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  1. Jan 2022
  2. www.sciencedirect.com www.sciencedirect.com
    Acute restraint stress redirects prefrontal cortex circuit function through mGlu5 receptor plasticity on somatostatin-expressing interneurons
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      DOI: 10.1016/j.neuron.2021.12.027

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    sciencedirect.com/science/article/pii/S0896627321010448
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    Deregulation of the CD44-NANOG-MDR1 associated chemoresistance pathways of breast cancer stem cells potentiates the anti-cancer effect of Kaempferol in synergism with Verapamil
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    1. scibot 26 Jan 2022
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    The subthalamic corticotropin-releasing hormone neurons mediate adaptive REM-sleep responses to threat
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    Fine-tuning of β-catenin in mouse thymic epithelial cells is required for postnatal T-cell development
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    ACE2 pathway regulates thermogenesis and energy metabolism
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    Lipocalin 2 Influences Bone and Muscle Phenotype in the MDX Mouse Model of Duchenne Muscular Dystrophy
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    Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3
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    Acetylated α-tubulin K394 regulates microtubule stability to shape the growth of axon terminals
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    Endothelial p130cas confers resistance to anti-angiogenesis therapy
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    Amino acid starvation-induced LDLR trafficking accelerates lipoprotein endocytosis and LDL clearance
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      DOI: 10.15252/embr.202153373

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    Circadian Transcription Factor NPAS2 and the NAD+-Dependent Deacetylase SIRT1 Interact in the Mouse Nucleus Accumbens and Regulate Reward
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      DOI: 10.1111/ejn.15596

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    Type I and II PRMTs inversely regulate post-transcriptional intron detention through Sm and CHTOP methylation
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      DOI: 10.7554/eLife.72867

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    Notch2 Increases the Resistance to Venetoclax-Induced Apoptosis in Chronic Lymphocytic Leukemia B Cells by Inducing Mcl-1
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    The TZM-bl Reporter Cell Line Expresses Kynureninase That Can Neutralize 2F5-like Antibodies in the HIV-1 Neutralization Assay
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    1. scibot 22 Jan 2022
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      DOI: 10.3390/ijms23020641

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    PRC1 sustains the integrity of neural fate in the absence of PRC2 function
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      DOI: 10.7554/eLife.72769

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    Hepatic microRNA modulation might be an early event to non-alcoholic fatty liver disease development driven by high-fat diet in male mice
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      DOI: 10.1007/s11033-021-07072-8

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    A quantitative RT-PCR protocol to adapt and quantify RBM20-dependent exon splicing of targets at the human locus
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      DOI: 10.1016/j.xpro.2021.101117

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    A fluorescence recovery after photobleaching protocol to measure surface diffusion of DAGLα in primary cultured cortical mouse neurons
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      DOI: 10.1016/j.xpro.2021.101118

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    Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment
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    Hepatic MIR20B promotes nonalcoholic fatty liver disease by suppressing PPARA
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      DOI: 10.7554/eLife.70472

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    Neurotoxin-mediated potent activation of the axon degeneration regulator SARM1
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      DOI: 10.7554/eLife.72823

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    The Role of NF-kB in the Downregulation of Organic Cation Transporter 2 Expression and Renal Cation Secretion in Kidney Disease
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      DOI: 10.3389/fmed.2021.800421

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    Lipid droplet dynamics regulate adult muscle stem cell fate
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    Pegylated arginine deiminase drives arginine turnover and systemic autophagy to dictate energy metabolism
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      DOI: 10.1016/j.xcrm.2021.100498

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    SARS-CoV-2 infects the human kidney and drives fibrosis in kidney organoids
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      DOI: 10.1016/j.stem.2021.12.010

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    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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      DOI: 10.1016/j.crmeth.2021.100153

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    Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
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      DOI: 10.7554/eLife.71052

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    Clathrin-independent endocytic retrieval of SV proteins mediated by the clathrin adaptor AP-2 at mammalian central synapses
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      DOI: 10.7554/eLife.71198

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    De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
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    Identification of a stereotypic molecular arrangement of endogenous glycine receptors at spinal cord synapses
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      DOI: 10.7554/eLife.74441

