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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genomic and transcriptomic landscape of human gastrointestinal stromal tumors
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    1. scibot 21 Dec 2024
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      DOI: 10.1038/s41467-024-53821-1

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532483/
  3. www.sciencedirect.com www.sciencedirect.com
    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    1. scibot 21 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.031

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    sciencedirect.com/science/article/pii/S1097276524009560
  4. 52.53.155.43 52.53.155.43
    ccr-24-0427-html.html
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    1. scibot 19 Dec 2024
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      DOI: 10.1158/1078-0432.ccr-24-0427

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    2. scibot 17 Dec 2024
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      DOI: 10.1158/1078-0432.ccr-24-0427

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  5. Dec 2024
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neural precursor cells rescue symptoms of Rett syndrome by activation of the Interferon γ pathway
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    1. scibot 13 Dec 2024
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      DOI: 10.1038/s44321-024-00144-9

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    pmc.ncbi.nlm.nih.gov/articles/PMC11628625/
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MYC Drives mRNA Pseudouridylation to Mitigate Proliferation-Induced Cellular Stress during Cancer Development
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    1. scibot 12 Dec 2024
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      DOI: 10.1158/0008-5472.CAN-24-1102

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609627/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    1. scibot 11 Dec 2024
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      DOI: 10.1158/2159-8290.CD-23-0866

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    pmc.ncbi.nlm.nih.gov/articles/PMC11609823/
  9. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.molcel.2024.11.009

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    sciencedirect.com/science/article/pii/S1097276524009146
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
    1
    1. scibot 05 Dec 2024
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      DOI: 10.1016/j.celrep.2024.115026

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    sciencedirect.com/science/article/pii/S2211124724013779
  11. www.mdpi.com www.mdpi.com
    Discovery, Validation and Mechanistic Study of XPO1 Inhibition in the Treatment of Triple-Negative Breast Cancer
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    1. scibot 04 Dec 2024
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      DOI: 10.3390/cancers16233980

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    mdpi.com/2072-6694/16/23/3980
  12. www.science.org www.science.org
    Coordination between the eIF2 kinase GCN2 and p53 signaling supports purine metabolism and the progression of prostate cancer
    1
    1. scibot 03 Dec 2024
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      DOI: 10.1126/scisignal.adp1375

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    science.org/doi/10.1126/scisignal.adp1375
  13. www.sciencedirect.com www.sciencedirect.com
    Flt3L enhances clonal diversification and selective expansion of intratumoral CD8+ T cells while differentiating into effector-like cells
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    1. scibot 02 Dec 2024
      RRID:SCR_003199

      DOI: 10.1016/j.celrep.2024.115023

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    sciencedirect.com/science/article/pii/S2211124724013743
  14. Nov 2024
  15. www.sciencedirect.com www.sciencedirect.com
    Eriocitrin ameliorates hepatic fibrosis and inflammation: The involvement of PPARα-mediated NLRP1/NLRC4 inflammasome signaling cascades
    1
    1. scibot 24 Nov 2024
      Gene Set Enrichment Analysis

      DOI: 10.1016/j.jep.2024.119119

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    sciencedirect.com/science/article/pii/S0378874124014181
  16. 52.53.155.43 52.53.155.43
    cir-24-0324-html.html
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    1. scibot 14 Nov 2024
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      DOI: 10.1158/2326-6066.cir-24-0324

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  17. 52.53.155.43 52.53.155.43
    ccr-24-1240-html.html
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    1. scibot 14 Nov 2024
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      DOI: 10.1158/1078-0432.ccr-24-1240

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  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Blood-Based microRNA Biomarker Signature of Early-Stage Pancreatic Ductal Adenocarcinoma With Lead-Time Trajectory in Prediagnostic Samples
    1
    1. scibot 14 Nov 2024
      RRID:SCR_003199

