2,326 Matching Annotations
  1. Jun 2022
  2. aacrjournals.org aacrjournals.org
    Porcupine inhibition disrupts mitochondrial function and homeostasis in WNT ligand-addicted pancreatic cancer
    1
    1. scibot 14 Jun 2022
      RRID:SCR_008520

      DOI: 10.1158/1535-7163.MCT-21-0623

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    aacrjournals.org/mct/article/21/6/936/699192/Porcupine-Inhibition-Disrupts-Mitochondrial
  3. www.sciencedirect.com www.sciencedirect.com
    Evaluating the glycolytic potential of mouse costimulated effector CD8+ T cells ex vivo
    1
    1. scibot 08 Jun 2022
      RRID:SCR_008520

      DOI: 10.1016/j.xpro.2022.101441

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    sciencedirect.com/science/article/pii/S2666166722003215
  4. www.sciencedirect.com www.sciencedirect.com
    BCL6-dependent TCF-1+ progenitor cells maintain effector and helper CD4+ T cell responses to persistent antigen
    1
    1. scibot 03 Jun 2022
      SCR_008520

      DOI: 10.1016/j.immuni.2022.05.003

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    sciencedirect.com/science/article/pii/S1074761322002230
  5. www.sciencedirect.com www.sciencedirect.com
    Intrinsic antiviral immunity of barrier cells revealed by an iPSC-derived blood-brain barrier cellular model
    1
    1. scibot 03 Jun 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110885

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    sciencedirect.com/science/article/pii/S221112472200660X
  6. www.sciencedirect.com www.sciencedirect.com
    Proprotein convertase PCSK9 affects expression of key surface proteins in human pancreatic beta cells via intra- and extracellular regulatory circuits.
    1
    1. scibot 03 Jun 2022
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      DOI: 10.1016/j.jbc.2022.102096

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    sciencedirect.com/science/article/pii/S0021925822005373
  7. www.sciencedirect.com www.sciencedirect.com
    Mediator recruits the cohesin loader Scc2 to RNA Pol II-transcribed genes and promotes sister chromatid cohesion
    1
    1. scibot 02 Jun 2022
      RRID# SCR_008520

      DOI: 10.1016/j.cub.2022.05.019

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    sciencedirect.com/science/article/pii/S0960982222007783
  8. link.springer.com link.springer.com
    Platinum-induced mitochondrial OXPHOS contributes to cancer stem cell enrichment in ovarian cancer
    1
    1. scibot 01 Jun 2022
      RRID:SCR_008520

      DOI: 10.1186/s12967-022-03447-y

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    link.springer.com/article/10.1186/s12967-022-03447-y
  9. May 2022
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Binary outcomes of enhancer activity underlie stable random monoallelic expression
    1
    1. scibot 28 May 2022
      RRID:SCR_008520

      DOI: 10.7554/eLife.74204

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    ncbi.nlm.nih.gov/pmc/articles/PMC9135403/
  11. www.sciencedirect.com www.sciencedirect.com
    Tumor-associated macrophage heterogeneity is driven by tissue territories in breast cancer
    1
    1. scibot 26 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110865

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    sciencedirect.com/science/article/pii/S2211124722006386
  12. www.sciencedirect.com www.sciencedirect.com
    Corneal tissue-resident memory T cells form a unique immune compartment at the ocular surface
    1
    1. scibot 26 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110852

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    sciencedirect.com/science/article/pii/S2211124722006258
  13. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    A human breast atlas integrating single-cell proteomics and transcriptomics
    1
    1. scibot 26 May 2022
      SCR_008520

      DOI: 10.1016/j.devcel.2022.05.003

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    pubmed.ncbi.nlm.nih.gov/35617956/
  14. www.sciencedirect.com www.sciencedirect.com
    DRP1 levels determine the apoptotic threshold during embryonic differentiation through a mitophagy-dependent mechanism
    1
    1. scibot 25 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.devcel.2022.04.020

