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  1. Dec 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A PDE10A inhibitor CPL500036 is a novel agent modulating striatal function devoid of most neuroleptic side-effects
    1
    1. scibot 02 Dec 2022
      RRID:SCR_002798

      DOI: 10.3389/fphar.2022.999685

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681820/
  3. 52.53.155.43 52.53.155.43
    JNEUROSCI.1630-22.2022.full-html.html
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    1. scibot 01 Dec 2022
      SCR_002798

      DOI: 10.1523/jneurosci.1630-22.2022

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    52.53.155.43/118bb3ecef5e9bd9dd2ed70db05de8737fb54852/JNEUROSCI.1630-22.2022.full-html.html
  4. 52.53.155.43 52.53.155.43
    Physcion alleviates chronic alcoholic hepatic inflammation and pyroptosis through SIRT1-AMPK activation
    1
    1. scibot 01 Dec 2022
      SCR_002798

      DOI: 10.22541/au.166257909.92233724/v1

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    52.53.155.43/f3d17e10a18ac12c4d6d977dcc236d4343a64cd5/585150-html.html
  5. 52.53.155.43 52.53.155.43
    The amygdala-ventral pallidum pathway contributes to a hypodopaminergic state in the ventral tegmental area during protracted abstinence from chronic cocaine
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    1. scibot 01 Dec 2022
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      DOI: 10.22541/au.166266560.09303461/v1

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    52.53.155.43/0b93e0d74fac46d4a91fe3dca92e8eb23ce1bd09/585313-html.html
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    Deficits in Cerebellum-Dependent Learning and Cerebellar Morphology in Male and Female BTBR Autism Model Mice
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    1. scibot 01 Dec 2022
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      DOI: 10.3390/neurosci3040045

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    mdpi.com/2673-4087/3/4/45
  7. 52.53.155.43 52.53.155.43
    ccr-22-1382-html.html
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    1. scibot 01 Dec 2022
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      DOI: 10.1158/1078-0432.ccr-22-1382

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    Chemical and mechanical activation of resident cardiac macrophages in the living myocardial slice ex vivo model
    1
    1. scibot 01 Dec 2022
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      DOI: 10.1007/s00395-022-00971-2

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    link.springer.com/article/10.1007/s00395-022-00971-2
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ascaris suum excretory/secretory products differentially modulate porcine dendritic cell subsets
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    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.3389/fimmu.2022.1012717

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    ncbi.nlm.nih.gov/pmc/articles/PMC9691337/
  10. 52.53.155.43 52.53.155.43
    can-22-1744-html.html
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    1. scibot 01 Dec 2022
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      DOI: 10.1158/0008-5472.can-22-1744

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  11. 52.53.155.43 52.53.155.43
    can-22-0455-html.html
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    1. scibot 01 Dec 2022
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      DOI: 10.1158/0008-5472.CAN-22-0455

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  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cross-reactive SARS-CoV-2 epitope targeted across donors informs immunogen design
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    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.1016/j.xcrm.2022.100834

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    ncbi.nlm.nih.gov/pmc/articles/PMC9663748/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytoprotective Properties of a New Nanocomplex of Selenium with Taxifolin in the Cells of the Cerebral Cortex Exposed to Ischemia/Reoxygenation
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    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.3390/pharmaceutics14112477

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    ncbi.nlm.nih.gov/pmc/articles/PMC9697510/
  14. www.sciencedirect.com www.sciencedirect.com
    Inhibition of Rho-kinase ameliorates decreased spine density in the medial prefrontal cortex and methamphetamine-induced cognitive dysfunction in mice carrying schizophrenia-associated mutations of the Arhgap10 gene.
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    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.1016/j.phrs.2022.106589

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    sciencedirect.com/science/article/pii/S1043661822005357
  15. www.eneuro.org www.eneuro.org
    The developmental progression of eight opsin spectral signals recorded from the zebrafish retinal cone layer is altered by the timing and cell type expression of thyroxin receptor β2 (trβ2) gain-of-function transgenes
    1
    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.1523/ENEURO.0326-22.2022

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    eneuro.org/content/9/6/ENEURO.0326-22.2022
  16. www.sciencedirect.com www.sciencedirect.com
    Madm/NRBP1 mediates synaptic maintenance and neurodegeneration-induced presynaptic homeostatic potentiation
    1
    1. scibot 01 Dec 2022
      RRID:SCR_002798