      DOI: 10.1016/j.gastha.2024.08.002

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    pmc.ncbi.nlm.nih.gov/articles/PMC11550741/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High TNF and NF-κB Pathway Dependency Are Associated with AZD5582 Sensitivity in OSCC via CASP8-Dependent Apoptosis
    1
    1. scibot 13 Nov 2024
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      DOI: 10.1158/2767-9764.CRC-24-0136

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    pmc.ncbi.nlm.nih.gov/articles/PMC11551840/
  20. 52.53.155.43 52.53.155.43
    mcr-24-0490-html.html
    1
    1. scibot 08 Nov 2024
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      DOI: 10.1158/1541-7786.mcr-24-0490

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  21. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
    1
    1. scibot 08 Nov 2024
      RRID:SCR_003199

      DOI: 10.1158/0008-5472.CAN-24-0134

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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
  22. 52.53.155.43 52.53.155.43
    can-24-0886-html.html
    2
    1. scibot 07 Nov 2024
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      DOI: 10.1158/0008-5472.can-24-0886

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    2. scibot 07 Nov 2024
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      DOI: 10.1158/0008-5472.can-24-0886

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    52.53.155.43/656f4a916577efff373ec46750afc04546654778/can-24-0886-html.html
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial apolipoprotein MIC26 is a metabolic rheostat regulating central cellular fuel pathways
    1
    1. scibot 07 Nov 2024
      RRID:SCR_003199

      DOI: 10.26508/lsa.202403038

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    ncbi.nlm.nih.gov/pmc/articles/PMC11472510/
  24. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Omics-driven investigation of the biology underlying intrinsic submaximal working capacity and its trainability
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    1. scibot 07 Nov 2024
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      DOI: 10.1152/physiolgenomics.00163.2022

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    pmc.ncbi.nlm.nih.gov/articles/PMC11178266/
  25. Oct 2024
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
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    1. scibot 05 Oct 2024
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      DOI: 10.1016/j.chembiol.2023.06.016

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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  27. aacrjournals.org aacrjournals.org
    2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
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    1. scibot 02 Oct 2024
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      DOI: 10.1158/0008-5472.CAN-20-1517

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    aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
  28. Sep 2024
  29. www.biorxiv.org www.biorxiv.org
    A Comprehensive Proteogenomic and Spatial Analysis of Innate and Acquired Resistance of Metastatic Melanoma to Immune Checkpoint Blockade Therapies
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    1. scibot 29 Sep 2024
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      DOI: 10.1101/2024.09.12.612675

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    biorxiv.org/content/10.1101/2024.09.12.612675v1
  30. www.sciencedirect.com www.sciencedirect.com
    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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    1. scibot 26 Sep 2024
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      DOI: 10.1016/j.xgen.2024.100659

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    sciencedirect.com/science/article/pii/S2666979X24002702
  31. www.sciencedirect.com www.sciencedirect.com
    Lysosome-related organelle integrity suppresses TIR-1 aggregation to restrain toxic propagation of p38 innate immunity
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114674

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    sciencedirect.com/science/article/pii/S2211124724010258
  32. www.sciencedirect.com www.sciencedirect.com
    Oncogenic Notch Promotes Long-Range Regulatory Interactions within Hyperconnected 3D Cliques
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    1. scibot 25 Sep 2024
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      DOI: 10.1016/j.molcel.2019.01.006

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    sciencedirect.com/science/article/pii/S1097276519300061
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL36G-producing neutrophil-like monocytes promote cachexia in cancer
    1
    1. scibot 18 Sep 2024
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      DOI: 10.1038/s41467-024-51873-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC11393454/
  34. www.sciencedirect.com www.sciencedirect.com
    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    1. scibot 05 Sep 2024
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      DOI: 10.1016/j.immuni.2024.08.008

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    sciencedirect.com/science/article/pii/S1074761324004072
  35. www.sciencedirect.com www.sciencedirect.com
    MAML3-fusions modulate vascular and immune tumour microenvironment and confer high metastatic risk in pheochromocytoma and paraganglioma
    1
    1. scibot 04 Sep 2024
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      DOI: 10.1016/j.beem.2024.101931