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    sciencedirect.com/science/article/pii/S1534580722003069
  15. pubs.acs.org pubs.acs.org
    Simultaneous Delivery of Doxorubicin and Protease Inhibitor Derivative to Solid Tumors via Star-Shaped Polymer Nanomedicines Overcomes P-gp- and STAT3-Mediated Chemoresistance
    1
    1. scibot 24 May 2022
      RRID:SCR_008520

      DOI: 10.1021/acs.biomac.2c00256

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    pubs.acs.org/doi/full/10.1021/acs.biomac.2c00256
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    DNA-PK promotes DNA end resection at DNA double strand breaks in G0 cells
    1
    1. scibot 24 May 2022
      RRID:SCR_008520

      DOI: 10.7554/eLife.74700

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    ncbi.nlm.nih.gov/pmc/articles/PMC9122494/
  17. www.sciencedirect.com www.sciencedirect.com
    The C5a-C5aR1 complement axis is essential for neutrophil recruitment to draining lymph nodes via high endothelial venules in cutaneous leishmaniasis
    1
    1. scibot 21 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110777

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    sciencedirect.com/science/article/pii/S2211124722005411
  18. elifesciences.org elifesciences.org
    Integrative analysis of scRNA-seq and scATAC-seq revealed transit-amplifying thymic epithelial cells expressing autoimmune regulator
    1
    1. scibot 21 May 2022
      RRID:SCR_008520

      DOI: 10.7554/eLife.73998

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    elifesciences.org/articles/73998
  19. www.sciencedirect.com www.sciencedirect.com
    Broad and ultra-potent cross-clade neutralization of HIV-1 by a vaccine-induced CD4 binding site bovine antibody
    1
    1. scibot 19 May 2022
      SCR_008520

      DOI: 10.1016/j.xcrm.2022.100635

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    sciencedirect.com/science/article/pii/S2666379122001604
  20. aacrjournals.org aacrjournals.org
    Secretion of interleukin-1 by dedifferentiated melanoma cells inhibits JAK1-STAT3-driven actomyosin contractility of lymph node fibroblastic reticular cells
    1
    1. scibot 19 May 2022
      RRID:SCR_008520

      DOI: 10.1158/0008-5472.CAN-21-0501

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    aacrjournals.org/cancerres/article/82/9/1774/694699/Secretion-of-IL1-by-Dedifferentiated-Melanoma
  21. www.sciencedirect.com www.sciencedirect.com
    T cell transcription factor expression evolves over time in granulomas from Mycobacterium tuberculosis-infected cynomolgus macaques
    1
    1. scibot 19 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110826

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    sciencedirect.com/science/article/pii/S2211124722005976
  22. www.sciencedirect.com www.sciencedirect.com
    A family of conserved bacterial virulence factors dampens interferon responses by blocking calcium signaling
    1
    1. scibot 18 May 2022
      RRID: SCR_008520

      DOI: 10.1016/j.cell.2022.04.028

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    sciencedirect.com/science/article/pii/S0092867422005268
  23. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Integrated Human and Murine Clinical Study Establishes Clinical Efficacy of Ruxolitinib in Chronic Myelomonocytic Leukemia
    1
    1. scibot 18 May 2022
      RRID:SCR_008520

      DOI: 10.1158/1078-0432.CCR-21-0935

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    ncbi.nlm.nih.gov/pmc/articles/PMC8595542/
  24. aacrjournals.org aacrjournals.org
    Genomic and single-cell landscape reveals novel drivers and therapeutic vulnerabilities of transformed cutaneous T-cell lymphomaGenomic and single-cell landscape of transformed CTCL
    1
    1. scibot 13 May 2022
      RRID:SCR_008520

      DOI: 10.1158/2159-8290.CD-21-1207

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    aacrjournals.org/cancerdiscovery/article/12/5/1294/694564/Genomic-and-Single-Cell-Landscape-Reveals-Novel
  25. aacrjournals.org aacrjournals.org
    EGFR inhibition potentiates FGFR inhibitor therapy and overcomes resistance in FGFR2 fusion-positive cholangiocarcinoma
    1
    1. scibot 13 May 2022
      RRID:SCR_008520

