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  2. 52.53.155.43 52.53.155.43
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    1. scibot 19 Dec 2024
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    2. scibot 19 Dec 2024
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    3. scibot 19 Dec 2024
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  3. Dec 2024
  4. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Reciprocal inhibition of NOTCH and SOX2 shapes tumor cell plasticity and therapeutic escape in triple-negative breast cancer
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    1. scibot 13 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11628624/
  5. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    IFRD1 is required for maintenance of bladder epithelial homeostasis
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    1. scibot 13 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11613175/
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    Biased signaling by mutant EGFR underlies dependence on PKCα in lung adenocarcinoma
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    1. scibot 05 Dec 2024
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    sciencedirect.com/science/article/pii/S2211124724013779
  7. Nov 2024
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High TNF and NF-κB Pathway Dependency Are Associated with AZD5582 Sensitivity in OSCC via CASP8-Dependent Apoptosis
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    1. scibot 13 Nov 2024
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    A comprehensive in silico analysis and experimental validation of miRNAs capable of discriminating between lung adenocarcinoma and squamous cell carcinoma
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    1. scibot 07 Nov 2024
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      DOI: 10.3389/fgene.2024.1419099

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    ncbi.nlm.nih.gov/pmc/articles/PMC11460580/
  10. Oct 2024
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biomarker analyses investigating disease biology and associations with outcomes in the JAVELIN Merkel 200 trial of avelumab in metastatic Merkel cell carcinoma
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    1. scibot 04 Oct 2024
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      DOI: 10.1158/1078-0432.CCR-23-0395

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    ncbi.nlm.nih.gov/pmc/articles/PMC11443199/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oncogenic Calreticulin Induces Immune Escape by Stimulating TGF-β Expression and Regulatory T Cell Expansion in the Bone Marrow Microenvironment
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    1. scibot 02 Oct 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11405138/
  13. Sep 2024
  14. www.sciencedirect.com www.sciencedirect.com
    EDC-3 and EDC-4 regulate embryonic mRNA clearance and biomolecular condensate specialization
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    1. scibot 27 Sep 2024
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      DOI: 10.1016/j.celrep.2024.114781

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    sciencedirect.com/science/article/pii/S221112472401132X
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    Activin A inhibits the migration of human lung adenocarcinoma A549 cells induced by EGF
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    1. scibot 25 Sep 2024
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    sciencedirect.com/science/article/pii/S1567576924016928
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cellular origin and clonal evolution of human dedifferentiated liposarcoma
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    1. scibot 18 Sep 2024
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393420/
  17. www.biorxiv.org www.biorxiv.org
    Spontaneously regenerative corticospinal neurons in mice
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    1. scibot 15 Sep 2024
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      DOI: 10.1101/2024.09.09.612115

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    biorxiv.org/content/10.1101/2024.09.09.612115v1
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    EWS-FLI1 and Activator Protein-1 (AP-1) Reciprocally Regulate Extracellular-Matrix Proteins in Ewing sarcoma Cells
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    1. scibot 13 Sep 2024
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      DOI: 10.3390/ijms25168595

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    ncbi.nlm.nih.gov/pmc/articles/PMC11354993/
  19. Aug 2024
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Concurrent RB1 Loss and BRCA Deficiency Predicts Enhanced Immunologic Response and Long-term Survival in Tubo-ovarian High-grade Serous Carcinoma
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    1. scibot 22 Aug 2024
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  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct tumor-TAM interactions in IDH-stratified glioma microenvironments unveiled by single-cell and spatial transcriptomics
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    1. scibot 22 Aug 2024
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      DOI: 10.1186/s40478-024-01837-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC11328419/
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    Rapid phagosome isolation enables unbiased multiomic analysis of human microglial phagosomes
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    1. scibot 22 Aug 2024
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    sciencedirect.com/science/article/pii/S1074761324003686
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    Novel PAX3::MAML3 fusion identified in alveolar rhabdomyosarcoma, using DNA methylation profiling to expand the genetic spectrum of “fusion-positive” cases
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.modpat.2024.100594

