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BAF complex-independent gene activation by SS18::SSX

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1. scibot 06 Feb 2026
  
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  DOI: 10.64898/2026.01.26.701739
  
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biorxiv.org/content/10.64898/2026.01.26.701739v1
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Male-biased Yap1-Cd276/B7-H3 axis for immune evasion in medulloblastoma

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  DOI: 10.1016/j.ccell.2026.01.005
  
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sciencedirect.com/science/article/pii/S1535610826000449
Feb 2026
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Mucin-type O-glycans regulate proteoglycan stability and chondrocyte maturation

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  DOI: 10.64898/2025.12.11.693745
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12710741/
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Multidimensional mapping of stimulation-responsive regulatory elements and candidate causal variants in T cell activation

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1. scibot 01 Feb 2026
  
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  DOI: 10.1126/sciadv.ady2539
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12757029/
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DDX6 undergoes phase separation to modulate metabolic plasticity and chemoresistance

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  DOI: 10.1038/s41467-025-66966-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12783633/
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Mapping kinase-dependent tumor immune adaptation with multiplexed single-cell CRISPR screens

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1. scibot 01 Feb 2026
  
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  plasmid_52962
  
  DOI: 10.64898/2026.01.08.698516
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12803220/
Jan 2026
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CRISPR activation screens map the genomic landscape of cancer glycome remodeling

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1. scibot 29 Jan 2026
  
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  DOI: 10.1016/j.xgen.2026.101139
  
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sciencedirect.com/science/article/pii/S2666979X26000017
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Genome-wide CRISPR screening reveals a PKA-driven resistance mechanism to metformin for oral cancer prevention that can be exploited by combination with NSAIDs

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1. scibot 28 Jan 2026
  
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  DOI: 10.1158/1940-6207.CAPR-25-0264
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12826122/
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ETV1 is a key regulator of enteroendocrine PYY production

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1. scibot 26 Jan 2026
  
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  plasmid_52962
  
  DOI: 10.1242/dmm.052610
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12746708/
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Hypoxic conditions confer chemoresistance to crizotinib but not to imatinib in chronic myeloid leukemia cells

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1. scibot 26 Jan 2026
  
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  DOI: 10.1016/j.htct.2025.106240
  
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2. scibot 13 Jan 2026
  
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  DOI: 10.1016/j.htct.2025.106240
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12818218/
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CRISPR knockout screens reveal genes and pathways essential for neuronal differentiation and implicate PEDS1 in neurodevelopment

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1. scibot 16 Jan 2026
  
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  DOI: 10.1038/s41593-025-02165-0
  
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nature.com/articles/s41593-025-02165-0
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CDK4/6 inhibition overcomes venetoclax resistance mechanisms with enhanced combination activity in acute myeloid leukemia

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1. scibot 09 Jan 2026
  
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  DOI: 10.1016/j.xcrm.2025.102526
  
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sciencedirect.com/science/article/pii/S2666379125005993
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Glioblastoma stem cells resist cuproptosis with circadian variation of copper levels

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1. scibot 06 Jan 2026
  
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  Addgene_52962
  
  DOI: 10.1172/JCI192599
  
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jci.org/articles/view/192599
Dec 2025
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The TIM22 carrier translocase supports cell proliferation by facilitating mitochondrial iron uptake for Fe-S biogenesis

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1. scibot 20 Dec 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.molcel.2025.11.022
  
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sciencedirect.com:5037/science/article/pii/S1097276525009396
54.241.53.176 54.241.53.176

misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html

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1. scibot 16 Dec 2025
  
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  DOI: 10.6084/m9.figshare.30317422
  
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54.241.53.176/7d61701eda67e5c30e5b80a91af04eaa9e6cd528/misra-et-al-2025-fam134b-controls-collagen-i-dynamics-in-hepatic-stellate-cell-driven-fibrosis-html.html
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Induced ubiquitination bypasses canonical ERAD to drive ER protein degradation

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1. scibot 06 Dec 2025
  
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  DOI: 10.1101/2025.11.28.691080
  
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biorxiv.org/content/10.1101/2025.11.28.691080v1
Nov 2025
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Harnessing the E3 ligase SPOP for targeted degradation of the NUP98::KDM5A fusion oncoprotein