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    sciencedirect.com/science/article/pii/S1521690X24001064
  36. Aug 2024
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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      DOI: 10.1158/2767-9764.CRC-24-0214

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    ncbi.nlm.nih.gov/pmc/articles/PMC11350481/
  38. www.sciencedirect.com www.sciencedirect.com
    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
    1
    1. scibot 27 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114681

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    sciencedirect.com/science/article/pii/S2211124724010325
  39. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
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      DOI: 10.1016/j.stem.2024.07.009

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    sciencedirect.com/science/article/pii/S1934590924002856
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cadmium activation of wild-type and constitutively active estrogen receptor alpha
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    1. scibot 26 Aug 2024
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      DOI: 10.3389/fendo.2024.1380047

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    ncbi.nlm.nih.gov/pmc/articles/PMC11341946/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Contribution and Clinical Implication of Cancer-Associated Fibroblasts in Glioblastoma
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    1. scibot 22 Aug 2024
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      DOI: 10.1158/1078-0432.CCR-23-0493

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    ncbi.nlm.nih.gov/pmc/articles/PMC10922678/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transient Differentiation-State Plasticity Occurs During Acute Lymphoblastic Leukemia Initiation
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    1. scibot 22 Aug 2024
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      DOI: 10.1158/0008-5472.CAN-24-1090

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    ncbi.nlm.nih.gov/pmc/articles/PMC11325147/
  43. www.sciencedirect.com www.sciencedirect.com
    Epithelial organoid supports resident memory CD8 T cell differentiation
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    1. scibot 22 Aug 2024
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      DOI: 10.1016/j.celrep.2024.114621

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    sciencedirect.com/science/article/pii/S2211124724009719
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53R172H and p53R245W Hotspot Mutations Drive Distinct Transcriptomes in Mouse Mammary Tumors Through a Convergent Transcriptional Mediator
    1
    1. scibot 21 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0128

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    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    BCL6 confers resistance to HDAC inhibitors in DLBCL
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    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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    Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    Identification of immunosenescence of unconventional T cells in hepatocellular carcinoma
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    A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle
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    RNF185 control of COL3A1 expression limits prostate cancer migration and metastatic potential
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    Loss of ADAM29 does not affect viability and fertility in mice but improves wound healing
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  56. Jun 2024
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    The clock gene BHLHE40 and atypical CCNG2 control androgen-induced cellular senescence as a novel tumor suppressive pathway in prostate cancer
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    A chronic signaling TGFb zebrafish reporter identifies immune response in melanoma
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    Surgical tumour resection deregulates Hallmarks of Cancer in resected tissue and the surrounding microenvironment
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    Obesogenic High-Fat Diet and MYC Cooperate to Promote Lactate Accumulation and Tumor Microenvironment Remodeling in Prostate Cancer
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    Memory/Active T-Cell Activation Is Associated with Immunotherapeutic Response in Fumarate Hydratase–Deficient Renal Cell Carcinoma
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    NR4A1 transcriptionally regulates the differentiation of stem-like CD8+ T cells in the tumor microenvironment
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  64. May 2024
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    A cocktail of rapamycin, acarbose, and phenylbutyrate prevents age-related cognitive decline in mice by targeting multiple aging pathways
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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    Targeting ferroptosis-elicited inflammation suppresses hepatocellular carcinoma metastasis and enhances sorafenib efficacy
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    The CD8+ T cell tolerance checkpoint triggers a distinct differentiation state defined by protein translation defects
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    Immunotherapy-activated T cells recruit and skewlate-stage activated M1-like macrophagesthat are critical for therapeutic efficacy
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    A phosphate transporter in VIPergic neurons of the suprachiasmatic nucleus gates locomotor activity during the light/dark transition in mice
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    The MYCN oncoprotein is an RNA-binding accessory factor of the nuclear exosome targeting complex
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    MILIP Binding to tRNAs Promotes Protein Synthesis to Drive Triple-Negative Breast Cancer
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  78. Apr 2024
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    Spatial and temporal mapping of breast cancer lung metastases identify TREM2 macrophages as regulators of the metastatic boundary
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    Class I HDAC inhibitors enhance antitumor efficacy and persistence of CAR-T cells by activation of the Wnt pathway
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    A senescence restriction point acting on chromatin integrates oncogenic signals
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    Telomere dysfunction alters intestinal stem cell dynamics to promote cancer
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  84. Mar 2024
  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Novel HOXA10-Associated 5 Gene-Based Prognostic Signature for Stratification of Short-Term Survivors of Pancreatic Ductal Adenocarcinoma
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    Acetyl-CoA carboxylase obstructs CD8+ T cell lipid utilization in the tumor microenvironment
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    Mecp2 knock-out astrocytes affect synaptogenesis by Interleukin 6 dependent mechanisms
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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    De novo and histologically transformed small cell lung cancer is sensitive to lurbinectedin treatment through the modulation of EMT and NOTCH signaling pathways
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  89. Feb 2024
  90. aacrjournals.org aacrjournals.org
    A novel irreversible TEAD inhibitor, SWTX-143, blocks Hippo pathway transcriptional output and causes tumor regression in preclinical mesothelioma models
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      DOI: 10.1158/1535-7163.MCT-22-0681

