1,259 Matching Annotations
  1. Nov 2023
  2. link.springer.com link.springer.com
    Multimeric immunotherapeutic complexes activating natural killer cells towards HIV-1 cure
    1
    1. scibot 10 Nov 2023
      RRID:CVCL_0045

      DOI: 10.1186/s12967-023-04669-4

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    link.springer.com/article/10.1186/s12967-023-04669-4
  3. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Wang - Druggable site near the upper vestibule determines the high affinity and P2X3-html.html
    1
    1. scibot 10 Nov 2023
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      DOI: 10.1111/bph.16273

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    52.53.155.43/11da1a56b995c87f2055b8c9b63d45233f465b04/British J Pharmacology - 2023 - Wang - Druggable site near the upper vestibule determines the high affinity and P2X3-html.html
  4. www.science.org www.science.org
    Opsonization-independent antigen-specific recognition by myeloid phagocytes expressing monoclonal antibodies
    1
    1. scibot 04 Nov 2023
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      DOI: 10.1126/sciadv.adg1812

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    science.org/doi/10.1126/sciadv.adg1812
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fasting-mimicking diet drives antitumor immunity against colorectal cancer by reducing IgA-producing cells
    1
    1. scibot 03 Nov 2023
      RRID: CVCL_0045

      DOI: 10.1158/0008-5472.CAN-23-0323

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    ncbi.nlm.nih.gov/pmc/articles/PMC10618736/
  6. www.sciencedirect.com www.sciencedirect.com
    E3 ubiquitin ligase RNF180 impairs IPO4/SOX2 complex stability and inhibits SOX2-mediated malignancy in ovarian cancer
    1
    1. scibot 03 Nov 2023
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      DOI: 10.1016/j.cellsig.2023.110961

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    sciencedirect.com/science/article/pii/S0898656823003765
  7. Oct 2023
  8. www.sciencedirect.com www.sciencedirect.com
    Methotrexate-based PROTACs as DHFR-specific chemical probes
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.chembiol.2023.09.014

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    sciencedirect.com/science/article/pii/S2451945623003331
  9. www.sciencedirect.com www.sciencedirect.com
    Lactate activates the mitochondrial electron transport chain independently of its metabolism
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.molcel.2023.09.034

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    sciencedirect.com/science/article/pii/S1097276523008006
  10. www.sciencedirect.com www.sciencedirect.com
    Interrogating direct NLRP3 engagement and functional inflammasome inhibition using cellular assays
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.chembiol.2023.09.016

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    sciencedirect.com/science/article/pii/S2451945623003355
  11. www.sciencedirect.com www.sciencedirect.com
    Proteomic profiling of centrosomes across multiple mammalian cell and tissue types by an affinity capture method
    1
    1. scibot 28 Oct 2023
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      DOI: 10.1016/j.devcel.2023.09.008

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    sciencedirect.com/science/article/pii/S1534580723004951
  12. www.sciencedirect.com www.sciencedirect.com
    The intrinsically disordered region of eIF5B stimulates IRES usage and nucleates biological granule formation
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113283

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    sciencedirect.com/science/article/pii/S2211124723012950
  13. link.springer.com link.springer.com
    Serotonin 2C receptors are also important in head-twitch responses in male mice
    1
    1. scibot 27 Oct 2023
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      DOI: 10.1007/s00213-023-06482-9

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    link.springer.com/article/10.1007/s00213-023-06482-9
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of super-specific epigenome editing by targeted allele-specific DNA methylation
    1
    1. scibot 25 Oct 2023
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    ncbi.nlm.nih.gov/pmc/articles/PMC10589950/
  15. www.science.org www.science.org
    Redox-dependent internalization of the purinergic P2Y6 receptor limits colitis progression
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1126/scisignal.abj0644

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    science.org/doi/10.1126/scisignal.abj0644
  16. www.sciencedirect.com www.sciencedirect.com
    TERRA R-loops connect and protect sister telomeres in mitosis
    1
    1. scibot 17 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113235