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    Comparative transcriptomic analysis reveals translationally relevant processes in mouse models of malaria
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    A protocol to investigate cellular and circuit mechanisms generating sharp wave ripple oscillations in rodent basolateral amygdala using ex vivo slices
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    Mechanisms of Carboxylic Acid Attraction in Drosophila melanogaster
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    Coordinate control of basal epithelial cell fate and stem cell maintenance by core EMT transcription factor Zeb1
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    Sex-dependent influence of postweaning environmental enrichment in Angelman syndrome model mice
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      DOI: 10.1002/brb3.2468

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    Borna disease virus docks on neuronal DNA double-strand breaks to replicate and dampens neuronal activity
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      DOI: 10.1016/j.isci.2021.103621

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    IL-27 induces IFN/STAT1-dependent genes and enhances function of TIGIT+ HIVGag-specific T cells
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    Antibacterial activity of supernatants of Lactoccocus lactis, Lactobacillus rhamnosus, Pediococcus pentosaceus and curcumin against Aeromonas hydrophila. In vitro study
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      DOI: 10.1007/s11259-021-09871-7

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    Salivary ZG16B expression loss follows exocrine gland dysfunction related to oral Chronic Graft-Versus-Host Disease
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    Inhibition of TRPM2 by AG490 Is Neuroprotective in a Parkinson’s Disease Animal Model
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      DOI: 10.1007/s12035-022-02723-8

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    p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function
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    Interaction of α9α10 Nicotinic Receptors With Peptides and Proteins From Animal Venoms
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    Structure-guided glyco-engineering of ACE2 for improved potency as soluble SARS-CoV-2 decoy receptor
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    Self-developed NF-κB inhibitor 270 protects against LPS-induced acute kidney injury and lung injury through improving inflammation
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    Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy
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    PI3K inhibition by BKM120 results in anti-proliferative effects on corticotroph tumor cells
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    Chromatin alterations during the epididymal maturation of mouse sperm refine the paternally inherited epigenome
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    Tissue-type plasminogen activator induces TNF-α-mediated preconditioning of the blood-brain barrier - Ariel Diaz, Yena Woo, Cynthia Martin-Jimenez, Paola Merino, Enrique Torre, Manuel Yepes, 2021
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    Transcriptional profiling of sequentially generated septal neuron fates
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    Supracellular organization confers directionality and mechanical potency to migrating pairs of cardiopharyngeal progenitor cells
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    Constitutive deficiency of the neurogenic hippocampal modulator AP2γ promotes anxiety-like behavior and cumulative memory deficits in mice from juvenile to adult periods
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    Convergent, functionally independent signaling by mu and delta opioid receptors in hippocampal parvalbumin interneurons
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    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen
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    Compound screen identifies the small molecule Q34 as an inhibitor of SARS-CoV-2 infection
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    Defining the interactome of the human mitochondrial ribosome identifies SMIM4 and TMEM223 as respiratory chain assembly factors
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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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    mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
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    Soluble TAM receptors sAXL and sTyro3 predict structural and functional protection in Alzheimer’s disease
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    Skeletal muscle phenotyping of Hippo gene-mutated mice reveals that Lats1 deletion increases the percentage of type I muscle fibers
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    Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
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    AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer
