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  1. Sep 2020
  2. www.sciencedirect.com www.sciencedirect.com
    Route of Vaccine Administration Alters Antigen Trafficking but Not Innate or Adaptive Immunity
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      DOI: 10.1016/j.celrep.2020.02.111

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    sciencedirect.com/science/article/pii/S2211124720302928
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    Signaling diversity enabled by Rap1-regulated plasma membrane ERK with distinct temporal dynamics
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      DOI: 10.7554/eLife.57410

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    ncbi.nlm.nih.gov/pmc/articles/PMC7289600/
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    Building the vertebrate codex using the gene breaking protein trap library
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      DOI: 10.7554/eLife.54572

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    microRNA‐9‐5p alleviates blood‐brain barrier damage and neuroinflammation after traumatic brain injury
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      DOI: 10.1111/jnc.14963

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    Dorsal Hippocampal Actin Polymerization is Necessary for Activation of G-protein-Coupled Estrogen Receptor (GPER) to Increase CA1 Dendritic Spine Density and Enhance Memory Consolidation
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      DOI: 10.1523/JNEUROSCI.2687-18.2019

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    Social Behavioral Deficits with Loss of Neurofibromin Emerge from Peripheral Chemosensory Neuron Dysfunction
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    Small Molecule Inhibition of GSK-3 Specifically Inhibits the Transcription of Inhibitory Co-receptor LAG-3 for Enhanced Anti-tumor Immunity
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    sciencedirect.com/science/article/pii/S2211124720301017
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      DOI: 10.1111/bph.14849

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    Presynaptic development is controlled by the core active zone proteins CAST/ELKS
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      DOI: 10.1113/JP279736

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    Acute Treatment With Gleevec Does Not Promote Early Vascular Recovery Following Intracerebral Hemorrhage in Adult Male Rats
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      DOI: 10.3389/fnins.2020.00046

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    A Requirement for Argonaute 4 in Mammalian Antiviral Defense
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      DOI: 10.1016/j.celrep.2020.01.021

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    sciencedirect.com/science/article/pii/S2211124720300309
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    Microglia TREM2R47H Alzheimer-linked variant enhances excitatory transmission and reduces LTP via increased TNF-α levels
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      DOI: 10.7554/eLife.57513

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    Direct Comparison of Mononucleated and Binucleated Cardiomyocytes Reveals Molecular Mechanisms Underlying Distinct Proliferative Competencies
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      DOI: 10.1016/j.celrep.2020.02.034

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    TUBB4A mutations result in both glial and neuronal degeneration in an H-ABC leukodystrophy mouse model
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      DOI: 10.7554/eLife.52986

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    ncbi.nlm.nih.gov/pmc/articles/PMC7255805/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A high-throughput small molecule screen identifies farrerol as a potentiator of CRISPR/Cas9-mediated genome editing
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      DOI: 10.7554/eLife.56008

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      DOI: 10.1111/bph.15083

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  18. elifesciences.org elifesciences.org
    Yap1 promotes sprouting and proliferation of lymphatic progenitors downstream of Vegfc in the zebrafish trunk
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      DOI: 10.7554/eLife.42881

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    elifesciences.org/articles/42881
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of CAR-T cell therapy for B-ALL using a point-of-care approach
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      DOI: 10.1080/2162402X.2020.1752592

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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Androgen receptor antagonism accelerates disease onset in the SOD1G93A mouse model of amyotrophic lateral sclerosis
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      DOI: 10.1111/bph.14657

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  21. www.nature.com www.nature.com
    Zinc-finger antiviral protein acts as a tumor suppressor in colorectal cancer
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      DOI: 10.1038/s41388-020-01416-7

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    nature.com/articles/s41388-020-01416-7
  22. www.nature.com www.nature.com
    Spatial proteomics revealed a CX 3 CL1-dependent crosstalk between the urothelium and relocated macrophages through IL-6 during an acute bacterial infection in the urinary bladder
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      DOI: 10.1038/s41385-020-0269-7

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  23. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
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      DOI: 10.1111/bph.14828

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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell-type-specific regulation of neuronal intrinsic excitability by macroautophagy
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      DOI: 10.7554/eLife.50843

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    ncbi.nlm.nih.gov/pmc/articles/PMC6984822/
  25. www.sciencedirect.com www.sciencedirect.com
    Ultrastructural Correlates of Presynaptic Functional Heterogeneity in Hippocampal Synapses
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      DOI: 10.1016/j.celrep.2020.02.083

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    sciencedirect.com/science/article/pii/S2211124720302576
  26. elifesciences.org elifesciences.org
    How to measure and evaluate binding affinities
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      DOI: 10.7554/eLife.57264

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  27. insight.jci.org insight.jci.org
    Renal protective effects of empagliflozin via inhibition of EMT and aberrant glycolysis in proximal tubules
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      DOI: 10.1172/jci.insight.129034

