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  1. Aug 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumor Vessel Normalization via PFKFB3 Inhibition Alleviates Hypoxia and Increases Tumor Necrosis in Rectal Cancer upon Radiotherapy
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    1. scibot 21 Aug 2024
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      DOI: 10.1158/2767-9764.CRC-24-0077

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    ncbi.nlm.nih.gov/pmc/articles/PMC11310748/
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    In vitro comparison of viral replication and cytopathology induced by SARS-CoV-2 variants
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      DOI: 10.1099/acmi.0.000716.v3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11316578/
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    Schlafen 11 further sensitizes BRCA-deficient cells to PARP inhibitors through single-strand DNA gap accumulation behind replication forks
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    1. scibot 21 Aug 2024
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      DOI: 10.1038/s41388-024-03094-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC11315672/
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    BDNF-dependent nano-organization of Neogenin and the WAVE Regulatory Complex promotes actin remodelling in dendritic spines
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    1. scibot 21 Aug 2024
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      DOI: 10.1016/j.isci.2024.110621

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    sciencedirect.com/science/article/pii/S2589004224018467
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    Functional genomic analysis of genes important for Candida albicans fitness in diverse environmental conditions
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    sciencedirect.com/science/article/pii/S2211124724009409
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    An actomyosin network organizes niche morphology and responds to feedback from recruited stem cells
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      DOI: 10.1016/j.cub.2024.07.041

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    sciencedirect.com/science/article/pii/S0960982224009448
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    PKD1 gene mutation and ultrasonographic characterization in cats with renal cysts
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      DOI: 10.12688/f1000research.134906.3

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301141/
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    Glucagon infusion alters the circulating metabolome and urine amino acid excretion in dogs
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      DOI: 10.1530/JOE-24-0051

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301426/
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    Smooth muscle electromyography for detecting major alterations in the estrus cycle in rats
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      DOI: 10.1371/journal.pone.0307932

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    ncbi.nlm.nih.gov/pmc/articles/PMC11309437/
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    Amitriptyline and cholecalciferol amend hippocampal histological structure and myelination during stress in Wistar rats via regulating miR200/BMP4/Olig-2 signaling
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    1. scibot 21 Aug 2024
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      DOI: 10.1002/cbin.12200

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    onlinelibrary.wiley.com/doi/10.1002/cbin.12200
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    Structural requirements for activity of Mind bomb1 in Notch signaling
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    1. scibot 20 Aug 2024
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      DOI: 10.1016/j.str.2024.07.011

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    sciencedirect.com/science/article/pii/S0969212624002740
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    Oligodendrocyte precursor cell-derived exosomes combined with cell therapy promote clinical recovery by immunomodulation and gliosis attenuation
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      DOI: 10.3389/fncel.2024.1413843

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    ncbi.nlm.nih.gov/pmc/articles/PMC11301646/
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    Sphingosine-1 phosphate receptor 1 (S1PR1) expression maintains stemness of acute myeloid leukemia stem cells
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      DOI: 10.1016/j.canlet.2024.217158

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    sciencedirect.com/science/article/pii/S0304383524005536
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    Hierarchical tricarboxylic acid cycle regulation by hepatocyte arginase 2 links the urea cycle to oxidative metabolism
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      DOI: 10.1016/j.cmet.2024.07.007

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    sciencedirect.com/science/article/pii/S155041312400278X
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    A molecular pathway for cancer cachexia-induced muscle atrophy revealed at single-nucleus resolution
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      DOI: 10.1016/j.celrep.2024.114587

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    sciencedirect.com/science/article/pii/S2211124724009161
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    Small GTPase ActIvitY ANalyzing (SAIYAN) system: A method to detect GTPase activation in living cells
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      RRID:SCR_002798

      DOI: 10.1083/jcb.202403179

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      DOI: 10.1083/jcb.202403179

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  18. www.mdpi.com www.mdpi.com
    Regulatory Role and Cytoprotective Effects of Exogenous Recombinant SELENOM under Ischemia-like Conditions and Glutamate Excitotoxicity in Cortical Cells In Vitro
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      DOI: 10.3390/biomedicines12081756

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  19. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    Age-, region-, and day/night-related variation of the chloride reversal potential in the rat suprachiasmatic nucleus
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    1. scibot 20 Aug 2024
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      DOI: 10.1002/jnr.25373

