3,016 Matching Annotations
  1. Nov 2024
  2. www.sciencedirect.com www.sciencedirect.com
    A PROTAC degrader suppresses oncogenic functions of PTK6 inducing apoptosis of breast cancer cells
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    sciencedirect.com/science/article/pii/S2451945624004434
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    A maternal high-fat diet predisposes to infant lung disease via increased neutrophil-mediated IL-6 trans-signaling
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    sciencedirect.com/science/article/pii/S2211124724013251
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    Multimodal targeting chimeras enable integrated immunotherapy leveraging tumor-immune microenvironment
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    sciencedirect.com/science/article/pii/S009286742401198X
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    Bach2 repression of CD36 regulates lipid-metabolism-linked effector functions in follicular B cells
    8
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    sciencedirect.com/science/article/pii/S2211124724012294
  6. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    High TNF and NF-κB Pathway Dependency Are Associated with AZD5582 Sensitivity in OSCC via CASP8-Dependent Apoptosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11551840/
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    CRISPRi/a screens in human iPSC-cardiomyocytes identify glycolytic activation as a druggable target for doxorubicin-induced cardiotoxicity
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    sciencedirect.com/science/article/pii/S1934590924003692
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systemic inflammation accelerates neurodegeneration in a rat model of Parkinson’s disease overexpressing human alpha synuclein
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    pmc.ncbi.nlm.nih.gov/articles/PMC11538257/
  9. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Age-Associated Contraction of Tumor-Specific T Cells Impairs Antitumor Immunity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532741/
  10. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Targeting Catechol-O-Methyltransferase Induces Mitochondrial Dysfunction and Enhances the Efficacy of Radiotherapy in Glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC11532787/
  11. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Neurons enhance blood–brain barrier function via upregulating claudin-5 and VE-cadherin expression due to glial cell line-derived neurotrophic factor secretion
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    pmc.ncbi.nlm.nih.gov/articles/PMC11524583/
  12. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Human papillomavirus infection affects the immune microenvironment and antigen presentation in penile cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11527599/
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Assessing the metastatic potential of circulating tumor cells using an organ-on-chip model
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    pmc.ncbi.nlm.nih.gov/articles/PMC11493642/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ablation of PC1/3 in POMC-expressing Tissues but not in Immune Cells Induces Sepsis Hypersensitivity
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    pmc.ncbi.nlm.nih.gov/articles/PMC11492489/
  15. 52.53.155.43 52.53.155.43
    crc-24-0310-html.html
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    52.53.155.43/449361f05b483e756cda1d8fd2c4f1dacb3af208/crc-24-0310-html.html
  16. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Acute Lymphoblastic Leukemia with Myeloid Mutations Is a High-Risk Disease Associated with Clonal Hematopoiesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC11061587/
  17. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    4’-Ethynyl-2’-Deoxycytidine (EdC) Preferentially Targets Lymphoma and Leukemia Subtypes by Inducing Replicative Stress
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    pmc.ncbi.nlm.nih.gov/articles/PMC11286238/
  18. www.biorxiv.org www.biorxiv.org
    TXNIP mediates LAT1/SLC7A5 endocytosis to reduce amino acid uptake in cells entering quiescence
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    biorxiv.org/lookup/doi/10.1101/2024.10.29.620655
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Succinylation of a KEAP1 sensor lysine promotes NRF2 activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC10592117/
  20. Oct 2024
  21. link.springer.com link.springer.com
    Antitumor effects of intracranial injection of B7-H3-targeted Car-T and Car-Nk cells in a patient-derived glioblastoma xenograft model
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    link.springer.com/article/10.1007/s00262-024-03808-0
  22. aacrjournals.org aacrjournals.org
    NK Receptor Signaling Lowers TCR Activation Threshold, Enhancing Selective Recognition of Cancer Cells by TAA-Specific CTLs
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    aacrjournals.org/cancerimmunolres/article/12/10/1421/748722/NK-Receptor-Signaling-Lowers-TCR-Activation
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxyproline metabolism enhances IFN-γ-induced PD-L1 expression and inhibits autophagic flux
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11426993/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quiescence and aging of melanocyte stem cells and a novel association with PD-L1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11440800/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CCL28 modulates neutrophil responses during infection with mucosal pathogens
