3,159 Matching Annotations
  1. Jul 2025
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A human neuron alzheimer’s disease model reveals barriers to senolytic translatability
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297865/
  3. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PLT012, a humanized CD36-blocking antibody, is effective for unleashing anti-tumor immunity against liver cancer and liver metastasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617665/
  4. 52.53.155.43 52.53.155.43
    Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice
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    52.53.155.43/4962c8654320fb21d270a9a33cb9a80f745af745/shim-et-al-2023-inhibition-of-glutaminase-1-activity-reverses-airway-hyperresponsiveness-and-decreases-il-1-m1s-and-il (1)-html.html
  5. www.biorxiv.org www.biorxiv.org
    RUNX2 inhibition disrupts a PAX3::FOXO1-RUNX2 feed-forward loop and dismantles oncogenic gene programs in fusion-positive rhabdomyosarcoma
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    biorxiv.org/content/10.1101/2025.07.21.665972v1
  6. rupress.org rupress.org
    Ubiquitin chain variability directs substrates of the Tul1 ubiquitin ligase complex to different degradation pathways
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    rupress.org/jcb/article/224/9/e202312133/278137/Ubiquitin-chain-variability-directs-substrates-of
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    Chimeric antigen receptor T cells in treatment-refractory DAGLA antibody-associated encephalitis
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    cell.com/med/abstract/S2666-6340(25)00203-X
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    Asynchronous aging and turnover of human circulating and tissue-resident memory T cells across sites
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    sciencedirect.com/science/article/pii/S1074761325003103
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    MyD88 polymerization and association to cellular membranes in a yeast heterologous model
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    pmc.ncbi.nlm.nih.gov/articles/PMC12297185/
  10. 52.53.155.43 52.53.155.43
    41556_2025_1712_MOESM4_ESM-html.html
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    Direct transdifferentiation of tumorigenic melanoma cells induces tumor cell reversion
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    nature.com/articles/s41419-025-07863-y
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    Therapeutic targeting of syndecan-1 axis overcomes acquired resistance to KRAS-targeted therapy in gastrointestinal cancers
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    sciencedirect.com/science/article/pii/S266637912500326X
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    Loss of Predicted Cell Adhesion Molecule MPZL3 Promotes EMT in Ovarian Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12277487/
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    Acute BRCAness induction and AR pathway blockage through CDK12/7/9 degradation enhances PARP inhibitor sensitivity in prostate cancer
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    science.org/doi/10.1126/sciadv.adu0847
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    Novel Aptamer-Drug Conjugate for Targeted Therapy in Triple-Negative Breast Cancer
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    pubs.acs.org/doi/full/10.1021/acs.jmedchem.5c00492
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    MSN/STAT3 drives cancer stemness and chemoresistance via IL-6/LPAR1 ligand receptor complex in triple-negative breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12281688/
  17. journals.physiology.org journals.physiology.org
    Inhibition of glutaminase 1 activity reverses airway hyperresponsiveness and decreases IL-1β+ M1s and IL-17 producing ILC3s in high-fat diet-fed obese mice
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    journals.physiology.org/doi/10.1152/ajplung.00181.2022
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    Targeting Triple-Negative Breast Cancer with Momordicine-I for Therapeutic Gain in Preclinical Models
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    mdpi.com/2072-6694/17/14/2342
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    Cellular crosstalk mediated by TGF-β drives epithelial-mesenchymal transition in patient-derived multi-compartment biliary organoids
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    nature.com/articles/s41467-025-61442-5
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  21. 52.53.155.43 52.53.155.43
    MyoD is Essential in Rhabdomyosarcoma by Promoting Survival Through Differentiation and CYLD
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    Tuning antibody stability and function by rational designs of framework mutations
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    pmc.ncbi.nlm.nih.gov/articles/PMC12269682/
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    SLC7A11 protects amoeboid-disseminating cancer cells from oxidative stress
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    Nostoc commune-derived scytonemin induced mitochondrial cell death in leukemia models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12267311/
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    The Integrated Stress Response Pathway Coordinates Translational Control of Multiple Immune Checkpoints in Lung Cancer
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    Monoallelic mutations in MMD2 cause autosomal dominant aggressive periodontitis
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    TAF1 is required for fetal but not adult hematopoiesis in mice
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    sciencedirect.com/science/article/pii/S1534580725004058
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    Genetic and pharmacological targeting of nicotinic acetylcholine receptor action blocks tumor progression in mouse models of breast cancer
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    dx.doi.org/10.1093/jimmun/vkaf148
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    Ce6 derivative photodynamic therapy triggers PANoptosis and enhances antitumor immunity with LAG3 blockade in cutaneous squamous cell carcinoma
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    sciencedirect.com/science/article/pii/S266637912500312X
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    A developmental program of early residency promotes the differentiation of divergent uterine NK cell subsets in humans
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    biorxiv.org/content/10.1101/2025.07.05.663267v1
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    Inhibition of the minor spliceosome restricts the growth of a broad spectrum of cancers
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    embopress.org/doi/10.1038/s44319-025-00511-8
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    Constitutive interaction between neutrophils and von Willebrand factor in peripheral blood
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    nature.com/articles/s41598-025-10321-6
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    Macrophage fatty acid metabolism under chronic hypoxia shapes γδ T cell recruitment via CCL22.
