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2,057 Matching Annotations

Sep 2023
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MATR3 is an endogenous inhibitor of DUX4 in FSHD muscular dystrophy

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1. scibot 14 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113120
  
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sciencedirect.com/science/article/pii/S2211124723011324
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A NRF2 inhibitor selectively sensitizes KEAP1 mutant tumor cells to cisplatin and gefitinib by restoring NRF2-inhibitory function of KEAP1 mutants

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1. scibot 14 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113104
  
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sciencedirect.com/science/article/pii/S2211124723011154
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CHIP protects against septic acute kidney injury by inhibiting NLRP3-mediated pyroptosis

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1. scibot 12 Sep 2023
  
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  DOI: 10.1016/j.isci.2023.107762
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10492219/
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Mechanism and evolutionary origins of alanine-tail C-degron recognition by E3 ligases Pirh2 and CRL2-KLHDC10

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1. scibot 08 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113100
  
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sciencedirect.com/science/article/pii/S2211124723011117
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A co-opted endogenous retroviral envelope promotes cell survival by controlling CTR1-mediated copper transport and homeostasis

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  DOI: 10.1016/j.celrep.2023.113065
  
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sciencedirect.com/science/article/pii/S2211124723010768
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CHCHD2 Thr61Ile mutation impairs F1F0-ATPase assembly in in vitro and in vivo models of Parkinson’s disease

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1. scibot 07 Sep 2023
  
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  DOI: 10.4103/1673-5374.378010
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10479855/
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Anillin forms linear structures and facilitates furrow ingression after septin and formin depletion

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.celrep.2023.113076
  
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sciencedirect.com/science/article/pii/S2211124723010872
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Structural basis of CD97 activation and G-protein coupling

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1. scibot 07 Sep 2023
  
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  DOI: 10.1016/j.chembiol.2023.08.003
  
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cell.com/cell-chemical-biology/fulltext/S2451-9456(23)00275-1
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Plk2 promotes synaptic destabilization through disruption of N-cadherin adhesion complexes during homeostatic adaptation to hyperexcitation

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1. scibot 06 Sep 2023
  
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  DOI: 10.1111/jnc.15948
  
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onlinelibrary.wiley.com/doi/10.1111/jnc.15948
Aug 2023
pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov

Mechanical stimulation from the surrounding tissue activates mitochondrial energy metabolism in Drosophila differentiating germ cells

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1. scibot 30 Aug 2023
  
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  DOI: 10.1016/j.devcel.2023.08.007
  
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pmc.ncbi.nlm.nih.gov/articles/PMC10843713/
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Efficient genome editing in erythroid cells unveils novel MYB target genes and regulatory functions

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1. scibot 27 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107641
  
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sciencedirect.com/science/article/pii/S2589004223017182
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MARCH7-mediated ubiquitination decreases the solubility of ATG14 to inhibit autophagy

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1. scibot 27 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113045
  
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sciencedirect.com/science/article/pii/S2211124723010562
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Hypermethylation of RNF125 promotes autophagy-induced oxidative stress in asthma by increasing HMGB1 stability

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1. scibot 26 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107503
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10432822/
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A split-luciferase lysate-based approach to identify small-molecule modulators of phosphatase subunit interactions

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1. scibot 25 Aug 2023
  
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  DOI: 10.1016/j.chembiol.2023.07.018
  
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sciencedirect.com/science/article/pii/S2451945623002428
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Different mechanisms of synapsin-induced vesicle clustering at inhibitory and excitatory synapses

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1. scibot 23 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.113004
  
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sciencedirect.com/science/article/pii/S221112472301015X
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TRAF7 is an essential regulator of blood vessel integrity during mouse embryonic and neonatal development

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1. scibot 19 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107474
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10424150/
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Loss of CtBP2 may be a mechanistic link between metabolic derangements and progressive impairment of pancreatic β cell function

2
1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112914
  
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2. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112914
  
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52.53.155.43/464fcb14db36fa0ad68672734eea21dbff7f105c/PIIS2211124723009257-html.html
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PIIS221112472300952X-html.html

