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549 Matching Annotations

Jul 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Soluble Fas ligand drives autoantibody-induced arthritis by binding to DR5/TRAIL-R2

1
1. scibot 09 Jul 2021
  
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  RRID:AB_331284
  
  DOI: 10.7554/eLife.48840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8257255/
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Systematic analysis of SARS-CoV-2 infection of an ACE2-negative human airway cell

1
1. scibot 07 Jul 2021
  
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  DOI: 10.1016/j.celrep.2021.109364
  
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sciencedirect.com/science/article/pii/S2211124721007622
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Spinal interleukin-1β induces mechanical spinal hyperexcitability in rats: interactions and redundancies with TNF and IL-6

1
1. scibot 02 Jul 2021
  
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  DOI: 10.1111/jnc.15438
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15438
Jun 2021
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CX3CL1–CX3CR1 signalling deficiency exacerbates obesity-induced inflammation and insulin resistance in male mice

1
1. scibot 29 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.1210/endocr/bqab064
  
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academic.oup.com/endo/article/162/6/bqab064/6188411
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Multiple pathways of toxicity induced by C9orf72 dipeptide repeat aggregates and G4C2 RNA in a cellular model

1
1. scibot 29 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.7554/eLife.62718
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8221807/
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Riok3 inhibits the antiviral immune response by facilitating TRIM40-mediated RIG-I and MDA5 degradation

1
1. scibot 23 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.celrep.2021.109272
  
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sciencedirect.com/science/article/pii/S2211124721006392
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OTULIN allies with LUBAC to govern angiogenesis by editing ALK1 linear polyubiquitin

1
1. scibot 22 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.molcel.2021.05.031
  
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sciencedirect.com/science/article/pii/S1097276521004445
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Canonical NF-κB signaling maintains corneal epithelial integrity and prevents corneal aging via retinoic acid

1
1. scibot 17 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.7554/eLife.67315
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8192125/
www.embopress.org www.embopress.org

Gut microbiota-CRAMP axis shapes intestinal barrier function and immune responses in dietary gluten-induced enteropathy

1
1. scibot 17 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.15252/emmm.202114059
  
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embopress.org/doi/abs/10.15252/emmm.202114059
www.hindawi.com www.hindawi.com

HO-1/CO Maintains Intestinal Barrier Integrity through NF-κB/MLCK Pathway in Intestinal HO-1-/- Mice

1
1. scibot 12 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.1155/2021/6620873
  
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hindawi.com/journals/omcl/2021/6620873/
elifesciences.org elifesciences.org

Tendon and motor phenotypes in the Crtap-/- mouse model of recessive osteogenesis imperfecta

1
1. scibot 11 Jun 2021
  
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  RRID:AB_331284
  
  DOI: 10.7554/eLife.63488
  
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elifesciences.org/articles/63488
May 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

hTERT-immortalized gingival fibroblasts respond to cytokines but fail to mimic primary cell responses to Porphyromonas gingivalis

1
1. scibot 27 May 2021
  
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  #3033
  
  DOI: 10.1038/s41598-021-90037-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8144196/
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Stk24 protects against obesity-associated metabolic disorders by disrupting the NLRP3 inflammasome

1
1. scibot 26 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.celrep.2021.109161
  
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sciencedirect.com/science/article/pii/S2211124721005039
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The zinc finger protein Miz1 suppresses liver tumorigenesis by restricting hepatocyte-driven macrophage activation and inflammation

1
1. scibot 26 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.immuni.2021.04.027
  
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sciencedirect.com/science/article/pii/S1074761321001898
onlinelibrary.wiley.com onlinelibrary.wiley.com

Artemisinin inhibits TLR4 signaling by targeting co-receptor MD2 in microglial BV-2 cells and prevents lipopolysaccharide-induced blood–brain barrier leakage in mice

1
1. scibot 20 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1111/jnc.15302
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15302
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

A novel oncotherapy strategy: Direct thrombin inhibitors suppress progression, dissemination and spontaneous metastasis in non-small cell lung cancer

