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Feb 2022
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Upregulation of CD14 in mesenchymal stromal cells accelerates lipopolysaccharide-induced response and enhances antibacterial properties

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1. scibot 02 Feb 2022
  
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  DOI: 10.1016/j.isci.2022.103759
  
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sciencedirect.com/science/article/pii/S2589004222000293
Jan 2022
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SARS-CoV-2 Omicron-B.1.1.529 leads to widespread escape from neutralizing antibody responses

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1. scibot 28 Jan 2022
  
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  plasmid_8454
  
  DOI: 10.1016/j.cell.2021.12.046
  
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sciencedirect.com/science/article/pii/S0092867421015786
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Isolation and characterization of the immune cell fraction from murine brain tumor microenvironment

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1. scibot 21 Jan 2022
  
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  DOI: 10.1016/j.xpro.2021.101106
  
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sciencedirect.com/science/article/pii/S2666166721008121
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Presynaptic mechanisms underlying GABAB-receptor-mediated inhibition of spontaneous neurotransmitter release

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1. scibot 19 Jan 2022
  
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  AddgeneCatalog # 8454
  
  DOI: 10.1016/j.celrep.2021.110255
  
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sciencedirect.com/science/article/pii/S2211124721017678
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Lysoptosis is an evolutionarily conserved cell death pathway moderated by intracellular serpins

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1. scibot 15 Jan 2022
  
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  DOI: 10.1038/s42003-021-02953-x
  
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nature.com/articles/s42003-021-02953-x
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Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins

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1. scibot 12 Jan 2022
  
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  DOI: 10.1016/j.cell.2021.12.021
  
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sciencedirect.com/science/article/pii/S0092867421014847
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Restriction of extracellular lipids renders pancreatic cancer dependent on autophagy

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1. scibot 11 Jan 2022
  
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  DOI: 10.1186/s13046-021-02231-y
  
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link.springer.com/article/10.1186/s13046-021-02231-y
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Discovery of small-molecule positive allosteric modulators of Parkin E3 ligase

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1. scibot 06 Jan 2022
  
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  DOI: 10.1016/j.isci.2021.103650
  
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sciencedirect.com/science/article/pii/S2589004221016205
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A functional taxonomy of tumor suppression in oncogenic KRAS-driven lung cancer

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1. scibot 05 Jan 2022
  
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  Addgene_8454
  
  DOI: 10.1158/2159-8290.CD-20-1325
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8292166/
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Epigenetic regulation of ferroptosis via ETS1/miR-23a-3p/ACSL4 axis mediates sorafenib resistance in human hepatocellular carcinoma

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1. scibot 04 Jan 2022
  
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  RRID:Addgene_8454
  
  DOI: 10.1186/s13046-021-02208-x
  
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link.springer.com/article/10.1186/s13046-021-02208-x
Dec 2021
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WASp triggers mechanosensitive actin patches to facilitate immune cell migration in dense tissues

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1. scibot 17 Dec 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.devcel.2021.11.024
  
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sciencedirect.com/science/article/pii/S1534580721009497
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Defective brown adipose tissue thermogenesis and impaired glucose metabolism in mice lacking Letmd1

1
1. scibot 15 Dec 2021
  
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  Plasmid_8454
  
  DOI: 10.1016/j.celrep.2021.110104
  
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sciencedirect.com/science/article/pii/S2211124721015989
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Extracellular cathepsin Z signals through the α5 integrin and augments NLRP3 inflammasome activation

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1. scibot 07 Dec 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.jbc.2021.101459
  
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sciencedirect.com/science/article/pii/S0021925821012680
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Knockdown of Astrocytic Monocarboxylate Transporter 4 in the Motor Cortex Leads to Loss of Dendritic Spines and a Deficit in Motor Learning

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1. scibot 02 Dec 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1007/s12035-021-02651-z
  
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link.springer.com/article/10.1007/s12035-021-02651-z
Nov 2021
elifesciences.org elifesciences.org

Mitochondrial respiration contributes to the interferon gamma response in antigen-presenting cells

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1. scibot 24 Nov 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.65109
  
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elifesciences.org/articles/65109
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

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1. scibot 24 Nov 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.110056
  
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sciencedirect.com/science/article/pii/S2211124721015424
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Soluble guanylate cyclase signalling mediates etoposide resistance in progressing small cell lung cancer

1
1. scibot 21 Nov 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41467-021-26823-6
  
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nature.com/articles/s41467-021-26823-6
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MTHFD2 is a metabolic checkpoint controlling effector and regulatory T cell fate and function

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1. scibot 12 Nov 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.immuni.2021.10.011
  
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sciencedirect.com/science/article/pii/S1074761321004489
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TIAM1-RAC1 promote small-cell lung cancer cell survival through antagonizing Nur77-induced BCL2 conformational change