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    sciencedirect.com/science/article/pii/S0893395224001741
  24. www.sciencedirect.com www.sciencedirect.com
    Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions
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    sciencedirect.com/science/article/pii/S2211124724009409
  25. www.biorxiv.org www.biorxiv.org
    The multi-level effect of chlorpyrifos during clownfish metamorphosis
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    1. scibot 20 Aug 2024
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      DOI: 10.1101/2024.08.02.606305

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    biorxiv.org/content/10.1101/2024.08.02.606305v1
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A trade-off in evolution: the adaptive landscape of spiders without venom glands
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    1. scibot 19 Aug 2024
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      DOI: 10.1093/gigascience/giae048

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    ncbi.nlm.nih.gov/pmc/articles/PMC11299198/
  27. Jul 2024
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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      DOI: 10.1158/2767-9764.CRC-23-0428

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    ncbi.nlm.nih.gov/pmc/articles/PMC11270646/
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    Multi-omics profiling to identify early plasma biomarkers in pre-diagnostic pancreatic ductal adenocarcinoma: a nested case-control study
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      DOI: 10.1016/j.tranon.2024.102059

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    sciencedirect.com/science/article/pii/S1936523324001864
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Timing of whole genome duplication is associated with tumor-specific MHC-II depletion in serous ovarian cancer
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      DOI: 10.1038/s41467-024-50137-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11258338/
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    Preclinical study and phase II trial of adapting low-dose radiotherapy to immunotherapy in small cell lung cancer
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      DOI: 10.1016/j.medj.2024.06.002

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    sciencedirect.com/science/article/pii/S2666634024002484
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synaptic plasticity in human thalamocortical assembloids
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    1. scibot 17 Jul 2024
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      DOI: 10.1016/j.celrep.2024.114503

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    ncbi.nlm.nih.gov/pmc/articles/PMC11407288/
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    Mitochondrial perturbation in the intestine causes microbiota-dependent injury and gene signatures discriminative of inflammatory disease
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      DOI: 10.1016/j.chom.2024.06.013

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    sciencedirect.com/science/article/pii/S1931312824002312
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    ABC Efflux Transporters and Solute Carriers in the Early Developing Brain of a Marsupial Monodelphis domestica (South American Gray Short-Tailed Opossum)
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    1. scibot 12 Jul 2024
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      DOI: 10.1002/cne.25655

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    onlinelibrary.wiley.com/doi/full/10.1002/cne.25655
  35. Jun 2024
  36. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide metabolism face-off between macrophages and fibroblasts manipulates the microenvironment in gastric cancer
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      DOI: 10.1016/j.cmet.2024.05.013

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    sciencedirect.com/science/article/pii/S155041312400189X
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Uncovering strain- and age-dependent innate immune responses to SARS-CoV-2 infection in air-liquid-interface cultured nasal epithelia
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      DOI: 10.1016/j.isci.2024.110009

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    ncbi.nlm.nih.gov/pmc/articles/PMC11166695/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Long non-coding RNA TUG1 is downregulated in Friedreich’s ataxia
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    1. scibot 09 Jun 2024
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      DOI: 10.1093/braincomms/fcae170

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    ncbi.nlm.nih.gov/pmc/articles/PMC11154142/
  39. May 2024
  40. www.biorxiv.org www.biorxiv.org
    Distinct Tumor-TAM Interactions in IDH-Stratified Glioma Microenvironments unveiled by Single-Cell and Spatial Transcriptomics
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    1. scibot 31 May 2024
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      DOI: 10.1101/2024.05.23.595505

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    biorxiv.org/content/10.1101/2024.05.23.595505v1
  41. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Modelling atopic dermatitis in healthy human skin for the characterization of topical compounds
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    1. scibot 31 May 2024
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      DOI: 10.1111/exd.15099