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    ncbi.nlm.nih.gov/pmc/articles/PMC11444682/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Redirecting B7-H3.CAR T cells to Chemokines Expressed in Osteosarcoma Enhances Homing and Antitumor Activity in Preclinical Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443211/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Autofluorescent Cancer Stem Cells: Potential Biomarker to Predict Recurrence in Resected Colorectal Tumors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11445700/
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Prime-Boost Vaccination Approach Induces Lung Resident Memory CD8+ T Cells Derived from Central Memory T Cells That Prevent Tumor Lung Metastasis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443216/
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxia-Induced Long Noncoding RNA HIF1A-AS2 Regulates Stability of MHC Class I Protein in Head and Neck Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11443317/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NAPRT silencing in FH-deficient renal cell carcinoma confers therapeutic vulnerabilities via NAD+ depletion
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    ncbi.nlm.nih.gov/pmc/articles/PMC11445649/
  31. www.biorxiv.org www.biorxiv.org
    MITF Targets in Gastrointestinal Stromal Tumors: Implications in Autophagy and Extracellular Vesicle Secretion
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    biorxiv.org/content/10.1101/2024.09.10.612253v1
  32. faseb.onlinelibrary.wiley.com faseb.onlinelibrary.wiley.com
    Spatially restricted ecto-5′-nucleotidase expression promotes the growth of uterine leiomyomas by modulating Akt activity
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    faseb.onlinelibrary.wiley.com/doi/10.1096/fj.202401432R
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The androgen receptor in mesenchymal progenitors regulates skeletal muscle mass via Igf1 expression in male mice
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    ncbi.nlm.nih.gov/pmc/articles/PMC11441553/
  34. aacrjournals.org aacrjournals.org
    YAP-Mediated Repression of HRK Regulates Tumor Growth, Therapy Response, and Survival Under Tumor Environmental Stress in Neuroblastoma
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    aacrjournals.org/cancerres/article/80/21/4741/645935/YAP-Mediated-Repression-of-HRK-Regulates-Tumor
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Breadth of Fc-mediated effector function correlates with clinical immunity following human malaria challenge
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    ncbi.nlm.nih.gov/pmc/articles/PMC7616646/
  36. www.sciencedirect.com www.sciencedirect.com
    Protocol for engineering binding domains to recognize ligand-bound receptors by using yeast surface display
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    sciencedirect.com/science/article/pii/S2666166724005045
  37. Sep 2024
  38. www.sciencedirect.com www.sciencedirect.com
    A PD-1-targeted, receptor-masked IL-2 immunocytokine that engages IL-2Rα strengthens T cell-mediated anti-tumor therapies
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    sciencedirect.com/science/article/pii/S2666379124004774
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    Discovery and characterization of a pan-betacoronavirus S2-binding antibody
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    sciencedirect.com/science/article/pii/S0969212624003691
  40. physoc.onlinelibrary.wiley.com physoc.onlinelibrary.wiley.com
    Inducible deletion of endothelial cell Efnb2 delays capillary regeneration and attenuates myofibre reinnervation following myotoxin injury in mice
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    physoc.onlinelibrary.wiley.com/doi/10.1113/JP285402
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic Efficacy of IL7/CCL19-Expressing CAR-T Cells in Intractable Solid Tumor Models of Glioblastoma and Pancreatic Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11423281/
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    A living organoid biobank of patients with Crohn’s disease reveals molecular subtypes for personalized therapeutics
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    sciencedirect.com/science/article/pii/S2666379124004786
  43. www.cell.com www.cell.com
    Calcineurin is an adaptor required for assembly of the TCR signaling complex
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    cell.com/cell-reports/fulltext/S2211-1247(24)00897-0
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    Protocol for monitoring phagocytosis of cancer cells by TAM-like macrophages using imaging cytometry
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    sciencedirect.com/science/article/pii/S2666166724004854
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    Protocol for assessing murine cell doublet engagement and subsequent effects using flow cytometry and imaging flow cytometry
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    sciencedirect.com/science/article/pii/S2666166724003174
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    CXCR4 orchestrates the TOX-programmed exhausted phenotype of CD8+ T cells via JAK2/STAT3 pathway
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    sciencedirect.com/science/article/pii/S2666979X24002702
  47. elifesciences.org elifesciences.org
    Mutant mice lacking alternatively spliced p53 isoforms unveil Ackr4 as a male-specific prognostic factor in Myc-driven B-cell lymphomas
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    elifesciences.org/articles/92774
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    CD38 symmetric dimethyl site R58 promotes malignant tumor cell immune escape by regulating the cAMP-GSK3β-PD-L1 Axis
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    sciencedirect.com/science/article/pii/S2405844024139898
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    Tumour-associated mesenchymal stromal cells modulate macrophage phagocytosis in stromal-rich colorectal cancer via PD-1 signalling.
