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1,177 Matching Annotations

Oct 2022
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Cytoplasmic SIRT6-mediated ACSL5 deacetylation impedes nonalcoholic fatty liver disease by facilitating hepatic fatty acid oxidation

1
1. scibot 09 Oct 2022
  
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  Cat# CCL-247
  
  DOI: 10.1016/j.molcel.2022.09.018
  
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sciencedirect.com/science/article/pii/S1097276522009078
Sep 2022
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HPV E6 regulates therapy responses in oropharyngeal cancer by repressing the PGC-1<b>α</b>/ERR<b>α</b> axis

1
1. scibot 30 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1172/jci.insight.159600
  
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insight.jci.org/articles/view/159600
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Anti-metastatic effects of 1,2,3,4,6-Penta-O-galloyl-β-D-glucose in colorectal cancer: Regulation of cathepsin B-mediated extracellular matrix dynamics and epithelial-to-mesenchymal transition

1
1. scibot 21 Sep 2022
  
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  DOI: 10.1016/j.phrs.2022.106457
  
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sciencedirect.com/science/article/pii/S1043661822004030
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Special issue “The advance of solid tumor research in China”: Discoidin domain receptor 2 promotes colorectal cancer metastasis by regulating epithelial mesenchymal transition via activating AKT signaling

1
1. scibot 14 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.34227
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34227
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Sensitive and reproducible cell-free methylome quantification with synthetic spike-in controls

1
1. scibot 11 Sep 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.crmeth.2022.100294
  
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sciencedirect.com/science/article/pii/S266723752200176X
Aug 2022
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Substrate spectrum of PPM1D in the cellular response to DNA double-strand breaks

1
1. scibot 27 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2022.104892
  
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sciencedirect.com/science/article/pii/S2589004222011646
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SHMT2-mediated mitochondrial serine metabolism drives 5-FU resistance by fueling nucleotide biosynthesis

1
1. scibot 17 Aug 2022
  
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  ATCCCat# CCL-247
  
  DOI: 10.1016/j.celrep.2022.111233
  
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sciencedirect.com/science/article/pii/S2211124722010506
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Systematic study of tissue factor expression in solid tumors

1
1. scibot 16 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/cnr2.1699
  
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onlinelibrary.wiley.com/doi/10.1002/cnr2.1699
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Enterobacterial LPS-inducible LINC00152 is regulated by histone lactylation and promotes cancer cells invasion and migration

1
1. scibot 13 Aug 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.3389/fcimb.2022.913815
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9359126/
Jul 2022
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Acetylation of p62 regulates base excision repair through interaction with APE1

1
1. scibot 27 Jul 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.celrep.2022.111116
  
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sciencedirect.com/science/article/pii/S2211124722009226
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Lipidomic profiling of exosomes from colorectal cancer cells and patients reveals potential biomarkers

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/1878-0261.13223
  
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ncbi.nlm.nih.gov/pmc/articles/PMC9298677/
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Data Driven and Biophysical Insights into the Regulation of Trafficking Vesicles by Extracellular Matrix Stiffness

1
1. scibot 27 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2022.104721
  
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sciencedirect.com/science/article/pii/S2589004222009932
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Exploring the potential of exosomes in diagnosis and drug delivery for PDAC

1
1. scibot 15 Jul 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1002/ijc.34195
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.34195
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Tumor cell conditioned media drives collagen remodeling via fibroblast and pericyte activation in an in vitro premetastatic niche model

1
1. scibot 08 Jul 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.isci.2022.104645
  
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sciencedirect.com/science/article/pii/S2589004222009178
Jun 2022
academic.oup.com academic.oup.com

MiRNA-Based Therapies for the Treatment of Inflammatory Bowel Disease: What Are We Still Missing?