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    MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1
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    Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors
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    Rewired glycosylation activity promotes scarless regeneration and functional recovery in spiny mice after complete spinal cord transection
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    Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells
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    CXCL4 drives fibrosis by promoting several key cellular and molecular processes
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    Glutamate in primary afferents is required for itch transmission
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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    Calcium-dependent ESCRT recruitment and lysosome exocytosis maintain epithelial integrity during Candida albicans invasion
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    Phosphatidylmannoside prevents obesity induced by high-fat feeding
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    Relationship between biodosimetric parameters and treatment volumes in three types of prostate radiotherapy
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    Transcriptome analysis reveals the contribution of oligodendrocyte and radial glia-derived cues for maintenance of microglia identity
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    Morphological profiling by means of the Cell Painting assay enables identification of tubulin-targeting compounds
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    The Protective Mechanism of Deuterated Linoleic Acid Involves the Activation of the Ca2+ Signaling System of Astrocytes in Ischemia In Vitro
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    Developmental Disruption of Erbb4 in Pet1+ Neurons Impairs Serotonergic Sub-System Connectivity and Memory Formation
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    IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells
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    Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila
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    Kel1 is a phosphorylation-regulated noise suppressor of the pheromone signaling pathway
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    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
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    Adult-onset hypothyroidism causes mechanical hypersensitivity due to peripheral nerve hyperexcitability based on voltage-gated potassium channel downregulation in male mice
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    Sexual dimorphism in neurological function after SCI is associated with disrupted neuroinflammation in both injured spinal cord and brain
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    Tissue-type plasminogen activator induces TNF-α-mediated preconditioning of the blood-brain barrier - Ariel Diaz, Yena Woo, Cynthia Martin-Jimenez, Paola Merino, Enrique Torre, Manuel Yepes, 2021
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    A sensitive GRAB sensor for detecting extracellular ATP in vitro and in vivo
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    PAK4-NAMPT Dual Inhibition Sensitizes Pancreatic Neuroendocrine Tumors to Everolimus
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    Oxidized Low-Density Lipoprotein Links Hypercholesterolemia and Bladder Cancer Aggressiveness by Promoting Cancer Stemness
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    Muscarinic signaling regulates voltage-gated potassium channel KCNQ2 phosphorylation in the nucleus accumbens via protein kinase C for aversive learning
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    Neuronal membrane glycoprotein (nmgp-1) gene deficiency affects chemosensation-related behaviors, dauer exit and egg-laying in Caenorhabditis elegans
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    Behavioural and neurochemical effects after repeated administration of N-ethylpentylone (ephylone) in mice
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    Ocimum basilicum but not Ocimum gratissimum present cytotoxic effects on human breast cancer cell line MCF-7, inducing apoptosis and triggering mTOR/Akt/p70S6K pathway
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    Tmem160 contributes to the establishment of discrete nerve injury-induced pain behaviors in male mice
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    PAK5 promotes RNA helicase DDX5 sumoylation and miRNA-10b processing in a kinase-dependent manner in breast cancer
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    Astroglial ER-mitochondria calcium transfer mediates endocannabinoid-dependent synaptic integration
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    Potent macrocycle inhibitors of the human SAGA deubiquitinating module
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    Analgesic α-conotoxins modulate native and recombinant GIRK1/2 channels via GABAB receptor activation and reduce neuroexcitability
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      DOI: 10.1111/bph.15690