      DOI: 10.1158/2159-8290.CD-21-1168

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    aacrjournals.org/cancerdiscovery/article/12/5/1378/694560/EGFR-Inhibition-Potentiates-FGFR-Inhibitor-Therapy
  26. www.sciencedirect.com www.sciencedirect.com
    Germinal center expansion but not plasmablast differentiation is proportional to peptide-MHCII density via CD40-CD40L signaling strength
    1
    1. scibot 12 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110763

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    sciencedirect.com/science/article/pii/S2211124722005277
  27. www.sciencedirect.com www.sciencedirect.com
    Analysis of the interplay between hepatitis B virus-positive hepatocytes and Kupffer cells ex vivo using mice as a model
    1
    1. scibot 12 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.xpro.2022.101364

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    sciencedirect.com/science/article/pii/S2666166722002441
  28. link.springer.com link.springer.com
    Aquaporin-4 prevents exaggerated astrocytosis and structural damage in retinal inflammation
    1
    1. scibot 12 May 2022
      RRID:SCR_008520

      DOI: 10.1007/s00109-022-02202-6

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    link.springer.com/article/10.1007/s00109-022-02202-6
  29. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bone Marrow-Derived Stem Cell Factor Regulates Prostate Cancer-Induced Shifts in Pre-Metastatic Niche Composition
    1
    1. scibot 11 May 2022
      RRID:SCR_008520

      DOI: 10.3389/fonc.2022.855188

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    ncbi.nlm.nih.gov/pmc/articles/PMC9063312/
  30. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Augmentation of Extracellular ATP Synergizes With Chemotherapy in Triple Negative Breast Cancer
    1
    1. scibot 11 May 2022
      RRID:SCR_008520

      DOI: 10.3389/fonc.2022.855032

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    ncbi.nlm.nih.gov/pmc/articles/PMC9065442/
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The oncoprotein BCL6 enables solid tumor cells to evade genotoxic stress
    1
    1. scibot 11 May 2022
      RRID:SCR_008520

      DOI: 10.7554/eLife.69255

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    ncbi.nlm.nih.gov/pmc/articles/PMC9064299/
  32. www.sciencedirect.com www.sciencedirect.com
    PTBP1 promotes hematopoietic stem cell maintenance and red blood cell development by ensuring sufficient availability of ribosomal constituents
    1
    1. scibot 11 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110793

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    sciencedirect.com/science/article/pii/S2211124722005605
  33. www.sciencedirect.com www.sciencedirect.com
    KSHV episome tethering sites on host chromosomes and regulation of latency-lytic switch by CHD4
    1
    1. scibot 11 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.celrep.2022.110788

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    sciencedirect.com/science/article/pii/S2211124722005551
  34. www.sciencedirect.com www.sciencedirect.com
    PDGFRα-induced stromal maturation is required to restrain postnatal intestinal epithelial stemness and promote defense mechanisms
    1
    1. scibot 06 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.stem.2022.04.005

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    sciencedirect.com/science/article/pii/S1934590922001588
  35. www.sciencedirect.com www.sciencedirect.com
    Stem-cell-derived trophoblast organoids model human placental development and susceptibility to emerging pathogens
    1
    1. scibot 06 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.stem.2022.04.004

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    sciencedirect.com/science/article/pii/S1934590922001576
  36. www.sciencedirect.com www.sciencedirect.com
    Intracellular infection and immune system cues rewire adipocytes to acquire immune function
    1
    1. scibot 05 May 2022
      RRID:SCR_008520

      DOI: 10.1016/j.cmet.2022.04.008

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    sciencedirect.com/science/article/pii/S1550413122001358
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Characteristics of immune memory and effector activity to cancer-expressed MHC class I phosphopeptides differ in healthy donors and ovarian cancer patients
    1
    1. scibot 04 May 2022
      RRID:SCR_008520

      DOI: 10.1158/2326-6066.CIR-21-0111

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    ncbi.nlm.nih.gov/pmc/articles/PMC8568670/
  38. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Selective requirement of MYB for oncogenic hyperactivation of a translocated enhancer in leukemia
    1
    1. scibot 03 May 2022
      RRID:SCR_008520