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    sciencedirect.com/science/article/pii/S2589004224019266
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    Group X phospholipase A2 links colonic lipid homeostasis to systemic metabolism via host-microbiota interaction
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    sciencedirect.com/science/article/pii/S2211124724011033
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    NOX1-dependent redox signaling potentiates colonic stem cell proliferation to adapt to the intestinal microbiota by linking EGFR and TLR activation
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    sciencedirect.com/science/article/pii/S2211124721002631
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    β-Glucan Induces Protective Trained Immunity against Mycobacterium tuberculosis Infection: A Key Role for IL-1
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    sciencedirect.com/science/article/pii/S2211124720305878
  53. www.sciencedirect.com www.sciencedirect.com
    A Model of Differential Mammary Growth Initiation by Stat3 and Asymmetric Integrin-α6 Inheritance
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    sciencedirect.com/science/article/pii/S2211124720302539
  54. www.sciencedirect.com www.sciencedirect.com
    Generation of Human PSC-Derived Kidney Organoids with Patterned Nephron Segments and a De Novo Vascular Network
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    sciencedirect.com/science/article/pii/S1934590919302735
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL36G-producing neutrophil-like monocytes promote cachexia in cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11393454/
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    Rewired glutamate metabolism diminishes cytostatic action of L-asparaginase
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    sciencedirect.com/science/article/pii/S0304383524006372
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    Validation of a PD-1/CD28 chimeric switch receptor to augment CAR-T function in dogs with spontaneous B cell lymphoma
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    sciencedirect.com/science/article/pii/S2589004224020881
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    Tumor-reactive T cell clonotype dynamics underlying clinical response to TIL therapy in melanoma
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    sciencedirect.com/science/article/pii/S1074761324004138
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    Dynamic allostery drives autocrine and paracrine TGF-β signaling
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    sciencedirect.com/science/article/pii/S0092867424009656
  60. www.sciencedirect.com www.sciencedirect.com
    MG53 suppresses tumor growth via transcriptional inhibition of KIF11 in pancreatic cancer
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    sciencedirect.com/science/article/pii/S1936523324002456
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GRP94 Promotes Anoikis Resistance and Peritoneal Metastasis through YAP/TEAD1 pathway in Gastric Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11381759/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Immune isolation-enabled nanoencapsulation of donor T cells: a promising strategy for mitigating GVHD and treating AML in preclinical models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11381671/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Pretargeted Radioimmunotherapy with the Novel Anti-oxMIF/HSG Bispecific Antibody ON105 Results in Significant Tumor Regression in Murine Models of Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372362/
  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RUVBL1/2 Blockade Targets YTHDF1 Activity to Suppress m6A-Dependent Oncogenic Translation and Colorectal Tumorigenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11372367/
  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Recombinant origin and interspecies transmission of a HERV-K(HML-2)-related primate retrovirus with a novel RNA transport element
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    ncbi.nlm.nih.gov/pmc/articles/PMC11379458/
  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized in vivo multispectral bioluminescent imaging of tumor biology using engineered BRET reporters
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    ncbi.nlm.nih.gov/pmc/articles/PMC11381837/
  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Eslicarbazepine induces apoptosis and cell cycle arrest in C6 glioma cells in vitro and suppresses tumor growth in an intracranial rat model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11373099/
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Siglec‐7 and Siglec‐9 expression in primary triple negative and oestrogen receptor positive breast cancer and in vitro signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11378723/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activation of Cell-Intrinsic Signaling in CAR-T Cells via a Chimeric IL7R Domain
