1,297 Matching Annotations
  1. Jun 2024
  2. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
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    ncbi.nlm.nih.gov/pmc/articles/PMC11210859/
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chemo‐small extracellular vesicles released in cisplatin‐resistance ovarian cancer cells are regulated by the lysosomal function
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    ncbi.nlm.nih.gov/pmc/articles/PMC11212338/
  4. www.cell.com www.cell.com
    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
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    cell.com/iscience/abstract/S2589-0042(24)01356-7
  5. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    ncbi.nlm.nih.gov/pmc/articles/PMC11209011/
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    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/10.1002/1878-0261.13672
  7. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11142209/
  8. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
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    ncbi.nlm.nih.gov/pmc/articles/PMC11142172/
  9. www.sciencedirect.com www.sciencedirect.com
    Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER
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    sciencedirect.com/science/article/pii/S2211124724006867
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11178498/
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11182644/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Caspase-4 promotes metastasis and interferon-γ-induced pyroptosis in lung adenocarcinoma
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    ncbi.nlm.nih.gov/pmc/articles/PMC11161495/
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    Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus
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    rupress.org/jem/article/221/8/e20232066/276809/Gain-of-function-human-UNC93B1-variants-cause
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    Structural basis of human U5 snRNP late biogenesis and recycling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7616108/
  15. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11160645/
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chlormequat Chloride Inhibits TM3 Leydig Cell Growth via Ferroptosis-Initiated Inflammation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11171675/
  17. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11162783/
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An essential role for EROS in redox-dependent endothelial signal transduction
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    ncbi.nlm.nih.gov/pmc/articles/PMC11153901/
  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11148769/
  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apoptosis signal-regulating kinase 1 promotes inflammation in senescence and aging
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    ncbi.nlm.nih.gov/pmc/articles/PMC11153534/
  21. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An oncogenic enhancer promotes melanoma progression via regulating ETV4 expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11157841/
  22. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
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    ncbi.nlm.nih.gov/pmc/articles/PMC11102494/
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans
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    ncbi.nlm.nih.gov/pmc/articles/PMC11116816/
  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and Pharmacological Targeting of Treatment-Resistant, Stem-like Breast Cancer Cells for Combination Therapy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11118419/
  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127050/
  26. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Synthetic protein circuits for programmable control of mammalian cell death
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    ncbi.nlm.nih.gov/pmc/articles/PMC11127782/
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11145263/
  28. www.sciencedirect.com www.sciencedirect.com
    Lineage specification in glioblastoma is regulated by METTL7B
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    sciencedirect.com/science/article/pii/S2211124724006375
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Area postrema neurons mediate interleukin-6 function in cancer cachexia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11144211/
  30. www.biorxiv.org www.biorxiv.org
    Alpha-defensin binding expands human adenovirus tropism
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    biorxiv.org/content/10.1101/2024.05.30.596681v1
  31. www.biorxiv.org www.biorxiv.org
    Aging represses lung tumorigenesis and alters tumor suppression
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    biorxiv.org/content/10.1101/2024.05.28.596319v1
  32. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11135424/
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity
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    ncbi.nlm.nih.gov/pmc/articles/PMC11143221/
  34. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure
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    ncbi.nlm.nih.gov/pmc/articles/PMC11132451/
  35. May 2024
  36. www.biorxiv.org www.biorxiv.org
    Compaction of Active Chromatin Domains and Promoters by H3S10 Phosphorylation during Mitosis Preserves Interphase-Specific Chromatin Structure and Function
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    biorxiv.org/content/10.1101/2024.05.20.595059v1
  37. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Tsyn-seq: a T cell synapse-based antigen identification platform
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    pmc.ncbi.nlm.nih.gov/articles/PMC11065584/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers
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    ncbi.nlm.nih.gov/pmc/articles/PMC11088660/
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension
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    ncbi.nlm.nih.gov/pmc/articles/PMC11089701/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094423/
  41. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human lung cancer-derived mesenchymal stem cells promote tumor growth and immunosuppression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11097554/
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
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    ncbi.nlm.nih.gov/pmc/articles/PMC11098743/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11087762/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes
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    ncbi.nlm.nih.gov/pmc/articles/PMC11091208/
  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11091123/
  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OGT and OGA gene-edited human induced pluripotent stem cells for dissecting the functional roles of O-GlcNAcylation in hematopoiesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11094211/
  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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    ncbi.nlm.nih.gov/pmc/articles/PMC11095939/
  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC10843145/
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11090050/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting senescent cells with NKG2D-CAR T cells