1
1. scibot 20 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1111/bph.15384
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15384
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RANK links senescence to stemness in the mammary epithelia, delaying tumor onset but increasing tumor aggressiveness

1
1. scibot 18 May 2021
  
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  Phospho-NF-κB p65 (Ser536) (clone 93H1)
  
  DOI: 10.1016/j.devcel.2021.04.022
  
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sciencedirect.com/science/article/pii/S1534580721003609
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Neutrophil elastase selectively kills cancer cells and attenuates tumorigenesis

1
1. scibot 10 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.cell.2021.04.016
  
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sciencedirect.com/science/article/pii/S0092867421004955
www.spandidos-publications.com www.spandidos-publications.com

Treatment with a probiotic combination reduces abdominal adhesion in rats by decreasing intestinal inflammation and restoring microbial composition

1
1. scibot 07 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.3892/or.2020.7463
  
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spandidos-publications.com/10.3892/or.2020.7463
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Polymer-ritonavir derivate nanomedicine with pH-sensitive activation possesses potent anti-tumor activity in vivo via inhibition of proteasome and STAT3 signaling

1
1. scibot 07 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.jconrel.2021.03.015
  
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sciencedirect.com/science/article/pii/S0168365921001267
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Mechanical competition triggered by innate immune signaling drives the collective extrusion of bacterially infected epithelial cells

1
1. scibot 06 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.devcel.2021.01.012
  
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sciencedirect.com/science/article/pii/S1534580721000708
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N6-Adenosine Methylation of Socs1 mRNA Is Required to Sustain the Negative Feedback Control of Macrophage Activation

1
1. scibot 05 May 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.devcel.2020.10.023
  
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sciencedirect.com/science/article/pii/S1534580720308431
faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com

Elevated GFAP isoform expression promotes protein aggregation and compromises astrocyte function

1
1. scibot 04 May 2021
  
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  AB_331284
  
  DOI: 10.1096/fj.202100087R
  
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faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202100087R
Apr 2021
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TANK-Binding Kinase 1 Regulates the Localization of Acyl-CoA Synthetase ACSL1 to Control Hepatic Fatty Acid Oxidation

1
1. scibot 29 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.cmet.2020.10.010
  
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sciencedirect.com/science/article/pii/S155041312030543X
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The Major Pre- and Postmenopausal Estrogens Play Opposing Roles in Obesity-Driven Mammary Inflammation and Breast Cancer Development

1
1. scibot 29 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.cmet.2020.05.008
  
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sciencedirect.com/science/article/pii/S1550413120302473
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Coordinate regulation of the senescent state by selective autophagy

1
1. scibot 29 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.devcel.2021.04.008
  
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sciencedirect.com/science/article/pii/S1534580721003178
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Cancer Burden Is Controlled by Mural Cell-β3-Integrin Regulated Crosstalk with Tumor Cells

1
1. scibot 23 Apr 2021
  
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  RRID:AB_331285
  
  DOI: 10.1016/j.cell.2020.02.003
  
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  Curator comments: Phospho-NF-κB p65 (Ser536) (93H1) Rabbit mAb antibody Cell Signaling Technology Cat# 3033
  
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sciencedirect.com/science/article/pii/S0092867420301471
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A hotspot mutation in transcription factor IKZF3 drives B cell neoplasia via transcriptional dysregulation

1
1. scibot 22 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.ccell.2021.02.003
  
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  RRIDCUR:Validated RRID:AB_331284
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sciencedirect.com/science/article/pii/S1535610821001057
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Inhibition of fibroblast IL-6 production by ACKR4 deletion alleviates cardiac remodeling after myocardial infarction

1
1. scibot 16 Apr 2021
  
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  anti-Phospho-NF-κB p65
  
  DOI: 10.1016/j.bbrc.2021.02.013
  
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sciencedirect.com/science/article/pii/S0006291X21001893
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Golgi apparatus-synthesized sulfated glycosaminoglycans mediate polymerization and activation of the cGAMP sensor STING