1
1. scibot 10 Nov 2021
  
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  plasmid_8454
  
  DOI: 10.1016/j.celrep.2021.109979
  
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sciencedirect.com/science/article/pii/S2211124721014583
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Convergence of distinct signaling pathways on synaptic scaling to trigger rapid antidepressant action

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1. scibot 03 Nov 2021
  
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  Addgene, Cat# 8454
  
  DOI: 10.1016/j.celrep.2021.109918
  
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sciencedirect.com/science/article/pii/S2211124721013917
Oct 2021
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GEM-IL: A highly responsive fluorescent lactate indicator

1
1. scibot 22 Oct 2021
  
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  8454
  
  DOI: 10.1016/j.crmeth.2021.100092
  
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sciencedirect.com/science/article/pii/S2667237521001478
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A guide in lentiviral vector production for hard-to-transfect cells, using cardiac-derived c-kit expressing cells as a model system

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1. scibot 02 Oct 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41598-021-98657-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8478948/
Sep 2021
onlinelibrary.wiley.com onlinelibrary.wiley.com

Visualizing looping of two endogenous genomic loci using synthetic zinc-finger proteins with anti-FLAG and anti-HA frankenbodies in living cells

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1. scibot 30 Sep 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1111/gtc.12893
  
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onlinelibrary.wiley.com/doi/10.1111/gtc.12893
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Lrp1 is a host entry factor for Rift Valley fever virus

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1. scibot 24 Sep 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.cell.2021.09.001
  
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sciencedirect.com/science/article/pii/S0092867421010485
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NSD2 dimethylation at H3K36 promotes lung adenocarcinoma pathogenesis

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1. scibot 23 Sep 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.molcel.2021.08.034
  
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sciencedirect.com/science/article/pii/S1097276521007140
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The structural dynamics of macropinosome formation and PI3-kinase-mediated sealing revealed by lattice light sheet microscopy

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1. scibot 04 Sep 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41467-021-25187-1
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8355319/
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Discovery of synthetic lethal and tumor suppressor paralog pairs in the human genome

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1. scibot 02 Sep 2021
  
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  Addgene: 8454
  
  DOI: 10.1016/j.celrep.2021.109597
  
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sciencedirect.com/science/article/pii/S2211124721010354
Aug 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Overlapping roles of JIP3 and JIP4 in promoting axonal transport of lysosomes in human iPSC-derived neurons

1
1. scibot 16 Aug 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1091/mbc.E20-06-0382
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8351540/
www.embopress.org www.embopress.org

The biochemical basis of mitochondrial dysfunction in Zellweger Spectrum Disorder

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1. scibot 15 Aug 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.15252/embr.202051991
  
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embopress.org/doi/full/10.15252/embr.202051991
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A subthreshold synaptic mechanism regulating BDNF expression and resting synaptic strength

1
1. scibot 15 Aug 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.109467
  
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sciencedirect.com/science/article/pii/S2211124721008901
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RalA and PLD1 promote lipid droplet growth in response to nutrient withdrawal

1
1. scibot 14 Aug 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.109451
  
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sciencedirect.com/science/article/pii/S2211124721008688
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

A Positive Role of c-Myc in Regulating Androgen Receptor and its Splice Variants in Prostate Cancer

1
1. scibot 14 Aug 2021
  
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  plasmid_8454
  
  DOI: 10.1038/s41388-019-0768-8
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6586509/
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Actinin BioID reveals sarcomere crosstalk with oxidative metabolism through interactions with IGF2BP2

1
1. scibot 11 Aug 2021
  
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  Addgene Cat. #8454
  
  DOI: 10.1016/j.celrep.2021.109512
  
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sciencedirect.com/science/article/pii/S2211124721009426
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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors

1
1. scibot 10 Aug 2021
  
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  Plasmid_8454
  
  DOI: 10.1016/j.cell.2018.11.024
  
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sciencedirect.com/science/article/pii/S0092867418315162
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The CEP19-RABL2 GTPase Complex Binds IFT-B to Initiate Intraflagellar Transport at the Ciliary Base

1
1. scibot 09 Aug 2021
  
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  plasmid_8454
  
  DOI: 10.1016/j.devcel.2017.05.016
  
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sciencedirect.com/science/article/pii/S1534580717304240
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Untitled document

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1. scibot 07 Aug 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.chembiol.2018.10.026
  
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sciencedirect.com/science/article/pii/S2451945618303866
www.nature.com www.nature.com

Untitled document

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1. scibot 06 Aug 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41598-018-37940-6
  
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nature.com/articles/s41598-018-37940-6
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Exosome RNA Unshielding Couples Stromal Activation to Pattern Recognition Receptor Signaling in Cancer

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1. scibot 06 Aug 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.cell.2017.06.031
  
