10,000 Matching Annotations
  1. Dec 2021
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    In vivo efficacy of tesevatinib in patient-derived xenograft glioblastoma models may be limited by tissue binding and compensatory signaling
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1158/1535-7163.MCT-20-0640

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172524/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeted therapy to β3 integrin reduces chemoresistance in breast cancer bone metastases
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    1. scibot 02 Dec 2021
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      DOI: 10.1158/1535-7163.MCT-20-0931

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    ncbi.nlm.nih.gov/pmc/articles/PMC8442608/
  4. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Radium 223 treatment increase immune checkpoint expression in extracellular vesicles from the metastatic prostate cancer bone microenvironment
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1158/1078-0432.CCR-20-4790

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172463/
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The anti-HER3 monoclonal antibody seribantumab effectively inhibits growth of patient-derived and isogenic cell line and xenograft models with oncogenic NRG1 fusions
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    1. scibot 02 Dec 2021
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      DOI: 10.1158/1078-0432.CCR-20-3605

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    ncbi.nlm.nih.gov/pmc/articles/PMC8172458/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic adrenergic stress contributes to metabolic dysfunction and an exhausted phenotype in T cells in the tumor microenvironment
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1158/2326-6066.CIR-20-0445

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    ncbi.nlm.nih.gov/pmc/articles/PMC8355045/
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1016/j.isci.2021.103349

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    ncbi.nlm.nih.gov/pmc/articles/PMC8603209/
  8. www.sciencedirect.com www.sciencedirect.com
    Immunofluorescence microscopy-based detection of ssDNA foci by BrdU in mammalian cells
    1
    1. scibot 02 Dec 2021
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      DOI: 10.1016/j.xpro.2021.100978

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    sciencedirect.com/science/article/pii/S2666166721006845
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    An avian embryo patient-derived xenograft model for preclinical studies of human breast cancers
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.isci.2021.103423

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608609/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.72116

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    ncbi.nlm.nih.gov/pmc/articles/PMC8610492/
  11. elifesciences.org elifesciences.org
    Selective sorting of microRNAs into exosomes by phase-separated YBX1 condensates
    1
    1. scibot 01 Dec 2021
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      DOI: 10.7554/eLife.71982

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    elifesciences.org/articles/71982
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.ebiom.2021.103712

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    ncbi.nlm.nih.gov/pmc/articles/PMC8613501/
  13. academic.oup.com academic.oup.com
    Neuronal KGB-1 JNK MAPK signaling regulates the dauer developmental decision in response to environmental stress in Caenorhabditis elegans
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1093/genetics/iyab186

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    academic.oup.com/genetics/advance-article/doi/10.1093/genetics/iyab186/6415830
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mucus threads from surface goblet cells clear particles from the airways
    1
    1. scibot 01 Dec 2021
      RRID:SCR_002798

      DOI: 10.1186/s12931-021-01898-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC8620232/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Whole-brain connectivity atlas of glutamatergic and GABAergic neurons in the mouse dorsal and median raphe nuclei
    1
    1. scibot 01 Dec 2021
      RRID:SCR_002798

      DOI: 10.7554/eLife.65502

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    ncbi.nlm.nih.gov/pmc/articles/PMC8626088/
  16. www.sciencedirect.com www.sciencedirect.com
    Piezo1 and Piezo2 foster mechanical gating of K2P channels
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110070

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    sciencedirect.com/science/article/pii/S2211124721015564
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    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110064

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    sciencedirect.com/science/article/pii/S2211124721015503
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    Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110062

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    sciencedirect.com/science/article/pii/S2211124721015485
  19. www.sciencedirect.com www.sciencedirect.com
    Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
    1
    1. scibot 01 Dec 2021
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      DOI: 10.1016/j.celrep.2021.110061

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    sciencedirect.com/science/article/pii/S2211124721015473
  20. www.sciencedirect.com www.sciencedirect.com
    Opto-vTrap, an optogenetic trap for reversible inhibition of vesicular release, synaptic transmission, and behavior
    1
    1. scibot 01 Dec 2021
      RRID:SCR_002798

