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Jan 2023
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

MOZ and Menin-MLL Complexes are Complementary Regulators of Chromatin Association and Transcriptional Output in Gastrointestinal Stromal Tumor

1
1. scibot 07 Jan 2023
  
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  DOI: 10.1158/2159-8290.CD-21-0646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9453853/
Dec 2022
link.springer.com link.springer.com

AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer

1
1. scibot 20 Dec 2022
  
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  DOI: 10.1007/s00018-022-04638-y
  
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link.springer.com/article/10.1007/s00018-022-04638-y
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Anti-cancer activity of ST101, a novel antagonist of CCAAT/enhancer binding protein β

1
1. scibot 16 Dec 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1535-7163.MCT-21-0962
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9630826/
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Distinct Tumor Necrosis Factor Alpha Receptors Dictate Stem Cell Fitness Versus Lineage Output in Dnmt3a-Mutant Clonal Hematopoiesis

1
1. scibot 16 Dec 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-22-0086
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9716249/
52.53.155.43 52.53.155.43

can-22-0787-html.html

2
1. scibot 09 Dec 2022
  
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  DOI: 10.1158/0008-5472.can-22-0787
  
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2. scibot 01 Dec 2022
  
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  DOI: 10.1158/0008-5472.can-22-0787
  
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52.53.155.43/fc7b32e58251b729fd8b8d78c9ec2c38de3723af/can-22-0787-html.html
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Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy

1
1. scibot 08 Dec 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1541-7786.MCR-21-0781
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9177734/
Nov 2022
www.sciencedirect.com www.sciencedirect.com

Systematic single-cell pathway analysis to characterize early T cell activation

1
1. scibot 23 Nov 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2022.111697
  
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sciencedirect.com/science/article/pii/S2211124722015716
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Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia

1
1. scibot 04 Nov 2022
  
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  DOI: 10.1016/j.ccell.2022.10.002
  
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sciencedirect.com/science/article/pii/S1535610822004937
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FOXR2 is an epigenetically regulated pan-cancer oncogene that activates ETS transcriptional circuits

1
1. scibot 02 Nov 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/0008-5472.CAN-22-0671
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437574/
Oct 2022
aacrjournals.org aacrjournals.org

CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization

1
1. scibot 27 Oct 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1078-0432.CCR-22-0991
  
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aacrjournals.org/clincancerres/article/28/20/4521/709577/CircIPO7-Promotes-Nasopharyngeal-Carcinoma
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Muscle atrophy phenotype gene expression during spaceflight is linked to a metabolic crosstalk in both the liver and the muscle in mice.

1
1. scibot 26 Oct 2022
  
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  DOI: 10.1016/j.isci.2022.105213
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9576569/
Sep 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Combined – whole blood and skin fibroblasts- transcriptomic analysis in Psoriatic Arthritis reveals molecular signatures of activity, resistance and early response to treatment

1
1. scibot 24 Sep 2022
  
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  SCR_003199
  
  DOI: 10.3389/fimmu.2022.964274
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9493103/
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Characterization of cellular senescence in aging skeletal muscle

1
1. scibot 23 Sep 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1038/s43587-022-00250-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9491365/
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Acquired semi-squamatization during chemotherapy suggests differentiation as a therapeutic strategy for bladder cancer

1
1. scibot 13 Sep 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.ccell.2022.08.010
  
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sciencedirect.com/science/article/pii/S1535610822003749
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Single-cell RNA analysis of chemokine expression in heterogeneous CD14+ monocytes with lipopolysaccharide-induced bone resorption

1
1. scibot 10 Sep 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.yexcr.2022.113343
  
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sciencedirect.com/science/article/pii/S0014482722003366
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NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins

1
1. scibot 10 Sep 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-22-0043
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9437572/
Aug 2022
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Global signalling network analysis of luminal T47D breast cancer cells in response to progesterone

1
1. scibot 27 Aug 2022
  
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  SCR_003199
  
  DOI: 10.3389/fendo.2022.888802
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9403329/
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Dysbiosis in imiquimod-induced psoriasis alters gut immunity and exacerbates colitis development

1
1. scibot 17 Aug 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2022.111191
  
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sciencedirect.com/science/article/pii/S2211124722010087
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Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells

1
1. scibot 04 Aug 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-20-1848
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8831451/
Jul 2022
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells

1
1. scibot 30 Jul 2022
  
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  RRID:SCR_003199
  
  DOI: 10.3390/cells11152298
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9331440/
www.cell.com www.cell.com

