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52.53.155.43 52.53.155.43

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1. scibot 13 Apr 2025
  
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  DOI: 10.1158/1078-0432.ccr-24-4024
  
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52.53.155.43 52.53.155.43

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1. scibot 12 Apr 2025
  
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  DOI: 10.1158/1078-0432.ccr-24-3490
  
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52.53.155.43/00e9dc67e853b9ce3c8607a88ed8f4004b5fcfd9/PDF-html.html
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The bridge-like lipid transport protein VPS13C/PARK23 mediates ER–lysosome contacts following lysosome damage

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1. scibot 11 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1038/s41556-025-01653-6
  
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An integrated microfluidic and fluorescence platform for probing in vivo neuropharmacology

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1. scibot 11 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1016/j.neuron.2025.03.017
  
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A sensitive period for the development of episodic-like memory in mice

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1. scibot 11 Apr 2025
  
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  DOI: 10.1016/j.cub.2025.03.032
  
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Cholesterol taste avoidance in Drosophila melanogaster

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1. scibot 10 Apr 2025
  
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  DOI: 10.7554/eLife.106256.1
  
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Ginsenoside Rh2 regulates cardiomyocyte autophagy-dependent apoptosis through the PI3K-Akt-mTOR signaling pathway to attenuate doxorubicin-induced cardiotoxicity

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1. scibot 10 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1186/s13765-025-00986-y
  
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52.53.155.43 52.53.155.43

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1. scibot 10 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1158/1541-7786.mcr-24-0957
  
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52.53.155.43/009f5d6e39c430064ce0b832cf798a7e9caafb80/PDF-html.html
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Astrocytic polyamine transport by ATP13A4 tunes excitatory synaptic transmission

1
1. scibot 10 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1101/2025.04.04.25325117
  
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medrxiv.org/content/10.1101/2025.04.04.25325117v1
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A cloaked human stem-cell-derived neural graft capable of functional integration and immune evasion in rodent models

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.stem.2025.03.008
  
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Single-neuron projectome reveals organization of somatosensory ascending pathways in the mouse brain

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.neuron.2025.03.007
  
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Viral vaccines promote endoplasmic reticulum stress-induced unfolding protein response in teleost erythrocytes

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.ejcb.2025.151490
  
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CD44 Identified as a Diagnostic Biomarker for Highly Malignant CA19-9 Negative Pancreatic Cancer

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1. scibot 10 Apr 2025
  
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  DOI: 10.1016/j.canlet.2025.217713
  
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N6-methyladenosine in DNA promotes genome stability

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1. scibot 09 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.7554/eLife.101626
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11975372/
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A gold nanoparticle/peptide vaccine designed to induce SARS-CoV-2-specific CD8 T cells: a double-blind, randomized, phase 1 study in Switzerland

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1. scibot 09 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1186/s12879-025-10844-3
  
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Intestinal secretory differentiation reflects niche-driven phenotypic and epigenetic plasticity of a common signal-responsive terminal cell

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1. scibot 09 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1016/j.stem.2025.03.005
  
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Mitochondrial DNA released by senescent tumor cells enhances PMN-MDSC-driven immunosuppression through the cGAS-STING pathway

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.immuni.2025.03.005
  
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Transcriptional conservation and evolutionary divergence of cell types across mammalian hypothalamus development

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.devcel.2025.03.009
  
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Quiescent cell re-entry is limited by macroautophagy-induced lysosomal damage

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1. scibot 09 Apr 2025
  
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  DOI: 10.1016/j.cell.2025.03.009
  
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sciencedirect.com/science/article/pii/S009286742500282X
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Airway specific deregulation of asthma-related serpins impairs tracheal architecture and oxygenation in D. melanogaster

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1. scibot 08 Apr 2025
  
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  DOI: 10.1038/s41598-024-66752-0
  
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Mechanism of ceramide synthase inhibition by fumonisin B1