      DOI: 10.1016/j.neuron.2021.11.003

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    sciencedirect.com/science/article/pii/S0896627321008965
  21. Nov 2021
  22. www.sciencedirect.com www.sciencedirect.com
    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
    1
    1. scibot 30 Nov 2021
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      DOI: 10.1016/j.immuni.2021.11.002

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    sciencedirect.com/science/article/pii/S1074761321004933
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p190RhoGAP Filters Competing Signals to Resolve Axon Guidance Conflicts
    1
    1. scibot 29 Nov 2021
      RRID:SCR_002798

      DOI: 10.1016/j.neuron.2019.02.034

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    ncbi.nlm.nih.gov/pmc/articles/PMC8608148/
  24. f1000research.com f1000research.com
    A Randomized Control Trial to Test Effect of Cash Incentives and Training on Active Casefinding for Tuberculosis among Community Health Workers in Nigeria
    1
    1. scibot 25 Nov 2021
      RRID:SCR_002798

      DOI: 10.12688/f1000research.53822.1

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    f1000research.com/articles/10-1154
  25. www.sciencedirect.com www.sciencedirect.com
    Flight-induced compass representation in the monarch butterfly heading network
    1
    1. scibot 25 Nov 2021
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      DOI: 10.1016/j.cub.2021.11.009

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    sciencedirect.com/science/article/pii/S0960982221015335
  26. www.sciencedirect.com www.sciencedirect.com
    PNET2 is a component of the plant nuclear lamina and is required for proper genome organization and activity
    1
    1. scibot 25 Nov 2021
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      DOI: 10.1016/j.devcel.2021.11.002

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    sciencedirect.com/science/article/pii/S153458072100887X
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MET Receptor Tyrosine Kinase Regulates Lifespan Ultrasonic Vocalization and Vagal Motor Neuron Development
    1
    1. scibot 24 Nov 2021
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      DOI: 10.3389/fnins.2021.768577

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    ncbi.nlm.nih.gov/pmc/articles/PMC8600253/
  28. elifesciences.org elifesciences.org
    Localization of KRAS downstream target ARL4C to invasive pseudopods accelerates pancreatic cancer cell invasion
    1
    1. scibot 24 Nov 2021
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      DOI: 10.7554/eLife.66721

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    elifesciences.org/articles/66721
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation
    1
    1. scibot 24 Nov 2021
      RRID:SCR_015807

      DOI: 10.7554/eLife.64695

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    ncbi.nlm.nih.gov/pmc/articles/PMC8601662/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of the COVID-19 pandemic in the Portuguese population: Consumption of alcohol, stimulant drinks, illegal substances, and pharmaceuticals
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1371/journal.pone.0260322

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    ncbi.nlm.nih.gov/pmc/articles/PMC8604309/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fusobacterium nucleatum drives a pro-inflammatory intestinal microenvironment through metabolite receptor-dependent modulation of IL-17 expression
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1080/19490976.2021.1987780

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    ncbi.nlm.nih.gov/pmc/articles/PMC8604392/
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A large panel of chicken cells are invaded in vivo by Salmonella Typhimurium even when depleted of all known invasion factors
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1098/rsob.210117

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    ncbi.nlm.nih.gov/pmc/articles/PMC8596019/
  33. clincancerres.aacrjournals.org clincancerres.aacrjournals.org
    Molecular Subtyping Combined with Biological Pathway Analyses to Study Regorafenib Response in Clinically Relevant Mouse Models of Colorectal Cancer
    1
    1. scibot 24 Nov 2021
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      DOI: 10.1158/1078-0432.CCR-21-0818

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    clincancerres.aacrjournals.org/content/27/21/5979
  34. mct.aacrjournals.org mct.aacrjournals.org
    Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models
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    1. scibot 24 Nov 2021
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      DOI: 10.1158/1535-7163.MCT-21-0470

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    mct.aacrjournals.org/content/20/11/2262
  35. mct.aacrjournals.org mct.aacrjournals.org
    SAGE1: a Potential Target Antigen for Lung Cancer T-Cell Immunotherapy
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    1. scibot 24 Nov 2021
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      DOI: 10.1158/1535-7163.MCT-21-0203

