1,712 Matching Annotations
  1. Dec 2025
  2. 54.241.53.176 54.241.53.176
    2025.12.16.694090v1.full-html.html
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    Mitochondrial VHL rewires cell metabolism in hypoxia
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    sciencedirect.com:5037/science/article/pii/S1550413125005273
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    CD8+ T cell antitumor immunity via human iNKT-DC conjugates
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    pmc.ncbi.nlm.nih.gov/articles/PMC12716482/
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70358
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    KRT81 promotes metastasis of colorectal cancer by acting as a protein scaffold for ezrin
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    nature.com/articles/s41388-025-03665-w
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    γ-Secretase exosites as targets for substrate-selective lowering of Aβ generation
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    sciencedirect.com:5037/science/article/pii/S0969212625004447
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    miRNA modules for precise, tunable control of gene expression
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    sciencedirect.com:5037/science/article/pii/S1097276525009694
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    RAS mutation–specific responses to paralog- and state-selective RAS inhibitors
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    Liprin-α1 enhances PHLDB3 oncogenic function in colorectal cancer via activation of mTORC2-AKT1 pathway
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    sciencedirect.com:5037/science/article/pii/S2211124725014949
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    Rational engineering of an antifreeze-based biomaterial with dual-enhanced ice-binding and delivery for high-efficiency cryopreservation
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    sciencedirect.com:5037/science/article/pii/S2090123225009981
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    Cell line engineering for enhanced measles virus production with sphingosine kinase 1 gene overexpression
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    link.springer.com/article/10.1007/s11262-025-02206-7
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    Domain associated with zinc fingers-containing NF90-NF45 complex inhibits m6A modification of primary microRNA by suppressing METTL3/14 activity
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    febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.70173
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    Involvement of a tick-borne orthomyxovirus matrix protein in vRNP nuclear export
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    journals.asm.org/doi/10.1128/jvi.01494-25
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    Comprehensive characterization and targeted treatment of a pediatric epithelioid glioblastoma with a rare TRIM24-NTRK2 fusion
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    nature.com/articles/s41698-025-01190-3
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    Loss of UXS1 Selectively Depletes Pyrimidines and Induces Replication Stress in KEAP1-Mutant Lung Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12666321/
  17. Nov 2025
  18. 54.241.53.176 54.241.53.176
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    Structural basis for binding of RILPL1 to TMEM55B reveals a lysosomal platform for adaptor assembly through a conserved peptide motif
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    Menin-MLL1 complex cooperates with NF-Y to promote hepatocellular carcinoma survival
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    Identification of antimalarial drugs and bradykinin as ligands of the Plasmodium membrane protein PfSR10
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    pmc.ncbi.nlm.nih.gov/articles/PMC12639566/
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    Multilevel characterization of genome editor nuclease activity with BreakTag
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    Elucidating pathway-selective biased CCKBR agonism for Alzheimer’s disease treatment
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    The crystal structure of the activin B:Fst288 complex and computational insights into the broad antagonistic activity and specificity of follistatin
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    HSP90 buffers deleterious genetic variations in BRCA1
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    Cytoplasmic calcium influx mediated by Lr14a regulates stomatal immunity against leaf rust in wheat
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    Non-orthosteric inhibition of enolase 1 impedes growth of triple-negative breast cancer
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    Sparse delivery of Synaptobrevin-2 to neurons using extracellular vesicles
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    Nuclear-lamin-guided plastic positioning and folding of the human genome
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    Identification of ATG7 as a protein ATG8ylation substrate
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    IGF2BP2 promotes malignant progression of ovarian cancer by regulating protein synthesis through liquid-liquid phase separation
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  36. Oct 2025
  37. www.biorxiv.org www.biorxiv.org
    L-asparaginase treatment induces a tumor metabolic plasticity and reveals a vulnerability to PARP1/2 inhibitor Olaparib, in B-cell lymphomas
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    biorxiv.org/content/10.1101/2025.10.24.683536v1
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    Plakophilin 3 drives acinar cell transformation and promotes cancer initiation and progression in pancreas
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    Unveiling conformation-selective regulation of the norepinephrine transporter
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  40. www.biorxiv.org www.biorxiv.org
    Omega-3 Fatty Acid Derived Neuroactive Lipids - Docosahexaenoyl-Glycine and Its Epoxide Metabolites are Multifunctional Lipid Mediators
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    biorxiv.org/content/10.1101/2025.10.17.681057v1
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    Balancing Activation and Repression: CoREST-p300 Antagonism Controls Retinoic Acid-Driven Differentiation in AML
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    PEX14 acts as a molecular link between optineurin and the autophagic machinery to induce pexophagy
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    rupress.org/jcb/article/224/11/e202411184/278363/PEX14-acts-as-a-molecular-link-between-optineurin
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    Inducible CRISPR–Cas9 screening platform to interrogate non-proliferative cellular states
