune traits
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    pmc.ncbi.nlm.nih.gov/articles/PMC13614707/
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    GLG1 in cancer-associated fibroblasts promotes bladder cancer growth while limiting tumor apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13601173/
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    Connective tissue mast cells store and release noradrenaline
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    link.springer.com/article/10.1186/s12576-023-00883-3
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    Cancers modulate processing and presentation of p53 neoantigens to evade T cell detection
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    sciencedirect.com/science/article/pii/S1074761326003481
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    Macrophages promote collagen deposition through circadian regulation of fibroblasts
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    sciencedirect.com/science/article/pii/S2589004226029524
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    TRRAP enables MMB-dependent mitotic transcription and determines sensitivity to CHK1 inhibition
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    sciencedirect.com/science/article/pii/S2211124726010636
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    Altering transcription factor binding reveals comprehensive transcriptional kinetics of a basic gene
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    pmc.ncbi.nlm.nih.gov/articles/PMC8216454/
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    Nuclear body assembly by a viral repeat RNA promotes Kaposi’s sarcoma-associated herpesvirus gene expression
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    sciencedirect.com/science/article/pii/S1097276526005915
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    Bioorthogonal Chemical Epigenetic Modifiers Enable Dose-Dependent CRISPR Targeted Gene Activation in Mammalian Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC9048219/
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    Protocol for detecting endogenous GPCR activity in primary cell cultures using ONE-GO biosensors
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    pmc.ncbi.nlm.nih.gov/articles/PMC11480228/
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    Dose-dependent activation of gene expression is achieved using CRISPR and small molecules that recruit endogenous chromatin machinery
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    pmc.ncbi.nlm.nih.gov/articles/PMC6954327/
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    Allosteric modulation of YTHDFs by ellagic acid suppresses triple-negative breast cancer via non-canonical activation of the HIF-1α pathway
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    sciencedirect.com/science/article/pii/S2666379126004623
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    Epithelial HSD11β2 as an immunometabolic checkpoint in head and neck cancer: Restoring local steroid inactivation reinvigorates T cell immunity
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    sciencedirect.com/science/article/pii/S030438352600604X
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    Chemogenomic maps reveal a PRDX1-dependent iron–damage axis in the DNA damage response
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    nature.com/articles/s41589-026-02312-z
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    Auxin-Activated Caspase 9 System (AuxiCasp9), a Suicide Switch for Engineered Cells
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    pubs.acs.org/asbcd6/article/doi/10.1021/acssynbio.6c00010/5426555/Auxin-Activated-Caspase-9-System-AuxiCasp9-a
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    SERINC2-mediated phosphatidylserine remodeling activates protrusion-localized AXL signaling to promote brain metastasis
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    sciencedirect.com/science/article/pii/S2211124726010405
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    Proteomic profiling reveals that DPP4 overexpression increases cell adhesion, inhibits cell migration, and restores androgen sensitivity in prostate cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13542909/
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    Inhibitory circuits restrain adult glioma progression by suppressing calcium-driven oncogenic programs
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    sciencedirect.com/science/article/pii/S0896627326006380
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    PARP16 is a Druggable Regulator of Ribosome MARylation and Protein Homeostasis in Ovarian Cancer Cells
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    sciencedirect.com/science/article/pii/S0021925826024129
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    Bacteroides acidifaciens enriched by KRAS mutation promotes colorectal tumorigenesis
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    Expression of tardigrade extremotolerance-associated proteins improves recovery but not acute stress response of human microvascular endothelial cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13534718/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70693
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    GATA3-extension mutants rewire lineage identity in luminal breast cancer
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    biorxiv.org/content/10.64898/2026.08.22.746471v1
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    Live-cell transcriptomics with engineered virus-like particles
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    Triple-costimulatory GD2-CAR T cells incorporating CD28, 4–1BB and CD27 mediate potent cytotoxicity and reduce exhaustion in solid tumour models
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    sciencedirect.com/science/article/pii/S0753332226009339
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    A lysis-derived PMSF and orthovanadate oxidant defines a distinct cysteine-engagement profile
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    CONCR lncRNA organizes a 3′-end structural domain that engages DDX11 for DNA replication and sister chromatid cohesion
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    sciencedirect.com/science/article/pii/S1097276526005514
  30. Aug 2026
  31. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Host metadherin coordinates hepatic lipid metabolism and CD8+ T cell immunity to promote tumor progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13623212/