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    sciencedirect.com/science/article/pii/S2211124723012470
  17. 52.53.155.43 52.53.155.43
    CDK19 and CDK8 Mediator kinases drive androgen-independent in vivo growth of castration-resistant prostate cancer
    1
    1. scibot 14 Oct 2023
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      DOI: 10.1101/2023.08.08.552491

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    52.53.155.43/9964c17a6d8fec4a6a270a6588b0b357cf73bf12/2023.08.08.552491v1.full-html.html
  18. 52.53.155.43 52.53.155.43
    BPS Publications
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    1. scibot 13 Oct 2023
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      DOI: 10.1111/bph.16250

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    52.53.155.43/f37fbc64098e4c5027dd3e829756f6f062c8fd91/British J Pharmacology - 2023 - Lei - The impact of uncertainty in hERG binding mechanism on in silico predictions of-html.html
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequence-directed concentration of G protein-coupled receptors in COPII vesicles
    1
    1. scibot 07 Oct 2023
      ATCCCat# CRL-1573

      DOI: 10.1016/j.isci.2023.107969

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    ncbi.nlm.nih.gov/pmc/articles/PMC10551652/
  20. 52.53.155.43 52.53.155.43
    can-23-0323-html.html
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    1. scibot 07 Oct 2023
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    52.53.155.43/abf5c00361ae6c71690115f3542cf15680fdccaf/can-23-0323-html.html
  21. 52.53.155.43 52.53.155.43
    ccr-23-1182-html.html
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    1. scibot 07 Oct 2023
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      DOI: 10.1158/1078-0432.ccr-23-1182

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    52.53.155.43/65c36a5cdd4f77902b5a0c626487c84333ec98dd/ccr-23-1182-html.html
  22. 52.53.155.43 52.53.155.43
    mct-22-0681-html.html
    1
    1. scibot 07 Oct 2023
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      DOI: 10.1158/1535-7163.mct-22-0681

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  23. 52.53.155.43 52.53.155.43
    s41586-023-06657-6_reference-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.1038/s41586-023-06657-6

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      DOI: 10.1038/s41586-023-06657-6

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    52.53.155.43/0f3eb7b8d15ef36be47b7c18ecdf1d19ad34ca1a/s41586-023-06657-6_reference-html.html
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Carbonic Anhydrase IX/SLC1A5 Axis Regulates Glutamine Metabolism Dependent Ferroptosis in Hypoxic Tumor Cells
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1158/1535-7163.MCT-23-0041

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    ncbi.nlm.nih.gov/pmc/articles/PMC10543979/
  25. www.cell.com www.cell.com
    PUF60 promotes cell cycle and lung cancer progression by regulating alternative splicing of CDC25C
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    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113041

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    cell.com/cell-reports/abstract/S2211-1247(23)01052-5
  26. www.cell.com www.cell.com
    MMD collaborates with ACSL4 and MBOAT7 to promote polyunsaturated phosphatidylinositol remodeling and susceptibility to ferroptosis
    1
    1. scibot 06 Oct 2023
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      DOI: 10.1016/j.celrep.2023.113023

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    cell.com/cell-reports/abstract/S2211-1247(23)01034-3
  27. www.biorxiv.org www.biorxiv.org
    A gut meta-interactome map reveals modulation of human immunity by microbiome effectors
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    1. scibot 06 Oct 2023
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      DOI: 10.1101/2023.09.25.559292

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    biorxiv.org/content/10.1101/2023.09.25.559292v1
  28. 52.53.155.43 52.53.155.43
    gene-editing-of-yipf3-yipf4-calcoco1-fip200-and-at-cx6nxrde-html.html
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    1. scibot 06 Oct 2023
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      DOI: 10.17504/protocols.io.6qpvr3462vmk/v1

