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449 Matching Annotations

May 2021
aacrjournals.org aacrjournals.org

A MyD88/IL-1R axis regulates PD-1 expression on tumor-associated macrophages and sustains their immunosuppressive function in melanoma

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1. scibot 10 May 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1158/0008-5472.CAN-20-3510
  
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aacrjournals.org/cancerres/article/81/9/2358/670580/A-MyD88-IL1R-Axis-Regulates-PD-1-Expression-on
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

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1. scibot 10 May 2021
  
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  DOI: 10.1111/bph.15457
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15457
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BMI1 Inhibition Eliminates Residual Cancer Stem Cells after PD1 Blockade and Activates Antitumor Immunity to Prevent Metastasis and Relapse

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1. scibot 09 May 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.stem.2020.06.022
  
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sciencedirect.com/science/article/pii/S1934590920302897
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Interferon-γ induces tumor resistance to anti-PD-1 immunotherapy by promoting YAP phase separation

1
1. scibot 08 May 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.molcel.2021.01.010
  
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sciencedirect.com/science/article/pii/S1097276521000101
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Eomes-Dependent Loss of the Co-activating Receptor CD226 Restrains CD8+ T Cell Anti-tumor Functions and Limits the Efficacy of Cancer Immunotherapy

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1. scibot 07 May 2021
  
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  DOI: 10.1016/j.immuni.2020.09.006
  
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sciencedirect.com/science/article/pii/S1074761320304003
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Aging-dependent mitochondrial dysfunction mediated by ceramide signaling inhibits antitumor T cell response

1
1. scibot 05 May 2021
  
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  DOI: 10.1016/j.celrep.2021.109076
  
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sciencedirect.com/science/article/pii/S2211124721004071
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Pharmacological Wnt ligand inhibition overcomes key tumor-mediated resistance pathways to anti-PD-1 immunotherapy

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1. scibot 05 May 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2021.109071
  
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ncbi.nlm.nih.gov/labs/pmc/articles/PMC8148423/
Apr 2021
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Metabolic-Pathway-Based Subtyping of Triple-Negative Breast Cancer Reveals Potential Therapeutic Targets

1
1. scibot 29 Apr 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cmet.2020.10.012
  
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sciencedirect.com/science/article/pii/S1550413120305453
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Sirt2 Inhibition Enhances Metabolic Fitness and Effector Functions of Tumor-Reactive T Cells

1
1. scibot 29 Apr 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cmet.2020.07.008
  
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sciencedirect.com/science/article/pii/S1550413120303661
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CD36-mediated ferroptosis dampens intratumoral CD8+ T cell effector function and impairs their antitumor ability

1
1. scibot 26 Apr 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cmet.2021.02.015
  
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sciencedirect.com/science/article/pii/S1550413121000711
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Cytotoxic lymphocytes target characteristic biophysical vulnerabilities in cancer

1
1. scibot 06 Apr 2021
  
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  InVivoPlus anti-mouse PD-1 (CD279)
  
  DOI: 10.1016/j.immuni.2021.02.020
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @Naa003
  
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  RRID:AB_10949053 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1074761321000868
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

PD-1 suppresses the maintenance of cell couples between cytotoxic T cells and target tumor cells within the tumor

1
1. scibot 17 Mar 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1126/scisignal.aau4518
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @evieth
  
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  RRID:AB_10949053 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7784968/
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Integrin αvβ6–TGFβ–SOX4 Pathway Drives Immune Evasion in Triple-Negative Breast Cancer

1
1. scibot 08 Mar 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2020.12.001
  
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sciencedirect.com/science/article/pii/S1535610820306085
Feb 2021
insight.jci.org insight.jci.org

Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

1
1. scibot 26 Feb 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1172/jci.insight.134386
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
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insight.jci.org/articles/view/134386
Jan 2021
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Targeting Phosphatidylserine Enhances the Anti-tumor Response to Tumor-Directed Radiation Therapy in a Preclinical Model of Melanoma

1
1. scibot 21 Jan 2021
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2020.108620
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720316090
Sep 2020
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Myosin II Reactivation and Cytoskeletal Remodeling as a Hallmark and a Vulnerability in Melanoma Therapy Resistance

1
1. scibot 23 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2019.12.003
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1535610819305732
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Dendritic Cell Paucity Leads to Dysfunctional Immune Surveillance in Pancreatic Cancer

1
1. scibot 23 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2020.02.008
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S1535610820300970
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FOXD3 Regulates VISTA Expression in Melanoma

1
1. scibot 23 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.12.036
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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  RRID:AB_10949053 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124719316936
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CXCR1 and CXCR2 Chemokine Receptor Agonists Produced by Tumors Induce Neutrophil Extracellular Traps that Interfere with Immune Cytotoxicity

1
1. scibot 14 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.immuni.2020.03.001
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_10949053
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sciencedirect.com/science/article/pii/S1074761320300893
insight.jci.org insight.jci.org

Profiling of patients with glioma reveals the dominant immunosuppressive axis is refractory to immune function restoration

1
1. scibot 10 Sep 2020
  
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  RRID: AB_10949053
  
  DOI: 10.1172/jci.insight.134386
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @evieth
  
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insight.jci.org/articles/view/134386
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Remodeling of Metastatic Vasculature Reduces Lung Colonization and Sensitizes Overt Metastases to Immunotherapy