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    onlinelibrary.wiley.com/doi/10.1111/exd.15099
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Improving replicability in single-cell RNA-Seq cell type discovery with Dune
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      DOI: 10.1186/s12859-024-05814-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC11127396/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel Spirocyclic Dimer, SpiD3, Targets Chronic Lymphocytic Leukemia Survival Pathways with Potent Preclinical Effects
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      DOI: 10.1158/2767-9764.CRC-24-0071

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    ncbi.nlm.nih.gov/pmc/articles/PMC11110724/
  44. www.sciencedirect.com www.sciencedirect.com
    T-bet deficiency and Hic1 induction override TGF-β-dependency in the formation of CD103+ intestine-resident memory CD8+ T cells
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      DOI: 10.1016/j.celrep.2024.114258

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    sciencedirect.com/science/article/pii/S2211124724005862
  45. www.sciencedirect.com www.sciencedirect.com
    Tuft cell-derived acetylcholine promotes epithelial chloride secretion and intestinal helminth clearance
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    1. scibot 14 May 2024
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      DOI: 10.1016/j.immuni.2024.03.023

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    sciencedirect.com/science/article/pii/S1074761324001444
  46. www.cell.com www.cell.com
    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3′ UTR of FAIM2
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      DOI: 10.1016/j.xgen.2024.100556

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    cell.com/cell-genomics/fulltext/S2666-979X(24)00122-8
  47. Apr 2024
  48. aacrjournals.org aacrjournals.org
    Mesothelin Secretion by Pancreatic Cancer Cells Co-opts Macrophages and Promotes Metastasis
    1
    1. scibot 19 Apr 2024
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      DOI: 10.1158/0008-5472.CAN-23-1542

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    aacrjournals.org/cancerres/article/84/4/527/734130/Mesothelin-Secretion-by-Pancreatic-Cancer-Cells-Co
  49. Mar 2024
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchyme instructs growth while epithelium directs branching in the mouse mammary gland
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      DOI: 10.7554/eLife.93326

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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptome-informed identification and characterisation of Planococcus citri cis- and trans-isoprenyl diphosphate synthase genes
    1
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine-associated genetic variants in NECTIN2 and HPCAL1 are risk factors for abdominal aortic aneurysm
    1
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive blood metabolomics profiling of Parkinson’s disease reveals coordinated alterations in xanthine metabolism
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      DOI: 10.1038/s41531-024-00671-9

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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Cluster of Evolutionarily Recent KRAB Zinc Finger Proteins Protects Cancer Cells from Replicative Stress-Induced Inflammation
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA methylation-environment interactions in the human genome
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      DOI: 10.7554/eLife.89371

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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Estrogen therapy induces receptor-dependent DNA damage enhanced by PARP inhibition in ER+ breast cancer
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single cell transcriptome analysis of the THY-Tau22 mouse model of Alzheimer’s disease reveals sex-dependent dysregulations
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  58. 52.53.155.43 52.53.155.43
    HIV-2 MEDIATED EFFECTS ON TARGET AND BYSTANDER CELLS INDUCE PLASMA PROTEOME REMODELLING
    3
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      DOI: 10.1016/j.isci.2024.109344

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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Patient derived tumoroids of high grade neuroendocrine neoplasms for more personalized therapies
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  60. Feb 2024
  61. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
  62. aacrjournals.org aacrjournals.org
    PHF6-altered T-ALL harbor epigenetic repressive switch at bivalent promoters and respond to 5-azacitidine and venetoclax
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    aacrjournals.org/clincancerres/article/30/1/94/732070/PHF6-altered-T-ALL-Harbor-Epigenetic-Repressive
  63. www.sciencedirect.com www.sciencedirect.com
    An iron rheostat controls hematopoietic stem cell fate
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  64. link.springer.com link.springer.com
    AHRR and SFRP2 in primary versus recurrent high-grade serous ovarian carcinoma and their prognostic implication
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      DOI: 10.1038/s41416-023-02550-1