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sciencedirect.com/science/article/pii/S0092867417307158
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Ribosome ADP-ribosylation inhibits translation and maintains proteostasis in cancers

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1. scibot 31 Jul 2021
  
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  Plasmid No. 8454
  
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A curative combination cancer therapy achieves high fractional cell killing through low cross-resistance and drug additivity

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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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The Leukemogenic TCF3-HLF Complex Rewires Enhancers Driving Cellular Identity and Self-Renewal Conferring EP300 Vulnerability

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Control of Germinal Center Localization and Lineage Stability of Follicular Regulatory T Cells by the Blimp1 Transcription Factor

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Re-programing Chromatin with a Bifunctional LSD1/HDAC Inhibitor Induces Therapeutic Differentiation in DIPG

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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

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Differential Activation of the Transcription Factor IRF1 Underlies the Distinct Immune Responses Elicited by Type I and III Interferons

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Genetic and Functional Dissection of the Role of Individual 5-HT2 Receptors as Entry Receptors for JC Polyomavirus

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A Neuron-Optimized CRISPR/dCas9 Activation System for Robust and Specific Gene Regulation

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MicroRNA-Mediated Suppression of the TGF-β Pathway Confers Transmissible and Reversible CDK4/6 Inhibitor Resistance

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Structural insights into trans-histone regulation of H3K4 methylation by unique histone H4 binding of MLL3/4

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IFI16 Targets the Transcription Factor Sp1 to Suppress HIV-1 Transcription and Latency Reactivation

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  pCMV-VSV-G
  
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Untitled document

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  plasmid_8454
  
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Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

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Control of gasdermin D oligomerization and pyroptosis by the Ragulator-Rag-mTORC1 pathway

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Methods for Modulating the Pathway of NF-κB Using <IndexTerm ID="ITerm1">Short Hairpin RNA (ShRNA)</IndexTerm>

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Protocol for CRISPR-Cas9 modification of glycosylation in 3D organotypic skin models

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Glycogen Synthase Kinase 3 Beta Regulates the Human Aryl Hydrocarbon Receptor Cellular Content and Activity

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  RRID:Addgene_8454
  
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STAG2 loss rewires oncogenic and developmental programs to promote metastasis in Ewing sarcoma

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cell.com/cancer-cell/fulltext/S1535-6108(21)00273-7
currentprotocols.onlinelibrary.wiley.com currentprotocols.onlinelibrary.wiley.com

Efficient Derivation of Excitatory and Inhibitory Neurons from Human Pluripotent Stem Cells Stably Expressing Direct Reprogramming Factors

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currentprotocols.onlinelibrary.wiley.com/doi/10.1002/cpz1.141
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Using the dCas9-KRAB system to repress gene expression in hiPSC-derived NGN2 neurons

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  Plasmid_8454
  
  DOI: 10.1016/j.xpro.2021.100580
  
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Targeted delivery of CRISPR-Cas9 and transgenes enables complex immune cell engineering

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  plasmid_8454
  
  DOI: 10.1016/j.celrep.2021.109207
  
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sciencedirect.com/science/article/pii/S2211124721005568
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The autophagy protein Becn1 improves insulin sensitivity by promoting adiponectin secretion via exocyst binding

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  RRID:Addgene_8454
  
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Rab34 GTPase mediates ciliary membrane formation in the intracellular ciliogenesis pathway

1
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.cub.2021.04.075
  
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The oncogenic E3 ligase TRIP12 suppresses epithelial–mesenchymal transition (EMT) and mesenchymal traits through ZEB1/2

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  RRID:Addgene_8454
  
  DOI: 10.1038/s41420-021-00479-z
  
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SARM1 is a metabolic sensor activated by an increased NMN/NAD+ ratio to trigger axon degeneration

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  DOI: 10.1016/j.neuron.2021.02.009
  
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Role of Aberrant Spontaneous Neurotransmission in SNAP25-Associated Encephalopathies

1
1. scibot 08 May 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.neuron.2020.10.012
  
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cell.com/neuron/fulltext/S0896-6273(20)30808-4
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Drp1 Tubulates the ER in a GTPase-Independent Manner

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  Plasmid_8454
  
  DOI: 10.1016/j.molcel.2020.10.013
  
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Genome-Wide Screens Reveal that Resveratrol Induces Replicative Stress in Human Cells

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  DOI: 10.1016/j.molcel.2020.07.010
  
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m6A Modification Prevents Formation of Endogenous Double-Stranded RNAs and Deleterious Innate Immune Responses during Hematopoietic Development

1
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  Plasmid_8454
  
  DOI: 10.1016/j.immuni.2020.05.003
  
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An Excitable Ras/PI3K/ERK Signaling Network Controls Migration and Oncogenic Transformation in Epithelial Cells