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.str.2024.06.002
  
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Chaperone-assisted cryo-EM structure of P. aeruginosa PhuR reveals molecular basis for heme binding

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  Prism 9.0
  
  DOI: 10.1016/j.str.2024.01.007
  
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Structural insights into the FtsEX-EnvC complex regulation on septal peptidoglycan hydrolysis in Vibrio cholerae

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1. scibot 08 Apr 2025
  
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  GraphPad Prism 8
  
  DOI: 10.1016/j.str.2023.11.007
  
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Doublet microtubule inner junction protein FAP20 recruits tubulin to the microtubule lattice

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.str.2023.09.010
  
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Stratification of enterochromaffin cells by single-cell expression analysis

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1. scibot 08 Apr 2025
  
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  DOI: 10.7554/eLife.90596
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970908/
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CXXC-finger protein 1 associates with FOXP3 to stabilize homeostasis and suppressive functions of regulatory T cells

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1. scibot 08 Apr 2025
  
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  DOI: 10.7554/eLife.103417
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11970909/
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Protocol for observing tunneling nanotube formation and function in both fixed and live primary mouse neurons and microglia coculture system

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1. scibot 08 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1016/j.xpro.2025.103723
  
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Establishing a comprehensive panel of patient-derived xenograft models for high-grade endometrial carcinoma: molecular subtypes, genetic alterations, and therapeutic target profiling

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.neo.2025.101158
  
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HNRNPC stabilizes m6A-modified AC145207.5 to accelerate tumorigenesis in colorectal cancer by impeding the Nrf2/GPX4 axis-mediated ferroptosis

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1. scibot 08 Apr 2025
  
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  DOI: 10.1016/j.ncrna.2025.04.002
  
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sciencedirect.com/science/article/pii/S2468054025000411
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Vitamin D supplementation as a prophylactic therapy in the management of pre-eclampsia: Focus on VEGF, Ki67, oxidative stress markers in correlation to placental ultra structure

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1. scibot 08 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1016/j.lfs.2025.123605
  
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sciencedirect.com/science/article/pii/S0024320525002395
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Histamine 1 Receptor (HRH1): A potential therapeutic target for Pancreatic Ductal Adenocarcinoma

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1. scibot 08 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1016/j.jpet.2025.103573
  
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sciencedirect.com/science/article/pii/S0022356525397867
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Newly generated striatal neurons rescue motor circuitry in a Huntington’s disease mouse model

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  DOI: 10.1016/j.celrep.2025.115440
  
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sciencedirect.com/science/article/pii/S2211124725002116
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Impact of heterologous expression of Cannabis sativa tetraketide synthase on Phaeodactylum tricornutum metabolic profile

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1. scibot 07 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1186/s13068-025-02638-1
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969993/
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LNS8801: An Enantiomerically Pure Agonist of the G Protein–Coupled Estrogen Receptor Suitable for Clinical Development

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1. scibot 07 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1158/2767-9764.CRC-24-0632
  
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pmc.ncbi.nlm.nih.gov/articles/PMC11969138/
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Harmine promotes axon regeneration through enhancing glucose metabolism

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1. scibot 07 Apr 2025
  
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  DOI: 10.1016/j.jbc.2025.108254
  
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Apr 2025
52.53.155.43 52.53.155.43

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1. scibot 06 Apr 2025
  
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  RRID:SCR_002798
  
  DOI: 10.1101/2025.04.01.646648
  
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52.53.155.43/3ea6483f2803c23587cd02bb657f1ea0f411dd10/PDF-html.html
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Synaptic deregulation of cholinergic projection neurons causes olfactory dysfunction across five fly Parkinsonism models

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1. scibot 05 Apr 2025
  
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  RRID:SCR_002798
  
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Alpha-synuclein knockout impairs melanoma development and alters DNA damage repair in the TG3 mouse model in a sex-dependent manner

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Comparative Evaluation of Cigarette Smoke and a Heated Tobacco Product on Corneal Oxidative Stress in an Air/Liquid Interface Model