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    mct.aacrjournals.org/content/20/11/2302
  36. 52.53.155.43 52.53.155.43
    jn.00333.2021-html.html
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      DOI: 10.1152/jn.00333.2021

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    52.53.155.43/3c8e7091b8dfca4e90b5c0f43e8ad33298e0f766/jn.00333.2021-html.html
  37. 52.53.155.43 52.53.155.43
    ajplung.00450.2020-html.html
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      DOI: 10.1152/ajplung.00450.2020

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    52.53.155.43/75b46aa5da9ae4c66a5bb771febe805f4cde088f/ajplung.00450.2020-html.html
  38. 52.53.155.43 52.53.155.43
    ajpgi.00458.2020-html.html
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      DOI: 10.1152/ajpgi.00458.2020

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  39. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Phospholipase D and retromer promote recycling of TRPL ion channel via the endoplasmic reticulum
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    1. scibot 24 Nov 2021
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      DOI: 10.1111/tra.12824

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    onlinelibrary.wiley.com/doi/10.1111/tra.12824
  40. www.sciencedirect.com www.sciencedirect.com
    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110058

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    sciencedirect.com/science/article/pii/S2211124721015448
  41. www.sciencedirect.com www.sciencedirect.com
    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110056

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    sciencedirect.com/science/article/pii/S2211124721015424
  42. www.sciencedirect.com www.sciencedirect.com
    SUMO orchestrates multiple alternative DNA-protein crosslink repair pathways
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110034

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    sciencedirect.com/science/article/pii/S2211124721015163
  43. www.sciencedirect.com www.sciencedirect.com
    The asymmetric Pitx2 gene regulates gut muscular-lacteal development and protects against fatty liver disease
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    1. scibot 24 Nov 2021
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      DOI: 10.1016/j.celrep.2021.110030