1
1. scibot 28 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1093/ibd/izac122
  
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academic.oup.com/ibdjournal/advance-article/doi/10.1093/ibd/izac122/6617564
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Identifying enhancers of innate immune signaling as broad-spectrum antivirals active against emerging viruses

1
1. scibot 22 Jun 2022
  
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  ATCCCat# CCL-247
  
  DOI: 10.1016/j.chembiol.2022.05.009
  
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sciencedirect.com/science/article/pii/S245194562200201X
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Structural basis for tunable affinity and specificity of LxCxE-dependent protein interactions with the retinoblastoma protein family

1
1. scibot 18 Jun 2022
  
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  ATCC#: CCL-247
  
  DOI: 10.1016/j.str.2022.05.019
  
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sciencedirect.com/science/article/pii/S0969212622002283
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Time-resolved proximity labeling of protein networks associated with ligand-activated EGFR

1
1. scibot 15 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2022.110950
  
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sciencedirect.com/science/article/pii/S221112472200732X
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RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition

1
1. scibot 11 Jun 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41467-022-30794-7
  
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nature.com/articles/s41467-022-30794-7
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Fatty acid oxidation protects cancer cells from apoptosis by increasing mitochondrial membrane lipids

1
1. scibot 02 Jun 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.celrep.2022.110870
  
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sciencedirect.com/science/article/pii/S2211124722006453
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Intracellular complement C5a/C5aR1 stabilizes β-catenin to promote colorectal tumorigenesis

1
1. scibot 02 Jun 2022
  
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  ATCCCat#CCL-247
  
  DOI: 10.1016/j.celrep.2022.110851
  
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sciencedirect.com/science/article/pii/S2211124722006246
May 2022
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DNA damage promotes HLA class I presentation by stimulating a pioneer round of translation-associated antigen production

1
1. scibot 20 May 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.molcel.2022.04.030
  
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sciencedirect.com/science/article/pii/S1097276522003938
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Whole-genome duplication shapes the aneuploidy landscape of human cancers

1
1. scibot 19 May 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-21-2065
  
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aacrjournals.org/cancerres/article/82/9/1736/694710/Whole-Genome-Duplication-Shapes-the-Aneuploidy
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Posttranslational modification of microtubules by the MATCAP detyrosinase

1
1. scibot 10 May 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1126/science.abn6020
  
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science.org/doi/10.1126/science.abn6020
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Glycine decarboxylase maintains mitochondrial protein lipoylation to support tumor growth

1
1. scibot 05 May 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cmet.2022.04.006
  
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sciencedirect.com/science/article/pii/S1550413122001334
www.cell.com www.cell.com

Systematic discovery of mutation-directed neo-protein-protein interactions in cancer

1
1. scibot 05 May 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.cell.2022.04.014
  
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cell.com/cell/fulltext/S0092-8674(22)00461-5
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FILIP1L loss is a driver of aggressive mucinous colorectal adenocarcinoma and mediates cytokinesis defects through PFDN1

1
1. scibot 04 May 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1158/0008-5472.CAN-21-0897
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8563430/
Apr 2022
www.nature.com www.nature.com

Sister chromatid–sensitive Hi-C to map the conformation of replicated genomes

1
1. scibot 30 Apr 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1038/s41596-022-00687-6
  
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nature.com/articles/s41596-022-00687-6
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Liquid phase separation of NEMO induced by polyubiquitin chains activates NF-κB

1
1. scibot 27 Apr 2022
  
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  CVCL_0291
  
  DOI: 10.1016/j.molcel.2022.03.037
  
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sciencedirect.com/science/article/pii/S1097276522002933
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DNA replication profiling by molecular combing on single DNA fibers

1
1. scibot 15 Apr 2022
  
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  ATCC#CCL-247
  
  DOI: 10.1016/j.xpro.2022.101290
  
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sciencedirect.com/science/article/pii/S2666166722001708
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Interrogation of cancer gene dependencies reveals paralog interactions of autosome and sex chromosome-encoded genes

1
1. scibot 14 Apr 2022
  
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  CVCL_0291
  
  DOI: 10.1016/j.celrep.2022.110636
  
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sciencedirect.com/science/article/pii/S2211124722003886
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Lyso-PAF, a biologically inactive phospholipid, contributes to RAF1 activation

1
1. scibot 13 Apr 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.molcel.2022.03.026
  
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sciencedirect.com/science/article/pii/S1097276522002647
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Novel hybridization- and tag-based error-corrected method for sensitive ctDNA mutation detection using ion semiconductor sequencing

1
1. scibot 12 Apr 2022
  
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  DOI: 10.1038/s41598-022-09698-5
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8986848/
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Linkage of methionine addiction, histone lysine hypermethylation, and malignancy

