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832 Matching Annotations

Nov 2020
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

TSPAN1: A Novel Protein Involved in Head and Neck Squamous Cell Carcinoma Chemoresistance

1
1. scibot 11 Nov 2020
  
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  pERK1/2
  
  DOI: 10.3390/cancers12113269
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
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  Curator comments: p44/42 MAP kinase (phosphorylated Erk1/2) antibody Cell Signaling Technology Cat# 9101
  
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pubmed.ncbi.nlm.nih.gov/33167355/
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A Broad Response to Intracellular Long-Chain Polyphosphate in Human Cells

1
1. scibot 05 Nov 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2020.108318
  
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sciencedirect.com/science/article/pii/S2211124720313073
Oct 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enhanced FGFR3 activity in postmitotic principal neurons during brain development results in cortical dysplasia and axonal tract abnormality

1
1. scibot 31 Oct 2020
  
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  RRID:AB_331646
  
  DOI: 10.1038/s41598-020-75537-0
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7595096/
elifesciences.org elifesciences.org

Optical control of ERK and AKT signaling promotes axon regeneration and functional recovery of PNS and CNS in Drosophila

1
1. scibot 24 Oct 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.57395
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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elifesciences.org/articles/57395
www.jneurosci.org www.jneurosci.org

Phosphorylation of eIF2α promotes Schwann cell differentiation and myelination in CMT1B mice with activated UPR

1
1. scibot 22 Oct 2020
  
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  RRID:AB_331646
  
  DOI: 10.1523/JNEUROSCI.0957-20.2020
  
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jneurosci.org/content/40/42/8174
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LRIG1-Mediated Inhibition of EGF Receptor Signaling Regulates Neural Precursor Cell Proliferation in the Neocortex

1
1. scibot 21 Oct 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2020.108257
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S2211124720312468
link.springer.com link.springer.com

Repurposing mesalazine against cardiac fibrosis in vitro

1
1. scibot 20 Oct 2020
  
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  Phospho-ERK 1/2 (p42/44)
  
  DOI: 10.1007/s00210-020-01998-9
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331646
  
  Curator comments: p44/42 MAP kinase (phosphorylated Erk1/2) antibody Cell Signaling Technology Cat# 9101
  
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link.springer.com/article/10.1007/s00210-020-01998-9/tables/1
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Activation of EphrinB2 Signaling Promotes Adaptive Venous Remodeling in Murine Arteriovenous Fistulae

1
1. scibot 10 Oct 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.jss.2020.08.071
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S002248042030634X
Sep 2020
onlinelibrary.wiley.com onlinelibrary.wiley.com

Sleep deprivation regulates availability of PrPC and Aβ peptides which can impair interaction between PrPC and laminin and neuronal plasticity

1
1. scibot 26 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1111/jnc.14960
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRID:AB_331646 RRIDCUR:Validated
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onlinelibrary.wiley.com/doi/10.1111/jnc.14960
bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com

BPS Publications

1
1. scibot 26 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1111/bph.15155
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15155
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Angiotensin II-upregulated MAP kinase phosphatase-3 modulates FOXO1 and p21 in adrenocortical H295R cells

1
1. scibot 25 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.heliyon.2020.e03519
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_331646
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S2405844020303649
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics

2
1. scibot 23 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.57410
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @evieth
  
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  RRID:AB_331646 RRIDCUR:Validated
2. scibot 03 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.57410
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_331646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7289600/
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Oncogenic Signaling Alters Cell Shape and Mechanics to Facilitate Cell Division under Confinement

1
1. scibot 23 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.devcel.2020.01.004
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @ethanbadger
  
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  RRID:AB_331646 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1534580720300058
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Neurofibromin Is an Estrogen Receptor-α Transcriptional Co-repressor in Breast Cancer

1
1. scibot 23 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.ccell.2020.02.003
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRID:AB_331646 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1535610820300921
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

The peroxisome counteracts oxidative stresses by suppressing catalase import via Pex14 phosphorylation

1
1. scibot 23 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.55896
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @evieth
  
  SciCrunch record: RRID:AB_331646
  
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  RRID:AB_331646 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC7498260/
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

HSP90 Inhibitor, 17-DMAG, Alone and in Combination with Lapatinib Attenuates Acquired Lapatinib-Resistance in ER-positive, HER2-Overexpressing Breast Cancer Cell Line

1
1. scibot 22 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.3390/cancers12092630
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:AB_331646
  