EGFR signaling activates intestinal stem cells by promoting mitochondrial biogenesis and β-oxidation

1
1. scibot 27 Jul 2022
  
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  SCR_003199
  
  DOI: 10.1016/j.cub.2022.07.003
  
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cell.com/current-biology/fulltext/S0960-9822(22)01104-6
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Multiomics reveal the central role of pentose phosphate pathway in resident thymic macrophages to cope with efferocytosis-associated stress

1
1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111065
  
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sciencedirect.com/science/article/pii/S2211124722008634
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HMCES modulates the transcriptional regulation of nodal/activin and BMP signaling in mESCs

1
1. scibot 13 Jul 2022
  
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  DOI: 10.1016/j.celrep.2022.111038
  
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sciencedirect.com/science/article/pii/S2211124722008324
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Group 3 innate lymphocytes make a distinct contribution to Type 17 immunity in bladder defence

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1. scibot 09 Jul 2022
  
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  DOI: 10.1016/j.isci.2022.104660
  
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sciencedirect.com/science/article/pii/S2589004222009324
Jun 2022
52.53.155.43 52.53.155.43

cd-21-1022-html.html

3
1. scibot 30 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-21-1022
  
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2. scibot 25 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.cd-21-1022
  
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3. scibot 25 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.cd-21-1022
  
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52.53.155.43/dae3a722cb0f412060233d3b16799226aa47507e/cd-21-1022-html.html
52.53.155.43 52.53.155.43

cd-21-0646-html.html

3
1. scibot 30 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.cd-21-0646
  
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2. scibot 25 Jun 2022
  
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3. scibot 24 Jun 2022
  
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  DOI: 10.1158/2159-8290.cd-21-0646
  
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52.53.155.43/8eb6598be53599407b5cdbf0aa5958efcfba5063/cd-21-0646 (2)-html.html
52.53.155.43 52.53.155.43

mcr-21-0960-html.html

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1. scibot 30 Jun 2022
  
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  DOI: 10.1158/1541-7786.mcr-21-0960
  
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52.53.155.43/9bc55c0a5e9426b13fc2c9301187b4dbb7d33f72/mcr-21-0960-html.html
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MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines

1
1. scibot 22 Jun 2022
  
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  DOI: 10.1016/j.celrep.2022.110988
  
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sciencedirect.com/science/article/pii/S2211124722007744
aacrjournals.org aacrjournals.org

Preclinical modeling of leiomyosarcoma identifies susceptibility to transcriptional CDK inhibitors through antagonism of E2F-driven oncogenic gene expression.

1
1. scibot 14 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1078-0432.CCR-21-3523
  
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aacrjournals.org/clincancerres/article/28/11/2397/698931/Preclinical-Modeling-of-Leiomyosarcoma-Identifies
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Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer

1
1. scibot 14 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1535-7163.MCT-21-0623
  
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aacrjournals.org/mct/article/21/6/936/699192/Porcupine-Inhibition-Disrupts-Mitochondrial
cellandbioscience.biomedcentral.com cellandbioscience.biomedcentral.com

Hepatitis, testicular degeneration, and ataxia in DIDO3-deficient mice with altered mRNA processing

1
1. scibot 09 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1186/s13578-022-00804-8
  
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cellandbioscience.biomedcentral.com/articles/10.1186/s13578-022-00804-8
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Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits.

1
1. scibot 03 Jun 2022
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.jbc.2022.102096
  
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sciencedirect.com/science/article/pii/S0021925822005373
May 2022
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Stromal AR inhibits prostate tumor progression by restraining secretory luminal epithelial cells

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Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment

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Inhibiting USP16 rescues stem cell aging and memory in an Alzheimer’s model

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EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma

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Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module

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Molecular Approaches for the Validation of the Baboon as a Nonhuman Primate Model for the Study of Zika Virus Infection

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Gene body methylation of the lymphocyte-specific gene CARD11 results in its overexpression and regulates cancer mTOR signaling

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Trans-omics analysis of insulin action reveals a cell growth sub-network which co-regulates anabolic processes

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Novel mouse models of bladder cancer identify a prognostic signature associated with risk of disease progression

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Acquired resistance to EZH2 inhibitor GSK343 promotes the differentiation of human DLBCL cell lines towards an ABC-like phenotype

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Cerebrospinal fluid of progressive multiple sclerosis patients reduces differentiation and immune functions of oligodendrocyte progenitor cells

