1,349 Matching Annotations
  1. Nov 2022
  2. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
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    NEIL3 contributes to the Fanconi anemia/BRCA pathway by promoting the downstream double-strand break repair step
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    sciencedirect.com/science/article/pii/S2211124722014656
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    Targeting the MITF/APAF-1 axis as salvage therapy for MAPK inhibitors in resistant melanoma
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    sciencedirect.com/science/article/pii/S2211124722014668
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    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
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    sciencedirect.com/science/article/pii/S2451945622003579
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    Metabolic regulation by p53 prevents R-loop-associated genomic instability
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    sciencedirect.com/science/article/pii/S2211124722014292
  7. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Deletion of Nox4 enhances remyelination following cuprizone-induced demyelination by increasing phagocytic capacity of microglia and macrophages in mice
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    onlinelibrary.wiley.com/doi/10.1002/glia.24292
  8. Oct 2022
  9. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Brain Endothelial Cells in Contrary to the Aortic Do Not Transport but Degrade Low-Density Lipoproteins via Both LDLR and ALK1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9564369/
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The proprotein convertase furin regulates the development of thymic epithelial cells to ensure central immune tolerance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9579486/
  11. journals.lww.com journals.lww.com
    Long noncoding RNA Pvt1 promotes the proliferation and... : Neural Regeneration Research
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    journals.lww.com/nrronline/Fulltext/2023/05000/Long_noncoding_RNA_Pvt1_promotes_the_proliferation.35.aspx
  12. elifesciences.org elifesciences.org
    GCN2 eIF2 kinase promotes prostate cancer by maintaining amino acid homeostasis
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    elifesciences.org/articles/81083
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    The rheumatoid arthritis drug auranofin lowers leptin levels and exerts antidiabetic effects in obese mice
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    sciencedirect.com/science/article/pii/S1550413122004090
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    Induction of the hepatic aryl hydrocarbon receptor by alcohol dysregulates autophagy and phospholipid metabolism via PPP2R2D
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    nature.com/articles/s41467-022-33749-0
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    Long-term potentiation reconstituted with an artificial TARP/PSD-95 complex
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    sciencedirect.com/science/article/pii/S221112472201333X
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    Competition for endothelial cell polarity drives vascular morphogenesis in the mouse retina
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    sciencedirect.com/science/article/pii/S1534580722006323
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    Validation of a non-oncogene encoded vulnerability to exportin 1 inhibition in pediatric renal tumors
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    sciencedirect.com/science/article/pii/S2666634022004032
  18. Sep 2022
  19. www.sciencedirect.com www.sciencedirect.com
    A genetically modified minipig model for Alzheimer’s disease with SORL1 haploinsufficiency
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    sciencedirect.com/science/article/pii/S2666379122002890
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC9437572/
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    S1-END-seq reveals DNA secondary structures in human cells
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    sciencedirect.com/science/article/pii/S1097276522007602
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    m1A and m6A modifications function cooperatively to facilitate rapid mRNA degradation
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    sciencedirect.com/science/article/pii/S221112472201141X
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    Convergent cerebrospinal fluid proteomes and metabolic ontologies in humans and animal models of Rett syndrome
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    sciencedirect.com/science/article/pii/S258900422201238X
  24. Aug 2022
  25. www.sciencedirect.com www.sciencedirect.com
    Huntingtin coordinates dendritic spine morphology and function through cofilin-mediated control of the actin cytoskeleton
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    sciencedirect.com/science/article/pii/S2211124722010798
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    Mfsd2b and Spns2 are essential for maintenance of blood vessels during development and in anaphylactic shock
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    sciencedirect.com/science/article/pii/S2211124722010257
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    Targeting HOTAIRM1 ameliorates glioblastoma by disrupting mitochondrial oxidative phosphorylation and serine metabolism
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    sciencedirect.com/science/article/pii/S2589004222010951
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15920
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    Expression pattern of NLRC5 in the postnatal mouse brain
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    sciencedirect.com/science/article/pii/S0065128122000988
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    DNA methyltransferase 3 alpha and TET methylcytosine dioxygenase 2 restrain mitochondrial DNA-mediated interferon signaling in macrophages
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    sciencedirect.com/science/article/pii/S1074761322002953
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    Cancer genes disfavoring T cell immunity identified via integrated systems approach
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    sciencedirect.com/science/article/pii/S2211124722009627
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    Regulation of alternative polyadenylation by the C2H2-zinc-finger protein Sp1
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    sciencedirect.com/science/article/pii/S1097276522006499
  33. Jul 2022
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Method for In Situ Reverse Genetic Analysis of Proteins Involved mtDNA Replication
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    ncbi.nlm.nih.gov/pmc/articles/PMC9316749/
