1,106 Matching Annotations
  1. Last 7 days
  2. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    TRPV1 Downregulation Impairs Prostate Cancer Growth: Functional and Translational Insights from Cellular and In Vivo Models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12905635/
  3. Feb 2026
  4. www.sciencedirect.com www.sciencedirect.com
    SNAP25 undergoes phase separation to facilitate the assembly of the synaptic vesicle fusion machinery
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    sciencedirect.com/science/article/pii/S2211124726000616
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    Protocol for non-invasive delivery of CRISPR RNPs via virus-like particles for mouse model generation
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    sciencedirect.com/science/article/pii/S2666166726000055
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    Photosensitizer proximity labeling captures the lipid and protein interactomes
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    nature.com/articles/s41589-026-02140-1
  7. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mutations in VPS18 lead to a neutrophil maturation defect associated with disturbed vesicle homeostasis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12876832/
  8. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying targeted therapies for CBFA2T3::GLIS2 acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12875880/
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    The SWI/SNF-related protein SMARCA3 is a histone H3K23 ubiquitin ligase that regulates H3K9me3 in cancer
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    sciencedirect.com/science/article/pii/S1097276525005507
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    Bmp9 regulates Notch signaling and the temporal dynamics of angiogenesis via Lunatic Fringe
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    sciencedirect.com/science/article/pii/S1534580726000298
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    Mechanosensation promotes broad-spectrum antiviral defense through membrane remodeling
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    sciencedirect.com/science/article/pii/S2451945626000243
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    NAD+ sensing by PARP7 regulates the C/EBPβ-dependent transcription program during adipogenesis
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    sciencedirect.com/science/article/pii/S2211124726000070
  13. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A kinome inhibitor screen implicates adhesion and growth factor signaling in cellular recovery after caspase activation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12803139/
  14. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pancreatic Cancer Stem Cells Co-Expressing SOX2, OCT4, and TERThigh Represent an Aggressive Subpopulation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12839176/
  15. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Bromhexine inhibits SARS-CoV-2 Omicron and variant pseudovirus infection via ACE2-targeted mechanisms
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    pmc.ncbi.nlm.nih.gov/articles/PMC12832721/
  16. Jan 2026
  17. pubs.acs.org pubs.acs.org
    Indocyanine Green-Labeled Antibodies Cotargeting CDCP1 and Mesothelin for Fluorescence-Guided Imaging of Pancreatic Cancer
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    pubs.acs.org/doi/full/10.1021/acs.molpharmaceut.5c01452
  18. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12747521/
  19. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Hypoxic conditions confer chemoresistance to crizotinib but not to imatinib in chronic myeloid leukemia cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12818218/
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    Human genetics guides the discovery of CARD9 inhibitors with anti-inflammatory activity
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    sciencedirect.com/science/article/pii/S0092867425014266
  21. 54.241.53.176 54.241.53.176
    sechrist-et-al-2026-ablation-of-tumor-derived-igfbp-3-attenuates-cancer-associated-skeletal-muscle-wasting-in-murine-html.html
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    Actin dysregulation induces neuroendocrine plasticity and immune evasion: a vulnerability of small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12795832/
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    Decreased Kinase Activity of the VEGFR3 Variant c.3175G>C Associated with Primary Lymphedema
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    mdpi.com/1467-3045/48/1/68
  24. www.biorxiv.org www.biorxiv.org
    MYST acetyltransferases are a targetable therapeutic vulnerability in SETBP1-mutant leukemia
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    biorxiv.org/content/10.64898/2026.01.08.697228v1
  25. elifesciences.org elifesciences.org
    Decoding the biogenesis of HIV-induced CPSF6 puncta and their fusion with nuclear speckles
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    elifesciences.org/articles/103725
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    A CLOCK-targeting lncRNA induces trained immunity against tuberculosis
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    sciencedirect.com/science/article/pii/S1931312825005219
  27. Dec 2025
  28. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Mitochondrial VHL rewires cell metabolism in hypoxia
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    sciencedirect.com:5037/science/article/pii/S1550413125005273
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    Cell-surface RNA forms ternary complex with RNA-binding proteins and heparan sulfate to recruit immune receptors
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    sciencedirect.com:5037/science/article/pii/S1097276525009372
  30. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Ultrastructural membrane dynamics of mouse and human cortical synapses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12703363/
  31. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
    FEBS Press
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    febs.onlinelibrary.wiley.com/doi/full/10.1111/febs.70360
  32. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional differences between CLL‐ and ALL‐derived CAR T cells in a 3D tumor microenvironment highlight CXCR4 and IL‐10 as potential modulatory targets
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    pmc.ncbi.nlm.nih.gov/articles/PMC12683941/
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    Context-dependent inhibitory roles of RhoA in 3D invasive cell migration within the extracellular matrix
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    sciencedirect.com:5037/science/article/pii/S2211124725014214
  34. www.biorxiv.org www.biorxiv.org