      DOI: 10.1158/2159-8290.CD-20-1793

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    ncbi.nlm.nih.gov/pmc/articles/PMC8563373/
  39. Apr 2022
  40. academic.oup.com academic.oup.com
    Immunosuppressive tumor microenvironment in Uterine Serous Carcinoma via CCL7 signal with myeloid-derived suppressor cells
    1
    1. scibot 29 Apr 2022
      RRID:SCR_008520

      DOI: 10.1093/carcin/bgac032

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac032/6556146
  41. academic.oup.com academic.oup.com
    TNFɑ Antagonist in Combination with PD-1 Blocker to Prevent or Retard Malignant Transformation of B[a]P-induced Chronic Lung Inflammation
    1
    1. scibot 29 Apr 2022
      RRID:SCR_008520

      DOI: 10.1093/carcin/bgac024

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    academic.oup.com/carcin/advance-article/doi/10.1093/carcin/bgac024/6540320
  42. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 28 Apr 2022
      RRID:SCR_008520

      DOI: 10.1111/bph.15838

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15838
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo
    1
    1. scibot 27 Apr 2022
      SCR_008520

      DOI: 10.3389/fimmu.2022.861681

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    Contact-Dependent Granzyme B-Mediated Cytotoxicity of Th17-Polarized Cells Toward Human Oligodendrocytes
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    Inflammation induces pro-NETotic neutrophils via TNFR2 signaling
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    Thymidine starvation promotes c-di-AMP-dependent inflammation during pathogenic bacterial infection
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    H3K4 methylation by SETD1A/BOD1L facilitates RIF1-dependent NHEJ
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    ILC precursors differentiate into metabolically distinct ILC1-like cells during Mycobacterium tuberculosis infection
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    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
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    A Foxo1-Klf2-S1pr1-Gnai1-Rac1 signaling axis is a critical mediator of Ostm1 regulatory network in T-lymphopoiesis
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    Protection of nascent DNA at stalled replication forks is mediated by phosphorylation of RIF1 intrinsically disordered region
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    TNF-α sculpts a maturation process in vivo by pruning tolerogenic dendritic cells
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    Extracellular Nicotinamide Phosphoribosyltransferase boosts IFNγ-induced macrophage polarization independently of TLR4
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    TMPRSS2-ERG promotes the initiation of prostate cancer by suppressing oncogene-induced senescence
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    Human pluripotent stem cell-derived myogenic progenitors undergo maturation to quiescent satellite cells upon engraftment
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    Type 1 conventional dendritic cells maintain and guide the differentiation of precursors of exhausted T cells in distinct cellular niches
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    Characterization of the secretome, transcriptome and proteome of human β cell line EndoC-βH1
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    Astrocytes and oligodendrocytes undergo subtype-specific transcriptional changes in Alzheimer’s disease
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    mDKN-01, a Novel Anti-DKK1 mAb, Enhances Innate Immune Responses in the Tumor Microenvironment
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    Combinatorial analysis reveals highly coordinated early-stage immune reactions that predict later antiviral immunity in mild COVID-19 patients
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    Reprogramming and redifferentiation of mucosal-associated invariant T cells reveal tumor inhibitory activity
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    Cell-surface tethered promiscuous biotinylators enable comparative small-scale surface proteomic analysis of human extracellular vesicles and cells
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    NADPH metabolism determines the leukemogenic capacity and drug resistance of AML cells
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    Subversion of serotonin-receptor signaling in osteoblasts by kynurenine drives Acute Myeloid Leukemia
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    Acquired resistance to EZH2 inhibitor GSK343 promotes the differentiation of human DLBCL cell lines towards an ABC-like phenotype
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    Development of novel aptamer-based targeted chemotherapy for bladder cancer
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    Exploiting flow cytometry for the unbiased quantification of protein inclusions in Caenorhabditis elegans
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    Inhibition of CDK4/6 promotes CD8 T cell memory formation
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    Maintenance of glutamine synthetase expression alleviates endotoxin-induced sepsis via alpha-ketoglutarate-mediated demethylation
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    Allogeneic Anti-BCMA CAR T Cells Are Superior to Multiple Myeloma-derived CAR T Cells in Preclinical Studies and May Be Combined with Gamma Secretase Inhibitors
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    Secondary influenza challenge triggers resident memory B cell migration and rapid relocation to boost antibody secretion at infected sites
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    Ligand-independent oligomerization of TACI is controlled by the transmembrane domain and regulates proliferation of activated B cells
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    PRMT7 ablation stimulates anti-tumor immunity and sensitizes melanoma to immune checkpoint blockade
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    Type 1 innate lymphoid cells regulate the onset of Toxoplasma gondii-induced neuroinflammation
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    Viperin triggers ribosome collision-dependent translation inhibition to restrict viral replication
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    Reprogramming bone progenitor identity and potency through control of collagen density and oxygen tension
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    Conduit CAR: Redirecting CAR T-Cell Specificity with A Universal and Adaptable Bispecific Antibody Platform
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    Interferon-gamma inhibits influenza A virus cellular attachment by reducing sialic acid cluster size
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  83. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Rationally designed immunogens enable immune focusing following SARS-CoV-2 spike imprinting
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  84. www.embopress.org www.embopress.org
    Ketogenic HMG-CoA lyase and its product β-hydroxybutyrate promote pancreatic cancer progression
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    Tumour cell-activated platelets modulate the immunological activity of CD4+, CD8+, and NK cells, which is efficiently antagonized by heparin
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      DOI: 10.1007/s00262-022-03186-5