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Profiling the Activity of the Potent and Highly Selective CDK2 Inhibitor BLU-222 Reveals Determinants of Response in CCNE1-Aberrant Ovarian and Endometrial Tumors

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STING Agonist VB-85247 Induces Durable Antitumor Immune Responses by Intravesical Administration in a Non–Muscle-Invasive Bladder Cancer

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FEBS Press

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Fatty acid uptake activates an AXL–CAV1–β-catenin axis to drive melanoma progression

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CAN-Scan: A multi-omic phenotype-driven precision oncology platform identifies prognostic biomarkers of therapy response for colorectal cancer

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The Chlamydia effector Dre1 binds dynactin to reposition host organelles during infection

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Neuropeptide oxytocin facilitates its own brain-to-periphery uptake

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RAF1 kinase contributes to autophagic lysosome reformation

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LIG1 Is a Synthetic Lethal Target in BRCA1 Mutant Cancers

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Modulating immune responses in alopecia: therapeutic insights and potential targets of antisense oligonucleotides

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Trabectedin Enhances the Antitumor Effects of IL-12 in Triple-Negative Breast Cancer

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PRDM1 Is a Key Regulator of the NKT-cell Central Memory Program and Effector Function

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Identification of a TNIK-CDK9 Axis as a Targetable Strategy for Platinum-Resistant Ovarian Cancer

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VAX014 Activates Tumor-Intrinsic STING and RIG-I to Promote the Development of Antitumor Immunity

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Novel Amanitin-Based Antibody–Drug Conjugates Targeting TROP2 for the Treatment of Pancreatic Cancer

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Combination of Bremachlorin PDT and Immune Checkpoint Inhibitor Anti–PD-1 Shows Response in Murine Immunological T-cell–High and T-cell–Low PDAC Models

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BCL-XL Protects ASS1-Deficient Cancers from Arginine Starvation–Induced Apoptosis

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A Phase I Clinical Trial of Intrahepatic Artery Delivery of TG6002 in Combination with Oral 5-Fluorocytosine in Patients with Liver-Dominant Metastatic Colorectal Cancer

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BPS Publications

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Cryo-EM Structure of K+-Bound hERG Channel Complexed with the Blocker Astemizole

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Rab10 regulates neuropeptide release by maintaining Ca2+ homeostasis and protein synthesis

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Peripheral opioid receptor antagonism alleviates fentanyl-induced cardiorespiratory depression and is devoid of aversive behavior

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The Marine Compound Isaridin E Ameliorates Lipopolysaccharide-Induced Vascular Endothelial Inflammation via the Downregulation of the TLR4/NF-κB Signaling Pathway

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Comprehensive characterization of metabolic consumption and production by the human brain

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Mitochondrial fatty acid oxidation as the target for blocking therapy-resistance and inhibiting tumor recurrence: The proof-of-principle model demonstrated for ovarian cancer cells

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Taste detection of flonicamid in Drosophila melanogaster

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A spatiotemporal cell atlas of cardiopulmonary progenitor cell allocation during development

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Genetically encoded reporters of actin filament organization in living cells and tissues

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IL-18-primed NK cells recruit dendritic cells and potentiate tumor therapy mediated by PD-1 blockade

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Imipridones ONC201/ONC206 + RT/TMZ triple (IRT) therapy reduces intracranial tumor burden, prolongs survival in orthotopic IDH-WT GBM mouse model, and suppresses MGMT

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Genomic Characterization of Chondrosarcoma Reveals Potential Therapeutic Targets

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CD4+ T cell–innate immune crosstalk is critical during Staphylococcus aureus craniotomy infection

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Inhibition of histone methyltransferase EZH2 for immune interception of colorectal cancer in Lynch syndrome

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OATP1B-type Transport Function Is a Determinant of Aromatase Inhibitor–Associated Arthralgia Susceptibility

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IMGN853 Induces Autophagic Cell Death in Combination Therapy for Ovarian Cancer