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    pubmed.ncbi.nlm.nih.gov/39101281/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adipose microenvironment promotes hypersialylation of ovarian cancer cells
    1
    1. scibot 19 Aug 2024
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      DOI: 10.3389/fonc.2024.1432333

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    ncbi.nlm.nih.gov/pmc/articles/PMC11299042/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Microplastic exposure disturbs sleep structure, reduces lifespan, and decreases ovary size in Drosophila melanogaster
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    1. scibot 19 Aug 2024
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      DOI: 10.24272/j.issn.2095-8137.2024.038

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    ncbi.nlm.nih.gov/pmc/articles/PMC11298679/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncolytic adenovirus Delta-24-RGD in combination with ONC201 induces a potent antitumor response in pediatric high-grade and diffuse midline glioma models
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1093/neuonc/noae066

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    ncbi.nlm.nih.gov/pmc/articles/PMC11300018/
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    Time- and cell-specific activation of BMP signaling restrains chondrocyte hypertrophy
    1
    1. scibot 19 Aug 2024
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      DOI: 10.1016/j.isci.2024.110537

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    sciencedirect.com/science/article/pii/S2589004224017620
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    Glycogen Synthase Kinase 3 inhibition controls Mycobacterium tuberculosis Infection
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      DOI: 10.1016/j.isci.2024.110555

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    sciencedirect.com/science/article/pii/S2589004224017802
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    A High-Throughput Screening Identifies MCM Chromatin loading Inhibitors Targeting Cells with increased Replication Origins
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      DOI: 10.1016/j.isci.2024.110567

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    sciencedirect.com/science/article/pii/S2589004224017929
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    The lateral habenula integrates age and experience to promote social transitions in developing rats
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      DOI: 10.1016/j.celrep.2024.114556

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    sciencedirect.com/science/article/pii/S2211124724008854
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-2 is essential for proliferation and self-renewal of nucleophosmin-mutated acute myeloid leukemia
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      DOI: 10.1126/sciadv.adj3145

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    ncbi.nlm.nih.gov/pmc/articles/PMC11296348/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metabolic disruption impairs ribosomal protein levels, resulting in enhanced aminoglycoside tolerance
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      DOI: 10.7554/eLife.94903

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    ncbi.nlm.nih.gov/pmc/articles/PMC11296704/
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    Protocol to establish a demyelinated animal model to study hippocampal neurogenesis and cognitive function in adult rodents
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      DOI: 10.1016/j.xpro.2024.103242

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    sciencedirect.com/science/article/pii/S2666166724004076
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    Tissue-specific sex-dependent difference in the metabolism of fatty acid esters of hydroxy fatty acids
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      DOI: 10.1016/j.bbalip.2024.159543

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    sciencedirect.com/science/article/pii/S1388198124000933
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    Tumor necrosis factor alpha induces NOX2-dependent reactive oxygen species production in hypothalamic paraventricular nucleus neurons following angiotensin II infusion
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      DOI: 10.1016/j.neuint.2024.105825

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    sciencedirect.com/science/article/pii/S0197018624001529
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    Redox heterogeneity in mouse embryonic stem cells individualizes cell fate decisions
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      DOI: 10.1016/j.devcel.2024.07.008

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    sciencedirect.com/science/article/pii/S1534580724004453
  33. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Arachidonic acid metabolism regulates the development of retinopathy of prematurity among preterm infants
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      DOI: 10.1111/jnc.16190

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    onlinelibrary.wiley.com/doi/10.1111/jnc.16190
  34. onlinelibrary.wiley.com onlinelibrary.wiley.com
    A common variant in the iron regulatory gene (Hfe) alters the metabolic and transcriptional landscape in brain regions vulnerable to neurodegeneration
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      DOI: 10.1111/jnc.16171

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  35. www.cell.com www.cell.com
    Calcineurin is an adaptor required for assembly of the TCR signaling complex
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      DOI: 10.1016/j.celrep.2024.114568

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    cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
  36. www.cell.com www.cell.com
    The amalgam of naive CD4+ T cell transcriptional states is reconfigured by helminth infection to dampen the amplitude of the immune response
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      DOI: 10.1016/j.immuni.2024.07.006

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    cell.com/immunity/fulltext/S1074-7613(24)00355-8
  37. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.16508

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.16508
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting heme degradation pathway augments prostate cancer cell sensitivity to docetaxel-induced apoptosis and attenuates migration
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      DOI: 10.3389/fonc.2024.1431362