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    52.53.155.43/95cc157e6aa5c536f3f13f814fbac7daea93a5f6/gene-editing-of-yipf3-yipf4-calcoco1-fip200-and-at-cx6nxrde-html.html
  29. Sep 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Deubiquitinating PABPC1 by USP10 upregulates CLK2 translation to promote tumor progression in pancreatic ductal adenocarcinoma
    1
    1. scibot 29 Sep 2023
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      DOI: 10.1016/j.canlet.2023.216411

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    sciencedirect.com/science/article/abs/pii/S0304383523003622
  31. 52.53.155.43 52.53.155.43
    can-23-0323-html.html
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    1. scibot 22 Sep 2023
      RRID:  CVCL_0045

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    52.53.155.43/abf5c00361ae6c71690115f3542cf15680fdccaf/can-23-0323-html.html
  32. www.nature.com www.nature.com
    Structure-guided AAV capsid evolution strategies for enhanced CNS gene delivery
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    1. scibot 22 Sep 2023
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    nature.com/articles/s41596-023-00875-y
  33. www.sciencedirect.com www.sciencedirect.com
    miR-770-5p regulates EMT and invasion in TNBC cells by targeting DNMT3A
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    1. scibot 19 Sep 2023
      RRID:CVCL_0045

      DOI: 10.1016/j.cellsig.2021.109996

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    sciencedirect.com/science/article/pii/S089865682100084X
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Divergent regulation of KCNQ1/E1 by targeted recruitment of protein kinase A to distinct sites on the channel complex
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      DOI: 10.7554/eLife.83466

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    ncbi.nlm.nih.gov/pmc/articles/PMC10499372/
  35. 52.53.155.43 52.53.155.43
    The FEBS Journal - 2023 - Takeuchi-html.html
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    52.53.155.43/1a52c544b293ec29827fcbda62621cbc0bb29fbf/The FEBS Journal - 2023 - Takeuchi-html.html
  36. journals.physiology.org journals.physiology.org
    Pore residues of transient receptor potential channels canonical 1 and 4 heteromer determine channel properties
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      DOI: 10.1152/ajpcell.00488.2022

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    journals.physiology.org/doi/10.1152/ajpcell.00488.2022
  37. www.sciencedirect.com www.sciencedirect.com
    A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants
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    sciencedirect.com/science/article/pii/S2211124723011154
  38. link.springer.com link.springer.com
    The ubiquitin specific protease 7 stabilizes HPV16E7 to promote HPV-mediated carcinogenesis
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      DOI: 10.1007/s00018-023-04941-2

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    link.springer.com/article/10.1007/s00018-023-04941-2
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RLY-4008, the first highly selective FGFR2 inhibitor with activity across FGFR2 alterations and resistance mutations
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      RRID:CVCL_0045

      DOI: 10.1158/2159-8290.CD-23-0475

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    ncbi.nlm.nih.gov/pmc/articles/PMC10481131/
  40. 52.53.155.43 52.53.155.43
    British J Pharmacology - 2023 - Kleszcz-html.html
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    1. scibot 07 Sep 2023
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      DOI: 10.1111/bph.16224

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    52.53.155.43/bda5ca2ff5fc6352261b5aa6b5327e2f6367b095/British J Pharmacology - 2023 - Kleszcz-html.html
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery and Preclinical Characterization of XMT-1660, an Optimized B7-H4-Targeted Antibody-Drug Conjugate for the Treatment of Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10477829/
  42. 52.53.155.43 52.53.155.43
    The FEBS Journal - 2023 - Christie-html.html
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      DOI: 10.1111/febs.16948