  35. www.sciencedirect.com www.sciencedirect.com
    Skeletal progenitors preserve proliferation and self-renewal upon inhibition of mitochondrial respiration by rerouting the TCA cycle
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    sciencedirect.com/science/article/pii/S221112472200907X
  36. www.nature.com www.nature.com
    LRRK2 kinase activity regulates GCase level and enzymatic activity differently depending on cell type in Parkinson’s disease
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    nature.com/articles/s41531-022-00354-3
  37. academic.oup.com academic.oup.com
    IGSF1 deficiency leads to reduced TSH production independent of alterations in thyroid hormone action in male mice
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    academic.oup.com/endo/article/163/8/bqac092/6609251
  38. www.sciencedirect.com www.sciencedirect.com
    Poziotinib for EGFR exon 20-mutant NSCLC: Clinical efficacy, resistance mechanisms, and impact of insertion location on drug sensitivity
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    sciencedirect.com/science/article/pii/S1535610822002707
  39. www.sciencedirect.com www.sciencedirect.com
    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
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    sciencedirect.com/science/article/pii/S1534580722004488
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Upregulation of FOXO1 contributes to lipopolysaccharide-induced pulmonary endothelial injury by induction of autophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC9263762/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BACE-1 inhibition facilitates the transition from homeostatic microglia to DAM-1
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    ncbi.nlm.nih.gov/pmc/articles/PMC9205595/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    ncbi.nlm.nih.gov/pmc/articles/PMC9056178/
  43. www.sciencedirect.com www.sciencedirect.com
    Diverging regulation of Bach2 protein and RNA expression determine cell fate in early B cell response
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    sciencedirect.com/science/article/pii/S2211124722008294
  44. Jun 2022
  45. www.sciencedirect.com www.sciencedirect.com
    BAFFR activates PI3K/AKT signaling in human naive but not in switched memory B cells through direct interactions with B cell antigen receptors
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    sciencedirect.com/science/article/pii/S2211124722008087
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    Clioquinol as an inhibitor of JmjC-histone demethylase exhibits common and unique histone methylome and transcriptome between clioquinol and hypoxia
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    sciencedirect.com/science/article/pii/S258900422200788X
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mechanoreceptor Piezo1 Is Downregulated in Multiple Sclerosis Brain and Is Involved in the Maturation and Migration of Oligodendrocytes in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC9204635/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Senescence-induced endothelial phenotypes underpin immune-mediated senescence surveillance
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    ncbi.nlm.nih.gov/pmc/articles/PMC9186388/
  49. www.sciencedirect.com www.sciencedirect.com
    Riboregulation of Enolase 1 activity controls glycolysis and embryonic stem cell differentiation
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    sciencedirect.com/science/article/pii/S1097276522004865
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocarboxylate transporter 1 deficiency impacts CD8+ T lymphocytes proliferation and recruitment to adipose tissue during obesity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9189020/
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    A TET1-PSPC1-Neat1 molecular axis modulates PRC2 functions in controlling stem cell bivalency
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    sciencedirect.com/science/article/pii/S2211124722007100
  52. www.science.org www.science.org
    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    science.org/doi/full/10.1126/sciadv.abl5032
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective endocytosis of Ca2+-permeable AMPARs by the Alzheimer’s disease risk factor CALM bidirectionally controls synaptic plasticity
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    ncbi.nlm.nih.gov/pmc/articles/PMC9132451/
  54. May 2022
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sortilin Modulates Schwann Cell Signaling and Remak Bundle Regeneration Following Nerve Injury
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    ncbi.nlm.nih.gov/pmc/articles/PMC9130554/
  56. www.sciencedirect.com www.sciencedirect.com
    UPF1 promotes rapid degradation of m6A-containing RNAs
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    sciencedirect.com/science/article/pii/S2211124722006349
  57. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
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    sciencedirect.com/science/article/pii/S2211124722006295
  58. www.sciencedirect.com www.sciencedirect.com
    XIST loss impairs mammary stem cell differentiation and increases tumorigenicity through Mediator hyperactivation
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    sciencedirect.com/science/article/pii/S0092867422005323
  59. aacrjournals.org aacrjournals.org
    Increased microtubule growth triggered by microvesicle-mediated paracrine signaling is required for melanoma cancer cell invasion
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    aacrjournals.org/cancerrescommun/article/2/5/366/698979/Increased-Microtubule-Growth-Triggered-by
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intrinsically disordered regions couple the ligand binding and kinase activation of Trk neurotrophin receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC9117555/
  61. www.researchsquare.com www.researchsquare.com
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    researchsquare.com/article/rs-7216019/'https://www.researchsquare.com/article/rs-7216019/v1
  62. www.sciencedirect.com www.sciencedirect.com
    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
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    sciencedirect.com/science/article/pii/S0092867422005268
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    CDX2-induced intestinal metaplasia in human gastric organoids derived from induced pluripotent stem cells
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    sciencedirect.com/science/article/pii/S2589004222005855
  64. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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    sciencedirect.com/science/article/pii/S1097276522003264
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dysfunction of Inflammatory Pathways and Their Relationship With Psychological Factors in Adult Female Patients With Eating Disorders