1
1. scibot 08 Apr 2022
  
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  ATCCCCL-247
  
  DOI: 10.1016/j.isci.2022.104162
  
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sciencedirect.com/science/article/pii/S2589004222004321
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Heat-induced SIRT1-mediated H4K16ac deacetylation impairs resection and SMARCAD1 recruitment to double strand breaks

1
1. scibot 08 Apr 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.1016/j.isci.2022.104142
  
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sciencedirect.com/science/article/pii/S2589004222004126
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Genetic instability from a single S phase after whole-genome duplication

1
1. scibot 08 Apr 2022
  
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MYCMI-7: A Small MYC-Binding Compound that Inhibits MYC: MAX Interaction and Tumor Growth in a MYC-Dependent Manner

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  DOI: 10.1158/2767-9764.CRC-21-0019
  
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aacrjournals.org/cancerrescommun/article/2/3/182/694085/MYCMI-7-A-Small-MYC-Binding-Compound-that-Inhibits
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Suppression of p53 response by targeting p53-Mediator binding with a stapled peptide

1
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  ATCCCCL-247
  
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Tumor targeting with bacterial Shiga toxin B-subunit in genetic porcine models for colorectal cancer and osteosarcoma

1
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  DOI: 10.1158/1535-7163.MCT-21-0445
  
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BPS Publications

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  DOI: 10.1111/bph.15763
  
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bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763
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A clinically relevant heterozygous ATR mutation sensitizes colorectal cancer cells to replication stress

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  DOI: 10.1038/s41598-022-09308-4
  
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Modulation of RNA splicing associated with Wnt signaling pathway using FD-895 and pladienolide B

1
1. scibot 01 Apr 2022
  
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  DOI: 10.18632/aging.203924
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8954975/
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Metabolomics reveals that CAF-derived lipids promote colorectal cancer peritoneal metastasis by enhancing membrane fluidity

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1. scibot 26 Mar 2022
  
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  RRID:CVCL_0291
  
  DOI: 10.7150/ijbs.68484
  
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Neddylation is essential for β-catenin degradation in Wnt signaling pathway

1
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  CVCL_0291
  
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Targeting NKG2A to boost anti-tumor CD8 T-cell responses in human colorectal cancer

1
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Profiling of diverse tumor types establishes the broad utility of VHL-based ProTaCs and triages candidate ubiquitin ligases

1
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translational-medicine.biomedcentral.com translational-medicine.biomedcentral.com

Activation of miR-500a-3p/CDK6 axis suppresses aerobic glycolysis and colorectal cancer progression

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  DOI: 10.1186/s12967-022-03308-8
  
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Cancer-associated fibroblasts at the unfavorable desmoplastic stroma promote colorectal cancer aggressiveness: potential role of ADAM9

1
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PTBP3 modulates P53 expression and promotes colorectal cancer cell proliferation by maintaining UBE4A mRNA stability

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  DOI: 10.1038/s41419-022-04564-8
  
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Protein-lipid interaction at low pH induces oligomerization of the MakA cytotoxin from Vibrio cholerae

1
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.73439
  
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CRAF dimerization with ARAF regulates KRAS-driven tumor growth

2
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  CCL-247
  
  DOI: 10.1016/j.celrep.2022.110351
  
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  DOI: 10.1016/j.celrep.2022.110351
  
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Liquidambaric acid inhibits Wnt/β-catenin signaling and colon cancer via targeting TNF receptor-associated factor 2

1
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  ATCCCat#CCL-247
  
  DOI: 10.1016/j.celrep.2022.110319
  
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Histone chaperone FACT complex coordinates with HIF to mediate an expeditious transcription program to adapt to poorly oxygenated cancers

1
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  ATCCCat#CCL-247
  
  DOI: 10.1016/j.celrep.2022.110304
  
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SPARCLE, a p53-induced lncRNA, controls apoptosis after genotoxic stress by promoting PARP-1 cleavage

1
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  DOI: 10.1016/j.molcel.2022.01.001
  
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Allele-specific endogenous tagging and quantitative analysis of β-catenin in colorectal cancer cells

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8752093/
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Feedback-regulated transcriptional repression of FBXO31 by c-Myc triggers ovarian cancer tumorigenesis