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  43. 52.53.155.43 52.53.155.43
    Distinctive Interactomes of RNA polymerase II phosphorylation during different stages of transcription
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  44. Aug 2023
  45. elifesciences.org elifesciences.org
    The Axin scaffold protects the kinase GSK3β from cross-pathway inhibition
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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long-term safety and dose escalation of intracerebroventricular CLN5 gene therapy in sheep supports clinical translation for CLN5 Batten disease
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activator protein-1 (AP-1) signaling inhibits the growth of Ewing sarcoma cells in response to DNA replication stress
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  48. link.springer.com link.springer.com
    Regulation of rat HspB5/alphaB-Crystallin by microRNAs miR-101a-3p, miR-140-5p, miR-330-5p, and miR-376b-3p
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    Recognition determinants of improved HIV-1 neutralization by a heavy chain matured pediatric antibody
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  50. www.science.org www.science.org
    A succinate/SUCNR1-brush cell defense program in the tracheal epithelium
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  51. 52.53.155.43 52.53.155.43
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  52. 52.53.155.43 52.53.155.43
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  53. www.sciencedirect.com www.sciencedirect.com
    S-acylation of the Wnt receptor Frizzled-5 by zDHHC5 controls its cellular localization and synaptogenic activity in the rodent hippocampus
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inducible nonhuman primate models of retinal degeneration for testing end-stage therapies
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A succinate/SUCNR1-brush cell defense program in the tracheal epithelium
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differentiation block in acute myeloid leukemia regulated by intronic sequences of FTO
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  57. link.springer.com link.springer.com
    Exploring the therapeutic potential of an antinociceptive and anti-inflammatory peptide from wasp venom
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  58. Jul 2023
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improved approaches to channel capacity estimation discover compromised GPCR signaling in diverse cancer cells
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Construction of the systemic anticancer immune environment in tumour-bearing humanized mouse by using liposome-encapsulated anti-programmed death ligand 1 antibody-conjugated progesterone
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    Phosphorylated S6K1 and 4E-BP1 play different roles in constitutively active Rheb-mediated retinal ganglion cell survival and axon regeneration after optic nerve injury
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis of copy number variation-associated lncRNAs identifies candidates contributing to the etiologies of congenital kidney anomalies
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  63. www.sciencedirect.com www.sciencedirect.com
    Chemogenetic regulation of the TARP-lipid interaction mimics LTP and reversibly modifies behavior
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  64. 52.53.155.43 52.53.155.43
    Combinatorial Regimens Augment Drug Monotherapy for SARS-CoV-2 Clearance in Mice
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combinatorial selective ER-phagy remodels the ER during neurogenesis
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    British J Pharmacology - 2023 - Daniluk - pH‐dependent modulation of TRPV1 by modality‐selective antagonists-html.html
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  67. www.sciencedirect.com www.sciencedirect.com
    Activation of autophagy depends on Atg1/Ulk1-mediated phosphorylation and inhibition of the Hsp90 chaperone machinery
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    Inositol polyphosphate multikinase modulates redox signaling through nuclear factor erythroid 2-related factor 2 and glutathione metabolism
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  69. 52.53.155.43 52.53.155.43
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  70. pubs.acs.org pubs.acs.org
    Aptamer Reduces Aggregation of Mutant Huntingtin and Rescues Proteostasis Network in Non-Neuronal and Neuronal Cells
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  71. www.nature.com www.nature.com
    E3 ligase MG53 suppresses tumor growth by degrading cyclin D1
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  72. www.sciencedirect.com www.sciencedirect.com
    Biological response and cell death signaling pathways modulated by tetrahydroisoquinoline-based aldoximes in human cells
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  73. 52.53.155.43 52.53.155.43
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    TMEM106B is a receptor mediating ACE2-independent SARS-CoV-2 cell entry
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    The kinesin Kif21b regulates radial migration of cortical projection neurons through a non-canonical function on actin cytoskeleton
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    Metabolic regulation of CTCF expression and chromatin association dictates starvation response in mice and flies
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  77. Jun 2023
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    Ccdc85c-Par3 condensates couple cell polarity with Notch to control neural progenitor proliferation
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    Peptide-mediated inhibition of the transcriptional regulator Elongin BC induces apoptosis in cancer cells
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  80. rupress.org rupress.org
    Membrane shapers from two distinct superfamilies cooperate in the development of neuronal morphology
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  81. www.nature.com www.nature.com
    Neural crest-related NXPH1/α-NRXN signaling opposes neuroblastoma malignancy by inhibiting organotropic metastasis
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Lipoprotein(a) induces caspase-1 activation and IL-1 signaling in human macrophages
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  83. www.nature.com www.nature.com
    Signaling-specific inhibition of the CB1 receptor for cannabis use disorder: phase 1 and phase 2a randomized trials
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  84. www.biorxiv.org www.biorxiv.org
    DNA-guided transcription factor cooperativity shapes face and limb mesenchyme