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1. scibot 29 Nov 2025
  
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  plasmid_52962
  
  DOI: 10.1016/j.celrep.2025.116602
  
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sciencedirect.com:5037/science/article/pii/S2211124725013749
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ARFGAP1 serves as a critical host factor during E30 infection: QS11 inhibits viral pathogenesis in hFcRn-IFNAR−/− mice

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1. scibot 24 Nov 2025
  
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  DOI: 10.1186/s12985-025-02971-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12573814/
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Therapeutic potential of PRMT1 as a critical survival dependency target in multiple myeloma

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1. scibot 24 Nov 2025
  
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  DOI: 10.1186/s12885-025-15104-w
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12584455/
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Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia

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1. scibot 24 Nov 2025
  
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  DOI: 10.1126/sciadv.adx8662
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12525776/
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Targeting SUMOylation promotes cBAF complex stabilization and disruption of the SS18::SSX transcriptome in synovial sarcoma

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  DOI: 10.1038/s41467-025-64665-8
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12589557/
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The inner nuclear membrane protein LEMD3 organizes the 3D chromatin architecture to maintain vascular smooth muscle cell identity

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  DOI: 10.1038/s41467-025-63876-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12495022/
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SLC20A1 knockout to stably express a fusogenic gibbon ape leukemia virus envelope glycoprotein for lentiviral vector production

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1. scibot 24 Nov 2025
  
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  DOI: 10.1016/j.omtm.2025.101619
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12639841/
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Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2

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1. scibot 24 Nov 2025
  
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  plasmid_52962
  
  DOI: 10.1242/jcs.264193
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12582440/
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Directly reprogrammed NK cells driven by BCL11B depletion enhance targeted immunotherapy against pancreatic ductal adenocarcinoma

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1. scibot 24 Nov 2025
  
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  Addgene_52962
  
  DOI: 10.1186/s13045-025-01730-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12613755/
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RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia

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1. scibot 24 Nov 2025
  
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  DOI: 10.1080/15476286.2025.2580180
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12582121/
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Novel regulators of heparan sulfate proteoglycans modulate cellular uptake of α-synuclein fibrils

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1. scibot 24 Nov 2025
  
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  DOI: 10.1038/s42003-025-08786-2
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12501064/
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DeepTarget predicts anti-cancer mechanisms of action of small molecules by integrating drug and genetic screens

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  DOI: 10.1038/s41698-025-01111-4
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12589559/
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A microRNA CRISPR screen reveals microRNA-483-3p as an apoptotic regulator in prostate cancer cells

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1. scibot 24 Nov 2025
  
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  DOI: 10.1038/s41419-025-08098-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12552650/
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FRA1 (FOSL1) suppresses neoplastic transformation and modulates radiation responses via transcriptional control of mitogenic and stress-responsive networks

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1. scibot 23 Nov 2025
  
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  DOI: 10.3389/fcell.2025.1659986
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12497744/
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Up-regulating methylation of CAP1 promoter can promote apoptosis and inhibit migration and invasion of lung adenocarcinoma cells

1
1. scibot 23 Nov 2025
  
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  lentiCas9-Blast
  
  DOI: 10.1186/s40001-025-03135-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12465864/
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Loss of PTDSS1 in tumor cells improves immunogenicity and response to anti–PD-1 therapy

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  DOI: 10.1126/sciadv.adx8134
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12422196/
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Systematic discovery of CRISPR-boosted CAR T cell immunotherapies

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1. scibot 23 Nov 2025
  
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  DOI: 10.1038/s41586-025-09507-9
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12545207/
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Soluble MFGE8 mediates cell entry of Crimean-Congo hemorrhagic fever virus

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1. scibot 23 Nov 2025
  
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  Addgene_52962
  
  DOI: 10.1128/mbio.01617-25
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12505966/
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A microscopy-based CRISPR screening platform enables organellar functional genomics and illuminates ciliary biology

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1. scibot 22 Nov 2025
  
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  DOI: 10.1016/j.devcel.2025.10.015
  