      DOI: 10.1016/j.celrep.2022.111710

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    sciencedirect.com/science/article/pii/S2211124722015844
  17. Nov 2022
  18. www.nature.com www.nature.com
    Tautomycin and enzalutamide combination yields synergistic effects on castration-resistant prostate cancer
    1
    1. scibot 30 Nov 2022
      RRID:SCR_002798

      DOI: 10.1038/s41420-022-01257-1

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    nature.com/articles/s41420-022-01257-1
  19. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Terminal field volume of the glossopharyngeal nerve in adult rats reverts to prepruning size following microglia depletion with PLX5622
    1
    1. scibot 30 Nov 2022
      RRID:SCR_002798

      DOI: 10.1002/dneu.22904

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    onlinelibrary.wiley.com/doi/10.1002/dneu.22904
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic Ca2+ imaging of cortical neurons with long-term expression of GCaMP-X
    1
    1. scibot 30 Nov 2022
      RRID:SCR_002798

      DOI: 10.7554/eLife.76691

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    ncbi.nlm.nih.gov/pmc/articles/PMC9699699/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    R-spondin 3 deletion induces Erk phosphorylation to enhance Wnt signaling and promote bone formation in the appendicular skeleton
    1
    1. scibot 30 Nov 2022
      RRID:SCR_002798

      DOI: 10.7554/eLife.84171

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    ncbi.nlm.nih.gov/pmc/articles/PMC9681208/
  22. link.springer.com link.springer.com
    The Effects of Cuprizone on Murine Subventricular Zone-Derived Neural Stem Cells and Progenitor Cells Grown as Neurospheres
    1
    1. scibot 29 Nov 2022
      RRID:SCR_002798

      DOI: 10.1007/s12035-022-03096-8

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    link.springer.com/article/10.1007/s12035-022-03096-8
  23. www.sciencedirect.com www.sciencedirect.com
    Unaltered T cell responses to common antigens in individuals with Parkinson's disease
    1
    1. scibot 29 Nov 2022
      RRID:SCR_002798

      DOI: 10.1016/j.jns.2022.120510

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    sciencedirect.com/science/article/pii/S0022510X22003720
  24. www.nature.com www.nature.com
    Protein aggregation and calcium dysregulation are hallmarks of familial Parkinson’s disease in midbrain dopaminergic neurons
    1
    1. scibot 29 Nov 2022
      RRID:SCR_002798

      DOI: 10.1038/s41531-022-00423-7

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    nature.com/articles/s41531-022-00423-7
  25. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Integration of the CA2 region in the hippocampal network during epileptogenesis
    1
    1. scibot 29 Nov 2022
      RRID:SCR_002798

      DOI: 10.1002/hipo.23479

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    onlinelibrary.wiley.com/doi/10.1002/hipo.23479
  26. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
    1
    1. scibot 24 Nov 2022
      RRID:SCR_002798

      DOI: 10.1016/j.molcel.2022.11.002

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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  27. www.sciencedirect.com www.sciencedirect.com
    A tick C1q protein alters infectivity of the Lyme disease agent by modulating interferon γ
    1
    1. scibot 24 Nov 2022
      RRID:SCR_002798

      DOI: 10.1016/j.celrep.2022.111673

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    sciencedirect.com/science/article/pii/S2211124722015479
  28. www.sciencedirect.com www.sciencedirect.com
    Prenatal inflammation perturbs murine fetal hematopoietic development and causes persistent changes to postnatal immunity
    1
    1. scibot 24 Nov 2022
      RRID:SCR_015807

      DOI: 10.1016/j.celrep.2022.111677

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    sciencedirect.com/science/article/pii/S2211124722015510
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A role for the centrosome in regulating the rate of neuronal efferocytosis by microglia in vivo
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    1. scibot 24 Nov 2022
      RRID:SCR_002798

      DOI: 10.7554/eLife.82094

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    ncbi.nlm.nih.gov/pmc/articles/PMC9674339/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Learning-related contraction of gray matter in rodent sensorimotor cortex is associated with adaptive myelination
    1
    1. scibot 23 Nov 2022
      RRID:SCR_002798

      DOI: 10.7554/eLife.77432

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    ncbi.nlm.nih.gov/pmc/articles/PMC9678357/
  31. www.sciencedirect.com www.sciencedirect.com
    Acute changes in systemic glycemia gate access and action of GLP-1R agonist on brain structures controlling energy homeostasis
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    1. scibot 23 Nov 2022
      RRID:SCR_002798