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  28. www.sciencedirect.com www.sciencedirect.com
    Pathogenic Tau Causes a Toxic Depletion of Nuclear Calcium
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      DOI: 10.1016/j.celrep.2020.107900

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    Impaired tricarboxylic acid cycle flux and mitochondrial aerobic respiration during isoproterenol induced myocardial ischemia is rescued by bilobalide
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      DOI: 10.1016/j.jpha.2020.08.008

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    sciencedirect.com/science/article/pii/S2095177920310492
  30. elifesciences.org elifesciences.org
    Inhibition of striatonigral autophagy as a link between cannabinoid intoxication and impairment of motor coordination
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      DOI: 10.7554/eLife.56811

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  31. elifesciences.org elifesciences.org
    Nicotinamide mononucleotide adenylyltransferase uses its NAD+ substrate-binding site to chaperone phosphorylated Tau
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      DOI: 10.7554/eLife.51859

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  32. www.frontiersin.org www.frontiersin.org
    Naïve, Regulatory, Activated, and Memory Immune Cells Co-exist in PVATs That Are Comparable in Density to Non-PVAT Fats in Health
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      DOI: 10.3389/fphys.2020.00058

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  33. www.sciencedirect.com www.sciencedirect.com
    Population Density Modulates the Duration of Reproduction of C. elegans
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      DOI: 10.1016/j.cub.2020.04.056

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    sciencedirect.com/science/article/pii/S0960982220305728
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of scavenger receptor B1 as the airway microfold cell receptor for Mycobacterium tuberculosis
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      DOI: 10.7554/eLife.52551

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  35. www.sciencedirect.com www.sciencedirect.com
    Visualization of T Cell Migration in the Spleen Reveals a Network of Perivascular Pathways that Guide Entry into T Zones
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      DOI: 10.1016/j.immuni.2020.03.010

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  36. www.cell.com www.cell.com
    The Amount of BCL6 in B Cells Shortly after Antigen Engagement Determines Their Representation in Subsequent Germinal Centers
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      DOI: 10.1016/j.celrep.2020.01.009

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    cell.com/cell-reports/abstract/S2211-1247(20)30018-8
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Approaching boiling point stability of an alcohol dehydrogenase through computationally-guided enzyme engineering
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      DOI: 10.7554/eLife.54639

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    ncbi.nlm.nih.gov/pmc/articles/PMC7164962/
  38. elifesciences.org elifesciences.org
    Homeostatic and tumourigenic activity of SOX2+ pituitary stem cells is controlled by the LATS/YAP/TAZ cascade
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      DOI: 10.7554/eLife.43996

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  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rapamycin rejuvenates oral health in aging mice
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      DOI: 10.7554/eLife.54318

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    ncbi.nlm.nih.gov/pmc/articles/PMC7220376/
  40. academic.oup.com academic.oup.com
    MEIOK21: a new component of meiotic recombination bridges required for spermatogenesis
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      DOI: 10.1093/nar/gkaa406

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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkaa406/5848248
  41. www.sciencedirect.com www.sciencedirect.com
    Distinct Mechanisms of Over-Representation of Landmarks and Rewards in the Hippocampus
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      DOI: 10.1016/j.celrep.2020.107864

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    sciencedirect.com/science/article/pii/S2211124720308457
  42. www.sciencedirect.com www.sciencedirect.com
    Chronic Viral Infection Promotes Efficient Germinal Center B Cell Responses
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      DOI: 10.1016/j.celrep.2019.12.023