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    A furin-deficient HEK293 cell line suggests a role for furin trafficking in the intoxication pathway of recombinant immunotoxins based on Pseudomonas exotoxin A
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    The UBX domain in UBXD1 organizes ubiquitin binding at the C-terminus of the VCP/p97 AAA-ATPase
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  87. www.embopress.org www.embopress.org
    STAT1 is required to establish but not maintain interferon-γ-induced transcriptional memory
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  88. www.sciencedirect.com www.sciencedirect.com
    Secreted ORF8 induces monocytic pro-inflammatory cytokines through NLRP3 pathways in severe patients with COVID-19
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    The E3 ubiquitin ligase FBXL6 controls the quality of newly synthesized mitochondrial ribosomal proteins
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  90. www.science.org www.science.org
    A prolyl oligopeptidase inhibitor reduces tau pathology in cellular models and in mice with tauopathy
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  91. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    Targeting formyl peptide receptor 1 by anteiso-C13-surfactin for neutrophil-dominant acute respiratory distress syndrome
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    52.53.155.43/1687060009c035eea75940e2b9808e7b90a23cc3/British J Pharmacology - 2023 - Glenn - RAMP and MRAP Accessory Proteins have Selective Effects on Expression and-html.html
  94. www.biorxiv.org www.biorxiv.org
    Cation permeability and pore dynamics in TRPV1 ion channels
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    Rare heterozygous loss-of-function variants in the human GLP-1 receptor do not associate with cardiometabolic phenotypes
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  96. May 2023
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modulation of G-protein activation, calcium currents and opioid receptor phosphorylation by the pH-dependent antinociceptive agonist NFEPP
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    52.53.155.43/c9fab8af2000c3f3275be34bf7db13e9349dd36b/British J Pharmacology - 2023 - Mortensen - Pregnenolone sulphate analogues differentially modulate GABAA receptor closed-html.html
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    PhosY-secretome profiling combined with kinase-substrate interaction screening defines active c-Src-driven extracellular signaling
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    Golgi-IP, a tool for multimodal analysis of Golgi molecular content
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  101. www.nature.com www.nature.com
    Molecular-electromechanical system for unamplified detection of trace analytes in biofluids
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  102. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Activation of Wnt/β‐catenin signaling restores insulin sensitivity in insulin resistant neurons through transcriptional regulation of IRS‐1
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    The carboxyl-terminal sequence of PUMA binds to both anti-apoptotic proteins and membranes
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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Treatment of Prostate Cancer with CD46-targeted 225Ac Alpha Particle Radioimmunotherapy
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    MicroRNA-31 induced by Fusobacterium nucleatum infection promotes colorectal cancer tumorigenesis
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    Glutamate-releasing BEST1 channel is a new target for neuroprotection against ischemic stroke with wide time window
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    Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells
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    Enhanced functional detection of synaptic calcium-permeable AMPA receptors using intracellular NASPM
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    The T1150A cancer mutant of the protein lysine dimethyltransferase NSD2 can introduce H3K36 trimethylation
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    In Situ Tumor Vaccine Expressing Anti-CD47 Antibody Enhances Antitumor Immunity
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    HOXB3 drives WNT-activation associated progression in castration-resistant prostate cancer
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    The ribosome-associated protein RACK1 represses Kir4.1 translation in astrocytes and influences neuronal activity
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  115. www.thelancet.com www.thelancet.com
    Humoral and cellular response induced by a second booster of an inactivated SARS-CoV-2 vaccine in adults
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    Bilirubin gates the TRPM2 channel as a direct agonist to exacerbate ischemic brain damage
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    Intermittent hypoxia-induced enhancement of sociability and working memory associates with CNTNAP2 upregulation
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    Targeting thiol isomerase activity with zafirlukast to treat ovarian cancer from the bench to clinic
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  120. www.nature.com www.nature.com
    Astrocyte–neuron subproteomes and obsessive–compulsive disorder mechanisms
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    Cell-to-cell variability in Myc dynamics drives transcriptional heterogeneity in cancer cells
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    The circ_0002538/miR-138-5p/plasmolipin axis regulates Schwann cell migration and myelination in diabetic peripheral neuropathy
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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    UBQLN2 restrains the domesticated retrotransposon PEG10 to maintain neuronal health in ALS
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  125. www.nature.com www.nature.com
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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MANP (M-Atrial Natriuretic Peptide) Reduces Blood Pressure and Furosemide-Induced Increase in Aldosterone in Hypertension
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The length of FOXE1 polyalanine tract in congenital hypothyroidism: Evidence for a pathogenic role from familial, molecular and cohort studies
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    Malonylation of Acetyl-CoA carboxylase 1 promotes hepatic steatosis and is attenuated by ketogenic diet in NAFLD
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  129. Mar 2023
  130. www.sciencedirect.com www.sciencedirect.com