      DOI: 10.1016/j.celrep.2022.111698

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    sciencedirect.com/science/article/pii/S2211124722015728
  32. www.mdpi.com www.mdpi.com
    Decitabine Treatment Induces a Viral Mimicry Response in Cervical Cancer Cells and Further Sensitizes Cells to Chemotherapy
    1
    1. scibot 22 Nov 2022
      RRID:SCR_002798

      DOI: 10.3390/ijms232214042

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    mdpi.com/1422-0067/23/22/14042
  33. aacrjournals.org aacrjournals.org
    A novel selective inhibitor JBI-589 targets PAD4-mediated neutrophil migration to suppress tumor progression
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    1. scibot 22 Nov 2022
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      DOI: 10.1158/0008-5472.CAN-21-4045

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    aacrjournals.org/cancerres/article/82/19/3561/709408/A-Novel-Selective-Inhibitor-JBI-589-Targets-PAD4
  34. aacrjournals.org aacrjournals.org
    Plasma CD27, a surrogate of the intratumoral CD27-CD70 interaction, correlates with immunotherapy resistance in renal cell carcinoma
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1158/1078-0432.CCR-22-0905

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    aacrjournals.org/clincancerres/article/28/22/4983/710467/Plasma-CD27-a-Surrogate-of-the-Intratumoral-CD27
  35. aacrjournals.org aacrjournals.org
    p53 inhibits Bmi-1-driven self-renewal and defines salivary gland cancer stemness
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1158/1078-0432.CCR-22-1357

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    aacrjournals.org/clincancerres/article/28/21/4757/709842/p53-Inhibits-Bmi-1-driven-Self-Renewal-and-Defines
  36. aacrjournals.org aacrjournals.org
    A druggable UHRF1/DNMT1/GLI complex regulates Sonic hedgehog dependent tumor growth
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1158/1541-7786.MCR-22-0182

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    aacrjournals.org/mcr/article/20/11/1598/709855/A-Druggable-UHRF1-DNMT1-GLI-Complex-Regulates
  37. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Continued P2X7 Activation Leads to Mitochondrial Fission and Compromising Microglial Phagocytosis after Subarachnoid Haemorrhage
    1
    1. scibot 22 Nov 2022
      RRID:SCR_002798

      DOI: 10.1111/jnc.15712

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15712
  38. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Lysophosphatidic acid signaling via LPA6: a negative modulator of developmental oligodendrocyte maturation
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1111/jnc.15696

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    onlinelibrary.wiley.com/doi/10.1111/jnc.15696
  39. academic.oup.com academic.oup.com
    GIP affects hepatic fat and brown adipose tissue thermogenesis, but not white adipose tissue transcriptome in T1D
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1210/clinem/dgac542

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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgac542/6701885
  40. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
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    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
  41. www.sciencedirect.com www.sciencedirect.com
    Structure of a TOC-TIC supercomplex spanning two chloroplast envelope membranes
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.cell.2022.10.030

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    sciencedirect.com/science/article/pii/S0092867422013769
  42. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide and calcipotriol counteract UVB-induced photoaging on primary human dermal fibroblasts.
    1
    1. scibot 22 Nov 2022
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      DOI: 10.1016/j.jpap.2022.100158