1
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  RRID: CVCL_0291
  
  DOI: 10.1002/ijc.33854
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33854
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NEBL and AKT1 maybe new targets to eliminate the colorectal cancer cells resistance to oncolytic effect of vesicular stomatitis virus M-protein

1
1. scibot 05 Jan 2022
  
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  DOI: 10.1016/j.omto.2021.11.013
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8666707/
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AP-2α Regulates S-phase and is a Marker for Sensitivity to PI3K-inhibitor Buparlisib in Colon Cancer

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8254761/
Dec 2021
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Association of RanGAP to nuclear pore complex component, RanBP2/Nup358, is required for pupal development in Drosophila

1
1. scibot 29 Dec 2021
  
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  CCL-247
  
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USP19 exacerbates lipogenesis and colorectal carcinogenesis by stabilizing ME1

1
1. scibot 29 Dec 2021
  
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  CCL-247
  
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MLH1 mediates cytoprotective nucleophagy to resist 5-Fluorouracil-induced cell death in colorectal carcinoma

1
1. scibot 22 Dec 2021
  
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  DOI: 10.1016/j.neo.2021.12.003
  
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Integrative analysis from multi-center studies identities a consensus machine learning-derived lncRNA signature for stage II/III colorectal cancer

1
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MED12 and BRD4 cooperate to sustain cancer growth upon loss of mediator kinase

1
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  DOI: 10.1016/j.molcel.2021.11.015
  
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Glutamine deprivation triggers NAGK-dependent hexosamine salvage

1
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  RRID:CVCL_0291
  
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Combined Inhibition of p38MAPK and PIKfyve Synergistically Disrupts Autophagy to Selectively Target Cancer Cells

1
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  DOI: 10.1158/0008-5472.CAN-20-3371
  
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Redox-sensitive cyclophilin A elicits chemoresistance through realigning cellular oxidative status in colorectal cancer

1
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  DOI: 10.1016/j.celrep.2021.110069
  
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Metabolic targeting of cancer by a ubiquinone uncompetitive inhibitor of mitochondrial complex I

1
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sciencedirect.com/science/article/pii/S2451945621004797
Nov 2021
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Temporal proteomics reveal specific cell cycle oncoprotein downregulation by p97/VCP inhibition

1
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Statins affect cancer cell plasticity with distinct consequences for tumor progression and metastasis

2
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  CCL-247
  
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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer

1
1. scibot 23 Nov 2021
  
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  DOI: 10.1016/j.bioorg.2021.105505
  
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sciencedirect.com/science/article/pii/S004520682100883X
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FEBS Press

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1. scibot 19 Nov 2021
  
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  CCL-247
  
  DOI: 10.1111/febs.16261
  
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febs.onlinelibrary.wiley.com/doi/10.1111/febs.16261
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Transcription-wide mapping of dihydrouridine reveals that mRNA dihydrouridylation is required for meiotic chromosome segregation

1
1. scibot 19 Nov 2021
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2021.11.003
  
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Short-chain fatty acids activate acetyltransferase p300

1
1. scibot 19 Nov 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.7554/eLife.72171
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8585482/
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Toward comprehensive imaging of oncolytic viroimmunotherapy

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1. scibot 18 Nov 2021
  
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  DOI: 10.1016/j.omto.2021.06.010
  
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Genome-wide CRISPR-Cas9 screens identify mechanisms of BET bromodomain inhibitor sensitivity

1
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  DOI: 10.1016/j.isci.2021.103323
  
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Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1

1
1. scibot 12 Nov 2021
  
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  CCL-247
  
  DOI: 10.1016/j.molcel.2021.10.015
  
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Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling

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  CCL-247
  
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Molecular modelling of the FOXO4-TP53 interaction to design senolytic peptides for the elimination of senescent cancer cells

1
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  DOI: 10.1016/j.ebiom.2021.103646
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8546421/
Oct 2021
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Inhibition of glucose transport synergizes with chemical or genetic disruption of mitochondrial metabolism and suppresses TCA cycle-deficient tumors

1
1. scibot 29 Oct 2021
  
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  DOI: 10.1016/j.chembiol.2021.10.007
  
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Reprogramming CBX8-PRC1 function with a positive allosteric modulator

