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  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Antibody-Drug Conjugates Targeting the EGFR Ligand Epiregulin Elicit Robust Anti-Tumor Activity in Colorectal Cancer
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    1. scibot 21 Dec 2024
      RRID:CVCL_0291

      DOI: 10.1101/2024.02.20.581056

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    pmc.ncbi.nlm.nih.gov/articles/PMC11601497/
  3. www.sciencedirect.com www.sciencedirect.com
    DDX39A resolves replication fork-associated RNA-DNA hybrids to balance fork protection and cleavage for genomic stability maintenance
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S1097276524009547
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    TurboCas: A method for locus-specific labeling of genomic regions and isolating their associated protein interactome
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    1. scibot 21 Dec 2024
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    sciencedirect.com/science/article/pii/S1097276524009122
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    RPF2 and CARM1 cooperate to enhance colorectal cancer metastasis via the AKT/GSK-3β signaling pathway.
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    1. scibot 19 Dec 2024
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    sciencedirect.com/science/article/pii/S0014482724004658
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    Synergistic anticancer activity of HSP70 and HSF1 inhibitors in colorectal cancer cells: A new strategy for combination therapy
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    1. scibot 17 Dec 2024
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    sciencedirect.com/science/article/pii/S0925443924006240
  7. Dec 2024
  8. www.sciencedirect.com www.sciencedirect.com
    Molecular tag for promoting N-glycan maturation in the cargo receptor-mediated secretion pathway
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    sciencedirect.com/science/article/pii/S2589004224026841
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    UGGT1-mediated reglucosylation of N-glycan competes with ER-associated degradation of unstable and misfolded glycoproteins
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    1. scibot 13 Dec 2024
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      DOI: 10.7554/eLife.93117

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    pmc.ncbi.nlm.nih.gov/articles/PMC11630818/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
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    1. scibot 13 Dec 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11632859/
  11. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Epigenetic Suppression of miR-137 Induces RNF4 Expression, Facilitating Wnt Signaling in Colorectal Cancer
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    1. scibot 13 Dec 2024
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      DOI: 10.1002/mc.23859

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    onlinelibrary.wiley.com/doi/full/10.1002/mc.23859
  12. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    1. scibot 12 Dec 2024
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    febs.onlinelibrary.wiley.com/doi/10.1111/febs.17350
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    CRL3ARMC5 ubiquitin ligase and Integrator phosphatase form parallel mechanisms to control early stages of RNA Pol II transcription
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    1. scibot 12 Dec 2024
      ATCCCCL-247

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    sciencedirect.com/science/article/pii/S1097276524009493
  14. link.springer.com link.springer.com
    LncRNA DANCR-V1 is a novel regulator of Wnt/β-catenin and TGF-β1/SMAD signaling pathways in colorectal cancer: an in vitro and in silico study
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    1. scibot 12 Dec 2024
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    link.springer.com/article/10.1007/s11033-024-10128-0
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    Inhibiting de novo lipogenesis identifies a therapeutic vulnerability in therapy-resistant colorectal cancer
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    1. scibot 12 Dec 2024
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    sciencedirect.com/science/article/pii/S2213231724004361
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    Circular RNAs trigger nonsense-mediated mRNA decay
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    1. scibot 12 Dec 2024
      RRID:CVCL_0291

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    sciencedirect.com/science/article/pii/S109727652400947X
  17. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Glucocorticoid promotes metastasis of colorectal cancer via co-regulation of glucocorticoid receptor and TET2
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    1. scibot 12 Dec 2024
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    onlinelibrary.wiley.com/doi/10.1002/ijc.35285
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    Optimized reporters for multiplexed detection of transcription factor activity
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    1. scibot 10 Dec 2024
      RRID:CVCL_0291

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    sciencedirect.com/science/article/pii/S2405471224003120
  19. www.sciencedirect.com www.sciencedirect.com
    DNA hypomethylation promotes UHRF1-and SUV39H1/H2-dependent crosstalk between H3K18ub and H3K9me3 to reinforce heterochromatin states
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    1. scibot 05 Dec 2024
      ATCCCCL-247

