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Nov 2022
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Pan-cancer analysis of tissue and single-cell HIF-pathway activation using a conserved gene signature

1
1. scibot 16 Nov 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2022.111652
  
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sciencedirect.com/science/article/pii/S2211124722015236
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A nascent peptide code for translational control of mRNA stability in human cells

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1. scibot 15 Nov 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41467-022-34664-0
  
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nature.com/articles/s41467-022-34664-0
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Enhanced DNA repair through droplet formation and p53 oscillations

1
1. scibot 11 Nov 2022
  
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  DOI: 10.1016/j.cell.2022.10.004
  
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sciencedirect.com/science/article/pii/S0092867422013198
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LncRNA CCTT-mediated RNA-DNA and RNA-protein interactions facilitate the recruitment of CENP-C to centromeric DNA during kinetochore assembly

1
1. scibot 04 Nov 2022
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2022.09.022
  
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sciencedirect.com/science/article/pii/S109727652200911X
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GERMLINE GAIN-OF-FUNCTION MMP11 VARIANT RESULTS IN AN AGGRESSIVE FORM OF COLORECTAL CANCER

1
1. scibot 03 Nov 2022
  
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  RRID: CVCL_0291
  
  DOI: 10.1002/ijc.34289
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34289
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Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells

1
1. scibot 03 Nov 2022
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2022.10.005
  
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sciencedirect.com/science/article/pii/S1097276522009625
52.53.155.43 52.53.155.43

ABCC10-mediated Oxaliplatin resistance in colorectal cancer cells was alleviated by intense endoplasmic reticulum stress (ERS) / IRE1α

1
1. scibot 03 Nov 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.21203/rs.3.rs-1947659/v1
  
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52.53.155.43/ee9544f92d24a784e439b5f8ccd0815fd1dd27bc/f0a3133f-5e3c-40fc-b375-09b76f1fe1f4-html.html
Oct 2022
52.53.155.43 52.53.155.43

can-22-1006-html.html

1
1. scibot 27 Oct 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-22-1006
  
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52.53.155.43/c7dd388c408138b6cb565cf3908ca9cf1e84b78d/can-22-1006-html.html
aacrjournals.org aacrjournals.org

Selenium modulates cancer cell response to pharmacologic ascorbate

1
1. scibot 27 Oct 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-22-0408
  
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aacrjournals.org/cancerres/article/82/19/3486/709413/Selenium-Modulates-Cancer-Cell-Response-to
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A microfluidic Braille valve platform for on-demand production, combinatorial screening and sorting of chemically distinct droplets

1
1. scibot 25 Oct 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41596-022-00740-4
  
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nature.com/articles/s41596-022-00740-4
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Cancer-specific T helper shared and neo-epitopes uncovered by expression of the MHC class II master regulator CIITA

1
1. scibot 12 Oct 2022
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2022.111485
  
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sciencedirect.com/science/article/pii/S2211124722013353
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Decreased DNA damage and improved p53 specificity of RITA analogs

1
1. scibot 12 Oct 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/1535-7163.MCT-22-0119
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9538593/
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A selective and orally bioavailable VHL-recruiting PROTAC achieves SMARCA2 degradation in vivo

1
1. scibot 11 Oct 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41467-022-33430-6
  
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nature.com/articles/s41467-022-33430-6
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Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation

1
1. scibot 09 Oct 2022
  
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  Cat# CCL-247
  
  DOI: 10.1016/j.molcel.2022.09.018
  
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sciencedirect.com/science/article/pii/S1097276522009078
Sep 2022
insight.jci.org insight.jci.org

HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1<b>α</b>/ERR<b>α</b> axis

1
1. scibot 30 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1172/jci.insight.159600
  
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insight.jci.org/articles/view/159600
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Anti-metastatic effects of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in colorectal cancer: Regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial-to-mesenchymal transition

1
1. scibot 21 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.phrs.2022.106457
  
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sciencedirect.com/science/article/pii/S1043661822004030
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Special issue “The advance of solid tumor research in China”: Discoidin domain receptor 2 promotes colorectal cancer metastasis by regulating epithelial mesenchymal transition via activating AKT signaling

1
1. scibot 14 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.34227
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34227
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Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

1
1. scibot 11 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.crmeth.2022.100294
  
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sciencedirect.com/science/article/pii/S266723752200176X
Aug 2022
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Substrate spectrum of PPM1D in the cellular response to DNA double-strand breaks

1
1. scibot 27 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2022.104892
  
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sciencedirect.com/science/article/pii/S2589004222011646
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

1
1. scibot 17 Aug 2022
  
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  ATCCCat# CCL-247
  
  DOI: 10.1016/j.celrep.2022.111233
  
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sciencedirect.com/science/article/pii/S2211124722010506
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Systematic study of tissue factor expression in solid tumors

