2,555 Matching Annotations
  1. Sep 2022
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    Ceramide induces macrophage migration inhibitory factor -mediated parthanatos in mouse neurons by increasing ROS levels
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    Target protein localization and its impact on PROTAC-mediated degradation
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    Na/K-ATPase Suppresses LPS-Induced Pro-Inflammatory Signaling Through Lyn
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    GINS1 promotes the proliferation and migration of glioma cells through USP15-mediated deubiquitination of TOP2A
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    ncbi.nlm.nih.gov/pmc/articles/PMC9440292/
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    Methionine metabolism controls the B cell EBV epigenome and viral latency
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    Choroid plexus-CSF-targeted antioxidant therapy protects the brain from toxicity of cancer chemotherapy
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    Hepatic cytochrome P450 8B1 and cholic acid potentiate intestinal epithelial injury in colitis by suppressing intestinal stem cell renewal
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  9. Aug 2022
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    Npas3 deficiency impairs cortical astrogenesis and induces autistic-like behaviors
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    PH domain-mediated autoinhibition and oncogenic activation of Akt
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    Interleukin-27 signaling serves as an immunological checkpoint for innate cytotoxic cells to promote hepatocellular carcinoma
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    Notch Signaling Induced by Endoplasmic Reticulum Stress Regulates Cumulus-Oocyte Complex Expansion in Polycystic Ovary Syndrome
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    Knockout of Sirt2 alleviates traumatic brain injury in mice
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    The Alzheimer’s disease-associated gene TREML2 modulates inflammation by regulating microglia polarization and NLRP3 inflammasome activation
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    Visual-area-specific tonic modulation of GABA release by endocannabinoids sets the activity and coordination of neocortical principal neurons
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    Internal checkpoint regulates T cell neoantigen reactivity and susceptibility to PD1 blockade
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    Inhibition of human macrophage activation via pregnane neurosteroid interactions with toll-like receptors: Sex differences and structural requirements
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    Identification of Src as a Therapeutic Target in Oesophageal Adenocarcinoma through Functional Genomic and High-Throughput Drug Screening Approaches
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    SARS-CoV-2 Spike N-Terminal Domain modulates TMPRSS2-dependent viral entry and fusogenicity
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    STK25 inhibits PKA signaling by phosphorylating PRKAR1A
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    Limbal BCAM expression identifies a proliferative progenitor population capable of holoclone formation and corneal differentiation
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    Integrative Profiling of Amyotrophic Lateral Sclerosis Lymphoblasts Identifies Unique Metabolic and Mitochondrial Disease Fingerprints
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    Obesity and Fatty Acids Promote Mitochondrial Translocation of STAT3 Through ROS-Dependent Mechanisms
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    Cardiac fibroblast heat shock protein 47 aggravates cardiac fibrosis post myocardial ischemia–reperfusion injury by encouraging ubiquitin specific peptidase 10 dependent Smad4 deubiquitination
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    Combination of type I and type II MET tyrosine kinase inhibitors as therapeutic approach to prevent resistance
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    Transcription Elongation Machinery Is a Druggable Dependency and Potentiates Immunotherapy in Glioblastoma Stem Cells
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  34. Jul 2022
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    Efficacy of Combined Use of Everolimus and Second-Generation Pan-EGRF Inhibitors in KRAS Mutant Non-Small Cell Lung Cancer Cell Lines
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    Membrane Targeting and GTPase Activity of Rab7 Are Required for Its Ubiquitination by RNF167
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    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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    Succinylation Inhibits the Enzymatic Hydrolysis of the Extracellular Matrix Protein Fibrillin 1 and Promotes Gastric Cancer Progression
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    Tumoral microenvironment prevents de novo asparagine biosynthesis in B cell lymphoma, regardless of ASNS expression
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    Trimeric Receptor Binding Domain of SARS-CoV-2 Acts as a Potent Inhibitor of ACE2 Receptor-Mediated Viral Entry
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    Mitotic SENP3 activation couples with cGAS signaling in tumor cells to stimulate anti-tumor immunity
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    Phloretin enhances autophagy by impairing AKT activation and inducing JNK-Beclin-1 pathway activation
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    TREM2-induced activation of microglia contributes to synaptic integrity in cognitively intact aged individuals with Alzheimer's neuropathology
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    Engineering chimeric antigen receptor neutrophils from human pluripotent stem cells for targeted cancer immunotherapy
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    Long non-coding RNA EVADR induced by Fusobacterium nucleatum infection promotes colorectal cancer metastasis