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    ncbi.nlm.nih.gov/pmc/articles/PMC11069534/
  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11078192/
  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TruD technology for the study of epi- and endothelial tubes in vitro
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    ncbi.nlm.nih.gov/pmc/articles/PMC11086873/
  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11082183/
  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
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    ncbi.nlm.nih.gov/pmc/articles/PMC11082369/
  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs
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    ncbi.nlm.nih.gov/pmc/articles/PMC11068581/
  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11076557/
  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11081508/
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection
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    ncbi.nlm.nih.gov/pmc/articles/PMC11081172/
  59. 52.53.155.43 52.53.155.43
    Systemic Phospho-Defective and Phospho-Mimetic Drp1 Mice Exhibit Normal Growth and Development with Altered Anxiety-like Behavior
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    52.53.155.43/d1e2697f64d96d78a321757845140047d6880af7/PIIS2589004224010964-html.html
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC11149630/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimisation of a primary human CAR‐NK cell manufacturing pipeline
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    ncbi.nlm.nih.gov/pmc/articles/PMC11063921/
  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling
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    ncbi.nlm.nih.gov/pmc/articles/PMC11060976/
  63. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
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    ncbi.nlm.nih.gov/pmc/articles/PMC11059174/
  64. www.sciencedirect.com www.sciencedirect.com
    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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    sciencedirect.com/science/article/pii/S2211124724005023
  65. www.mdpi.com www.mdpi.com
    TurboID-Based IRE1 Interactome Reveals Participants of the Endoplasmic Reticulum-Associated Protein Degradation Machinery in the Human Mast Cell Leukemia Cell Line HMC-1.2
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    mdpi.com/2073-4409/13/9/747
  66. Apr 2024
  67. www.biorxiv.org www.biorxiv.org
    Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration
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    biorxiv.org/content/10.1101/2024.04.08.588584v1
  68. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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    ncbi.nlm.nih.gov/pmc/articles/PMC11030420/
  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIS counteracts PTBP2 and regulates alternative exon usage in neurons
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    ncbi.nlm.nih.gov/pmc/articles/PMC11045219/
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Remodeling in Patient‐Derived Colorectal Cancer Models
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    ncbi.nlm.nih.gov/pmc/articles/PMC11040356/
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer
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    ncbi.nlm.nih.gov/pmc/articles/PMC11055868/
  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy
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    ncbi.nlm.nih.gov/pmc/articles/PMC11055956/
  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/dCas9-Tet1-Mediated DNA Methylation Editing
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    ncbi.nlm.nih.gov/pmc/articles/PMC11056002/
  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014585/
  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases
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    ncbi.nlm.nih.gov/pmc/articles/PMC11050236/
  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HepG2BD: A Novel and Versatile Cell Line with Inducible HDV Replication and Constitutive HBV Expression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11053718/
  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
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    ncbi.nlm.nih.gov/pmc/articles/PMC11052099/
  78. www.sciencedirect.com www.sciencedirect.com
    The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
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    sciencedirect.com/science/article/pii/S1534580724002284
  79. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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    rupress.org/jcb/article/223/6/e202308013/276631/WW-domains-form-a-folded-type-of-nuclear
  80. www.sciencedirect.com www.sciencedirect.com
    Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
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    sciencedirect.com/science/article/pii/S2666379124001903
  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles
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    ncbi.nlm.nih.gov/pmc/articles/PMC11012118/
  82. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC11014484/
  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    epHero – a tandem-fluorescent probe to track the fate of apoptotic cells during efferocytosis
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    ncbi.nlm.nih.gov/pmc/articles/PMC11024195/
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
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    ncbi.nlm.nih.gov/pmc/articles/PMC11100297/
  85. www.biorxiv.org www.biorxiv.org
    Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities
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    biorxiv.org/content/10.1101/2024.02.28.582578v1
  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis
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    ncbi.nlm.nih.gov/pmc/articles/PMC10925292/
  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner
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    ncbi.nlm.nih.gov/pmc/articles/PMC10945702/
  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
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    ncbi.nlm.nih.gov/pmc/articles/PMC10958617/
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular basis promoting centriole triplet microtubule assembly
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  134. Feb 2024
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  166. Jan 2024
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    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    Nuclear phosphoproteome reveals Prolyl Isomerase PIN1 as a modulator of oncogene-induced senescence.
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  177. Dec 2023
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    An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
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    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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  186. Nov 2023
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  196. Oct 2023
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    A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
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