462 Matching Annotations
  1. Jan 2021
  2. www.sciencedirect.com www.sciencedirect.com
    Multi-scale Dynamical Modeling of T Cell Development from an Early Thymic Progenitor State to Lineage Commitment
    1
    1. scibot 22 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108622

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    sciencedirect.com/science/article/pii/S2211124720316119
  3. link.springer.com link.springer.com
    The inflammatory kinase IKKα phosphorylates and stabilizes c-Myc and enhances its activity
    1
    1. scibot 21 Jan 2021
      plasmid_62988

      DOI: 10.1186/s12943-021-01308-8

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    link.springer.com/article/10.1186/s12943-021-01308-8
  4. www.sciencedirect.com www.sciencedirect.com
    Impact of WIN site inhibitor on the WDR5 interactome
    1
    1. scibot 20 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108636

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    sciencedirect.com/science/article/pii/S2211124720316259
  5. www.sciencedirect.com www.sciencedirect.com
    The ER-embedded UBE2J1/RNF26 ubiquitylation complex exerts spatiotemporal control over the endolysosomal pathway
    1
    1. scibot 20 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108659

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    sciencedirect.com/science/article/pii/S221112472031648X
  6. www.sciencedirect.com www.sciencedirect.com
    MAU2 and NIPBL Variants Impair the Heterodimerization of the Cohesin Loader Subunits and Cause Cornelia de Lange Syndrome
    1
    1. scibot 15 Jan 2021
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.107647

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    sciencedirect.com/science/article/pii/S2211124720306008
  7. www.sciencedirect.com www.sciencedirect.com
    A Molecular Mechanism for Turning Off IRE1α Signaling during Endoplasmic Reticulum Stress
    1
    1. scibot 05 Jan 2021
      pSpCas9(BB)-2A-Puro

      DOI: 10.1016/j.celrep.2020.108563

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    sciencedirect.com/science/article/pii/S2211124720315527
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Conformation of the nuclear pore in living cells is modulated by transport state
    1
    1. scibot 05 Jan 2021
      Addgene_62988

      DOI: 10.7554/eLife.60654

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    ncbi.nlm.nih.gov/pmc/articles/PMC7752133/
  9. Dec 2020
  10. www.sciencedirect.com www.sciencedirect.com
    Mechanistic Insights into Regulation of the ALC1 Remodeler by the Nucleosome Acidic Patch
    1
    1. scibot 30 Dec 2020
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.108529

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    sciencedirect.com/science/article/pii/S2211124720315187
  11. www.sciencedirect.com www.sciencedirect.com
    Talpid3-Mediated Centrosome Integrity Restrains Neural Progenitor Delamination to Sustain Neurogenesis by Stabilizing Adherens Junctions
    1
    1. scibot 17 Dec 2020
      PX459

      DOI: 10.1016/j.celrep.2020.108495

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      Curator comments: pSpCas9(BB)-2A-Puro (PX459) V2.0

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    sciencedirect.com/science/article/pii/S2211124720314844
  12. www.sciencedirect.com www.sciencedirect.com
    Defective ALC1 nucleosome remodeling confers PARPi sensitization and synthetic lethality with HRD
    1
    1. scibot 17 Dec 2020
      Addgene_62988

      DOI: 10.1016/j.molcel.2020.12.006

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    sciencedirect.com/science/article/pii/S1097276520308984
  13. www.sciencedirect.com www.sciencedirect.com
    The Rigor and Transparency Index Quality Metric for Assessing Biological and Medical Science Methods
    1
    1. scibot 10 Dec 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.isci.2020.101698

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    sciencedirect.com/science/article/pii/S2589004220308907
  14. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Testes of DAZL null neonatal sheep lack prospermatogonia but maintain normal somatic cell morphology and marker expression
    1
    1. scibot 08 Dec 2020
      RRID:Addgene_62988

      DOI: 10.1002/mrd.23443

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    onlinelibrary.wiley.com/doi/10.1002/mrd.23443
  15. Nov 2020
  16. www.sciencedirect.com www.sciencedirect.com
    Generation of GADD45A gene knockout human embryonic stem cell line using CRISPR/Cas9
    1
    1. scibot 24 Nov 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.scr.2020.102090

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    sciencedirect.com/science/article/pii/S1873506120303913
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-adrenergic receptor signaling evokes the PKA-ASK axis in mature brown adipocytes
    1
    1. scibot 04 Nov 2020
      RRID:Addgene_62988

      DOI: 10.1371/journal.pone.0232645

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    ncbi.nlm.nih.gov/pmc/articles/PMC7591029/
  18. Oct 2020
  19. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Premature aging syndrome showing random chromosome number instabilities with CDC20 mutation
    1
    1. scibot 27 Oct 2020
      RRID:Addgene_62988