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    ncbi.nlm.nih.gov/pmc/articles/PMC9062031/
  66. www.nature.com www.nature.com
    Convergent somatic mutations in metabolism genes in chronic liver disease
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    nature.com/articles/s41586-021-03974-6
  67. www.sciencedirect.com www.sciencedirect.com
    Loss of PRMT7 reprograms glycine metabolism to selectively eradicate leukemia stem cells in CML
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    sciencedirect.com/science/article/pii/S1550413122001310
  68. www.cell.com www.cell.com
    Systematic discovery of mutation-directed neo-protein-protein interactions in cancer
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    cell.com/cell/fulltext/S0092-8674(22)00461-5
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  70. Apr 2022
  71. www.sciencedirect.com www.sciencedirect.com
    PIIS2589004222005594-html.html
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    sciencedirect.com/science/article/pii/S2589004222005594
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    Adeno-associated-virus-mediated gene delivery to ovaries restores fertility in congenital infertile mice
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    sciencedirect.com/science/article/pii/S2666379122001239
  73. link.springer.com link.springer.com
    Energetic metabolic reprogramming in Jurkat DFF40-deficient cancer cells
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    link.springer.com/article/10.1007/s11010-022-04433-0
  74. aacrjournals.org aacrjournals.org
    Rational Combination of CRM1 Inhibitor Selinexor and Olaparib Shows Synergy in Ovarian Cancer Cell Lines and Mouse Models
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    aacrjournals.org/mct/article/20/12/2352/675163/Rational-Combination-of-CRM1-Inhibitor-Selinexor
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    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
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    sciencedirect.com/science/article/pii/S1097276522002696
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    DNA replication is highly resilient and persistent under the challenge of mild replication stress
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    sciencedirect.com/science/article/pii/S2211124722004594
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    Glutamatergic synapses from the insular cortex to the basolateral amygdala encode observational pain
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    sciencedirect.com/science/article/pii/S0896627322002665
  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T-lymphopoiesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC9010627/
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    Identification and evaluation of a lipid-lowering small compound in preclinical models and in a Phase I trial
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    sciencedirect.com/science/article/pii/S1550413122000948
  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effector membrane translocation biosensors reveal G protein and βarrestin coupling profiles of 100 therapeutically relevant GPCRs
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    ncbi.nlm.nih.gov/pmc/articles/PMC9005190/
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    Rapid establishment of human colonic organoid knockout lines
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    sciencedirect.com/science/article/pii/S2666166722001885
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    Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes
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    Brown adipose tissue involution associated with progressive restriction in progenitor competence
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    sciencedirect.com/science/article/pii/S2211124722003199
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    Epithelial STAT6 O-GlcNAcylation drives a concerted anti-helminth alarmin response dependent on tuft cell hyperplasia and Gasdermin C
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    sciencedirect.com/science/article/pii/S1074761322001327
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    MIRO2 regulates prostate cancer cell growth via GCN1-dependent stress signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC8983529/
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    Carbamazepine promotes surface expression of mutant Kir6.2-A28V ATP-sensitive potassium channels by modulating Golgi retention and autophagy
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    sciencedirect.com/science/article/pii/S0021925822003441
  87. academic.oup.com academic.oup.com
    Inflammasome activation and pyroptosis via a lipid-regulated SIRT1-p53-ASC axis in macrophages from male mice and humans
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    academic.oup.com/endo/article/163/4/bqac014/6523230
  88. aacrjournals.org aacrjournals.org
    δ-Tocotrienol is the most potent vitamin E form in inhibiting prostate cancer cell growth and inhibits prostate carcinogenesis in Ptenp-/- mice
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    aacrjournals.org/cancerpreventionresearch/article/15/4/233/682296/Tocotrienol-is-the-Most-Potent-Vitamin-E-Form-in
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dual signaling via interferon and DNA damage response elicits entrapment by giant PML nuclear bodies
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    ncbi.nlm.nih.gov/pmc/articles/PMC8975554/
  90. Mar 2022
  91. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.14558
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    Acute inflammation down-regulates alpha-synuclein expression in enteric neurons
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14656
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    sciencedirect.com/science/article/pii/S2211124722003278
  94. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Quantitative interaction proteomics reveals differences in the interactomes of amyloid precursor protein isoforms
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    onlinelibrary.wiley.com/doi/10.1111/jnc.14666
  95. www.embopress.org www.embopress.org
    Endosomal phosphatidylinositol 3-phosphate controls synaptic vesicle cycling and neurotransmission
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    embopress.org/doi/abs/10.15252/embj.2021109352
  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Distinct and diverse chromatin proteomes of ageing mouse organs reveal protein signatures that correlate with physiological functions
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    ncbi.nlm.nih.gov/pmc/articles/PMC8933006/
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Population genomics reveals that natural variation in PRDM16 contributes to cold tolerance in domestic cattle
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