1
1. scibot 10 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.12.013
  
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  RRIDCUR:Validated RRID:AB_10949053
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sciencedirect.com/science/article/pii/S2211124719316626
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ADORA1 Inhibition Promotes Tumor Immune Evasion by Regulating the ATF3-PD-L1 Axis

1
1. scibot 07 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2020.02.006
  
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sciencedirect.com/science/article/pii/S1535610820300957
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Cathepsin S Regulates Antigen Processing and T Cell Activity in Non-Hodgkin Lymphoma

1
1. scibot 06 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2020.03.016
  
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  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_10949053
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sciencedirect.com/science/article/pii/S1535610820301562
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Blockade of the Phagocytic Receptor MerTK on Tumor-Associated Macrophages Enhances P2X7R-Dependent STING Activation by Tumor-Derived cGAMP

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1. scibot 05 Sep 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.immuni.2020.01.014
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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sciencedirect.com/science/article/pii/S107476132030042X
Jan 2020
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Clonally Expanded T Cells Reveal Immunogenicity of Rhabdoid Tumors

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2019.10.008
  
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  RRID:AB_10949053 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304829
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B Cells and T Follicular Helper Cells Mediate Response to Checkpoint Inhibitors in High Mutation Burden Mouse Models of Breast Cancer

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cell.2019.10.028
  
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sciencedirect.com/science/article/pii/S009286741931178X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Pulsatile MEK Inhibition Improves Anti-tumor Immunity and T Cell Function in Murine Kras Mutant Lung Cancer

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.03.066
  
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  Curator: @evieth
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6719696/
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Pro-Survival Lipid Sphingosine-1-Phosphate Metabolically Programs T Cells to Limit Anti-tumor Activity

1
1. scibot 13 Jan 2020
  
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  RRID:RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.07.044
  
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sciencedirect.com/science/article/pii/S2211124719309416
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PD-L1:CD80 Cis-Heterodimer Triggers the Co-stimulatory Receptor CD28 While Repressing the Inhibitory PD-1 and CTLA-4 Pathways

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.immuni.2019.11.003
  
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  RRID:AB_10949053 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761319304613
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Opposing Functions of Interferon Coordinate Adaptive and Innate Immune Responses to Cancer Immune Checkpoint Blockade

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cell.2019.07.019
  
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  RRID:AB_10949053 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867419307846
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The Polycomb Repressor Complex 1 Drives Double-Negative Prostate Cancer Metastasis by Coordinating Stemness and Immune Suppression

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2019.06.009
  
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sciencedirect.com/science/article/pii/S1535610819303009
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Differences in Tumor Microenvironment Dictate T Helper Lineage Polarization and Response to Immune Checkpoint Therapy

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.cell.2019.10.029
  
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sciencedirect.com/science/article/pii/S0092867419311791
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Small-Molecule MYC Inhibitors Suppress Tumor Growth and Enhance Immunotherapy

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1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2019.10.001
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
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  RRID:AB_10949053 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610819304398
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Activation of Mevalonate Pathway via LKB1 Is Essential for Stability of Treg Cells

1
1. scibot 13 Jan 2020
  
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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.05.020
  
  Resource: (Bio X Cell Cat# BE0146, RRID:AB_10949053)
  
  Curator: @ethanbadger
  
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Blocking Antibodies Targeting the CD39/CD73 Immunosuppressive Pathway Unleash Immune Responses in Combination Cancer Therapies

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  RRID:AB_10949053
  
  DOI: 10.1016/j.celrep.2019.04.091
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.021
  
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Targeting TMEM176B Enhances Antitumor Immunity and Augments the Efficacy of Immune Checkpoint Blockers by Unleashing Inflammasome Activation

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  RRID:AB_10949053
  
  DOI: 10.1016/j.ccell.2019.04.003
  
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Urea Cycle Dysregulation Generates Clinically Relevant Genomic and Biochemical Signatures

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IKZF1 Enhances Immune Infiltrate Recruitment in Solid Tumors and Susceptibility to Immunotherapy

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Reactive Neutrophil Responses Dependent on the Receptor Tyrosine Kinase c-MET Limit Cancer Immunotherapy

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Non-conventional Inhibitory CD4+Foxp3−PD-1hi T Cells as a Biomarker of Immune Checkpoint Blockade Activity

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Synergy between the KEAP1/NRF2 and PI3K Pathways Drives Non-Small-Cell Lung Cancer with an Altered Immune Microenvironment

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Paracrine Wnt5a-β-Catenin Signaling Triggers a Metabolic Program that Drives Dendritic Cell Tolerization

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TIM-3 Regulates CD103+ Dendritic Cell Function and Response to Chemotherapy in Breast Cancer

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Antibody Tumor Targeting Is Enhanced by CD27 Agonists through Myeloid Recruitment

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Epigenetic Therapy Ties MYC Depletion to Reversing Immune Evasion and Treating Lung Cancer

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Nov 2017
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Macrophage Polarization Contributes to Glioblastoma Eradication by Combination Immunovirotherapy and Immune Checkpoint Blockade

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1. scibot 08 Nov 2017
  
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Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade

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1. scibot 08 Nov 2017
  
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  Anti-PD-1 (clone RMP1-14)BioXcellCat# BE0146
  
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Systemic Immunity Is Required for Effective Cancer Immunotherapy

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1. scibot 08 Nov 2017
  
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