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    ncbi.nlm.nih.gov/pmc/articles/PMC11382189/
  70. www.sciencedirect.com www.sciencedirect.com
    T cell responses to repeated SARS-CoV-2 vaccination and breakthrough infections in patients on TNF inhibitor treatment: a prospective cohort study
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    sciencedirect.com/science/article/pii/S2352396424003530
  71. www.sciencedirect.com www.sciencedirect.com
    Unraveling the phenotypic states of human innate-like T cells: Comparative insights with conventional T cells and mouse models
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    sciencedirect.com/science/article/pii/S2211124724010568
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IL-2 and TCR stimulation induce expression and secretion of IL-32β by human T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11357969/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Inhibition of Aberrantly Overexpressed Polo-like Kinase 4 Is a Potential Effective Treatment for DNA Damage Repair–Deficient Uterine Leiomyosarcoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369621/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Phase II Study of Potentiation of Pembrolizumab with Binimetinib and Bevacizumab in Refractory Microsatellite-Stable Colorectal Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369619/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PlexinB1 Inactivation Reprograms Immune Cells in the Tumor Microenvironment, Inhibiting Breast Cancer Growth and Metastatic Dissemination
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    ncbi.nlm.nih.gov/pmc/articles/PMC11369622/
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    Inhibitory co-receptor Lag3 supports Foxp3+ regulatory T cell function by restraining Myc-dependent metabolic programming
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    sciencedirect.com/science/article/pii/S1074761324004072
  77. www.sciencedirect.com www.sciencedirect.com
    The transcription regulator ID3 maintains tumor-specific memory CD8+ T cells in draining lymph nodes during tumorigenesis
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    sciencedirect.com/science/article/pii/S2211124724010416
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    Osteocalcin-expressing neutrophils from skull bone marrow exert immunosuppressive and neuroprotective effects after TBI
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    sciencedirect.com/science/article/pii/S2211124724010210
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    Autoantigen-specific CD4+ T cells acquire an exhausted phenotype and persist in human antigen-specific autoimmune diseases
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    sciencedirect.com/science/article/pii/S1074761324004047
  80. Aug 2024
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Potentiating Salvage Radiotherapy in Radiorecurrent Prostate Cancer Through Anti-CTLA4 Therapy: Implications from a Syngeneic Model
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    ncbi.nlm.nih.gov/pmc/articles/PMC11352774/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Lactate Receptor GPR81 is a Mechanism of Leukemia-Associated Macrophage Polarization in the Bone Marrow Microenvironment
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    ncbi.nlm.nih.gov/pmc/articles/PMC11343108/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of Forkhead Box P3 in Interferon γ-mediated PD-L1 Expression and Bladder Cancer Epithelial-to-Mesenchymal Transition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11345674/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ILC2-derived LIF licences progress from tissue to systemic immunity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11338826/
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    Immune suppression by human thymus-derived effector Tregs relies on glucose/lactate-fueled fatty acid synthesis
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    sciencedirect.com/science/article/pii/S2211124724010325
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    Mitochondrial serine catabolism safeguards maintenance of the hematopoietic stem cell pool in homeostasis and injury
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    sciencedirect.com/science/article/pii/S1934590924002856
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumoral Interferon Beta Induces an Immune-Stimulatory Phenotype in Tumor-Associated Macrophages in Melanoma Brain Metastases
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    ZNF143 is a transcriptional regulator of nuclear-encoded mitochondrial genes that acts independently of looping and CTCF
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