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  RRIDCUR:Validated RRID:AB_331646
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pubmed.ncbi.nlm.nih.gov/32942617/
elifesciences.org elifesciences.org

Existence and functions of a kisspeptin neuropeptide signaling system in a non-chordate deuterostome species

1
1. scibot 17 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.53370
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  SciCrunch record: RRID:AB_331646
  
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  RRID:AB_331646 RRIDCUR:Validated
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elifesciences.org/articles/53370
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Metabolic Fingerprinting Links Oncogenic PIK3CA with Enhanced Arachidonic Acid-Derived Eicosanoids

1
1. scibot 17 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.cell.2020.05.053
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:AB_331646
  
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  RRID:AB_331646 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0092867420306863
elifesciences.org elifesciences.org

Analysis of pulsed cisplatin signalling dynamics identifies effectors of resistance in lung adenocarcinoma

1
1. scibot 17 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.53367
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRID:AB_331646 RRIDCUR:Validated
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elifesciences.org/articles/53367
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mTORC1 Signaling Controls TLR2-Mediated T-Cell Activation by Inducing TIRAP Expression

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2020.107911
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S2211124720308925
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SpiCee: A Genetic Tool for Subcellular and Cell-Specific Calcium Manipulation

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2020.107934
  
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sciencedirect.com/science/article/pii/S2211124720309153
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Interleukin-33 Signaling Controls the Development of Iron-Recycling Macrophages

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.immuni.2020.03.006
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @ethanbadger
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S1074761320301199
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Caspase-6 Is a Key Regulator of Innate Immunity, Inflammasome Activation, and Host Defense

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.cell.2020.03.040
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S0092867420303330
onlinelibrary.wiley.com onlinelibrary.wiley.com

Activation of astrocytic sigma‐1 receptor exerts antidepressant‐like effect via facilitating CD38‐driven mitochondria transfer

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1002/glia.23850
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_331646
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onlinelibrary.wiley.com/doi/10.1002/glia.23850
academic.oup.com academic.oup.com

Inhibitory Interplay of SULT2B1b Sulfotransferase with AKR1C3 Aldo-keto Reductase in Prostate Cancer

1
1. scibot 16 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1210/endocr/bqz042
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @Naa003
  
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  RRIDCUR:Validated RRID:AB_331646
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academic.oup.com/endo/article/161/2/bqz042/5693375
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Thioredoxin-1 distinctly promotes NF-κB target DNA binding and NLRP3 inflammasome activation independently of Txnip

1
1. scibot 15 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.7554/eLife.53627
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
  Curator: @evieth
  
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  RRIDCUR:Validated RRID:AB_331646
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ncbi.nlm.nih.gov/pmc/articles/PMC7062472/
www.nature.com www.nature.com

Organotypic culture assays for murine and human primary and metastatic-site tumors

1
1. scibot 15 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1038/s41596-020-0335-3
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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nature.com/articles/s41596-020-0335-3
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FOXD3 Regulates VISTA Expression in Melanoma

1
1. scibot 14 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2019.12.036
  
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sciencedirect.com/science/article/pii/S2211124719316936
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Hotspots of Aberrant Enhancer Activity in Fibrolamellar Carcinoma Reveal Candidate Oncogenic Pathways and Therapeutic Vulnerabilities

1
1. scibot 14 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.celrep.2020.03.073
  
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sciencedirect.com/science/article/pii/S2211124720303995
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enhancement of Drug Seeking Following Drug Taking in a Sexual Context Requires Anterior Cingulate Cortex Activity in Male Rats

1
1. scibot 14 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.3389/fnbeh.2020.00087
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7330085/
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Exome Sequencing Identifies Genes and Gene Sets Contributing to Severe Childhood Obesity, Linking PHIP Variants to Repressed POMC Transcription

1
1. scibot 11 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.cmet.2020.05.007
  
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sciencedirect.com/science/article/pii/S1550413120302461
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Effects of acute aerobic, resistance and combined exercises on 24-h glucose variability and skeletal muscle signalling responses in type 1 diabetics

1
1. scibot 11 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1007/s00421-020-04491-6
  
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link.springer.com/article/10.1007/s00421-020-04491-6
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Developmental and Tumor Angiogenesis Requires the Mitochondria-Shaping Protein Opa1

