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  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    The chromosome-level genome assembly of an endangered herb Bergenia scopulosa provides insights into local adaptation and genomic vulnerability under climate change
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      DOI: 10.1093/gigascience/giae091

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  3. Dec 2024
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    H4K20me3-Mediated Repression of Inflammatory Genes is a Characteristic and Targetable Vulnerability of Persister Cancer Cells
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    1. scibot 13 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC7617193/
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    The telomere-to-telomere (T2T) genome provides insights into the evolution of specialized centromere sequences in sandalwood
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    1. scibot 13 Dec 2024
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    Functional annotation of regulatory elements in rainbow trout uncovers roles of the epigenome in genetic selection and genome evolution
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    1. scibot 13 Dec 2024
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    Epigenetic and Oncogenic Inhibitors Cooperatively Drive Differentiation and Kill KRAS-Mutant Colorectal Cancers
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    Single chromatin fiber profiling and nucleosome position mapping in the human brain
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    sciencedirect.com/science/article/pii/S2667237524003011
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    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    1. scibot 05 Dec 2024
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    sciencedirect.com/science/article/pii/S1097276524009146
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    The phosphatase PP1 sustains global transcription by promoting RNA polymerase II pause release
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    sciencedirect.com/science/article/pii/S1097276524008852
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    Evolutionary genomics of the emergence of brown algae as key components of coastal ecosystems
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    sciencedirect.com/science/article/pii/S0092867424012728
  12. Nov 2024
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    Harnessing biosynthesized selenium nanoparticles for recruitment of beneficial soil microbes to plant roots
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    sciencedirect.com/science/article/pii/S1931312824004013
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    ISWI chromatin remodeling complexes recruit NSD2 and H3K36me2 in pericentromeric heterochromatin
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    1. scibot 08 Nov 2024
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      DOI: 10.1083/jcb.202310084

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    New Small-Molecule SERCA Inhibitors Enhance Treatment Efficacy in Lenvatinib-Resistant Papillary Thyroid Cancer
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    1. scibot 07 Nov 2024
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      DOI: 10.3390/ijms251910646

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    1. scibot 07 Nov 2024
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  17. Oct 2024
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    HOXDeRNA activates a cancerous transcription program and super enhancers via genome-wide binding
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    1. scibot 09 Oct 2024
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    RiboSnake – a user-friendly, robust, reproducible, multipurpose and documentation-extensive pipeline for 16S rRNA gene microbiome analysis
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    1. scibot 06 Oct 2024
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      DOI: 10.46471/gigabyte.132

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    V-pipe 3.0: a sustainable pipeline for within-sample viral genetic diversity estimation
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    1. scibot 02 Oct 2024
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    Monocytic Differentiation and AHR Signaling as Primary Nodes of BET Inhibitor Response in Acute Myeloid Leukemia
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      DOI: 10.1158/2643-3230.BCD-21-0012

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    aacrjournals.org/bloodcancerdiscov/article/2/5/518/665838/Monocytic-Differentiation-and-AHR-Signaling-as
  22. Sep 2024
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    Tracing early pastoralism in Central Europe using sedimentary ancient DNA
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    Divergent iron regulatory states contribute to heterogeneity in breast cancer aggressiveness
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    Multiple direct and indirect roles of the Paf1 complex in transcription elongation, splicing, and histone modifications
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    1. scibot 10 Sep 2024
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    Targeting EGLN2/PHD1 protects motor neurons and normalizes the astrocytic interferon response
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    1. scibot 10 Sep 2024
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    Streamlined regulation of chloroplast development in the liverwort Marchantia polymorpha
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  28. Aug 2024
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterizing Relationships between T-cell Inflammation and Outcomes in Patients with High-Risk Neuroblastoma According to Mesenchymal and Adrenergic Signatures
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    1. scibot 30 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0214

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    Acral fibrochondromyxoid tumor: a clinicopathologic and molecular genetic study of 37 cases
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      DOI: 10.1016/j.modpat.2024.100599