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  Plasmid_8454
  
  DOI: 10.1016/j.devcel.2020.08.001
  
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sciencedirect.com/science/article/pii/S1534580720305992
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Non-canonical Glutamate-Cysteine Ligase Activity Protects against Ferroptosis

1
1. scibot 30 Apr 2021
  
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  Cat#: 8454
  
  DOI: 10.1016/j.cmet.2020.12.007
  
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Psychedelic-inspired drug discovery using an engineered biosensor

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1. scibot 29 Apr 2021
  
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  8454
  
  DOI: 10.1016/j.cell.2021.03.043
  
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www-sciencedirect-com.ezproxy.rice.edu/science/article/pii/S0092867421003743
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Inhibitory CD161 receptor identified in glioma-infiltrating T cells by single-cell analysis

1
1. scibot 24 Apr 2021
  
  in Public
  
  Addgene_8454
  
  DOI: 10.1016/j.cell.2021.01.022
  
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TBL1XR1 Mutations Drive Extranodal Lymphoma by Inducing a Pro-tumorigenic Memory Fate

1
1. scibot 23 Apr 2021
  
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  plasmid_8454
  
  DOI: 10.1016/j.cell.2020.05.049
  
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Immunogenomic Landscape of Hematological Malignancies

1
1. scibot 17 Apr 2021
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.ccell.2020.06.002
  
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sciencedirect.com/science/article/pii/S1535610820302750
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SETD5-Coordinated Chromatin Reprogramming Regulates Adaptive Resistance to Targeted Pancreatic Cancer Therapy

1
1. scibot 17 Apr 2021
  
  in Public
  
  Addgene_8454
  
  DOI: 10.1016/j.ccell.2020.04.014
  
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sciencedirect.com/science/article/pii/S1535610820302130
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SEED-MEDIATED RNA INTERFERENCE OF ANDROGEN SIGNALING AND SURVIVAL NETWORKS INDUCES CELL DEATH IN PROSTATE CANCER CELLS

1
1. scibot 15 Apr 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.omtn.2021.03.002
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8022159/
Mar 2021
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PRMT6 methylation of RCC1 regulates mitosis, tumorigenicity, and radiation response of glioblastoma stem cells

1
1. scibot 22 Mar 2021
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.molcel.2021.01.015
  
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A Comprehensive Map of the Monocyte-Derived Dendritic Cell Transcriptional Network Engaged upon Innate Sensing of HIV

1
1. scibot 18 Mar 2021
  
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  plasmid_8454
  
  DOI: 10.1016/j.celrep.2019.12.054
  
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p53 Activates the Long Noncoding RNA Pvt1b to Inhibit Myc and Suppress Tumorigenesis

1
1. scibot 18 Mar 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.molcel.2019.12.014
  
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sciencedirect.com/science/article/pii/S109727651930927X
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Amino acids-Rab1A-mTORC1 signaling controls whole-body glucose homeostasis

1
1. scibot 17 Mar 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.108830
  
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sciencedirect.com/science/article/pii/S2211124721001443
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Identification of a long non-coding RNA regulator of liver carcinoma cell survival

1
1. scibot 09 Mar 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41419-021-03453-w
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7884843/
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CtBP1-Mediated Membrane Fission Contributes to Effective Recycling of Synaptic Vesicles

1
1. scibot 03 Mar 2021
  
  in Public
  
  Plasmid_8454
  
  DOI: 10.1016/j.celrep.2020.01.079
  
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sciencedirect.com/science/article/pii/S2211124720301042
Feb 2021
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Tracking cells in epithelial acini by light sheet microscopy reveals proximity effects in breast cancer initiation

1
1. scibot 26 Feb 2021
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.54066
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7373425/
www.nature.com www.nature.com

Genome-wide CRISPR/Cas9-knockout in human induced Pluripotent Stem Cell (iPSC)-derived macrophages

1
1. scibot 25 Feb 2021
  
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  Addgene # 8454
  
  DOI: 10.1038/s41598-021-82137-z
  
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nature.com/articles/s41598-021-82137-z
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Targeting EphA2 suppresses hepatocellular carcinoma initiation and progression by dual inhibition of JAK1/STAT3 and AKT signaling

1
1. scibot 25 Feb 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.108765
  
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sciencedirect.com/science/article/pii/S2211124721000784
www.cell.com www.cell.com

A Global Map of G Protein Signaling Regulation by RGS Proteins

1
1. scibot 24 Feb 2021
  
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  Plasmid_8454
  
  DOI: 10.1016/j.cell.2020.08.052
  
  Resource: RRID:Addgene_8454
  
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cell.com/cell/fulltext/S0092-8674(20)31140-5
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TAMEP are brain tumor parenchymal cells controlling neoplastic angiogenesis and progression

1
1. scibot 17 Feb 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.cels.2021.01.002
  