1
1. scibot 15 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.immuni.2021.03.011
  
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sciencedirect.com/science/article/pii/S1074761321001230
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Optogenetic activation of spinal microglia triggers chronic pain in mice

1
1. scibot 10 Apr 2021
  
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  RRID:AB_331284
  
  DOI: 10.1371/journal.pbio.3001154
  
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  RRID:AB_331284 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC8011727/
Mar 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Decreased miR-214–3p activates NF-κB pathway and aggravates osteoarthritis progression

1
1. scibot 21 Mar 2021
  
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  RRID:AB_331
  
  DOI: 10.1016/j.ebiom.2021.103283
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7957119/
academic.oup.com academic.oup.com

CXCR4 signaling at the fetal-maternal interface may drive inflammation and syncytia formation during ovine pregnancy †

1
1. scibot 02 Mar 2021
  
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  AB_331284
  
  DOI: 10.1093/biolre/ioaa203
  
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academic.oup.com/biolreprod/article/104/2/468/5952668
Feb 2021
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
1. scibot 27 Feb 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.bbi.2020.09.017
  
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sciencedirect.com/science/article/pii/S0889159120315804
www.cell.com www.cell.com

Hematopoietic Progenitor Kinase1 (HPK1) Mediates T Cell Dysfunction and Is a Druggable Target for T Cell-Based Immunotherapies

1
1. scibot 27 Feb 2021
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.ccell.2020.08.001
  
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cell.com/cancer-cell/abstract/S1535-6108(20)30375-5
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Arctigenin protects against depression by inhibiting microglial activation and neuroinflammation via HMGB1/TLR4/NF‐κB and TNF‐α/TNFR1/NF‐κB pathways

1
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  DOI: 10.1111/bph.15261
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15261
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Muscone suppresses inflammatory responses and neuronal damage in a rat model of cervical spondylotic myelopathy by regulating Drp1‐dependent mitochondrial fission

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  DOI: 10.1111/jnc.15011
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15011
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Chicoric acid ameliorate inflammation and oxidative stress in Lipopolysaccharide and d‐galactosamine induced acute liver injury

1
1. scibot 24 Feb 2021
  
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  DOI: 10.1111/jcmm.14935
  
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onlinelibrary.wiley.com/doi/10.1111/jcmm.14935
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Kmt2c mutations enhance HSC self-renewal capacity and convey a selective advantage after chemotherapy

1
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sciencedirect.com/science/article/pii/S2211124721000644
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MDA5 Governs the Innate Immune Response to SARS-CoV-2 in Lung Epithelial Cells

1
1. scibot 22 Jan 2021
  
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  DOI: 10.1016/j.celrep.2020.108628
  
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Cathepsin C promotes breast cancer lung metastasis by modulating neutrophil infiltration and neutrophil extracellular trap formation

1
1. scibot 21 Jan 2021
  
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BPS Publications

1
1. scibot 08 Jan 2021
  
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  DOI: 10.1111/bph.15306
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15306
Dec 2020
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Andrographolide suppresses NLRP3 inflammasome activation in microglia through induction of Parkin-mediated Mitophagy in in-vitro and in-vivo models of Parkinson disease

1
1. scibot 17 Dec 2020
  
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  DOI: 10.1016/j.bbi.2020.09.017
  
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BPS Publications

1
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  RRID:AB_331284
  
  DOI: 10.1111/bph.15237
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7589013/
Oct 2020
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Non-Transcriptional and Translational Function of Canonical NF-κB Signaling in Activating ERK1/2 in IL-1β-Induced COX-2 Expression in Synovial Fibroblasts

1
1. scibot 29 Oct 2020
  
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  DOI: 10.3389/fimmu.2020.579266
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7576893/
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Uric acid drives intestinal barrier dysfunction through TSPO-mediated NLRP3 inflammasome activation

1
1. scibot 27 Oct 2020
  
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  DOI: 10.1007/s00011-020-01409-y
  