1
1. scibot 16 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/cnr2.1699
  
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onlinelibrary.wiley.com/doi/10.1002/cnr2.1699
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration

1
1. scibot 13 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.3389/fcimb.2022.913815
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9359126/
Jul 2022
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Acetylation of p62 regulates base excision repair through interaction with APE1

1
1. scibot 27 Jul 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.celrep.2022.111116
  
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sciencedirect.com/science/article/pii/S2211124722009226
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Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/1878-0261.13223
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9298677/
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2022.104721
  
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sciencedirect.com/science/article/pii/S2589004222009932
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Exploring the potential of exosomes in diagnosis and drug delivery for PDAC

1
1. scibot 15 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.34195
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34195
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Tumor cell conditioned media drives collagen remodeling via fibroblast and pericyte activation in an in vitro premetastatic niche model

1
1. scibot 08 Jul 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.isci.2022.104645
  
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sciencedirect.com/science/article/pii/S2589004222009178
Jun 2022
academic.oup.com academic.oup.com

MiRNA-Based Therapies for the Treatment of Inflammatory Bowel Disease: What Are We Still Missing?

1
1. scibot 28 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1093/ibd/izac122
  
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academic.oup.com/ibdjournal/advance-article/doi/10.1093/ibd/izac122/6617564
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Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses

1
1. scibot 22 Jun 2022
  
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  ATCCCat# CCL-247
  
  DOI: 10.1016/j.chembiol.2022.05.009
  
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sciencedirect.com/science/article/pii/S245194562200201X
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Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

1
1. scibot 18 Jun 2022
  
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  ATCC#: CCL-247
  
  DOI: 10.1016/j.str.2022.05.019
  
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sciencedirect.com/science/article/pii/S0969212622002283
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Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR

1
1. scibot 15 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2022.110950
  
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sciencedirect.com/science/article/pii/S221112472200732X
www.nature.com www.nature.com

RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition

1
1. scibot 11 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41467-022-30794-7
  
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nature.com/articles/s41467-022-30794-7
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Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids

1
1. scibot 02 Jun 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.celrep.2022.110870
  
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sciencedirect.com/science/article/pii/S2211124722006453
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  ATCCCat#CCL-247
  
  DOI: 10.1016/j.celrep.2022.110851
  
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sciencedirect.com/science/article/pii/S2211124722006246
May 2022
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DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production

1
1. scibot 20 May 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.molcel.2022.04.030
  
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sciencedirect.com/science/article/pii/S1097276522003938
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Whole-genome duplication shapes the aneuploidy landscape of human cancers

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Posttranslational modification of microtubules by the MATCAP detyrosinase

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Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth

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Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

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FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1

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Sister chromatid–sensitive Hi-C to map the conformation of replicated genomes

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Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB

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DNA replication profiling by molecular combing on single DNA fibers

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Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

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Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation

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Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing

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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

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Genetic instability from a single S phase after whole-genome duplication

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MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

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Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide

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Tumor targeting with bacterial Shiga toxin B-subunit in genetic porcine models for colorectal cancer and osteosarcoma

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BPS Publications

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A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

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Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B

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ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
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Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity

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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

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Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer

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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

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Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression

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Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: potential role of ADAM9

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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

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Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

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Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers

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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage

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Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells

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Feedback-regulated transcriptional repression of FBXO31 by c-Myc triggers ovarian cancer tumorigenesis

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NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein

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AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer

1
1. scibot 05 Jan 2022
  
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Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

1
1. scibot 29 Dec 2021
  
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USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1

1
1. scibot 29 Dec 2021
  
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MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

1
1. scibot 22 Dec 2021
  
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Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer

1
1. scibot 16 Dec 2021
  
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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

1
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

1
1. scibot 04 Dec 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.62644
  
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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

1
1. scibot 02 Dec 2021
  
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

1
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Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I

1
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Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition

1
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  CCL-247
  
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

2
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  CCL-247
  
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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
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  DOI: 10.1016/j.bioorg.2021.105505
  
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FEBS Press

1
1. scibot 19 Nov 2021
  
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  CCL-247
  
  DOI: 10.1111/febs.16261
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.16261
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Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation

1
1. scibot 19 Nov 2021
  
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  CCL-247
  
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Short-chain fatty acids activate acetyltransferase p300

1
1. scibot 19 Nov 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.72171
  
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Toward comprehensive imaging of oncolytic viroimmunotherapy

1
1. scibot 18 Nov 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.omto.2021.06.010
  
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Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity

1
1. scibot 18 Nov 2021
  
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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
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  CCL-247
  
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Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

1
1. scibot 10 Nov 2021
  
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  CCL-247
  
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
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  DOI: 10.1016/j.ebiom.2021.103646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
Oct 2021
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Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