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    ncbi.nlm.nih.gov/pmc/articles/PMC11291216/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The BET PROTAC inhibitor GNE-987 displays anti-tumor effects by targeting super-enhancers regulated gene in osteosarcoma
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      DOI: 10.1186/s12885-024-12691-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292958/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Exploiting Metabolic Defects in Glioma with Nanoparticle-Encapsulated NAMPT Inhibitors
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      DOI: 10.1158/1535-7163.MCT-24-0012

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    ncbi.nlm.nih.gov/pmc/articles/PMC11292319/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell discovery of m6A RNA modifications in the hippocampus
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      DOI: 10.1101/gr.278424.123

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    ncbi.nlm.nih.gov/pmc/articles/PMC11293556/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Personalized ctDNA for Monitoring Disease Status in Head and Neck Squamous Cell Carcinoma
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    Comprehensive Target Engagement by the EZH2 Inhibitor Tulmimetostat Allows for Targeting of ARID1A Mutant Cancers
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    Immune modulation of innate and adaptive responses restores immune surveillance and establishes anti-tumor immunological memory
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    Wild-type MeCp2 expression coincides with age-dependent sensory phenotypes in a female mouse model for Rett syndrome
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    Elastin-like polypeptide delivery of anti-inflammatory peptides to the brain following ischemic stroke
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    High-fat and high-sucrose diet-induced hypothalamic inflammation shows sex specific features in mice
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    Enhanced Effects of Intermittent Fasting by Magnetic Fields in Severe Diabetes
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    Co-occurrence of azorubine and bisphenol A in beverages increases the risk of developmental toxicity: A study in zebrafish model
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    Control of mitophagy initiation and progression by the TBK1 adaptors NAP1 and SINTBAD
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  57. www.cell.com www.cell.com
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    Enhanced human periodontal ligament stem cell viability and osteogenic differentiation on two implant materials: An experimental in vitro study
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    3D-informed targeting of the Trop-2 signal-activation site drives selective cancer vulnerability
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    Genetic basis for an evolutionary shift from ancestral preaxial to postaxial limb polarity in non-urodele vertebrates
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    Reduction in Hindquarter Vascular Resistance Supports 5-HT7 Receptor Mediated Hypotension
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    Different tonotopic regions of the lateral superior olive receive a similar combination of afferent inputs
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    Brain STAT5 modulates long-term metabolic and epigenetic changes induced by pregnancy and lactation in female mice
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    A control region near the fibroblast growth factor 23 gene mediates response to phosphate, 1,25(OH)2D3 and LPS in vivo
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    Activation of Notch Signaling by Oocytes and Jag1 in Mouse Ovarian Granulosa Cells
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    Spermatogonial Type 3 Deiodinase Regulates Thyroid Hormone Target Genes in Developing Testicular Somatic Cells
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    Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice
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  71. www.bio-protocol.org www.bio-protocol.org
    Aldicarb-induced Paralysis Assay to Determine Defects in Synaptic Transmission in Caenorhabditis elegans —BIO-PROTOCOL
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  72. academic.oup.com academic.oup.com
    Deletion of the Thyroid Hormone–Activating Type 2 Deiodinase Rescues Cone Photoreceptor Degeneration but Not Deafness in Mice Lacking Type 3 Deiodinase
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  73. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Altered expression of IGF‐I system in neurons of the inflamed spinal cord during acute Experimental Autoimmune Encephalomyelitis
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    Hippocampal lipid differences in Alzheimer's disease: a human brain study using matrix‐assisted laser desorption/ionization‐imaging mass spectrometry
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  75. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Distinct migratory behaviors of striosome and matrix cells underlying the mosaic formation in the developing striatum
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  76. www.nature.com www.nature.com
    The molecular, temporal and region-specific requirements of the beta isoform of Calcium/Calmodulin-dependent protein kinase type 2 (CAMK2B) in mouse locomotion
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  77. www.nature.com www.nature.com
    GSG1L suppresses AMPA receptor-mediated synaptic transmission and uniquely modulates AMPA receptor kinetics in hippocampal neurons
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  78. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Novel role of cystic fibrosis transmembrane conductance regulator in maintaining adult mouse olfactory neuronal homeostasis
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  79. onlinelibrary.wiley.com onlinelibrary.wiley.com
    An optimized dosing regimen of cimaglermin (neuregulin 1β3, glial growth factor 2) enhances molecular markers of neuroplasticity and functional recovery after permanent ischemic stroke in rats