1
1. scibot 29 Oct 2021
  
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  CCL-247
  
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Subtractive CRISPR screen identifies the ATG16L1/vacuolar ATPase axis as required for non-canonical LC3 lipidation

1
1. scibot 27 Oct 2021
  
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XBP1 regulates the protumoral function of tumor-associated macrophages in human colorectal cancer

1
1. scibot 23 Oct 2021
  
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  DOI: 10.1038/s41392-021-00761-7
  
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nature.com/articles/s41392-021-00761-7
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USP7 and VCPFAF1 define the SUMO/Ubiquitin landscape at the DNA replication fork

1
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  CCL-247
  
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Shift in MSL1 alternative polyadenylation in response to DNA damage protects cancer cells from chemotherapeutic agent-induced apoptosis

1
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  DOI: 10.1016/j.celrep.2021.109815
  
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Tiered testing of micro- and nanoplastics using intestinal in vitro models to support hazard assessments

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  DOI: 10.1016/j.envint.2021.106921
  
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Proteome-wide mapping of short-lived proteins in human cells

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  DOI: 10.1016/j.molcel.2021.09.015
  
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Identification of new reference genes with stable expression patterns for gene expression studies using human cancer and normal cell lines

1
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ncbi.nlm.nih.gov/pmc/articles/PMC8484624/
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Pituitary somatotroph adenoma-derived exosomes: characterization of nonhormonal actions

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1. scibot 01 Oct 2021
  
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  DOI: 10.1210/clinem/dgab651
  
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academic.oup.com/jcem/advance-article/doi/10.1210/clinem/dgab651/6360746
Sep 2021
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Evaluation of 64Cu-Labeled New Anti-EGFR Antibody NCAB001 with Intraperitoneal Injection for Early PET Diagnosis of Pancreatic Cancer in Orthotopic Tumor-Xenografted Mice and Nonhuman Primates

1
1. scibot 29 Sep 2021
  
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  DOI: 10.3390/ph14100950
  
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mdpi.com/1424-8247/14/10/950
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Oncogene-dependent sloppiness in mRNA translation

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1. scibot 25 Sep 2021
  
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  DOI: 10.1016/j.molcel.2021.09.002
  
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CRL4DTL E3 ligase induces degradation of the DNA replication initiation factor TICRR/TRESLIN specifically during S phase

1
1. scibot 24 Sep 2021
  
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  CCL-247
  
  DOI: 10.1093/nar/gkab805
  
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academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab805/6371977
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Alternative microexon splicing by RBFOX2 and PTBP1 is associated with metastasis in colorectal cancer

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1. scibot 23 Sep 2021
  
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  DOI: 10.1002/ijc.33758
  
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onlinelibrary.wiley.com/doi/10.1002/ijc.33758
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ATF3 promotes the serine synthesis pathway and tumor growth under dietary serine restriction

1
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  CCL-247
  
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Treatment resistance analysis reveals GLUT-1-mediated glucose uptake as a major target of synthetic rocaglates in cancer cells

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1. scibot 22 Sep 2021
  
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  DOI: 10.1002/cam4.4212
  
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onlinelibrary.wiley.com/doi/10.1002/cam4.4212
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Anticancer potential of limonoids from Swietenia macrophylla: Genotoxic, antiproliferative and proapoptotic effects towards human colorectal cancer

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Expanding control of the tumor cell cycle with a CDK2/4/6 inhibitor

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  CCL-247
  
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REV1-Polζ maintains the viability of homologous recombination-deficient cancer cells through mutagenic repair of PRIMPOL-dependent ssDNA gaps

1
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SPT5 stabilization of promoter-proximal RNA polymerase II

1
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  CCL-247
  
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High-grade serous ovarian tumor cells modulate NK cell function to create an immune-tolerant microenvironment

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  CCL-247
  
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iRQC, a surveillance pathway for 40S ribosomal quality control during mRNA translation initiation

1
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  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109642
  
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sciencedirect.com/science/article/pii/S2211124721010858
Aug 2021
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YKL-40 protein expression in human tumor samples and human tumor cell line xenografts: implications for its use in tumor models

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  DOI: 10.1007/s13402-021-00630-z
  
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link.springer.com/article/10.1007/s13402-021-00630-z
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Entosis is induced by UV radiation.