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    Engineering yeast multicellular behaviors via synthetic adhesion and contact signaling
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    KEAP1 and STK11/LKB1 alterations enhance vulnerability to ATR inhibition in KRAS mutant non-small cell lung cancer
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    Loss of NR2F6 Protects from Salmonella Typhimurium Infection
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    advanced.onlinelibrary.wiley.com/doi/10.1002/advs.202404280
  39. www.mdpi.com www.mdpi.com
    Subtherapeutic Dose of Ionizing Radiation Reprograms the Pre-Metastatic Lung Niche, Accelerating Its Formation and Promoting Metastasis
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    mdpi.com/1422-0067/26/13/6145
  40. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Uncovering novel lncRNAs linked to melanoma growth and migration with CRISPR-inhibition screening
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    pmc.ncbi.nlm.nih.gov/articles/PMC12238846/
  41. elifesciences.org elifesciences.org
    Unraveling CRP/cAMP-mediated metabolic regulation in Escherichia coli persister cells
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    elifesciences.org/articles/99735
  42. www.cell.com www.cell.com
    TET2-mutant myeloid cells mitigate Alzheimer’s disease progression via CNS infiltration and enhanced phagocytosis in mice
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  43. elifesciences.org elifesciences.org
    The ESCRT protein CHMP5 restricts bone formation by controlling endolysosome-mitochondrion-mediated cell senescence
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    elifesciences.org/articles/101984
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    HPV16-Expressing Tumors Release Multiple IL1 Ligands to Orchestrate Systemic Immunosuppression Whose Disruption Enables Efficacy of a Therapeutic Vaccine
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    pmc.ncbi.nlm.nih.gov/articles/PMC12223509/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Requirement for Cyclin D1 Underlies Cell-Autonomous HIF2 Dependence in Kidney Cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12223508/
  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RORγ Bridges Cancer-Driven Lipid Dysmetabolism and Myeloid Immunosuppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12223513/
  47. aacrjournals.org aacrjournals.org
    The DRD2 antagonist haloperidol mediates autophagy-induced ferroptosis to increase temozolomide sensitivity by promoting endoplasmic reticulum stress in glioblastoma
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    aacrjournals.org/clincancerres/article/29/16/3172/728242/The-DRD2-Antagonist-Haloperidol-Mediates-Autophagy
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    Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
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    52.53.155.43/baf73dc4816d69ae4de3fa32641dfd7bd010d8a5/Molecular and genetic evidence for the role of AMBRA1 in suppressing S-phase entry and tumorigenesis - ScienceDirect-html.html
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Effective TIL Therapy for Patients with Checkpoint-Resistant Melanoma without Lymphodepleting Regimens Requires IFNα
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    pmc.ncbi.nlm.nih.gov/articles/PMC12209825/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Clusterin facilitates glioma progression via BCL2L1-dependent regulation of apoptotic resistance
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  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multicenter study correlating molecular characteristics and clinical outcomes of cancer cases with patient-derived organoids
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    pmc.ncbi.nlm.nih.gov/articles/PMC12220348/
  52. www.ahajournals.org www.ahajournals.org
    Oxidized Phospholipid oxPAPC Alters Regulatory T-Cell Differentiation and Decreases Their Protective Function in Atherosclerosis in Mice
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    ahajournals.org/doi/10.1161/ATVBAHA.123.319674
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A Novel B7-H4xCD3 Bispecific T-cell Engager (PF-07260437) Synergizes with Breast Cancer Standard of Care and Immune Checkpoint Therapies
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  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tumor integrin-targeted glucose oxidase enzyme promotes ROS-mediated cell death that combines with interferon alpha therapy for tumor control
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    pmc.ncbi.nlm.nih.gov/articles/PMC11695183/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ammonia Suppresses the Antitumor Activity of Natural Killer Cells and T Cells by Decreasing Mature Perforin
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  56. link.springer.com link.springer.com
    Elucidating the role of N-myristoylation in the excessive membrane localization of PD-L1 in hypoxic cancers and developing a novel NMT1 inhibitor for combination with immune checkpoint blockade therapy
