336 Matching Annotations
  1. Mar 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Identification of new ETV6 modulators through a high throughput functional screening
    1
    1. scibot 02 Mar 2022
      RRID:SCR_016368

      DOI: 10.1016/j.isci.2022.103858

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    sciencedirect.com/science/article/pii/S2589004222001286
  3. Feb 2022
  4. www.sciencedirect.com www.sciencedirect.com
    Simultaneous cellular and molecular phenotyping of embryonic mutants using single-cell regulatory trajectories
    1
    1. scibot 18 Feb 2022
      RRID:SCR_016368

      DOI: 10.1016/j.devcel.2022.01.016

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    sciencedirect.com/science/article/pii/S1534580722000557
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    Uncovering the mesendoderm gene regulatory network through multi-omic data integration
    1
    1. scibot 16 Feb 2022
      RRID:SCR_016368

      DOI: 10.1016/j.celrep.2022.110364

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    sciencedirect.com/science/article/pii/S2211124722000857
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic analysis of naturally occurring insertions and deletions that alter transcription factor spacing identifies tolerant and sensitive transcription factor pairs
    1
    1. scibot 08 Feb 2022
      RRID:SCR_016368

      DOI: 10.7554/eLife.70878

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    ncbi.nlm.nih.gov/pmc/articles/PMC8809895/
  7. Jan 2022
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    Dynamic chromatin state profiling reveals regulatory roles of auxin and cytokinin in shoot regeneration
    1
    1. scibot 27 Jan 2022
      RRID:SCR_016368

      DOI: 10.1016/j.devcel.2021.12.019

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    sciencedirect.com/science/article/pii/S153458072101039X
  9. www.sciencedirect.com www.sciencedirect.com
    Multimodal regulatory elements within a hormone-specific super enhancer control a heterogeneous transcriptional response
    1
    1. scibot 26 Jan 2022
      RRID:SCR_016368

      DOI: 10.1016/j.molcel.2021.12.035

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    sciencedirect.com/science/article/pii/S1097276521011400
  10. www.sciencedirect.com www.sciencedirect.com
    Construction of Strand-seq libraries in open nanoliter arrays
    1
    1. scibot 26 Jan 2022
      RRID:SCR_016368

      DOI: 10.1016/j.crmeth.2021.100150

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    sciencedirect.com/science/article/pii/S2667237521002277
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heat shock factor 1 (HSF1) cooperates with estrogen receptor α (ERα) in the regulation of estrogen action in breast cancer cells
    1
    1. scibot 07 Jan 2022
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      DOI: 10.7554/eLife.69843

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    ncbi.nlm.nih.gov/pmc/articles/PMC8709578/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
    2
    1. scibot 05 Jan 2022
      RRID:SCR_016368

      DOI: 10.1158/1541-7786.MCR-20-0913

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    2. scibot 05 Jan 2022
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      DOI: 10.1158/1541-7786.MCR-20-0913

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    ncbi.nlm.nih.gov/pmc/articles/PMC8254790/
  13. Dec 2021
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
    1
    1. scibot 15 Dec 2021
      RRID:SCR_016368

      DOI: 10.7554/eLife.70992

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    ncbi.nlm.nih.gov/pmc/articles/PMC8664294/
  15. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
    1
    1. scibot 10 Dec 2021
      RRID:SCR_016368

      DOI: 10.1016/j.molcel.2021.11.016

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    cell.com/molecular-cell/fulltext/S1097-2765(21)00996-5
  16. www.sciencedirect.com www.sciencedirect.com
    Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis
    1
    1. scibot 08 Dec 2021
      RRID:SCR_016368

      DOI: 10.1016/j.celrep.2021.110099

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    sciencedirect.com/science/article/pii/S221112472101593X
  17. Nov 2021
  18. mcr.aacrjournals.org mcr.aacrjournals.org
    SOX9 Defines Distinct Populations of Cells in SHH Medulloblastoma but Is Not Required for Math1-Driven Tumor Formation
    1
    1. scibot 24 Nov 2021
      RRID:SCR_016368

