253 Matching Annotations
  1. Jun 2021
  2. www.sciencedirect.com www.sciencedirect.com
    BAP1 enhances Polycomb repression by counteracting widespread H2AK119ub1 deposition and chromatin condensation
    1
    1. scibot 30 Jun 2021
      plasmid_52962

      DOI: 10.1016/j.molcel.2021.06.020

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    sciencedirect.com/science/article/pii/S1097276521005001
  3. www.sciencedirect.com www.sciencedirect.com
    Pharmacologic modulation of RNA splicing enhances anti-tumor immunity
    1
    1. scibot 25 Jun 2021
      52962

      DOI: 10.1016/j.cell.2021.05.038

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    sciencedirect.com/science/article/pii/S0092867421006905
  4. www.sciencedirect.com www.sciencedirect.com
    The AML microenvironment catalyzes a stepwise evolution to gilteritinib resistance
    1
    1. scibot 25 Jun 2021
      Cat#52962

      DOI: 10.1016/j.ccell.2021.06.003

      Resource: RRID:Addgene_52962

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    sciencedirect.com/science/article/pii/S1535610821002865
  5. May 2021
  6. www.sciencedirect.com www.sciencedirect.com
    Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway
    1
    1. scibot 14 May 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cub.2021.04.075

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    sciencedirect.com/science/article/pii/S0960982221006229
  7. www.sciencedirect.com www.sciencedirect.com
    Surface antigen-guided CRISPR screens identify regulators of myeloid leukemia differentiation
    1
    1. scibot 09 May 2021
      Addgene_52962

      DOI: 10.1016/j.stem.2020.12.005

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    sciencedirect.com/science/article/pii/S1934590920305890
  8. www.sciencedirect.com www.sciencedirect.com
    RNF126-Mediated Reubiquitination Is Required for Proteasomal Degradation of p97-Extracted Membrane Proteins
    1
    1. scibot 07 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2020.06.023

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    sciencedirect.com/science/article/pii/S1097276520304251
  9. www.sciencedirect.com www.sciencedirect.com
    SAFB2 Enables the Processing of Suboptimal Stem-Loop Structures in Clustered Primary miRNA Transcripts
    1
    1. scibot 07 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2020.05.011

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    sciencedirect.com/science/article/pii/S1097276520303129
  10. www.sciencedirect.com www.sciencedirect.com
    A Weak Link with Actin Organizes Tight Junctions to Control Epithelial Permeability
    1
    1. scibot 05 May 2021
      Plasmid_52962

      DOI: 10.1016/j.devcel.2020.07.022

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    sciencedirect.com/science/article/pii/S1534580720305979
  11. www.sciencedirect.com www.sciencedirect.com
    Caspase cleavage releases a nuclear protein fragment that stimulates phospholipid scrambling at the plasma membrane
    1
    1. scibot 03 May 2021
      Addgene_52962

      DOI: 10.1016/j.molcel.2021.02.025

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    sciencedirect.com/science/article/pii/S1097276521001350
  12. Apr 2021
  13. www.sciencedirect.com www.sciencedirect.com
    The pyruvate-lactate axis modulates cardiac hypertrophy and heart failure
    1
    1. scibot 30 Apr 2021
      Plasmid_52962

      DOI: 10.1016/j.cmet.2020.12.003

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    sciencedirect.com/science/article/pii/S1550413120306586
  14. www.sciencedirect.com www.sciencedirect.com
    Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors
    1
    1. scibot 28 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.chom.2020.05.012

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    sciencedirect.com/science/article/pii/S1931312820302948
  15. www.sciencedirect.com www.sciencedirect.com
    Illuminating Host-Mycobacterial Interactions with Genome-wide CRISPR Knockout and CRISPRi Screens
    1
    1. scibot 27 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.cels.2020.08.010

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    sciencedirect.com/science/article/pii/S2405471220302945
  16. www.sciencedirect.com www.sciencedirect.com
    Ribosome Collisions Trigger General Stress Responses to Regulate Cell Fate
    1
    1. scibot 24 Apr 2021
      addgene_52962

      DOI: 10.1016/j.cell.2020.06.006

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    sciencedirect.com/science/article/pii/S0092867420306930
  17. www.nature.com www.nature.com
    CRL4 AMBRA1 is a master regulator of D-type cyclins
    1
    1. scibot 22 Apr 2021
      plasmid_52962

      DOI: 10.1038/s41586-021-03445-y

      Resource: RRID:Addgene_52962

      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_52962
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    nature.com/articles/s41586-021-03445-y
  18. www.sciencedirect.com www.sciencedirect.com
    Epigenomic State Transitions Characterize Tumor Progression in Mouse Lung Adenocarcinoma
    1
    1. scibot 20 Apr 2021
      Addgene_52962

      DOI: 10.1016/j.ccell.2020.06.006

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561082030310X
  19. www.sciencedirect.com www.sciencedirect.com
    Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion
    1
    1. scibot 17 Apr 2021
      plasmid_52962