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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The EstroGene database reveals diverse temporal, context-dependent, and bidirectional estrogen receptor regulomes in breast cancer
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  66. www.sciencedirect.com www.sciencedirect.com
    Specialized replication mechanisms maintain genome stability at human centromeres
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  67. link.springer.com link.springer.com
    Stratifying ICIs-responsive tumor microenvironment in HCC: from parsing out immune-hypoxic crosstalk to clinically applicable MRI-radiomics models
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      DOI: 10.1038/s41416-023-02463-z

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  68. www.biorxiv.org www.biorxiv.org
    A Mutation-driven oncofetal regression fuels phenotypic plasticity in colorectal cancer
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      DOI: 10.1101/2023.12.10.570854

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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acetylation-induced proteasomal degradation of the activated glucocorticoid receptor limits hormonal signaling
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  70. www.nature.com www.nature.com
    A clinically applicable connectivity signature for glioblastoma includes the tumor network driver CHI3L1
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      DOI: 10.1038/s41467-024-45067-8

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  71. link.springer.com link.springer.com
    Investigating metabolic dysregulation in serum of triple transgenic Alzheimer’s disease male mice: implications for pathogenesis and potential biomarkers
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      DOI: 10.1007/s00726-023-03375-1

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  72. www.nature.com www.nature.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
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      DOI: 10.1038/s41598-024-52675-3

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  73. Jan 2024
  74. www.nature.com www.nature.com
    CRISPR/Cas9-mediated deletion of a GA-repeat in human GPM6B leads to disruption of neural cell differentiation from NT2 cells
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRIB3, as a robust prognostic biomarker for HNSC, is associated with poor immune infiltration and cancer cell immune evasion
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      DOI: 10.3389/fimmu.2023.1290839

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  76. aacrjournals.org aacrjournals.org
    Early Cancer Detection in Li-Fraumeni Syndrome with Cell-Free DNA
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    aacrjournals.org/cancerdiscovery/article/14/1/104/732565/Early-Cancer-Detection-in-Li-Fraumeni-Syndrome
  77. www.nature.com www.nature.com
    A new genomic framework to categorize pediatric acute myeloid leukemia
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      DOI: 10.1038/s41588-023-01640-3

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  78. www.sciencedirect.com www.sciencedirect.com
    TDP-43-stratified single-cell proteomics of postmortem human spinal motor neurons reveals protein dynamics in amyotrophic lateral sclerosis
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    β-catenin-driven differentiation is a tissue-specific epigenetic vulnerability in adrenal cancer
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      DOI: 10.1158/0008-5472.CAN-22-2712

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  80. Dec 2023
  81. www.mdpi.com www.mdpi.com
    High Expression of THY1 in Intestinal Gastric Cancer as a Key Factor in Tumor Biology: A Poor Prognosis-Independent Marker Related to the Epithelial–Mesenchymal Transition Profile
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  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulated LAMA3 modulates proliferation, adhesion, migration and epithelial‑to‑mesenchymal transition of cholangiocarcinoma cells
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  83. www.sciencedirect.com www.sciencedirect.com
    Canonical IRE1 function needed to sustain vigorous natural killer cell proliferation during viral infection.
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  84. www.biorxiv.org www.biorxiv.org
    Improving replicability in single-cell RNA-Seq cell type discovery with Dune
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      DOI: 10.1101/2020.03.03.974220

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  85. 52.53.155.43 52.53.155.43
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  86. 52.53.155.43 52.53.155.43
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  87. Nov 2023
  88. www.sciencedirect.com www.sciencedirect.com
    Integration of transcriptomes of senescent cell models with multi-tissue patient samples reveals reduced COL6A3 as an inducer of senescence
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  89. Oct 2023
  90. www.sciencedirect.com www.sciencedirect.com
    Loss of succinyl-CoA synthetase in mouse forebrain results in hypersuccinylation with perturbed neuronal transcription and metabolism
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effect of chronic lithium treatment on hippocampal progenitor cells: Transcriptomic analysis and systems pharmacology
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      DOI: 10.1002/brb3.3215

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting MALAT1 Augments Sensitivity to PARP Inhibition by Impairing Homologous Recombination in Prostate Cancer
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      DOI: 10.1158/2767-9764.CRC-23-0089