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112941
  
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52.53.155.43/1abfd5fba02bda950654c5dfd88ce712e0bc4f04/PIIS221112472300952X-html.html
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PIIS2589004223017029-html.html

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  DOI: 10.1016/j.isci.2023.107625
  
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52.53.155.43/258d74bd1c79cf4d725c254c0f9188b69c056c90/PIIS2589004223017029-html.html
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E4 ubiquitin ligase promotes mitofusin turnover and mitochondrial stress response

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.molcel.2023.07.021
  
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sciencedirect.com/science/article/pii/S1097276523005634
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A conserved family of immune effectors cleaves cellular ATP upon viral infection

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1. scibot 18 Aug 2023
  
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  DOI: 10.1016/j.cell.2023.07.020
  
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sciencedirect.com/science/article/abs/pii/S0092867423007973
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LHPP-mediated inorganic pyrophosphate hydrolysis-driven lysosomal acidification in astrocytes regulates adult neurogenesis

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112975
  
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  DOI: 10.1016/j.celrep.2023.112975
  
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Protocol to assess receptor-ligand binding in C. elegans using adapted thermal shift assays

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1. scibot 16 Aug 2023
  
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  DOI: 10.1016/j.xpro.2023.102477
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10415787/
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Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis

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1. scibot 12 Aug 2023
  
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  DOI: 10.1126/sciadv.adf6895
  
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science.org/doi/10.1126/sciadv.adf6895
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Increased SIRT3 combined with PARP inhibition rescues motor function of SBMA mice

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.isci.2023.107375
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10433013/
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Cooperative assembly confers regulatory specificity and long-term genetic circuit stability

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1. scibot 10 Aug 2023
  
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  DOI: 10.1016/j.cell.2023.07.012
  
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sciencedirect.com/science/article/pii/S0092867423007456
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Monomerization of TDP-43 is a key determinant for inducing TDP-43 pathology in amyotrophic lateral sclerosis

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1. scibot 10 Aug 2023
  
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  DOI: 10.1126/sciadv.adf6895
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10403219/
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Art2 mediates selective endocytosis of methionine transporters during adaptation to sphingolipid depletion

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1. scibot 05 Aug 2023
  
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  DOI: 10.1242/jcs.260675
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10399987/
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High-throughput functional characterization of combinations of transcriptional activators and repressors

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1. scibot 05 Aug 2023
  
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  DOI: 10.1016/j.cels.2023.07.001
  
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sciencedirect.com/science/article/abs/pii/S2405471223001862
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Phase-separated nuclear bodies of nucleoporin fusions promote condensation of MLL1/CRM1 and rearrangement of 3D genome structure

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112884
  
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sciencedirect.com/science/article/pii/S2211124723008951
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DPPA3-HIF1α axis controls colorectal cancer chemoresistance by imposing a slow cell-cycle phenotype

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1. scibot 03 Aug 2023
  
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  DOI: 10.1016/j.celrep.2023.112927
  
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sciencedirect.com/science/article/pii/S2211124723009385
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PRMT4 Facilitates White Adipose Tissue Browning and Thermogenesis by Methylating PPARγ

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1. scibot 02 Aug 2023
  
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  DOI: 10.2337/db22-1016
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10382653/
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Heroin Self-Administration and Extinction Increase Prelimbic Cortical Astrocyte–Synapse Proximity and Alter Dendritic Spine Morphometrics That Are Reversed by N-Acetylcysteine

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1. scibot 01 Aug 2023
  
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  DOI: 10.3390/cells12141812
  
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ncbi.nlm.nih.gov/pmc/articles/PMC10378353/
Jul 2023
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Phosphatidylinositol 3-phosphate regulates iron transport via PI3P-binding CgPil1 protein

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1. scibot 27 Jul 2023
  
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  DOI: 10.1016/j.celrep.2023.112855
  
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Clinically Defined Mutations in MEN1 Alter Its Tumor-suppressive Function Through Increased Menin Turnover

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Banana MKK1 modulates fruit ripening via the MKK1-MPK6-3/11-4-bZIP21 module

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Visualization of direct and diffusion-assisted RAD51 nucleation by full-length human BRCA2 protein

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Cancer cell employs a microenvironmental neural signal trans-activating nucleus-mitochondria coordination to acquire stemness