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    aacrjournals.org/mct/article/23/1/3/732154/A-Novel-Irreversible-TEAD-Inhibitor-SWTX-143
  91. aacrjournals.org aacrjournals.org
    TEAD Inhibition Overcomes YAP1/TAZ-driven Primary and Acquired Resistance to KRASG12C Inhibitors
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    aacrjournals.org/cancerres/article/83/24/4112/731546/TEAD-Inhibition-Overcomes-YAP1-TAZ-Driven-Primary
  92. aacrjournals.org aacrjournals.org
    RNA methyltransferase FTSJ3 regulates the type I interferon pathway to promote hepatocellular carcinoma immune evasion
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  93. 52.53.155.43 52.53.155.43
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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant p53 protects triple-negative breast adenocarcinomas from ferroptosis in vivo
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  95. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting BET proteins downregulates miR-33a to promote synergy with PIM inhibitors in CMML
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Immunogenomic Landscape of Neuroendocrine Prostate Cancer
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  98. Jan 2024
  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glucose Deprivation Promotes Pseudohypoxia and Dedifferentiation in Lung Adenocarcinoma
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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O6-Methylguanine DNA Methyltransferase Regulates β-glucan-induced Trained Immunity of Macrophages via Farnesoid X Receptor and AMPK
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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion
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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Differential Regulation of the Stimulator of Interferon Genes pathway in Human Papillomavirus positive and negative Head and Neck Cancers
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  103. www.nature.com www.nature.com
    A new genomic framework to categorize pediatric acute myeloid leukemia
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  104. www.sciencedirect.com www.sciencedirect.com
    Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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  106. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Discovery and validation of genes driving drug-intake and related behavioral traits in mice
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  107. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging tissue-specific enhancer-target gene regulatory networks identifies enhancer somatic mutations that functionally impact lung cancer
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  109. Dec 2023
  110. www.sciencedirect.com www.sciencedirect.com
    HAMSAB diet ameliorates dysfunctional signaling in pancreatic islets in autoimmune diabetes
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  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FGFR3 alterations in bladder cancer stimulate serine synthesis to induce immune-inert macrophages that suppress T-cell recruitment and activation
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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Topoisomerase 1 Inhibition in MYC-Driven Cancer Promotes Aberrant R-Loop Accumulation to Induce Synthetic Lethality
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      DOI: 10.1158/0008-5472.CAN-22-2948