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Follistatin-Like 3 Enhances Invasion and Metastasis via β-Catenin-Mediated EMT and Aerobic Glycolysis in Colorectal Cancer

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  DOI: 10.3389/fcell.2021.660159
  
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ncbi.nlm.nih.gov/pmc/articles/PMC8355564/
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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism

1
1. scibot 14 Aug 2021
  
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  RRID:CVCL_0291
  
  DOI: 10.1101/141952
  
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biorxiv.org/content/10.1101/141952v4
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Untitled document

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KREMEN1 Is a Host Entry Receptor for a Major Group of Enteroviruses

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BARD1 reads H2A lysine 15 ubiquitination to direct homologous recombination

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Oxaliplatin resistance in colorectal cancer enhances TRAIL sensitivity via death receptor 4 upregulation and lipid raft localization

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Gene copy-number changes and chromosomal instability induced by aneuploidy confer resistance to chemotherapy

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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.

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A subset of CB002 xanthine analogs bypass p53-signaling to restore a p53 transcriptome and target an S-phase cell cycle checkpoint in tumors with mutated-p53

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Tissue of origin dictates GOT1 dependence and confers synthetic lethality to radiotherapy

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FEBS Press

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An mTORC1-to-CDK1 Switch Maintains Autophagy Suppression during Mitosis

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Antisense-Mediated Transcript Knockdown Triggers Premature Transcription Termination

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  HCT116
  
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Targeting Excessive EZH1 and EZH2 Activities for Abnormal Histone Methylation and Transcription Network in Malignant Lymphomas

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  HCT116
  
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Dynamic Regulation of ME1 Phosphorylation and Acetylation Affects Lipid Metabolism and Colorectal Tumorigenesis

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NFE2L3 Controls Colon Cancer Cell Growth through Regulation of DUX4, a CDK1 Inhibitor

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TEX264 Is an Endoplasmic Reticulum-Resident ATG8-Interacting Protein Critical for ER Remodeling during Nutrient Stress

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Widespread and Functional RNA Circularization in Localized Prostate Cancer

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Oncotarget | Targeting transcription factor TCF4 by γ-Mangostin, a natural xanthone

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Synthetic Lethal Interaction of SHOC2 Depletion with MEK Inhibition in RAS-Driven Cancers

1
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  HCT116
  
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Dynamic Incorporation of Histone H3 Variants into Chromatin Is Essential for Acquisition of Aggressive Traits and Metastatic Colonization

1
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  HCC116
  
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The Cancer SENESCopedia: A delineation of cancer cell senescence

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Ethanol promotes alcohol-related colorectal cancer metastasis via the TGF-β/RUNX3/Snail axis by inducing TGF-β1 upregulation and RUNX3 cytoplasmic mislocalization

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Oncogenic MYC amplifies mitotic perturbations

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  DOI: 10.1098/rsob.190136
  
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Long non‐coding RNA CCAL transferred from fibroblasts by exosomes promotes chemoresistance of colorectal cancer cells

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Impaired Mitochondrial ATP Production Downregulates Wnt Signaling via ER Stress Induction

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  Human: HCT116
  
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Blockade of the LRP16-PKR-NF-κB signaling axis sensitizes colorectal carcinoma cells to DNA-damaging cytotoxic therapy

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  DOI: 10.7554/eLife.27301
  
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Untitled document

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Explosive mutation accumulation triggered by heterozygous human Pol ε proofreading-deficiency is driven by suppression of mismatch repair

2
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The Natural Product Butylcycloheptyl Prodiginine Binds Pre-miR-21, Inhibits Dicer-Mediated Processing of Pre-miR-21, and Blocks Cellular Proliferation

1
1. scibot 28 Jul 2021
  
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Distinct Roles of RZZ and Bub1-KNL1 in Mitotic Checkpoint Signaling and Kinetochore Expansion

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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer

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Tumour-derived PGD2 and NKp30-B7H6 engagement drives an immunosuppressive ILC2-MDSC axis

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ASN007 is a selective ERK1/2 inhibitor with preferential activity against RAS-and RAF-mutant tumors