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    sciencedirect.com/science/article/pii/S1097276524009146
  20. www.sciencedirect.com www.sciencedirect.com
    p53 induces circFRMD4A to suppress cancer development through glycolytic reprogramming and cuproptosis
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    1. scibot 05 Dec 2024
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    sciencedirect.com/science/article/pii/S1097276524009183
  21. journals.sagepub.com journals.sagepub.com
    Biglycan promotes tumour proliferation and invasion in human colon cancers
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    1. scibot 03 Dec 2024
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      DOI: 10.1177/03000605241300067

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  22. www.nature.com www.nature.com
    The dysadherin/MMP9 axis modifies the extracellular matrix to accelerate colorectal cancer progression
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    1. scibot 03 Dec 2024
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    nature.com/articles/s41467-024-54920-9
  23. www.sciencedirect.com www.sciencedirect.com
    Activity-dependent COX-2 proteolysis modulates aerobic respiration and proliferation in a prostaglandin-independent manner
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    1. scibot 02 Dec 2024
      CCL-247

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    sciencedirect.com/science/article/pii/S2589004224026282
  24. www.sciencedirect.com www.sciencedirect.com
    B7H6 is the predominant activating ligand driving natural killer cell-mediated killing in patients with liquid tumours: evidence from clinical, in silico, in vitro, and in vivo studies
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    1. scibot 02 Dec 2024
      CVCL_0291

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    sciencedirect.com/science/article/pii/S235239642400495X
  25. Nov 2024
  26. pubs.acs.org pubs.acs.org
    Evaluation of the Combinatory Anticancer Effect of Chemotherapeutic Compounds and Prodigiosin against HCT-116, LoVo, and A549 Cell lines
    1
    1. scibot 29 Nov 2024
      RRID: CVCL_0291

      DOI: 10.1021/acsomega.4c04760

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    pubs.acs.org/doi/10.1021/acsomega.4c04760
  27. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone-acetyl epigenome regulates TGF-β pathway-associated chemoresistance in colorectal cancer
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    1. scibot 26 Nov 2024
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    pmc.ncbi.nlm.nih.gov/articles/PMC11585898/
  28. www.sciencedirect.com www.sciencedirect.com
    Targeting the aminopeptidase ERAP enhances antitumor immunity by disrupting the NKG2A-HLA-E inhibitory checkpoint
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    sciencedirect.com/science/article/pii/S107476132400493X
  29. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Inter-chromosomal contacts demarcate genome topology along a spatial gradient
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    pmc.ncbi.nlm.nih.gov/articles/PMC11557711/
  30. www.sciencedirect.com www.sciencedirect.com
    Recognition of BACH1 quaternary structure degrons by two F-box proteins under oxidative stress
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  31. 52.53.155.43 52.53.155.43
    mcr-24-0433-html.html
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  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Replication stress induces POLQ-mediated structural variant formation throughout common fragile sites after entry into mitosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11541566/
  33. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bidirectional signals generated by Siglec-7 and its crucial ligand tri-sialylated T to escape of cancer cells from immune surveillance
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    pmc.ncbi.nlm.nih.gov/articles/PMC11539641/
  34. Oct 2024
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Combined Oxygen-Enhanced MRI and Perfusion Imaging Detect Hypoxia Modification from Banoxantrone and Atovaquone and Track Their Differential Mechanisms of Action
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443776/
  36. www.biorxiv.org www.biorxiv.org
    Metabolic mapping of the human solute carrier superfamily
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    biorxiv.org/content/10.1101/2024.09.23.614124v1
  37. aacrjournals.org aacrjournals.org
    Overproduction of Gastrointestinal 5-HT Promotes Colitis-Associated Colorectal Cancer Progression via Enhancing NLRP3 Inflammasome Activation
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      DOI: 10.1158/2326-6066.CIR-20-1043

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    aacrjournals.org/cancerimmunolres/article/9/9/1008/666146/Overproduction-of-Gastrointestinal-5-HT-Promotes
  38. aacrjournals.org aacrjournals.org
    2-Hydroxylation of Fatty Acids Represses Colorectal Tumorigenesis and Metastasis via the YAP Transcriptional Axis
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      DOI: 10.1158/0008-5472.CAN-20-1517