1
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator

1
1. scibot 29 Oct 2021
  
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  CCL-247
  
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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

1
1. scibot 27 Oct 2021
  
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XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer

1
1. scibot 23 Oct 2021
  
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  DOI: 10.1038/s41392-021-00761-7
  
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nature.com/articles/s41392-021-00761-7
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USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork

1
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  CCL-247
  
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Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

1
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Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments

1
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  DOI: 10.1016/j.envint.2021.106921
  
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Proteome-wide mapping of short-lived proteins in human cells

1
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Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines

1
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academic.oup.com academic.oup.com

Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions

1
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  RRID:CVCL_0291
  
  DOI: 10.1210/clinem/dgab651
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
Sep 2021
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Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates

1
1. scibot 29 Sep 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.3390/ph14100950
  
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mdpi.com/1424-8247/14/10/950
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Oncogene-dependent sloppiness in mRNA translation

1
1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.09.002
  
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CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase

1
1. scibot 24 Sep 2021
  
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  CCL-247
  
  DOI: 10.1093/nar/gkab805
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
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Alternative microexon splicing by RBFOX2 and PTBP1 is associated with metastasis in colorectal cancer

1
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  DOI: 10.1002/ijc.33758
  
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ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

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Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

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  DOI: 10.1002/cam4.4212
  
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Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer

1
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  CCL-247
  
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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

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REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

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SPT5 stabilization of promoter-proximal RNA polymerase II

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  CCL-247
  
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High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment

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  CCL-247
  
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iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation

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YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

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Entosis is induced by UV radiation.

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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

1
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Untitled document

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Untitled document

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Untitled document

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KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses

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BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination

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Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

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Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

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  CCL-247
  
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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.

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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

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FEBS Press

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination

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  HCT116
  
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

1
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  HCT116
  
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Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis

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1. scibot 31 Jul 2021
  
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  Human colorectal carcinoma HCT116 cells (male)
  
  DOI: 10.1016/j.molcel.2019.10.015
  
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NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor

1
1. scibot 31 Jul 2021
  
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  Human colorectal carcinoma cells: HCT 116 cells
  
  DOI: 10.1016/j.celrep.2019.09.087
  
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sciencedirect.com/science/article/pii/S2211124719312914
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Untitled document

1
1. scibot 31 Jul 2021
  
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  CVCL_0291
  
  DOI: 10.7554/eLife.31326
  
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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

1
1. scibot 31 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2019.03.034
  
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Widespread and Functional RNA Circularization in Localized Prostate Cancer

1
1. scibot 31 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cell.2019.01.025
  
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Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

1
1. scibot 30 Jul 2021
  
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  HCT116
  
  DOI: 10.18632/oncotarget.27159
  
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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
1. scibot 30 Jul 2021
  
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  HCT116
  
  DOI: 10.1016/j.celrep.2019.08.090
  
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
1. scibot 30 Jul 2021
  
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  HCC116
  
  DOI: 10.1016/j.ccell.2019.08.006
  
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The Cancer SENESCopedia: A delineation of cancer cell senescence

1
1. scibot 30 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.109441
  
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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

1
1. scibot 29 Jul 2021
  
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  RRID: CVCL_0291
  
  DOI: 10.1016/j.ebiom.2019.11.011
  
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sciencedirect.com/science/article/pii/S2352396419307522
royalsocietypublishing.org royalsocietypublishing.org

Oncogenic MYC amplifies mitotic perturbations

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1098/rsob.190136
  
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royalsocietypublishing.org/doi/full/10.1098/rsob.190136
onlinelibrary.wiley.com onlinelibrary.wiley.com

Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.32608
  
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onlinelibrary.wiley.com/doi/abs/10.1002/ijc.32608
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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

1
1. scibot 29 Jul 2021
  
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  Human: HCT116
  
  DOI: 10.1016/j.celrep.2019.07.050
  
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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.27301
  
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Untitled document

1
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.24578
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5576923/
elifesciences.org elifesciences.org

Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

2
1. scibot 29 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.32692
  
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2. scibot 27 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.32692
  
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elifesciences.org/articles/32692
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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

1
1. scibot 28 Jul 2021
  
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  HCT-116 colorectal cancer cell line, human
  
  DOI: 10.1016/j.chembiol.2019.04.011
  
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Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

1
1. scibot 27 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cub.2018.10.006
  
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

1
1. scibot 27 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cell.2018.09.051
  
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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

1
1. scibot 27 Jul 2021
  
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  CCL-247
  
  DOI: 10.1038/s41467-017-00678-2
  
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ncbi.nlm.nih.gov/pmc/articles/PMC5605498/
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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
1. scibot 22 Jul 2021
  