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A Checkpoint Reversal Receptor Mediates Bipartite Activation and Enhances CAR T-cell Function

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Augmenting CAR T Cell Functions with LIGHT

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Pyruvate kinase modulates the link between β‐cell fructose metabolism and insulin secretion

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Sulfatase 2 inhibition sensitizes triple-negative breast cancer cells to paclitaxel through augmentation of extracellular ATP

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Loss of fatty acid-binding protein 7 promotes B16F10 melanoma metastasis

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Delta opioid receptors engage multiple signaling cascades to differentially modulate prefrontal GABA release with input and target specificity

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Office Blood Pressure and Obesity in Children with X-Linked Hypophosphatemia

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Oncogenic KRAS Addiction States Differentially Influence MTH1 Expression and 8-oxodGTPase Activity in Lung Adenocarcinoma

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Type I interferons induce guanylate-binding proteins and lysosomal defense in hepatocytes to control malaria

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The metabolic sensor LKB1 regulates ILC3 homeostasis and mitochondrial function

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CaV2.1 mediates presynaptic dysfunction induced by amyloid β oligomers

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The role of TRPV4 in acute sleep deprivation-induced memory impairment: mechanisms of calcium dysregulation and synaptic plasticity disruption

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Identifying the Intergenic ALK Fusion LOC388942-ALK as a Driver of Non–Small Cell Lung Cancer

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Interferon-Inducible ADAR1 p150 Is Essential for the Survival of Oral Squamous Cell Carcinoma

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Dynamic Changes of Serotonin Transporter Expression in the Prefrontal Cortex Evoked by Aggressive Social Interactions

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Seeded aggregation of TDP-43 induces its loss of function and reveals early pathological signatures

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Bidirectional optogenetic modulation of peripheral sensory nerve activity: Induction vs. suppression through channelrhodopsin and halorhodopsin

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Lung-resident memory B cells maintain allergic IgE responses in the respiratory tract

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Metallophilic marginal zone macrophages cross-prime CD8+ T cell-mediated protective immunity against blood-borne tumors

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Long-lasting B cell convergence to distinct broadly reactive epitopes following vaccination with chimeric influenza virus hemagglutinins

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Single-cell transcriptomic and functional studies identify glial state changes and a role for inflammatory RIPK1 signaling in ALS pathogenesis

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Efflux pump modulation by Montelukast and its roles in restoring antibiotic susceptibility in multidrug-resistant Staphylococcus aureus

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Lineage contribution of the mesendoderm progenitors in the gastrulating mouse embryo

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PDZD8 promotes autophagy at ER-lysosome membrane contact sites to regulate activity-dependent synaptic growth

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Antagonistic roles for MITF and TFE3 in melanoma plasticity

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Identification of a new micropeptide altKLF4 derived from KLF4 that influences myeloma chemotherapeutic sensitivity

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Opposing roles for Bmp signalling during the development of electrosensory lateral line organs

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Carbamoylated Erythropoietin Rescues Autism-Relevant Social Deficits in BALB/cJ Mice

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Chromosomal Instability Is Associated with cGAS–STING Activation in EGFR-TKI Refractory Non-Small-Cell Lung Cancer

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Transcriptome Analysis of Canine Histiocytic Sarcoma Tumors and Cell Lines Reveals Multiple Targets for Therapy

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Low-Intensity Blast Exposure Induces Multifaceted Long-Lasting Anxiety-Related Behaviors in Mice

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Precisely tuning the electronic states of organic polymer electrocatalysts via thiophene-based moieties for enhanced oxygen reduction reaction

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23ME-01473, an Fc Effector–Enhanced Anti-ULBP6/2/5 Antibody, Restores NK Cell–Mediated Antitumor Immunity through NKG2D and FcγRIIIa Activation

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Perimenopause promotes neuroinflammation in select hippocampal regions in a mouse model of Alzheimer’s disease

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Drosophila complement-like Mcr acts as a wound-induced inflammatory chemoattractant