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    Comprehensive Analysis of Tumor Microenvironment Reveals Prognostic ceRNA Network Related to Immune Infiltration in Sarcoma
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    Long non-coding RNA TUG1 is down-regulated in Friedreich’s ataxia
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    Immune perturbation network identifies an EMT subtype with chromosomal instability and tumor immune-desert microenvironment
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    Variant-to-function analysis of the childhood obesity chr12q13 locus implicates rs7132908 as a causal variant within the 3’ UTR of FAIM2
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    Diagnosis of childhood febrile illness using a multi-class blood RNA molecular signature
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    DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype
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    Proteomic analysis of the human hippocampus identifies neuronal pentraxin 1 (NPTX1) as synapto-axonal target in late-stage Parkinson's disease
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    Identification of an Imidazopyridine-based Compound as an Oral Selective Estrogen Receptor Degrader for Breast Cancer Therapy
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    Nucleocytoplasmic mRNA redistribution accompanies RNA binding protein mislocalization in ALS motor neurons and is restored by VCP ATPase inhibition
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    Prenatal Δ9-tetrahydrocannabinol exposure in males leads to motivational disturbances related to striatal epigenetic dysregulation
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    Extracellular Vesicle Secretion by Leukemia Cells In Vivo Promotes CLL Progression by Hampering Antitumor T-cell Responses
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    Inter- and intra-tumor heterogeneity of genetic and immune profiles in inherited renal cell carcinoma
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    The diagnostic significance of the ZNF gene family in pancreatic cancer: a bioinformatics and experimental study
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    Microsatellite instability states serve as predictive biomarkers for tumors chemotherapy sensitivity
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    Excess pancreatic elastase alters acinar-β cell communication by impairing the mechano-signaling and the PAR2 pathways
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    NAD + Metabolism Generates a Metabolic Vulnerability in Endocrine-Resistant Metastatic Breast Tumors in Females
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  122. May 2023
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    Evolution of Resistance to Irinotecan in Cancer Cells Involves Generation of Topoisomerase-Guided Mutations in Non-Coding Genome That Reduce the Chances of DNA Breaks
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    Tumor biology and immune infiltration define primary liver cancer subsets linked to overall survival after immunotherapy
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    Classification related to immunogenic cell death predicts prognosis, immune microenvironment characteristics, and response to immunotherapy in lower-grade gliomas
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  132. Apr 2023
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Modeling cross‐talk of RNA modification enzymes reveals tumor microenvironment‐associated clinical significance and immunotherapy prediction in hepatobiliary malignancy
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    Comprehensive epigenomic profiling reveals the extent of disease-specific chromatin states and informs target discovery in ankylosing spondylitis
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    Cancer Cell Resistance to IFNγ Can Occur via Enhanced Double-Strand Break Repair Pathway Activity
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    DNA methylation landscapes of prostate cancer brain metastasis are shaped by early driver genetic alterations
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    A Novel Method for Visualizing In-Vivo Rates of Protein Degradation Provides Insight into how TRIM28 Regulates Muscle Size
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    Elevated enhancer-oncogene contacts and higher oncogene expression levels by recurrent CTCF inactivating mutations in acute T cell leukemia
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    sciencedirect.com/science/article/pii/S2211124723003844
  139. Mar 2023
  140. www.sciencedirect.com www.sciencedirect.com
    SUCNR1 signaling in adipocytes controls energy metabolism by modulating circadian clock and leptin expression
    1
    1. scibot 28 Mar 2023
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      DOI: 10.1016/j.cmet.2023.03.004

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    sciencedirect.com/science/article/pii/S1550413123000827
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of autophagy-related clusters and individual risk model for immunotherapy response prediction in gastric cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC10022822/
  142. www.sciencedirect.com www.sciencedirect.com
    Nicotinamide riboside supplementation is not associated with altered methylation homeostasis in Parkinson’s disease
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      DOI: 10.1016/j.isci.2023.106278