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Identification of pathological grade and prognosis-associated lncRNA for ovarian cancer

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Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression

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EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma

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MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding

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RXRA DT448/9PP generates a dominant active variant capable of inducing maturation in acute myeloid leukemia cells

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Nonsense-mediated RNA decay is a unique vulnerability of cancer cells harboring SF3B1 or U2AF1 mutations

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Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms

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Human CD206+ macrophages associate with diabetes and adipose tissue lymphoid clusters

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Establish an assessment model to characterized metastasis ability Single-cell multiomics reveals heterogeneous cell states linked to metastatic potential in liver cancer cell lines

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EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells

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An AIB1 isoform alters enhancer access and enables progression of early stage triple-negative breast cancer

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Inactivation of mouse transmembrane prolyl 4-hydroxylase increases blood brain barrier permeability and ischemia-induced cerebral neuroinflammation

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Widespread discrepancy in Nnt genotypes and genetic backgrounds complicates granzyme A and other knockout mouse studies

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Multi-Omics Profiling Suggesting Intratumoral Mast Cells as Predictive Index of Breast Cancer Lung Metastasis

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Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy

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MAP3K7 loss drives enhanced androgen signaling and independently confers risk of recurrence in prostate cancer with joint loss of CHD1

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Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors

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Dec 2021
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Stage-stratified molecular profiling of non-muscle-invasive bladder cancer enhances biological, clinical, and therapeutic insight

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Ezh2 is essential for the generation of functional yolk sac derived erythro-myeloid progenitors

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Parity-induced changes to mammary epithelial cells control NKT cell expansion and mammary oncogenesis

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A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells

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Relayed signaling between mesenchymal progenitors and muscle stem cells ensures adaptive stem cell response to increased mechanical load

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Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential

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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

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1. scibot 24 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.110056
  
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sciencedirect.com/science/article/pii/S2211124721015424
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 17 Nov 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1002/1878-0261.13115
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13115
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Homer1a regulates Shank3 expression and underlies behavioral vulnerability to stress in a model of Phelan-McDermid syndrome

1
1. scibot 17 Nov 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.110014
  
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sciencedirect.com/science/article/pii/S2211124721014960
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Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis

1
1. scibot 10 Nov 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.109921
  
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sciencedirect.com/science/article/pii/S2211124721013942
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The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age

1
1. scibot 10 Nov 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.109981
  
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sciencedirect.com/science/article/pii/S2211124721014601
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies

1
1. scibot 05 Nov 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-20-1243
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8406797/
Oct 2021
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Establishment of a prognostic model of ten transcription factors in gastric cancer

1
1. scibot 26 Oct 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.ygeno.2021.10.009
  
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sciencedirect.com/science/article/pii/S0888754321003736
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Role of miR-2392 in driving SARS-CoV-2 infection

1
1. scibot 09 Oct 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.109839
  
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sciencedirect.com/science/article/pii/S2211124721013036
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genomic alterations during the in situ to invasive ductal breast carcinoma transition shaped by the immune system

1
1. scibot 02 Oct 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1541-7786.MCR-20-0949
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8026652/
Sep 2021
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SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

1
1. scibot 28 Sep 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.stem.2021.09.004
  
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sciencedirect.com/science/article/pii/S1934590921003805
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ERα determines the chemoresistant function of mutant p53 involving the switch between lincRNA-p21 and DDB2 expressions

1
1. scibot 24 Sep 2021
  
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  SCR_003199
  
  DOI: 10.1016/j.omtn.2021.07.022
  
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sciencedirect.com/science/article/pii/S2162253121001906
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Follicular dendritic cells restrict interleukin-4 availability in germinal centers and foster memory B cell generation

1
1. scibot 23 Sep 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.immuni.2021.08.028
  
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sciencedirect.com/science/article/pii/S1074761321003629
Aug 2021
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Pro-inflammatory β cell small extracellular vesicles induce β cell failure through activation of the CXCL10/CXCR3 axis in diabetes

1
1. scibot 25 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.109613
  
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sciencedirect.com/science/article/pii/S2211124721010512
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

NF1 regulates mesenchymal glioblastoma plasticity and aggressiveness through the AP-1 transcription factor FOSL1

1
1. scibot 21 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.7554/eLife.64846
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8370767/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Nascent transcript and single-cell RNA-seq analysis defines the mechanism of action of the LSD1 inhibitor INCB059872 in myeloid leukemia