      DOI: 10.1158/1541-7786.MCR-21-0117

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    mcr.aacrjournals.org/content/19/11/1831
  19. www.nature.com www.nature.com
    CHD5 inhibits metastasis of neuroblastoma
    1
    1. scibot 21 Nov 2021
      RRID:SCR_016368

      DOI: 10.1038/s41388-021-02081-0

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    nature.com/articles/s41388-021-02081-0
  20. www.sciencedirect.com www.sciencedirect.com
    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
    1
    1. scibot 12 Nov 2021
      RRID:SCR_016368

      DOI: 10.1016/j.molcel.2021.10.015

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    sciencedirect.com/science/article/pii/S1097276521009072
  21. www.sciencedirect.com www.sciencedirect.com
    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
    1
    1. scibot 10 Nov 2021
      RRID:SCR_016368

      DOI: 10.1016/j.celrep.2021.109921

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    sciencedirect.com/science/article/pii/S2211124721013942
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sequence features of retrotransposons allow for epigenetic variability
    1
    1. scibot 05 Nov 2021
      RRID:SCR_016368

      DOI: 10.7554/eLife.71104

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    ncbi.nlm.nih.gov/pmc/articles/PMC8555987/
  23. www.sciencedirect.com www.sciencedirect.com
    Kr-h1 maintains distinct caste-specific neurotranscriptomes in response to socially regulated hormones
    1
    1. scibot 05 Nov 2021
      RRID:SCR_016368

      DOI: 10.1016/j.cell.2021.10.006

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    sciencedirect.com/science/article/pii/S0092867421011806
  24. Oct 2021
  25. www.sciencedirect.com www.sciencedirect.com
    Conserved heterodimeric GTPase Rbg1/Tma46 promotes efficient translation in eukaryotic cells
    1
    1. scibot 27 Oct 2021
      RRID:SCR_016368

      DOI: 10.1016/j.celrep.2021.109877

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    sciencedirect.com/science/article/pii/S2211124721013474
  26. www.sciencedirect.com www.sciencedirect.com
    Induced intra- and intermolecular template switching as a therapeutic mechanism against RNA viruses
    1
    1. scibot 23 Oct 2021
      RRID:SCR_016368

      DOI: 10.1016/j.molcel.2021.10.003

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    sciencedirect.com/science/article/pii/S1097276521008327
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
    1
    1. scibot 20 Oct 2021
      RRID:SCR_016368

      DOI: 10.1158/0008-5472.CAN-21-1545

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    ncbi.nlm.nih.gov/pmc/articles/PMC8723353/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Clinical Significance of Circulating Tumor Cell Induced Epithelial-Mesenchymal Transition in Patients with Metastatic Colorectal Cancer by Single-Cell RNA-Sequencing
    1
    1. scibot 15 Oct 2021
      RRID:SCR_016368

      DOI: 10.3390/cancers13194862

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    ncbi.nlm.nih.gov/pmc/articles/PMC8507666/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A chromosome-level genome assembly for the eastern fence lizard (Sceloporus undulatus), a reptile model for physiological and evolutionary ecology
    1
    1. scibot 06 Oct 2021
      RRID:SCR_016368

      DOI: 10.1093/gigascience/giab066

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    ncbi.nlm.nih.gov/pmc/articles/PMC8486681/
  30. www.sciencedirect.com www.sciencedirect.com
    Acrylamide modulates the mouse epididymal proteome to drive alterations in the sperm small non-coding RNA profile and dysregulate embryo development
    1
    1. scibot 06 Oct 2021
      RRID:SCR_016368

      DOI: 10.1016/j.celrep.2021.109787

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    sciencedirect.com/science/article/pii/S2211124721012468
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
    1
    1. scibot 05 Oct 2021
      RRID:SCR_016368

      DOI: 10.1126/sciadv.abj3035

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    ncbi.nlm.nih.gov/pmc/articles/PMC8462898/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tiled-ClickSeq for targeted sequencing of complete coronavirus genomes with simultaneous capture of RNA recombination and minority variants
    1
    1. scibot 02 Oct 2021
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      DOI: 10.7554/eLife.68479