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    PTEN and LKB1 are differentially required in Gli1-expressing mesenchymal cells to suppress gastrointestinal polyposis
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    Protein signaling in response to ex vivo dynamic contractions is independent of training status in rat skeletal muscle
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    Oxidized DNA fragments exit mitochondria via mPTP- and VDAC-dependent channels to activate NLRP3 inflammasome and interferon signaling
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    In vitro modeling of amyotrophic lateral sclerosis with induced pluripotent stem cell technology-derived cell line ORIONi002-A
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    Pulmonary surfactants and the respiratory-renal connection in steroid-sensitive nephrotic syndrome of childhood
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    Inhibition of SIRT2 promotes APP acetylation and ameliorates cognitive impairment in APP/PS1 transgenic mice
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    A specialized Hsp90 co-chaperone network regulates steroid hormone receptor response to ligand
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    A ROS-dependent mechanism promotes CDK2 phosphorylation to drive progression through S phase
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    Beta-blockers disrupt mitochondrial bioenergetics and increase radiotherapy efficacy independently of beta-adrenergic receptors in medulloblastoma
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    The Combination of Δ9-Tetrahydrocannabinol and Cannabidiol Suppresses Mitochondrial Respiration of Human Glioblastoma Cells via Downregulation of Specific Respiratory Chain Proteins
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    Genome-Wide CRISPR Screening Identifies DCK and CCNL1 as Genes That Contribute to Gemcitabine Resistance in Pancreatic Cancer
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    Mesenchymal stromal cells cultured in physiological conditions sustain citrate secretion with glutamate anaplerosis
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    Neoadjuvant chemotherapy induces genomic and transcriptomic changes in ovarian cancer
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    Aberrant expression and subcellular localization of ECT2 drives colorectal cancer progression and growth
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    Cholinergic interneuron inhibition potentiates corticostriatal transmission in direct medium spiny neurons and rescues motor learning in parkinsonism
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    FKBP11 rewires UPR signaling to promote glucose homeostasis in type 2 diabetes and obesity
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    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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    The mTORC1-SLC4A7 axis stimulates bicarbonate import to enhance de novo nucleotide synthesis
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    Protocol for assessing ex vivo lipolysis of murine adipose tissue
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  68. Jun 2022
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    Replication stress triggered by nucleotide pool imbalance drives DNA damage and cGAS-STING pathway activation in NAFLD
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    Flattening of circadian glucocorticoid oscillations drives acute hyperinsulinemia and adipocyte hypertrophy
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    Neutrophil Extracellular Traps Mediate Acute Liver Failure in Regulation of miR-223/neutrophil Elastase Signaling in Mice
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    Actions of Parathyroid Hormone Ligand Analogs in Humanized PTH1R Knock-In Mice
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    Lamotrigine protects against cognitive deficits, synapse... : Neural Regeneration Research
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    The STING1-MYD88 complex drives ACOD1/IRG1 expression and function in lethal innate immunity
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    mafba and mafbb differentially regulate lymphatic endothelial cell migration in topographically distinct manners
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    TCF-1 promotes chromatin interactions across topologically associating domains in T cell progenitors
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    Combinatorial ASO-mediated therapy with low dose SMN and the protective modifier Chp1 is not sufficient to ameliorate SMA pathology hallmarks
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    Parsing the role of NSP1 in SARS-CoV-2 infection
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    Comprehensive surfaceome profiling to identify and validate novel cell-surface targets in osteosarcoma
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    YAP1 maintains active chromatin state in head and neck squamous cell carcinomas that promotes tumorigenesis through cooperation with BRD4
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    Vps33B controls Treg cell suppressive function through inhibiting lysosomal nutrient sensing complex-mediated mTORC1 activation
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    Satellite cell-specific deletion of Cipc alleviates myopathy in mdx mice
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    Identification of metabolic pathways underlying FGF1 and CHIR99021-mediated cardioprotection
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    CPEB3-dependent increase in GluA2 subunits impairs excitatory transmission onto inhibitory interneurons in a mouse model of fragile X
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    Direct epitranscriptomic regulation of mammalian translation initiation through N4-acetylcytidine
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    Inhibition of ATP-citrate lyase improves NASH, liver fibrosis, and dyslipidemia
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    PDGF signaling inhibits mitophagy in glioblastoma stem cells through N6-methyladenosine
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