1
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CETSA interaction proteomics define specific RNA-modification pathways as key components of fluorouracil-based cancer drug cytotoxicity

1
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Glycerol-3-phosphate biosynthesis regenerates cytosolic NAD+ to alleviate mitochondrial disease

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BTN2A1, an immune checkpoint targeting Vγ9Vδ2 T cell cytotoxicity against malignant cells

1
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Protein disulfide isomerase inhibits endoplasmic reticulum stress response and apoptosis via its oxidoreductase activity in colorectal cancer

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The RAS GTPase RIT1 compromises mitotic fidelity through spindle assembly checkpoint suppression

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Establishment of live-cell-based coupled assay system for identification of compounds to modulate metabolic activities of cells

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Jun 2021
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STIM1 Mediates Calcium-dependent Epigenetic Reprogramming in Pancreatic Cancer

1
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  DOI: 10.1158/0008-5472.CAN-20-2874
  
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Cytoplasmic mRNA decay represses RNA polymerase II transcription during early apoptosis

1
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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer

1
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KSR1- and ERK-dependent translational regulation of the epithelial-to-mesenchymal transition

1
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Targeted mass-spectrometry-based assays enable multiplex quantification of receptor tyrosine kinase, MAP kinase, and AKT signaling

1
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A Novel Benzopyrane Derivative Targeting Cancer Cell Metabolic and Survival Pathways

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Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects

1
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TRIM7 inhibits enterovirus replication and promotes emergence of a viral variant with increased pathogenicity

1
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Cytoplasmic RAD23B interacts with CORO1C to synergistically promote colorectal cancer progression and metastasis

1
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Endogenous p53 expression in human and mouse is not regulated by its 3′UTR

1
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Suppression of β-catenin signaling in colon carcinoma cells by a bacterial protein

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Novel functional variants in the Notch pathway and survival of Chinese colorectal cancer

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Immuno-PET Molecular Imaging of RANKL in Cancer

1
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Grade-targeted nanoparticles for improved hypoxic tumor microenvironment and enhanced photodynamic cancer therapy

1
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Survivin Expression is Differentially Regulated by a Selective Crosstalk between Rbm38 and miRNAs let-7b or miR-203a

1
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BPS Publications

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Tandem Deubiquitination and Acetylation of SPRTN Promotes DNA-Protein Crosslink Repair and Protects against Aging

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POLE Mutation Spectra Are Shaped by the Mutant Allele Identity, Its Abundance, and Mismatch Repair Status

1
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Synergistic antitumor activity of DHA and JQ1 in colorectal carcinoma

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FEBS Press

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Malic enzyme 2 connects the Krebs cycle intermediate fumarate to mitochondrial biogenesis

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sciencedirect.com/science/article/pii/S1550413121001108
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The ZMYND8-regulated mevalonate pathway endows YAP-high intestinal cancer with metabolic vulnerability

1
1. scibot 01 May 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.molcel.2021.04.009
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S1097276521003142
www.sciencedirect.com www.sciencedirect.com

The Source of Glycolytic Intermediates in Mammalian Tissues

1
1. scibot 01 May 2021
  
  in Public
  
  CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.020
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S1550413120307282
Apr 2021
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Tumor Reliance on Cytosolic versus Mitochondrial One-Carbon Flux Depends on Folate Availability

1
1. scibot 30 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.cmet.2020.12.002
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S1550413120306574
link.springer.com link.springer.com

Glutamine deficiency promotes stemness and chemoresistance in tumor cells through DRP1-induced mitochondrial fragmentation

1
1. scibot 29 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1007/s00018-021-03818-6
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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link.springer.com/article/10.1007/s00018-021-03818-6
www.sciencedirect.com www.sciencedirect.com

Opening of cohesin’s SMC ring is essential for timely DNA replication and DNA loop formation

1
1. scibot 28 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108999
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721003132
www.sciencedirect.com www.sciencedirect.com

Development and pre-clinical testing of a novel hypoxia-activated KDAC inhibitor

1
1. scibot 28 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.chembiol.2021.04.004
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2451945621001598
www.sciencedirect.com www.sciencedirect.com

Hypomorph Mutation-Directed Small-Molecule Protein-Protein Interaction Inducers to Restore Mutant SMAD4-Suppressed TGF-β Signaling

2
1. scibot 28 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
  What is this?
  