      DOI: 10.1111/acel.13251

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    pubmed.ncbi.nlm.nih.gov/33094908/
  20. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Temporal Proteomic Analysis of Herpes Simplex Virus 1 Infection Reveals Cell-Surface Remodeling via pUL56-Mediated GOPC Degradation
    1
    1. scibot 07 Oct 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2020.108235

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    pubmed.ncbi.nlm.nih.gov/33027661/
  21. Sep 2020
  22. www.nature.com www.nature.com
    Generation of myostatin edited horse embryos using CRISPR/Cas9 technology and somatic cell nuclear transfer
    1
    1. scibot 30 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41598-020-72040-4

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    nature.com/articles/s41598-020-72040-4
  23. www.sciencedirect.com www.sciencedirect.com
    CRISPR-Mediated Protein Tagging with Nanoluciferase to Investigate Native Chemokine Receptor Function and Conformational Changes
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.chembiol.2020.01.010

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    sciencedirect.com/science/article/pii/S2451945620300350
  24. www.mdpi.com www.mdpi.com
    Evaluation of the CRISPR/Cas9 Genetic Constructs in Efficient Disruption of Porcine Genes for Xenotransplantation Purposes Along with an Assessment of the Off-Target Mutation Formation
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.3390/genes11060713

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    mdpi.com/2073-4425/11/6/713
  25. link.springer.com link.springer.com
    Increased expression and retention of the secretory chaperone proSAAS following cell stress
    1
    1. scibot 26 Sep 2020
      plasmid_62988

      DOI: 10.1007/s12192-020-01128-7

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    link.springer.com/article/10.1007/s12192-020-01128-7
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    hnRNPDL Phase Separation Is Regulated by Alternative Splicing and Disease-Causing Mutations Accelerate Its Aggregation
    1
    1. scibot 26 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.12.080

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    ncbi.nlm.nih.gov/pmc/articles/PMC6996132/
  27. www.sciencedirect.com www.sciencedirect.com
    Tandem Paired Nicking Promotes Precise Genome Editing with Scarce Interference by p53
    1
    1. scibot 23 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.12.064

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    sciencedirect.com/science/article/pii/S2211124719317218
  28. www.sciencedirect.com www.sciencedirect.com
    The Alazami Syndrome-Associated Protein LARP7 Guides U6 Small Nuclear RNA Modification and Contributes to Splicing Robustness
    1
    1. scibot 23 Sep 2020
      plasmid_62988

      DOI: 10.1016/j.molcel.2020.01.001

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    sciencedirect.com/science/article/pii/S1097276520300010
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Resistance to targeted therapies as a multifactorial, gradual adaptation to inhibitor specific selective pressures
    1
    1. scibot 17 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41467-020-16212-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC7224215/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BMAL1 coordinates energy metabolism and differentiation of pluripotent stem cells
    1
    1. scibot 16 Sep 2020
      plasmid_62988

      DOI: 10.26508/lsa.201900534

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    ncbi.nlm.nih.gov/pmc/articles/PMC7156282/
  31. www.mdpi.com www.mdpi.com
    Rhabdovirus Infection Is Dependent on Serine/Threonine Kinase AP2-Associated Kinase 1
    1
    1. scibot 16 Sep 2020
      RRID:Addgene_62988

      DOI: 10.3390/life10090170

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    mdpi.com/2075-1729/10/9/170
  32. www.sciencedirect.com www.sciencedirect.com
    Atrx Deletion in Neurons Leads to Sexually Dimorphic Dysregulation of miR-137 and Spatial Learning and Memory Deficits
    1
    1. scibot 15 Sep 2020
      Addgene_62988

      DOI: 10.1016/j.celrep.2020.107838

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    sciencedirect.com/science/article/pii/S2211124720308196
  33. link.springer.com link.springer.com
    RBM45 associates with nuclear stress bodies and forms nuclear inclusions during chronic cellular stress and in neurodegenerative diseases
    1
    1. scibot 14 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1186/s40478-020-00965-y

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    link.springer.com/article/10.1186/s40478-020-00965-y
  34. elifesciences.org elifesciences.org
    A human ESC-based screen identifies a role for the translated lncRNA LINC00261 in pancreatic endocrine differentiation
    1
    1. scibot 13 Sep 2020
      RRID:Addgene_62988

      DOI: 10.7554/eLife.58659

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    elifesciences.org/articles/58659
  35. link-springer-com.ezproxy.rice.edu link-springer-com.ezproxy.rice.edu
    FGF primes angioblast formation by inducing ETV2 and LMO2 via FGFR1/BRAF/MEK/ERK
    1
    1. scibot 11 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1007/s00018-020-03630-8