1
1. scibot 21 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.gene.2020.144758
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7401316/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Dietary carbohydrate, particularly glucose, drives B cell lymphopoiesis and function

1
1. scibot 16 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.isci.2021.102835
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8333167/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Heterogeneous disease-propagating stem cells in juvenile myelomonocytic leukemia

1
1. scibot 15 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1084/jem.20180853
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7802370/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Epigenetic regulation of mammalian Hedgehog signaling to the stroma determines the molecular subtype of bladder cancer

1
1. scibot 14 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.7554/eLife.43024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6597241/
www.nature.com www.nature.com

Untitled document

1
1. scibot 13 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1038/s41419-018-1165-x
  
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nature.com/articles/s41419-018-1165-x
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 12 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2019.02.036
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6408623/
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The Polycomb-Dependent Epigenome Controls β Cell Dysfunction, Dedifferentiation, and Diabetes

1
1. scibot 12 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.cmet.2018.04.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5989056/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2018.12.094
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6344342/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Untitled document

1
1. scibot 10 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1002/jcb.27567
  
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onlinelibrary.wiley.com/doi/full/10.1002/jcb.27567
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Studying immunotherapy resistance in a melanoma autologous humanized mouse xenograft.

1
1. scibot 07 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1158/1541-7786.MCR-20-0686
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7864867/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 05 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1038/s41419-018-1165-x
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6235921/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 04 Aug 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2019.03.104
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6486482/
Jul 2021
www.nature.com www.nature.com

A kinase-independent role for CDK8 in BCR-ABL1 + leukemia

1
1. scibot 31 Jul 2021
  
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  GSEA
  
  DOI: 10.1038/s41467-019-12656-x
  
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  Curator: @Naa003
  
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nature.com/articles/s41467-019-12656-x
www.sciencedirect.com www.sciencedirect.com

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.immuni.2018.10.012
  
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sciencedirect.com/science/article/pii/S1074761318304771
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Untitled document

1
1. scibot 31 Jul 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.immuni.2018.01.015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5828517/
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Unravelling Intratumoral Heterogeneity through High-Sensitivity Single-Cell Mutational Analysis and Parallel RNA Sequencing

1
1. scibot 31 Jul 2021
  
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  RRID:SCR_003199
  
  DOI: 10.1016/j.molcel.2019.01.009
  
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  Curator: @evieth
  
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  RRID:SCR_003199 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276519300097
www.jci.org www.jci.org

Drp1S600 phosphorylation regulates mitochondrial fission and progression of nephropathy in diabetic mice

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1172/JCI127277
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
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jci.org/articles/view/127277
www.nature.com www.nature.com

Modelling human hepato-biliary-pancreatic organogenesis from the foregut–midgut boundary

1
1. scibot 30 Jul 2021
  
  in Public
  
  Gene set enrichment analysis
  
  DOI: 10.1038/s41586-019-1598-0
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
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nature.com/articles/s41586-019-1598-0
www.mdpi.com www.mdpi.com

FOXO1 Confers Maintenance of the Dark Zone Proliferation and Survival Program and Can Be Pharmacologically Targeted in Burkitt Lymphoma

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.3390/cancers11101427
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
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mdpi.com/2072-6694/11/10/1427/htm
www.nature.com www.nature.com

Urothelial organoids originating from Cd49f high mouse stem cells display Notch-dependent differentiation capacity

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1038/s41467-019-12307-1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
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  RRID:SCR_003199 RRIDCUR:Missing
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nature.com/articles/s41467-019-12307-1
rupress.org rupress.org

Chemotherapy-induced senescent cancer cells engulf other cells to enhance their survival

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1083/jcb.201904051
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
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  RRID:SCR_003199 RRIDCUR:Missing
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rupress.org/jcb/article/218/11/3827/120917/Chemotherapy-induced-senescent-cancer-cells-engulf
www.nature.com www.nature.com

Maternal vitamin C regulates reprogramming of DNA methylation and germline development

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1038/s41586-019-1536-1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
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  RRID:SCR_003199 RRIDCUR:Missing
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nature.com/articles/s41586-019-1536-1
elifesciences.org elifesciences.org

FAK activity sustains intrinsic and acquired ovarian cancer resistance to platinum chemotherapy

