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    RNASeq highlights ATF6 pathway regulators for CHO cell engineering with different impacts of ATF6β and WFS1 knockdown on fed-batch production of IgG1
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    PCDH17 restricts dendritic spine morphogenesis by regulating ROCK2-dependent control of the actin cytoskeleton, modulating emotional behavior
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    Multiplexed single-cell lineage tracing of mitotic kinesin inhibitor resistance in glioblastoma
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    Antiviral activity of intracellular nanobodies targeting the influenza virus RNA-polymerase core
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    Chemo‐small extracellular vesicles released in cisplatin‐resistance ovarian cancer cells are regulated by the lysosomal function
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    An HIV-1 CRISPR-Cas9 membrane trafficking screen reveals a role for PICALM intersecting endolysosomes and immunity
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    1. scibot 30 Jun 2024
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    cell.com/iscience/abstract/S2589-0042(24)01356-7
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    CRISPR/Cas9 screening reveals a distinct class of MHC-I binders with precise HLA-peptide recognition
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    cell.com/iscience/abstract/S2589-0042(24)01345-2
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    FEBS Press
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  10. Jun 2024
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    A genome-scale screen identifies sulfated glycosaminoglycans as pivotal in epithelial cell damage by Candida albicans
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    Absence of c-Maf and IL-10 enables Type I IFN enhancement of innate responses to low-dose LPS in alveolar macrophages
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    1. scibot 21 Jun 2024
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    Deciphering ER stress-unfolded protein response relationship by visualizing unfolded proteins in the ER
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    The DNA damage-independent ATM signalling maintains CBP/DOT1L axis in MLL rearranged acute myeloid leukaemia
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    1. scibot 20 Jun 2024
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    Expression of modified FcγRI enables myeloid cells to elicit robust tumor-specific cytotoxicity
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    1. scibot 20 Jun 2024
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    Caspase-4 promotes metastasis and interferon-γ-induced pyroptosis in lung adenocarcinoma
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    1. scibot 20 Jun 2024
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    Gain-of-function human UNC93B1 variants cause systemic lupus erythematosus and chilblain lupus
    1
    1. scibot 20 Jun 2024
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    Structural basis of human U5 snRNP late biogenesis and recycling
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  19. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Calcium Signaling Regulates Branched-Chain Amino Acid Catabolism in Fibrolamellar Carcinoma
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  20. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chlormequat Chloride Inhibits TM3 Leydig Cell Growth via Ferroptosis-Initiated Inflammation
    1
    1. scibot 15 Jun 2024
      pCMV-VSV-G

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    Dux activates metabolism-lactylation-MET network during early iPSC reprogramming with Brg1 as the histone lactylation reader
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    An essential role for EROS in redox-dependent endothelial signal transduction
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    A structure-function analysis shows SARS-CoV-2 BA.2.86 balances antibody escape and ACE2 affinity
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  24. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Apoptosis signal-regulating kinase 1 promotes inflammation in senescence and aging
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  25. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    An oncogenic enhancer promotes melanoma progression via regulating ETV4 expression
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    Mitochondrial respiratory function is preserved under cysteine starvation via glutathione catabolism in NSCLC
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  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Large-scale mutational analysis identifies UNC93B1 variants that drive TLR-mediated autoimmunity in mice and humans
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    Identification and Pharmacological Targeting of Treatment-Resistant, Stem-like Breast Cancer Cells for Combination Therapy
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  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Genome-wide CRISPR screens in spheroid culture reveal that the tumor suppressor LKB1 inhibits growth via the PIKFYVE lipid kinase
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    Synthetic protein circuits for programmable control of mammalian cell death
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    Tau fibrils induce nanoscale membrane damage and nucleate cytosolic tau at lysosomes
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    Lineage specification in glioblastoma is regulated by METTL7B
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  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Area postrema neurons mediate interleukin-6 function in cancer cachexia
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  34. www.biorxiv.org www.biorxiv.org
    Alpha-defensin binding expands human adenovirus tropism
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    Aging represses lung tumorigenesis and alters tumor suppression
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  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNMT3B splicing dysregulation mediated by SMCHD1 loss contributes to DUX4 overexpression and FSHD pathogenesis
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    The thioredoxin system determines CHK1 inhibitor sensitivity via redox-mediated regulation of ribonucleotide reductase activity
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  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure
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  39. May 2024
  40. www.biorxiv.org www.biorxiv.org
    Compaction of Active Chromatin Domains and Promoters by H3S10 Phosphorylation during Mitosis Preserves Interphase-Specific Chromatin Structure and Function
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  41. aacrjournals.org aacrjournals.org
    Tsyn-seq: a T cell synapse-based antigen identification platform
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      DOI: 10.1158/2326-6066.CIR-23-0467