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link.springer.com/article/10.1007/s00011-020-01409-y
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IL‐1/IL‐1R signaling induced by all‐trans‐retinal contributes to complement alternative pathway activation in retinal pigment epithelium

1
1. scibot 16 Oct 2020
  
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  RRID:AB_331284
  
  DOI: 10.1002/jcp.30103
  
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onlinelibrary.wiley.com/doi/10.1002/jcp.30103
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TDP-43 Triggers Mitochondrial DNA Release via mPTP to Activate cGAS/STING in ALS

1
1. scibot 10 Oct 2020
  
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  DOI: 10.1016/j.cell.2020.09.020
  
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pubmed.ncbi.nlm.nih.gov/33031745/
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mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression

1
1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.107911
  
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sciencedirect.com/science/article/pii/S2211124720308925
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Arctigenin protects mice from thioglycollate‐induced acute peritonitis

1
1. scibot 25 Sep 2020
  
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pubmed.ncbi.nlm.nih.gov/32960513/
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Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

2
1. scibot 23 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.ccell.2019.12.012
  
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2. scibot 23 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.ccell.2019.12.012
  
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cell.com/cancer-cell/abstract/S1535-6108(19)30582-3
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Chimeric Antigen Receptor Designed to Prevent Ubiquitination and Downregulation Showed Durable Antitumor Efficacy

1
1. scibot 17 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.07.011
  
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sciencedirect.com/science/article/pii/S1074761320303186
elifesciences.org elifesciences.org

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

1
1. scibot 17 Sep 2020
  
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  DOI: 10.7554/eLife.53367
  
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elifesciences.org/articles/53367
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Adipocyte-Derived Versican and Macrophage-Derived Biglycan Control Adipose Tissue Inflammation in Obesity

1
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  DOI: 10.1016/j.celrep.2020.107818
  
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sciencedirect.com/science/article/pii/S2211124720307993
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Type I Interferon Response Dysregulates Host Iron Homeostasis and Enhances Candida glabrata Infection

1
1. scibot 17 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.chom.2020.01.023
  
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sciencedirect.com/science/article/pii/S1931312820300640
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The Natural Compound Notopterol Binds and Targets JAK2/3 to Ameliorate Inflammation and Arthritis

1
1. scibot 16 Sep 2020
  
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  RRID:AB_33128
  
  DOI: 10.1016/j.celrep.2020.108158
  
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sciencedirect.com/science/article/pii/S2211124720311475
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Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages

1
1. scibot 16 Sep 2020
  
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sciencedirect.com/science/article/pii/S1074761320301199
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Genome-wide Screens Implicate Loss of Cullin Ring Ligase 3 in Persistent Proliferation and Genome Instability in TP53-Deficient Cells

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.celrep.2020.03.029
  
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sciencedirect.com/science/article/pii/S2211124720303430
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TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells

1
1. scibot 16 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.03.056
  
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sciencedirect.com/science/article/pii/S2211124720303703
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Glioblastoma Cell Resistance to EGFR and MET Inhibition Can Be Overcome via Blockade of FGFR-SPRY2 Bypass Signaling

1
1. scibot 15 Sep 2020
  
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sciencedirect.com/science/article/pii/S2211124720301686
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SPHK2-Generated S1P in CD11b+ Macrophages Blocks STING to Suppress the Inflammatory Function of Alveolar Macrophages

1
1. scibot 14 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.celrep.2020.02.112
  
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sciencedirect.com/science/article/pii/S221112472030293X
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Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

1
1. scibot 13 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1016/j.immuni.2017.10.016
  
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cell.com/immunity/abstract/S1074-7613(17)30471-5
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BPS Publications

1
1. scibot 13 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1111/bph.15026
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15026
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CD137 Signaling Regulates Acute Colitis via RALDH2-Expressing CD11b−CD103+ DCs

1
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  DOI: 10.1016/j.celrep.2020.02.103
  
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sciencedirect.com/science/article/pii/S2211124720302849
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Molecular Stressors Engender Protein Connectivity Dysfunction through Aberrant N-Glycosylation of a Chaperone