    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
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    m6A-driven SF3B1 translation control steers splicing to direct genome integrity and leukemogenesis
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    Design and development of novel, short, stable dynorphin-based opioid agonists for safer analgesic therapy
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microstructured soft devices for the growth and analysis of populations of homogenous multicellular tumor spheroids
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  134. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Codon adaptation by synonymous mutations impacts the functional properties of the estrogen receptor-alpha protein in breast cancer cells
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    Redox proteomics combined with proximity labeling enables monitoring of localized cysteine oxidation in cells
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    Transcriptional Regulation of Liver-Type OATP1B3 (Lt-OATP1B3) and Cancer-Type OATP1B3 (Ct-OATP1B3) Studied in Hepatocyte-Derived and Colon Cancer-Derived Cell Lines
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  138. Feb 2023
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Phase separation of an actin nucleator by junctional microtubules regulates epithelial function
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    A bat MERS-like coronavirus circulates in pangolins and utilizes human DPP4 and host proteases for cell entry
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  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation-pathway transitions in human voltage-gated proton channels revealed by a non-canonical fluorescent amino acid
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  142. journals.physiology.org journals.physiology.org
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  143. journals.physiology.org journals.physiology.org
    Loss-of-function KCa2.2 mutations abolish channel activity
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  144. journals.physiology.org journals.physiology.org
    Nav1.7-P610T mutation in 2 siblings with persistent ocular pain after corneal axon transection: impaired slow-inactivation and hyperexcitable trigeminal neurons
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    KDM5A Inhibits Antitumor Immune Responses Through Downregulation of the Antigen-Presentation Pathway in Ovarian Cancer
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    Single nucleus multiomics identifies ZEB1 and MAFB as candidate regulators of Alzheimer’s disease-specific cis-regulatory elements
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    Comprehensive characteristics of pathological subtypes in testicular germ cell tumor: Gene expression, mutation and alternative splicing
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  148. Jan 2023
  149. www.sciencedirect.com www.sciencedirect.com
    Loss of RanGAP1 drives chromosome instability and rapid tumorigenesis of osteosarcoma
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    Neurotransmitter release progressively desynchronizes in induced human neurons during synapse maturation and aging
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    Primary cilia are WNT-transducing organelles whose biogenesis is controlled by a WNT-PP1 axis
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    CNTNAP2 Protein Is Degraded by the Ubiquitin–Proteasome System and the Macroautophagy-Lysosome Pathway
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    The regulatory role of the CD2AP/TKS4 interaction in EMT and its potential as a biomarker for colon cancer
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    A TREM2-activating antibody with a blood–brain barrier transport vehicle enhances microglial metabolism in Alzheimer’s disease models
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    Inactive disease in patients with lupus is linked to autoantibodies to type I interferons that normalize blood IFNα and B cell subsets
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    Mechanotransduction by Membrane Proteins: TMEM120A/TACAN inhibits mechanically activated PIEZO2 channels
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  157. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    ANALYSIS OF A PANEL OF TMEM16A CHLORIDE CHANNEL INHIBITORS REVEALS INDIRECT MECHANISMS INVOLVING ALTERATION OF CALCIUM SIGNALING
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    DIAPH3 condensates formed by liquid-liquid phase separation act as a regulatory hub for stress-induced actin cytoskeleton remodeling
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    Differential effects of mutations of POPDC proteins on heteromeric interaction and membrane trafficking
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    Genetic ablation of diabetes-associated gene Ccdc92 reduces obesity and insulin resistance in mice
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Fc-effector function of COVID-19 convalescent plasma contributes to SARS-CoV-2 treatment efficacy in mice
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    The human CNOT1-CNOT10-CNOT11 complex forms a structural platform for protein-protein interactions
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  164. Dec 2022
  165. www.sciencedirect.com www.sciencedirect.com
    Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia
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    Magnetic resonance imaging focused on the ferritin heavy... : Neural Regeneration Research
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    Phellinus baumii Polyphenol: A Potential Therapeutic Candidate against Lung Cancer Cells
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  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genetically engineered, stem-cell-derived cellular vaccine
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRCA1 mediates protein homeostasis through the ubiquitination of PERK and IRE1
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    USP32-regulated LAMTOR1 ubiquitination impacts mTORC1 activation and autophagy induction
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen-regulated MafB drives cell migration via MMP11-dependent extracellular matrix remodeling in mice
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  172. aacrjournals.org aacrjournals.org
    Exploiting ligand binding domain dimerization for development of novel androgen receptor inhibitors
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Separating the contributions of SLC26A9 and CFTR to anion secretion in primary human bronchial epithelia
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      DOI: 10.1152/ajplung.00563.2020