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    aacrjournals.org/cancerimmunolres/article/12/5/530/745120/Tsyn-Seq-a-T-cell-Synapse-Based-Antigen
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Valrubicin-loaded immunoliposomes for specific vesicle-mediated cell death in the treatment of hematological cancers
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  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    N6-methyladenosine modification of KLF2 may contribute to endothelial-to-mesenchymal transition in pulmonary hypertension
    1
    1. scibot 19 May 2024
      pCMV-VSV-G

      DOI: 10.1186/s11658-024-00590-w

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    ncbi.nlm.nih.gov/pmc/articles/PMC11089701/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting CCL2/CCR2 Signaling Overcomes MEK Inhibitor Resistance in Acute Myeloid Leukemia
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    1. scibot 19 May 2024
      VSV-G

      DOI: 10.1158/1078-0432.CCR-23-2654

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  45. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human lung cancer-derived mesenchymal stem cells promote tumor growth and immunosuppression
    1
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      VSV-G

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  46. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A CRISPRi/a screening platform to study cellular nutrient transport in diverse microenvironments
    1
    1. scibot 19 May 2024
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  47. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Monocyte to macrophage differentiation and changes in cellular redox homeostasis promote cell type-specific HIV latency reactivation
    1
    1. scibot 19 May 2024
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  48. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cell type specific long non-coding RNA targets identified by integrative analysis of single-cell and bulk colorectal cancer transcriptomes
    2
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  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Tumors cells with mismatch repair deficiency induce hyperactivation of pyroptosis resistant to cell membrane damage but are more sensitive to co-treatment of IFN-γ and TNF-α to PANoptosis
    1
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    OGT and OGA gene-edited human induced pluripotent stem cells for dissecting the functional roles of O-GlcNAcylation in hematopoiesis
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  51. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mecp2 fine-tunes quiescence exit by targeting nuclear receptors
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  52. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SETD2 Deficiency Confers Sensitivity to Dual Inhibition of DNA Methylation and PARP in Kidney Cancer
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  53. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A RAB7A phosphoswitch coordinates Rubicon Homology protein regulation of Parkin-dependent mitophagy
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  54. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting senescent cells with NKG2D-CAR T cells
    1
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  55. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Perinuclear damage from nuclear envelope deterioration elicits stress responses that contribute to LMNA cardiomyopathy
    1
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  56. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TruD technology for the study of epi- and endothelial tubes in vitro
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Network-based elucidation of colon cancer drug resistance mechanisms by phosphoproteomic time-series analysis
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  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Prolonged depletion of profilin 1 or F-actin causes an adaptive response in microtubules
    1
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  59. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    p53 modulates kinase inhibitor resistance and lineage plasticity in NF1-related MPNSTs
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  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    E4BP4 in macrophages induces an anti-inflammatory phenotype that ameliorates the severity of colitis
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  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal center cytokine driven epigenetic control of Epstein-Barr virus latency gene expression
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  62. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Role of the Senescence-Associated Factor Dipeptidyl Peptidase 4 in the Pathogenesis of SARS-CoV-2 Infection
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      plasmid_8454

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  63. 52.53.155.43 52.53.155.43
    Systemic Phospho-Defective and Phospho-Mimetic Drp1 Mice Exhibit Normal Growth and Development with Altered Anxiety-like Behavior
    1
    1. scibot 09 May 2024
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  64. www.sciencedirect.com www.sciencedirect.com
    FLT3L governs the development of partially overlapping hematopoietic lineages in humans and mice
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  65. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimisation of a primary human CAR‐NK cell manufacturing pipeline
    1
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      VSV‐G

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  66. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of tumor-derived SMAD4 enhances primary tumor growth but not metastasis following BMP4 signalling
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  67. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    RNA expression of 6 genes from metastatic mucosal gastric cancer serves as the global prognostic marker for gastric cancer with functional validation
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  68. www.sciencedirect.com www.sciencedirect.com
    Methylation of the chromatin modifier KMT2D by SMYD2 contributes to therapeutic response in hormone-dependent breast cancer
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  69. www.mdpi.com www.mdpi.com
    TurboID-Based IRE1 Interactome Reveals Participants of the Endoplasmic Reticulum-Associated Protein Degradation Machinery in the Human Mast Cell Leukemia Cell Line HMC-1.2
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  70. Apr 2024
  71. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Spatiotemporal binding of cyclophilin A and CPSF6 to capsid regulates HIV-1 nuclear entry and integration
    1
    1. scibot 30 Apr 2024
      pCMV-VSV-G