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    link.springer.com/article/10.1186/s13046-025-03438-z
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    The immune response against cancer is modulated by stromal cell fibronectin
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    sciencedirect.com/science/article/pii/S1476558625000764
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    Mitochondrial complex IV remodeling in tumor-associated macrophages amplifies interferon signaling and promotes anti-tumor immunity
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    Mutant p53 exploits enhancers to elevate immunosuppressive chemokine expression and impair immune checkpoint inhibitors in pancreatic cancer
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  60. Jun 2025
  61. www.sciencedirect.com www.sciencedirect.com
    Phenotypic screens for SIRPA expression reveal RAB21 as a general regulator of macrophage surface identity
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    VISTA immune checkpoint blunts radiotherapy-induced antitumor immune response
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    sciencedirect.com/science/article/pii/S2211124725006643
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    Prolonged but finite antigen presentation promotes reversible defects of “helpless” memory CD8+ T cells
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    sciencedirect.com/science/article/pii/S1074761325002468
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    NGN3 oscillatory expression controls the timing of human pancreatic endocrine differentiation
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    sciencedirect.com/science/article/pii/S1534580725003570
  65. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    PDZ-directed substrate recruitment is the primary determinant of specific 4E-BP1 dephosphorylation by PP1-Neurabin
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    pmc.ncbi.nlm.nih.gov/articles/PMC12185105/
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    EGFR TKIs suppress MUC1 glycosylation through the PI3K/AKT/SP1/C1GALT1 pathway to enhance TnMUC1 CAR-T efficacy in EGFR-mutant NSCLC
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    GPNMB marks a quiescent cell population in melanoma and promotes metastasis formation
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    Transcription factor T-bet regulates the maintenance and differentiation potential of lymph node and lung effector memory B cell subsets
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    CD18 and CD36 expression in neutrophils from tumors and tumor-draining lymph nodes: implications for metastasis in oral squamous cell carcinoma
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    link.springer.com/article/10.1007/s10585-025-10356-z
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    Cisplatin-Induced APE2 Overexpression Disrupts MYH9 Function and Causes Hearing Loss
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    pmc.ncbi.nlm.nih.gov/articles/PMC12179588/
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  73. journals.physiology.org journals.physiology.org
    Monocyte immunometabolic reprogramming in human pregnancy: contribution of trophoblast cells
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    journals.physiology.org/doi/full/10.1152/ajpendo.00357.2023
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    Monocyte immunometabolic reprogramming in human pregnancy: contribution of trophoblast cells
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    journals.physiology.org/doi/10.1152/ajpendo.00357.2023
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    PTEN neddylation aggravates CDK4/6 inhibitor resistance in breast cancer
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  77. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The dichotomous impacts of Semaphorin3E deficiency on exacerbating airway hyperresponsiveness, remodelling, and inflammation in type-2 low and type-2 high asthma models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12165363/
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    Myeloid Glutamine Synthetase Protects Against Acute Liver Injury in Mice Independent of Its Enzyme Activity
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    onlinelibrary.wiley.com/doi/10.1111/liv.70105
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    PRPS activity tunes redox homeostasis in Myc-driven lymphoma
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    Structural basis for the midnolin-proteasome pathway and its role in suppressing myeloma
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    Satb1 directs the differentiation of TH17 cells through suppression of IL-2 expression
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    Cancer-associated fibroblasts promote drug resistance in ALK-driven lung adenocarcinoma cells by upregulating lipid biosynthesis
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