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    sciencedirect.com/science/article/pii/S2589004223003553
  143. www.nature.com www.nature.com
    A noncanonical response to replication stress protects genome stability through ROS production, in an adaptive manner
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      DOI: 10.1038/s41418-023-01141-0

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    nature.com/articles/s41418-023-01141-0
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated, Longitudinal Analysis of Cell-free DNA in Uveal Melanoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9973415/
  145. Feb 2023
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide epigenetic and mRNA-expression profiling followed by CRISPR/Cas9-mediated gene-disruptions corroborate the MIR141/MIR200C-ZEB1/ZEB2-FGFR1 axis in acquired EMT-associated EGFR TKI-resistance in NSCLC cells
    1
    1. scibot 11 Feb 2023
      RRID:SCR_010943

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    ncbi.nlm.nih.gov/pmc/articles/PMC9903082/
  147. aacrjournals.org aacrjournals.org
    Plk1 Inhibitors and Abiraterone Synergistically Disrupt Mitosis and Kill Cancer Cells of Disparate Origin Independently of Androgen Receptor Signaling
    1
    1. scibot 10 Feb 2023
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      DOI: 10.1158/0008-5472.CAN-22-1533

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    aacrjournals.org/cancerres/article/83/2/219/715076/Plk1-Inhibitors-and-Abiraterone-Synergistically
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Genomic Analysis Identifies UBTF Tandem Duplications as a Recurrent Lesion in Pediatric Acute Myeloid Leukemia
    1
    1. scibot 09 Feb 2023
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      DOI: 10.1158/2643-3230.BCD-21-0160

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    ncbi.nlm.nih.gov/pmc/articles/PMC9780084/
  149. www.sciencedirect.com www.sciencedirect.com
    Single-cell RNA-seq analysis reveals dual sensing of HIV-1 in blood Axl+ dendritic cells
    1
    1. scibot 04 Feb 2023
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      DOI: 10.1016/j.isci.2023.106019

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    sciencedirect.com/science/article/pii/S2589004223000962
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DDR2 coordinates EMT and metabolic reprogramming as a shared effector of FOXQ1 and SNAI1
    1
    1. scibot 01 Feb 2023
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      DOI: 10.1158/2767-9764.crc-22-0013

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    ncbi.nlm.nih.gov/pmc/articles/PMC9881645/
  151. Jan 2023
  152. www.sciencedirect.com www.sciencedirect.com
    IGF1 deficiency integrates stunted growth and neurodegeneration in Down syndrome
    1
    1. scibot 28 Jan 2023
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    sciencedirect.com/science/article/pii/S221112472201779X
  153. www.sciencedirect.com www.sciencedirect.com
    Enrichment of oral-derived bacteria in inflamed colorectal tumors and distinct associations of Fusobacterium in the mesenchymal subtype
    1
    1. scibot 27 Jan 2023
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      DOI: 10.1016/j.xcrm.2023.100920

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    sciencedirect.com/science/article/pii/S2666379123000058
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systems level analysis of sex-dependent gene expression changes in Parkinson’s disease
    1
    1. scibot 25 Jan 2023
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      DOI: 10.1038/s41531-023-00446-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC9867746/
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Genome-wide screen identifies PDPK1 as a target to enhance the efficacy of MEK1/2 inhibitors in NRAS mutant melanoma
    1
    1. scibot 20 Jan 2023
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      DOI: 10.1158/0008-5472.CAN-21-3217

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    ncbi.nlm.nih.gov/pmc/articles/PMC9298960/
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human Papillomavirus 42 Drives Digital Papillary Adenocarcinoma and Elicits a Germ Cell–like Program Conserved in HPV-Positive Cancers
    1
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      DOI: 10.1158/2159-8290.CD-22-0489

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    ncbi.nlm.nih.gov/pmc/articles/PMC9827110/
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Low-Dose Radiotherapy Reverses Tumor Immune Desertification and Resistance to Immunotherapy
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      DOI: 10.1158/2159-8290.CD-21-0003