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    ncbi.nlm.nih.gov/pmc/articles/PMC8478411/
  33. Sep 2021
  34. www.science.org www.science.org
    Global chromatin relabeling accompanies spatial inversion of chromatin in rod photoreceptors
    1
    1. scibot 29 Sep 2021
      RRID:SCR_016368

      DOI: 10.1126/sciadv.abj3035

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    science.org/doi/abs/10.1126/sciadv.abj3035
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocytic differentiation and AHR signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
    1
    1. scibot 28 Sep 2021
      RRID:SCR_016368

      DOI: 10.1158/2643-3230.bcd-21-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC8462123/
  36. www.sciencedirect.com www.sciencedirect.com
    H3K4 di-methylation governs smooth muscle lineage identity and promotes vascular homeostasis by restraining plasticity
    1
    1. scibot 28 Sep 2021
      RRID:SCR_016368

      DOI: 10.1016/j.devcel.2021.09.001

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    sciencedirect.com/science/article/pii/S1534580721006821
  37. www.sciencedirect.com www.sciencedirect.com
    SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling
    1
    1. scibot 28 Sep 2021
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      DOI: 10.1016/j.stem.2021.09.004

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    sciencedirect.com/science/article/pii/S1934590921003805
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging the Mendelian disorders of the epigenetic machinery to systematically map functional epigenetic variation
    1
    1. scibot 22 Sep 2021
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      DOI: 10.7554/eLife.65884

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    ncbi.nlm.nih.gov/pmc/articles/PMC8443249/
  39. www.sciencedirect.com www.sciencedirect.com
    Proteopathic tau primes and activates interleukin-1β via myeloid-cell-specific MyD88- and NLRP3-ASC-inflammasome pathway
    1
    1. scibot 22 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109720

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    sciencedirect.com/science/article/pii/S2211124721011694
  40. www.sciencedirect.com www.sciencedirect.com
    SPT5 stabilizes RNA polymerase II, orchestrates transcription cycles, and maintains the enhancer landscape
    1
    1. scibot 17 Sep 2021
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      DOI: 10.1016/j.molcel.2021.08.029

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    sciencedirect.com/science/article/pii/S1097276521006961
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism
    1
    1. scibot 14 Sep 2021
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      DOI: 10.7554/eLife.65574

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    ncbi.nlm.nih.gov/pmc/articles/PMC8410083/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
    1
    1. scibot 11 Sep 2021
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      DOI: 10.7554/eLife.69142

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    ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
  43. www.sciencedirect.com www.sciencedirect.com
    Transcriptional control of brain tumor stem cells by a carbohydrate binding protein
    1
    1. scibot 01 Sep 2021
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      DOI: 10.1016/j.celrep.2021.109647

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    sciencedirect.com/science/article/pii/S2211124721010901
  44. Aug 2021
  45. www.sciencedirect.com www.sciencedirect.com
    Conditional stomatal closure in a fern shares molecular features with flowering plant active stomatal responses
    1
    1. scibot 27 Aug 2021
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      DOI: 10.1016/j.cub.2021.08.008

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    sciencedirect.com/science/article/pii/S0960982221011106
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cis-regulatory variants affect gene expression dynamics in yeast
    1
    1. scibot 21 Aug 2021
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      DOI: 10.7554/eLife.68469

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    ncbi.nlm.nih.gov/pmc/articles/PMC8367379/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1
    1
    1. scibot 21 Aug 2021
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      DOI: 10.7554/eLife.64846

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    ncbi.nlm.nih.gov/pmc/articles/PMC8370767/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heterochromatin-dependent transcription of satellite DNAs in the Drosophila melanogaster female germline
    1
    1. scibot 15 Aug 2021
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      DOI: 10.7554/eLife.62375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8321551/
  49. www.sciencedirect.com www.sciencedirect.com
    CLOCKWORK ORANGE promotes CLOCK-CYCLE activation via the putative Drosophila ortholog of CLOCK INTERACTING PROTEIN CIRCADIAN
    1
    1. scibot 15 Aug 2021
      RRID:SCR_016368