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    link-springer-com.ezproxy.rice.edu/article/10.1007/s00018-020-03630-8
  36. www.sciencedirect.com www.sciencedirect.com
    Loss of TET2 Affects Proliferation and Drug Sensitivity through Altered Dynamics of Cell-State Transitions
    1
    1. scibot 11 Sep 2020
      Addgene_62988

      DOI: 10.1016/j.cels.2020.06.003

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    sciencedirect.com/science/article/pii/S2405471220302003
  37. www.frontiersin.org www.frontiersin.org
    Regulation of the Transferrin Receptor Recycling in Hepatitis C Virus-Replicating Cells
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_62988

      DOI: 10.3389/fcell.2020.00044

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    frontiersin.org/article/10.3389/fcell.2020.00044/full
  38. www.jbc.org www.jbc.org
    Regulation of poly(A)-specific ribonuclease activity by reversible lysine acetylation
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1074/jbc.RA120.012552

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    jbc.org/content/295/30/10255.full
  39. www.nature.com www.nature.com
    The primary cilium and lipophagy translate mechanical forces to direct metabolic adaptation of kidney epithelial cells
    1
    1. scibot 10 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41556-020-0566-0

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    nature.com/articles/s41556-020-0566-0
  40. journals.plos.org journals.plos.org
    All three mammalian MutL complexes are required for repeat expansion in a mouse cell model of the Fragile X-related disorders
    1
    1. scibot 09 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1371/journal.pgen.1008902

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    journals.plos.org/plosgenetics/article
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins
    1
    1. scibot 08 Sep 2020
      plasmid_62988

      DOI: 10.1016/j.cell.2020.06.005

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    ncbi.nlm.nih.gov/pmc/articles/PMC7316060/
  42. www.nature.com www.nature.com
    κB-Ras and Ral GTPases regulate acinar to ductal metaplasia during pancreatic adenocarcinoma development and pancreatitis
    1
    1. scibot 08 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1038/s41467-020-17226-0

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    nature.com/articles/s41467-020-17226-0
  43. www.jbc.org www.jbc.org
    The polycomb group protein PCGF6 mediates germline gene silencing by recruiting histone-modifying proteins to target gene promoters
    1
    1. scibot 07 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1074/jbc.RA119.012121

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    jbc.org/content/295/28/9712.full
  44. www.sciencedirect.com www.sciencedirect.com
    Generation of isogenic Propionyl-CoA Carboxylase Beta Subunit (PCCB) deficient induced pluripotent stem cell lines
    1
    1. scibot 06 Sep 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.scr.2020.101953

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    sciencedirect.com/science/article/pii/S1873506120302543
  45. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness
    1
    1. scibot 06 Sep 2020
      plasmid_62988

      DOI: 10.1002/ijc.32955

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    onlinelibrary.wiley.com/doi/10.1002/ijc.32955
  46. elifesciences.org elifesciences.org
    NuRD subunit CHD4 regulates super-enhancer accessibility in rhabdomyosarcoma and represents a general tumor dependency
    1
    1. scibot 04 Sep 2020
      Addgene_62988

      DOI: 10.7554/eLife.54993

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      RRIDCUR:Validated RRID:Addgene_62988
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    elifesciences.org/articles/54993
  47. www.sciencedirect.com www.sciencedirect.com
    G3BP1 Is a Tunable Switch that Triggers Phase Separation to Assemble Stress Granules
    1
    1. scibot 03 Sep 2020
      Addgene Cat# 62988

      DOI: 10.1016/j.cell.2020.03.046

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    sciencedirect.com/science/article/pii/S0092867420303391
  48. www.sciencedirect.com www.sciencedirect.com
    Partitioning of MLX-Family Transcription Factors to Lipid Droplets Regulates Metabolic Gene Expression
    1
    1. scibot 03 Sep 2020
      Addgene cat# 62988

      DOI: 10.1016/j.molcel.2020.01.014

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    sciencedirect.com/science/article/pii/S1097276520300149
  49. pubs.acs.org pubs.acs.org
    The ATF3 Transcription Factor Is a Short-Lived Substrate of the Arg/N-Degron Pathway
    1
    1. scibot 03 Sep 2020
      RRID: Addgene, 62988

      DOI: 10.1021/acs.biochem.0c00514

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      Curator: @Naa003

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      Curator comments: pSpCas9(BB)-2A-Puro (PX459) V2.0