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  86. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Translational Physiology: Extracellular flux analyses reveal differences in mitochondrial PBMC metabolism between high-fit and low-fit females
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  87. www.sciencedirect.com www.sciencedirect.com
    A cholinergic neuroskeletal interface promotes bone formation during postnatal growth and exercise
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    Deletion of STAT3 from Foxd1 cell population protects mice from kidney fibrosis by inhibiting pericytes trans-differentiation and migration
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  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Local treatment of a pediatric osteosarcoma model with a 4-1BBL armed oncolytic adenovirus results in an antitumor effect and leads to immune memory
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      DOI: 10.1158/1535-7163.MCT-21-0565

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  90. aacrjournals.org aacrjournals.org
    MYC Inhibition Halts Metastatic Breast Cancer Progression by Blocking Growth, Invasion, and Seeding
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  91. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Cytidine Deaminase APOBEC3A Regulates PD-L1 Expression in Cancer Cells in a JNK/c-JUN-dependent Manner
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nonsense-mediated RNA decay is a unique vulnerability of cancer cells harboring SF3B1 or U2AF1 mutations
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  93. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Activating Mucosal-Associated Invariant T cells Induces a Broad Antitumor Response
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      DOI: 10.1158/2326-6066.CIR-20-0925

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    Immunodepletion of MDSC by AMV564, a novel bivalent, bispecific CD33/CD3 T cell engager, ex vivo in MDS and melanoma
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  95. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Zinc finger protein Zfp335 controls early T-cell development and survival through β-selection-dependent and -independent mechanisms
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      DOI: 10.7554/eLife.75508

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    Myeloperoxidase exerts anti-tumor activity in glioma after radiotherapy
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  97. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Respiratory mucosal delivery of next-generation COVID-19 vaccine provides robust protection against both ancestral and variant strains of SARS-CoV-2
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    Nicotinamide Breaks Effector CD8 T cell Responses by Targeting mTOR Signaling
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Thymocytes trigger self-antigen-controlling pathways in immature medullary thymic epithelial stages
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      DOI: 10.7554/eLife.69982

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  100. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The Conditioning Lesion Response in Dorsal Root Ganglion Neurons Is Inhibited in Oncomodulin Knock-Out Mice
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      DOI: 10.1523/ENEURO.0477-21.2022