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sciencedirect.com/science/article/pii/S2405471221000363
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Gαo is a major determinant of cAMP signaling in the pathophysiology of movement disorders

1
1. scibot 09 Feb 2021
  
  in Public
  
  Addgene_8454
  
  DOI: 10.1016/j.celrep.2021.108718
  
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sciencedirect.com/science/article/pii/S2211124721000310
Jan 2021
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Metoclopramide treatment blocks CD93-signaling-mediated self-renewal of chronic myeloid leukemia stem cells

1
1. scibot 27 Jan 2021
  
  in Public
  
  pCMV-VSV-G
  
  DOI: 10.1016/j.celrep.2020.108663
  
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sciencedirect.com/science/article/pii/S2211124720316521
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FOS licenses early events in stem cell activation driving skeletal muscle regeneration

1
1. scibot 27 Jan 2021
  
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  Addgene_8454
  
  DOI: 10.1016/j.celrep.2020.108656
  
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sciencedirect.com/science/article/pii/S2211124720316454
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Inhibition of Tumor VEGFR2 Induces Serine 897 EphA2-Dependent Tumor Cell Invasion and Metastasis in NSCLC

1
1. scibot 27 Jan 2021
  
  in Public
  
  Addgene_8454
  
  DOI: 10.1016/j.celrep.2020.107568
  
  Resource: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S2211124720305179
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Failed Apoptosis Enhances Melanoma Cancer Cell Aggressiveness

1
1. scibot 15 Jan 2021
  
  in Public
  
  Plasmid_8454
  
  DOI: 10.1016/j.celrep.2020.107731
  
  Resource: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S2211124720307117
elifesciences.org elifesciences.org

Neuronal hyperexcitability is a DLK-dependent trigger of herpes simplex virus reactivation that can be induced by IL-1

1
1. scibot 06 Jan 2021
  
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  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.58037
  
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elifesciences.org/articles/58037
Dec 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Salmonella enterica Infection of Murine and Human Enteroid-Derived Monolayers Elicits Differential Activation of Epithelium-Intrinsic Inflammasomes

1
1. scibot 25 Dec 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1128/IAI.00017-20
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7309616/
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FGF21 Induced by the ASK1-p38 Pathway Promotes Mechanical Cell Competition by Attracting Cells

1
1. scibot 24 Dec 2020
  
  in Public
  
  pCMV-VSV-G
  
  DOI: 10.1016/j.cub.2020.11.052
  
  Resource: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S0960982220317656
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Heterogeneous bone-marrow stromal progenitors drive myelofibrosis via a druggable alarmin axis

1
1. scibot 15 Dec 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.stem.2020.11.004
  
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sciencedirect.com/science/article/pii/S1934590920305427
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Gene Regulatory Network Analysis and Engineering Directs Development and Vascularization of Multilineage Human Liver Organoids

1
1. scibot 13 Dec 2020
  
  in Public
  
  Plasmid_8454
  
  DOI: 10.1016/j.cels.2020.11.002
  
  Resource: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S2405471220304208
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Excessive E2F Transcription in Single Cancer Cells Precludes Transient Cell-Cycle Exit after DNA Damage

1
1. scibot 11 Dec 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2020.108449
  
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sciencedirect.com/science/article/pii/S2211124720314388
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Preclinical Assessment of Efficacy and Safety Analysis of CAR-T Cells (ISIKOK-19) Targeting CD19-Expressing B-Cells for the First Turkish Academic Clinical Trial with Relapsed/Refractory ALL and NHL Patients

1
1. scibot 09 Dec 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.4274/tjh.galenos.2020.2020.0070
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7702660/
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Protocol to Reprogram Human Menstrual Blood-Derived Stromal Cells to Generate AOX15-iPSCs

1
1. scibot 07 Dec 2020
  
  in Public
  
  pCMV-VSV-G
  
  DOI: 10.1016/j.xpro.2020.100183
  
  Resource: RRID:Addgene_8454
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S2666166720301702
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High throughput profiling of undifferentiated pleomorphic sarcomas identifies two main subgroups with distinct immune profile, clinical outcome and sensitivity to targeted therapies

1
1. scibot 07 Dec 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.ebiom.2020.103131
  
  Resource: RRID:Addgene_8454
  
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  RRIDCUR:Validated RRID:Addgene_8454
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sciencedirect.com/science/article/pii/S2352396420305077
Nov 2020
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RACK1 Mediates NLRP3 Inflammasome Activation by Promoting NLRP3 Active Conformation and Inflammasome Assembly

1
1. scibot 24 Nov 2020
  
  in Public
  
  pCMV-VSV-G
  
  DOI: 10.1016/j.celrep.2020.108405
  
  Resource: RRID:Addgene_8454
  
  Curator: @Naa003
  
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sciencedirect.com/science/article/pii/S2211124720313942
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Genome-wide CRISPR Screens Reveal Host Factors Critical for SARS-CoV-2 Infection