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    Fezf2 expression in layer 5 projection neurons of mature mouse motor cortex
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    Postsynaptic gephyrin clustering controls the development of adult‐born granule cells in the olfactory bulb
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    Serotonin and insulin‐like peptides modulate leucokinin‐producing neurons that affect feeding and water homeostasis in Drosophila
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    Deletion of the amyloid precursor‐like protein 1 (APLP1) enhances excitatory synaptic transmission, reduces network inhibition but does not impair synaptic plasticity in the mouse dentate gyrus
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    Synaptic localization of α5 GABA (A) receptors via gephyrin interaction regulates dendritic outgrowth and spine maturation
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    Postsynaptic P2X3‐containing receptors in gustatory nerve fibres mediate responses to all taste qualities in mice
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    Induction of early neural precursors and derivation of tripotent neural stem cells from human pluripotent stem cells under xeno‐free conditions
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    Oral Release Kinetics, Biodistribution, and Excretion of Dopants from Barium-Containing Bioactive Glass in Rats
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    Efficacy and Safety of Hydrogen Therapy in Patients with Early-Stage Interstitial Lung Disease: A Single-Center, Randomized, Parallel-Group Controlled Trial
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    ACh-induced hyperpolarization and decreased resistance in mammalian type II vestibular hair cells. | Journal of Neurophysiology
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  97. bio-protocol.org bio-protocol.org
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    A Comparative Analysis of the Physiological Properties of Neurons in the Anterolateral Bed Nucleus of the Stria Terminalis in the Mus musculus, Rattus norvegicus, and Macaca mulatta
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    Individual sympathetic postganglionic neurons coinnervate myenteric ganglia and smooth muscle layers in the gastrointestinal tract of the rat
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    A postnatal peak in microglial development in the mouse hippocampus is correlated with heightened sensitivity to seizure triggers
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    Synapsin knockdown is associated with decreased neurite outgrowth, functional synaptogenesis impairment, and fast high‐frequency neurotransmitter release
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    Erythropoietin produced by genetic‐modified NIH/3T3 fibroblasts enhances the survival of degenerating neurons
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    Connexin50 couples axon terminals of mouse horizontal cells by homotypic gap junctions
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    Characterization and changes in neurotrophin receptor p75‐expressing motor neurons in SOD1G93AG1H mice
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    Quantitative profiling of neurotransmitter abnormalities in brain, cerebrospinal fluid, and serum of experimental diabetic encephalopathy male rat
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    Clinical, electrophysiological, and biochemical markers of peripheral and central nervous system disease in canine globoid cell leukodystrophy (Krabbe's disease)
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    Metabolic profiling reveals biochemical pathways and potential biomarkers associated with the pathogenesis of Krabbe disease
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    Lithium improves cell viability in psychosine‐treated MO3.13 human oligodendrocyte cell line via autophagy activation
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    Expression of homeobox genes in the mouse olfactory epithelium
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    The carbocyanine dye DiD labels in vitro and in vivo neural stem cells of the subventricular zone as well as myelinated structures following in vivo injection in the lateral ventricle
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  114. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Topographic specializations in the retinal ganglion cell layer correlate with lateralized visual behavior, ecology, and evolution in cockatoos
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  115. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Effects of progesterone on hyperoxia‐induced damage in mouse C8‐D1A astrocytes
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    Topographic specializations in the retinal ganglion cell layer of Australian passerines
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    Neomycin damage and regeneration of hair cells in both mechanoreceptor and electroreceptor lateral line organs of the larval Siberian sturgeon (Acipenser baerii)
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    Rescue of deficient amygdala tonic γ‐aminobutyric acidergic currents in the Fmr–/y mouse model of fragile X syndrome by a novel γ‐aminobutyric acid type A receptor‐positive allosteric modulator
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    Alterations in the subcellular distribution of NADPH oxidase p47phox in hypothalamic paraventricular neurons following slow‐pressor angiotensin II hypertension in female mice with accelerated ovarian failure
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    Modulation of extracellular signal‐related kinase, cyclin D1, glial fibrillary acidic protein, and vimentin expression in estradiol‐pretreated astrocyte cultures treated with competence and progression growth factors
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    Association of N‐cadherin levels and downstream effectors of Rho GTPases with dendritic spine loss induced by chronic stress in rat hippocampal neurons
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    Colocalization of allatotropin and tachykinin‐related peptides with classical transmitters in physiologically distinct subtypes of olfactory local interneurons in the cockroach (Periplaneta americana)