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    Structure-guided changes at the V2 apex of HIV-1 clade C trimer enhance elicitation of autologous neutralizing and broad V1V2-scaffold antibodies
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    Follicular T Cells Optimize the Germinal Center Response to SARS-CoV-2 Protein Vaccination in Mice
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  103. Feb 2022
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    Protocol to identify and monitor key mutations of broadly neutralizing antibody lineages following sequential immunization of Ig-humanized mice
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    EBF1 nuclear repositioning instructs chromatin refolding to promote therapy resistance in T leukemic cells
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  106. elifesciences.org elifesciences.org
    Recapitulating human cardio-pulmonary co-development using simultaneous multilineage differentiation of pluripotent stem cells
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      DOI: 10.7554/eLife.67872

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  107. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Etoposide-induced DNA damage is increased in p53 mutants: identification of ATR and other genes that influence effects of p53 mutations on Top2-induced cytotoxicity
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      DOI: 10.18632/oncotarget.28195

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  108. elifesciences.org elifesciences.org
    Repression of hypoxia-inducible factor-1 contributes to increased mitochondrial reactive oxygen species production in diabetes
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      DOI: 10.7554/eLife.70714

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  109. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Single-cell analysis of human glioma and immune cells identifies S100A4 as an immunotherapy target
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      DOI: 10.1038/s41467-022-28372-y

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    Aire suppresses CTLA-4 expression from the thymic stroma to control autoimmunity
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    Sesquiterpene Lactones Potentiate Olaparib-Induced DNA Damage in p53 Wildtype Cancer Cells
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      DOI: 10.3390/ijms23031116

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    The light chain of the L9 antibody is critical for binding circumsporozoite protein minor repeats and preventing malaria
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    Substrate rigidity dictates colorectal tumorigenic cell stemness and metastasis via CRAD-dependent mechanotransduction
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  114. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A zebrafish embryo screen utilizing gastrulation identifies the HTR2C inhibitor pizotifen as a suppressor of EMT-mediated metastasis
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      DOI: 10.7554/eLife.70151

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  115. insight.jci.org insight.jci.org
    Mosaic loss of chromosome Y promotes leukemogenesis and clonal hematopoiesis
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    Immune translational control by CPEB4 regulates intestinal inflammation resolution and colorectal cancer development
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    An adjuvant strategy enabled by modulation of the physical properties of microbial ligands expands antigen immunogenicity
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    SARS-CoV-2 vaccination induces immunological T cell memory able to cross-recognize variants from Alpha to Omicron
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  119. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    NKG7 is a T-cell intrinsic therapeutic target for improving antitumor cytotoxicity and cancer immunotherapy
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      DOI: 10.1158/2326-6066.CIR-21-0539

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  120. link.springer.com link.springer.com
    When left does not seem right: epigenetic and bioelectric differences between left- and right-sided breast cancer
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      DOI: 10.1186/s10020-022-00440-5

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  121. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development of a Novel Anti-CD19 CAR Containing a Fully Human scFv and Three Costimulatory Domains
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      DOI: 10.3389/fonc.2021.802876

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    Isolation of myenteric and submucosal plexus from mouse gastrointestinal tract and subsequent flow cytometry and immunofluorescence
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      DOI: 10.1016/j.xpro.2022.101157

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    Antibody bivalency improves antiviral efficacy by inhibiting virion release independently of Fc gamma receptors
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      DOI: 10.1016/j.celrep.2022.110303