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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Classification and functional characterization of regulators of intracellular STING trafficking identified by genome-wide optical pooled screening
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    KIS counteracts PTBP2 and regulates alternative exon usage in neurons
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  74. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chromatin Remodeling in Patient‐Derived Colorectal Cancer Models
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  75. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Loss of NEDD8 in cancer cells causes vulnerability to immune checkpoint blockade in triple-negative breast cancer
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  76. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A vascularized breast cancer spheroid platform for the ranked evaluation of tumor microenvironment-targeted drugs by light sheet fluorescence microscopy
    1
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  77. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR/dCas9-Tet1-Mediated DNA Methylation Editing
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  78. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A disease-associated PPP2R3C-MAP3K1 phospho-regulatory module controls centrosome function
    1
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  79. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IQGAP3 Is an Important Mediator of Skin Inflammatory Diseases
    1
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  80. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HepG2BD: A Novel and Versatile Cell Line with Inducible HDV Replication and Constitutive HBV Expression
    1
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  81. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Residue K28 of Zika Virus NS5 Protein Is Implicated in Virus Replication and Antagonism of STAT2
    1
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  82. www.sciencedirect.com www.sciencedirect.com
    The Zn2+ transporter ZIP7 enhances endoplasmic-reticulum-associated protein degradation and prevents neurodegeneration in Drosophila
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  83. rupress.org rupress.org
    WW domains form a folded type of nuclear localization signal to guide YAP1 nuclear import
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  84. www.sciencedirect.com www.sciencedirect.com
    Integrated drug profiling and CRISPR screening identify BCR::ABL1-independent vulnerabilities in chronic myeloid leukemia
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  85. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of Four Mouse FcRn Splice Variants and FcRn-Specific Vesicles
    1
    1. scibot 23 Apr 2024
      pCMV-VSV-G

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A mechanism that transduces lysosomal damage signals to stress granule formation for cell survival
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    epHero – a tandem-fluorescent probe to track the fate of apoptotic cells during efferocytosis
    1
    1. scibot 23 Apr 2024
      plasmid_8454

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  88. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Context-dependent roles for ubiquitous mitochondrial creatine kinase CKMT1 in breast cancer progression
    1
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      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2024.114121

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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Krüppel-like Factor (KLF) family members control expression of genes required for serous cavity and alveolar macrophage identities
    1
    1. scibot 15 Apr 2024
      8454

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  90. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    O-GlcNAcylation of FOXK1 orchestrates the E2F pathway and promotes oncogenesis
    1
    1. scibot 15 Apr 2024
      8454

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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Calcium transients trigger switch-like discharge of prostaglandin E2 in an extracellular signal-regulated kinase-dependent manner
    1
    1. scibot 15 Apr 2024
      pCMV-VSV-G-RSV-Rev

      DOI: 10.7554/eLife.86727

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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The immunopathological landscape of human pre-TCRα deficiency: from rare to common variants
    1
    1. scibot 15 Apr 2024
      pCMV-VSV-G

      DOI: 10.1126/science.adh4059

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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Molecular basis promoting centriole triplet microtubule assembly
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      8454

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  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Centriole structural integrity defects are a crucial feature of Hydrolethalus Syndrome
    1
    1. scibot 15 Apr 2024
      plasmid_8454

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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial outer membrane integrity regulates a ubiquitin-dependent and NF-κB-mediated inflammatory response
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  96. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GNAQ/GNA11 Mosaicism Causes Aberrant Calcium Signaling Susceptible to Targeted Therapeutics
    1
    1. scibot 14 Apr 2024
      pCMV-VSVG

      DOI: 10.1016/j.jid.2023.08.028

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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting of vulnerabilities of drug-tolerant persisters identified through functional genetics delays tumor relapse
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      8454

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  98. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PARP2 promotes Break Induced Replication-mediated telomere fragility in response to replication stress
    1
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      8454

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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Orphan lysosomal solute carrier MFSD1 facilitates highly selective dipeptide transport
    1
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      8454

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Functional genetics reveals modulators of anti-microtubule drug sensitivity
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      Plasmid_8454

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  101. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PLD3 and PLD4 synthesize S,S-BMP, a key phospholipid enabling lipid degradation in lysosomes
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      Addgene_8454

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  102. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mesenchymal glioma stem cells trigger vasectasia—distinct neovascularization process stimulated by extracellular vesicles carrying EGFR
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      8454

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  103. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cooperative interaction of interferon regulatory factor -1 and bromodomain—containing protein 4 on RNA polymerase activation for intrinsic innate immunity
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      8454

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  104. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-genome analysis reveals a heterogeneous association of the herpes simplex virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
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      RRID:Addgene_8454

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  105. www.sciencedirect.com www.sciencedirect.com
    Genetic interactions reveal distinct biological and therapeutic implications in breast cancer
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    1. scibot 09 Apr 2024
      AddgeneCat# 8454

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    sciencedirect.com/science/article/pii/S1535610824000916
  106. www.sciencedirect.com www.sciencedirect.com
    Spastin locally amplifies microtubule dynamics to pattern the axon for presynaptic cargo delivery
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      AddgeneCat# #8454

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a novel prostate Cancer-Stroma Sphere (CSS) model for In Vitro tumor microenvironment studies
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      8454

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  108. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Role of HIV-1-Encoded microRNAs in Viral Replication
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    1. scibot 01 Apr 2024
      plasmid_8454