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Poly(GR) interacts with key stress granule factors promoting its assembly into cytoplasmic inclusions

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Phosphoribosyl-linked serine ubiquitination of USP14 by the SidE family effectors of Legionella excludes p62 from the bacterial phagosome

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Orphan quality control shapes network dynamics and gene expression

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Apical polarity and actomyosin dynamics regulate Hippo signaling by controlling Kibra subcellular localization

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Elevated FBXW10 drives hepatocellular carcinoma tumorigenesis via AR-VRK2 phosphorylation-dependent GAPDH ubiquitination in male transgenic mice

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Customization of the translational complex regulates mRNA-specific translation to control CNS regeneration

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The oxidative folding of nascent polypeptides provides electrons for reductive reactions in the ER

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Sen1 and Rrm3 ensure permissive topological conditions for replication termination

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Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1

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Transcriptional metabolic reprogramming implements meiotic fate decision in mouse testicular germ cells

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IFITM1 inhibits trophoblast invasion and is induced in placentas associated with IFN-mediated pregnancy diseases

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Delineation of functional subdomains of Huntingtin protein and their interaction with HAP40

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4405.full-html.html

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Convergence of multiple RNA-silencing pathways on GW182/TNRC6

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The nucleotide receptor STING translocates to the phagosomes to negatively regulate anti-fungal immunity

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Non-muscle MYH10/myosin IIB recruits ESCRT-III to participate in autophagosome closure to maintain neuronal homeostasis

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16p11.2 CNV gene Doc2α functions in neurodevelopment and social behaviors through interaction with Secretagogin

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KIBRA repairs synaptic plasticity and promotes resilience to tauopathy-related memory loss

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SMYD3 induces sorafenib resistance by activating SMAD2/3-mediated epithelial-mesenchymal transition in hepatocellular carcinoma

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Cooperative sensing of mitochondrial DNA by ZBP1 and cGAS promotes cardiotoxicity

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Histone H3 lysine 27 crotonylation mediates gene transcriptional repression in chromatin

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Phosphatidylinositol 4-kinase IIα is a glycogen synthase kinase 3-regulated interaction hub for activity-dependent bulk endocytosis

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A mitochondrial iron-responsive pathway regulated by DELE1

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Gasdermin D licenses MHCII induction to maintain food tolerance in small intestine

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ARS2 instructs early transcription termination-coupled RNA decay by recruiting ZC3H4 to nascent transcripts

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A Golgi-resident GPR108 cooperates with E3 ubiquitin ligase Smurf1 to suppress antiviral innate immunity

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Non-canonical role of UCKL1 on ferroptosis defence in colorectal cancer

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Aclarubicin stimulates RNA polymerase II elongation at closely spaced divergent promoters

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Restored autophagy is protective against PAK3-induced cardiac dysfunction

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Endogenous PP2A inhibitor CIP2A degradation by chaperone-mediated autophagy contributes to the antitumor effect of mitochondrial complex I inhibition

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Enterohemorrhagic Escherichia coli senses microbiota-derived nicotinamide to increase its virulence and colonization in the large intestine

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Comprehensive Interactome Mapping of the DNA Repair Scaffold SLX4 Using Proximity Labeling and Affinity Purification

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LZTR1 mutation mediates oncogenesis through stabilization of EGFR and AXL

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A new Karyopherin-β2 binding PY-NLS epitope of HNRNPH2 linked to neurodevelopmental disorders

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Human Tim8a, Tim8b and Tim13 are auxiliary assembly factors of mature Complex IV

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A Tumor-suppressive Molecular Axis EP300/circRERE/miR-6837-3p/MAVS Activates Type I IFN Pathway and Antitumor Immunity to Suppress Colorectal Cancer

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SETD7 promotes lateral plate mesoderm formation by modulating the Wnt/β-catenin signaling pathway

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Ferroptosis surveillance independent of GPX4 and differentially regulated by sex hormones

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Alternative splicing of GSDMB modulates killer lymphocyte–triggered pyroptosis

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Deneddylating enzyme SENP8 regulates neuronal development

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The SphK1/S1P axis regulates synaptic vesicle endocytosis via TRPC5 channels

