1,257 Matching Annotations
  1. May 2022
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective inhibition reveals the regulatory function of DYRK2 in protein synthesis and calcium entry
    1
    1. scibot 21 May 2022
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      DOI: 10.7554/eLife.77696

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    ncbi.nlm.nih.gov/pmc/articles/PMC9113749/
  3. www.sciencedirect.com www.sciencedirect.com
    Sexually dimorphic RNA helicases DDX3X and DDX3Y differentially regulate RNA metabolism through phase separation
    1
    1. scibot 19 May 2022
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      DOI: 10.1016/j.molcel.2022.04.022

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    sciencedirect.com/science/article/pii/S1097276522003859
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    Septin 9 and phosphoinositides regulate lysosome localization and their association with lipid droplets
    1
    1. scibot 13 May 2022
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      DOI: 10.1016/j.isci.2022.104288

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    sciencedirect.com/science/article/pii/S2589004222005582
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Interaction Between the Oncogenic Kinase NEK2 and Sam68 Promotes a Splicing Program Involved in Migration and Invasion in Triple-Negative Breast Cancer
    1
    1. scibot 11 May 2022
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      DOI: 10.3389/fonc.2022.880654

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    ncbi.nlm.nih.gov/pmc/articles/PMC9068942/
  6. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
    1
    1. scibot 03 May 2022
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      DOI: 10.1158/2159-8290.CD-20-1793

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  7. Apr 2022
  8. www.sciencedirect.com www.sciencedirect.com
    circMbl functions in cis and in trans to regulate gene expression and physiology in a tissue-specific fashion
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.celrep.2022.110740

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    sciencedirect.com/science/article/pii/S2211124722005010
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    Disrupting the HDAC6-ubiquitin interaction impairs infection by influenza and Zika virus and cellular stress pathways
    1
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      DOI: 10.1016/j.celrep.2022.110736

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    sciencedirect.com/science/article/pii/S2211124722004971
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    Cytoplasmic PARP1 links the genome instability to the inhibition of antiviral immunity through PARylating cGAS
    1
    1. scibot 27 Apr 2022
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      DOI: 10.1016/j.molcel.2022.03.034

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    sciencedirect.com/science/article/pii/S1097276522002908
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    Cellular signals converge at the NOX2-SHP-2 axis to induce reductive carboxylation in cancer cells
    1
    1. scibot 21 Apr 2022
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      DOI: 10.1016/j.chembiol.2022.03.010

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    sciencedirect.com/science/article/pii/S2451945622001271
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Stem cell factor SOX2 confers ferroptosis resistance in lung cancer via upregulation of SLC7A11
    1
    1. scibot 16 Apr 2022
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      DOI: 10.1158/0008-5472.CAN-21-0567

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    ncbi.nlm.nih.gov/pmc/articles/PMC8530936/
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    Reciprocal regulation of phosphatidylcholine synthesis and H3K36 methylation programs metabolic adaptation
    1
    1. scibot 15 Apr 2022
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    sciencedirect.com/science/article/pii/S2211124722004247
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    The CDC48 complex mediates ubiquitin-dependent degradation of intra-chloroplast proteins in plants
    1
    1. scibot 14 Apr 2022
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    sciencedirect.com/science/article/pii/S2211124722004168
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    Yeast cell death pathway requiring AP-3 vesicle trafficking leads to vacuole/lysosome membrane permeabilization
    1
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      DOI: 10.1016/j.celrep.2022.110647

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    sciencedirect.com/science/article/pii/S2211124722003990
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    Functional coupling of TRPM2 and extrasynaptic NMDARs exacerbates excitotoxicity in ischemic brain injury
    1
    1. scibot 14 Apr 2022
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      DOI: 10.1016/j.neuron.2022.03.021

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    sciencedirect.com/science/article/pii/S0896627322002574
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    Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
    1
    1. scibot 09 Apr 2022
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      DOI: 10.1016/j.immuni.2022.03.009

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    sciencedirect.com/science/article/pii/S1074761322001327
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
    1
    1. scibot 08 Apr 2022
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      DOI: 10.1158/1541-7786.MCR-21-0374

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recognition of discrete export signals in early flagellar subunits during bacterial type III secretion
    1
    1. scibot 07 Apr 2022
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      DOI: 10.7554/eLife.66264

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    ncbi.nlm.nih.gov/pmc/articles/PMC8983047/
  20. aacrjournals.org aacrjournals.org
    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
    1
    1. scibot 05 Apr 2022
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      DOI: 10.1158/2159-8290.CD-21-0692

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    aacrjournals.org/cancerdiscovery/article/12/4/1106/689604/Subversion-of-Serotonin-Receptor-Signaling-in
  21. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 05 Apr 2022
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      DOI: 10.1111/bph.15763

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763
  22. www.nature.com www.nature.com
    Recycling of autophagosomal components from autolysosomes by the recycler complex
    1
    1. scibot 01 Apr 2022
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      DOI: 10.1038/s41556-022-00861-8

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    nature.com/articles/s41556-022-00861-8
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional Assessment of Calcium-Sensing Receptor Variants Confirms Familial Hypocalciuric Hypercalcaemia
    1
    1. scibot 01 Apr 2022
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      DOI: 10.1210/jendso/bvac025

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    ncbi.nlm.nih.gov/pmc/articles/PMC8962451/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MLL5 is involved in retinal photoreceptor maturation through facilitating CRX-mediated photoreceptor gene transactivation
    1
    1. scibot 01 Apr 2022
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      DOI: 10.1016/j.isci.2022.104058