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Preconception maternal gut dysbiosis affects enteric nervous system development and disease susceptibility in offspring via the GPR41–GDNF/RET/SOX10 signaling pathway

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Ultrastructural Contributions to Extrasynaptic Glutamatergic Signaling in Olfactory Bulb Glomeruli

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Hippocampal Inhibitory Interneuron-Specific DREADDs Treatment Alters mTORC1-4E-BP Signaling and Impairs Memory Formation

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Proximity proteomics reveals unique and shared pathological features between multiple system atrophy and Parkinson’s disease

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Targeting WEE1 kinase as a therapeutic strategy in ATIP3-deficient breast cancers

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S-hydroxychloroquine prevents the antiphospholipid thrombogenic complexes for antiphospholipid syndrome treatment

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The carnosinase dipeptidase CNDP1 is a novel metabolic vulnerability in brain metastasis

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Homeodomain protein PRRX1 anchors the Ku heterodimers at DNA double-strand breaks to promote nonhomologous end-joining

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Bovine Meat and Milk Factor (BMMF) Protein Is Expressed in Macrophages Spread Widely over the Mucosa of Colorectal Cancer Patients

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The nuclear pore complex connects energy sensing to transcriptional plasticity in longevity

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Spatial genomics of AAV vectors reveals mechanism of transcriptional crosstalk that enables targeted delivery of large genetic cargo

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Investigating Neotenic and Metamorphic Axolotl Brain Complexity: A Stereological and Immunohistochemical Perspective

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Induction of Triple-Negative Breast Cancer Cell Death and Chemosensitivity Using mTORC2-Directed RNAi Nanomedicine

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Expression of a single inhibitory member of the Ly49 receptor family is sufficient to license NK cells for effector functions

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Oxytocin signaling in the ventral tegmental area mediates social isolation-induced craving for social interaction

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Immune Checkpoint Blockade Delays Cancer Development and Extends Survival in DNA Polymerase Mutator Syndromes

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Physical Activity Decreases Inflammation and Delays Development of Obesity-Associated Pancreatic Ductal Adenocarcinoma

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The mechanosensitive channel ELKIN1 regulates cellular adaptations to simulated microgravity

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Gene therapy rescues brain edema and motor function in a mouse model of megalencephalic leukoencephalopathy with subcortical cysts

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T-bet+ CXCR3+ B cells drive hyperreactive B-T cell interactions in multiple sclerosis

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Subacute Exposure of Male Adolescent Rats to 2,2',5,5'-Tetrachlorobiphenyl-4-ol via a Polymeric Implant Causes Gene Expression Changes in the Brain and Metabolomic Disruption in Serum

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m6A deficiency impairs hypothalamic neurogenesis of feeding-related neurons in mice and human organoids and leads to adult obesity in mice

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Sex-dependent effects of stress on aIC-NAc circuit neuroplasticity: Role of the endocannabinoid system

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A transcriptional atlas of gut-innervating neurons reveals activation of interferon signaling and ferroptosis during intestinal inflammation

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Spatial control of m6A deposition on enhancer and promoter RNAs through co-acetylation of METTL3 and H3K27 on chromatin

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An interleukin-9-ZBTB18 axis promotes germinal center development of memory B cells

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Anti-vascular endothelial growth factor treatment potentiates immune checkpoint blockade through a BAFF- and IL-12-dependent reprogramming of the TME

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Sex-specific neurons instruct sexually dimorphic neurite branching via Netrin signaling in Caenorhabditis elegans

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Nonlinear high-activity neuronal excitation enhances odor discrimination

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Macrophage-specific PHGDH protects against MAFLD by suppressing TAK1

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Genome-wide mutagenesis identifies factors involved in MRSA vaginal colonization

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Growth of the maternal intestine during reproduction

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Keloid vasculature reacts to intralesional injection therapies but does not predict the response to treatment: Biopsies from double-blinded, randomized, controlled trial