1
1. scibot 10 Sep 2020
  
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  RRID:AB_331646
  
  DOI: 10.1016/j.cmet.2020.04.007
  
  Resource: (Cell Signaling Technology Cat# 9101, RRID:AB_331646)
  
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  RRIDCUR:Validated RRID:AB_331646
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sciencedirect.com/science/article/pii/S1550413120301893
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In vitro impact of FSH glycosylation variants on FSH receptor-stimulated signal transduction and functional selectivity

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Mutant ACVR1 Arrests Glial Cell Differentiation to Drive Tumorigenesis in Pediatric Gliomas

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DPP-4 inhibition with anagliptin reduces lipotoxicity-induced insulin resistance and steatohepatitis in male mice

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Symmetric Arginine Dimethylation Is Selectively Required for mRNA Splicing and the Initiation of Type I and Type III Interferon Signaling

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Three-dimensional growth of breast cancer cells potentiates the anti-tumor effects of unacylated ghrelin and AZP-531

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H1N1 Influenza Virus Cross-Activates Gli1 to Disrupt the Intercellular Junctions of Alveolar Epithelial Cells

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Hyperactivation of TORC1 Drives Resistance to the Pan-HER Tyrosine Kinase Inhibitor Neratinib in HER2-Mutant Cancers

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JNK signaling regulates oviposition in the malaria vector Anopheles gambiae

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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

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PTPN2 Deficiency Enhances Programmed T Cell Expansion and Survival Capacity of Activated T Cells

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Long-Term Memory Engram Cells Are Established by c-Fos/CREB Transcriptional Cycling

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PD-1 Inhibitory Receptor Downregulates Asparaginyl Endopeptidase and Maintains Foxp3 Transcription Factor Stability in Induced Regulatory T Cells

1
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  Phospho-ERK
  
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Pyruvate Kinase M2 Promotes the Activation of Dendritic Cells by Enhancing IL-12p35 Expression

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Novel role for CRK adaptor proteins as essential components of SRC/FAK signaling for epithelial‐mesenchymal transition and colorectal cancer aggressiveness

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  Thr202/Tyr204 phospho‐ERK1/2
  
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The YEATS Domain Histone Crotonylation Readers Control Virulence-Related Biology of a Major Human Pathogen

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  Phospho-p44/42 MAPK (Erk1/2) (Thr202/Tyr204)
  
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Dynamic ROS Control by TIGAR Regulates the Initiation and Progression of Pancreatic Cancer

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Cyclopentenone Prostaglandins and Structurally Related Oxidized Lipid Species Instigate and Share Distinct Pro- and Anti-inflammatory Pathways

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Adaptive RSK‐EphA2‐GPRC5A signaling switch triggers chemotherapy resistance in ovarian cancer

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  ERK1/2_pT202/Y204
  
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Prevention and Reversion of Pancreatic Tumorigenesis through a Differentiation-Based Mechanism

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Genomic and Transcriptomic Determinants of Therapy Resistance and Immune Landscape Evolution during Anti-EGFR Treatment in Colorectal Cancer

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1,25-dihydroxyvitamin D maintains brush border membrane NaPi2a and attenuates phosphaturia in Hyp mice

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Dual and Opposing Functions of the Central Amygdala in the Modulation of Pain

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Enhanced mGlu5 Signaling in Excitatory Neurons Promotes Rapid Antidepressant Effects via AMPA Receptor Activation

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Mucosal Profiling of Pediatric-Onset Colitis and IBD Reveals Common Pathogenics and Therapeutic Pathways

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Phosphorylated Rasal2 facilitates breast cancer progression

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Defective AMH signaling disrupts GnRH neuron development and function and contributes to hypogonadotropic hypogonadism

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An acquired scaffolding function of the DNAJ-PKAc fusion contributes to oncogenic signaling in fibrolamellar carcinoma

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Sphingosine 1‐phosphate but not Fingolimod protects neurons against excitotoxic cell death by inducing neurotrophic gene expression in astrocytes

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Removal of the potassium chloride co-transporter from the somatodendritic membrane of axotomized motoneurons is independent of BDNF/TrkB signaling but is controlled by neuromuscular innervation

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Conformational Sensors and Domain Swapping Reveal Structural and Functional Differences between β-Arrestin Isoforms

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A Receptor of the Immunoglobulin Superfamily Regulates Adaptive Thermogenesis

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Molecularly Distinct Clathrin-Coated Pits Differentially Impact EGFR Fate and Signaling

