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569 Matching Annotations

Feb 2022
elifesciences.org elifesciences.org

FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons

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1. scibot 16 Feb 2022
  
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  DOI: 10.7554/eLife.71892
  
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elifesciences.org/articles/71892
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Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model

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1. scibot 16 Feb 2022
  
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  DOI: 10.1016/j.biopsych.2020.05.024
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7704921/
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Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast

1
1. scibot 02 Feb 2022
  
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  DOI: 10.1158/1541-7786.MCR-21-0025
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8349796/
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Multi-Omics Profiling Suggesting Intratumoral Mast Cells as Predictive Index of Breast Cancer Lung Metastasis

1
1. scibot 02 Feb 2022
  
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  DOI: 10.3389/fonc.2021.788778
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8801492/
Jan 2022
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Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy

1
1. scibot 22 Jan 2022
  
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  DOI: 10.1038/s41467-021-27869-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8758788/
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Quiescent human glioblastoma cancer stem cells drive tumor initiation, expansion, and recurrence following chemotherapy

1
1. scibot 11 Jan 2022
  
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  DOI: 10.1016/j.devcel.2021.12.007
  
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sciencedirect.com/science/article/pii/S1534580721009965
Dec 2021
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Regulatory T-cells inhibit microglia-induced pain hypersensitivity in female mice

1
1. scibot 11 Dec 2021
  
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  DOI: 10.7554/eLife.69056
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8639143/
Nov 2021
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Interdependence of neural network dysfunction and microglial alterations in Alzheimer’s disease-related models

1
1. scibot 16 Nov 2021
  
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  DOI: 10.1016/j.isci.2021.103245
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8561005/
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Epithelial-myeloid exchange of MHC class II constrains immunity and microbiota composition

1
1. scibot 03 Nov 2021
  
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  DOI: 10.1016/j.celrep.2021.109916
  
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sciencedirect.com/science/article/pii/S2211124721013899
Oct 2021
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Establishment of a prognostic model of ten transcription factors in gastric cancer

1
1. scibot 26 Oct 2021
  
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  DOI: 10.1016/j.ygeno.2021.10.009
  
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sciencedirect.com/science/article/pii/S0888754321003736
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Single-cell RNA sequencing for the identification of early-stage lung cancer biomarkers from circulating blood

1
1. scibot 23 Oct 2021
  
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  DOI: 10.1038/s41525-021-00248-y
  
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nature.com/articles/s41525-021-00248-y
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Role of miR-2392 in driving SARS-CoV-2 infection

1
1. scibot 09 Oct 2021
  
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  DOI: 10.1016/j.celrep.2021.109839
  
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sciencedirect.com/science/article/pii/S2211124721013036
Sep 2021
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Tissue environment, not ontogeny, defines murine intestinal intraepithelial T lymphocytes

1
1. scibot 30 Sep 2021
  
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  DOI: 10.7554/eLife.70055
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8463072/
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SATB2 preserves colon stem cell identity and mediates ileum-colon conversion via enhancer remodeling

1
1. scibot 28 Sep 2021
  
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  DOI: 10.1016/j.stem.2021.09.004
  
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sciencedirect.com/science/article/pii/S1934590921003805
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Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave

1
1. scibot 14 Sep 2021
  
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  DOI: 10.7554/eLife.66738
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8425950/
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An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens

1
1. scibot 11 Sep 2021
  
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  DOI: 10.7554/eLife.69142
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8423448/
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Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia

1
1. scibot 08 Sep 2021
  
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  DOI: 10.1016/j.immuni.2021.08.007
  
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sciencedirect.com/science/article/pii/S107476132100337X
Aug 2021
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Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity

1
1. scibot 15 Aug 2021
  
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  RRID:SCR_010943
  
  DOI: 10.1016/j.celrep.2021.109494
  
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sciencedirect.com/science/article/pii/S2211124721009219
journals.sagepub.com journals.sagepub.com

SAGE Journals: Your gateway to world-class research journals

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1. scibot 13 Aug 2021
  
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  RRID:SCR_010943
  
  DOI: 10.1177/1759091419843393
  
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journals.sagepub.com/doi/full/10.1177/1759091419843393
elifesciences.org elifesciences.org

Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway

1
1. scibot 12 Aug 2021
  
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  DOI: 10.7554/eLife.25157
  
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elifesciences.org/articles/25157
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The COVIDome Explorer researcher portal