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    aacrjournals.org/cancerres/article/81/2/289/649623/2-Hydroxylation-of-Fatty-Acids-Represses
  39. www.sciencedirect.com www.sciencedirect.com
    Mitotic ER-mitochondria contact enhances mitochondrial Ca2+ influx to promote cell division
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    sciencedirect.com/science/article/pii/S2211124724011458
  40. Sep 2024
  41. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    CASCADES, a novel SOX2 super-enhancer-associated long noncoding RNA, regulates cancer stem cell specification and differentiation in glioblastoma
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      DOI: 10.1002/1878-0261.13735

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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13735
  42. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13708
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Ctnnb1 enhancer transcriptionally regulates Wnt signaling dosage to balance homeostasis and tumorigenesis of intestinal epithelia
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    1. scibot 27 Sep 2024
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      DOI: 10.7554/eLife.98238

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    ncbi.nlm.nih.gov/pmc/articles/PMC11424096/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TRAP1 modulates mitochondrial biogenesis via PGC-1α/TFAM signalling pathway in colorectal cancer cells
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    1. scibot 26 Sep 2024
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      DOI: 10.1007/s00109-024-02479-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC11416412/
  45. www.sciencedirect.com www.sciencedirect.com
    Fusobacterium nucleatum facilitates anti-PD-1 therapy in microsatellite stable colorectal cancer
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    sciencedirect.com/science/article/pii/S1535610824003180
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Novel immunotherapeutics against LGR5 to target multiple cancer types
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      DOI: 10.1038/s44321-024-00121-2

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    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
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    Enhancing efficacy of the MEK inhibitor trametinib with paclitaxel in KRAS-mutated colorectal cancer
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    14-3-3σ restricts YY1 to the cytoplasm, promoting therapy resistance, and tumor progression in colorectal cancer
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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  51. www.cell.com www.cell.com
    TEX264 drives selective autophagy of DNA lesions to promote DNA repair and cell survival
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    Comprehensive Proteogenomic Profiling Reveals the Molecular Characteristics of Colorectal Cancer at Distinct Stages of Progression
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    IDO1 inhibitors are synergistic with CXCL10 agonists in inhibiting colon cancer growth
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    Synergistic Anti-tumorigenic Effect of Diosmetin in Combination with 5-Fluorouracil on Human Colon Cancer Xenografts in Nude Mice
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    Five miRNAs identified in fucosylated extracellular vesicles as non-invasive diagnostic signatures for hepatocellular carcinoma
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    Dual function of PHF16 in reinstating homeostasis of murine intestinal epithelium after crypt regeneration
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    RNA interacts with topoisomerase I to adjust DNA topology
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Jianpi Jiedu Recipe Inhibits Proliferation through Reactive Oxygen Species-Induced Incomplete Autophagy and Reduces PD-L1 Expression in Colon Cancer
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  60. www.biorxiv.org www.biorxiv.org
    Discovery of Z1362873773: A Novel Fascin Inhibitor from a Large Chemical Library for Colorectal Cancer
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  62. www.sciencedirect.com www.sciencedirect.com
    CCL19-producing fibroblasts promote tertiary lymphoid structure formation enhancing anti-tumor IgG response in colorectal cancer liver metastasis
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    Integrative plasma and fecal metabolomics identify functional metabolites in adenoma-colorectal cancer progression and as early diagnostic biomarkers
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  64. link.springer.com link.springer.com
    Iron Overloading Potentiates the Antitumor Activity of 5-Fluorouracil by Promoting Apoptosis and Ferroptosis in Colorectal Cancer Cells
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  65. f1000research.com f1000research.com
    F1000Research Article: Unraveling the Interplay of Autophagy Genes and KLF3/KLF8 in Colorectal Cancer Metastasis: A Bioinformatics and cellular Exploration.
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  66. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HTS384 NCI60: The Next Phase of the NCI60 Screen
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  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MMP‐9‐dependent proteolysis of the histone H3 N‐terminal tail: a critical epigenetic step in driving oncogenic transcription and colon tumorigenesis
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  69. onlinelibrary.wiley.com onlinelibrary.wiley.com
    EEF1D stabilized by SRSF9 promotes colorectal cancer via enhancing the proliferation and metastasis
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  70. www.sciencedirect.com www.sciencedirect.com
    BCAA-producing Clostridium symbiosum promotes colorectal tumorigenesis through the modulation of host cholesterol metabolism
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  71. www.cell.com www.cell.com
    Peptostreptococcus stomatis promotes colonic tumorigenesis and receptor tyrosine kinase inhibitor resistance by activating ERBB2-MAPK
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  72. 52.53.155.43 52.53.155.43
    The Natural Alkaloid (-)- N-Hydroxyapiosporamide Suppresses Colorectal Tumor Progression as an NF-κB Pathway Inhibitor by Targeting the TAK1-TRAF6 Complex
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  73. 52.53.155.43 52.53.155.43
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  74. bmccancer.biomedcentral.com bmccancer.biomedcentral.com
    Intense endoplasmic reticulum stress (ERS) / IRE1α enhanced Oxaliplatin efficacy by decreased ABCC10 in colorectal cancer cells
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Small-molecule NSC59984 induces mutant p53 degradation through a ROS-ERK2-MDM2 axis in cancer cells
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  76. jeccr.biomedcentral.com jeccr.biomedcentral.com
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    Therapy-induced DNA methylation inactivates MCT1 and renders tumor cells vulnerable to MCT4 inhibition
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  78. www.mdpi.com www.mdpi.com
    Targeting AKT/mTOR and Bcl-2 for Autophagic and Apoptosis Cell Death in Lung Cancer: Novel Activity of a Polyphenol Compound
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  79. www.embopress.org www.embopress.org
    Unexpected PD‐L1 immune evasion mechanism in TNBC, ovarian, and other solid tumors by DR5 agonist antibodies
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  80. www.cell.com www.cell.com
    In Vivo Evidence for Serine Biosynthesis-Defined Sensitivity of Lung Metastasis, but Not of Primary Breast Tumors, to mTORC1 Inhibition
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    Membrane Damage during Ferroptosis Is Caused by Oxidation of Phospholipids Catalyzed by the Oxidoreductases POR and CYB5R1
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  82. www.mdpi.com www.mdpi.com
    Diketopiperazine-Based, Flexible Tadalafil Analogues: Synthesis, Crystal Structures and Biological Activity Profile
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  83. Jul 2024
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    Translocational attenuation mediated by the PERK-SRP14 axis is a protective mechanism of unfolded protein response
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    Upregulation of TET2 and Resistance to DNA Methyltransferase (DNMT) Inhibitors in DNMT1-Deleted Cancer Cells
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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterising replisome disassembly in human cells
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  87. www.sciencedirect.com www.sciencedirect.com
    FANCM promotes PARP inhibitor resistance by minimizing ssDNA gap formation and counteracting resection inhibition
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    Base-resolution m5C profiling across the mammalian transcriptome by bisulfite-free enzyme-assisted chemical labeling approach
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      DOI: 10.1016/j.molcel.2024.06.021