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IL-1β-associated NNT acetylation orchestrates iron-sulfur cluster maintenance and cancer immunotherapy resistance

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RBM33 is a unique m6A RNA-binding protein that regulates ALKBH5 demethylase activity and substrate selectivity

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s11684-022-0959-5-html.html

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A Wnt-induced lncRNA-DGCR5 splicing switch drives tumor-promoting inflammation in esophageal squamous cell carcinoma

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Integrative transcriptomics and cell systems analyses reveal protective pathways controlled by Igfbp-3 in anthracycline-induced cardiotoxicity

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PROX1 induction by autolysosomal activity stabilizes persister-like state of colon cancer via feedback repression of the NOX1-mTORC1 pathway

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Human DUX4 and mouse Dux interact with STAT1 and broadly inhibit interferon-stimulated gene induction

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A LY6E-PHB1-TRIM21 assembly degrades CD14 protein to mitigate LPS-induced inflammatory response

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Glutamate-releasing BEST1 channel is a new target for neuroprotection against ischemic stroke with wide time window

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The mitochondrial intermembrane space protein mitofissin drives mitochondrial fission required for mitophagy

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Methylated histones on mitotic chromosomes promote Topoisomerase IIα function for high fidelity chromosome segregation.

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CKB regulates BCAR1 phosphorylation to facilitate DNA damage repair

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Protein quality control machinery supports primary ciliogenesis by eliminating GDP-bound Rab8-family GTPases

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Vitamin K-dependent carboxylation regulates Ca2+ flux and adaptation to metabolic stress in β cells

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Bat ASC2 suppresses inflammasomes and ameliorates inflammatory diseases

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Calcineurin associates with centrosomes and regulates cilia length maintenance

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DUSP4 promotes esophageal squamous cell carcinoma progression by dephosphorylating HSP90β

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The ubiquitin-ligase TRAF6 and TGFβ type I receptor form a complex with Aurora kinase B contributing to mitotic progression and cytokinesis in cancer cells

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Compounds activating VCP D1 ATPase enhance both autophagic and proteasomal neurotoxic protein clearance

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Organism-wide, cell-type-specific secretome mapping of exercise training in mice

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Stress granule formation inhibits stress-induced apoptosis by selectively sequestering executioner caspases

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Microglial-to-neuronal CCR5 signaling regulates autophagy in neurodegeneration

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BPS Publications

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UTP18-mediated p21 mRNA instability drives adenoma-carcinoma progression in colorectal cancer

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Integrative genetic analysis identifies FLVCR1 as a plasma-membrane choline transporter in mammals

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Ctnnb1/β-catenin inactivation in UCP1-positive adipocytes augments the browning of white adipose tissue

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Germline and somatic inactivating FLCN variants in parathyroid cancer and atypical parathyroid tumors

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The mechanism of STING autoinhibition and activation

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Gαs slow conformational transition upon GTP binding and a novel Gαs regulator

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Proteomic discovery of chemical probes that perturb protein complexes in human cells

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Engineered Escherichia coli for the in situ secretion of therapeutic nanobodies in the gut

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Coronavirus Subverts ER-phagy by Hijacking FAM134B and ATL3 into p62 Condensates to Facilitate Viral Replication

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A proinsulin-dependent interaction between ENPL-1 and ASNA-1 in neurons is required to maintain insulin secretion in C. elegans

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ER-localized JmjC domain-containing protein JMJD8 targets STING to promote immune evasion and tumor growth in breast cancer

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Ecdysone signaling determines lateral polarity and remodels neurites to form Drosophila’s left-right brain asymmetry

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X-chromosome target specificity diverged between dosage compensation mechanisms of two closely related Caenorhabditis species

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Structural and functional properties of mSWI/SNF chromatin remodeling complexes revealed through single-cell perturbation screens

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PYHIN protein IFI207 regulates cytokine transcription and IRF7 and contributes to the establishment of K. pneumoniae infection

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SLFN5-mediated chromatin dynamics sculpt higher-order DNA repair topology

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Newly synthesized AIFM1 determines the hypersensitivity of T lymphocytes to STING activation-induced cell apoptosis