1
1. scibot 30 Jul 2021
  
  in Public
  
  Gene Set Enrichment Analysis
  
  DOI: 10.7554/eLife.47327
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
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  RRID:SCR_003199 RRIDCUR:Missing
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elifesciences.org/articles/47327
elifesciences.org elifesciences.org

Mutationally-activated PI3’-kinase-α promotes de-differentiation of lung tumors initiated by the BRAFV600E oncoprotein kinase

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.7554/eLife.43668
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

elifesciences.org/articles/43668
www.embopress.org www.embopress.org

CDK12 drives breast tumor initiation and trastuzumab resistance via WNT and IRS1‐ErbB‐PI3K signaling

1
1. scibot 30 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.15252/embr.201948058
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

embopress.org/doi/10.15252/embr.201948058
f1000research.com f1000research.com

The unfolded protein response and its potential role in Huntington ́s disease elucidated by a systems biology approach

6
1. scibot 30 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
2. scibot 30 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
3. scibot 30 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
4. scibot 30 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
5. scibot 30 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
6. scibot 27 Jul 2021
  
  in Public
  
  nif-0000-30629
  
  DOI: 10.12688/f1000research.6358.1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @jcabotaj
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Validated
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RRID:SCR_003199

RRIDCUR:Validated

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scibot

URL

f1000research.com/articles/4-103/v1
www.sciencedirect.com www.sciencedirect.com

Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1016/j.cell.2018.09.051
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Validated RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S0092867418312637
www.sciencedirect.com www.sciencedirect.com

Proteomics, Post-translational Modifications, and Integrative Analyses Reveal Molecular Heterogeneity within Medulloblastoma Subgroups

1
1. scibot 30 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1016/j.ccell.2018.08.004
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Validated RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Validated

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818303581
elifesciences.org elifesciences.org

Toxoplasma gondii infection drives conversion of NK cells into ILC1-like cells

1
1. scibot 29 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.7554/eLife.47605
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

elifesciences.org/articles/47605
www.nature.com www.nature.com

MYC competes with MiT/TFE in regulating lysosomal biogenesis and autophagy through an epigenetic rheostat

1
1. scibot 29 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1038/s41467-019-11568-0
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

nature.com/articles/s41467-019-11568-0
www.nature.com www.nature.com

Intracellular Zn 2+ transients modulate global gene expression in dissociated rat hippocampal neurons

1
1. scibot 29 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1038/s41598-019-45844-2
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

nature.com/articles/s41598-019-45844-2
www.sciencedirect.com www.sciencedirect.com

Integrin-α3 Is a Functional Marker of Ex Vivo Expanded Human Long-Term Hematopoietic Stem Cells

1
1. scibot 29 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.celrep.2019.06.084
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S2211124719308642
www.sciencedirect.com www.sciencedirect.com

WNT-Mediated Regulation of FOXO1 Constitutes a Critical Axis Maintaining Pubertal Mammary Stem Cell Homeostasis

1
1. scibot 29 Jul 2021
  
  in Public
  
  Gene set enrichment analysis
  
  DOI: 10.1016/j.devcel.2017.10.007
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1534580717308201
www.sciencedirect.com www.sciencedirect.com

Epigenetic Compensation Promotes Liver Regeneration

1
1. scibot 29 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.devcel.2019.05.034
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1534580719304472
www.sciencedirect.com www.sciencedirect.com

Mutations in an Innate Immunity Pathway Are Associated with Poor Overall Survival Outcomes and Hypoxic Signaling in Cancer

1
1. scibot 28 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2018.11.093
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @evieth
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Unrecognized RRID:SCR_003199
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RRIDCUR:Unrecognized

RRID:SCR_003199

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scibot

URL

sciencedirect.com/science/article/pii/S2211124718318849
www.sciencedirect.com www.sciencedirect.com

Complement C3aR Inactivation Attenuates Tau Pathology and Reverses an Immune Network Deregulated in Tauopathy Models and Alzheimer’s Disease

1
1. scibot 28 Jul 2021
  
  in Public
  
  SCR_003199
  
  DOI: 10.1016/j.neuron.2018.10.031
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

sciencedirect.com/science/article/pii/S0896627318309395
www.nature.com www.nature.com

Vps11 and Vps18 of Vps-C membrane traffic complexes are E3 ubiquitin ligases and fine-tune signalling

1
1. scibot 28 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1038/s41467-019-09800-y
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

nature.com/articles/s41467-019-09800-y
www.sciencedirect.com www.sciencedirect.com

p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

1
1. scibot 28 Jul 2021
  
  in Public
  
  Gene Set Enrichment Analysis (GSEA)
  