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  174. Nov 2022
  175. www.science.org www.science.org
    Intronic enhancers of the human SNCA gene predominantly regulate its expression in brain in vivo
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      DOI: 10.1126/sciadv.abq6324

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  176. www.sciencedirect.com www.sciencedirect.com
    Systemic administration of novel engineered AAV capsids facilitates enhanced transgene expression in the macaque CNS
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  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Downregulation of protein kinase C gamma reduces epithelial property and enhances malignant phenotypes in colorectal cancer cells
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
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  179. www.sciencedirect.com www.sciencedirect.com
    Long non-coding RNA PCAT19 safeguards DNA in quiescent endothelial cells by preventing uncontrolled phosphorylation of RPA2
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  180. www.nature.com www.nature.com
    R1441C and G2019S LRRK2 knockin mice have distinct striatal molecular, physiological, and behavioral alterations
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  181. www.sciencedirect.com www.sciencedirect.com
    Molecular recognition of morphine and fentanyl by the human μ-opioid receptor
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  182. www.sciencedirect.com www.sciencedirect.com
    Monitoring fusion kinetics of viral and target cell membranes in living cells using a SARS-CoV-2 spike protein-mediated membrane fusion assay
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  183. www.sciencedirect.com www.sciencedirect.com
    Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasma membrane protrusions mediate host cell–cell fusion induced by Burkholderia thailandensis
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  185. www.sciencedirect.com www.sciencedirect.com
    Soluble T-cadherin promotes pancreatic β-cell proliferation by upregulating Notch signaling
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    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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  187. www.sciencedirect.com www.sciencedirect.com
    FOXA2 drives lineage plasticity and KIT pathway activation in neuroendocrine prostate cancer
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      CRL-1573