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    pubs.acs.org/doi/10.1021/acs.biochem.0c00514
  50. Jan 2020
  51. www.sciencedirect.com www.sciencedirect.com
    TAM Kinases Promote Necroptosis by Regulating Oligomerization of MLKL
    1
    1. scibot 13 Jan 2020
      Addgene_62988

      DOI: 10.1016/j.molcel.2019.05.022

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    sciencedirect.com/science/article/pii/S1097276519303946
  52. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Double‐strand breakage in the extrachromosomal double minutes triggers their aggregation in the nucleus, micronucleation, and morphological transformation
    1
    1. scibot 13 Jan 2020
      plasmid_62988

      DOI: 10.1002/gcc.22810

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      RRID:Addgene_62988 RRIDCUR:Validated
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    onlinelibrary.wiley.com/doi/10.1002/gcc.22810
  53. elifesciences.org elifesciences.org
    Implementation of an antibody characterization procedure and application to the major ALS/FTD disease gene C9ORF72
    1
    1. scibot 13 Jan 2020
      plasmid_62988

      DOI: 10.7554/eLife.48363

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      RRID:Addgene_62988 RRIDCUR:Validated
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    elifesciences.org/articles/48363
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of the activity, aggregation, and toxicity of heterodimers of WT and ALS-associated mutant Sod1
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1073/pnas.1902483116

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    ncbi.nlm.nih.gov/pmc/articles/PMC6926019/
  55. www.sciencedirect.com www.sciencedirect.com
    The protective effects of hydrogen sulfide on the myocardial ischemia via regulating Bmal1
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.biopha.2019.109540

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0753332219329245
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Persistent epigenetic memory impedes rescue of the telomeric phenotype in human ICF iPSCs following DNMT3B correction
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.7554/eLife.47859

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    ncbi.nlm.nih.gov/pmc/articles/PMC6897513/
  57. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Hyaluronan synthesis supports glutamate transporter activity
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1111/jnc.14791

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    onlinelibrary.wiley.com/doi/full/10.1111/jnc.14791
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Species specific differences in use of ANP32 proteins by influenza A virus
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.7554/eLife.45066

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    ncbi.nlm.nih.gov/pmc/articles/PMC6548507/
  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tight junction protein occludin regulates progenitor Self-Renewal and survival in developing cortex
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.7554/eLife.49376

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      RRID:Addgene_62988 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6890460/
  60. www.sciencedirect.com www.sciencedirect.com
    MitoRibo-Tag Mice Provide a Tool for In Vivo Studies of Mitoribosome Composition
    1
    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.09.080

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719312847
  61. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      plasmid_62988

      DOI: 10.1016/j.scr.2018.11.010

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      SciCrunch record: plasmid_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1873506118302794
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 13 Jan 2020
      Addgene_62988

      DOI: 10.7554/eLife.41873

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    ncbi.nlm.nih.gov/pmc/articles/PMC6398975/
  63. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.chembiol.2019.02.014

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    sciencedirect.com/science/article/pii/S2451945619300698
  64. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial One-Carbon Pathway Supports Cytosolic Folate Integrity in Cancer Cells
    1
    1. scibot 13 Jan 2020
      Plasmid_62988

      DOI: 10.1016/j.cell.2018.09.041

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      Curator: @Jmenke

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S0092867418312534
  65. www.sciencedirect.com www.sciencedirect.com
    Untitled document
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    1. scibot 13 Jan 2020
      RRID:Addgene_62988

      DOI: 10.1016/j.celrep.2019.02.049

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S2211124719302281
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Untitled document
    1
    1. scibot 12 Jan 2020
      Addgene_62988

      DOI: 10.1016/j.immuni.2018.01.014

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      RRID:Addgene_62988 RRIDCUR:Validated
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    ncbi.nlm.nih.gov/pmc/articles/PMC6251713/
  67. www.sciencedirect.com www.sciencedirect.com
    Activity of the SPCA1 Calcium Pump Couples Sphingomyelin Synthesis to Sorting of Secretory Proteins in the Trans-Golgi Network
    1
    1. scibot 12 Jan 2020
      Plasmid_62988

      DOI: 10.1016/j.devcel.2018.10.012

      Resource: RRID:Addgene_62988

      Curator: @Jmenke

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      RRID:Addgene_62988 RRIDCUR:Validated
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    sciencedirect.com/science/article/pii/S1534580718308335
  68. academic.oup.com academic.oup.com
    Untitled document
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    1. scibot 12 Jan 2020
      plasmid_62988

      DOI: 10.1093/nar/gkz076

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      SciCrunch record: plasmid_62988

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      RRID:Addgene_62988 RRIDCUR:Validated
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkz076/5364135