      DOI: 10.3390/microorganisms12030425

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DEAD box RNA helicase 5 is a new pro-viral host factor for Sindbis virus infection
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  110. Mar 2024
  111. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitochondrial Ribosomal Protein MRPS15 Is a Component of Cytosolic Ribosomes and Regulates Translation in Stressed Cardiomyocytes
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    1. scibot 31 Mar 2024
      pCMV-VSV-G

      DOI: 10.3390/ijms25063250

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  112. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PIP4K2B Protein Regulation by NSD1 in HPV-Negative Head and Neck Squamous Cell Carcinoma
    1
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      8454

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  113. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Actin-Dependent Mechanism of Tumor Progression Induced by a Dysfunction of p53 Tumor Suppressor
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    1. scibot 31 Mar 2024
      8454

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  114. www.sciencedirect.com www.sciencedirect.com
    Initiation of a ZAKα-dependent ribotoxic stress response by the innate immunity endoribonuclease RNase L
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    1. scibot 29 Mar 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2024.113998

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    sciencedirect.com/science/article/pii/S2211124724003267
  115. www.sciencedirect.com www.sciencedirect.com
    RPGR is a guanine nucleotide exchange factor for the small GTPase RAB37 required for retinal function via autophagy regulation
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    1. scibot 28 Mar 2024
      8454; Addgene

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    sciencedirect.com/science/article/pii/S2211124724003383
  116. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc Alpha-2-Glycoprotein (ZAG/AZGP1) secreted by triple-negative breast cancer promotes tumor microenvironment fibrosis
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      RRID:Addgene_8454

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  117. link.springer.com link.springer.com
    Depletion of lamins B1 and B2 promotes chromatin mobility and induces differential gene expression by a mesoscale-motion-dependent mechanism
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    1. scibot 26 Mar 2024
      plasmid_8454

      DOI: 10.1186/s13059-024-03212-y

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  118. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ΔNp63 regulates MDSC survival and metabolism in triple-negative breast cancer
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      RRID:Addgene_8454

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  119. www.sciencedirect.com www.sciencedirect.com
    FAM86A methylation of eEF2 links mRNA translation elongation to tumorigenesis
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      Addgene_8454

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  120. www.biorxiv.org www.biorxiv.org
    Formamide denaturation of double-stranded DNA for fluorescence in situ hybridization (FISH) distorts nanoscale chromatin structure
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    1. scibot 21 Mar 2024
      plasmid_8454

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone H3.1 is a chromatin-embedded redox sensor triggered by tumor cells developing adaptive phenotypic plasticity and multidrug resistance
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      RRID:Addgene_8454

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  122. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Aryl hydrocarbon receptor suppresses STING-mediated type I IFN expression in triple-negative breast cancer
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      pCMV-VSV-G

      DOI: 10.1038/s41598-024-54732-3

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  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Metformin reduces the clonal fitness of Dnmt3aR878H hematopoietic stem and progenitor cells by reversing their aberrant metabolic and epigenetic state
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    1. scibot 17 Mar 2024
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      DOI: 10.21203/rs.3.rs-3874821/v1

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  124. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Efficient and scalable gene delivery method with easily generated cationic carbon dots
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      8454

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  125. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Optimized protocol for CRISPR knockout of human iPSC-derived macrophages
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      8454

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  126. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Repeat DNA methylation is modulated by adherens junction signaling
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      8454

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  127. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The neuronal transcription factor MEIS2 is a calpain2 protease target
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  128. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induction of Multiple Alternative Mitogenic Signaling Pathways Accompanies the Emergence of Drug-Tolerant Cancer Cells
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  129. www.biorxiv.org www.biorxiv.org
    Combinatorial in vivo genome editing identifies widespread epistasis during lung tumorigenesis
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  130. www.sciencedirect.com www.sciencedirect.com
    CDK-independent role of D-type cyclins in regulating DNA mismatch repair
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      Plasmid #8454

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  131. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The helicase domain of human Dicer prevents RNAi-independent activation of antiviral and inflammatory pathways
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  132. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    FH variant pathogenicity promotes purine salvage pathway dependence in kidney cancer
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      DOI: 10.1158/2159-8290.CD-22-0874

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    ncbi.nlm.nih.gov/pmc/articles/PMC10527600/
  133. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene editing-based targeted integration for correction of Wiskott-Aldrich syndrome
    1
    1. scibot 02 Mar 2024
      pCMV-VSV-G

      DOI: 10.1016/j.omtm.2024.101208

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897892/
  134. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Programmable RNA writing with trans-splicing
    1
    1. scibot 02 Mar 2024
      Addgene_8454

      DOI: 10.1101/2024.01.31.578223

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    ncbi.nlm.nih.gov/pmc/articles/PMC10862893/
  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Disease-associated polyalanine expansion mutations impair UBA6-dependent ubiquitination
    1
    1. scibot 01 Mar 2024
      pCMV-VSVG