1
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  DOI: 10.1016/j.celrep.2020.107840
  
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sciencedirect.com/science/article/pii/S2211124720308214
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The Autophagy-Initiating Kinase ULK1 Controls RIPK1-Mediated Cell Death

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  DOI: 10.1016/j.celrep.2020.107547
  
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sciencedirect.com/science/article/pii/S2211124720304575
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BPS Publications

1
1. scibot 09 Sep 2020
  
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  RRID:AB_331284
  
  DOI: 10.1111/bph.14972
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14972
academic.oup.com academic.oup.com

DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

1
1. scibot 09 Sep 2020
  
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Deamidation Shunts RelA from Mediating Inflammation to Aerobic Glycolysis

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BPS Publications

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TNFAIP3 Interacting Protein 3 Overexpression Suppresses Nonalcoholic Steatohepatitis by Blocking TAK1 Activation

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Regulatory T Cells Condition Lymphatic Endothelia for Enhanced Transendothelial Migration

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Lysophosphatidic Acid-Mediated GPR35 Signaling in CX3CR1+ Macrophages Regulates Intestinal Homeostasis

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A non‐covalent inhibitor XMU‐MP‐3 overrides ibrutinib‐resistant BtkC481S mutation in B‐cell malignancies

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IKKε and TBK1 in diffuse large B‐cell lymphoma: A possible mechanism of action of an IKKε/TBK1 inhibitor to repress NF‐κB and IL‐10 signalling

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Middle East respiratory syndrome coronavirus nucleocapsid protein suppresses type I and type III interferon induction by targeting RIG-I signaling

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  phospho-NF-κB p65
  
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Norrin mediates tumor-promoting and -suppressive effects in glioblastoma via Notch and WNT

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  anti–phospho-NF-κB p65
  
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Mitochondrial Damage Causes Inflammation via cGAS-STING Signaling in Acute Kidney Injury

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Mechanical regulation of bone homeostasis through p130Cas-mediated alleviation of NF-κB activity

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Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses

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NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor

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TAK1 inhibition in mouse astrocyte cultures ameliorates cytokine‐induced chemokine production and neutrophil migration

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BPS Publications

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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

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CD146 Regulates Growth Factor-Induced mTORC2 Activity Independent of the PI3K and mTORC1 Pathways

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Expression of the double‐stranded RNA‐dependent kinase PKR influences osteosarcoma attachment independent growth, migration, and invasion

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Sustained Secretion of the Antimicrobial Peptide S100A7 Is Dependent on the Downregulation of Caspase-8

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Immune Sensing of Cell Death through Recognition of Histone Sequences by C-Type Lectin-Receptor-2d Causes Inflammation and Tissue Injury

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The Ubiquitin-Editing Enzyme A20 Regulates Synapse Remodeling and Efficacy

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Synthetic Essentiality of Metabolic Regulator PDHK1 in PTEN-Deficient Cells and Cancers

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O-GlcNAc Transferase Suppresses Inflammation and Necroptosis by Targeting Receptor-Interacting Serine/Threonine-Protein Kinase 3

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MST1 Negatively Regulates TNFα-Induced NF-κB Signaling through Modulating LUBAC Activity

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NLRP12 Regulates Anti-viral RIG-I Activation via Interaction with TRIM25

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Systemic network analysis identifies XIAP and IκBα as potential drug targets in TRAIL resistant BRAF mutated melanoma

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Innate Immune Signaling Organelles Display Natural and Programmable Signaling Flexibility

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Three kinds of corneal host cells contribute differently to corneal neovascularization

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Loganetin protects against rhabdomyolysis‐induced acute kidney injury by modulating the toll‐like receptor 4 signalling pathway

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Fatty acid receptor GPR120 promotes breast cancer chemoresistance by upregulating ABC transporters expression and fatty acid synthesis

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IFIT1 Exerts Opposing Regulatory Effects on the Inflammatory and Interferon Gene Programs in LPS-Activated Human Macrophages

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LncRNA CamK-A Regulates Ca2+-Signaling-Mediated Tumor Microenvironment Remodeling