  DOI: 10.1016/j.ccell.2019.01.006
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

Annotators

scibot

URL

sciencedirect.com/science/article/pii/S1535610819300406
onlinelibrary.wiley.com onlinelibrary.wiley.com

Cooperation of PU.1 With IRF8 and NFATc1 Defines Chromatin Landscapes During RANKL‐Induced Osteoclastogenesis

1
1. scibot 28 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1002/jbmr.3689
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

onlinelibrary.wiley.com/doi/full/10.1002/jbmr.3689
link.springer.com link.springer.com

Tributyltin induces a transcriptional response without a brite adipocyte signature in adipocyte models

1
1. scibot 28 Jul 2021
  
  in Public
  
  Gene Set Enrichment Analysis
  
  DOI: 10.1007/s00204-018-2268-y
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
Visit annotations in context

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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

link.springer.com/article/10.1007/s00204-018-2268-y
www.sciencedirect.com www.sciencedirect.com

Resistance to Epigenetic-Targeted Therapy Engenders Tumor Cell Vulnerabilities Associated with Enhancer Remodeling

1
1. scibot 28 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.ccell.2018.11.005
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRIDCUR:Missing RRID:SCR_003199
Visit annotations in context

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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818305269
www.sciencedirect.com www.sciencedirect.com

Janus Kinase 1 Plays a Critical Role in Mammary Cancer Progression

1
1. scibot 27 Jul 2021
  
  in Public
  
  Gene Set Enrichment Analysis
  
  DOI: 10.1016/j.celrep.2018.10.063
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
Visit annotations in context

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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S221112471831667X
www.sciencedirect.com www.sciencedirect.com

OTUB2 Promotes Cancer Metastasis via Hippo-Independent Activation of YAP and TAZ

1
1. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.molcel.2018.10.030
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1097276518308906
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Inhibition of Amino Acid Metabolism Selectively Targets Human Leukemia Stem Cells

1
1. scibot 27 Jul 2021
  
  in Public
  
  Gene Expression Enrichment Analysis
  
  DOI: 10.1016/j.ccell.2018.10.005
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
Visit annotations in context

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RRID:SCR_003199

RRIDCUR:Missing

Annotators

scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC6280965/
onlinelibrary.wiley.com onlinelibrary.wiley.com

Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain

1
1. scibot 27 Jul 2021
  
  in Public
  
  gene set enrichment analysis
  
  DOI: 10.1111/jnc.14469
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

onlinelibrary.wiley.com/doi/full/10.1111/jnc.14469
www.sciencedirect.com www.sciencedirect.com

Genetic Analysis Reveals AMPK Is Required to Support Tumor Growth in Murine Kras-Dependent Lung Cancer Models

1
1. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.cmet.2018.10.005
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1550413118306375
www.sciencedirect.com www.sciencedirect.com

Inhibiting Inflammation with Myeloid Cell-Specific Nanobiologics Promotes Organ Transplant Acceptance

1
1. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.immuni.2018.09.008
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1074761318304230
www.sciencedirect.com www.sciencedirect.com

BRD4 Inhibition Is Synthetic Lethal with PARP Inhibitors through the Induction of Homologous Recombination Deficiency

1
1. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.ccell.2018.01.019
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818300199
www.sciencedirect.com www.sciencedirect.com

Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

1
1. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.stem.2018.05.027
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @Jmenke
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S1934590918302820
www.sciencedirect.com www.sciencedirect.com

Multi-organ Mapping of Cancer Risk

2
1. scibot 27 Jul 2021
  
  in Public
  
  gene set enrichment analyses (GSEA
  
  DOI: 10.1016/j.cell.2016.07.045
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
2. scibot 27 Jul 2021
  
  in Public
  
  GSEA
  
  DOI: 10.1016/j.cell.2016.07.045
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @gabimpine
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199 RRIDCUR:Missing
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RRID:SCR_003199

RRIDCUR:Missing

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scibot

URL

sciencedirect.com/science/article/pii/S0092867416309953
www.sciencedirect.com www.sciencedirect.com

Ezh2 and Runx1 Mutations Collaborate to Initiate Lympho-Myeloid Leukemia in Early Thymic Progenitors

1
1. scibot 27 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1016/j.ccell.2018.01.006
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

sciencedirect.com/science/article/pii/S1535610818300060
www.sciencedirect.com www.sciencedirect.com