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1. scibot 05 Aug 2021
  
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  DOI: 10.1016/j.celrep.2021.109527
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8316015/
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A 5‐gene prognostic nomogram predicting survival probability of glioblastoma patients

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1. scibot 03 Aug 2021
  
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  DOI: 10.1002/brb3.1258
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6456771/
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Untitled document

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1. scibot 01 Aug 2021
  
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  DOI: 10.7554/eLife.30054
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5736353/
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Untitled document

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1. scibot 01 Aug 2021
  
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  RRID:SCR_010943
  
  DOI: 10.1016/j.celrep.2019.03.093
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6499398/
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Untitled document

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1. scibot 01 Aug 2021
  
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  DOI: 10.1016/j.immuni.2018.01.015
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5828517/
Jul 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

DNA hypermethylation is associated with invasive phenotype of malignant melanoma

1
1. scibot 31 Jul 2021
  
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  limma
  
  DOI: 10.1111/exd.14047
  
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onlinelibrary.wiley.com/doi/full/10.1111/exd.14047
www.nature.com www.nature.com

Mitofusins regulate lipid metabolism to mediate the development of lung fibrosis

1
1. scibot 31 Jul 2021
  
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  Limma
  
  DOI: 10.1038/s41467-019-11327-1
  
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nature.com/articles/s41467-019-11327-1
journals.sagepub.com journals.sagepub.com

Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.1177/1759091419843393
  
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journals.sagepub.com/doi/abs/10.1177/1759091419843393
elifesciences.org elifesciences.org

Untitled document

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1. scibot 31 Jul 2021
  
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  DOI: 10.7554/eLife.20542
  
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elifesciences.org/articles/20542
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Untitled document

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1. scibot 31 Jul 2021
  
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  RRID:SCR_010943
  
  DOI: 10.1002/brb3.1258
  
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onlinelibrary.wiley.com/doi/full/10.1002/brb3.1258
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

1
1. scibot 31 Jul 2021
  
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  DOI: 10.7554/eLife.39982
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6342529/
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The pharmalogical reactivation of p53 function improves breast tumor cell lysis by granzyme B and NK cells through induction of autophagy

1
1. scibot 30 Jul 2021
  
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  DOI: 10.1038/s41419-019-1950-1
  
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nature.com/articles/s41419-019-1950-1
onlinelibrary.wiley.com onlinelibrary.wiley.com

SNAIL1 employs β‐Catenin‐LEF1 complexes to control colorectal cancer cell invasion and proliferation

1
1. scibot 30 Jul 2021
  
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  DOI: 10.1002/ijc.32644
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32644
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Mega-analysis of gene expression in mouse models of Alzheimer’s disease

1
1. scibot 29 Jul 2021
  
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  DOI: 10.1523/ENEURO.0226-19.2019
  
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eneuro.org/content/6/6/ENEURO.0226-19.2019
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Liver Is a Generative Site for the B Cell Response to Ehrlichia muris

1
1. scibot 29 Jul 2021
  
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  RRID: SCR_010943
  
  DOI: 10.1016/j.immuni.2019.10.004
  
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sciencedirect.com/science/article/pii/S1074761319304480
elifesciences.org elifesciences.org

PUMILIO, but not RBMX, binding is required for regulation of genomic stability by noncoding RNA NORAD

1
1. scibot 29 Jul 2021
  
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  Limma
  
  DOI: 10.7554/eLife.48625
  
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elifesciences.org/articles/48625
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Integrating Gene and Protein Expression Reveals Perturbed Functional Networks in Alzheimer’s Disease

1
1. scibot 29 Jul 2021
  
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  limma
  
  DOI: 10.1016/j.celrep.2019.06.073
  
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Inducible and reversible phenotypes in a novel mouse model of Friedreich's Ataxia.