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Long-term CSF responses in adult patients with spinal muscular atrophy type 2 or 3 on treatment with nusinersen

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NXP800 Activates the Unfolded Protein Response, Altering AR and E2F Function to Impact Castration-Resistant Prostate Cancer Growth

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Impact of Co-mutations and Transcriptional Signatures in Non–Small Cell Lung Cancer Patients Treated with Adagrasib in the KRYSTAL-1 Trial

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Dual independent mechanisms underlying gut epithelial remodeling upon sugar substitute consumption

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PIF/harbinger transposon-derived protein promotes 7SL expression to enhance pathogen resistance

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Benefits of Dietary Supplementation with Specific Silicon-Enriched Spirulina on Arterial Function in Healthy Elderly Individuals: A Randomized, Placebo-Controlled Trial

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Characterization of the Temporal Dynamics of the Endothelial–Mesenchymal-like Transition Induced by Soluble Factors from Dengue Virus Infection in Microvascular Endothelial Cells

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The Evolutionary Young Actin Nucleator Cobl Is Important for Proper Amelogenesis

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Tumor-localized interleukin-2 and interleukin-12 combine with radiation therapy to safely potentiate regression of advanced malignant melanoma in pet dogs

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Protective ApoE variants support neuronal function by extracting peroxidated lipids

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PDF-html.html

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Protocol for the simultaneous activation and lentiviral transduction of primary human T cells with artificial T cell receptors

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Effective targeting of PDGFRA-altered high-grade glioma with avapritinib

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Translatome analysis reveals cellular network in DLK-dependent hippocampal glutamatergic neuron degeneration

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UNC-6/Netrin promotes both adhesion and directed growth within a single axon

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Circulating RNA Markers Associated with Adenoma–Carcinoma Sequence in Colorectal Cancer

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Determining the Bordetella LPS structural features that influence TLR4 downstream signaling

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Biological boundary conditions regulate the internalization of Aspergillus fumigatus conidia by alveolar cells

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BKT300: A Novel Anti-Leukemic Small Molecule Targeting the Protein Regulator of Cytokinesis 1 (PRC1) Pathway

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Identification of a conserved subset of cold tumors responsive to immune checkpoint blockade

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Nobiletin‐mediated autophagy mitigates nanoplastic‐induced toxicity in human intestinal Caco‐2 cells

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A phase II trial of mTORC1/2 inhibition in STK11 deficient non small cell lung cancer

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  DOI: 10.1038/s41698-025-00838-4
  
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PTPσ-mediated PI3P regulation modulates neurodegeneration in C9ORF72-ALS/FTD

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1-s2.0-S2589004225004535-main-html.html

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1-s2.0-S2589004225004419-main (1)-html.html

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Protocol for characterizing airway epithelial ciliary beating and mucociliary transport using image processing and particle imaging velocimetry

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PRMT3 drives PD-L1-mediated immune escape through activating PDHK1-regulated glycolysis in hepatocellular carcinoma

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LTA4H improves the tumor microenvironment and prevents HCC progression via targeting the HNRNPA1/LTBP1/TGF-β axis

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Single extracellular vesicle detection assay identifies membrane-associated α-synuclein as an early-stage biomarker in Parkinson’s disease

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Antibody-DNA nanostructure conjugate enables targeted delivery of gemcitabine to tumor and improves the anti-tumor efficacy

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Low-dose irradiation of the gut improves the efficacy of PD-L1 blockade in metastatic cancer patients

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Impaired yolk sac NAD metabolism disrupts murine embryogenesis with relevance to human birth defects

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  DOI: 10.7554/eLife.97649
  
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A comprehensive study on the impact of Ligustrum vicaryi L. fruit polysaccharide on myocardial fibrosis through animal experiments, network pharmacology and molecular docking

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Targeting adenosine enhances immunotherapy in MSS colorectal cancer with EGFRvIII mutation

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Chronic in vivo sequelae of repetitive acute mfb-DBS on accumbal dopamine and midbrain neuronal activity

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