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The ancestral ESCRT protein TOM1L2 selects ubiquitinated cargoes for retrieval from cilia

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TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells

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TZAP overexpression induces telomere dysfunction and ALT-like activity in ATRX/DAXX deficient cells

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Neofunctionalisation of ciliary BBS proteins to nuclear roles is likely a frequent innovation across eukaryotes

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Proteasome Inhibitors Silence Oncogenes in Multiple Myeloma through Localized Histone Deacetylase 3 Stabilization and Chromatin Condensation

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Characterisation of the OTU domain deubiquitinase complement of Toxoplasma gondii

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Capture RIC-seq reveals positional rules of PTBP1-associated RNA loops in splicing regulation

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PQBP1 regulates striatum development through balancing striatal progenitor proliferation and differentiation

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An optimized protocol to detect protein ubiquitination and activation by ubiquitination assay in vivo and CCK-8 assay

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Proximity labeling reveals OTUD3 as a DNA-binding deubiquitinase of cGAS

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Topological regulation of a transmembrane protein by luminal-to-cytosolic retrotranslocation of glycosylated sequence

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The ubiquitin E3 ligase TRIM10 promotes STING aggregation and activation in the Golgi apparatus

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A single-copy knockin translating ribosome immunoprecipitation toolkit for tissue-specific profiling of actively translated mRNAs in C. elegans

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Structural basis for the Rad6 activation by the Bre1 N-terminal domain

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Characterization of the Tau Interactome in Human Brain Reveals Isoform-Dependent Interaction with 14-3-3 Family Proteins

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Nutrigenomic regulation of sensory plasticity

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Activation of AMP-activated protein kinase (AMPK) through inhibiting interaction with prohibitins

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A central chaperone-like role for 14-3-3 proteins in human cells

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Deficiency of WTAP in islet beta cells results in beta cell failure and diabetes in mice

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The tetraspan LHFPL5 is critical to establish maximal force sensitivity of the mechanotransduction channel of cochlear hair cells

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A combinatorial approach to uncover an additional Integrator subunit

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Recruitment of Polo-like kinase couples synapsis to meiotic progression via inactivation of CHK-2

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Acetylated HOXB13 Regulated Super Enhancer Genes Define Therapeutic Vulnerabilities of Castration-Resistant Prostate Cancer

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LMAN1 is a receptor for house dust mite allergens

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Cell context-dependent CFI-1/ARID3 functions control neuronal terminal differentiation

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FAM193A is a positive regulator of p53 activity

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Lysosomal trafficking of the glucose transporter GLUT1 requires sequential regulation by TXNIP and ubiquitin

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An AlphaFold2 map of the 53BP1 pathway identifies a direct SHLD3-RIF1 interaction critical for DNA repair activity

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Mutant NPM1 Hijacks Transcriptional Hubs to Maintain Pathogenic Gene Programs in Acute Myeloid Leukemia

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JMJ28 guides sequence-specific targeting of ATX1/2-containing COMPASS-like complex in Arabidopsis

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METTL16 promotes translation and lung tumorigenesis by sequestering cytoplasmic eIF4E2

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Linking chromatin acylation mark-defined proteome and genome in living cells

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BPS Publications

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Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module

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Phosphoenolpyruvate regulates the Th17 transcriptional program and inhibits autoimmunity

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FAK-mediated phosphorylation at Y464 regulates p85β nuclear translocation to promote tumorigenesis of ccRCC by repressing RB1 expression

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Regulation of cargo exocytosis by a Reps1-Ralbp1-RalA module

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Epigenetic function during heroin self-administration controls future relapse-associated behavior in a cell type-specific manner

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PIMT regulates Hepatic Gluconeogenesis in Mice

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Chemical inhibition of mitochondrial fission via targeting the DRP1-receptor interaction

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Evolutionary origins and interactomes of human, young microproteins and small peptides translated from short open reading frames

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Global translational induction during NLR-mediated immunity in plants is dynamically regulated by CDC123, an ATP-sensitive protein

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NRF3 activates mTORC1 arginine-dependently for cancer cell viability

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Non-canonical pattern recognition of a pathogen-derived metabolite by a nuclear hormone receptor identifies virulent bacteria in C. elegans