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sciencedirect.com/science/article/pii/S1534580725006665
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Targeting plasticity in the pyrimidine synthesis pathway potentiates macrophage-mediated phagocytosis in pancreatic cancer models

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1. scibot 18 Nov 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1172/JCI193370
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12618067/
www.biorxiv.org www.biorxiv.org

Therapeutic Inducers of NK cell Killing (ThINKK)-induced NK cell cytotoxicity against childhood acute lymphoblastic leukemia: unraveling the dual role of TRAIL leads to the establishment of an efficacy biomarker

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1. scibot 18 Nov 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1101/2025.11.12.687655
  
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biorxiv.org/content/10.1101/2025.11.12.687655v1
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Accumulation of succinate suppresses de novo purine synthesis through succinylation-mediated control of the mitochondrial folate cycle

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Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia

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ADAR1p150 RNA binding, independent of A-to-I RNA editing, buffers immunogenicity from the tonic type I IFN induced transcriptome in vivo

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Germline-somatic liaison dictates cancer subtype via de novo steroid biosynthesis

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Tuning insulin receptor signaling using de novo-designed agonists

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1-s2.0-S2589004225019455-main-html.html

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RSK1 reprograms the ubiquitin pathway to promote immune suppression

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  AddgeneCat# 52962
  
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RBM39 degrader invigorates innate immunity to eradicate neuroblastoma despite cancer cell plasticity

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Neuropilin-2 upregulation by stromal TGFβ1 induces lung disseminated tumor cells dormancy escape and promotes metastasis outgrowth

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2025.09.04.674332v2.full-html.html

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Oxidative Phosphorylation is a Metabolic Vulnerability of Endocrine Therapy-Tolerant Persister Cells in ER+ Breast Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11908958/
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ALKBH1 drives tumorigenesis and drug resistance via tRNA decoding reprogramming and codon-biased translation

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d-cysteine impairs tumour growth by inhibiting cysteine desulfurase NFS1

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Peroxisomal lipid metabolism inhibits Pimozide-induced cancer cell death by regulating ATP homeostasis

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Therapeutic targeting of the p300/CBP bromodomain enhances the efficacy of immune checkpoint blockade therapy

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pmc.ncbi.nlm.nih.gov/articles/PMC12373458/
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An isoform-specific RUNX1C–BTG2 axis governs AML quiescence and chemoresistance.

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pmc.ncbi.nlm.nih.gov/articles/PMC12405853/
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Pooled CRISPR screens identifies key regulators of bovine stem cell expansion for cultured meat

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pmc.ncbi.nlm.nih.gov/articles/PMC12398484/
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Endogenous fine-mapping and prioritization of functional regulatory elements in complex genetic loci

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cell.com/cell-genomics/abstract/S2666-979X(25)00238-1
Aug 2025
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Perturbation of calreticulin potentiates CD8+ T cell–mediated antitumor immunity

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  DOI: 10.1084/jem.20242360
  
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rupress.org/jem/article/222/10/e20242360/278219/Perturbation-of-calreticulin-potentiates-CD8-T
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Tumor cell-adipocyte gap junctions activate lipolysis and contribute to breast tumorigenesis

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  plasmid_52962
  
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Integrated time-series analysis and high-content CRISPR screening delineate the dynamics of macrophage immune regulation

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  plasmid_52962
  
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cell.com/cell-systems/abstract/S2405-4712(25)00179-6
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The RNA-binding protein RRP1 brakes macrophage one-carbon metabolism to suppress autoinflammation

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pmc.ncbi.nlm.nih.gov/articles/PMC12297237/
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Production of SARS-CoV-2 virus-like particles as a vaccine candidate in stable cell lines through inducible E and M protein expression

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  plasmid_52962
  
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Persistent chromatin alterations and gene expression reprogramming follow widespread DNA damage in glioblastoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12262309/
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Genome-wide CRISPR/Cas9 screening identifies PTGR2 as a potential therapeutic target for sunitinib resistance in clear cell renal cell carcinoma

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Directed evolution of novel AAV variants using the MCMS library for enhanced CNS tropism and reduced liver targeting in mice

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pmc.ncbi.nlm.nih.gov/articles/PMC12272419/
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A Reflux Linked GATA Factor Fulcrum Dictates Lineage Commitment Through GPRC5B During the Esophageal Dysplastic Transition