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Drug Screening in Human PSC-Cardiac Organoids Identifies Pro-proliferative Compounds Acting via the Mevalonate Pathway

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A chemical toolbox for the study of bromodomains and epigenetic signaling

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p53 Is a Master Regulator of Proteostasis in SMARCB1-Deficient Malignant Rhabdoid Tumors

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The RNA-Binding Protein PUM2 Impairs Mitochondrial Dynamics and Mitophagy During Aging

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A Metabolic Checkpoint for the Yeast-to-Hyphae Developmental Switch Regulated by Endogenous Nitric Oxide Signaling

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The Anti-amyloid Compound DO1 Decreases Plaque Pathology and Neuroinflammation-Related Expression Changes in 5xFAD Transgenic Mice

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Neuronal calcineurin transcriptional targets parallel changes observed in Alzheimer disease brain

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Identity Noise and Adipogenic Traits Characterize Dermal Fibroblast Aging

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An Interleukin-23-Interleukin-22 Axis Regulates Intestinal Microbial Homeostasis to Protect from Diet-Induced Atherosclerosis

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Genetic and pharmacological evidence for kinetic competition between alternative poly(A) sites in yeast

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Monocytic Ontogeny of Regenerated Macrophages Characterizes the Mesotheliomagenic Responses to Carbon Nanotubes

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Follicular lymphoma triggers phenotypic and functional remodeling of the human lymphoid stromal cell landscape

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Nascent RNA antagonizes the interaction of a set of regulatory proteins with chromatin

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Tumor vessel co-option probed by single-cell analysis

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Patient Derived Colonoids as Drug Testing Platforms–Critical Importance of Oxygen Concentration

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Conserved pan-cancer microenvironment subtypes predict response to immunotherapy

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Stem-like cells drive NF1-associated MPNST functional heterogeneity and tumor progression

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Morphological and genomic shifts in mole-rat ‘queens’ increase fecundity but reduce skeletal integrity

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As above, so below: Whole transcriptome profiling demonstrates strong molecular similarities between avian dorsal and ventral pallial subdivisions

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Mesenchymal Niche-Derived Neuregulin-1 Drives Intestinal Stem Cell Proliferation and Regeneration of Damaged Epithelium

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FEBS Press

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Recording of DNA-binding events reveals the importance of a repurposed Candida albicans regulatory network for gut commensalism

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Erosion of human X chromosome inactivation causes major remodeling of the iPSC proteome

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LncRNA CALB2 sponges miR-30b-3p to promote odontoblast differentiation of human dental pulp stem cells via up-regulating RUNX2

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Cell Lineage-Based Stratification for Glioblastoma

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Immunogenomic Landscape of Hematological Malignancies

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Early stem cell aging in the mature brain

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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

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Molecular pathways behind acquired obesity: adipose tissue and skeletal muscle multiomics in monozygotic twin pairs discordant for BMI

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Seroconversion stages COVID19 into distinct pathophysiological states

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Repurposing of the Antiepileptic Drug Levetiracetam to Restrain Neuroendocrine Prostate Cancer and Inhibit Mast Cell Support to Adenocarcinoma

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Antagonism of PP2A is an independent and conserved function of HIV-1 Vif and causes cell cycle arrest

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Construction of a MicroRNA-Based Nomogram for Prediction of Lung Metastasis in Breast Cancer Patients

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Plasticity of Epididymal Adipose Tissue in Response to Diet-Induced Obesity at Single-Nucleus Resolution

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Sulforaphane Inhibits the Expression of Long Noncoding RNA H19 and Its Target APOBEC3G and Thereby Pancreatic Cancer Progression

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Zinc Finger Protein CTCF Regulates Extracellular Matrix (ECM)-Related Gene Expression Associated With the Wnt Signaling Pathway in Gastric Cancer

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Mapping of the contraction-induced phosphoproteome identifies TRIM28 as a significant regulator of skeletal muscle size and function

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Vitamin D-regulated gene expression profiles: species-specificity and cell-specific effects on metabolism and immunity

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NADPH oxidase subunit NOXO1 is a target for emphysema treatment in COPD

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Loss of Parkinson’s susceptibility gene LRRK2 promotes carcinogen-induced lung tumorigenesis

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Constitutive activation of cellular immunity underlies the evolution of resistance to infection in Drosophila

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Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression

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The leukocyte non-coding RNA landscape in critically ill patients with sepsis

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Comprehensive Multi-omics Analysis Reveals Mitochondrial Stress as a Central Biological Hub for Spaceflight Impact

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16p11.2 microdeletion imparts transcriptional alterations in human iPSC-derived models of early neural development

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Original research: Long-term survival of patients with stage III colon cancer treated with VRP-CEA(6D), an alphavirus vector that increases the CD8+ effector memory T cell to Treg ratio

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Ablation of Fat Cells in Adult Mice Induces Massive Bone Gain

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Correcting for experiment-specific variability in expression compendia can remove underlying signals