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    sciencedirect.com/science/article/pii/S0893395224001790
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    CRISPR screening uncovers a long-range enhancer for ONECUT1 in pancreatic differentiation and links a diabetes risk variant
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    Members of an array of zinc-finger proteins specify distinct Hox chromatin boundaries
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    HLTF resolves G4s and promotes G4-induced replication fork slowing to maintain genome stability
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  34. www.biorxiv.org www.biorxiv.org
    The multi-level effect of chlorpyrifos during clownfish metamorphosis
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      DOI: 10.1101/2024.08.02.606305

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    MOBFinder: a tool for mobilization typing of plasmid metagenomic fragments based on a language model
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      DOI: 10.1093/gigascience/giae047

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    A replisome-associated histone H3-H4 chaperone required for epigenetic inheritance
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    Heteromeric RNP Assembly at LINEs Controls Lineage-Specific RNA Processing
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  38. Jul 2024
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ZNF397 Deficiency Triggers TET2-Driven Lineage Plasticity and AR-Targeted Therapy Resistance in Prostate Cancer
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  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Epigenetic Induction of Cancer-Testis Antigens and Endogenous Retroviruses at Single-Cell Level Enhances Immune Recognition and Response in Glioma
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    Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection
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      DOI: 10.1016/j.isci.2024.110525

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    A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes
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      DOI: 10.1099/acmi.0.000639.v3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11261729/
  43. www.cell.com www.cell.com
    Innate immune training restores pro-reparative myeloid functions to promote remyelination in the aged central nervous system
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      DOI: 10.1016/j.immuni.2024.07.001

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    cell.com/immunity/fulltext/S1074-7613(24)00348-0
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    MYB-related transcription factors control chloroplast biogenesis
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      DOI: 10.1016/j.cell.2024.06.039

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A ghost moth olfactory prototype of the lepidopteran sex communication
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      DOI: 10.1093/gigascience/giae044

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    ncbi.nlm.nih.gov/pmc/articles/PMC11258902/
  46. www.science.org www.science.org
    The annotation of GBA1 has been concealed by its protein-coding pseudogene GBAP1
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      DOI: 10.1126/sciadv.adk1296

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    science.org/doi/10.1126/sciadv.adk1296
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Netrin signaling mediates survival of dormant epithelial ovarian cancer cells
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    1. scibot 20 Jul 2024
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      DOI: 10.7554/eLife.91766