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    Initiation of 3,3-dimethyl-1-butanol at midlife prevents endothelial dysfunction and attenuates in vivo aortic stiffening with ageing in mice
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    Aberrant BCAA Accumulation along the Microbiota-Gut-Brain Axis:Crucial Targets Affecting the Occurrence and Treatment of Ischemic Stroke
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    POLθ prevents MRE11-NBS1-CtIP-dependent fork breakage in the absence of BRCA2/RAD51 by filling lagging-strand gaps
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    Identification of phosphorylation site on PARP1 mediating its cytosolic translocation in virus-infected HeLa cells
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    CD8+ T cell metabolic rewiring defined by scRNA-seq identifies a critical role of ASNS expression dynamics in T cell differentiation
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    Extensive preclinical validation of combined RMC-4550 and LY3214996 supports clinical investigation for KRAS mutant pancreatic cancer
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    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
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    Yishen-Qingli-Huoxue Formula attenuates renal fibrosis by inhibiting indoxyl sulfate via AhR/snai1 signaling
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    Regulation of mitophagy by the NSL complex underlies genetic risk for Parkinson’s disease at 16q11.2 and MAPT H1 loci
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  84. www.exphem.org www.exphem.org
    Cdkn2a inactivation promotes malignant transformation of mouse immature thymocytes before the β-selection checkpoint
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    Spatial repellents transfluthrin and metofluthrin affect the behavior of Dermacentor variabilis, Amblyomma americanum, and Ixodes scapularis in an in vitro vertical climb assay
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    Fluoxetine shows neuroprotective effects against LPS-induced neuroinflammation via the Notch signaling pathway
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    Purification of exosome-enriched proteins produced in a Drosophila cell line by size exclusion chromatography
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    Transcriptional Profiling of Phagocytic Leukocytes and Microglia Reveals a Critical Role for Reactive Oxygen Species in Biofilm Containment during Staphylococcus aureus Craniotomy Infection
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    Cardiac myosin-specific autoimmune T cells contribute to immune-checkpoint-inhibitor-associated myocarditis
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    Colonic innate immune defenses and microbiota alterations in acute swine dysentery
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    Co-immunization with hemagglutinin stem immunogens elicits cross-group neutralizing antibodies and broad protection against influenza A viruses
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    Ketone Body Augmentation Decreases Methacholine Hyperresponsiveness in Mouse Models of Allergic Asthma
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    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
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    Traumatic axonopathy in spinal tracts after impact acceleration head injury: Ultrastructural observations and evidence of SARM1-dependent axonal degeneration
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    Identification and characterization of NFATc1+ skeletal stem cells in bone regeneration
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    Extracellular vesicles from pristane-treated CD38-deficient mice express an anti-inflammatory neutrophil protein signature, which reflects the mild lupus severity elicited in these mice
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    HIV-1 Vpu restricts Fc-mediated effector functions in vivo
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    An epitope-enriched immunogen expands responses to a conserved viral site
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    Preclinical characterization and phase I clinical trial of CT053PTSA targets MET, AXL, and VEGFR2 in patients with advanced solid tumors
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    Quantification of receptor binding from response data obtained at different receptor levels: a simple individual sigmoid fitting and a unified SABRE approach
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    A circadian-dependent preference for light displayed by Xenopus tadpoles is modulated by serotonin
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    Inhibition of indoleamine 2, 3-dioxygenase in prelimbic or infralimbic cortex of ICV-STZ rats can exert antidepressant effects through different pathways
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  105. pubs.acs.org pubs.acs.org
    Subtype-Selective Positive Modulation of K Ca 2.3 Channels Increases Cilia Length
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    IL-17-induced dimerization of IL-17RA drives the formation of the IL-17 signalosome to potentiate signaling
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    Tumor-intrinsic SIRPA promotes sensitivity to checkpoint inhibition immunotherapy in melanoma
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    Opposing effects of chronic glucagon receptor agonism and antagonism on amino acids, hepatic gene expression, and alpha cells
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    De novo serine biosynthesis from glucose predicts sex-specific response to antifolates in non-small cell lung cancer cell lines
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    A systemic cell stress signal confers neuronal resilience toward oxidative stress in a Hedgehog-dependent manner
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    The Comparative Role of BAMLET and 5-Fluorouracil in Colorectal Cancer Cells by Targeting WNT/β-Catenin Pathway
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    Prolactin Action Is Necessary for Parental Behavior in Male Mice
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    Transient active zone remodeling in the Drosophila mushroom body supports memory
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    Sex-specific regulation of IL-10 production in human adipose tissue in obesity
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    FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits
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    GBA variant E326K is associated with alpha-synuclein aggregation and lipid droplet accumulation in human cell lines
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    Stellate Ganglion Block Improves Postoperative Cognitive Dysfunction in aged rats by SIRT1-mediated White Matter Lesion Repair