      DOI: 10.1038/s44318-023-00018-9

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    ncbi.nlm.nih.gov/pmc/articles/PMC10897158/
  136. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A methylation-phosphorylation switch controls EZH2 stability and hematopoiesis
    1
    1. scibot 01 Mar 2024
      8454

      DOI: 10.7554/eLife.86168

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    ncbi.nlm.nih.gov/pmc/articles/PMC10901513/
  137. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integration of transcription regulation and functional genomic data reveals lncRNA SNHG6’s role in hematopoietic differentiation and leukemia
    1
    1. scibot 01 Mar 2024
      plasmid_8454

      DOI: 10.1186/s12929-024-01015-8

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    ncbi.nlm.nih.gov/pmc/articles/PMC10900714/
  138. Feb 2024
  139. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The membrane-associated ubiquitin ligase MARCHF8 stabilizes the human papillomavirus oncoprotein E7 by degrading CUL1 and UBE2L3 in head and neck cancer
    1
    1. scibot 29 Feb 2024
      8454

      DOI: 10.1128/jvi.01726-23

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878100/
  140. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SARS-CoV-2 and oncolytic EV-D68-encoded proteases differentially regulate pyroptosis
    1
    1. scibot 29 Feb 2024
      8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878271/
  141. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POZ/BTB and AT hook containing zinc finger 1 (PATZ1) suppresses differentiation and regulates metabolism in human embryonic stem cells
    1
    1. scibot 29 Feb 2024
      VSVG

      DOI: 10.7150/ijbs.83927

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    ncbi.nlm.nih.gov/pmc/articles/PMC10878140/
  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Agent-based modeling of the prostate tumor microenvironment uncovers spatial tumor growth constraints and immunomodulatory properties
    1
    1. scibot 29 Feb 2024
      pCMV-VSV-G

      DOI: 10.1038/s41540-024-00344-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881528/
  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Open-source milligram-scale, four channel, automated protein purification system
    1
    1. scibot 29 Feb 2024
      8454

      DOI: 10.1371/journal.pone.0297879

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889886/
  144. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Plasticity-induced repression of Irf6 underlies acquired resistance to cancer immunotherapy in pancreatic ductal adenocarcinoma
    1
    1. scibot 29 Feb 2024
      plasmid_8454

      DOI: 10.1038/s41467-024-46048-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10879147/
  145. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Quantitative MRI Evaluation of Ferritin Overexpression in Non-Small-Cell Lung Cancer
    1
    1. scibot 28 Feb 2024
      pCMV-VSV-G

      DOI: 10.3390/ijms25042398

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    ncbi.nlm.nih.gov/pmc/articles/PMC10889593/
  146. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DMT1-dependent endosome-mitochondria interactions regulate mitochondrial iron translocation and metastatic outgrowth
    1
    1. scibot 28 Feb 2024
      pCMV-VSV-G

      DOI: 10.1038/s41388-023-02933-x

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    ncbi.nlm.nih.gov/pmc/articles/PMC10890933/
  147. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DUX4-r exerts a neomorphic activity that depends on GTF2I in acute lymphoblastic leukemia
    1
    1. scibot 28 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1126/sciadv.adi3771

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    ncbi.nlm.nih.gov/pmc/articles/PMC10881058/
  148. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    IMPDH2 filaments protect from neurodegeneration in AMPD2 deficiency
    1
    1. scibot 16 Feb 2024
      8454

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    ncbi.nlm.nih.gov/pmc/articles/PMC10849482/
  149. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Extracellular Proximity Labeling Reveals an Expanded Interactome for the Matrisome Protein TIMP2
    1
    1. scibot 16 Feb 2024
      plasmid_8454

      DOI: 10.21203/rs.3.rs-3857263/v1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10836090/
  150. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NSD1 supports cell growth and regulates autophagy in HPV-negative head and neck squamous cell carcinoma
    1
    1. scibot 15 Feb 2024
      8454

      DOI: 10.1038/s41420-024-01842-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10861597/
  151. www.sciencedirect.com www.sciencedirect.com
    Protocol for organelle-specific cysteine capture and quantification of cysteine oxidation state
    1
    1. scibot 15 Feb 2024
      Addgene_8454

      DOI: 10.1016/j.xpro.2024.102865

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    sciencedirect.com/science/article/pii/S2666166724000303
  152. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcription-Coupled Repair of DNA Interstrand Crosslinks by UVSSA
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1101/2023.05.10.538304

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    ncbi.nlm.nih.gov/pmc/articles/PMC10197625/
  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characterization of dabrafenib-induced drug insensitivity via cellular barcoding and collateral sensitivity to second-line therapeutics
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1038/s41598-023-50443-3

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    ncbi.nlm.nih.gov/pmc/articles/PMC10762103/
  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    USP54 is a potential therapeutic target in castration-resistant prostate cancer
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1186/s12894-024-01418-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10845770/
  155. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Three-step docking by WIPI2, ATG16L1, and ATG3 delivers LC3 to the phagophore
    1
    1. scibot 13 Feb 2024
      8454