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    sciencedirect.com/science/article/pii/S1097276524005288
  89. www.sciencedirect.com www.sciencedirect.com
    Proteomic analysis reveals a PLK1-dependent G2/M degradation program and a role for AKAP2 in coordinating the mitotic cytoskeleton
    1
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      RRID:CVCL_0291

      DOI: 10.1016/j.celrep.2024.114510

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  90. www.sciencedirect.com www.sciencedirect.com
    RNA 5-methylcytosine marks mitochondrial double-stranded RNAs for degradation and cytosolic release
    1
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  91. www.sciencedirect.com www.sciencedirect.com
    Identification and characterization of TM4SF1+ tumor self-seeded cells
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  92. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/full/10.1111/bph.16489
  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DHODH inhibition enhances the efficacy of immune checkpoint blockade by increasing cancer cell antigen presentation
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      CCL-247

      DOI: 10.7554/eLife.87292

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  94. www.cell.com www.cell.com
    A mammalian model reveals inorganic polyphosphate channeling into the nucleolus and induction of a hyper-condensate state
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      CVCL_0291

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    cell.com/cell-reports-methods/fulltext/S2667-2375(24)00179-6
  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor invasiveness is regulated by the concerted function of APC, formins and Arp2/3 complex
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  96. Jun 2024
  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Illuminating Dark Chemical Matter Using the Cell Painting Assay
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  98. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Comparing in vitro cytotoxic drug sensitivity in colon and pancreatic cancer using 2D and 3D cell models: Contrasting viability and growth inhibition in clinically relevant dose and repeated drug cycles
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      CVCL_0291