  RRID:CVCL_0291
2. scibot 08 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.chembiol.2020.11.010
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S2451945620304736
www.sciencedirect.com www.sciencedirect.com

Triplexed Affinity Reagents to Sample the Mammalian Inositol Pyrophosphate Interactome

1
1. scibot 27 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.chembiol.2020.07.017
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291 RRIDCUR:Missing
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RRIDCUR:Missing

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sciencedirect.com/science/article/pii/S2451945620302907
www.sciencedirect.com www.sciencedirect.com

Large-Scale Topological Changes Restrain Malignant Progression in Colorectal Cancer

1
1. scibot 24 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.cell.2020.07.030
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S0092867420309387
www.sciencedirect.com www.sciencedirect.com

Extracellular Vesicle and Particle Biomarkers Define Multiple Human Cancers

1
1. scibot 24 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.cell.2020.07.009
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S0092867420308746
www.sciencedirect.com www.sciencedirect.com

Self-Reporting Transposons Enable Simultaneous Readout of Gene Expression and Transcription Factor Binding in Single Cells

1
1. scibot 24 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.cell.2020.06.037
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S009286742030814X
www.sciencedirect.com www.sciencedirect.com

MLH1 Deficiency-Triggered DNA Hyperexcision by Exonuclease 1 Activates the cGAS-STING Pathway

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2020.11.004
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Validated RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S1535610820305961
www.sciencedirect.com www.sciencedirect.com

Integrated Omics of Metastatic Colorectal Cancer

1
1. scibot 22 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.ccell.2020.08.002
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Validated RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S153561082030413X
www.sciencedirect.com www.sciencedirect.com

High-content, targeted RNA-seq screening in organoids for drug discovery in colorectal cancer

1
1. scibot 21 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.celrep.2021.109026
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291 RRIDCUR:Missing
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sciencedirect.com/science/article/pii/S2211124721003405
www.tandfonline.com www.tandfonline.com

The Targeting Effect of Cetuximab Combined with PD-L1 Blockade against EGFR-Expressing Tumors in a Tailored CD16-CAR T-Cell Reporter System

1
1. scibot 19 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1080/07357907.2021.1894570
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @scibot
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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tandfonline.com/doi/full/10.1080/07357907.2021.1894570
www.sciencedirect.com www.sciencedirect.com

Efferocytosis by Paneth cells within the intestine

1
1. scibot 14 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.cub.2021.03.055
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Validated RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S0960982221004280
www.sciencedirect.com www.sciencedirect.com

SK4 oncochannels regulate calcium entry and promote cell migration in KRAS-mutated colorectal cancer

1
1. scibot 12 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.ceca.2021.102384
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @bandrow
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S0143416021000385
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Creatine promotes cancer metastasis through activation of Smad2/3

1
1. scibot 06 Apr 2021
  
  in Public
  
  Cat#CCL-247
  
  DOI: 10.1016/j.cmet.2021.03.009
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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RRIDCUR:Missing

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sciencedirect.com/science/article/pii/S1550413121001169
www.sciencedirect.com www.sciencedirect.com

SIRT2 promotes BRCA1-BARD1 heterodimerization through deacetylation

1
1. scibot 01 Apr 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108921
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S2211124721002357
www.sciencedirect.com www.sciencedirect.com

PPP6C negatively regulates oncogenic ERK signaling through dephosphorylation of MEK

1
1. scibot 01 Apr 2021
  
  in Public
  
  RRID:CVCL_0291
  
  DOI: 10.1016/j.celrep.2021.108928
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Validated RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S2211124721002424
Mar 2021
www.sciencedirect.com www.sciencedirect.com

SGK1 signaling promotes glucose metabolism and survival in extracellular matrix detached cells

1
1. scibot 18 Mar 2021
  
  in Public
  
  CCL-247
  
  DOI: 10.1016/j.celrep.2021.108821
  
  Resource: (KCB Cat# KCB 200706YJ, RRID:CVCL_0291)
  
  Curator: @Naa003
  
  SciCrunch record: RRID:CVCL_0291
  
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  RRIDCUR:Missing RRID:CVCL_0291
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sciencedirect.com/science/article/pii/S2211124721001352

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