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    Stress conditions promote Leishmania hybridization in vitro marked by expression of the ancestral gamete fusogen HAP2 as revealed by single-cell RNA-seq
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  126. Jan 2022
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    Primary germinal center-resident T follicular helper cells are a physiologically distinct subset of CXCR5hiPD-1hi T follicular helper cells
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    Mechanosensitive Channel Piezo1 Induces Cell Apoptosis in Pancreatic Cancer by Ultrasound with Microbubbles
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    Macrophages activated by hepatitis B virus have distinct metabolic profiles and suppress the virus via IL-1β to downregulate PPARα and FOXO3
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    Notch2 Increases the Resistance to Venetoclax-Induced Apoptosis in Chronic Lymphocytic Leukemia B Cells by Inducing Mcl-1
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    Autologous humanized mouse models of iPSC-derived tumors enable characterization and modulation of cancer-immune cell interactions
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    Role of distinct fibroblast lineages and immune cells in dermal repair following UV radiation-induced tissue damage
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    De novo synthesized polyunsaturated fatty acids operate as both host immunomodulators and nutrients for Mycobacterium tuberculosis
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    p38 Inhibition Decreases Tau Toxicity in Microglia and Improves Their Phagocytic Function
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    SARS-CoV-2 spike protein induces inflammation via TLR2-dependent activation of the NF-κB pathway
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    Normalization of cholesterol metabolism in spinal microglia alleviates neuropathic pain
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    Regulation of positive and negative selection and TCR signaling during thymic T cell development by capicua
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    Inflammasome activation leads to cDC1-independent cross-priming of CD8 T cells by epithelial cell-derived antigen
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    Bisphosphonate drugs have actions in the lung and inhibit the mevalonate pathway in alveolar macrophages
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    Inhibition of transcription factor NFAT activity in activated platelets enhances their aggregation and exacerbates gram-negative bacterial septicemia
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    mRNA-based COVID-19 vaccine boosters induce neutralizing immunity against SARS-CoV-2 Omicron variant
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    Structural basis and mode of action for two broadly neutralizing antibodies against SARS-CoV-2 emerging variants of concern
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    The enteric pathogen Cryptosporidium parvum exports proteins into the cytosol of the infected host cell
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    Regulatory T cell transcriptomic reprogramming characterizes adverse events by checkpoint inhibitors in solid tumors
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    Naive and memory CD4+ T cell subsets can contribute to the generation of human Tfh cells
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    CXCL4 drives fibrosis by promoting several key cellular and molecular processes
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    AMPK-PERK axis represses oxidative metabolism and enhances apoptotic priming of mitochondria in acute myeloid leukemia
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  151. Dec 2021
  152. elifesciences.org elifesciences.org
    IL-2/JES6-1 mAb complexes dramatically increase sensitivity to LPS through IFN-γ production by CD25+Foxp3- T cells
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    Intracellular IL-32 regulates mitochondrial metabolism, proliferation, and differentiation of malignant plasma cells
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    The ADAM17-directed Inhibitory Antibody MEDI3622 Antagonizes Radiotherapy-induced VEGF Release and Sensitizes Non–Small Cell Lung Cancer for RadiotherapyADAM17-mediated Radioresistance
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    Opposing Effects of Granulocyte Colony-Stimulating Factor on the Initiation and Progression of Breast Cancer Bone Metastases
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    Engagement of the costimulatory molecule ICOS in tissues promotes establishment of CD8+ tissue-resident memory T cells
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    Wnt signaling mediates acquisition of blood–brain barrier properties in naïve endothelium derived from human pluripotent stem cells
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  158. elifesciences.org elifesciences.org
    Hydrogen sulfide blocks HIV rebound by maintaining mitochondrial bioenergetics and redox homeostasis
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    Orthotopic T-cell receptor replacement in primary human T cells using CRISPR-Cas9-mediated homology-directed repair
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    A recombinant protein containing influenza viral conserved epitopes and superantigen induces broad-spectrum protection
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    lncRNA BORG:TRIM28 Complexes Drive Metastatic Progression by Inducing α6 Integrin/CD49f Expression in Breast Cancer Stem Cells
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    Endothelial Cell CD36 Reduces Atherosclerosis and Controls Systemic Metabolism
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  163. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Secretory IgA and T cells targeting SARS-CoV-2 spike protein are transferred to the breastmilk upon mRNA vaccination
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  164. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Histone deacetylase 3 represses cholesterol efflux during CD4+ T-cell activation
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    Chronic calcium signaling in IgE+ B cells limits plasma cell differentiation and survival
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    Molecular features underlying differential SHP1/SHP2 binding of immune checkpoint receptors