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    Expression of glucose transporter-2 in murine retina: Evidence for glucose transport from horizontal cells to photoreceptor synapses
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    1-Hydroxypyrene mediates renal fibrosis through aryl hydrocarbon receptor signalling pathway
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    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    Novel protocol for the isolation of highly purified neonatal murine microglia and astrocytes
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    A highly conserved zebrafish IMPDH retinal isoform produces the majority of guanine and forms dynamic protein filaments in photoreceptor cells
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    Moderate blood alcohol and brain neurovulnerability: Selective depletion of calcium-independent PLA2, omega-3 docosahexaenoic acid and its synaptamide derivative as a potential harbinger of deficits in anti-inflammatory reserve
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    The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
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    Control of Arabidopsis shoot stem cell homeostasis by two antagonistic CLE peptide signalling pathways
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    LXR directly regulates glycosphingolipid synthesis and affects human CD4+ T cell function
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    A neuropeptidergic circuit gates selective escape behavior of Drosophila larvae
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    Beta RBD Boost Broadens Antibody-Mediated Protection Against SARS-CoV-2 Variants in Animal Models
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    The fission yeast FLCN/FNIP complex augments TORC1 repression or activation in response to amino acid (AA) availability
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    Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome
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    Vaccine targeting ANGPTL3 ameliorates dyslipidemia and associated diseases in mouse models of obese dyslipidemia and familial hypercholesterolemia
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    (R)‐Ketamine exerts antidepressant actions partly via conversion to (2R,6R)‐hydroxynorketamine, while causing adverse effects at sub‐anaesthetic doses
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    A single aromatic residue in sgp130Fc (olamkicept) allows the discrimination between interleukin-6 (IL-6) and IL-11 trans-signaling
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    Alternative splicing of NF-YA promotes prostate cancer aggressiveness and represents a new molecular marker for clinical stratification of patients
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    Alterations in Glycerolipid and Fatty Acid Metabolic Pathways in Alzheimer's Disease Identified by Urinary Metabolic Profiling: A Pilot Study
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    Fluoroquinolones Suppress TGF-β and PMA-Induced MMP-9 Production in Cancer Cells: Implications in Repurposing Quinolone Antibiotics for Cancer Treatment
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    Deletion of pancreas-specific miR-216a reduces beta-cell mass and inhibits pancreatic cancer progression in mice
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    MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    Sex-Specific Alterations in Inflammatory MicroRNAs in Mouse Brain and Bone Marrow CD11b+ Cells Following Traumatic Brain Injury
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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    AtpΘ is an inhibitor of F0F1 ATP synthase to arrest ATP hydrolysis during low-energy conditions in cyanobacteria
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    A Cell-Based Platform for the Investigation of Immunoproteasome Subunit β5i Expression and Biology of β5i-Containing Proteasomes
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    Maternal background alters the penetrance of growth phenotypes and sex-specific placental adaptation of offspring sired by alcohol-exposed males
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    Dysfunctional BTN3A together with deregulated immune checkpoints and type I/II IFN dictate defective interplay between pDCs and γδ T cells in melanoma patients, which impacts clinical outcomes
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    Prenatal interleukin 6 elevation increases glutamatergic synapse density and disrupts hippocampal connectivity in offspring
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    Temporal dynamics of persistent germinal centers and memory B cell differentiation following respiratory virus infection
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    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
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    The Aurora B gradient sustains kinetochore stability in anaphase
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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    Dietary nitrate supplementation prevents radiotherapy-induced xerostomia
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    Developmental emergence of two-stage nonlinear synaptic integration in cerebellar interneurons
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    The rates of stem cell division determine the cell cycle lengths of its lineage
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    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
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    Attention to time-of-day variability improves the reproducibility of gene expression patterns in multiple sclerosis
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    Reduced mitochondrial respiration in T cells of patients with major depressive disorder
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    Merkel cell polyomavirus T-antigens regulate DICER1 mRNA stability and translation through HSC70
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    Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease
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    Inhibition of neutral sphingomyelinase 2 reduces extracellular vesicle release from neurons, oligodendrocytes, and activated microglial cells following acute brain injury
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    Antibody-Drug Conjugate and Free Geldanamycin Combination Therapy Enhances Anti-Cancer Efficacy
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    Neocortex saves energy by reducing coding precision during food scarcity
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    Coronavirus induces diabetic macrophage-mediated inflammation via SETDB2
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    The Lon protease temporally restricts polar cell differentiation events during the Caulobacter cell cycle
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    Myopalladin knockout mice develop cardiac dilation and show a maladaptive response to mechanical pressure overload
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    Fascin limits Myosin activity within Drosophila border cells to control substrate stiffness and promote migration
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    NHE6 depletion corrects ApoE4-mediated synaptic impairments and reduces amyloid plaque load
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    Inheritance of pheromone profiles from aged D. melanogaster
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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    Pathogenic LRRK2 control of primary cilia and Hedgehog signaling in neurons and astrocytes of mouse brain
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    Fibrinogen αC-subregions critically contribute blood clot fibre growth, mechanical stability and resistance to fibrinolysis
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    Targeting EYA3 in Ewing Sarcoma Retards Tumor Growth and Angiogenesis
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    Auditory and Vestibular Efferents: Nicotine evoked efferent transmitter release onto immature cochlear inner hair cells
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    A single synonymous nucleotide change impacts the male-killing phenotype of prophage WO gene wmk
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    Intratumoral plasmid IL-12 expands CD8+ T cells and induces a CXCR3 gene signature in triple-negative breast tumors that sensitizes patients to anti-PD-1 therapy
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    Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy
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    Pyruvate Kinase M2 Mediates Glycolysis Contributes to Psoriasis by Promoting Keratinocyte Proliferation
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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined transcriptomic and lipidomic analysis of D-4F ameliorating bleomycin-induced pulmonary fibrosis
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    All-trans retinoic acid induces synaptopodin-dependent metaplasticity in mouse dentate granule cells
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    Polarized Dishevelled dissolution and reassembly drives embryonic axis specification in sea star oocytes
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    TGF-β orchestrates the phenotype and function of monocytic myeloid-derived suppressor cells in colorectal cancer
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    Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition
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    MK2 promotes Tfcp2l1 degradation via β-TrCP ubiquitin ligase to regulate mouse embryonic stem cell self-renewal
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    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
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    SENP1 in the retrosplenial agranular cortex regulates core autistic-like symptoms in mice
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    Patch-seq of mouse DRG neurons reveals candidate genes for specific mechanosensory functions
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  138. cancerci.biomedcentral.com cancerci.biomedcentral.com
    Quantitative phosphoproteomic analysis reveals chemoresistance-related proteins and signaling pathways induced by rhIL-6 in human osteosarcoma cells
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    Methanolic Fraction from Tamala (Diospyros montana Roxb.) Ameliorates Anxiety Like Behaviour via 5-HT2A Pathway in Rats
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  140. Oct 2021
  141. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Role of miR-185-5p as modulator of periostin synthesis and smooth muscle contraction in asthma
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      DOI: 10.1002/jcp.30620