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    Variations in retinal photoreceptor topography and the organization of the rod‐free zone reflect behavioral diversity in Australian passerines
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    DEP domain‐containing mTOR‐interacting protein in the rat brain: Distribution of expression and potential implication
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    E2F1-associated purine synthesis pathway is a major component of the MET-DNA damage response network
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    Non-classical monocytes scavenge the growth factor CSF1 from endothelial cells in the peripheral vascular tree to ensure survival and homeostasis
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    The SRC family kinase inhibitor NXP900 demonstrates potent anti-tumor activity in squamous cell carcinomas
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    Many human pharmaceuticals are weak inhibitors of the cytochrome P450 system in rainbow trout (Oncorhynchus mykiss) liver S9 fractions
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cerebellar nuclei cells produce distinct pathogenic spike signatures in mouse models of ataxia, dystonia, and tremor
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    A Comprehensive Protocol for Efficient Differentiation of Human NPCs into Electrically Competent Neurons
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    Neohesperidin alleviates the inhibitory effect of bisphenol A on the myogenic differentiation of umbilical cord mesenchymal stem cells via the IGF1R/AKT1/RHOA signaling pathway
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    High‐fidelity CRISPR/Cas12a dual‐crRNA screening reveals novel synergistic interactions in hepatocellular carcinoma
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    The chemokine Cxcl14 regulates interneuron differentiation in layer I of the somatosensory cortex
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    Approaches to scarless burn wound healing: application of 3D printed skin substitutes with dual properties of anti-infection and balancing wound hydration levels
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  152. www.biorxiv.org www.biorxiv.org
    Motor Cortical Neuronal Hyperexcitability Associated with α-Synuclein Aggregation
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    Combined inhibition of EZH2 and CDK4/6 perturbs endoplasmic reticulum-mitochondrial homeostasis and increases antitumor activity against glioblastoma
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    Microglia rescue neurons from aggregate-induced neuronal dysfunction and death through tunneling nanotubes
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    Movement-related increases in subthalamic activity optimize locomotion
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    NK Cytotoxicity Mediated by NK-92 Cell Lines Expressing Combinations of Two Allelic Variants for FCGR3
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  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Adult-onset deletion of ATP13A2 in mice induces progressive nigrostriatal pathway dopaminergic degeneration and lysosomal abnormalities
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Impact of LAG-3/FGL1 pathway on immune evasive contexture and clinical outcomes in advanced urothelial carcinoma
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  159. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
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    N-Myristoyltransferase Inhibition causes Mitochondrial Iron Overload and Parthanatos in TIM17A-dependent Aggressive Lung Carcinoma
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  161. 52.53.155.43 52.53.155.43
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  162. 52.53.155.43 52.53.155.43
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    Pandemic-associated pernio harbors footprints of an abortive SARS-CoV-2 infection
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    Integrated transcriptomics of human blood vessels defines a spatially controlled niche for early mesenchymal progenitor cells
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    Visual feedback neurons fine-tune Drosophila male courtship via GABA-mediated inhibition
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    Systematic analysis of RhoGEF/GAP localizations uncovers regulators of mechanosensing and junction formation during epithelial cell division
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  170. 52.53.155.43 52.53.155.43
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    Substrate Stiffness Alters Layer Architecture and Biophysics of Human Induced Pluripotent Stem Cells to Modulate their Differentiation Potential
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    Ketamine ameliorates post-traumatic social avoidance by erasing the traumatic memory encoded in VTA-innervated BLA engram cells
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    The histone demethylase KDM5 is required for synaptic structure and function at the Drosophila neuromuscular junction
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    Molecular Logic of Synaptic Diversity Between Drosophila Tonic and Phasic Motoneurons
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    PAI-1 uncouples integrin-β1 from restrain by membrane-bound β-catenin to promote collagen fibril remodeling in obesity-related neoplasms
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    Parallel synaptic acetylcholine signals facilitate large monopolar cell repolarization and modulate visual behavior in Drosophila
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    Mitochondrial transfer between BMSCs and Müller promotes mitochondrial fusion and suppresses gliosis in degenerative retina
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    IRF4 requires ARID1A to establish plasma cell identity in multiple myeloma
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    Ergosterol and its metabolites as agonists of Liver X receptor and their anticancer potential in colorectal cancer
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