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pmc.ncbi.nlm.nih.gov/articles/PMC12311540/
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Murine hematopoietic progenitor cell lines with erythroid and megakaryocyte potential

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Kinome reprogramming of G2/M kinases and repression of MYCN contribute to superior efficacy of lorlatinib in ALK-driven neuroblastoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12322148/
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

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  DOI: 10.1002/1878-0261.70080
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.70080
Jul 2025
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Minute amounts of helicase-deficient truncated RECQL4 are sufficient for DNA replication

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biorxiv.org/content/10.1101/2025.07.21.666025v1
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Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer

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  DOI: 10.1126/sciadv.adu0847
  
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science.org/doi/10.1126/sciadv.adu0847
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HIF-independent oxygen sensing via KDM6A regulates ferroptosis

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52.53.155.43 52.53.155.43

MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD

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DNA demethylating agents suppress preclinical models of synovial sarcoma

1
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pmc.ncbi.nlm.nih.gov/articles/PMC12208545/
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Targeting the Dependence on PIK3C3-mTORC1 Signaling in Dormancy-Prone Breast Cancer Cells Blunts Metastasis Initiation

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  DOI: 10.1158/0008-5472.CAN-23-2654
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12167933/
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HVJ-E links Apolipoprotein d to antitumor effects

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  52962
  
  DOI: 10.1136/jitc-2024-011442
  
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A rational engineering strategy for structural dynamics modulation enables target specificity enhancement of the Cas9 nuclease

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NSUN2-mediated HCV RNA m5C Methylation Facilitates Viral RNA Stability and Replication

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NINJ1 regulates plasma membrane fragility under mechanical strain

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pmc.ncbi.nlm.nih.gov/articles/PMC12210241/
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Identification of the Notch ligand DLK1 as an immunotherapeutic target and regulator of tumor cell plasticity and chemoresistance in adrenocortical carcinoma

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A Versatile Reporter Platform for Evaluating HDR- and NHEJ-Based Genome Editing in Airway Epithelial Cell Cultures Using an rAAV Vector

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Mechanism of EHMT2-mediated genomic imprinting associated with Prader-Willi syndrome

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Identification of targetable vulnerabilities of PLK1-overexpressing cancers by synthetic dosage lethality

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The AhR regulates IFN-induced immune checkpoints in lung cancer cells through HNRNPH1, an RNA-binding protein, and INCR1, a novel long non-coding RNA

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The dual‐coding gene SLC35A4 protects against oxidative stress

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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells

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Cullin-RING ligase BioE3 reveals molecular-glue-induced neosubstrates and rewiring of the endogenous Cereblon ubiquitome

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An alternate receptor for adeno-associated viruses

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High-content image-based pooled screens reveal regulators of synaptogenesis

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In vivo CRISPR activation screen identifies acyl-CoA–binding protein as a driver of bone metastasis

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Mitochondria regulate MR1 protein expression and produce self-metabolites that activate MR1-restricted T cells

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Systemic genome-epigenome analysis captures a lineage-specific super-enhancer for MYB in gastrointestinal adenocarcinoma

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Elevated nonhomologous end-joining by AATF enables efficient DNA damage repair and therapeutic resistance in glioblastoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12120020/
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Ferroptosis-activating metabolite acrolein antagonizes necroptosis and anti-cancer therapeutics

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WNK1 signalling regulates amino acid transport and mTORC1 activity to sustain acute myeloid leukaemia growth

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Copy Number Gains of VPS72 Drive De Novo Lipogenesis and Hepatocarcinogenesis via ATF3/mTORC1/SREBP1 Axis

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Evolutionary and functional analyses reveal a role for the RHIM in tuning RIPK3 activity across vertebrates

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Resistance Signatures Manifested in Early Drug Response in Cancer and Across Species

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Transcriptional and epigenetic rewiring by the NUP98::KDM5A fusion oncoprotein directly activates CDK12

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Integrative multi-omics identifies AP-1 transcription factor as a targetable mediator of acquired osimertinib resistance in non-small cell lung cancer