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  142. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Faim knockout leads to gliosis and late-onset neurodegeneration of photoreceptors in the mouse retina
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      DOI: 10.1002/jnr.24978

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    Ultrastructure of ipsilateral and contralateral tectopulvinar projections in the mouse
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      DOI: 10.1002/cne.25264

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  144. onlinelibrary.wiley.com onlinelibrary.wiley.com
    N-myc downstream regulated family member 1 (NDRG1) is enriched in myelinating oligodendrocytes and impacts myelin degradation in response to demyelination
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      DOI: 10.1002/glia.24108

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    Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
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    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
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    Pan-ebolavirus protective therapy by two multifunctional human antibodies
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  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal ribosomes exhibit dynamic and context-dependent exchange of ribosomal proteins
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      DOI: 10.1038/s41467-021-26365-x

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  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zyxin Mediates Vascular Repair via Endothelial Migration Promoted by Forskolin in Mice
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  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Treadmill Exercise Attenuates Cerebral Ischemia–Reperfusion Injury by Promoting Activation of M2 Microglia via Upregulation of Interleukin-4
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  151. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Deep Learning to Decipher the Progression and Morphology of Axonal Degeneration
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      DOI: 10.3390/cells10102539

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  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dissecting VEGF-induced acute versus chronic vascular hyperpermeability: Essential roles of dimethylarginine dimethylaminohydrolase-1
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HES1 protein oscillations are necessary for neural stem cells to exit from quiescence
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  154. elifesciences.org elifesciences.org
    HIF1α stabilization in hypoxia is not oxidant-initiated
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      DOI: 10.7554/eLife.72873

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    Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction
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      DOI: 10.7554/eLife.68280

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  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stimulation of hypothalamic oxytocin neurons suppresses colorectal cancer progression in mice
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Safety and Efficacy of a Novel Centrifugal Pump and Driving Devices of the OASSIST ECMO System: A Preclinical Evaluation in the Ovine Model
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      DOI: 10.3389/fmed.2021.712205

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    Characterization and functional role of rapid- and slow-activating delayed rectifier K+ currents in atrioventricular node cells of guinea pigs
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      DOI: 10.1007/s00424-021-02617-z

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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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  160. www.embopress.org www.embopress.org
    Reprogramming of glucocorticoid receptor function by hypoxia
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      DOI: 10.15252/embr.202153083

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  161. insight.jci.org insight.jci.org
    Dual-isoform hUBE3A gene transfer improves behavioral and seizure outcomes in Angelman syndrome model mice
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      DOI: 10.1172/jci.insight.144712

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  162. www.sciencedirect.com www.sciencedirect.com
    RNF168 E3 ligase participates in ubiquitin signaling and recruitment of SLX4 during DNA crosslink repair
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    Munc13-1 is a Ca2+-phospholipid-dependent vesicle priming hub that shapes synaptic short-term plasticity and enables sustained neurotransmission
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      DOI: 10.1016/j.neuron.2021.09.054

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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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      DOI: 10.1016/j.celrep.2021.109899

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    Multilayer omics analysis reveals a non-classical retinoic acid signaling axis that regulates hematopoietic stem cell identity
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      DOI: 10.1016/j.stem.2021.10.002

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    Assessment of neurodegeneration and neuronal loss in aged 5XFAD mice
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      DOI: 10.1016/j.xpro.2021.100915