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    Phenotypic Screen with TSC-Deficient Neurons Reveals Heat-Shock Machinery as a Druggable Pathway for mTORC1 and Reduced Cilia
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    Targeted De Novo Centromere Formation in Drosophila Reveals Plasticity and Maintenance Potential of CENP-A Chromatin
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    The FTLD Risk Factor TMEM106B Regulates the Transport of Lysosomes at the Axon Initial Segment of Motoneurons
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    Radiation Triggers a Dynamic Sequence of Transient Microglial Alterations in Juvenile Brain
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    An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates
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    Dopaminergic Transmission Rapidly and Persistently Enhances Excitability of D1 Receptor-Expressing Striatal Projection Neurons
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    A Cluster of Autism-Associated Variants on X-Linked NLGN4X Functionally Resemble NLGN4Y
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    Noncoding microdeletion in mouse Hgf disrupts neural crest migration into the stria vascularis, reduces the endocochlear potential and suggests the neuropathology for human nonsyndromic deafness DFNB39
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    AMPK-Regulated Astrocytic Lactate Shuttle Plays a Non-Cell-Autonomous Role in Neuronal Survival
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    Postnatal Overnutrition Induces Changes in Synaptic Transmission to Leptin Receptor-Expressing Neurons in the Arcuate Nucleus of Female Mice
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    Piezo1/2 mediate mechanotransduction essential for bone formation through concerted activation of NFAT-YAP1-ß-catenin
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    Spatiotemporal Decline of BMP Signaling Activity in Neural Progenitors Mediates Fate Transition and Safeguards Neurogenesis
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    An alternatively spliced, non-signaling insulin receptor modulates insulin sensitivity via insulin peptide sequestration in C. elegans
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    p16 deficiency attenuates intervertebral disc degeneration by adjusting oxidative stress and nucleus pulposus cell cycle
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    CXCR4 Signaling Has a CXCL12-Independent Essential Role in Murine MLL-AF9-Driven Acute Myeloid Leukemia
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    Single-Cell RNA Sequencing Maps Endothelial Metabolic Plasticity in Pathological Angiogenesis
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    Deletion of hypoxia‐responsive microRNA‐210 results in a sex‐specific decrease in nephron number
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    An Epilepsy-Associated GRIN2A Rare Variant Disrupts CaMKIIα Phosphorylation of GluN2A and NMDA Receptor Trafficking
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    Zeb2 Is a Regulator of Astrogliosis and Functional Recovery after CNS Injury
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    Enteric Glia Modulate Macrophage Phenotype and Visceral Sensitivity following Inflammation
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    Nef-Mediated CD3-TCR Downmodulation Dampens Acute Inflammation and Promotes SIV Immune Evasion
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    Stxbp1/Munc18-1 haploinsufficiency impairs inhibition and mediates key neurological features of STXBP1 encephalopathy
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    Molecular pathway analysis towards understanding tissue vulnerability in spinocerebellar ataxia type 1
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    Direct Readout of Neural Stem Cell Transgenesis with an Integration-Coupled Gene Expression Switch
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    EGFR signaling causes morphine tolerance and mechanical sensitization in rats
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    Antagonism of peripheral opioid receptors by methylnaltrexone does not prevent morphine tolerance in rats
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    Enhanced Akt/GSK‐3β/CREB signaling mediates the anti‐inflammatory actions of mGluR5 positive allosteric modulators in microglia and following traumatic brain injury in male mice
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    Metabolic and non-metabolic liver zonation is established non-synchronously and requires sinusoidal Wnts
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    Renal medullary carcinomas depend upon SMARCB1 loss and are sensitive to proteasome inhibition
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    Palmitate‐TLR4 signaling regulates the histone demethylase, JMJD3, in macrophages and impairs diabetic wound healing
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    Cdk4 and Cdk6 Couple the Cell-Cycle Machinery to Cell Growth via mTORC1
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    Acute cerebellar knockdown of Sgce reproduces salient features of myoclonus-dystonia (DYT11) in mice
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    MiR-146a Ameliorates Hemoglobin-Induced Microglial Inflammatory Response via TLR4/IRAK1/TRAF6 Associated Pathways
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    Transplantation of induced neural stem cells (iNSCs) into chronically demyelinated corpus callosum ameliorates motor deficits
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    Apolipoprotein E regulates the maturation of injury-induced adult-born hippocampal neurons following traumatic brain injury
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    Genome-Wide Identification of Genes Involved in General Acid Stress and Fluoride Toxicity in Saccharomyces cerevisiae
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    Phagocytic glia are obligatory intermediates in transmission of mutant huntingtin aggregates across neuronal synapses
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    Gene-Specific Linear Trends Constrain Transcriptional Variability of the Toll-like Receptor Signaling
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  139. cancerres.aacrjournals.org cancerres.aacrjournals.org
    Suppression of ABCE1-mediated mRNA translation limits N-MYC-driven cancer progression
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      DOI: 10.1158/0008-5472.CAN-19-3914

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    RGS6 Mediates Effects of Voluntary Running on Adult Hippocampal Neurogenesis
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    Anandamide Signalling Augmentation Rescues Amygdala Synaptic Function and Comorbid Emotional Alterations in a Model of Epilepsy
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      DOI: 10.1523/JNEUROSCI.0068-20.2020