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  113. www.sciencedirect.com www.sciencedirect.com
    Integrated multi-omics profiling to dissect the spatiotemporal evolution of metastatic hepatocellular carcinoma
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fatty Acid Oxidation Mediated by Malonyl-CoA Decarboxylase Represses Renal Cell Carcinoma Progression
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia potentiates the inflammatory fibroblast phenotype promoted by pancreatic cancer cell-derived cytokines
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  116. 52.53.155.43 52.53.155.43
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  117. 52.53.155.43 52.53.155.43
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Short-chain-fatty acid valerate reduces voluntary alcohol intake in male mice
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      DOI: 10.21203/rs.3.rs-3496323/v1

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  120. Nov 2023
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    SIX4 Controls Anti-PD-1 Efficacy by Regulating STING Expression
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    PIM1 targeted degradation prevents the emergence of chemoresistance in prostate cancer
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      DOI: 10.1016/j.chembiol.2023.10.023

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    Allosteric SHP2 inhibition increases apoptotic dependency on BCL2 and synergizes with venetoclax in FLT3- and KIT-mutant AML
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      DOI: 10.1016/j.xcrm.2023.101290

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL23R as an indicator of immune infiltration and poor prognosis in intrahepatic cholangiocarcinoma: a bioinformatics analysis
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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Entinostat Enhances the Efficacy of Chemotherapy in Small Cell Lung Cancer Through S-phase Arrest and Decreased Base Excision Repair
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  126. www.sciencedirect.com www.sciencedirect.com
    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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  127. dx.doi.org dx.doi.org
    Population-specific Mutation Patterns in Breast Tumors from African American, European American, and Kenyan Patients
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Factor-inhibiting HIF (FIH) promotes lung cancer progression
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      DOI: 10.1172/jci.insight.167394

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  129. Oct 2023
  130. www.sciencedirect.com www.sciencedirect.com
    Differential DNA damage repair and PARP inhibitor vulnerability of the mammary epithelial lineages
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      DOI: 10.1016/j.celrep.2023.113256

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  131. www.sciencedirect.com www.sciencedirect.com
    Mechanopathology of biofilm-like Mycobacterium tuberculosis cords
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Colorectal Cancer Organoid–Stroma Biobank Allows Subtype-Specific Assessment of Individualized Therapy Responses
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  133. 52.53.155.43 52.53.155.43
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein kinase B (PKB/AKT) protects IDH-mutated glioma from ferroptosis via Nrf2
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      DOI: 10.1158/1078-0432.CCR-22-3179

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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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      DOI: 10.1158/1078-0432.CCR-22-3396

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    Transcriptomic and proteomic profiling reveals distinct pathogenic features of peripheral non-classical monocytes in systemic lupus erythematosus
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    sciencedirect.com/science/article/pii/S1521661623005284
  137. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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      DOI: 10.1038/s41467-023-41927-x

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  138. Sep 2023
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Myeloid leukemia vulnerabilities embedded in long noncoding RNA locus MYNRL15
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  140. Aug 2023
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated single cell and bulk sequencing analysis identifies tumor reactive CXCR6+ CD8 T cells as a predictor of immune infiltration and immunotherapy outcomes in hepatocellular carcinoma
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Kinase Inhibitor Pulldown Assay Identifies a Chemotherapy Response Signature in Triple-negative Breast Cancer Based on Purine-binding Proteins
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted single cell isolation of spontaneously escaping live melanoma cells for comparative transcriptomics
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  144. 52.53.155.43 52.53.155.43
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  145. dx.doi.org dx.doi.org
    Protective effects of imeglimin and metformin combination therapy on β-cells in db/db male mice
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      DOI: 10.1210/endocr/bqad095

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  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DISCOVERY AND VALIDATION OF GENES DRIVING DRUG-INTAKE AND RELATED BEHAVIORAL TRAITS IN MICE
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      DOI: 10.1101/2023.07.09.548280