      DOI: 10.1016/j.ccell.2020.04.017

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610820302166
  20. www.sciencedirect.com www.sciencedirect.com
    The dystonia gene THAP1 controls DNA double-strand break repair choice
    1
    1. scibot 15 Apr 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.molcel.2021.03.034

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S109727652100229X
  21. Mar 2021
  22. www.sciencedirect.com www.sciencedirect.com
    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
    1
    1. scibot 17 Mar 2021
      Plasmid_52962

      DOI: 10.1016/j.celrep.2021.108859

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    sciencedirect.com/science/article/pii/S221112472100173X
  23. Feb 2021
  24. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
    1
    1. scibot 28 Feb 2021
      RRID:Addgene_52962

      DOI: 10.7554/eLife.60609

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      RRID:Addgene_52962
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    elifesciences.org/articles/60609
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 Infection Depends on Cellular Heparan Sulfate and ACE2
    1
    1. scibot 26 Feb 2021
      plasmid_52962

      DOI: 10.1016/j.cell.2020.09.033

      Resource: RRID:Addgene_52962

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    ncbi.nlm.nih.gov/pmc/articles/PMC7489987/
  26. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 24 Feb 2021
      Plasmid_52962

      DOI: 10.1016/j.ccell.2019.12.002

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S1535610819305720
  27. www.cell.com www.cell.com
    TMEM41B IS A PAN-FLAVIVIRUS HOST FACTOR
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2020.12.005

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    cell.com/cell/abstract/S0092-8674(20)31627-5
  28. journals.plos.org journals.plos.org
    N-Glycans and sulfated glycosaminoglycans contribute to the action of diverse Tc toxins on mammalian cells
    1
    1. scibot 24 Feb 2021
      RRID:Addgene_52962

      DOI: 10.1371/journal.ppat.1009244

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    journals.plos.org/plospathogens/article
  29. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 23 Feb 2021
      RRID:_Addgene_52962

      DOI: 10.1016/j.ccell.2019.12.007

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_52962

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      RRIDCUR:SyntaxError RRIDCUR:Unresolved RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561081930577X
  30. www.sciencedirect.com www.sciencedirect.com
    Loss of CHD1 Promotes Heterogeneous Mechanisms of Resistance to AR-Targeted Therapy via Chromatin Dysregulation
    1
    1. scibot 11 Feb 2021
      Plasmid_52962

      DOI: 10.1016/j.ccell.2020.03.001

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561082030101X
  31. Jan 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Functional interrogation of a SARS-CoV-2 host protein interactome identifies unique and shared coronavirus host factors
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.chom.2020.12.009

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1931312820306715
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-Scale Identification of SARS-CoV-2 and Pan-coronavirus Host Factor Networks
    1
    1. scibot 29 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2020.12.006

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7796900/
  34. www.sciencedirect.com www.sciencedirect.com
    Targeted brachyury degradation disrupts a highly specific autoregulatory program controlling chordoma cell identity
    1
    1. scibot 20 Jan 2021
      Addgene_52962

      DOI: 10.1016/j.xcrm.2020.100188

      Resource: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2666379120302433
  35. www.sciencedirect.com www.sciencedirect.com
    The Tumour Suppressor TMEM127 Is a Nedd4-Family E3 Ligase Adaptor Required by Salmonella SteD to Ubiquitinate and Degrade MHC Class II Molecules
    1
    1. scibot 15 Jan 2021
      Plasmid_52962

      DOI: 10.1016/j.chom.2020.04.024

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S1931312820302511
  36. www.sciencedirect.com www.sciencedirect.com
    Functional Genomics Identify Distinct and Overlapping Genes Mediating Resistance to Different Classes of Heterobifunctional Degraders of Oncoproteins
    1
    1. scibot 07 Jan 2021
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.108532

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720315217
  37. Dec 2020
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ASH2L drives proliferation and sensitivity to bleomycin and other genotoxins in Hodgkin’s lymphoma and testicular cancer cells
    1
    1. scibot 09 Dec 2020
      RRID:Addgene_52962

      DOI: 10.1038/s41419-020-03231-0

      Resource: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7705021/
  39. www.sciencedirect.com www.sciencedirect.com
    Concurrent Mutations in STK11 and KEAP1 Promote Ferroptosis Protection and SCD1 Dependence in Lung Cancer
    1
    1. scibot 07 Dec 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.108444

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124720314339
  40. Nov 2020
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Predicting Drug Response and Synergy Using a Deep Learning Model of Human Cancer Cells
    1
    1. scibot 18 Nov 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2020.09.014

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC7737474/
  42. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    TFEB Transcriptional Responses Reveal Negative Feedback by BHLHE40 and BHLHE41
    2
    1. scibot 14 Nov 2020
      Addgene #52962

      DOI: 10.1016/j.celrep.2020.108371

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      SciCrunch record: RRID:Addgene_52962

      Curator comments: lentiCas9-Blast

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      RRID:Addgene_52962
    2. scibot 14 Nov 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108371