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    ncbi.nlm.nih.gov/pmc/articles/PMC11257678/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ALDH1A3-acetaldehyde metabolism potentiates transcriptional heterogeneity in melanoma
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    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
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    CD8+ T cell memory induced by successive SARS-CoV-2 mRNA vaccinations is characterized by shifts in clonal dominance
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    The transcription factor NF-κB orchestrates nucleosome remodeling during the primary response to Toll-like receptor 4 signaling
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    Treatment response in first-line metastatic pancreatic ductal adenocarcinoma is stratified by a composite index of tumor proliferation and CD8 T cell infiltration
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  98. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
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    SLAM-ITseq identifies that Nrf2 induces liver regeneration through the pentose phosphate pathway
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    The androgen receptor interacts with GATA3 to transcriptionally regulate a luminal epithelial cell phenotype in breast cancer
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    Targeting N-linked Glycosylation for the Therapy of Aggressive Lymphomas
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    Development of sexual dimorphism of skeletal muscles through the adrenal cortex, caused by androgen-induced global gene suppression
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    5-Hydroxymethylcytosine signals in serum are a predictor of chemoresistance in high-grade serous ovarian cancer
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    PRDM3/16 Regulate Chromatin Accessibility Required for NKX2-1 Mediated Alveolar Epithelial Differentiation and Function
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    Early microbial intervention reshapes phenotypes of newborn Bos taurus through metabolic regulations
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    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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    Mitochondrial isocitrate dehydrogenase impedes CAR T cell function by restraining antioxidant metabolism and histone acetylation
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    Pluripotency state transition of embryonic stem cells requires the turnover of histone chaperone FACT on chromatin
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    Characterization of nucleolar SUMO isopeptidases unveils a general p53-independent checkpoint of impaired ribosome biogenesis
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    Genetic swamping of the critically endangered Scottish wildcat was recent and accelerated by disease
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    Genome organization regulates nuclear pore complex formation and promotes differentiation during Drosophila oogenesis
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    A nuclear architecture screen in Drosophila identifies Stonewall as a link between chromatin position at the nuclear periphery and germline stem cell fate
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  122. Nov 2023
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    Genomic and transcriptomic characterization of delta SARS-CoV-2 infection in free-ranging white-tailed deer (Odocoileus virginianus)
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    Repression of LSD1 potentiates homologous recombination-proficient ovarian cancer to PARP inhibitors through down-regulation of BRCA1/2 and RAD51
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    LINE-1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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    Broodstock nutritional programming differentially affects the hepatic transcriptome and genome-wide DNA methylome of farmed gilthead sea bream (Sparus aurata) depending on genetic background
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    Oral vancomycin treatment suppresses gut trypsin activity and preserves intestinal barrier function during EAE
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    Zinc Finger MYND-Type Containing 8 (ZMYND8) is epigenetically regulated in mutant Isocitrate Dehydrogenase 1 (IDH1) glioma to promote radioresistance
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    Tissue-specific and tissue-agnostic effects of genome sequence variation modulating blood pressure
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    ZNF397 Loss Triggers TET2-driven Epigenetic Rewiring, Lineage Plasticity, and AR-targeted Therapy Resistance in AR-dependent Cancers
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  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular and functional characterization of the Drosophila melanogaster conserved smORFome
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    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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    Three-dimensional genome architecture coordinates key regulators of lineage specification in mammary epithelial cells
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic context shapes the fitness landscape of tumor suppression
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  138. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    nf-core/clipseq - a robust Nextflow pipeline for comprehensive CLIP data analysis
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  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A single-cell multi-omic atlas spanning the adult rhesus macaque brain
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  140. dx.doi.org dx.doi.org
    Chromatin accessibility landscape of human triple-negative breast cancer cell lines reveals variation by patient donor ancestry
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  141. www.nature.com www.nature.com
    TET2 lesions enhance the aggressiveness of CEBPA-mutant acute myeloid leukemia by rebalancing GATA2 expression
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of Neural Fate by Combination of BMP Blockade and Chromatin Modification
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromosome-level reference genome of tetraploid Isoetes sinensis provides insights into evolution and adaption of lycophytes
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  144. Sep 2023
  145. 52.53.155.43 52.53.155.43
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  146. dx.doi.org dx.doi.org
    Targeting KDM2A Enhances T Cell Infiltration in NSD1-Deficient Head and Neck Squamous Cell Carcinoma
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  147. Aug 2023
  148. www.biorxiv.org www.biorxiv.org
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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  149. 52.53.155.43 52.53.155.43
    Aberrant accumulation of Kras-dependent pervasive transcripts during tumor progression renders cancer cells dependent on PAF1 expression
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  150. 52.53.155.43 52.53.155.43
    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Proteasome Inhibition Sensitizes Liposarcoma to MDM2 Inhibition with Nutlin-3 by Activating the ATF4/CHOP Stress Response Pathway
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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deficiency of the Polycomb protein RYBP and TET methylcytosine oxidases promotes extensive CpG island hypermethylation and malignant transformation
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Longitudinal map of transcriptome changes in the Lyme pathogen Borrelia burgdorferi during tick-borne transmission
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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone variants shape chromatin states in Arabidopsis
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  155. Jul 2023
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pharmacological HDAC inhibition impairs pancreatic β-cell function through an epigenome-wide reprogramming
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  157. www.sciencedirect.com www.sciencedirect.com
    Parallel CRISPR-Cas9 screens identify mechanisms of PLIN2 and lipid droplet regulation
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    Evolutionary history of Staphylococcus aureus influences antibiotic resistance evolution
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    Bacterial clade-specific analysis identifies distinct epithelial responses in inflammatory bowel disease
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    A clinical metagenomic study of biopsies from Mexican endophthalmitis patients reveals the presence of complex bacterial communities and a diversity of resistance genes
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  161. www.sciencedirect.com www.sciencedirect.com
    Co-targeting RANK pathway treats and prevents acquired resistance to CDK4/6 inhibitors in luminal breast cancer
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An initial genomic blueprint of the healthy human oesophageal microbiome
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  163. 52.53.155.43 52.53.155.43
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  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome assembly of the hybrid grapevine Vitis ‘Chambourcin’
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  166. Jun 2023
  167. 52.53.155.43 52.53.155.43
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  169. www.embopress.org www.embopress.org
    DOT1L bridges transcription and heterochromatin formation at mammalian pericentromeres
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  170. 52.53.155.43 52.53.155.43
    Modelling host-Trypanosoma brucei gambiense interactions in vitro using human induced pluripotent stem cell-derived cortical brain organoids
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  171. aacrjournals.org aacrjournals.org
    (R)-2-hydroxyglutarate inhibits KDM5 histone lysine demethylases to drive transformation in IDH-mutant cancers
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  172. May 2023
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comparative analysis of microRNA expression profiles in shoot and root tissues of contrasting rice cultivars (Oryza sativa L.) with different salt stress tolerance
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  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Developmental dynamics of chromatin accessibility during post-implantation development of monkey embryos
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  175. 52.53.155.43 52.53.155.43
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  176. www.sciencedirect.com www.sciencedirect.com
    Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases
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  177. onlinelibrary.wiley.com onlinelibrary.wiley.com
    KMT2D Deficiency Promotes Myeloid Leukemias which Is Vulnerable to Ribosome Biogenesis Inhibition
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  178. www.biorxiv.org www.biorxiv.org
    L1 retrotransposons drive human neuronal transcriptome complexity and functional diversification
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  179. Apr 2023
  180. www.sciencedirect.com www.sciencedirect.com
    A hyper-quiescent chromatin state formed during aging is reversed by regeneration
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      DOI: 10.1016/j.molcel.2023.04.005