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  99. 52.53.155.43 52.53.155.43
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  100. www.biorxiv.org www.biorxiv.org
    POLQ mediates replication-stress induced structural variant formation throughout common fragile sites during mitosis
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  101. www.science.org www.science.org
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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  102. www.sciencedirect.com www.sciencedirect.com
    De novo and salvage purine synthesis pathways across tissues and tumors
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  103. www.sciencedirect.com www.sciencedirect.com
    Homeostatic coordination of cellular phosphate uptake and efflux requires an organelle-based receptor for the inositol pyrophosphate IP8
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      CCL-247

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bacillamide D produced by Bacillus cereus from the mouse intestinal bacterial collection (miBC) is a potent cytotoxin in vitro
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  105. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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  106. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated analysis of colorectal cancer metastasis identifies characteristics of tumor cell during metastasis
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  107. May 2024
  108. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chloroquine-induced DNA damage synergizes with DNA repair inhibitors causing cancer cell death
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      DOI: 10.3389/fonc.2024.1390518

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  110. pubs.acs.org pubs.acs.org
    Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand
    2
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      HCT-116

      DOI: 10.1021/acs.inorgchem.3c03801

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      CVCL_427

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  111. link.springer.com link.springer.com
    Regulation of human microglial gene expression and function via RNAase-H active antisense oligonucleotides in vivo in Alzheimer’s disease
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      CVCL_0291

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  112. www.tandfonline.com www.tandfonline.com
    Palindromic carbazole derivatives: unveiling their antiproliferative effect via topoisomerase II catalytic inhibition and apoptosis induction
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      CVCL_427

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  113. 52.53.155.43 52.53.155.43
    Everolimus exerts anticancer effects through inhibiting the interaction of matrix metalloproteinase-7 with syndecan-2 in colon cancer cells
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    52.53.155.43/76598b44d554c4165a9f84a25bc34c671709ff41/lee-et-al-2024-everolimus-exerts-anticancer-effects-through-inhibiting-the-interaction-of-matrix-metalloproteinase-7-html.html
  114. www.sciencedirect.com www.sciencedirect.com
    mTORC1-CTLH E3 ligase regulates the degradation of HMG-CoA synthase 1 through the Pro/N-degron pathway
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  115. 52.53.155.43 52.53.155.43
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  116. aacrjournals.org aacrjournals.org
    NRAS mutant dictates AHCYL1-governed ER calcium homeostasis for melanoma tumor growth
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  117. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Hippo pathway terminal effector TAZ/WWTR1 mediates oxaliplatin sensitivity in p53 proficient colon cancer cells
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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Onvansertib in Combination with FOLFIRI and Bevacizumab in Second-line Treatment of KRAS-mutant Metastatic Colorectal Cancer: A Phase 1b Clinical Study
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      RRID:CVCL_0291

      DOI: 10.1158/1078-0432.CCR-23-3053

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  119. www.mdpi.com www.mdpi.com
    Systemic DNA Damage and Repair Activity Vary by Race in Breast Cancer Survivors
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  120. www.sciencedirect.com www.sciencedirect.com
    A novel Senescence-Based prognostic model unveils tumor interactions and drug resistance in colorectal cancer
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  121. 52.53.155.43 52.53.155.43
    Pathway metabolite ratios reveal distinctive glutamine metabolism in a subset of proliferating cells
    2
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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synergy of EGFR and AURKA Inhibitors in KRAS-mutated Non–small Cell Lung Cancers
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  123. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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  124. 52.53.155.43 52.53.155.43
    2024.04.30.591961v1.full-html.html
    1
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  125. 52.53.155.43 52.53.155.43
    SIRT1 mediates the antagonism of Wnt/β-catenin pathway by vitamin D in colon carcinoma cells
    1
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      RRID:CVCL_029

      DOI: 10.1101/2024.01.21.576539

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Correcting 4sU induced quantification bias in nucleotide conversion RNA-seq data
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      DOI: 10.1093/nar/gkae120