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Combined inhibition of KAT6A/B and Menin reverses estrogen receptor-driven gene expression programs in breast cancer

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CREPT is required for the metastasis of triple-negative breast cancer through a co-operational-chromatin loop-based gene regulation

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The genetic interaction map of the human solute carrier superfamily

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pmc.ncbi.nlm.nih.gov/articles/PMC12130552/
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APOBEC3 Activity Promotes the Survival and Evolution of Drug-Tolerant Persister Cells during EGFR Inhibitor Resistance in Lung Cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC12093302/
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A specific form of cPRC1 containing CBX4 is co-opted to mediate oncogenic gene repression in diffuse midline glioma

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Med12 cooperates with multiple differentiation signals to facilitate efficient lineage transitions in embryonic stem cells

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Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer

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Muscleblind-like proteins are novel modulators of the tumor-immune microenvironment

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  DOI: 10.1371/journal.pone.0321148
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12043120/
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Innovative evaluation of selinexor and JQ1 synergy in leukemia therapy via C-MYC inhibition

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Perturb-tracing enables high-content screening of multi-scale 3D genome regulators

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mTORC1 cooperates with tRNA wobble modification to sustain the protein synthesis machinery

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1-s2.0-S2589004225006480-main-html.html

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Targeted inhibition of PDGFRA with avapritinib, markedly enhances lenvatinib efficacy in hepatocellular carcinoma in vitro and in vivo: clinical implications

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pmc.ncbi.nlm.nih.gov/articles/PMC12057143/
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Depletion of Hepatic SREBP2 Protects Against Hypercholesterolemia and Atherosclerosis through the ANGPTL3-LPL Axis

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  lentiCas9‐Blast
  
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pmc.ncbi.nlm.nih.gov/articles/PMC12079391/
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The regulatory architecture of the primed pluripotent cell state

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pmc.ncbi.nlm.nih.gov/articles/PMC11982361/
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Loss of VHL-mediated pRb regulation promotes clear cell renal cell carcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC12003641/
Apr 2025
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Targeted demethylation of the EphA7 promoter inhibits tumorigenesis via the SP1/DNMT1 and PI3K/AKT axes and improves the response to multiple therapies in cervical cancer

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Pooled tagging and hydrophobic targeting of endogenous proteins for unbiased mapping of unfolded protein responses

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FEBS Press

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  52962; Addgene
  
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Circular RMST cooperates with lineage-driving transcription factors to govern neuroendocrine transdifferentiation

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Depletion of tumor-derived CXCL5 improves T cell infiltration and anti-PD-1 therapy response in an obese model of pancreatic cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11931939/
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Mycobacterium tuberculosis phagosome Ca2+ leakage triggers multimembrane ATG8/LC3 lipidation to restrict damage in human macrophages

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pmc.ncbi.nlm.nih.gov/articles/PMC11939036/
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Highly parallel profiling of the activities and specificities of Cas12a variants in human cells

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pmc.ncbi.nlm.nih.gov/articles/PMC11953374/
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CRISPR screens with trastuzumab emtansine in HER2-positive breast cancer cell lines reveal new insights into drug resistance

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pmc.ncbi.nlm.nih.gov/articles/PMC11959757/
Mar 2025
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CRISPR screening reveals ZNF217 as a vulnerability in high-risk B-cell acute lymphoblastic leukemia

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pmc.ncbi.nlm.nih.gov/articles/PMC11905140/
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PHGDH activation fuels glioblastoma progression and radioresistance via serine synthesis pathway

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pmc.ncbi.nlm.nih.gov/articles/PMC11921657/
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Genome-wide CRISPR screen identifies IRF1 and TFAP4 as transcriptional regulators of Galectin-9 in T cell acute lymphoblastic leukemia

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pmc.ncbi.nlm.nih.gov/articles/PMC11922064/
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Loss of JAK1 Function Causes G2/M Cell Cycle Defects Vulnerable to Kif18a Inhibition

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pmc.ncbi.nlm.nih.gov/articles/PMC11888196/
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Acute GARP Depletion Disrupts Vesicle Transport, Leading to Severe Defects in Sorting, Secretion and O‐Glycosylation