      DOI: 10.1126/sciadv.adj8027

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    ncbi.nlm.nih.gov/pmc/articles/PMC10851258/
  156. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated multi-omics analyses identify anti-viral host factors and pathways controlling SARS-CoV-2 infection
    1
    1. scibot 08 Feb 2024
      8454

      DOI: 10.1038/s41467-023-44175-1

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    ncbi.nlm.nih.gov/pmc/articles/PMC10761986/
  157. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mitofusin 1 silencing decreases the senescent associated secretory phenotype, promotes immune cell recruitment and delays melanoma tumor growth after chemotherapy
    1
    1. scibot 08 Feb 2024
      8454

      DOI: 10.1038/s41598-024-51427-7

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    ncbi.nlm.nih.gov/pmc/articles/PMC10776601/
  158. www.sciencedirect.com www.sciencedirect.com
    Pharmacological inhibition of neddylation impairs long interspersed element 1 retrotransposition
    1
    1. scibot 08 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2024.113749

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    sciencedirect.com/science/article/pii/S2211124724000779
  159. link.springer.com link.springer.com
    Effect of Octamer-Binding Transcription Factor 4 Overexpression on the Neural Induction of Human Dental Pulp Stem Cells
    1
    1. scibot 07 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1007/s12015-024-10678-7

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    link.springer.com/article/10.1007/s12015-024-10678-7
  160. www.sciencedirect.com www.sciencedirect.com
    One-pot DTECT enables rapid and efficient capture of genetic signatures for precision genome editing and clinical diagnostics
    1
    1. scibot 07 Feb 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.crmeth.2024.100698

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    sciencedirect.com/science/article/pii/S2667237524000043
  161. www.sciencedirect.com www.sciencedirect.com
    Direct reprogramming of non-limb fibroblasts to cells with properties of limb progenitors
    1
    1. scibot 06 Feb 2024
      Addgene_8454

      DOI: 10.1016/j.devcel.2023.12.010

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    sciencedirect.com/science/article/pii/S1534580723006901
  162. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Micronucleus is not a potent inducer of the cGAS/STING pathway
    1
    1. scibot 05 Feb 2024
      8454

      DOI: 10.26508/lsa.202302424

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    ncbi.nlm.nih.gov/pmc/articles/PMC10837050/
  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Germinal Center Cytokines Driven Epigenetic Control of Epstein-Barr Virus Latency Gene Expression
    1
    1. scibot 05 Feb 2024
      plasmid_8454

      DOI: 10.1101/2024.01.02.573986

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802360/
  164. www.sciencedirect.com www.sciencedirect.com
    PNMA2 forms immunogenic non-enveloped virus-like capsids associated with paraneoplastic neurological syndrome
    1
    1. scibot 02 Feb 2024
      RRID: Addgene_8454

      DOI: 10.1016/j.cell.2024.01.009

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    sciencedirect.com/science/article/pii/S0092867424000114
  165. www.sciencedirect.com www.sciencedirect.com
    CAG repeat expansions create splicing acceptor sites and produce aberrant repeat-containing RNAs
    1
    1. scibot 02 Feb 2024
      plasmid_8454

      DOI: 10.1016/j.molcel.2024.01.006

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    sciencedirect.com/science/article/pii/S1097276524000078
  166. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    K-Ras(V12) differentially affects the three Akt isoforms in lung and pancreatic carcinoma cells and upregulates E-cadherin and NCAM via Akt3
    1
    1. scibot 01 Feb 2024
      pCMV-VSV-G

      DOI: 10.1186/s12964-024-01484-2

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    ncbi.nlm.nih.gov/pmc/articles/PMC10826106/
  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    MRE11 liberates cGAS from nucleosome sequestration during tumorigenesis
    1
    1. scibot 01 Feb 2024
      8454

      DOI: 10.1038/s41586-023-06889-6

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    ncbi.nlm.nih.gov/pmc/articles/PMC10794148/
  168. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Charting Single Cell Lineage Dynamics and Mutation Networks via Homing CRISPR
    1
    1. scibot 01 Feb 2024
      8454

      DOI: 10.1101/2024.01.05.574236

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802354/
  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Gene engineered exosome reverses T cell exhaustion in cancer immunotherapy
    1
    1. scibot 01 Feb 2024
      plasmid_8454

      DOI: 10.1016/j.bioactmat.2024.01.008

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    ncbi.nlm.nih.gov/pmc/articles/PMC10825617/
  170. Jan 2024
  171. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    PD-1 signaling uncovers a pathogenic subset of T cells in inflammatory arthritis
    1
    1. scibot 30 Jan 2024
      AddGene 8454