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    ncbi.nlm.nih.gov/pmc/articles/PMC9401506/
  158. Dec 2022
  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting metabolic adaptations in the breast cancer–liver metastatic niche using dietary approaches to improve endocrine therapy efficacy
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      DOI: 10.1158/1541-7786.MCR-21-0781

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    ncbi.nlm.nih.gov/pmc/articles/PMC9177734/
  160. Nov 2022
  161. www.sciencedirect.com www.sciencedirect.com
    Tip60-mediated H2A.Z acetylation promotes neuronal fate specification and bivalent gene activation
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    1. scibot 24 Nov 2022
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      DOI: 10.1016/j.molcel.2022.11.002

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    sciencedirect.com/science/article/abs/pii/S1097276522010644
  162. aacrjournals.org aacrjournals.org
    DDR2 Coordinates EMT and Metabolic Reprogramming as a Shared Effector of FOXQ1 and SNAI1
    1
    1. scibot 16 Nov 2022
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      DOI: 10.1158/2767-9764.CRC-22-0013

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    aacrjournals.org/cancerrescommun/article/2/11/1388/710518/DDR2-Coordinates-EMT-and-Metabolic-Reprogramming
  163. link.springer.com link.springer.com
    The LncRNA MIAT is identified as a regulator of stemness-associated transcript in glioma
    1
    1. scibot 10 Nov 2022
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      DOI: 10.1007/s11033-022-07962-5

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  164. www.sciencedirect.com www.sciencedirect.com
    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
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    sciencedirect.com/science/article/pii/S2211124722013328
  165. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant Samd9l expression impairs hematopoiesis and induces bone marrow failure in mice
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      DOI: 10.1172/JCI158869

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    ncbi.nlm.nih.gov/pmc/articles/PMC9621136/
  166. Oct 2022
  167. www.sciencedirect.com www.sciencedirect.com
    Circadian transcriptional pathway atlas highlights a proteasome switch in intermittent fasting
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    sciencedirect.com/science/article/pii/S2211124722014036
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2-dependent glutaminolysis pathway
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    1. scibot 26 Oct 2022
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      DOI: 10.1126/sciadv.abq0117

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  169. alzres.biomedcentral.com alzres.biomedcentral.com
    Gossypetin ameliorates 5xFAD spatial learning and memory through enhanced phagocytosis against Aβ
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      DOI: 10.1186/s13195-022-01096-3

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    alzres.biomedcentral.com/articles/10.1186/s13195-022-01096-3
  170. www.science.org www.science.org
    Mitochondrial pyruvate supports lymphoma proliferation by fueling a glutamate pyruvate transaminase 2–dependent glutaminolysis pathway
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      DOI: 10.1126/sciadv.abq0117

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  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct biomarker profiles and TCR sequence diversity characterize the response to PD-L1 blockade in a mouse melanoma model
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      DOI: 10.1158/1541-7786.MCR-20-0881

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    ncbi.nlm.nih.gov/pmc/articles/PMC9533714/
  172. www.sciencedirect.com www.sciencedirect.com
    A cis-regulatory lexicon of DNA motif combinations mediating cell-type-specific gene regulation
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      DOI: 10.1016/j.xgen.2022.100191

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    sciencedirect.com/science/article/pii/S2666979X22001409
  173. Sep 2022
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Biological misinterpretation of transcriptional signatures in tumor samples can unknowingly undermine mechanistic understanding and faithful alignment with preclinical data
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      DOI: 10.1158/1078-0432.CCR-22-1102

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  175. www.sciencedirect.com www.sciencedirect.com
    A small proportion of X-linked genes contribute to X chromosome upregulation in early embryos via BRD4-mediated transcriptional activation
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      DOI: 10.1016/j.cub.2022.08.059

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  176. www.sciencedirect.com www.sciencedirect.com
    Artificial gravity partially protects space-induced neurological deficits in Drosophila melanogaster
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  177. Aug 2022
  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating microRNA: Myocardium-derived prenatal biomarker of ventricular septal defects
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      DOI: 10.3389/fgene.2022.899034

