924 Matching Annotations
  1. Feb 2022
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    Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers
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    sciencedirect.com/science/article/pii/S221112472200016X
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    SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage
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    sciencedirect.com/science/article/pii/S1097276522000016
  4. Jan 2022
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8752093/
  6. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Feedback-regulated transcriptional repression of FBXO31 by c-Myc triggers ovarian cancer tumorigenesis
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33854
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC8666707/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8254761/
  9. Dec 2021
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC11166264/
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    USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1
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    sciencedirect.com/science/article/pii/S2211124721016740
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    MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma
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    sciencedirect.com/science/article/pii/S147655862100107X
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    Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer
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    sciencedirect.com/science/article/pii/S2352396421005442
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    MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase
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    sciencedirect.com/science/article/pii/S1097276521009953
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    Glutamine deprivation triggers NAGK-dependent hexosamine salvage
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    ncbi.nlm.nih.gov/pmc/articles/PMC8631944/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8178204/
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    Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer
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    sciencedirect.com/science/article/pii/S2211124721015552
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    Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I
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    sciencedirect.com/science/article/pii/S2451945621004797
  19. Nov 2021
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    Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition
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    sciencedirect.com/science/article/pii/S2451945621004827
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    Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis
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    sciencedirect.com/science/article/pii/S2211124721015424
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    A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer
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    sciencedirect.com/science/article/pii/S004520682100883X
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.16261
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    Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation
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    sciencedirect.com/science/article/pii/S1097276521009539
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    Short-chain fatty acids activate acetyltransferase p300
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    ncbi.nlm.nih.gov/pmc/articles/PMC8585482/
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    Toward comprehensive imaging of oncolytic viroimmunotherapy
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    sciencedirect.com/science/article/pii/S2372770521000905
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    Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity
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    sciencedirect.com/science/article/pii/S258900422101292X
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    sciencedirect.com/science/article/pii/S1097276521009072
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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    sciencedirect.com/science/article/pii/S2211124721014686
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
  31. Oct 2021
  32. www.sciencedirect.com www.sciencedirect.com
    Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors
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    sciencedirect.com/science/article/pii/S2451945621004414
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    Reprogramming CBX8-PRC1 function with a positive allosteric modulator
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    sciencedirect.com/science/article/pii/S2451945621004372
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    Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation
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    sciencedirect.com/science/article/pii/S2211124721013693
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    XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer
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    nature.com/articles/s41392-021-00761-7
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    USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork
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    sciencedirect.com/science/article/pii/S2211124721012833
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    Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis
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    sciencedirect.com/science/article/pii/S2211124721012791
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    Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments
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    sciencedirect.com/science/article/pii/S0160412021005468
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    Proteome-wide mapping of short-lived proteins in human cells
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    sciencedirect.com/science/article/pii/S1097276521007498
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines
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    ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
  41. academic.oup.com academic.oup.com
    Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions
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    academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
  42. Sep 2021
  43. www.mdpi.com www.mdpi.com
    Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates
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    mdpi.com/1424-8247/14/10/950
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    Oncogene-dependent sloppiness in mRNA translation
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    sciencedirect.com/science/article/pii/S109727652100736X
  45. academic.oup.com academic.oup.com
    CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
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    Alternative microexon splicing by RBFOX2 and PTBP1 is associated with metastasis in colorectal cancer
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    onlinelibrary.wiley.com/doi/10.1002/ijc.33758
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    ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction
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    sciencedirect.com/science/article/pii/S2211124721011530
  48. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells
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    onlinelibrary.wiley.com/doi/10.1002/cam4.4212
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    Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer
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    sciencedirect.com/science/article/pii/S002432052100936X
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    Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor
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    sciencedirect.com/science/article/pii/S1535610821004499
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    REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps
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    sciencedirect.com/science/article/pii/S1097276521006833
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    SPT5 stabilization of promoter-proximal RNA polymerase II
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    sciencedirect.com/science/article/pii/S1097276521006468
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    High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment
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    sciencedirect.com/science/article/pii/S2211124721010755
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    iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation
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    sciencedirect.com/science/article/pii/S2211124721010858
  55. Aug 2021
  56. link.springer.com link.springer.com
    YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models
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    link.springer.com/article/10.1007/s13402-021-00630-z
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    Entosis is induced by UV radiation.
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    sciencedirect.com/science/article/pii/S2589004221008701
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC8355564/
  59. www.biorxiv.org www.biorxiv.org
    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism
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    biorxiv.org/content/10.1101/141952v4
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    ncbi.nlm.nih.gov/pmc/articles/PMC5836092/
  61. elifesciences.org elifesciences.org
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    elifesciences.org/articles/26876
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    elifesciences.org/articles/22900
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27653
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    onlinelibrary.wiley.com/doi/full/10.1002/jcp.27359
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    onlinelibrary.wiley.com/doi/full/10.1002/jcb.27532
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    KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses
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    sciencedirect.com/science/article/pii/S1931312818301483
  68. www.nature.com www.nature.com
    BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination
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    nature.com/articles/s41586-021-03776-w
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization
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    ncbi.nlm.nih.gov/pmc/articles/PMC8331188/
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    Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy
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    sciencedirect.com/science/article/pii/S1534580721005621
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    Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.
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    europepmc.org/articles/PMC5655136/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53
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    ncbi.nlm.nih.gov/pmc/articles/PMC8321552/
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    Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy
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    link.springer.com/article/10.1186/s40170-019-0202-2
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12600
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    An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis
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    sciencedirect.com/science/article/pii/S1097276519307944
  81. Jul 2021
  82. www.sciencedirect.com www.sciencedirect.com
    Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination
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    sciencedirect.com/science/article/pii/S1097276519309244
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    Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas
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    sciencedirect.com/science/article/pii/S2211124719314056
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    Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis
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    sciencedirect.com/science/article/pii/S1097276519307932
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    NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor
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    sciencedirect.com/science/article/pii/S2211124719312914
  86. elifesciences.org elifesciences.org
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    elifesciences.org/articles/31326
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    TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress
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    sciencedirect.com/science/article/pii/S1097276519302588
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    Widespread and Functional RNA Circularization in Localized Prostate Cancer
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    sciencedirect.com/science/article/pii/S0092867419300583
  89. www.oncotarget.com www.oncotarget.com
    Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone
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    oncotarget.com/index.php
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    Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers
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    sciencedirect.com/science/article/pii/S2211124719311520
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    Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization
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    sciencedirect.com/science/article/pii/S1535610819303745
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    The Cancer SENESCopedia: A delineation of cancer cell senescence
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    Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization
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    sciencedirect.com/science/article/pii/S2352396419307522
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    Oncogenic MYC amplifies mitotic perturbations
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    royalsocietypublishing.org/doi/full/10.1098/rsob.190136
  95. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells
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    onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32608
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    Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction
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    Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy
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    elifesciences.org/articles/27301
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    Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair
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