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  CVCL_0291
  
  DOI: 10.1016/j.xcrm.2021.100350
  
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CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity

1
1. scibot 20 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2021.06.007
  
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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

1
1. scibot 16 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cmet.2021.06.013
  
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BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells

1
1. scibot 14 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109359
  
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Protein disulfide isomerase inhibits endoplasmic reticulum stress response and apoptosis via its oxidoreductase activity in colorectal cancer

1
1. scibot 11 Jul 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cellsig.2021.110076
  
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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

1
1. scibot 10 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cub.2021.06.030
  
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Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

1
1. scibot 09 Jul 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109311
  
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Jun 2021
cancerres.aacrjournals.org cancerres.aacrjournals.org

STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

1
1. scibot 29 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-20-2874
  
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cancerres.aacrjournals.org/content/81/11/2943
elifesciences.org elifesciences.org

Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

1
1. scibot 17 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.58342
  
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elifesciences.org/articles/58342
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
1. scibot 17 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.61461
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8192123/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

1
1. scibot 17 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.66608
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8195604/
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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

1
1. scibot 16 Jun 2021
  
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  CCL-247
  
  DOI: 10.1016/j.crmeth.2021.100015
  
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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

1
1. scibot 16 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.3390/cancers13112840
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8201054/
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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

1
1. scibot 12 Jun 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cmet.2021.05.016
  
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TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

1
1. scibot 02 Jun 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cell.2021.04.047
  
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Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis

1
1. scibot 02 Jun 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.canlet.2021.05.033
  
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sciencedirect.com/science/article/pii/S0304383521002573
May 2021
elifesciences.org elifesciences.org

Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

1
1. scibot 26 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.65700
  
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elifesciences.org/articles/65700
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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

1
1. scibot 20 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.33562
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33562
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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer

1
1. scibot 20 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.33561
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33561
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Immuno-PET Molecular Imaging of RANKL in Cancer

1
1. scibot 19 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.3390/cancers13092166
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8124205/
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Grade-targeted nanoparticles for improved hypoxic tumor microenvironment and enhanced photodynamic cancer therapy

1
1. scibot 10 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.2217/nnm-2020-0096
  
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futuremedicine.com/doi/abs/10.2217/nnm-2020-0096
cancerres.aacrjournals.org cancerres.aacrjournals.org

Survivin Expression is Differentially Regulated by a Selective Crosstalk between Rbm38 and miRNAs let-7b or miR-203a

1
1. scibot 10 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-20-3157
  
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cancerres.aacrjournals.org/content/81/7/1827
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BPS Publications

1
1. scibot 10 May 2021
  
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  CVCL_0291
  
  DOI: 10.1111/bph.15372
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15372
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Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

1
1. scibot 07 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2020.06.027
  
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sciencedirect.com/science/article/pii/S1097276520304299
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POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

1
1. scibot 07 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2020.05.012
  
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sciencedirect.com/science/article/pii/S1097276520303130
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Synergistic antitumor activity of DHA and JQ1 in colorectal carcinoma

1
1. scibot 06 May 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.ejphar.2020.173500
  
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sciencedirect.com/science/article/pii/S0014299920305926
febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com

FEBS Press

1
1. scibot 06 May 2021
  
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  CVCL_0291
  
  DOI: 10.1002/1878-0261.12953
  
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febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.12953
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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

1
1. scibot 01 May 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cmet.2021.03.003
  
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sciencedirect.com/science/article/pii/S1550413121001108
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

1
1. scibot 01 May 2021
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2021.04.009
  
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sciencedirect.com/science/article/pii/S1097276521003142
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The Source of Glycolytic Intermediates in Mammalian Tissues

1
1. scibot 01 May 2021
  
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  CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.020
  
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sciencedirect.com/science/article/pii/S1550413120307282
Apr 2021
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Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

1
1. scibot 30 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.002
  
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sciencedirect.com/science/article/pii/S1550413120306574
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Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

1
1. scibot 29 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1007/s00018-021-03818-6
  
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link.springer.com/article/10.1007/s00018-021-03818-6
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Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

1
1. scibot 28 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108999
  
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sciencedirect.com/science/article/pii/S2211124721003132
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Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

1
1. scibot 28 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2021.04.004
  
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sciencedirect.com/science/article/pii/S2451945621001598
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Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

1
1. scibot 28 Apr 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
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sciencedirect.com/science/article/pii/S2451945620304736
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Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

1
1. scibot 27 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.chembiol.2020.07.017
  
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sciencedirect.com/science/article/pii/S2451945620302907
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Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

1
1. scibot 24 Apr 2021
  
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  CCL-247
  
  DOI: 10.1016/j.cell.2020.07.030
  
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sciencedirect.com/science/article/pii/S0092867420309387

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