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    Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner
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    UBP12 and UBP13 negatively regulate the activity of the ubiquitin-dependent peptidases DA1, DAR1 and DAR2
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    Presynaptic Active Zone Plasticity Encodes Sleep Need in Drosophila
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    Early life adversity decreases pre-adolescent fear expression by accelerating amygdala PV cell development
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    Marginal Zone Formation Requires ACKR3 Expression on B Cells
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    Physical Activity During Pregnancy Is Associated with Increased Placental FATP4 Protein Expression
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    Intersectin-Mediated Clearance of SNARE Complexes Is Required for Fast Neurotransmission
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    Exosomes derived from microglia exposed to elevated pressure amplify the neuroinflammatory response in retinal cells
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    Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model
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    Central nervous system‐infiltrated immune cells induce calcium increase in astrocytes via astroglial purinergic signaling
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    ASIC3 blockade inhibits durovascular and nitric oxide‐mediated trigeminal pain
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    Flotillin-mediated membrane fluidity controls peptidoglycan synthesis and MreB movement
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    Cyclin dependent kinase inhibitor 2A and miR-671-5p expression profile in Iranian glioblastoma multiforme
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    Jag1 Modulates an Oscillatory Dll1-Notch-Hes1 Signaling Module to Coordinate Growth and Fate of Pancreatic Progenitors
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    Patient-derived pancreatic tumour organoids identify therapeutic responses to oncolytic adenoviruses
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Sites of Circadian Clock Neuron Plasticity Mediate Sensory Integration and Entrainment
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    Strengthening of the Efferent Olivocochlear System Leads to Synaptic Dysfunction and Tonotopy Disruption of a Central Auditory Nucleus
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    Traumatic Brain Injury Preserves Firing Rates but Disrupts Laminar Oscillatory Coupling and Neuronal Entrainment in Hippocampal CA1
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    Changes of Ocular Dimensions as a Marker of Disease Progression in a Murine Model of Pigmentary Glaucoma
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    Vascular actions of peripheral CGRP in migraine-like photophobia in mice - Bianca N Mason, Anne-Sophie Wattiez, Louis K Balcziak, Adisa Kuburas, William J Kutschke, Andrew F Russo, 2020
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    Long-Term Programming of CD8 T Cell Immunity by Perinatal Exposure to Glucocorticoids
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    TBK1 and IKKε Act Redundantly to Mediate STING-Induced NF-κB Responses in Myeloid Cells
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    The p21‐activated kinase 2 (PAK2), but not PAK1, regulates contraction‐stimulated skeletal muscle glucose transport
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    The Acute Effects of Amyloid-Beta1–42 on Glutamatergic Receptor and Transporter Expression in the Mouse Hippocampus
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    Drosophila model to study Retinitis pigmentosa pathology associated with mutations in the core splicing factor Prp8
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    Single-Cell Transcriptome Profiling Reveals β Cell Maturation in Stem Cell-Derived Islets after Transplantation
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    Cerebrovascular amyloid Angiopathy in bioengineered vessels is reduced by high-density lipoprotein particles enriched in Apolipoprotein E
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    Ca2+ entry through NaV channels generates submillisecond axonal Ca2+ signaling
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    Retinal topography in two species of flamingo (Phoenicopteriformes: Phoenicopteridae)
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  181. elifesciences.org elifesciences.org
    CD163 and pAPN double-knockout pigs are resistant to PRRSV and TGEV and exhibit decreased susceptibility to PDCoV while maintaining normal production performance
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      DOI: 10.7554/eLife.57132

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    A Single Human VH-gene Allows for a Broad-Spectrum Antibody Response Targeting Bacterial Lipopolysaccharides in the Blood
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    Interactome Mapping Provides a Network of Neurodegenerative Disease Proteins and Uncovers Widespread Protein Aggregation in Affected Brains
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    Profiling of myristoylation in Toxoplasma gondii reveals an N-myristoylated protein important for host cell penetration
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    Evolutionary expansion of apical extracellular matrix is required for the elongation of cells in a novel structure
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    Splicing variation of BMP2K balances abundance of COPII assemblies and autophagic degradation in erythroid cells
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    Transcriptional Correlates of Tolerance and Lethality in Mice Predict Ebola Virus Disease Patient Outcomes
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    Islet O-GlcNAcylation Is Required for Lipid Potentiation of Insulin Secretion through SERCA2
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    Maturational Changes in Mouse Cutaneous Touch and Piezo2-Mediated Mechanotransduction
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    Bioenergetic Crosstalk between Mesenchymal Stem Cells and various Ocular Cells through the intercellular trafficking of Mitochondria
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      DOI: 10.7150/thno.46332

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    Gata3-controlled nucleosome eviction drives Myc enhancer activity in T-cell development and leukemia
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      DOI: 10.1158/2159-8290.CD-19-0471

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    Phenformin Inhibits Hedgehog-Dependent Tumor Growth through a Complex I-Independent Redox/Corepressor Module
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    Protein synthesis inhibition promotes nitric oxide generation and activation of CGKII-dependent downstream signaling pathways in the retina
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    Predictive Nephrotoxicity Profiling of a Novel Antifungal Small Molecule in Comparison to Amphotericin B and Voriconazole
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    Licochalcone D Induces ROS-Dependent Apoptosis in Gefitinib-Sensitive or Resistant Lung Cancer Cells by Targeting EGFR and MET
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      DOI: 10.3390/biom10020297

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    Tissue-resident macrophages promote extracellular matrix homeostasis in the mammary gland stroma of nulliparous mice
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      DOI: 10.7554/eLife.57438

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