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    A novel CARM1-HuR axis involved in muscle differentiation and plasticity misregulated in spinal muscular atrophy
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    Long-Range Monosynaptic Inputs Targeting Apical and Basal Dendrites of Primary Motor Cortex Deep Output Neurons
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    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
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    Disrupted expression of mitochondrial NCLX sensitizes neuroglial networks to excitotoxic stimuli and renders synaptic activity toxic
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    Ethanol consumption during gestation promotes placental alterations in IGF-1 deficient mice
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    Enteric virome negatively affects seroconversion following oral rotavirus vaccination in a longitudinally sampled cohort of Ghanaian infants
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    Coronary blood vessels from distinct origins converge to equivalent states during mouse and human development
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    DNA repair enzyme NEIL3 enables a stable neural representation of space by shaping transcription in hippocampal neurons
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    Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2
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    Combining a CAR and a chimeric costimulatory receptor enhances T cell sensitivity to low antigen density and promotes persistence
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    Genetic Variants of Fatty Acid Amide Hydrolase Modulate Acute Inflammatory Responses to Colitis in Adult Male Mice
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    Impact of monomeric and aggregated wild-type and A30P/A53T double-mutant α-synuclein on antioxidant mechanism and glutamate metabolic profile of cultured astrocytes
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    CA1 pyramidal cell diversity is rooted in the time of neurogenesis
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    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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    Glial Nrf2 signaling mediates the neuroprotection exerted by Gastrodia elata Blume in Lrrk2-G2019S Parkinson’s disease
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    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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    Detection of SARS-CoV-2 spike protein binding to ACE2 in living cells by TR-FRET
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    Anti-Human Herpesvirus 6 A/B Antibodies Titers Correlate With Multiple Sclerosis-Associated Retrovirus Envelope Expression
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    The onset of circulation triggers a metabolic switch required for endothelial to hematopoietic transition
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    Identification of RAS mutant biomarkers for EGFR inhibitor sensitivity using a systems biochemical approach
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    Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair
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    Vasoactive intestinal peptide exerts an excitatory effect on hypothalamic kisspeptin neurons during estrogen negative feedback
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    Pleiotropic vascular effects of ivabradine in streptozotocin-induced diabetes
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    Decreased dopaminergic inhibition of pyramidal neurons in anterior cingulate cortex maintains chronic neuropathic pain
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    Ferroptosis mediates selective motor neuron death in amyotrophic lateral sclerosis
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    Purification of astrocyte subtype based on a double reporter mice approach for downstream transcription profiling
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    The Lyme disease agent co-opts adiponectin receptor-mediated signaling in its arthropod vector
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    A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
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    Inhibition of extracellular vesicle-associated MMP2 abrogates intercellular hepatic miR-122 transfer to liver macrophages and curtails inflammation
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    STING regulates peripheral nerve regeneration and colony stimulating factor 1 receptor (CSF1R) processing in microglia
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    Elevated FBXO45 promotes liver tumorigenesis through enhancing IGF2BP1 ubiquitination and subsequent PLK1 upregulation
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    Antibiotic Resistance Pattern of Staphylococcus Aureus Isolated From Pediatrics With Ocular Infections: A 6-Year Hospital-Based Study in China
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    TLR4 Associated Signaling Disrupters as a New Means to Overcome HERV-W Envelope-Mediated Myelination Deficits
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    Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism
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    Anti-SARS-CoV-2 antibodies elicited by COVID-19 mRNA vaccine exhibit a unique glycosylation pattern
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    The Mechanisms Underlying the Protective Action of Selenium Nanoparticles against Ischemia/Reoxygenation Are Mediated by the Activation of the Ca2+ Signaling System of Astrocytes and Reactive Astrogliosis
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    Host parameters and mode of infection influence outcome in SARS-CoV-2-infected hamsters
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    Clinical Response to Anti-CD47 Immunotherapy Is Associated with Rapid Reduction of Exhausted Bystander CD4+ BTLA+ T Cells in Tumor Microenvironment of Mycosis Fungoides
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    Long-term effect of full-body pulsed electromagnetic field and exercise protocol in the treatment of men with osteopenia or osteoporosis: A randomized placebo-controlled trial
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  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Evaluation of a 5-HT2B receptor agonist in a murine model of amyotrophic lateral sclerosis
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  168. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Sec3 exocyst component knockdown inhibits axonal formation and cortical neuronal migration during brain cortex development
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon mRNA vaccination
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  170. www.cell.com www.cell.com
    MYC assembles and stimulates topoisomerases 1 and 2 in a “topoisome”
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  171. www.science.org www.science.org
    A biomarker-authenticated model of schizophrenia implicating NPTX2 loss of function
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  174. www.sciencedirect.com www.sciencedirect.com
    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    Anti-recombination function of MutSα restricts telomere extension by ALT-associated homology-directed repair
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  176. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Input and output organization of the mesodiencephalic junction for cerebro-cerebellar communication
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    Coordinated repression of pro-differentiation genes via P-bodies and transcription maintains Drosophila intestinal stem cell identity
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    Functional consequences of postnatal interventions in a mouse model of Fragile X syndrome
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    The mesoscale organization of syntaxin 1A and SNAP25 is determined by SNARE–SNARE interactions
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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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  182. www.mdpi.com www.mdpi.com
    Andrographolide Attenuates Established Pulmonary Hypertension via Rescue of Vascular Remodeling
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    A glial ClC Cl− channel mediates nose touch responses in C. elegans
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Homeostatic scaling is driven by a translation-dependent degradation axis that recruits miRISC remodeling
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FMRP and MOV10 regulate Dicer1 expression and dendrite development
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    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
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    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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    Radium 223 treatment increase immune checkpoint expression in extracellular vesicles from the metastatic prostate cancer bone microenvironment
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    The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions
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    Chronic adrenergic stress contributes to metabolic dysfunction and an exhausted phenotype in T cells in the tumor microenvironment
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    A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
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  192. www.sciencedirect.com www.sciencedirect.com
    Immunofluorescence microscopy-based detection of ssDNA foci by BrdU in mammalian cells
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    An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers
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    Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria
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  195. elifesciences.org elifesciences.org
    Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
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  196. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
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  197. academic.oup.com academic.oup.com
    Neuronal KGB-1 JNK MAPK signaling regulates the dauer developmental decision in response to environmental stress in Caenorhabditis elegans
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  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei
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