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Fetal HLA-G mediated immune tolerance and interferon response in preeclampsia

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Skeletal Muscle Transcriptomic Comparison between Long-Term Trained and Untrained Men and Women

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Single-Cell Transcriptome Atlas of Murine Endothelial Cells

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Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer

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Combined Targeting of Estrogen Receptor Alpha and Exportin 1 in Metastatic Breast Cancers

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Activin A determines steroid levels and composition in the fetal testis

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GLI transcriptional repression regulates tissue-specific enhancer activity in response to Hedgehog signaling

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Integrated Transcriptome and Network Analysis Reveals Spatiotemporal Dynamics of Calvarial Suturogenesis

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Comprehensive Analysis of Tumor-Infiltrating Immune Cells and Relevant Therapeutic Strategy in Esophageal Cancer

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Osterix-Cre marks distinct subsets of CD45- and CD45+ stromal populations in extra-skeletal tumors with pro-tumorigenic characteristics

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

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Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis

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Genetic Variation in Type 1 Diabetes Reconfigures the 3D Chromatin Organization of T Cells and Alters Gene Expression

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ATR expands embryonic stem cell fate potential in response to replication stress

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Changes in microRNA expression associated with metastasis and survival in patients with uveal melanoma

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The Repertoire of Serous Ovarian Cancer Non-genetic Heterogeneity Revealed by Single-Cell Sequencing of Normal Fallopian Tube Epithelial Cells

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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

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Early epigenetic changes of Alzheimer’s disease in the human hippocampus

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An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

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RAG-Mediated DNA Breaks Attenuate PU.1 Activity in Early B Cells through Activation of a SPIC-BCLAF1 Complex

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Modulation of Microglia by Voluntary Exercise or CSF1R Inhibition Prevents Age-Related Loss of Functional Motor Units

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Dynamic regulation of chromatin accessibility by pluripotency transcription factors across the cell cycle

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  RRID:SCR_010943
  
  DOI: 10.7554/eLife.50087
  
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Proteomic analysis of plasma reveals fat mass influences cancer-related pathways in healthy humans fed controlled diets differing in glycemic load

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  DOI: 10.1158/1940-6207.CAPR-19-0175
  
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Identification of methylation‐driven genes related to prognosis in clear‐cell renal cell carcinoma

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  DOI: 10.1002/jcp.29046
  
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Quantification of Differential Transcription Factor Activity and Multiomics-Based Classification into Activators and Repressors: diffTF

1
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  DOI: 10.1016/j.celrep.2019.10.106
  
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BPS Publications

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  RRID:SCR_010943
  
  DOI: 10.1111/bph.14802
  
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SMUG1 Promotes Telomere Maintenance through Telomerase RNA Processing

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  RRID:SCR_010943
  
  DOI: 10.1016/j.celrep.2019.07.040
  
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Adipocyte Hypoxia-Inducible Factor 2α Suppresses Atherosclerosis by Promoting Adipose Ceramide Catabolism

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  RRID:SCR_010943
  
  DOI: 10.1016/j.cmet.2019.09.016
  
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Liver Is a Generative Site for the B Cell Response to Ehrlichia muris

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  RRID:SCR_010943
  
  DOI: 10.1016/j.immuni.2019.10.004
  
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A Pan-cancer Transcriptome Analysis Reveals Pervasive Regulation through Alternative Promoters

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Key genes associated with diabetes mellitus and hepatocellular carcinoma

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  RRID:SCR_010943
  
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FMRP has a cell-type-specific role in CA1 pyramidal neurons to regulate autism-related transcripts and circadian memory

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  RRID:SCR_010943
  
  DOI: 10.7554/eLife.46919
  
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MUDENG Expression Profiling in Cohorts and Brain Tumor Biospecimens to Evaluate Its Role in Cancer

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  SCR_010943
  
  DOI: 10.3389/fgene.2019.00884
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6763691/
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GPIHBP1 expression in gliomas promotes utilization of lipoprotein-derived nutrients

1
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  SCR_010943
  
  DOI: 10.7554/eLife.47178
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6594755/
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Untitled document

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  RRID:SCR_010943
  
  DOI: 10.1016/j.cell.2019.03.015
  
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Untitled document

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  DOI: 10.1016/j.immuni.2018.12.021
  
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Untitled document

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  DOI: 10.1016/j.celrep.2019.03.093
  