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Peptide/Receptor Co-evolution Explains the Lipolytic Function of the Neuropeptide TLQP-21

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The Receptor Kinases BAK1/SERK4 Regulate Ca2+ Channel-Mediated Cellular Homeostasis for Cell Death Containment

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Combination of Hypoglycemia and Metformin Impairs Tumor Metabolic Plasticity and Growth by Modulating the PP2A-GSK3β-MCL-1 Axis

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Effect of early-stage autophagy inhibition in BRAF V600E autophagy-dependent brain tumor cells

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The calcium‐activated protease calpain regulates netrin‐1 receptor deleted in colorectal cancer (DCC)‐induced axon outgrowth in cortical neurons

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LC3C-Mediated Autophagy Selectively Regulates the Met RTK and HGF-Stimulated Migration and Invasion

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Contrasting patterns of ERK activation in the tail of the striatum in response to aversive and rewarding signals

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A multimolecular signaling complex including PrPC and LRP1 is strictly dependent on lipid rafts and is essential for the function of tissue Plasminogen Activator

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EGFR Signaling Termination via Numb Trafficking in Ependymal Progenitors Controls Postnatal Neurogenic Niche Differentiation

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CRH Promotes the Neurogenic Activity of Neural Stem Cells in the Adult Hippocampus

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Cross-Microbial Protection via Priming a Conserved Immune Co-Receptor through Juxtamembrane Phosphorylation in Plants

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ERK1/2 Phosphorylation of FHOD Connects Signaling and Nuclear Positioning Alternations in Cardiac Laminopathy

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Receptor-specific interactome as a hub for rapid cue-induced selective translation in axons

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Histamine H1 and H3 receptor activation increases the expression of Glucose Transporter 1 (GLUT-1) in rat cerebro-cortical astrocytes in primary culture

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A Spontaneous Aggressive ERα+ Mammary Tumor Model Is Driven by Kras Activation

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The regulation of oocyte maturation and ovulation in the closest sister group of vertebrates

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Lipid Deprivation Induces a Stable, Naive-to-Primed Intermediate State of Pluripotency in Human PSCs

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Bilirubin Links Heme Metabolism to Neuroprotection by Scavenging Superoxide

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TAZ Is a Negative Regulator of PPARγ Activity in Adipocytes and TAZ Deletion Improves Insulin Sensitivity and Glucose Tolerance

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Dualism of FGF and TGF-β Signaling in Heterogeneous Cancer-Associated Fibroblast Activation with ETV1 as a Critical Determinant

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Photocrosslinking Activity-Based Probes for Ubiquitin RING E3 Ligases

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Genetic Heterogeneity of BRAF Fusion Kinases in Melanoma Affects Drug Responses

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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

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Glutamate Signaling in Hepatic Stellate Cells Drives Alcoholic Steatosis

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Drp1 Promotes KRas-Driven Metabolic Changes to Drive Pancreatic Tumor Growth

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Shank Proteins Couple the Endocytic Zone to the Postsynaptic Density to Control Trafficking and Signaling of Metabotropic Glutamate Receptor 5

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Auto-regulation of Secretory Flux by Sensing and Responding to the Folded Cargo Protein Load in the Endoplasmic Reticulum

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Reciprocal Effects of Fibroblast Growth Factor Receptor Signaling on Dengue Virus Replication and Virion Production

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Regulation of the Elongation Phase of Protein Synthesis Enhances Translation Accuracy and Modulates Lifespan

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Conditional BDNF Delivery from Astrocytes Rescues Memory Deficits, Spine Density, and Synaptic Properties in the 5xFAD Mouse Model of Alzheimer Disease

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Amino alkynylisoquinoline and alkynylnaphthyridine compounds potently inhibit acute myeloid leukemia proliferation in mice

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Tracing MYC Expression for Small Molecule Discovery

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Inhibition of LTA4H by bestatin in human and mouse colorectal cancer

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Obesity Drives STAT-1-Dependent NASH and STAT-3-Dependent HCC

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Modulation of DNA Repair Systems in Blind Cavefish during Evolution in Constant Darkness

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Pharmacological Induction of RAS-GTP Confers RAF Inhibitor Sensitivity in KRAS Mutant Tumors

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miR‐4725‐3p targeting Stim1 signaling is involved in xanthohumol inhibition of glioma cell invasion

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Estrogen Regulation of GRK2 Inactivates Kappa Opioid Receptor Signaling Mediating Analgesia, But Not Aversion