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    The PPARγ-dependent effect of flavonoid luteolin against damage induced by the chemotherapeutic irinotecan in human intestinal cells
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      DOI: 10.1016/j.cbi.2021.109712

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    MACF1 promotes osteoblastic cell migration by regulating MAP1B through the GSK3beta/TCF7 pathway
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    Expression dynamics of pregnane X receptor-controlled genes in 3D primary human hepatocyte spheroids
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      DOI: 10.1007/s00204-021-03177-y

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  170. www.nature.com www.nature.com
    Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood
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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRPM7 is critical for short-term synaptic depression by regulating synaptic vesicle endocytosis
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  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Peripherally restricted cannabinoid type 1 receptor (CB1R) antagonist, AM6545, potentiates stress-induced hypothalamic–pituitary–adrenal axis activation via a non-CB1R mechanism
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  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microglia and CD206+ border-associated mouse macrophages maintain their embryonic origin during Alzheimer’s disease
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    Myogenin controls via AKAP6 non-centrosomal microtubule-organizing center formation at the nuclear envelope
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    Experience-dependent weakening of callosal synaptic connections in the absence of postsynaptic FMRP
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    Functional Effects of Receptor-Binding Domain Mutations of SARS-CoV-2 B.1.351 and P.1 Variants
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    Glycogen accumulation and phase separation drives liver tumor initiation
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    Identification of deubiquitinase inhibitors via high-throughput screening using a fluorogenic ubiquitin-rhodamine assay
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    Characterization of six CaMKIIα variants found in patients with schizophrenia
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    Germacrone Attenuates Hepatic Stellate Cells Activation and Liver Fibrosis via Regulating Multiple Signaling Pathways
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      DOI: 10.3389/fphar.2021.745561

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    Tau reduction affects excitatory and inhibitory neurons differently, reduces excitation/inhibition ratios, and counteracts network hypersynchrony
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    Simultaneous analyses of clutch coupling and actin polymerization in dendritic spines of rodent hippocampal neurons during chemical LTP
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    Pan-cancer analysis of non-coding transcripts reveals the prognostic onco-lncRNA HOXA10-AS in gliomas
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    Targeting the IRE1α/XBP1 Endoplasmic Reticulum Stress Response Pathway in ARID1A-Mutant Ovarian Cancers
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      DOI: 10.1158/0008-5472.CAN-21-1545

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    ASTX029, a Novel Dual-mechanism ERK Inhibitor, Modulates Both the Phosphorylation and Catalytic Activity of ERK
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      DOI: 10.1158/1535-7163.MCT-20-0909

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    aacrjournals.org/mct/article/20/10/1757/665735/ASTX029-a-Novel-Dual-mechanism-ERK-Inhibitor
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      DOI: 10.1111/jth.15543

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    Synaptotagmin-11 inhibits spontaneous neurotransmission through vti1a
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      DOI: 10.1111/jnc.15523

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    Distinct Dose-dependent Effects of Methamphetamine on Real-time Dopamine Transmission in the Rat Nucleus Accumbens and Behaviors
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      DOI: 10.1111/jnc.15470

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      DOI: 10.1111/bph.15660

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      DOI: 10.1111/bph.15631

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      DOI: 10.1111/bph.15643

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    A Role for Translational Regulation by S6 Kinase and a Downstream Target in Inflammatory Pain
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      DOI: 10.1111/bph.15646

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    Characterization of a high throughput human stem cell cardiomyocyte assay to predict drug-induced changes in clinical electrocardiogram parameters
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    Hemispheric cortical atrophy and chronic microglial activation following mild focal ischemic stroke in adult male rats
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      DOI: 10.1002/jnr.24939

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    Plastin and spectrin cooperate to stabilize the actomyosin cortex during cytokinesis
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      DOI: 10.1016/j.cub.2021.09.055

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    Detection of surface forces by the cell-wall mechanosensor Wsc1 in yeast
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      DOI: 10.1016/j.devcel.2021.09.024

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    Preclinical Evaluation of [11C]YC-72-AB85 for In Vivo Visualization of Heat Shock Protein 90 in Brain and Cancer with Positron Emission Tomography
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      DOI: 10.1021/acschemneuro.1c00508

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