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Untitled document

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  DOI: 10.1002/jcb.28333
  
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Maternal Ribosomes Are Sufficient for Tissue Diversification during Embryonic Development in C. elegans

1
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  DOI: 10.1016/j.devcel.2019.01.019
  
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Natural variation in sugar tolerance associates with changes in signaling and mitochondrial ribosome biogenesis

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  RRID:SCR_010943
  
  DOI: 10.7554/eLife.40841
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6301794/
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Untitled document

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  DOI: 10.1177/1759091419843393
  
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Untitled document

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  DOI: 10.1002/brb3.1258
  
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onlinelibrary.wiley.com/doi/full/10.1002/brb3.1258
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The Crohn’s disease polymorphism, ATG16L1 T300A, alters the gut microbiota and enhances the local Th1/Th17 response

1
1. scibot 12 Jan 2020
  
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  DOI: 10.7554/eLife.39982
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6342529/
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Untitled document

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  DOI: 10.1016/j.celrep.2018.12.087
  
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sciencedirect.com/science/article/pii/S2211124718320473
Apr 2019
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mRNA and microRNA analysis reveals modulation of biochemical pathways related to addiction in the ventral tegmental area of methamphetamine self-administering rats

1
1. scibot 05 Apr 2019
  
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  OMICS_00769
  
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bmcneurosci.biomedcentral.com/articles/10.1186/s12868-015-0186-y
Nov 2018
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Histone Deacetylases 1 and 2 Regulate Microglia Function during Development, Homeostasis, and Neurodegeneration in a Context-Dependent Manner

1
1. scibot 05 Nov 2018
  
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  limma
  
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Genome-Scale Signatures of Gene Interaction from Compound Screens Predict Clinical Efficacy of Targeted Cancer Therapies

1
1. scibot 05 Nov 2018
  
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  Limma
  
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sciencedirect.com/science/article/pii/S2405471218300097
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The Mouse Microbiome Is Required for Sex-Specific Diurnal Rhythms of Gene Expression and Metabolism

1
1. scibot 05 Nov 2018
  
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  Limma
  
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Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

1
1. scibot 05 Nov 2018
  
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  Limma
  
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TFAP2 transcription factors are regulators of lipid droplet biogenesis

1
1. scibot 05 Nov 2018
  
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  LIMMA
  
  Curator: @evieth
  
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Endogenous rRNA Sequence Variation Can Regulate Stress Response Gene Expression and Phenotype

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Epigenetic Restoration of Fetal-like IGF1 Signaling Inhibits Leukemia Stem Cell Activity

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The Xerobranching Response Represses Lateral Root Formation When Roots Are Not in Contact with Water

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LC3-Associated Phagocytosis in Myeloid Cells Promotes Tumor Immune Tolerance

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Quiescent Endothelial Cells Upregulate Fatty Acid β-Oxidation for Vasculoprotection via Redox Homeostasis

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Identification of Therapeutic Targets in Rhabdomyosarcoma through Integrated Genomic, Epigenomic, and Proteomic Analyses

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Decoupling the impact of microRNAs on translational repression versus RNA degradation in embryonic stem cells

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BRG1 governs glucocorticoid receptor interactions with chromatin and pioneer factors across the genome

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onlinelibrary.wiley.com/doi/full/10.1002/brb3.989
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T Cells in Nonlymphoid Tissues Give Rise to Lymph-Node-Resident Memory T Cells

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Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

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A Translational Repression Complex in Developing Mammalian Neural Stem Cells that Regulates Neuronal Specification

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europepmc.org europepmc.org

MELK is not necessary for the proliferation of basal-like breast cancer cells.

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Nov 2017
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A transcriptome‐based assessment of the astrocytic dystrophin‐associated complex in the developing human brain

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onlinelibrary.wiley.com/doi/10.1002/jnr.24082/full
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PP2A Controls Genome Integrity by Integrating Nutrient-Sensing and Metabolic Pathways with the DNA Damage Response

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Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway

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Mex3a Marks a Slowly Dividing Subpopulation of Lgr5+ Intestinal Stem Cells

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Blood transcriptome based biomarkers for human circadian phase

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Fetal and neonatal hematopoietic progenitors are functionally and transcriptionally resistant to Flt3-ITD mutations

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Auxin production in the endosperm drives seed coat development in Arabidopsis

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DNA methylation directs genomic localization of Mbd2 and Mbd3 in embryonic stem cells

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