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    ncbi.nlm.nih.gov/pmc/articles/PMC10369854/
  147. www.sciencedirect.com www.sciencedirect.com
    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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  148. link.springer.com link.springer.com
    Quantitative proteomics profiling reveals the inhibition of trastuzumab antitumor efficacy by phosphorylated RPS6 in gastric carcinoma
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      DOI: 10.1007/s00280-023-04571-2

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    link.springer.com/article/10.1007/s00280-023-04571-2
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BET Inhibitors Target the SCLC-N subtype of Small Cell Lung Cancer by Blocking NEUROD1 Transactivation
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      DOI: 10.1158/1541-7786.MCR-22-0594

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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of ANCO1 Expression Regulates Chromatin Accessibility and Drives Progression of Early-Stage Triple-Negative Breast Cancer
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      DOI: 10.3390/ijms241411505

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    ncbi.nlm.nih.gov/pmc/articles/PMC10380654/
  151. Jul 2023
  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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      DOI: 10.1016/j.isci.2023.107231

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  153. www.sciencedirect.com www.sciencedirect.com
    FOXC2 promotes vasculogenic mimicry and resistance to anti-angiogenic therapy
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      DOI: 10.1016/j.celrep.2023.112791

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness
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      DOI: 10.1038/s41392-023-01487-4

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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A network-based approach reveals long non-coding RNAs associated with disease activity in lupus nephritis: key pathways for flare and potential biomarkers to be used as liquid biopsies
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      DOI: 10.3389/fimmu.2023.1203848

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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caffeine supplementation and FOXM1 inhibition enhance the antitumor effect of statins in neuroblastoma
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      DOI: 10.1158/0008-5472.CAN-22-3450

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  157. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/2159-8290.cd-22-0411

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  158. Jun 2023
  159. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/0008-5472.CAN-22-2712

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  160. link.springer.com link.springer.com
    Integrated clinical genomic analysis reveals xenobiotic metabolic genes are downregulated in meningiomas of current smokers
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      DOI: 10.1007/s11060-023-04359-7

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  161. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic landscape of early hair follicle and epidermal development
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor-infiltrating leukocyte profiling defines three immune subtypes of NSCLC with distinct signaling pathways and genetic alterations
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      DOI: 10.1158/2767-9764.CRC-22-0415

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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pancreatic tumors exhibit myeloid-driven amino acid stress and upregulate arginine biosynthesis
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      DOI: 10.7554/eLife.81289

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  164. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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      DOI: 10.1158/2159-8290.CD-22-0825

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    aacrjournals.org/cancerdiscovery/article/13/6/1478/726967/R-2-Hydroxyglutarate-Inhibits-KDM5-Histone-Lysine
  165. aacrjournals.org aacrjournals.org
    MYC/glutamine dependency is a therapeutic vulnerability in pancreatic cancer with deoxycytidine kinase inactivation-induced gemcitabine resistance
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      DOI: 10.1158/1541-7786.MCR-22-0554

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    aacrjournals.org/mcr/article/21/5/444/726027/MYC-Glutamine-Dependency-Is-a-Therapeutic
  166. 52.53.155.43 52.53.155.43
    Interferon hyperactivity impairs cardiogenesis in Down syndrome via downregulation of canonical Wnt signaling
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      DOI: 10.1016/j.isci.2023.107012

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  167. dx.doi.org dx.doi.org
    NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
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      DOI: 10.1210/endocr/bqad073

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  168. www.biorxiv.org www.biorxiv.org
    Human plasma-like medium facilitates metabolic tracing and enables upregulation of immune signaling pathways in glioblastoma explants
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      DOI: 10.1101/2023.05.29.542774

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    biorxiv.org/content/10.1101/2023.05.29.542774v1
  169. www.biorxiv.org www.biorxiv.org
    The lipid phosphatase activity of PTEN dampens FRA1 expression via AKT/mTOR signaling to suppress melanoma
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      DOI: 10.1101/2023.06.01.543131