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    Mitoguardin-2–mediated lipid transfer preserves mitochondrial morphology and lipid droplet formation
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  123. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The NRF2 antagonist ML385 inhibits PI3K-mTOR signaling and growth of lung squamous cell carcinoma cells
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    Combinatorial treatment with exercise and AICAR potentiates the rescue of myotonic dystrophy type 1 mouse muscles in a sex-specific manner
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    Functional Magnetic Resonance Spectroscopy Study of Total Glutamate and Glutamine in the Human Visual Cortex Activated by a Short Stimulus
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    SHERLOCK4HAT: A CRISPR-based tool kit for diagnosis of Human African Trypanosomiasis
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    Investigation of Curcumin-Loaded OA400 Nanoparticle’s Effect on the Expression of E6 and E7 Human Papilloma-Virus Oncogenes and P53 and Rb Factors in HeLa Cell Line
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    Heme Oxygenase-1 Overexpression Promotes Uveal Melanoma Progression and Is Associated with Poor Clinical Outcomes
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  132. aacrjournals.org aacrjournals.org
    Sirpiglenastat (DRP-104) Induces Anti-tumor Efficacy Through Direct, Broad Antagonism of Glutamine Metabolism and Stimulation of the Innate & Adaptive Immune Systems
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  133. www.jneurosci.org www.jneurosci.org
    µ-Opioid Receptor Activation Reduces Glutamate Release in the preBötzinger Complex in Organotypic Slice Cultures
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  136. aacrjournals.org aacrjournals.org
    Notch signaling promotes mature T-cell lymphomagenesis
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    Phosphoproteomic mapping reveals distinct signaling actions and activation of muscle protein synthesis by Isthmin-1
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    Prenatal exposure to inflammation increases anxiety-like behaviors in F1 and F2 generations: possible links to decreased FABP7 in hippocampus
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    Lateral septum modulates cortical state to tune responsivity to threat stimuli
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    Interval between prior SARS-CoV-2 infection and booster vaccination impacts magnitude and quality of antibody and B cell responses
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    Murine endothelial serine palmitoyltransferase 1 (SPTLC1) is required for vascular development and systemic sphingolipid homeostasis
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    T cell kinetics reveal expansion of distinct lung T cell subsets in acute versus in resolved influenza virus infection
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    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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    Interleukin-33-activated neuropeptide CGRP-producing memory Th2 cells cooperate with somatosensory neurons to induce conjunctival itch
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    Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin
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    Effectiveness, survival and safety of guselkumab attending to basal characteristics in moderate-to-severe psoriatic patients: a cohort study
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    Mapping brain gene coexpression in daytime transcriptomes unveils diurnal molecular networks and deciphers perturbation gene signatures
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    Bisphenol A exacerbates selenium deficiency-induced pyroptosis via the NF-κB/NLRP3/Caspase-1 pathway in chicken trachea
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    Enhanced delivery of antibodies across the blood-brain barrier via TEMs with inherent receptor-mediated phagocytosis
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    A feed-forward pathway drives LRRK2 kinase membrane recruitment and activation
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    Sorbitol dehydrogenase induction of cancer cell necroptosis and macrophage polarization in the HCC microenvironment suppresses tumor progression
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    Root twisting drives halotropism via stress-induced microtubule reorientation
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    The Cancermuts software package for the prioritization of missense cancer variants: a case study of AMBRA1 in melanoma
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    Cannabinoids and Opioids Differentially Target Extrinsic and Intrinsic GABAergic Inputs onto the Periaqueductal Grey Descending Pathway
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    Lifespan changes in cannabinoid 1 receptor mRNA expression in the female C57BL/6J mouse brain
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    Experiences Shape Hippocampal Neuron Morphology and the Local Levels of CRHR1 and OTR
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    BefA, a microbiota-secreted membrane disrupter, disseminates to the pancreas and increases β cell mass
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    Hyperactivation of mTORC1 in a double hit mutant zebrafish model of tuberous sclerosis complex causes increased seizure susceptibility and neurodevelopmental abnormalities
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    Cannabinoid signaling modulation through JZL184 restores key phenotypes of a mouse model for Williams–Beuren syndrome
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    Targeted RNA editing in brainstem alleviates respiratory dysfunction in a mouse model of Rett syndrome
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    Differential plasticity and fate of brain-resident and recruited macrophages during the onset and resolution of neuroinflammation
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    Multiomic characterization and drug testing establish circulating tumor cells as an ex vivo tool for personalized medicine
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    A Microarray Patch SARS-CoV-2 Vaccine Induces Sustained Antibody Responses and Polyfunctional Cellular Immunity
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    Memory CD4+ T cells that co-express PD1 and CTLA4 have reduced response to activating stimuli facilitating HIV latency
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    Oxytocin and orexin systems bidirectionally regulate the ability of opioid cues to bias reward seeking
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