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  167. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Chronic adrenergic stress contributes to metabolic dysfunction and an exhausted phenotype in T cells in the tumor microenvironment
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    A heparan-sulfate-bearing syndecan-1 glycoform is a distinct surface marker for intra-tumoral myeloid-derived suppressor cells
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  169. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protein kinase Cδ is essential for the IgG response against T-cell-independent type 2 antigens and commensal bacteria
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  170. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting conserved N-glycosylation blocks SARS-CoV-2 variant infection in vitro
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    Pre-existing chromatin accessibility and gene expression differences among naive CD4+ T cells influence effector potential
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    Altered H3 histone acetylation impairs high-fidelity DNA repair to promote cerebellar degeneration in spinocerebellar ataxia type 7
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    Vectored antibody gene delivery restores host B and T cell control of persistent viral infection
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  174. Nov 2021
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    CXCL10 chemokine regulates heterogeneity of the CD8+ T cell response and viral set point during chronic infection
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    A novel, ataxic mouse model of ataxia telangiectasia caused by a clinically relevant nonsense mutation
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  177. mct.aacrjournals.org mct.aacrjournals.org
    Simultaneously Combined Cancer Cell- and CTLA4-Targeted NIR-PIT Causes a Synergistic Treatment Effect in Syngeneic Mouse Models
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    Differentiation of fetal hematopoietic stem cells requires ARID4B to restrict autocrine KITLG/KIT-Src signaling
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    Fragmentation of tissue-resident macrophages during isolation confounds analysis of single-cell preparations from mouse hematopoietic tissues
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    Novel protocol for the isolation of highly purified neonatal murine microglia and astrocytes
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  182. www.nature.com www.nature.com
    CHD5 inhibits metastasis of neuroblastoma
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  183. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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  184. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The mitochondrial iron transporter ABCB7 is required for B cell development, proliferation, and class switch recombination in mice
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  185. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Circulating Immunosuppressive Regulatory T Cells Predict Risk of Incident Cutaneous Squamous Cell Carcinoma
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  186. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Intraocular dendritic cells characterize HLA-B27-associated acute anterior uveitis
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  187. febs.onlinelibrary.wiley.com febs.onlinelibrary.wiley.com
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    Topoisomerase 1 activity during mitotic transcription favors the transition from mitosis to G1
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    Hif-1a suppresses ROS-induced proliferation of cardiac fibroblasts following myocardial infarction
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    A Cell-Based Platform for the Investigation of Immunoproteasome Subunit β5i Expression and Biology of β5i-Containing Proteasomes
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    Acsbg1-dependent mitochondrial fitness is a metabolic checkpoint for tissue Treg cell homeostasis
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    The cell-surface 5′-nucleotidase CD73 defines a functional T memory cell subset that declines with age
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    Mitochondrial respiration restricts Listeria monocytogenes infection by slowing down host cell receptor recycling
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    DDK/Hsk1 phosphorylates and targets fission yeast histone deacetylase Hst4 for degradation to stabilize stalled DNA replication forks
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    Zinc-dependent histone deacetylases drive neutrophil extracellular trap formation and potentiate local and systemic inflammation
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    Reduced mitochondrial respiration in T cells of patients with major depressive disorder
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    3D biomimetic platform reveals the first interactions of the embryo and the maternal blood vessels
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    6-Phosphogluconate dehydrogenase (6PGD), a key checkpoint in reprogramming of regulatory T cells metabolism and function
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  199. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Glut1 expression in tumor-associated neutrophils promotes lung cancer growth and resistance to radiotherapy
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  200. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    CRISPR Screening of CAR T Cells and Cancer Stem Cells Reveals Critical Dependencies for Cell-Based Therapies
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  201. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Original research: Interleukin-30 feeds breast cancer stem cells via CXCL10 and IL23 autocrine loops and shapes immune contexture and host outcome
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    Targeting glioblastoma signaling and metabolism with a re-purposed brain-penetrant drug
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  203. Oct 2021
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    Optimized protocol for naive human pluripotent stem cell-derived trophoblast induction
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  205. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HES1 protein oscillations are necessary for neural stem cells to exit from quiescence
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    A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
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