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Divergent Matrix-Remodeling Strategies Distinguish Developmental from Neoplastic Mammary Epithelial Cell Invasion Programs

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Vascular and Neurogenic Rejuvenation in Aging Mice by Modulation of ASM

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Muscarinic receptor antagonists activate ERK-CREB signaling to augment neurite outgrowth of adult sensory neurons

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Translational and HIF-1α-Dependent Metabolic Reprogramming Underpin Metabolic Plasticity and Responses to Kinase Inhibitors and Biguanides

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SYK-CARD9 Signaling Axis Promotes Gut Fungi-Mediated Inflammasome Activation to Restrict Colitis and Colon Cancer

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Swedish Nerve Growth Factor Mutation (NGFR100W) Defines a Role for TrkA and p75NTR in Nociception

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Overcoming Resistance to Dual Innate Immune and MEK Inhibition Downstream of KRAS

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Increased Lactate Secretion by Cancer Cells Sustains Non-cell-autonomous Adaptive Resistance to MET and EGFR Targeted Therapies

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TBK1 Suppresses RIPK1-Driven Apoptosis and Inflammation during Development and in Aging

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Generation of Hepatic Stellate Cells from Human Pluripotent Stem Cells Enables In Vitro Modeling of Liver Fibrosis

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Extracellular Matrix Components HAPLN1, Lumican, and Collagen I Cause Hyaluronic Acid-Dependent Folding of the Developing Human Neocortex

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Human iPSC-Derived Natural Killer Cells Engineered with Chimeric Antigen Receptors Enhance Anti-tumor Activity

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Loss of PRMT5 Promotes PDGFRα Degradation during Oligodendrocyte Differentiation and Myelination

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IDH2 Deficiency in Microglia Decreases the Pro-inflammatory Response <Emphasis Type="Italic">via</Emphasis> the ERK and NF-κB Pathways

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Mitofusin 2 Regulates Axonal Transport of Calpastatin to Prevent Neuromuscular Synaptic Elimination in Skeletal Muscles

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Gain-of-Function Mutation of Card14 Leads to Spontaneous Psoriasis-like Skin Inflammation through Enhanced Keratinocyte Response to IL-17A

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Intestinal Epithelial Cell Autophagy Is Required to Protect against TNF-Induced Apoptosis during Chronic Colitis in Mice

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Loss of STI1‐mediated neuronal survival and differentiation in disease‐associated mutations of prion protein

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MAP Kinase Cascades Regulate the Cold Response by Modulating ICE1 Protein Stability

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Acetyl-CoA Carboxylase 1-Dependent Protein Acetylation Controls Breast Cancer Metastasis and Recurrence

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A Tyrosine Phosphorylation Cycle Regulates Fungal Activation of a Plant Receptor Ser/Thr Kinase

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R-Ras1 and R-Ras2 Are Essential for Oligodendrocyte Differentiation and Survival for Correct Myelination in the Central Nervous System

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Interaction of CacyBP/SIP with NPM1 and its influence on NPM1 localization and function in oxidative stress

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An ERK-Dependent Feedback Mechanism Prevents Hematopoietic Stem Cell Exhaustion

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The Dietary Supplement Chondroitin-4-Sulfate Exhibits Oncogene-Specific Pro-tumor Effects on BRAF V600E Melanoma Cells

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Pan-RAF and MEK vertical inhibition enhances therapeutic response in non-V600 BRAF mutant cells

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GDC-0879, a BRAFV600E Inhibitor, Protects Kidney Podocytes from Death

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Increased Circulating FGF23 Does Not Lead to Cardiac Hypertrophy in the Male Hyp Mouse Model of XLH

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The Receptor-like Cytoplasmic Kinase BIK1 Localizes to the Nucleus and Regulates Defense Hormone Expression during Plant Innate Immunity

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CD69 partially inhibits apoptosis and erythroid differentiation via CD24, and their knockdown increase imatinib sensitivity in BCR‐ABL‐positive cells

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EGFR-Phosphorylated Platelet Isoform of Phosphofructokinase 1 Promotes PI3K Activation

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Extracellular Lactate Dehydrogenase A Release From Damaged Neurons Drives Central Nervous System Angiogenesis

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c-RAF Ablation Induces Regression of Advanced Kras/Trp53 Mutant Lung Adenocarcinomas by a Mechanism Independent of MAPK Signaling