Deletion of RBMX RGG/RG motif in Shashi-XLID syndrome leads to aberrant p53 activation and neuronal differentiation defects

1
1. scibot 14 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1016/j.celrep.2021.109337
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

sciencedirect.com/science/article/pii/S2211124721007130
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Resistance to different anthracycline chemotherapeutics elicits distinct and actionable primary metabolic dependencies in breast cancer

1
1. scibot 03 Jul 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.7554/eLife.65150
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

ncbi.nlm.nih.gov/pmc/articles/PMC8238502/
Jun 2021
cancerdiscovery.aacrjournals.org cancerdiscovery.aacrjournals.org

LKB1/STK11 is a tumor suppressor in the progression of myeloproliferative neoplasms

1
1. scibot 29 Jun 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1158/2159-8290.CD-20-1353
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

cancerdiscovery.aacrjournals.org/content/11/6/1398
peerj.com peerj.com

Involvement of plasminogen activator inhibitor-1 and its related molecules in atrial fibrosis in patients with atrial fibrillation

1
1. scibot 09 Jun 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.7717/peerj.11488
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
  SciCrunch record: RRID:SCR_003199
  
  What is this?
  
  RRID:SCR_003199
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RRID:SCR_003199

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scibot

URL

peerj.com/articles/11488
www.nature.com www.nature.com

MicroRNA-200c restoration reveals a cytokine profile to enhance M1 macrophage polarization in breast cancer

1
1. scibot 02 Jun 2021
  
  in Public
  
  RRID:SCR_003199
  
  DOI: 10.1038/s41523-021-00273-1
  
  Resource: Gene Set Enrichment Analysis (RRID:SCR_003199)
  
  Curator: @scibot
  
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JunB is a key regulator of multiple myeloma bone marrow angiogenesis

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Implementation of dietary methionine restriction using casein after selective, oxidative deletion of methionine

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Loss of Ambra1 promotes melanoma growth and invasion

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LDLR inhibition promotes hepatocellular carcinoma proliferation and metastasis by elevating intracellular cholesterol synthesis through MEK/ERK signaling pathway

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Dynamic profiles and transcriptional preferences of histone modifications during spermiogenesis

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MYC up-regulation confers resistance to everolimus and establishes vulnerability to cyclin dependent kinase inhibitors in pancreatic neuroendocrine neoplasms cells

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Clinical responsiveness to All-trans Retinoic Acid is potentiated by LSD1 inhibition and associated with a quiescent transcriptome in myeloid malignancies

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HAND1 and BARX1 act as transcriptional and anatomic determinants of malignancy in gastrointestinal stromal tumor

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Gut microbiota condition the therapeutic efficacy of trastuzumab in HER2-positive breast cancer

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Sequential CRISPR gene editing in human iPSCs charts the clonal evolution of myeloid leukemia and identifies early disease targets

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Non-canonical Targets of HIF1a Impair Oligodendrocyte Progenitor Cell Function

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A Dedicated Evolutionarily Conserved Molecular Network Licenses Differentiated Cells to Return to the Cell Cycle

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Developmentally Programmed Tankyrase Activity Upregulates β-Catenin and Licenses Progression of Embryonic Genome Activation

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Pathological angiogenesis in retinopathy engages cellular senescence and is amenable to therapeutic elimination via BCL-xL inhibition

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ARHGAP20 Expression Inhibited HCC Progression by Regulating the PI3K-AKT Signaling Pathway

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Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome

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A High-Resolution Map of Human Enhancer RNA Loci Characterizes Super-enhancer Activities in Cancer

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Immunogenomic Landscape of Hematological Malignancies

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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

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Decline in IGF1 in the bone marrow microenvironment initiates hematopoietic stem cell aging

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Time-resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling

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Mar 2021
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H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model

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Global analysis of shared T cell specificities in human non-small cell lung cancer enables HLA inference and antigen discovery

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Transcriptional programming drives Ibrutinib-resistance evolution in mantle cell lymphoma

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Proteomic and bioinformatic profiling of neutrophils in CLL reveals functional defects that predispose to bacterial infections

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A Ketogenic Diet Differentially Affects Neuron And Astrocyte Transcription

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Zinc Finger Protein CTCF Regulates Extracellular Matrix (ECM)-Related Gene Expression Associated With the Wnt Signaling Pathway in Gastric Cancer

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Transcriptional networks identify synaptotagmin-like 3 as a regulator of cortical neuronal migration during early neurodevelopment