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  Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11917462/
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Lipoylation inhibition enhances radiation control of lung cancer by suppressing homologous recombination DNA damage repair

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  plasmid_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11900879/
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Onvansertib and Navitoclax Combination as a New Therapeutic Option for Mucinous Ovarian Carcinoma

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pmc.ncbi.nlm.nih.gov/articles/PMC11765470/
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Recognition of MR1-antigen complexes by TCR Vγ9Vδ2

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pmc.ncbi.nlm.nih.gov/articles/PMC11876030/
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Head and neck tumor organoid biobank for modelling individual responses to radiation therapy according to the TP53/HPV status

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pmc.ncbi.nlm.nih.gov/articles/PMC11881459/
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Nuclear stiffness through lamin A/C overexpression differentially modulates chromosomal instability biomarkers

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  Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11865694/
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Bone morphogenetic protein (BMP) signaling determines neuroblastoma cell fate and sensitivity to retinoic acid

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  Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11871043/
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1-s2.0-S2352345X25000268-main-html.html

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cmghjournal.org/article/S2352-345X(25)00026-8/fulltext
Feb 2025
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Potentiating anti-tumor immunity by re-engaging immune synapse molecules

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  RRID:Addgene_52962
  
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Combinatorial mapping of E3 ubiquitin ligases to their target substrates

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  Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11845296/
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CRISPR screen reveals modifiers of rAAV production including known rAAV infection genes playing an unexpected role in vector production

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  Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11840188/
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Repurposing NAMPT inhibitors for germinal center B-cell-like diffuse large B-cell lymphoma

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  RRID:Addgene_52962
  
  DOI: 10.1158/2643-3230.BCD-24-0020
  
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aacrjournals.org/bloodcancerdiscov/article/5/6/417/749227/Repurposing-NAMPT-Inhibitors-for-Germinal-Center-B
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MR1 gene and protein expression are enhanced by inhibition of the extracellular signal-regulated kinase ERK

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  RRID:Addgene_52962
  
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aacrjournals.org/cancerimmunolres/article/12/10/1452/748716/MR1-Gene-and-Protein-Expression-Are-Enhanced-by
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Uncoupling of Akt and mTOR signaling drives resistance to Akt inhibition in PTEN loss prostate cancers

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pmc.ncbi.nlm.nih.gov/articles/PMC11804928/
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Identification of selective SWI/SNF dependencies in enzalutamide-resistant prostate cancer

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pmc.ncbi.nlm.nih.gov/articles/PMC11794516/
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The O-glycosyltransferase C1GALT1 promotes EWSR1::FLI1 expression and is a therapeutic target for Ewing sarcoma

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  plasmid_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11788431/
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The Hippo pathway promotes platinum-based chemotherapy by inhibiting MTF1-dependent heavy metal response

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  52,962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11806854/
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SMAD4 and KRAS Status Shape Cancer Cell-Stromal Crosstalk and Therapeutic Response in Pancreatic Cancer

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  52962
  
  DOI: 10.1158/0008-5472.CAN-24-2330
  
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pmc.ncbi.nlm.nih.gov/articles/PMC7617379/
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Viral oncogene EBNALP regulates YY1 DNA binding and alters host 3D genome organization

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  DOI: 10.1038/s44319-024-00357-6
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11811279/
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MEK inhibitors lead to PDGFR pathway upregulation and sensitize tumors to RAF dimer inhibitors in NF1-deficient malignant peripheral nerve sheath tumor (MPNST)

1
1. scibot 13 Feb 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1158/1078-0432.CCR-24-1750
  
  Resource: RRID:Addgene_52962
  
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aacrjournals.org/clincancerres/article/30/22/5154/749570/MEK-Inhibitors-Lead-to-PDGFR-Pathway-Upregulation
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

7
1. scibot 07 Feb 2025
  
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  52962
  
  DOI: 10.1016/j.isci.2024.111444
  
  Resource: RRID:Addgene_52962
  
  Curator: @olekpark
  
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2. scibot 06 Feb 2025
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 05 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 04 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 03 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 02 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 01 Feb 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Tubular ER structures shaped by ER-phagy receptors engage in stress-induced Golgi bypass

1
1. scibot 07 Feb 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.devcel.2025.01.011
  