1
1. scibot 05 Nov 2020
  
  in Public
  
  Addgene Cat#8454
  
  DOI: 10.1016/j.cell.2020.10.028
  
  Resource: RRID:Addgene_8454
  
  Curator: @evieth
  
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sciencedirect.com/science/article/pii/S0092867420313921
Oct 2020
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Receptor-Driven ERK Pulses Reconfigure MAPK Signaling and Enable Persistence of Drug-Adapted BRAF-Mutant Melanoma Cells

1
1. scibot 31 Oct 2020
  
  in Public
  
  pCMV-VSV-G
  
  DOI: 10.1016/j.cels.2020.10.002
  
  Resource: RRID:Addgene_8454
  
  Curator: @Naa003
  
  SciCrunch record: RRID:Addgene_8454
  
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sciencedirect.com/science/article/pii/S2405471220303707
pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov

Cetuximab-Mediated Protection from Hypoxia- Induced Cell Death: Implications for Therapy Sequence in Colorectal Cancer

1
1. scibot 27 Oct 2020
  
  in Public
  
  Addgene_8454
  
  DOI: 10.3390/cancers12103050
  
  Resource: RRID:Addgene_8454
  
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  RRIDCUR:Validated RRID:Addgene_8454
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pubmed.ncbi.nlm.nih.gov/33092032/
Sep 2020
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Blockade of Oncogenic NOTCH1 with the SERCA Inhibitor CAD204520 in T Cell Acute Lymphoblastic Leukemia

1
1. scibot 26 Sep 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1016/j.chembiol.2020.04.002
  
  Resource: RRID:Addgene_8454
  
  Curator: @ethanbadger
  
  SciCrunch record: RRID:Addgene_8454
  
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A Three-Dimensional Alzheimer’s Disease Cell Culture Model Using iPSC-Derived Neurons Carrying A246E Mutation in PSEN1

1
1. scibot 26 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.3389/fncel.2020.00151
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7325960/
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A Replication-Competent Vesicular Stomatitis Virus for Studies of SARS-CoV-2 Spike-Mediated Cell Entry and Its Inhibition

1
1. scibot 25 Sep 2020
  
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  plasmid_8454
  
  DOI: 10.1016/j.chom.2020.06.020
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7332447/
academic.oup.com academic.oup.com

Evaluation of an aldo-keto reductase gene signature with prognostic significance in colon cancer via activation of epithelial to mesenchymal transition and the p70S6K pathway

1
1. scibot 25 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1093/carcin/bgaa072
  
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academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgaa072/5867997
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Axon-like protrusions promote small cell lung cancer migration and metastasis

1
1. scibot 23 Sep 2020
  
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  Addgene_8454
  
  DOI: 10.7554/eLife.50616
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6940020/
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Phosphorylated Lamin A/C in the Nuclear Interior Binds Active Enhancers Associated with Abnormal Transcription in Progeria

2
1. scibot 23 Sep 2020
  
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  plasmid_8454
  
  DOI: 10.1016/j.devcel.2020.02.011
  
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  DOI: 10.1016/j.devcel.2020.02.011
  
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sciencedirect.com/science/article/pii/S1534580720301076
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The ACSL3-LPIAT1 signaling drives prostaglandin synthesis in non-small cell lung cancer

1
1. scibot 16 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41388-020-1196-5
  
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nature.com/articles/s41388-020-1196-5
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Generation of two iPS cell lines (HIHDNDi001-A and HIHDNDi001-B) from a Parkinson’s disease patient carrying the heterozygous p.A30P mutation in SNCA

1
1. scibot 16 Sep 2020
  
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  Addgene_8454
  
  DOI: 10.1016/j.scr.2020.101951
  
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sciencedirect.com/science/article/pii/S187350612030252X
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Generation of a human iPSC line (MPIi007-A) from a patient with Metachromatic leukodystrophy

1
1. scibot 15 Sep 2020
  
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  pCMV-VSV-G
  
  DOI: 10.1016/j.scr.2020.101993
  
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Inhibition of MEK1/2 Forestalls the Onset of Acquired Resistance to Entrectinib in Multiple Models of NTRK1-Driven Cancer

1
1. scibot 14 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2020.107994
  
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MYC Drives Temporal Evolution of Small Cell Lung Cancer Subtypes by Reprogramming Neuroendocrine Fate

1
1. scibot 13 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.ccell.2020.05.001
  
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sciencedirect.com/science/article/pii/S153561082030218X
onlinelibrary.wiley.com onlinelibrary.wiley.com

FGF13 promotes metastasis of triple‐negative breast cancer

1
1. scibot 12 Sep 2020
  
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  plasmid_8454
  
  DOI: 10.1002/ijc.32874
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.32874
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Formate induces a metabolic switch in nucleotide and energy metabolism