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Interleukin-10 Directly Inhibits CD8+ T Cell Function by Enhancing N-Glycan Branching to Decrease Antigen Sensitivity

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Arctic Aβ40 blocks the nicotine-induced neuroprotective effect of CHRNA7 by inhibiting the ERK1/2 pathway in human neuroblastoma cells

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An RNAi screen of Rho signalling networks identifies RhoH as a regulator of Rac1 in prostate cancer cell migration

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Microenvironment-Mediated Mechanisms of Resistance to HER2 Inhibitors Differ between HER2+ Breast Cancer Subtypes

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Catch-Up Growth in Zebrafish Embryo Requires Neural Crest Cells Sustained by Irs1 Signaling

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Oncogenic Role of THOR, a Conserved Cancer/Testis Long Non-coding RNA

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Origins and Specification of the Drosophila Wing

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OsMAPK3 Phosphorylates OsbHLH002/OsICE1 and Inhibits Its Ubiquitination to Activate OsTPP1 and Enhances Rice Chilling Tolerance

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The Neuroprotective Effect of Thalidomide against Ischemia through the Cereblon-mediated Repression of AMPK Activity

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β2 Adrenergic-Neurotrophin Feedforward Loop Promotes Pancreatic Cancer

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Hyperinnervation improves Xenopus laevis limb regeneration

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Natural Killer Cells Control Tumor Growth by Sensing a Growth Factor

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Long-Fiber Carbon Nanotubes Replicate Asbestos-Induced Mesothelioma with Disruption of the Tumor Suppressor Gene Cdkn2a (Ink4a/Arf)

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CK2 oppositely modulates L-DOPA induced dyskinesia via striatal projection neurons expressing D1- or D2-receptors

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Tuning of in vivo cognate B-T cell interactions by Intersectin 2 is required for effective anti-viral B cell immunity.

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FGF19, FGF21, and an FGFR1/β-Klotho-Activating Antibody Act on the Nervous System to Regulate Body Weight and Glycemia

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MST4 Phosphorylation of ATG4B Regulates Autophagic Activity, Tumorigenicity, and Radioresistance in Glioblastoma

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Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas

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Cannabinoid Receptor Type 1 Agonist ACEA Protects Neurons from Death and Attenuates Endoplasmic Reticulum Stress-Related Apoptotic Pathway Signaling

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A General Strategy for Discovery of Inhibitors and Activators of RING and U-box E3 Ligases with Ubiquitin Variants

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A chemical screen in zebrafish embryonic cells establishes that Akt activation is required for neural crest development

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Carbon Black Nanoparticles Inhibit Aromatase Expression and Estradiol Secretion in Human Granulosa Cells Through the ERK1/2 Pathway

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Protease activated receptor 2 controls myelin development, resiliency and repair

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A Ketogenic Diet Extends Longevity and Healthspan in Adult Mice

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Endogenous, Regulatory Cysteine Sulfenylation of ERK Kinases in Response to Proliferative Signals

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Heparan sulfate alterations in extracellular matrix structures and fibroblast growth factor‐2 signaling impairment in the aged neurogenic niche

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Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action

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GATA Factor-Regulated Samd14 Enhancer Confers Red Blood Cell Regeneration and Survival in Severe Anemia

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Purinergic receptor P2Y6 contributes to 1‐methyl‐4‐phenylpyridinium‐induced oxidative stress and cell death in neuronal SH‐SY5Y cells

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Intra‐prelimbic cortical inhibition of striatal‐enriched tyrosine phosphatase suppresses cocaine seeking in rats

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Neurodegenerative effects of azithromycin in differentiated PC12 cells - ScienceDirect

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Stimulus evoked ERK-dependent phosphorylation of activity-regulated cytoskeleton-associated protein (Arc) regulates its neuronal subcellular localization

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Crosstalk control and limits of physiological c-Jun N-terminal kinase activity for cell viability and neurite stability in differentiated PC12 cells - ScienceDirect

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Stabilization of the c-Myc Protein by CAMKIIγ Promotes T Cell Lymphoma

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EGFR Induces E2F1-Mediated Corticotroph Tumorigenesis

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The Sec14-like phosphatidylinositol transfer proteins Sec14l3/SEC14L2 act as GTPase proteins to mediate Wnt/Ca2+ signaling

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TREM2 Promotes Microglial Survival by Activating Wnt/β-Catenin Pathway

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