      DOI: 10.1016/j.cub.2021.07.017

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    sciencedirect.com/science/article/pii/S0960982221009726
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      DOI: 10.1093/gigascience/giy168

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      DOI: 10.1016/j.celrep.2019.01.091

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      DOI: 10.7554/eLife.40197

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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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      DOI: 10.7554/eLife.42426

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    De Novo PITX1 Expression Controls Bi-Stable Transcriptional Circuits to Govern Self-Renewal and Differentiation in Squamous Cell Carcinoma
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      RRID:SCR_016368

      DOI: 10.1016/j.stem.2019.01.003

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      DOI: 10.7554/eLife.39380

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      RRID:SCR_016368

      DOI: 10.1016/j.molcel.2018.11.006

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    Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans
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      RRID:SCR_016368

      DOI: 10.1016/j.devcel.2019.01.019

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  111. Nov 2018
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    The SS18-SSX Oncoprotein Hijacks KDM2B-PRC1.1 to Drive Synovial Sarcoma
    1
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      Bowtie2

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    LKB1, Salt-Inducible Kinases, and MEF2C Are Linked Dependencies in Acute Myeloid Leukemia
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    Fas Promotes T Helper 17 Cell Differentiation and Inhibits T Helper 1 Cell Development by Binding and Sequestering Transcription Factor STAT1
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    1. scibot 05 Nov 2018
      Bowtie

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    Developmental History Provides a Roadmap for the Emergence of Tumor Plasticity
    1
    1. scibot 05 Nov 2018
      Bowtie

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    sciencedirect.com/science/article/pii/S1534580718301564
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    Polymer Simulations of Heteromorphic Chromatin Predict the 3D Folding of Complex Genomic Loci
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      Bowtie2

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    RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss
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      SCR_016368

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    sciencedirect.com/science/article/pii/S2211124718315377
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stage-Specific Transcription Factors Drive Astrogliogenesis by Remodeling Gene Regulatory Landscapes
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC6179960/
  120. www.sciencedirect.com www.sciencedirect.com
    A Short Tandem Repeat-Enriched RNA Assembles a Nuclear Compartment to Control Alternative Splicing and Promote Cell Survival
    1
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      Bowtie2

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    sciencedirect.com/science/article/pii/S1097276518307019
  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TFAP2 transcription factors are regulators of lipid droplet biogenesis
    1
    1. scibot 05 Nov 2018
      bowtie2

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    ncbi.nlm.nih.gov/pmc/articles/PMC6170152/
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    Decoding Transcriptome Dynamics of Genome-Encoded Polyadenylation and Autoregulation with Small-Molecule Modulators of Alternative Polyadenylation
    1
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      Bowtie2

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    sciencedirect.com/science/article/pii/S2451945618303015
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    Elongation/Termination Factor Exchange Mediated by PP1 Phosphatase Orchestrates Transcription Termination
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    sciencedirect.com/science/article/pii/S2211124718314220
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    HOXA9 Reprograms the Enhancer Landscape to Promote Leukemogenesis
    1
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      Bowtie2

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    sciencedirect.com/science/article/pii/S1535610818303787
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    Prospective Isolation and Characterization of Genetically and Functionally Distinct AML Subclones
    1
    1. scibot 05 Nov 2018
      Bowtie

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    Examining the Roles of H3K4 Methylation States with Systematically Characterized Antibodies
    1
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      Bowtie2

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    The Mcm2-Ctf4-Polα Axis Facilitates Parental Histone H3-H4 Transfer to Lagging Strands
    1
    1. scibot 05 Nov 2018
      Bowtie2

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  129. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing
    1
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      Bowtie2

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    ncbi.nlm.nih.gov/pmc/articles/PMC6108849/
  130. www.sciencedirect.com www.sciencedirect.com
    Phosphorylation of the Ribosomal Protein RPL12/uL11 Affects Translation during Mitosis
    1
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      Bowtie 2