1
1. scibot 12 Sep 2020
  
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  Addgene_8454
  
  DOI: 10.1038/s41419-020-2523-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7198490/
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Essential Functions of Glycans in Human Epithelia Dissected by a CRISPR-Cas9-Engineered Human Organotypic Skin Model

1
1. scibot 12 Sep 2020
  
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  Addgene_8454
  
  DOI: 10.1016/j.devcel.2020.06.039
  
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pubmed.ncbi.nlm.nih.gov/32710848/
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An Optimized Protocol for Human Direct Cardiac Reprogramming

1
1. scibot 10 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.xpro.2019.100010
  
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sciencedirect.com/science/article/pii/S2666166719300103
elifesciences.org elifesciences.org

Sequentially induced motor neurons from human fibroblasts facilitate locomotor recovery in a rodent spinal cord injury model

1
1. scibot 10 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.52069
  
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elifesciences.org/articles/52069
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Endolysosomal Targeting of Mitochondria Is Integral to BAX-Mediated Mitochondrial Permeabilization during Apoptosis Signaling

1
1. scibot 09 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.devcel.2020.05.014
  
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sciencedirect.com/science/article/pii/S1534580720304032
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CtBP determines ovarian cancer cell fate through repression of death receptors

1
1. scibot 07 Sep 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1038/s41419-020-2455-7
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7181866/
academic.oup.com academic.oup.com

Knockout of USP19 Deubiquitinating Enzyme Prevents Muscle Wasting by Modulating Insulin and Glucocorticoid Signaling

1
1. scibot 04 Sep 2020
  
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  pCMV-VSV-G
  
  DOI: 10.1210/en.2018-00290
  
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academic.oup.com/endo/article/159/8/2966/5035244
journals.plos.org journals.plos.org

JC Virus infected choroid plexus epithelial cells produce extracellular vesicles that infect glial cells independently of the virus attachment receptor

1
1. scibot 04 Sep 2020
  
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  pVSV-G
  
  DOI: 10.1371/journal.ppat.1008371
  
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journals.plos.org/plospathogens/article
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Imprinted Maternally Expressed microRNAs Antagonize Paternally Driven Gene Programs in Neurons

1
1. scibot 03 Sep 2020
  
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  Cat#8454 Addgene
  
  DOI: 10.1016/j.molcel.2020.01.020
  
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sciencedirect.com/science/article/pii/S1097276520300411
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Vimentin Coordinates Protein Turnover at the Aggresome during Neural Stem Cell Quiescence Exit

1
1. scibot 03 Sep 2020
  
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  AddgeneCat#8454
  
  DOI: 10.1016/j.stem.2020.01.018
  
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sciencedirect.com/science/article/pii/S1934590920300187
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E2F-Family Members Engage the PIDDosome to Limit Hepatocyte Ploidy in Liver Development and Regeneration

1
1. scibot 03 Sep 2020
  
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  Addgene plasmid#8454
  
  DOI: 10.1016/j.devcel.2019.12.016
  
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sciencedirect.com/science/article/pii/S1534580719310391
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Recognition of Semaphorin Proteins by P. sordellii Lethal Toxin Reveals Principles of Receptor Specificity in Clostridial Toxins

1
1. scibot 03 Sep 2020
  
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  Addgene plasmid 8454
  
  DOI: 10.1016/j.cell.2020.06.005
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7316060/
www.jneurosci.org www.jneurosci.org

Auxiliary α2δ1 and α2δ3 Subunits of Calcium Channels Drive Excitatory and Inhibitory Neuronal Network Development

1
1. scibot 03 Sep 2020
  
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  Addgene, plasmid #8454
  
  DOI: 10.1523/JNEUROSCI.1707-19.2020
  
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jneurosci.org/content/40/25/4824
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Flexible Usage and Interconnectivity of Diverse Cell Death Pathways Protect against Intracellular Infection

1
1. scibot 03 Sep 2020
  
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  pVSVg plasmid
  
  DOI: 10.1016/j.immuni.2020.07.004
  
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sciencedirect.com/science/article/pii/S1074761320302843
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Mutant p53 Drives Cancer Metastasis via RCP-Mediated Hsp90α Secretion

1
1. scibot 03 Sep 2020
  
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  pVSVg
  
  DOI: 10.1016/j.celrep.2020.107879
  
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sciencedirect.com/science/article/pii/S2211124720308603
Aug 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cohesin-Dependent and -Independent Mechanisms Mediate Chromosomal Contacts between Promoters and Enhancers