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      RRIDCUR:Validated RRID:Addgene_52962
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    pubmed.ncbi.nlm.nih.gov/33176151/
  43. www.sciencedirect.com www.sciencedirect.com
    G9a Promotes Breast Cancer Recurrence through Repression of a Pro-inflammatory Program
    1
    1. scibot 12 Nov 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108341

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124720313309
  44. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection
    1
    1. scibot 05 Nov 2020
      Lenti-Cas9-Blast

      DOI: 10.1016/j.cell.2020.10.028

      Resource: RRID:Addgene_52962

      Curator: @evieth

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      RRIDCUR:Missing RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S0092867420313921
  45. Oct 2020
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TMEM41B is a pan-flavivirus host factor
    1
    1. scibot 24 Oct 2020
      RRID:Addgene_52962

      DOI: 10.1101/2020.10.09.334128

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7553181/
  47. Sep 2020
  48. www.sciencedirect.com www.sciencedirect.com
    Kinetic Heterogeneity of Cancer Cell Fractional Killing
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2020.107845

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124720308263
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of BLNK and BTK as mediators of rituximab‐induced programmed cell death by CRISPR screens in GCB‐subtype diffuse large B‐cell lymphoma
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1002/1878-0261.12753

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      Curator: @evieth

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7463323/
  50. www.sciencedirect.com www.sciencedirect.com
    Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.12.007

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S153561081930577X
  51. www.sciencedirect.com www.sciencedirect.com
    MAP4K Interactome Reveals STRN4 as a Key STRIPAK Complex Component in Hippo Pathway Regulation
    1
    1. scibot 16 Sep 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.107860

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S221112472030841X
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Locally acting transcription factors regulate p53-dependent cis-regulatory element activity
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1093/nar/gkaa147

      Resource: RRID:Addgene_52962

      Curator: @evieth

      SciCrunch record: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    ncbi.nlm.nih.gov/pmc/articles/PMC7192610/
  53. www.sciencedirect.com www.sciencedirect.com
    The ARK Assay Is a Sensitive and Versatile Method for the Global Detection of DNA-Protein Crosslinks
    1
    1. scibot 05 Sep 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.celrep.2019.12.067

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124719317243
  54. www.sciencedirect.com www.sciencedirect.com
    Cell Cycle Checkpoints Cooperate to Suppress DNA- and RNA-Associated Molecular Pattern Recognition and Anti-Tumor Immune Responses
    1
    1. scibot 04 Sep 2020
      Addgene_52962

      DOI: 10.1016/j.celrep.2020.108080

      Resource: RRID:Addgene_52962

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_52962

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      RRIDCUR:Validated RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S2211124720310652
  55. Aug 2020
  56. www.sciencedirect.com www.sciencedirect.com
    Vitamin B6 Addiction in Acute Myeloid Leukemia
    1
    1. scibot 14 Aug 2020
      Addgene Plasmid #52962

      DOI: 10.1016/j.ccell.2019.12.002

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_52962

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      RRID:Addgene_52962
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    sciencedirect.com/science/article/pii/S1535610819305720
  57. Jan 2020
  58. www.nature.com www.nature.com
    α-Ketoglutarate links p53 to cell fate during tumour suppression
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1038/s41586-019-1577-5

      Resource: RRID:Addgene_52962

      Curator: @Naa003

      SciCrunch record: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    nature.com/articles/s41586-019-1577-5
  59. www.sciencedirect.com www.sciencedirect.com
    Augmenting Immunotherapy Impact by Lowering Tumor TNF Cytotoxicity Threshold
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.cell.2019.06.014

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

      SciCrunch record: RRID:Addgene_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867419306774
  60. www.sciencedirect.com www.sciencedirect.com
    Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.09.005

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819304258
  61. www.embopress.org www.embopress.org
    A genome‐wide screen identifies IRF2 as a key regulator of caspase‐4 in human cells
    1
    1. scibot 13 Jan 2020
      plasmid_52962

      DOI: 10.15252/embr.201948235

      Resource: RRID:Addgene_52962

      Curator: @Naa003

      SciCrunch record: plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    embopress.org/doi/full/10.15252/embr.201948235
  62. www.sciencedirect.com www.sciencedirect.com
    Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_52962

      DOI: 10.1016/j.ccell.2019.05.013

      Resource: RRID:Addgene_52962

      Curator: @ethanbadger

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610819302557
  63. www.sciencedirect.com www.sciencedirect.com
    Genome-wide CRISPR-Cas9 Screen Identifies Leukemia-Specific Dependence on a Pre-mRNA Metabolic Pathway Regulated by DCPS
    1
    1. scibot 13 Jan 2020
      Plasmid_52962

      DOI: 10.1016/j.ccell.2018.01.012

      Resource: RRID:Addgene_52962

      Curator: @Jmenke

      SciCrunch record: Plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1535610818300126
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Jan 2020
      plasmid_52962

      DOI: 10.1038/s41598-018-37940-6

      Resource: RRID:Addgene_52962

      Curator: @evieth

      SciCrunch record: plasmid_52962

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      RRID:Addgene_52962 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6362041/