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  188. www.sciencedirect.com www.sciencedirect.com
    Nuclear stabilization of p53 requires a functional nucleolar surveillance pathway
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      CRL-1573

      DOI: 10.1016/j.celrep.2022.111571

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  189. www.sciencedirect.com www.sciencedirect.com
    Multi-omic profiling reveals the ataxia protein sacsin is required for integrin trafficking and synaptic organization
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      CRL1573

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  190. www.sciencedirect.com www.sciencedirect.com
    Targeted degradation of PCNA outperforms stoichiometric inhibition to result in programed cell death
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  191. Oct 2022
  192. www.nature.com www.nature.com
    HT-smFISH: a cost-effective and flexible workflow for high-throughput single-molecule RNA imaging
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      RRID: CVCL_0045

      DOI: 10.1038/s41596-022-00750-2

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  193. www.sciencedirect.com www.sciencedirect.com
    Hotspot mutations in the structured ENL YEATS domain link aberrant transcriptional condensates and cancer
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      CRL-1573

      DOI: 10.1016/j.molcel.2022.09.034

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  194. www.sciencedirect.com www.sciencedirect.com
    Alternative cleavage and polyadenylation generates downstream uncapped RNA isoforms with translation potential
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      CRL-1573

      DOI: 10.1016/j.molcel.2022.09.036

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  195. www.sciencedirect.com www.sciencedirect.com
    An unusual mode of baseline translation adjusts cellular protein synthesis capacity to metabolic needs
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      RRID:CVCL_0045

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SERINC proteins potentiate antiviral type I IFN production and proinflammatory signaling pathways
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      RRID:CVCL_0045

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  197. www.nature.com www.nature.com
    A proteome-scale map of the SARS-CoV-2–human contactome
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      DOI: 10.1038/s41587-022-01475-z

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  198. www.sciencedirect.com www.sciencedirect.com
    Calcineurin dephosphorylates topoisomerase IIβ and regulates the formation of neuronal-activity-induced DNA breaks
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  199. Sep 2022
  200. insight.jci.org insight.jci.org
    HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1<b>α</b>/ERR<b>α</b> axis
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      RRID:CVCL_0045

      DOI: 10.1172/jci.insight.159600

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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Methanol extraction revealed anticancer compounds Quinic Acid, 2(5H)‑Furanone and Phytol in Andrographis paniculata
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    Nanoscopic dopamine transporter distribution and conformation are inversely regulated by excitatory drive and D2 autoreceptor activity
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      HEK cells

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    A new monoclonal antibody enables BAR analysis of subcellular importin β1 interactomes
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of 100 LRRK2 variants linked to Parkinson's disease on kinase activity and microtubule binding
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      RRID:CVCL_0045

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    Endothelial cells regulated by RNF20 orchestrate the proliferation and differentiation of neural precursor cells during embryonic development
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    Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer
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      Human: HEK-293T

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    Increased glucose metabolism in TAMs fuels O-GlcNAcylation of lysosomal Cathepsin B to promote cancer metastasis and chemoresistance
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      HEK293T

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    Genetic- and diet-induced ω-3 fatty acid enrichment enhances TRPV4-mediated vasodilation in mice
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      CRL-1573

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    Dopamine drives neuronal excitability via KCNQ channel phosphorylation for reward behavior
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    Functional rewiring of G protein-coupled receptor signaling in human labor
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    The human mitochondrial genome contains a second light strand promoter
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      CVCL_0045

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    Discovery and intranasal administration of a SARS-CoV-2 broadly acting neutralizing antibody with activity against multiple Omicron subvariants
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  213. Aug 2022
  214. www.sciencedirect.com www.sciencedirect.com
    A TCF7L2-responsive suppression of both homeostatic and compensatory remyelination in Huntington disease mice
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      ATCCCRL-1573

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