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    The CNNM-binding interface drives PRL-3-dependent tumor progression in de novo cancer models
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    NUDT2 loss defines quantitative limits for dinucleoside polyphosphate action on the cGAS–STING–TBK1 axis
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    biorxiv.org/content/10.64898/2026.08.18.745545v1
  34. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ligand-independent EPHA2 signaling sustains neural progenitors via ECSIT and NAD+
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    pmc.ncbi.nlm.nih.gov/articles/PMC13503776/
  35. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inhibition of cyclin-dependent kinase 8 modulates chondrocyte transition to hypertrophy and provides in vivo protection against spontaneous osteoarthritis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13503767/
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    DDIAS shields single-stranded DNA in mitosis and promotes vertebrate brain development
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  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Circular RNA circLAMC1 Promotes Liver Regeneration by Regulating the miR‐138‐5p/Gnai2 Axis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13502427/
  38. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    LIG1 Loss in TP53-mutant Triple Negative Breast Cancer Rewires DNA Repair and Confers Sensitivity to PARP-ATR Inhibitor Combinations
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    pmc.ncbi.nlm.nih.gov/articles/PMC13482947/
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    STRA6-mediated ferroptosis and its potential association with antioxidant stress pathways in glioblastoma
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    A NEK2/ZWINT–NDC80 regulatory axis drives bladder cancer progression and chemoresistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC13490343/
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    An inflammatory bowel disease-linked lncRNA suppresses transcription factor T-BET expression in T cells to limit intestinal inflammation
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    sciencedirect.com/science/article/pii/S1074761326003183
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    Chrysosplenetin-induced TMED3 aggregation triggers unfolded protein response in pancreatic cancer
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    link.springer.com/article/10.1038/s44321-026-00506-5
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    Brain assembloids reveal efficacy and off target effects in high grade glioma brain cancer
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    Tumors exploit interclonal Hedgehog-Wnt crosstalk to drive tumor-promoting cell competition
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    sciencedirect.com/science/article/pii/S153458072600287X
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    ER-liquid condensate contacts sequester FAM134B/C and RhoA to govern cell morphology
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    sciencedirect.com/science/article/pii/S1097276526005137
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    Polyamines buffer labile iron to suppress ferroptosis
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    sciencedirect.com/science/article/pii/S009286742600872X
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    AURORA A interacts with DICER and SETD2 to promote S-phase progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458143/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    C-terminal lysine residues localise NLRP10 at lipid droplets and govern NLRP10 oligomer formation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458767/
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    The regulation of protein phosphatase 4 by FBXO42 is required for cancer cell survival
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458699/
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    Canonical and isomiR products of miR-142 enhance dendritic cell reprogramming
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    sciencedirect.com/science/article/pii/S2211124726009034
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    Spi-B and IRF1 activate tumor immunogenicity downstream of the Epstein-Barr virus protein LMP1
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    sciencedirect.com/science/article/pii/S2211124726009022
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    FOXA1 drives chemoresistance through activating Wnt pathway in small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13458387/
  53. www.science.org www.science.org
    Lipidomic profiling reveals age-dependent changes in plasma membrane lipids that affect neural stem cell aging
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    science.org/doi/10.1126/sciadv.aeh9771
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    Transcriptome-wide splicing analysis reveals HuR-regulated post-transcriptional programs in osteocytes
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    sciencedirect.com/science/article/pii/S2589004226019048
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    Latent effector T cells mediate immunotherapy responses in the bone marrow microenvironment
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    sciencedirect.com/science/article/pii/S1535610826003491
  56. advanced.onlinelibrary.wiley.com advanced.onlinelibrary.wiley.com
    Bio-Inspired Biopolymeric Implantable Platform for Localized and Sustained Drug Delivery in Solid Tumor Treatment
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    advanced.onlinelibrary.wiley.com/doi/10.1002/adfm.77242
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CRISPR activation screens identify oncogenic lncRNAs that are susceptible to CDK4/6 inhibitor treatment
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    pmc.ncbi.nlm.nih.gov/articles/PMC13287569/
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    PKR engages viral RNA and intron-retained host transcripts during poxvirus infection
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    sciencedirect.com/science/article/pii/S2211124726009162
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Timing Mechanotransduction: Mechanically Dynamic Biomaterials Reveal the Temporal Hierarchy of YAP/TAZ Control Nodes
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    pmc.ncbi.nlm.nih.gov/articles/PMC13248771/