    Reactivation of the X-linked Nexmif Gene Corrects Mosaic NEXMIF Deficiency in Heterozygous Female Mice
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    biorxiv.org/content/10.1101/2025.11.29.691251v1
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    KSR1 mediates small-cell lung carcinoma tumor initiation and cisplatin resistance
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    pmc.ncbi.nlm.nih.gov/articles/PMC12133430/
  36. link.springer.com link.springer.com
    Lenacapavir-induced capsid damage uncovers HIV-1 genomes emanating from nuclear speckles
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    link.springer.com/article/10.1038/s44318-025-00652-5
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    Interleukin-1/Toll-like receptor signaling potentiates macrophage olfactory receptor 2-driven atherosclerosis
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    sciencedirect.com:5037/science/article/pii/S2211124725014111
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    Cadherin-1-mediated communication at the leader-follower boundary controls mouse breast tumor organoid collective migration
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    sciencedirect.com:5037/science/article/pii/S2211124725014032
  39. Nov 2025
  40. www.sciencedirect.com:5037 www.sciencedirect.com:5037
    Potentiation of noncanonical NF-κB signaling and marginal zone B cell expansion by CARD11-mediated regulation of p100 processing
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    sciencedirect.com:5037/science/article/pii/S2211124725013889
  41. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A distal promoter and aberrant splicing enable canonical translation of out-of-frame proteins in Huntington’s disease
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    pmc.ncbi.nlm.nih.gov/articles/PMC12633298/
  42. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Detection of biogenic magnetic nanoparticles in rapidly dividing tumor cells by the nonlinear magnetization method
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    pmc.ncbi.nlm.nih.gov/articles/PMC12598001/
  43. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Histone deacetylase 7 mediates lipopolysaccharide-inducible mitochondrial fission in macrophages
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    pmc.ncbi.nlm.nih.gov/articles/PMC12539210/
  44. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Prostaglandin E2 inhibits adipogenesis through the cilia-dependent activation of ROCK2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582440/
  45. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Systematic discovery of subcellular RNA patterns in the gut epithelium
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  46. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered virus-like particle-assembled Vegfa-targeting Cas9 ribonucleoprotein treatment alleviates neovascularization in wet age-related macular degeneration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12509411/
  47. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    A CRISPR activation screen reveals a cilia disassembly pathway mutated in focal cortical dysplasia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571082/
  48. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Aging represses oncogenic KRAS-driven lung tumorigenesis and alters tumor suppression
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616358/
  49. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pyroglutamation of cell surface proteins CD47 and TRP1 by glutaminyl cyclase modulates therapeutic antibody binding
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    pmc.ncbi.nlm.nih.gov/articles/PMC12615796/
  50. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Identifying TP53RK as a key regulator of colorectal cancer survival and a potential therapeutic target
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    pmc.ncbi.nlm.nih.gov/articles/PMC12533122/
  51. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Pathogenic UNC13A variants cause a neurodevelopmental syndrome by impairing synaptic function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12597829/
  52. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    L-Dopa-modified microtubules lead to synapse instability in cultured neurons: possible implications in Parkinson’s disease therapy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12534460/
  53. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Engineered CXCR3-A expression enhances B7-H3-targeting CAR T cell migration and efficacy against diffuse intrinsic pontine glioma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12606338/
  54. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Cellular activity upregulation of the thermolabile p53 cancer mutant Y220C by small molecule indazole derivatives
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    pmc.ncbi.nlm.nih.gov/articles/PMC12594860/
  55. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Deacetylation of TALDO1 by HDAC6 promotes glycolysis and nasopharyngeal carcinoma progression through a moonlighting function
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    pmc.ncbi.nlm.nih.gov/articles/PMC12540763/
  56. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    CD16A Shedding Regulates Innate Cell Engager‐Induced Serial Killing by Natural Killer Cells
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    pmc.ncbi.nlm.nih.gov/articles/PMC12537995/
  57. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Conformation of HLA-E/peptide complex guides interaction with two novel HLA-E receptors: Stabilin 1 and 2
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    pmc.ncbi.nlm.nih.gov/articles/PMC12517498/
  58. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    RNA binding of GAPDH controls transcript stability and protein translation in acute myeloid leukemia
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    pmc.ncbi.nlm.nih.gov/articles/PMC12582121/
  59. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Lysine-specific histone demethylase complex restricts Epstein-Barr virus lytic reactivation
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    pmc.ncbi.nlm.nih.gov/articles/PMC12616731/
  60. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Large transient assemblies of Apaf1 constitute the apoptosome in cells
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  61. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    ZEB1, a novel junctional adhesion molecule A regulator, impacts sensitivity of pancreatic cancer-associated fibroblasts to reovirus
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    pmc.ncbi.nlm.nih.gov/articles/PMC12617759/
  62. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Multimodal Detection of Magnetically and Fluorescently Dual-Labeled Murine Macrophages After Intravenous Administration