1
1. scibot 22 Aug 2020
  
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  plasmid_8454
  
  DOI: 10.1016/j.celrep.2020.107929
  
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ncbi.nlm.nih.gov/pmc/articles/PMC7383238/
Jan 2020
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Cysteine catabolism and the serine biosynthesis pathway support pyruvate production during pyruvate kinase knockdown in pancreatic cancer cells

1
1. scibot 13 Jan 2020
  
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  plasmid_8454
  
  DOI: 10.1186/s40170-019-0205-z
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6937848/
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Modeling of Cisplatin-Induced Signaling Dynamics in Triple-Negative Breast Cancer Cells Reveals Mediators of Sensitivity

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2019.07.070
  
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sciencedirect.com/science/article/pii/S221112471930974X
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Increased expression of heme-binding protein 1 early in Alzheimer's disease is linked to neurotoxicity

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.47498
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6739868/
www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov

Genetic interactions of G-quadruplexes in humans

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.7554/eLife.46793
  
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ncbi.nlm.nih.gov/pmc/articles/PMC6615864/
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Id4 Downstream of Notch2 Maintains Neural Stem Cell Quiescence in the Adult Hippocampus

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2019.07.014
  
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sciencedirect.com/science/article/pii/S2211124719309040
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Unique and Shared Epigenetic Programs of the CREBBP and EP300 Acetyltransferases in Germinal Center B Cells Reveal Targetable Dependencies in Lymphoma

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.immuni.2019.08.006
  
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sciencedirect.com/science/article/pii/S1074761319303322
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Activation of PARP-1 by snoRNAs Controls Ribosome Biogenesis and Cell Growth via the RNA Helicase DDX21

1
1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.molcel.2019.06.020
  
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sciencedirect.com/science/article/pii/S1097276519304769
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1. scibot 13 Jan 2020
  
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  RRID:Addgene_8454
  
  DOI: 10.1016/j.celrep.2018.12.043
  
  Resource: RRID:Addgene_8454
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718319739
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Translational Control through Differential Ribosome Pausing during Amino Acid Limitation in Mammalian Cells

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1. scibot 13 Jan 2020
  
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  Addgene_8454
  
  DOI: 10.1016/j.molcel.2018.06.041
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Addgene_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1097276518305161
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The Lineage-Defining Transcription Factors SOX2 and NKX2-1 Determine Lung Cancer Cell Fate and Shape the Tumor Immune Microenvironment

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1. scibot 13 Jan 2020
  
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  Plasmid_8454
  
  DOI: 10.1016/j.immuni.2018.09.020
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Plasmid_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1074761318304357
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RbAp48 Protein Is a Critical Component of GPR158/OCN Signaling and Ameliorates Age-Related Memory Loss

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1. scibot 13 Jan 2020
  
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  Plasmid_8454
  
  DOI: 10.1016/j.celrep.2018.09.077
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Plasmid_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718315377
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The Epigenetic State of PRDM16-Regulated Enhancers in Radial Glia Controls Cortical Neuron Position

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1. scibot 13 Jan 2020
  
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  Addgene_8454
  
  DOI: 10.1016/j.neuron.2018.04.033
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Addgene_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S0896627318303684
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Dppa2/4 Facilitate Epigenetic Remodeling during Reprogramming to Pluripotency

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1. scibot 13 Jan 2020
  
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  Addgene_8454
  
  DOI: 10.1016/j.stem.2018.08.001
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Addgene_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1934590918303862
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Untitled document

1
1. scibot 13 Jan 2020
  
  in Public
  
  plasmid_8454
  
  DOI: 10.7554/eLife.41351
  
  Resource: RRID:Addgene_8454
  
  Curator: @evieth
  
  SciCrunch record: plasmid_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6351101/
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Mitochondrial Stasis Reveals p62-Mediated Ubiquitination in Parkin-Independent Mitophagy and Mitigates Nonalcoholic Fatty Liver Disease

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1. scibot 12 Jan 2020
  
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  plasmid_8454
  
  DOI: 10.1016/j.cmet.2018.06.014
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: plasmid_8454
  
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  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S1550413118303966
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Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  Plasmid_8454
  
  DOI: 10.1016/j.celrep.2018.09.071
  
  Resource: RRID:Addgene_8454
  
  Curator: @Jmenke
  
  SciCrunch record: Plasmid_8454
  
  What is this?
  
  RRID:Addgene_8454 RRIDCUR:Validated
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sciencedirect.com/science/article/pii/S2211124718315316
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Untitled document

1
1. scibot 12 Jan 2020
  
  in Public
  
  RRID:Addgene_8454
  
  DOI: 10.1038/s41598-018-37940-6
  
  Resource: RRID:Addgene_8454
  
  Curator: @evieth
  
  SciCrunch record: RRID:Addgene_8454
  
  What is this?
  
  RRID:Addgene_8454 RRIDCUR:Validated
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ncbi.nlm.nih.gov/pmc/articles/PMC6362041/

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