625 Matching Annotations
  1. Jan 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC10793589/
  3. www.nature.com www.nature.com
    A new genomic framework to categorize pediatric acute myeloid leukemia
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    nature.com/articles/s41588-023-01640-3
  4. www.sciencedirect.com www.sciencedirect.com
    Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
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    sciencedirect.com/science/article/pii/S1535610823004361
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10330305/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Discovery and validation of genes driving drug-intake and related behavioral traits in mice
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    onlinelibrary.wiley.com/doi/10.1111/gbb.12875
  7. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    sciencedirect.com/science/article/pii/S1550413123004618
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10758689/
  9. Dec 2023
  10. www.sciencedirect.com www.sciencedirect.com
    HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes
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    sciencedirect.com/science/article/pii/S2589004223027712
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722136/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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    ncbi.nlm.nih.gov/pmc/articles/PMC10722143/
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    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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    sciencedirect.com/science/article/pii/S1535610823004014
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10690093/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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    ncbi.nlm.nih.gov/pmc/articles/PMC10658995/
  16. 52.53.155.43 52.53.155.43
    cd-23-0299-html.html
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    52.53.155.43/2b6c279d82b7a0e0d491057f5790a1189e93077e/cd-23-0299-html.html
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  18. 52.53.155.43 52.53.155.43
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Short-chain-fatty acid valerate reduces voluntary alcohol intake in male mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC10635392/
  20. Nov 2023
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10680432/
  22. www.sciencedirect.com www.sciencedirect.com
    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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    sciencedirect.com/science/article/pii/S2451945623003847
  23. www.sciencedirect.com www.sciencedirect.com
    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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    sciencedirect.com/science/article/pii/S2666379123004846
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10643953/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair
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    ncbi.nlm.nih.gov/pmc/articles/PMC10644001/
  26. www.sciencedirect.com www.sciencedirect.com
    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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    sciencedirect.com/science/article/pii/S2211124723013839
  27. dx.doi.org dx.doi.org
    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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    dx.doi.org/10.1158/2767-9764.CRC-23-0165
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Factor-inhibiting HIF (FIH) promotes lung cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC10619494/
  29. Oct 2023
  30. www.sciencedirect.com www.sciencedirect.com
    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
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    sciencedirect.com/science/article/pii/S2211124723012688
  31. www.sciencedirect.com www.sciencedirect.com
    Mechanopathology of biofilm-like Mycobacterium tuberculosis cords
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    sciencedirect.com/science/article/pii/S0092867423010371
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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    ncbi.nlm.nih.gov/pmc/articles/PMC10551667/
  33. 52.53.155.43 52.53.155.43
    mct-22-0681-html.html
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    52.53.155.43/d35db28aa1e833dc8bdcaa7cf7e7e23e3392038d/mct-22-0681-html.html
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein kinase B (PKB/AKT) protects IDH-mutated glioma from ferroptosis via Nrf2
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    ncbi.nlm.nih.gov/pmc/articles/PMC10073324/
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10543973/
  36. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus
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    sciencedirect.com/science/article/pii/S1521661623005284
  37. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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    nature.com/articles/s41467-023-41927-x
  38. Sep 2023
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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    ncbi.nlm.nih.gov/pmc/articles/PMC10520325/
  40. Aug 2023
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10430781/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC10426551/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted single cell isolation of spontaneously escaping live melanoma cells for comparative transcriptomics
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    ncbi.nlm.nih.gov/pmc/articles/PMC10416804/
  44. 52.53.155.43 52.53.155.43
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  45. dx.doi.org dx.doi.org
    Protective effects of imeglimin and metformin combination therapy on β-cells in db/db male mice
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    dx.doi.org/10.1210/endocr/bqad095
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE
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    ncbi.nlm.nih.gov/pmc/articles/PMC10369854/
  47. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    sciencedirect.com/science/article/pii/S2211124723009385
  48. link.springer.com link.springer.com
    Quantitative proteomics profiling reveals the inhibition of trastuzumab antitumor efficacy by phosphorylated RPS6 in gastric carcinoma
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    link.springer.com/article/10.1007/s00280-023-04571-2
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC9898120/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of ANCO1 Expression Regulates Chromatin Accessibility and Drives Progression of Early-Stage Triple-Negative Breast Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10380654/
  51. Jul 2023
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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    ncbi.nlm.nih.gov/pmc/articles/PMC10366467/
  53. www.sciencedirect.com www.sciencedirect.com
    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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    sciencedirect.com/science/article/pii/S2211124723008021
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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    ncbi.nlm.nih.gov/pmc/articles/PMC10354099/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