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sciencedirect.com/science/article/pii/S1534580725000310
Jan 2025
aacrjournals.org aacrjournals.org

High Expression of MHC Class I Overcomes Cancer Immunotherapy Resistance Due to IFNγ Signaling Pathway Defects

1
1. scibot 31 Jan 2025
  
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  RRID: Addgene_52962
  
  DOI: 10.1158/2326-6066.CIR-22-0815
  
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aacrjournals.org/cancerimmunolres/article/11/7/895/727496/High-Expression-of-MHC-Class-I-Overcomes-Cancer
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

31
1. scibot 31 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
3. scibot 29 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
4. scibot 28 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
5. scibot 27 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
6. scibot 26 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
7. scibot 25 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
8. scibot 24 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
9. scibot 23 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
10. scibot 22 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
11. scibot 21 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
12. scibot 20 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
13. scibot 19 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
14. scibot 18 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
15. scibot 17 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
16. scibot 16 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
17. scibot 15 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
18. scibot 14 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
19. scibot 13 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
20. scibot 12 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
21. scibot 11 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
22. scibot 10 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
23. scibot 09 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
24. scibot 08 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
25. scibot 07 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
26. scibot 06 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
27. scibot 05 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
28. scibot 04 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
29. scibot 03 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
30. scibot 02 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
31. scibot 01 Jan 2025
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/
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Targeting pancreatic cancer glutamine dependency confers vulnerability to GPX4-dependent ferroptosis

1
1. scibot 30 Jan 2025
  
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  RRID:Addgene_52962
  
  DOI: 10.1016/j.xcrm.2025.101928
  
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sciencedirect.com/science/article/pii/S2666379125000011
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

SLC35A2 gene product modulates paramyxovirus fusion events during infection

1
1. scibot 27 Jan 2025
  
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  52962
  
  DOI: 10.1371/journal.ppat.1012531
  
  Resource: RRID:Addgene_52962
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11756793/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

The Hira complex regulates Gli3R-dependent transcription in Hedgehog signaling and medulloblastoma cell growth and migration

1
1. scibot 27 Jan 2025
  
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  52962
  
  DOI: 10.1038/s41598-024-83468-3
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11697252/
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

In-depth inference of transcriptional regulatory networks reveals NPM1 as a therapeutic ribosomal regulator in MYC-amplified medulloblastoma

1
1. scibot 27 Jan 2025
  
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  plasmid_52962
  
  DOI: 10.1038/s41698-024-00792-7
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11723958/
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Targeting the mevalonate pathway potentiates NUAK1 inhibition-induced immunogenic cell death and antitumor immunity

1
1. scibot 17 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.xcrm.2024.101913
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11866496/
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The efflux pump ABCC1/MRP1 constitutively restricts PROTAC sensitivity in cancer cells

1
1. scibot 07 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1016/j.chembiol.2024.11.009
  
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sciencedirect.com/science/article/pii/S2451945624004896
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Targeting mitochondrial RNAs enhances the efficacy of the DNA-demethylating agents

1
1. scibot 04 Jan 2025
  
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  Addgene_52962
  
  DOI: 10.1038/s41598-024-80834-z
  
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nature.com/articles/s41598-024-80834-z
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Identification of modulators of the ALT pathway through a native FISH-based optical screen

1
1. scibot 03 Jan 2025
  
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  Addgene52962
  
  DOI: 10.1016/j.celrep.2024.115114
  
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sciencedirect.com/science/article/pii/S2211124724014657
Dec 2024
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Bat RNA viruses employ viral RHIMs orchestrating species-specific cell death programs linked to Z-RNA sensing and ZBP1-RIPK3 signaling

2
1. scibot 31 Dec 2024
  
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  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
  RRID:Addgene_52962
2. scibot 30 Dec 2024
  
  in Public
  
  52962
  
  Traceback (most recent call last): File "/home/ubuntu/dashboard/py/create_release_tables.py", line 54, in format_anno_for_release parsedanno = HypothesisAnnotation(anno) File "/home/ubuntu/dashboard/py/hypothesis.py", line 231, in init self.links = row['document']['link'] TypeError: string indices must be integers
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11652944/

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