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Single-cell landscape of the ecosystem in early-relapse hepatocellular carcinoma

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Heterogenous Populations of Tissue-Resident CD8+ T Cells Are Generated in Response to Infection and Malignancy

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The kinase PDK1 is critical for promoting T follicular helper cell differentiation

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  DOI: 10.7554/eLife.61406
  
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Unique signatures of stress-induced senescent human astrocytes

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Distinct Transcriptional Responses across Tissue-Resident Macrophages to Short-Term and Long-Term Metabolic Challenge

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Jan 2021
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Failures of nerve regeneration caused by aging or chronic denervation are rescued by restoring Schwann cell c-Jun

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  DOI: 10.7554/eLife.62232
  
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Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells

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  DOI: 10.7554/eLife.59142
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7803373/
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Selective activation of FZD7 promotes mesendodermal differentiation of human pluripotent stem cells

1
1. scibot 06 Jan 2021
  
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  DOI: 10.7554/eLife.63060
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7759383/
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Circadian VIPergic Neurons of the Suprachiasmatic Nuclei Sculpt the Sleep-Wake Cycle

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1. scibot 19 Dec 2020
  
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  DOI: 10.1016/j.neuron.2020.08.001
  
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cell.com/neuron/fulltext/S0896-6273(20)30608-5
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RSPO3 is a marker candidate for predicting tumor aggressiveness in ovarian cancer

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1. scibot 13 Dec 2020
  
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  DOI: 10.21037/atm-20-3731
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7723610/
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Identification of tumor‐associated macrophage subsets that are associated with breast cancer prognosis

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1. scibot 11 Dec 2020
  
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  DOI: 10.1002/ctm2.239
  
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onlinelibrary.wiley.com/doi/full/10.1002/ctm2.239
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Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact

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1. scibot 07 Dec 2020
  
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  DOI: 10.1016/j.cell.2020.11.002
  
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sciencedirect.com/science/article/pii/S0092867420314616
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High neural activity accelerates the decline of cognitive plasticity with age in Caenorhabditis elegans

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1. scibot 07 Dec 2020
  
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  DOI: 10.7554/eLife.59711
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7685709/
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16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

1
1. scibot 07 Dec 2020
  
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  DOI: 10.7554/eLife.58178
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7695459/
Nov 2020
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Tumor Infiltrating Effector Memory Antigen-Specific CD8+ T Cells Predict Response to Immune Checkpoint Therapy

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1. scibot 25 Nov 2020
  
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  DOI: DOI:10.3389/fimmu.2020.584423
  
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frontiersin.org/articles/10.3389/fimmu.2020.584423/full
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Mapping endothelial-cell diversity in cerebral cavernous malformations at single-cell resolution

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1. scibot 12 Nov 2020
  
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  DOI: 10.7554/eLife.61413
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7609066/
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Chemical and molecular bases of dome formation in human colorectal cancer cells mediated by sulphur compounds from Cucumis melo var. conomon

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1. scibot 10 Nov 2020
  
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  DOI: 10.1002/2211-5463.13001
  
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febs.onlinelibrary.wiley.com/doi/10.1002/2211-5463.13001
Oct 2020
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Primary Human Colonic Mucosal Barrier Crosstalk with Super Oxygen-Sensitive Faecalibacterium prausnitzii in Continuous Culture

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sciencedirect.com/science/article/pii/S2666634020300143
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Purification of pancreatic endocrine subsets reveals increased iron metabolism in beta-cells

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1. scibot 17 Oct 2020
  
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  DOI: 10.1016/j.molmet.2020.101060
  
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sciencedirect.com/science/article/pii/S2212877820301344
Sep 2020
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Genomic Repeats Categorize Genes with Distinct Functions for Orchestrated Regulation

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.celrep.2020.02.048
  
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Snai2 Maintains Bone Marrow Niche Cells by Repressing Osteopontin Expression

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1. scibot 26 Sep 2020
  
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  DOI: 10.1016/j.devcel.2020.04.012
  
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C/EBPα and GATA-2 Mutations Induce Bilineage Acute Erythroid Leukemia through Transformation of a Neomorphic Neutrophil-Erythroid Progenitor

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.ccell.2020.03.022
  
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Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression

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1. scibot 23 Sep 2020
  
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  DOI: 10.1016/j.immuni.2020.01.003
  
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sciencedirect.com/science/article/pii/S1074761320300303

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