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  127. Apr 2024
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  129. www.embopress.org www.embopress.org
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  130. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Type I interferon regulation by USP18 is a key vulnerability in cancer
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    A p85 isoform switch enhances PI3K activation on endosomes by a MAP4- and PI3P-dependent mechanism
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    RAD51 restricts DNA over-replication from re-activated origins
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  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Early recovery of proteasome activity in cells pulse-treated with proteasome inhibitors is independent of DDI2
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    Global, site-resolved analysis of ubiquitylation occupancy and turnover rate reveals systems properties
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  135. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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  136. www.cell.com www.cell.com
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  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Discovery of the sEH Inhibitor Epoxykynin as a Potent Kynurenine Pathway Modulator
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    The SPATA5-SPATA5L1 ATPase complex directs replisome proteostasis to ensure genome integrity
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    p53 rapidly restructures 3D chromatin organization to trigger a transcriptional response
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  140. Mar 2024
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    Discovery of YAP1/TAZ pathway inhibitors through phenotypic screening with potent anti-tumor activity via blockade of Rho-GTPase signaling
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    Eosinophils exhibit a unique transcriptional signature and increased sensitivity to IL-3-induced activation in response to colorectal cancer cells
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    Reduced chemokine C‐C motif ligand 1 expression may negatively regulate colorectal cancer progression at liver metastatic sites
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    A gut-derived hormone regulates cholesterol metabolism
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    RAD51 restricts DNA over-replication from re-activated origins
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    RAD51 restricts DNA over-replication from re-activated origins
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    KRAS silencing impacts chromatin organization and transcriptional activity in colorectal cancer cells
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    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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    MTOR modulation induces selective perturbations in histone methylation which influence the anti-proliferative effects of mTOR inhibitors
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    Loss of STIM2 in colorectal cancer drives growth and metastasis through metabolic reprogramming and PERK-ATF4 endoplasmic reticulum stress pathway
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    A synergistic two-drug therapy specifically targets a DNA repair dysregulation that occurs in p53-deficient colorectal and pancreatic cancers
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  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of a First-in-Class Small Molecule Inhibitor of the eIF4E-RBM38 Complex that Enhances wild-type p53 Protein Translation for Tumor Growth Suppression
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    Specialized replication mechanisms maintain genome stability at human centromeres
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  157. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    GNAS mutation inhibits growth and induces phosphodiesterase 4D expression in colorectal cancer cell lines
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    SIN3A histone deacetylase action counteracts MUS81 to promote stalled fork stability
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    Stratification of Colorectal Patients Based on Survival Analysis Shows the Value of Consensus Molecular Subtypes and Reveals the CBLL1 Gene as a Biomarker of CMS2 Tumours
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  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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  163. link.springer.com link.springer.com
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    Locus-level L1 DNA methylation profiling reveals the epigenetic and transcriptional interplay between L1s and their integration sites
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    Anti-tumor immunotherapy using engineered bacterial outer membrane vesicles fused to lysosome-targeting chimeras mediated by transferrin receptor
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    Locked Nucleic Acid Oligonucleotides Facilitate RNA•LNA-RNA Triple-Helix Formation and Reduce MALAT1 Levels
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      DOI: 10.3390/ijms25031630

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  167. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    Autophagy-dependent alternative splicing of ribosomal protein S24 produces a more stable isoform that aids in hypoxic cell survival
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  168. Jan 2024
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A critical threshold of MCM10 is required to maintain genome stability during differentiation of induced pluripotent stem cells into natural killer cells
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  170. www.nature.com www.nature.com
    Non-alcoholic fatty liver disease promotes liver metastasis of colorectal cancer via fatty acid synthase dependent EGFR palmitoylation
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  171. www.cell.com www.cell.com
    p53-responsive CMBL reprograms glucose metabolism and suppresses cancer development by destabilizing phosphofructokinase PFKP
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    cell.com/cell-reports/abstract/S2211-1247(23)01438-9
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MIIP downregulation drives colorectal cancer progression through inducing peri-cancerous adipose tissue browning
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  173. www.sciencedirect.com www.sciencedirect.com
    Histone lactylation inhibits RARγ expression in macrophages to promote colorectal tumorigenesis through activation of TRAF6-IL-6-STAT3 signaling
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  174. www.sciencedirect.com www.sciencedirect.com
    Discovery of galectin-8 as an LILRB4 ligand driving M-MDSCs defines a class of antibodies to fight solid tumors
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  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The effector program of human CD8 T cells supports tissue remodeling
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    Tolerance to colibactin correlates with homologous recombination proficiency and resistance to irinotecan in colorectal cancer cells
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    A comprehensive clinically informed map of dependencies in cancer cells and framework for target prioritization
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  178. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 NSP14 MTase activity is critical for inducing canonical NF-κB activation
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  179. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The feedback loop of EFTUD2/c-MYC impedes chemotherapeutic efficacy by enhancing EFTUD2 transcription and stabilizing c-MYC protein in colorectal cancer
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  180. Dec 2023
  181. www.sciencedirect.com www.sciencedirect.com
    Metabolic regulation of homologous recombination repair by MRE11 lactylation
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  182. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting Aggressive B-cell Lymphomas through Pharmacological Activation of the Mitochondrial Protease OMA1
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  183. www.sciencedirect.com www.sciencedirect.com
    Irreversible inhibition of TRF2TRFH recruiting functions by a covalent cyclic peptide induces telomeric replication stress in cancer cells
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  184. www.sciencedirect.com www.sciencedirect.com
    Proteomic characterization of the colorectal cancer response to chemoradiation and targeted therapies reveals potential therapeutic strategies
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  185. www.tandfonline.com www.tandfonline.com
    Identification of putative allosteric inhibitors of BCKDK via virtual screening and biological evaluation
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      DOI: 10.1080/14756366.2023.2290458