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The Inhibitory Innate Immune Sensor NLRP12 Maintains a Threshold against Obesity by Regulating Gut Microbiota Homeostasis

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Daily Onset of Light and Darkness Differentially Controls Hematopoietic Stem Cell Differentiation and Maintenance

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Non-canonical Activation of the DNA Sensing Adaptor STING by ATM and IFI16 Mediates NF-κB Signaling after Nuclear DNA Damage

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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

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Reversal of angiotensin ll-induced β-cell dedifferentiation via inhibition of NF-κb signaling

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Synthetic Lethal and Convergent Biological Effects of Cancer-Associated Spliceosomal Gene Mutations

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Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A

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Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice

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By Capturing Inflammatory Lipids Released from Dying Cells, the Receptor CD14 Induces Inflammasome-Dependent Phagocyte Hyperactivation

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T Cell Receptor-Regulated TGF-β Type I Receptor Expression Determines T Cell Quiescence and Activation

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B Cell Receptor and CD40 Signaling Are Rewired for Synergistic Induction of the c-Myc Transcription Factor in Germinal Center B Cells

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Extrinsic Phagocyte-Dependent STING Signaling Dictates the Immunogenicity of Dying Cells

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Systematic Functional Annotation of Somatic Mutations in Cancer

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Listeria Adhesion Protein Induces Intestinal Epithelial Barrier Dysfunction for Bacterial Translocation

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Multi-stage Differentiation Defines Melanoma Subtypes with Differential Vulnerability to Drug-Induced Iron-Dependent Oxidative Stress

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CD10+GPR77+ Cancer-Associated Fibroblasts Promote Cancer Formation and Chemoresistance by Sustaining Cancer Stemness

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Salmonella Typhi Colonization Provokes Extensive Transcriptional Changes Aimed at Evading Host Mucosal Immune Defense During Early Infection of Human Intestinal Tissue

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Myeloid Cell-Derived Reactive Oxygen Species Induce Epithelial Mutagenesis

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Ndrg2 deficiency ameliorates neurodegeneration in experimental autoimmune encephalomyelitis

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IL-1β Inhibits Connexin 43 and Disrupts Decidualization of Human Endometrial Stromal Cells Through ERK1/2 and p38 MAP Kinase

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Targeting Interleukin-1β Protects from Aortic Aneurysms Induced by Disrupted Transforming Growth Factor β Signaling

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Divergent JNK Phosphorylation of HDAC3 in Triple-Negative Breast Cancer Cells Determines HDAC Inhibitor Binding and Selectivity

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Adipose Tissue Macrophage-Derived Exosomal miRNAs Can Modulate In Vivo and In Vitro Insulin Sensitivity

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Protein kinase D exerts neuroprotective functions during oxidative stress via Nuclear Factor kappaB‐independent signaling pathways

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An Agonist of the Protective Factor SIRT1 Improves Functional Recovery and Promotes Neuronal Survival by Attenuating Inflammation after Spinal Cord Injury

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Cyclophilin A-regulated ubiquitination is critical for RIG-I-mediated antiviral immune responses

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The Atypical Kinase RIOK1 Promotes Tumor Growth and Invasive Behavior

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CD40 Signaling in Graves Disease Is Mediated Through Canonical and Noncanonical Thyroidal Nuclear Factor κB Activation

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CRISPR/Cas9 Screens Reveal Epstein-Barr Virus-Transformed B Cell Host Dependency Factors

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Context Specificity in Causal Signaling Networks Revealed by Phosphoprotein Profiling

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Astrocytic Process Plasticity and IKKβ/NF-κB in Central Control of Blood Glucose, Blood Pressure, and Body Weight

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The PERK arm of the unfolded protein response regulates satellite cell-mediated skeletal muscle regeneration

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Untitled document

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The Deubiquitinase OTULIN Is an Essential Negative Regulator of Inflammation and Autoimmunity

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The BCL-2 family protein Bid is critical for pro-inflammatory signaling in astrocytes

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