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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Novel enhancers conferring compensatory transcriptional regulation of Nkx2-5 in heart development
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    INTAC endonuclease and phosphatase modules differentially regulate transcription by RNA polymerase II
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    Complementary gene regulation by NRF1 and NRF2 protects against hepatic cholesterol overload
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    Asparagine starvation suppresses histone demethylation through iron depletion
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    Histone phosphorylation integrates the hepatic glucagon-PKA-CREB gluconeogenesis program in response to fasting
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    Atria: an ultra-fast and accurate trimmer for adapter and quality trimming
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    Genome assembly of the roundjaw bonefish (Albula glossodonta), a vulnerable circumtropical sportfish
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    Stepwise activities of mSWI/SNF family chromatin remodeling complexes direct T cell activation and exhaustion
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    SnakeMAGs: a simple, efficient, flexible and scalable workflow to reconstruct prokaryotic genomes from metagenomes
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    Hippo pathway and Bonus control developmental cell fate decisions in the Drosophila eye
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    A chromosome-scale draft genome sequence of horsegram (Macrotyloma uniflorum)
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    Human hematopoietic stem cell vulnerability to ferroptosis
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    The BRD4 inhibitor JQ1 augments the antitumor efficacy of abemaciclib in preclinical models of gastric carcinoma
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    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
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    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
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    Genomic view of the diversity and functional role of archaea and bacteria in the skeleton of the reef-building corals Porites lutea and Isopora palifera
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    Cancer stem cells, not bulk tumor cells, determine mechanisms of resistance to SMO inhibitors
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    A chromosome-scale assembly for tetraploid sour cherry (Prunus cerasus L.) ‘Montmorency’ identifies three distinct ancestral Prunus genomes
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    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
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    Resistance to white spot syndrome virus in the European shore crab is associated with suppressed virion trafficking and heightened immune responses
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    PRC2 Inactivating Mutations in Cancer Enhance Cytotoxic Response to DNMT1 Targeted Therapy via Enhanced Viral Mimicry
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    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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    BAF complex maintains glioma stem cells in pediatric H3K27M-glioma
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    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    Transcriptomic Correlates of Tumor Cell PD-L1 Expression and Response to Nivolumab Monotherapy in Metastatic Clear Cell Renal Cell Carcinoma
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    Essential role of MESP1-RING1A complex in cardiac differentiation
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    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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    High-quality genome assembles from key Hawaiian coral species
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    Transcription factor antagonism regulates heterogeneity in embryonic stem cell states
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