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  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Long noncoding RNA-dependent control of Myc transcriptional bursting
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    Small-molecule OPA1 inhibitors reverse mitochondrial adaptations to overcome therapy resistance in acute myeloid leukemia
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    Enhancing cap-independent translation of linear mRNA
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    Caloric Restriction Enhances the Efficacy of Anti-Androgen Therapy in Prostate Cancer by Inhibiting Androgen Receptor Translation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12535181/
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    Characterization of ITIH6, a novel inter-α-inhibitor family member with prognostic significance in cholangiocarcinoma
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    sciencedirect.com/science/article/pii/S0141813025089172
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    Magnetic nanomotor-enhanced DNA cascade reaction for imaging DNA repair-related enzyme activity
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    Mammalian TatD DNase domain containing 1 (TATDN1) is a proteostasis‐responsive gene with roles in ventricular structure and neuromuscular function
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    A novel Frizzled 7 antibody disrupts the Wnt pathway and inhibits Wilms tumor growth
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    Redox‐dependent binding and conformational equilibria govern the fluorescence decay of NAD(P)H in living cells
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    Phosphorylation of Plectin by Akt3 Promotes Triple-Negative Breast Cancer Cell Invasive Migration
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    Machine-learning-guided discovery of SLC25A45 as a mediator of mitochondrial methylated amino acid import and carnitine synthesis
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    A nanobody-based tri-specific NK cell engager targeting CD5 triggers antitumor immunity
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    Selective targeting of coagulation factor X Gla domain by negatively charged gold nanoparticles: a novel method for controlled antithrombotic therapy
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    pORF3-driven biogenesis of lipid droplets facilitates HEV infectivity
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    Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements
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    In situ extended immune activation instantly after tumor resection by oncolytic virus controls postoperative tumor recurrence
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  60. pubs.acs.org pubs.acs.org
    Development of a Cell Membrane Conformational Cannabinoid CB1 Receptor Biosensor for the Detection of Synthetic Cannabinoids
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  61. www.biorxiv.org www.biorxiv.org
    DGAT1 as a Racially Divergent Driver of Carcinoma-Associated Fibroblast Activation Drives Tumorigenic Pathways via ERK1/2 Signaling in Prostate Cancer
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    Antineoplastic Activity of a Novel Trispecific Single-Chain Antibody Targeting the hERG1/β1 Integrin Complex and TRAIL Receptors
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    Carbonic Anhydrase Inhibition Sensitizes Group 3 Medulloblastoma to Radiation Therapy
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    Valence and avidity determine the agonistic activity of anti-TNFR2 nanobody fusion proteins
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  65. Sep 2025
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cryo-EM snapshots of NMDA receptor activation illuminate sequential rearrangements
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    Store-independent activation of STIM1-ORAI1 by SPCA2 determines the basal CFTR activity in secretory epithelial cells
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    Reduced oxytocin signaling in the dBNST drives the transition from acute pain to persistent anxiety
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    A Bacteroides fragilis protease activates host PAR2 to induce intestinal pain and inflammation
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    Post-transcriptional control of KRAS: functional roles of 5′UTR RNA G-quadruplexes, long noncoding RNA, and hnRNPA1
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    PPM1D is directly degraded by proteasomes in a ubiquitination-independent manner through its carboxyl-terminal region
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    Spatial and longitudinal tracking of enhancer-AAV vectors that target transgene expression to injured mouse myocardium
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    Drug–Drug Interaction Liabilities with BTK Inhibitor TL-895
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    Heart failure-specific cardiac fibroblasts contribute to cardiac dysfunction via the MYC–CXCL1–CXCR2 axis
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    Sympathetic Neurons Promote Small Cell Lung Cancer Through the Beta-2 Adrenergic Receptor
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    Preclinical Evaluation of PTK7-Targeted Radionuclide Therapy
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    DNA-encoded library screening uncovers potent DNMT2 inhibitors targeting a cryptic allosteric binding site
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    Cross-species analysis identifies genotype-driven vulnerabilities in lung adenocarcinoma
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    Aberrant coupling of glutamate and tyrosine kinase receptors enables neuronal control of brain-tumor growth
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    SLC6A8-mediated creatine uptake suppresses ERK2-FSP1 signaling and induces ferroptosis in colorectal cancer
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    Stereoselectivity and functional plasticity of a common ligand-binding pocket in TRPM3
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    biorxiv.org/content/10.1101/2025.08.27.671268v1
  85. Aug 2025
  86. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    A novel peptide-fentanyl conjugate with μ-opioid and neuropeptide FF receptor agonism produces antinociception with limited side effects in male mice
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.70178
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    Proximity-specific ribosome profiling reveals the logic of localized mitochondrial translation
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  88. rupress.org rupress.org
    Identification of organelle-specific autophagy regulators from tandem CRISPR screens
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    rupress.org/jcb/article/224/10/e202405138/278221/Identification-of-organelle-specific-autophagy
  89. 52.53.155.43 52.53.155.43
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  182. May 2025
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