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    ncbi.nlm.nih.gov/pmc/articles/PMC10355154/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC10320471/
  57. 52.53.155.43 52.53.155.43
    cd-22-0411-html.html
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    52.53.155.43/453457acda6208aed297e8061921a5c2d2ddddf2/cd-22-0411-html.html
  58. Jun 2023
  59. 52.53.155.43 52.53.155.43
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    52.53.155.43/726555d37fadfa1ef429cf94df3437d3f13c8b94/can-22-2712-html.html
  60. link.springer.com link.springer.com
    Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers
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    link.springer.com/article/10.1007/s11060-023-04359-7
  61. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic landscape of early hair follicle and epidermal development
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    sciencedirect.com/science/article/pii/S221112472300654X
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-infiltrating leukocyte profiling defines three immune subtypes of NSCLC with distinct signaling pathways and genetic alterations
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    ncbi.nlm.nih.gov/pmc/articles/PMC10263066/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10260022/
  64. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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    aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
  65. aacrjournals.org aacrjournals.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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    aacrjournals.org/mcr/article/21/5/444/726027/MYC-Glutamine-Dependency-Is-a-Therapeutic
  66. 52.53.155.43 52.53.155.43
    Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling
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    52.53.155.43/bed7a9208c54adf86acc18c446f54a38acbd010c/1-s2.0-S2589004223010891-main-html.html
  67. dx.doi.org dx.doi.org
    NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
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    dx.doi.org/10.1210/endocr/bqad073
  68. www.biorxiv.org www.biorxiv.org
    Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants
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    biorxiv.org/content/10.1101/2023.05.29.542774v1
  69. www.biorxiv.org www.biorxiv.org
    The lipid phosphatase activity of PTEN dampens FRA1 expression via AKT/mTOR signaling to suppress melanoma
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    biorxiv.org/content/10.1101/2023.06.01.543131v1
  70. aacrjournals.org aacrjournals.org
    A self-propagating c-Met-SOX2 axis drives cancer-derived IgG signaling that promotes lung cancer cell stemness
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    aacrjournals.org/cancerres/article/83/11/1866/726450/A-Self-Propagating-c-Met-SOX2-Axis-Drives-Cancer
  71. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  72. 52.53.155.43 52.53.155.43
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  73. May 2023
  74. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    sciencedirect.com/science/article/pii/S2211124723005478
  75. www.nature.com www.nature.com
    Targeting metabolism by B-raf inhibitors and diclofenac restrains the viability of BRAF-mutated thyroid carcinomas with Hif-1α-mediated glycolytic phenotype
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    nature.com/articles/s41416-023-02282-2
  76. www.sciencedirect.com www.sciencedirect.com
    Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
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    sciencedirect.com/science/article/pii/S2211124723004850
  77. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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    onlinelibrary.wiley.com/doi/10.1002/advs.202206098
  78. www.sciencedirect.com www.sciencedirect.com
    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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    sciencedirect.com/science/article/pii/S1534580723001806
  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification related to immunogenic cell death predicts prognosis, immune microenvironment characteristics, and response to immunotherapy in lower-grade gliomas
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    ncbi.nlm.nih.gov/pmc/articles/PMC10154552/
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes
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    ncbi.nlm.nih.gov/pmc/articles/PMC10150248/
  81. Apr 2023
  82. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    sciencedirect.com/science/article/pii/S1097276523002496
  83. link.springer.com link.springer.com
    Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways
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    link.springer.com/article/10.1038/s41598-023-33096-0
  84. aacrjournals.org aacrjournals.org
    Single-cell transcriptomics reveals immune reconstitution in R/R T-ALL/LBL patients with donor-derived CD7 CAR-T therapy
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    aacrjournals.org/clincancerres/article/29/8/1484/725068/Single-Cell-Transcriptomics-Reveals-Immune
  85. aacrjournals.org aacrjournals.org
    IL-18 receptor signaling regulates tumor-reactive CD8+ T-cell exhaustion via activation of the IL-2/STAT5/mTOR pathway in a pancreatic cancer model
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    aacrjournals.org/cancerimmunolres/article/11/4/421/718978/IL18-Receptor-Signaling-Regulates-Tumor-Reactive
  86. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    aacrjournals.org/cancerimmunolres/article/11/3/381/716712/Cancer-Cell-Resistance-to-IFN-Can-Occur-via
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon
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    ncbi.nlm.nih.gov/pmc/articles/PMC10046350/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation
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    ncbi.nlm.nih.gov/pmc/articles/PMC10064239/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9971359/
  90. Mar 2023
  91. www.sciencedirect.com www.sciencedirect.com
    A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans
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    sciencedirect.com/science/article/pii/S1074761323000948
  92. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    sciencedirect.com/science/article/pii/S1097276523001533
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing mRNA signatures as a novel prognostic biomarker predicting high risk multiple myeloma
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    ncbi.nlm.nih.gov/pmc/articles/PMC9995860/
  94. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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    sciencedirect.com/science/article/pii/S2666979X23000368
  95. www.sciencedirect.com www.sciencedirect.com
    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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  175. Feb 2022
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  181. Jan 2022
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  185. Dec 2021
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  192. Nov 2021
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