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    ncbi.nlm.nih.gov/pmc/articles/PMC8961232/
  25. Mar 2022
  26. www.sciencedirect.com www.sciencedirect.com
    Kinase domain autophosphorylation rewires the activity and substrate specificity of CK1 enzymes
    1
    1. scibot 30 Mar 2022
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      DOI: 10.1016/j.molcel.2022.03.005

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    sciencedirect.com/science/article/pii/S1097276522002143
  27. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms
    1
    1. scibot 26 Mar 2022
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      DOI: 10.1111/jnc.14666

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    onlinelibrary.wiley.com/doi/10.1111/jnc.14666
  28. onlinelibrary.wiley.com onlinelibrary.wiley.com
    The PTN-PTPRZ signal activates the AFAP1L2-dependent PI3K-AKT pathway for oligodendrocyte differentiation: Targeted inactivation of PTPRZ activity in mice
    1
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      DOI: 10.1002/glia.23583

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    onlinelibrary.wiley.com/doi/10.1002/glia.23583
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Silencing of Ago-2 Interacting Protein SERBP1 Relieves KCC2 Repression by miR-92 in Neurons
    1
    1. scibot 26 Mar 2022
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      DOI: 10.3390/cells11061052

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    ncbi.nlm.nih.gov/pmc/articles/PMC8947033/
  30. www.sciencedirect.com www.sciencedirect.com
    The XRN1-regulated RNA helicase activity of YTHDC2 ensures mouse fertility independently of m6A recognition
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    1. scibot 20 Mar 2022
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      DOI: 10.1016/j.molcel.2022.02.034

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    sciencedirect.com/science/article/pii/S1097276522002088
  31. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    PTENα regulates endocytosis and modulates olfactory function
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    1. scibot 19 Mar 2022
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      DOI: 10.1096/fj.201900588RR

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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.201900588RR
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Division of Labor between YAP and TAZ in Non–Small Cell Lung Cancer
    1
    1. scibot 17 Mar 2022
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      DOI: 10.1158/0008-5472.CAN-20-0125

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    ncbi.nlm.nih.gov/pmc/articles/PMC8916161/
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    Delicate regulation of IL-1β-mediated inflammation by cyclophilin A
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      DOI: 10.1016/j.celrep.2022.110513

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    sciencedirect.com/science/article/pii/S2211124722002492
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    Methylene-bridge tryptophan fatty acylation regulates PI3K-AKT signaling and glucose uptake
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      DOI: 10.1016/j.celrep.2022.110509

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    sciencedirect.com/science/article/pii/S2211124722002455
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    Mechanistic convergence of the TIGIT and PD-1 inhibitory pathways necessitates co-blockade to optimize anti-tumor CD8+ T cell responses
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      DOI: 10.1016/j.immuni.2022.02.005

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    sciencedirect.com/science/article/pii/S1074761322000851
  36. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Crosstalk between ERK and MRTF-A signaling regulates TGFβ1-induced epithelial-mesenchymal transition
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      DOI: 10.1002/jcp.30705

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    onlinelibrary.wiley.com/doi/10.1002/jcp.30705
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The NDNF-like factor Nord is a Hedgehog-induced extracellular BMP modulator that regulates Drosophila wing patterning and growth
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      DOI: 10.7554/eLife.73357

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    ncbi.nlm.nih.gov/pmc/articles/PMC8856659/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Maelstrom functions in the production of Siwi-piRISC capable of regulating transposons in Bombyx germ cells
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      DOI: 10.1016/j.isci.2022.103914

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    ncbi.nlm.nih.gov/pmc/articles/PMC8881725/
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    Itaconate and itaconate derivatives target JAK1 to suppress alternative activation of macrophages
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    sciencedirect.com/science/article/pii/S1550413122000468
  40. asbmr.onlinelibrary.wiley.com asbmr.onlinelibrary.wiley.com
    Transcription factor Hhex negatively regulates osteoclast differentiation by controlling cyclin-dependent kinase inhibitors
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      DOI: 10.1002/jbm4.10608

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    asbmr.onlinelibrary.wiley.com/doi/10.1002/jbm4.10608
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    Resurfaced ZIKV EDIII nanoparticle immunogens elicit neutralizing and protective responses in vivo
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      DOI: 10.1016/j.chembiol.2022.02.004

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    sciencedirect.com/science/article/pii/S245194562200085X
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    SARM1 IS A MULTI-FUNCTIONAL NAD(P)ASE WITH PROMINENT BASE EXCHANGE ACTIVITY, ALL REGULATED BY MULTIPLE PHYSIOLOGICALLY-RELEVANT NAD METABOLITES
    1
    1. scibot 02 Mar 2022
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      DOI: 10.1016/j.isci.2022.103812

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    sciencedirect.com/science/article/pii/S2589004222000827
  43. Feb 2022
  44. www.sciencedirect.com www.sciencedirect.com
    SENP2 suppresses browning of white adipose tissues by de-conjugating SUMO from C/EBPβ
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    Gene replacement strategies validate the use of functional tags on centromeric chromatin and invalidate an essential role for CENP-AK124ub
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    Identification of long-lived proteins in the mitochondria reveals increased stability of the electron transport chain
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    Mechanistic Insights into COVID-19 by Global Analysis of the SARS-CoV-2 3CLpro Substrate Degradome
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    Enhancer recruitment of transcription repressors RUNX1 and TLE3 by mis-expressed FOXC1 blocks differentiation in acute myeloid leukemia
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