      DOI: 10.1186/s13075-023-03259-5

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    ncbi.nlm.nih.gov/pmc/articles/PMC10801937/
  172. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hydroxynorketamine, but not ketamine, acts via α7 nicotinic acetylcholine receptor to control presynaptic function and gene expression
    1
    1. scibot 30 Jan 2024
      #8454, Addgene

      DOI: 10.1038/s41398-024-02744-y

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    ncbi.nlm.nih.gov/pmc/articles/PMC10803733/
  173. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Involvement of Protease-Activated Receptor2 Pleckstrin Homology Binding Domain in Ovarian Cancer: Expression in Fallopian Tubes and Drug Design
    1
    1. scibot 30 Jan 2024
      8454

      DOI: 10.3390/biomedicines12010246

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    ncbi.nlm.nih.gov/pmc/articles/PMC10813316/
  174. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonsynonymous Mutations in Intellectual Disability and Autism Spectrum Disorder Gene PTCHD1 Disrupt N-Glycosylation and Reduce Protein Stability
    1
    1. scibot 29 Jan 2024
      #8454; Addgene

      DOI: 10.3390/cells13020199

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    ncbi.nlm.nih.gov/pmc/articles/PMC10814814/
  175. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    D-type cyclins regulate DNA mismatch repair in the G1 and S phases of the cell cycle, maintaining genome stability
    1
    1. scibot 29 Jan 2024
      Plasmid_8454

      DOI: 10.1101/2024.01.12.575420

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    ncbi.nlm.nih.gov/pmc/articles/PMC10802603/
  176. www.sciencedirect.com www.sciencedirect.com
    Massively parallel disruption of enhancers active in human neural stem cells
    2
    1. scibot 25 Jan 2024
      Plasmid_8454

      DOI: 10.1016/j.celrep.2024.113693

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      Plasmid_8454

      DOI: 10.1016/j.celrep.2024.113693

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    sciencedirect.com/science/article/pii/S2211124724000214
  177. www.sciencedirect.com www.sciencedirect.com
    Cholinergic signaling via muscarinic M1 receptor confers resistance to docetaxel in prostate cancer
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    1. scibot 23 Jan 2024
      RRID: Addgene_8454

      DOI: 10.1016/j.xcrm.2023.101388

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    sciencedirect.com/science/article/pii/S2666379123006171
  178. www.science.org www.science.org
    Astrocytic TDP-43 dysregulation impairs memory by modulating antiviral pathways and interferon-inducible chemokines
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    1. scibot 18 Jan 2024
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      DOI: 10.1126/sciadv.ade1282

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    science.org/doi/10.1126/sciadv.ade1282
  179. www.sciencedirect.com www.sciencedirect.com
    Nuclear phosphoproteome reveals Prolyl Isomerase PIN1 as a modulator of oncogene-induced senescence.
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    1. scibot 18 Jan 2024
      RRID:Addgene_8454

      DOI: 10.1016/j.mcpro.2024.100715

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    sciencedirect.com/science/article/pii/S1535947624000057
  180. dx.doi.org dx.doi.org
    Kaposi's sarcoma herpesvirus exploits the DNA damage response to circularize its genome
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    1. scibot 10 Jan 2024
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      DOI: 10.1093/nar/gkad1224

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    dx.doi.org/10.1093/nar/gkad1224
  181. Dec 2023
  182. www.sciencedirect.com www.sciencedirect.com
    An ERK5-PFKFB3 axis regulates glycolysis and represents a therapeutic vulnerability in pediatric diffuse midline glioma
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    1. scibot 23 Dec 2023
      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2023.113557

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    sciencedirect.com/science/article/pii/S2211124723015693
  183. www.sciencedirect.com www.sciencedirect.com
    Non-canonical Hedgehog signaling mediates profibrotic hematopoiesis-stroma crosstalk in myeloproliferative neoplasms
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    1. scibot 22 Dec 2023
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  184. www.sciencedirect.com www.sciencedirect.com
    KDM5B predicts temozolomide-resistant subclones in glioblastoma
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    1. scibot 20 Dec 2023
      RRID: Addgene_8454

      DOI: 10.1016/j.isci.2023.108596

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    sciencedirect.com/science/article/pii/S2589004223026731
  185. www.sciencedirect.com www.sciencedirect.com
    The MHC-E peptide ligands for checkpoint CD94/NKG2A are governed by inflammatory signals, whereas LILRB1/2 receptors are peptide indifferent
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    1. scibot 20 Dec 2023
      Addgene Cat: 8454

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    sciencedirect.com/science/article/pii/S2211124723015280
  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-genome analysis reveals heterogeneous association of the Herpes Simplex Virus genome with H3K27me2 and the reader PHF20L1 following infection of human fibroblasts
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      RRID:Addgene_8454