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    pmc.ncbi.nlm.nih.gov/articles/PMC12472669/
  63. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Single-round infectious rotaviruses with deletions of VP7 or VP4 genes, based on SA11 and WC3 strain backbones, and their potential use as viral vectors
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    pmc.ncbi.nlm.nih.gov/articles/PMC12435675/
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    Generation of hTERT-immortalized human mesenchymal stromal cells with optical and magnetic labels for in vivo transplantation and tracking
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    pmc.ncbi.nlm.nih.gov/articles/PMC12619327/
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    Optimizing the in vitro neuronal microenvironment to mitigate phototoxicity in live-cell imaging
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    pmc.ncbi.nlm.nih.gov/articles/PMC12465337/
  66. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Differential regulation of mesoscale chromosome conformations in osteoblasts and osteosarcoma
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    pmc.ncbi.nlm.nih.gov/articles/PMC12465978/
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    Dual targeting of CDK4/6 and CDK7 augments tumor response and antitumor immunity in breast cancer models
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    pmc.ncbi.nlm.nih.gov/articles/PMC12520673/
  68. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Autocrine Fibroblast Growth Factor Receptor 1 Signaling Activates Lactate Dehydrogenase A-Aerobic Glycolysis for Advanced Human Prostate Tumor Growth
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    pmc.ncbi.nlm.nih.gov/articles/PMC12457063/
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    Pseudorabies virus induces ferroptosis by disrupting iron homeostasis through activation of TfR1 and ferritinophagy
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    pmc.ncbi.nlm.nih.gov/articles/PMC12456129/
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    Bi-handed assembly chaperones regulate protein complex assembly through an intramolecular handover mechanism
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  71. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Morphine regulates astrocyte transcriptional dynamics in the ventral tegmental area by stimulation of glucocorticoid signaling
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    pmc.ncbi.nlm.nih.gov/articles/PMC12485804/
  72. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Nanoscopy Reveals Heparan Sulfate Clusters as Docking Sites for SARS-CoV-2 Attachment and Entry
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    pmc.ncbi.nlm.nih.gov/articles/PMC12439973/
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    In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
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    pmc.ncbi.nlm.nih.gov/articles/PMC11974748/
  74. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Mammalian ZAP and KHNYN can independently restrict CpG-enriched avian viruses
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    pmc.ncbi.nlm.nih.gov/articles/PMC11703154/
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    Therapeutic benefits of maintaining CDK4/6 inhibitors and incorporating CDK2 inhibitors beyond progression in breast cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC11601343/
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    IRS2 as a driver of brain metastasis in colorectal cancer: A potential target for novel therapeutic strategies
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    pmc.ncbi.nlm.nih.gov/articles/PMC12417839/
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    Human CD4+ T cells recognize Mycobacterium tuberculosis–infected macrophages amid broader responses
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    pmc.ncbi.nlm.nih.gov/articles/PMC12459340/
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    In situ cryo-ET visualization of mitochondrial depolarization and mitophagic engulfment
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    pmc.ncbi.nlm.nih.gov/articles/PMC12337332/
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    Fructose and glucose from sugary drinks enhance colorectal cancer metastasis via SORD
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    pmc.ncbi.nlm.nih.gov/articles/PMC12552132/
  80. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Genetic and epigenetic screens in primary human T cells link candidate causal autoimmune variants to T cell networks
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    pmc.ncbi.nlm.nih.gov/articles/PMC12513834/
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    Reprogramming neuroblastoma by diet-enhanced polyamine depletion
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527938/
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    Basal cell of origin resolves neuroendocrine–tuft lineage plasticity in cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12589105/
  83. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Functional synapses between neurons and small cell lung cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12571904/
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    Membrane receptors cluster phosphatidylserine to activate LC3-associated phagocytosis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12527911/
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    Durotaxis is a driver and potential therapeutic target in lung fibrosis and metastatic pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12431851/
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    Treatment of a severe vascular disease using a bespoke CRISPR-Cas9 base editor in mice
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    pmc.ncbi.nlm.nih.gov/articles/PMC12515372/
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    An injury-associated lobular microniche is associated with the classical tumor cell phenotype in pancreatic cancer
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    pmc.ncbi.nlm.nih.gov/articles/PMC12475445/
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    The DNA replication machinery transmits dual signals to prevent unscheduled licensing and execution of centrosome duplication
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    pmc.ncbi.nlm.nih.gov/articles/PMC12417547/
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    SLC45A4 encodes a peroxisomal putrescine transporter that promotes GABA de novo synthesis
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    pmc.ncbi.nlm.nih.gov/articles/PMC12634670/
  90. pmc.ncbi.nlm.nih.gov pmc.ncbi.nlm.nih.gov
    Coupling Proximity Biotinylation with Genomic Targeting to Characterize Locus-Specific Changes in Chromatin Environments
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