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    ncbi.nlm.nih.gov/pmc/articles/PMC9403759/
  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Race-associated molecular changes in gynecologic malignancies
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    ncbi.nlm.nih.gov/pmc/articles/PMC9390975/
  180. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of CXCL10 and CXCL11 as the candidate genes involving the development of colitis-associated colorectal cancer
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      DOI: 10.3389/fgene.2022.945414

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  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mapping of m6A and Its Regulatory Targets in Prostate Cancer Reveals a METTL3-low Induction of Therapy Resistance
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      DOI: 10.1158/1541-7786.MCR-21-0014

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  182. Jun 2022
  183. 52.53.155.43 52.53.155.43
    KCa3.1 differentially regulates trachea and bronchi epithelial gene expression in a chronic-asthma mouse model
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      DOI: 10.1152/physiolgenomics.00134.2021

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  184. www.sciencedirect.com www.sciencedirect.com
    MacroH2As regulate enhancer-promoter contacts affecting enhancer activity and sensitivity to inflammatory cytokines
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  185. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial cyclophilin D promotes disease tolerance by licensing NK cell development and IL-22 production against influenza virus
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  186. aacrjournals.org aacrjournals.org
    Phosphorylation of SHP2 at Tyr62 enables acquired resistance to SHP2 allosteric inhibitors in FLT3-ITD-driven AML
    1
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      DOI: 10.1158/0008-5472.CAN-21-0548

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  187. May 2022
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    Regionally defined proteomic profiles of human cerebral tissue and organoids reveal conserved molecular modules of neurodevelopment
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    BMAL1 modulates smooth muscle cells phenotypic switch towards fibroblast-like cells and stabilizes atherosclerotic plaques by upregulating YAP1
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    Tumor ENPP1(CD203a)/Haptoglobin Axis Exploits Myeloid-Derived Suppressor Cells to Promote Post-Radiotherapy Local Recurrence in Breast Cancer
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    Cytoplasmic proteotoxicity regulates HRI-dependent phosphorylation of eIF2α via the Hsp70-Bag3 module
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    Sex disparities in influenza: A multiscale network analysis
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    Lactate rewires lipid metabolism and sustains a metabolic-epigenetic axis in prostate cancer
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    Tenascin-C can Serve as an Indicator for the Immunosuppressive Microenvironment of Diffuse Low-Grade Gliomas
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  198. Mar 2022
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    Novel insights from a multiomics dissection of the Hayflick limit
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    Characterizing gene expression in an&nbsp;<i>in vitro</i> biomechanical strain model of joint health
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    Race-associated Molecular Changes in Gynecologic Malignancies
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  202. Feb 2022
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    FMRP regulates mRNAs encoding distinct functions in the cell body and dendrites of CA1 pyramidal neurons
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    Genetic Liability for Internalizing Versus Externalizing Behavior Manifests in the Developing and Adult Hippocampus: Insight From a Meta-analysis of Transcriptional Profiling Studies in a Selectively Bred Rat Model
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    Mediator of DNA damage checkpoint 1 (MDC1) is a novel estrogen receptor co-regulator in invasive lobular carcinoma of the breast
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  207. Jan 2022
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    Genomic loci mispositioning in Tmem120a knockout mice yields latent lipodystrophy
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  210. Dec 2021
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    Role of miR-2392 in driving SARS-CoV-2 infection
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  219. Sep 2021
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    Subventricular zone/white matter microglia reconstitute the empty adult microglial niche in a dynamic wave
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    An engineered transcriptional reporter of protein localization identifies regulators of mitochondrial and ER membrane protein trafficking in high-throughput CRISPRi screens
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    Functional impairment of HIV-specific CD8+ T cells precedes aborted spontaneous control of viremia
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    Optimized CRISPR-mediated gene knockin reveals FOXP3-independent maintenance of human Treg identity
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    Evolution of reduced co-activator dependence led to target expansion of a starvation response pathway
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