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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RPF2 mediates the CARM1‑MYCN axis to promote chemotherapy resistance in colorectal cancer cells
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      DOI: 10.3892/or.2023.8670

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  187. pubs.acs.org pubs.acs.org
    Selective Tumor Hypoxia Targeting Using M75 Antibody Conjugated Photothermally Active MoOx Nanoparticles
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      CCL-247, ATCC

      DOI: 10.1021/acsomega.3c01934

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  188. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Transcript CD81-215 may be a long noncoding RNA of stromal origin with tumor-promoting role in colon cancer
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      DOI: 10.1002/cbf.3890

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  189. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metastatic or xenograft colorectal cancer induce divergent anabolic deficits and pro-inflammatory effectors of muscle wasting in a tumor-type dependent manner
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      DOI: 10.1152/japplphysiol.00247.2022

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  190. www.nature.com www.nature.com
    Revealing the tumor suppressive sequence within KL1 domain of the hormone Klotho
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  191. www.biorxiv.org www.biorxiv.org
    A novel antagonist of the CCL5/CCR5 axis suppresses the tumor growth and metastasis of triple-negative breast cancer by CCR5-YAP1 regulation
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      DOI: 10.1101/2023.11.15.567291

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  192. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Revisiting the role of endogenous STAT3 in HPV-positive cervical cancer cells
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  193. Nov 2023
  194. www.sciencedirect.com www.sciencedirect.com
    RNF14-dependent atypical ubiquitylation promotes translation-coupled resolution of RNA-protein crosslinks
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  195. www.sciencedirect.com www.sciencedirect.com
    Targeted perturbation of signaling-driven condensates
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  196. link.springer.com link.springer.com
    Cell-specific modulation of mitochondrial respiration and metabolism by the pro-apoptotic Bcl-2 family members Bax and Bak
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  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Multiple cullin-associated E3 ligases regulate cyclin D1 protein stability
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  198. www.sciencedirect.com www.sciencedirect.com
    Anti-tumor effect of PD-L1-targeting antagonistic aptamer-ASO delivery system with dual inhibitory function in immunotherapy
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  199. www.sciencedirect.com www.sciencedirect.com
    HRS mediates tumor immune evasion by regulating proteostasis-associated interferon pathway activation
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  200. www.sciencedirect.com www.sciencedirect.com
    Deficiency of BCAT2-mediated branched-chain amino acid catabolism promotes colorectal cancer development
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    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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  202. link.springer.com link.springer.com
    TCOF1 promotes the colorectal cancer progression by stabilizing β-catenin
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    In vivo bioluminescence imaging of labile iron in xenograft models and liver using FeAL-1, an iron-activatable form of D-luciferin
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  204. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Matrix stiffness triggers lipid metabolic crosstalk between tumor and stromal cells to mediate bevacizumab resistance in colorectal cancer liver metastases
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP1 Expression Driven by EWS::FLI1 Transcription Factor Stabilizes Survivin and Mitigates Replication Stress in Ewing Sarcoma
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