      DOI: 10.1101/2023.12.03.569766

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    ncbi.nlm.nih.gov/pmc/articles/PMC10705572/
  187. www.sciencedirect.com www.sciencedirect.com
    Profiling nuclear cysteine ligandability and effects on nuclear localization using proximity labeling-coupled chemoproteomics
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    sciencedirect.com/science/article/pii/S2451945623004257
  188. 52.53.155.43 52.53.155.43
    978-1-0716-3593-3-html.html
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    52.53.155.43/13e95334a348a589bd777c46a75603c23c56efd2/978-1-0716-3593-3-html.html
  189. link.springer.com link.springer.com
    Rational optimization of a transcription factor activation domain inhibitor
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    1. scibot 08 Dec 2023
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      DOI: 10.1038/s41594-023-01159-5

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  190. Nov 2023
  191. www.sciencedirect.com www.sciencedirect.com
    The RNA helicase DDX39A binds a conserved structure in chikungunya virus RNA to control infection
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    1. scibot 28 Nov 2023
      RRID:Addgene_8454

      DOI: 10.1016/j.molcel.2023.10.008

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    sciencedirect.com/science/article/pii/S1097276523008420
  192. www.sciencedirect.com www.sciencedirect.com
    A combinatorial therapeutic approach to enhance FLT3-ITD AML treatment
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    1. scibot 28 Nov 2023
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    sciencedirect.com/science/article/pii/S2666379123004809
  193. www.sciencedirect.com www.sciencedirect.com
    Differences in syncytia formation by SARS-CoV-2 variants modify host chromatin accessibility and cellular senescence via TP53
    3
    1. scibot 22 Nov 2023
      Addgene #8454

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    sciencedirect.com/science/article/pii/S2211124723014900
  194. www.sciencedirect.com www.sciencedirect.com
    Aryl Hydrocarbon Receptor is a Tumor Promoter in MYCN-Amplified Neuroblastoma Cells Through Suppression of Differentiation
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    1. scibot 18 Nov 2023
      Plasmid_8454

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    sciencedirect.com/science/article/pii/S2589004223023805
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Convergent activation of two-pore channels mediated by the NAADP-binding proteins JPT2 and LSM12
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    1. scibot 15 Nov 2023
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      DOI: 10.1126/scisignal.adg0485

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    ncbi.nlm.nih.gov/pmc/articles/PMC10639087/
  196. www.sciencedirect.com www.sciencedirect.com
    Gasdermin D permeabilization of mitochondrial inner and outer membranes accelerates and enhances pyroptosis
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    1. scibot 10 Nov 2023
      RRID:Addgene_8454

      DOI: 10.1016/j.immuni.2023.10.004

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    sciencedirect.com/science/article/pii/S1074761323004442
  197. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuronal activation of Gαq EGL-30/GNAQ late in life rejuvenates cognition across species
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    1. scibot 09 Nov 2023
      RRID:Addgene_8454

      DOI: 10.1016/j.celrep.2023.113151

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    ncbi.nlm.nih.gov/pmc/articles/PMC10627507/
  198. www.sciencedirect.com www.sciencedirect.com
    Chimeric autoantibody receptor T cells deplete NMDA receptor-specific B cells
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    1. scibot 03 Nov 2023
      plasmid_8454

      DOI: 10.1016/j.cell.2023.10.001

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    sciencedirect.com/science/article/pii/S0092867423010838
  199. www.sciencedirect.com www.sciencedirect.com
    CRISPR/Cas9 screens unravel miR-3689a-3p regulating sorafenib resistance in hepatocellular carcinoma via suppressing CCS/SOD1-dependent mitochondrial oxidative stress
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    1. scibot 02 Nov 2023
      RRID:Addgene_8454

      DOI: 10.1016/j.drup.2023.101015

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    sciencedirect.com/science/article/pii/S1368764623000985
  200. Oct 2023
  201. link.springer.com link.springer.com
    A dual sgRNA library design to probe genetic modifiers using genome-wide CRISPRi screens
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    1. scibot 31 Oct 2023
      RRID:Addgene_8454

      DOI: 10.1186/s12864-023-09754-y

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    link.springer.com/article/10.1186/s12864-023-09754-y
  202. www.sciencedirect.com www.sciencedirect.com
    CD36 maintains lipid homeostasis via selective uptake of monounsaturated fatty acids during matrix detachment and tumor progression
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    sciencedirect.com/science/article/pii/S1550413123003686
  203. www.biorxiv.org www.biorxiv.org
    Dicer deficiency in microglia leads to accelerated demyelination and failed remyelination
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    1. scibot 27 Oct 2023
      RRID:Addgene_8454

      DOI: 10.1101/2023.10.17.562812

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    biorxiv.org/content/10.1101/2023.10.17.562812v1
  204. www.biorxiv.org www.biorxiv.org
    Genome-wide CRISPR/Cas9 screen identifies MAT2A as a critical host factor for BK Polyomavirus
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    1. scibot 27 Oct 2023
      RRID:Addgene_8454

      DOI: 10.1101/2023.10.20.563362

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    biorxiv.org/content/10.1101/2023.10.20.563362v1