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  170. aacrjournals.org aacrjournals.org
    A self-propagating c-Met-SOX2 axis drives cancer-derived IgG signaling that promotes lung cancer cell stemness
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      DOI: 10.1158/0008-5472.CAN-22-2733

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    aacrjournals.org/cancerres/article/83/11/1866/726450/A-Self-Propagating-c-Met-SOX2-Axis-Drives-Cancer
  171. aacrjournals.org aacrjournals.org
    Enhanced glutaminolysis drives hypoxia-induced chemoresistance in pancreatic cancer
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      DOI: 10.1158/0008-5472.CAN-22-2045

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    aacrjournals.org/cancerres/article/83/5/735/716680/Enhanced-Glutaminolysis-Drives-Hypoxia-Induced
  172. 52.53.155.43 52.53.155.43
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  173. May 2023
  174. www.sciencedirect.com www.sciencedirect.com
    AKT activation because of PTEN loss upregulates xCT via GSK3β/NRF2, leading to inhibition of ferroptosis in PTEN-mutant tumor cells
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    sciencedirect.com/science/article/pii/S2211124723005478
  175. www.nature.com www.nature.com
    Targeting metabolism by B-raf inhibitors and diclofenac restrains the viability of BRAF-mutated thyroid carcinomas with Hif-1α-mediated glycolytic phenotype
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    nature.com/articles/s41416-023-02282-2
  176. www.sciencedirect.com www.sciencedirect.com
    Vaginal epithelial dysfunction is mediated by the microbiome, metabolome, and mTOR signaling
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  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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      DOI: 10.1002/advs.202206098

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    Immune mechanisms shape the clonal landscape during early progression of prostate cancer
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification related to immunogenic cell death predicts prognosis, immune microenvironment characteristics, and response to immunotherapy in lower-grade gliomas
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  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep Transcriptome Profiling of Multiple Myeloma Using Quantitative Phenotypes
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      DOI: 10.1158/1055-9965.EPI-22-0798

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  181. Apr 2023
  182. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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    1. scibot 29 Apr 2023
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    sciencedirect.com/science/article/pii/S1097276523002496
  183. link.springer.com link.springer.com
    Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways
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  184. aacrjournals.org aacrjournals.org
    Single-cell transcriptomics reveals immune reconstitution in R/R T-ALL/LBL patients with donor-derived CD7 CAR-T therapy
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    aacrjournals.org/clincancerres/article/29/8/1484/725068/Single-Cell-Transcriptomics-Reveals-Immune
  185. aacrjournals.org aacrjournals.org
    IL-18 receptor signaling regulates tumor-reactive CD8+ T-cell exhaustion via activation of the IL-2/STAT5/mTOR pathway in a pancreatic cancer model
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    1. scibot 21 Apr 2023
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      DOI: 10.1158/2326-6066.CIR-22-0398

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    aacrjournals.org/cancerimmunolres/article/11/4/421/718978/IL18-Receptor-Signaling-Regulates-Tumor-Reactive
  186. aacrjournals.org aacrjournals.org
    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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      DOI: 10.1158/2326-6066.CIR-22-0056

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  187. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Analysis of Cancer Genomic Amplifications Identifies Druggable Collateral Dependencies within the Amplicon
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    1. scibot 05 Apr 2023
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      DOI: 10.3390/cancers15061636

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  188. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PGC-1s shape epidermal physiology by modulating keratinocyte proliferation and terminal differentiation
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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gain of chromosome 1q perturbs a competitive endogenous RNA network to promote melanoma metastasis
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    1. scibot 04 Apr 2023
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      DOI: 10.1158/0008-5472.CAN-22-0283

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  190. Mar 2023
  191. www.sciencedirect.com www.sciencedirect.com
    A transcriptionally distinct subset of influenza-specific effector memory B cells predicts long-lived antibody responses to vaccination in humans
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      DOI: 10.1016/j.immuni.2023.03.001