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    Integrative 3D genome and epigenomic analysis identifies TP53RK and SYBU as critical regulators of stemness and anti-tumor immunity in HCC
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    ZNF469 drives TGF-β1/SMAD3-mediated extracellular matrix regulation in pulmonary fibrosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13394613/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Fibroblast growth factor receptor substrate 2 interactome mapping reveals novel candidate interactors associated with migration and invasion
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    pmc.ncbi.nlm.nih.gov/articles/PMC13393275/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Complement factor B deficiency promotes lung cancer progression via FOS-mediated tryptophan metabolism and immune suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13389098/
  64. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mitochondrial l-2-hydroxyglutarate is a physiological signalling metabolite
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  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392030/
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    Mevalonate pathway rewiring driven by enhancer remodelling confers resistance to KRAS inhibitors in colorectal cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392262/
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    A dual-pronged host-directed therapeutic targeting cyclophilin A and pathogenic interferon response abrogates virus-triggered pregnancy pathologies
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392008/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    COXFA4L2 upregulation preserves residual cytochrome c oxidase activity in COXFA4-related Leigh-like encephalopathy
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    pmc.ncbi.nlm.nih.gov/articles/PMC13392013/
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    Initial leukemic epigenomic state determines hypomethylating agent response
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    pmc.ncbi.nlm.nih.gov/articles/PMC13388667/
  70. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Distinct roles of MCM2-7 subunits in replication licensing in human cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13388693/
  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pink1-mediated mitophagy in the endothelium releases proteins encoded by mitochondrial DNA and activates neutrophil responses during inflammation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13423353/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    SGEF coordinates epithelial morphogenesis by regulating junction stability, collective migration, and extracellular matrix remodeling
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    pmc.ncbi.nlm.nih.gov/articles/PMC13419416/
  73. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The basal cell state maintains pancreatic cancers by controlling an immunosuppressive circuit
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404871/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The Nematicide Tioxazafen Disrupts Proteasome Function via Cytochrome P450 Bioactivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13405185/
  75. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    NNMT Loss Drives Cancer Progression by enhancing SAM availability for mTORC1 Signaling and Chromatin Methylation
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    pmc.ncbi.nlm.nih.gov/articles/PMC13430563/
  76. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PCSK9 alleviates doxorubicin-induced pyroptosis of cardiomyocytes
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  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HBx Downregulates TFEB via the CUL4A/CUL4B–DDB1 Axis to Disrupt Lysosomal Function in Hepatocellular Carcinoma Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC13406449/
  78. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Posaconazole mitigates α-amanitin-induced liver injury by inhibiting STT3B-mediated glycosylation and cellular uptake
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    pmc.ncbi.nlm.nih.gov/articles/PMC13395608/
  79. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Protocol for Measuring Drug–Target Engagement in Mouse Colorectal Cancer Organoids Using NanoBRET Assay
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    pmc.ncbi.nlm.nih.gov/articles/PMC13403122/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    EMT activates ER-to-Golgi trafficking through upregulation of REEP2 to promote lung cancer progression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13419587/
  81. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    U2AF2-regulated alternative splicing of UPP1 promotes NSCLC progression by enhancing glycolysis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13412370/
  82. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multi-omic screening identifies RBMXL3 as a primate-specific RNA-binding protein and candidate regulator of RNA metabolism in human spermatogenesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC13404310/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting TOMM40 unleashes immunogenic mitophagy to facilitate antigen presentation and immunotherapy sensitization
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    pmc.ncbi.nlm.nih.gov/articles/PMC13409098/
  84. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systems analysis reveals alternate metabolic states adopted by Mycobacterium tuberculosis across species
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    pmc.ncbi.nlm.nih.gov/articles/PMC13410760/
  85. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Strain-specific epistasis shapes fitness landscapes of APOBEC3G antagonism by HIV-1 Vif proteins
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    pmc.ncbi.nlm.nih.gov/articles/PMC13394466/
  86. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ERRγ impedes neuroendocrine prostate cancer development
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    pmc.ncbi.nlm.nih.gov/articles/PMC12863258/
  87. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Perturb-seq reveals TCF7 as a transcriptional link between MAPK- and Wnt-driven gene expression
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    pmc.ncbi.nlm.nih.gov/articles/PMC13416742/
  88. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    BET inhibition curbs macrophage inflammation, lipid accumulation, and atherogenesis by disrupting the YAP/TAZ-BRD4 axis
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