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    Dietary Lipids Modulate Notch Signaling and Influence Adult Intestinal Development and Metabolism in Drosophila
    1
    1. scibot 05 Nov 2018
      Bowtie

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    Single Cell and Open Chromatin Analysis Reveals Molecular Origin of Epidermal Cells of the Skin
    1
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      Bowtie2

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    A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    Aberrant ERBB4-SRC Signaling as a Hallmark of Group 4 Medulloblastoma Revealed by Integrative Phosphoproteomic Profiling
    1
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      Bowtie 2

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    sciencedirect.com/science/article/pii/S1535610818303568
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    Mutant NPM1 Maintains the Leukemic State through HOX Expression
    1
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      Bowtie2

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    MEF2B Instructs Germinal Center Development and Acts as an Oncogene in B Cell Lymphomagenesis
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS
    1
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      Bowtie2

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    sciencedirect.com/science/article/pii/S1535610818303696
  138. www.sciencedirect.com www.sciencedirect.com
    Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    sciencedirect.com/science/article/pii/S1934590918303862
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    The Evf2 Ultraconserved Enhancer lncRNA Functionally and Spatially Organizes Megabase Distant Genes in the Developing Forebrain
    1
    1. scibot 05 Nov 2018
      bowtie2

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    sciencedirect.com/science/article/pii/S1097276518305938
  140. www.sciencedirect.com www.sciencedirect.com
    Transcription Elongation Can Affect Genome 3D Structure
    1
    1. scibot 05 Nov 2018
      Bowtie2

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    sciencedirect.com/science/article/pii/S0092867418309759
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    Dismissal of RNA Polymerase II Underlies a Large Ligand-Induced Enhancer Decommissioning Program
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    1. scibot 05 Nov 2018
      RRID:SCR_016368

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    sciencedirect.com/science/article/pii/S1097276518306324
  142. www.sciencedirect.com www.sciencedirect.com
    Neutralizing Gatad2a-Chd4-Mbd3/NuRD Complex Facilitates Deterministic Induction of Naive Pluripotency
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    1. scibot 05 Nov 2018
      Bowtie 2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1934590918303400
  143. www.sciencedirect.com www.sciencedirect.com
    GATA/Heme Multi-omics Reveals a Trace Metal-Dependent Cellular Differentiation Mechanism
    1
    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @Jmenke

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      (Bowtie 2, RRID:SCR_016368)

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    sciencedirect.com/science/article/pii/S1534580718306075
  144. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 05 Nov 2018
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    sciencedirect.com/science/article/pii/S0092867418308559
  145. www.sciencedirect.com www.sciencedirect.com
    Decoupling Yeast Cell Division and Stress Defense Implicates mRNA Repression in Translational Reallocation during Stress
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    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S0960982218308352
  146. www.sciencedirect.com www.sciencedirect.com
    Dual Roles of Poly(dA:dT) Tracts in Replication Initiation and Fork Collapse
    1
    1. scibot 05 Nov 2018
      Bowtie 2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S009286741830905X
  147. www.sciencedirect.com www.sciencedirect.com
    Cicero Predicts cis-Regulatory DNA Interactions from Single-Cell Chromatin Accessibility Data
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    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518305471
  148. www.sciencedirect.com www.sciencedirect.com
    Genome-wide Map of R-Loop-Induced Damage Reveals How a Subset of R-Loops Contributes to Genomic Instability
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    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S1097276518305124
  149. www.sciencedirect.com www.sciencedirect.com
    Loss of H3K27me3 Imprinting in Somatic Cell Nuclear Transfer Embryos Disrupts Post-Implantation Development
    1
    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @Jmenke

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    sciencedirect.com/science/article/pii/S193459091830290X
  150. www.sciencedirect.com www.sciencedirect.com
    A Quick HYL1-Dependent Reactivation of MicroRNA Production Is Required for a Proper Developmental Response after Extended Periods of Light Deprivation
    1
    1. scibot 05 Nov 2018
      Bowtie2

      Curator: @anp055

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      (Bowtie 2, RRID:SCR_016368)

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    sciencedirect.com/science/article/pii/S1534580718304994