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Scaffold coupling: ERK activation by trans-phosphorylation across different scaffold protein species

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STRA6 promotes thyroid carcinoma progression via activation of the ILK/AKT/mTOR axis in cells and female nude mice

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cd-22-0376-html.html

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Nitric oxide suppression by secreted frizzled-related protein 2 drives retinoblastoma

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Molecular basis of eIF5A-dependent CAT tailing in eukaryotic ribosome-associated quality control

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Human hematopoietic stem cell vulnerability to ferroptosis

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A concerted mechanism involving ACAT and SREBPs by which oxysterols deplete accessible cholesterol to restrict microbial infection

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Allosteric inhibition of HSP70 in collaboration with STUB1 augments enzalutamide efficacy in antiandrogen resistant prostate tumor and patient-derived models

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Pluripotency retention and exogenous mRNA introduction in planarian stem cells in culture

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Diverse CMT2 neuropathies are linked to aberrant G3BP interactions in stress granules

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An affinity-directed phosphatase, AdPhosphatase, system for targeted protein dephosphorylation

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sciencedirect.com/science/article/pii/S2451945623000260
Jan 2023
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The lipid transporter ORP2 regulates synaptic neurotransmitter release via two distinct mechanisms

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  DOI: 10.1016/j.celrep.2022.111882
  
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Fungal CFEM effectors negatively regulate a maize wall-associated kinase by interacting with its alternatively spliced variant to dampen resistance

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  DOI: 10.1016/j.celrep.2022.111877
  
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cell.com/cell-reports/fulltext/S2211-1247(22)01773-9
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Mitochondrial SENP2 regulates the assembly of SDH complex under metabolic stress

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  DOI: 10.1016/j.celrep.2023.112041
  
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BRPF1 bridges H3K4me3 and H3K23ac in human ESCs and is essential to pluripotency

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  DOI: 10.1016/j.isci.2023.105939
  
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Higher-order SPOP assembly reveals a basis for cancer mutant dysregulation

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SUMOylation of HNRNPA2B1 modulates RPA dynamics during unperturbed replication and genotoxic stress responses

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  DOI: 10.1016/j.molcel.2023.01.003
  
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SAYSD1 senses UFMylated ribosome to safeguard co-translational protein translocation at the endoplasmic reticulum

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Ventral tegmental area astrocytes modulate cocaine reward by tonically releasing GABA

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Protocol to measure centrosome cohesion deficits mediated by pathogenic LRRK2 in cultured cells using confocal microscopy

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  DOI: 10.1016/j.xpro.2022.102024
  
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The NLRP1 and CARD8 inflammasomes detect reductive stress

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The interferon stimulated gene-encoded protein HELZ2 inhibits human LINE-1 retrotransposition and LINE-1 RNA-mediated type I interferon induction

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  DOI: 10.1038/s41467-022-35757-6
  
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Disrupting the ciliary gradient of active Arl3 affects rod photoreceptor nuclear migration

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Human SMARCA5 is continuously required to maintain nucleosome spacing

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  DOI: 10.1016/j.molcel.2022.12.018
  
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The TAZ-CAMTA1 Fusion Protein Promotes Tumorigenesis via Connective Tissue Growth Factor and Ras–MAPK Signaling in Epithelioid Hemangioendothelioma

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Novel Calcium-Binding Ablating Mutations Induce Constitutive RET Activity and Drive Tumorigenesis

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  DOI: 10.1158/0008-5472.CAN-22-0834
  
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Evolutionarily conserved regulators of tau identify targets for new therapies

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  DOI: 10.1016/j.neuron.2022.12.012
  
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The human pre-replication complex is an open complex

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  DOI: 10.1016/j.cell.2022.12.008
  
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A central role for regulated protein stability in the control of TFE3 and MITF by nutrients

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Palmitoylation prevents sustained inflammation by limiting NLRP3 inflammasome activation through chaperone-mediated autophagy

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Two modes of Cue2-mediated mRNA cleavage with distinct substrate recognition initiate no-go decay

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  DOI: 10.1093/nar/gkac1172
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkac1172/6965460

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