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    sciencedirect.com/science/article/pii/S1074761323000948
  192. www.sciencedirect.com www.sciencedirect.com
    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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      DOI: 10.1016/j.molcel.2023.02.026

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  193. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developing mRNA signatures as a novel prognostic biomarker predicting high risk multiple myeloma
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  194. www.sciencedirect.com www.sciencedirect.com
    In vivo interrogation of regulatory genomes reveals extensive quasi-insufficiency in cancer evolution
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      DOI: 10.1016/j.xgen.2023.100276

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    sciencedirect.com/science/article/pii/S2666979X23000368
  195. www.sciencedirect.com www.sciencedirect.com
    Linoleic acid potentiates CD8+ T cell metabolic fitness and antitumor immunity
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      DOI: 10.1016/j.cmet.2023.02.013

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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genomic and immune landscape Of metastatic pheochromocytoma and paraganglioma
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      DOI: 10.1038/s41467-023-36769-6

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  197. Feb 2023
  198. link.springer.com link.springer.com
    Bridging Health Disparities: a Genomics and Transcriptomics Analysis by Race in Prostate Cancer
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      RRID:SCR_003199

      DOI: 10.1007/s40615-023-01534-4

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  199. www.sciencedirect.com www.sciencedirect.com
    Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans
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      DOI: 10.1016/j.immuni.2023.01.027

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    sciencedirect.com/science/article/pii/S1074761323000390
  200. 52.53.155.43 52.53.155.43
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      DOI: 10.1158/1541-7786.mcr-22-0594

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  201. www.sciencedirect.com www.sciencedirect.com
    A fetal tumor suppressor axis abrogates MLL-fusion-driven acute myeloid leukemia
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      DOI: 10.1016/j.celrep.2023.112099

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  202. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of PBRM1 alters promoter histone modifications and activates ALDH1A1 to drive renal cell carcinoma
    1
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      DOI: 10.1158/1541-7786.MCR-21-1039

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  203. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stromal p53 Regulates Breast Cancer Development, the Immune Landscape, and Survival in an Oncogene-Specific Manner
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      DOI: 10.1158/1541-7786.MCR-21-0960

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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
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      DOI: 10.1158/2643-3230.BCD-21-0160

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    Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells
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    S100A9 promotes glycolytic activity in HER2-positive breast cancer to induce immunosuppression in the tumour microenvironment
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      DOI: 10.1016/j.heliyon.2023.e13294

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  207. Jan 2023
  208. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
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      DOI: 10.3389/fimmu.2022.1057421

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  209. aacrjournals.org aacrjournals.org
    Spatial transcriptomic analysis of a diverse patient cohort reveals a conserved architecture in triple-negative breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-2682

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    aacrjournals.org/cancerres/article/83/1/34/711842/Spatial-Transcriptomic-Analysis-of-a-Diverse
  210. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapy-induced senescence enhances the efficacy of HER2-targeted antibody-drug conjugates in breast cancer
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      DOI: 10.1158/0008-5472.CAN-22-0787

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  211. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PDIA3 Activity Promotes Extracellular Accumulation of Proteins Relevant to Basal Breast Cancer Outcomes in Human MDA-MB-A231 Breast Cancer Cells
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      DOI: 10.1152/ajpcell.00445.2022

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  212. www.sciencedirect.com www.sciencedirect.com
    Transcriptomic profiling reveals sex-specific molecular signatures of adipose endothelial cells under obesogenic conditions
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      DOI: 10.1016/j.isci.2022.105811

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  213. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor
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      DOI: 10.1158/2159-8290.CD-21-0646

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  214. Dec 2022
  215. link.springer.com link.springer.com
    AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
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      DOI: 10.1007/s00018-022-04638-y

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  216. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Anti-cancer activity of ST101, a novel antagonist of CCAAT/enhancer binding protein β
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      DOI: 10.1158/1535-7163.MCT-21-0962

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