2,057 Matching Annotations
  1. Apr 2021
  2. www.sciencedirect.com www.sciencedirect.com
    A membrane arm of mitochondrial complex I sufficient to promote respirasome formation
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    sciencedirect.com/science/article/pii/S2211124721002771
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    The dystonia gene THAP1 controls DNA double-strand break repair choice
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    sciencedirect.com/science/article/pii/S109727652100229X
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    Loss of LUC7L2 and U1 snRNP subunits shifts energy metabolism from glycolysis to OXPHOS
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    cell.com/molecular-cell/fulltext/S1097-2765(21)00143-X
  5. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Investigating oligodendrocyte connexins: Heteromeric interactions between Cx32 and mutant or wild‐type forms of Cx47 do not contribute to or modulate gap junction function
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    onlinelibrary.wiley.com/doi/full/10.1002/glia.23999
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    Functional interrogation of DNA damage response variants with base editing screens
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    sciencedirect.com/science/article/pii/S0092867421000842
  7. www.cell.com www.cell.com
    β-propeller proteins WDR45 and WDR45B regulate autophagosome maturation into autolysosomes in neural cells
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    cell.com/current-biology/abstract/S0960-9822(21)00146-9
  8. www.jneurosci.org www.jneurosci.org
    Neuronal Nitric Oxide Synthase in Nucleus Accumbens Specifically Mediates Susceptibility to Social Defeat Stress through Cyclin-Dependent Kinase 5
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    jneurosci.org/content/41/11/2523
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    Serine metabolism antagonizes antiviral innate immunity by preventing ATP6V0d2-mediated YAP lysosomal degradation
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    sciencedirect.com/science/article/pii/S1550413121001133
  10. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GREB1: An evolutionarily conserved protein with a glycosyltransferase domain links ERα glycosylation and stability to cancer
    1
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    ncbi.nlm.nih.gov/pmc/articles/PMC7968844/
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    Asterix/Gtsf1 links tRNAs and piRNA silencing of retrotransposons
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    sciencedirect.com/science/article/pii/S221112472100228X
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    UPF1 reduces C9orf72 HRE-induced neurotoxicity in the absence of nonsense-mediated decay dysfunction
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    sciencedirect.com/science/article/pii/S2211124721002394
  13. Mar 2021
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A nuclear-based quality control pathway for non-imported mitochondrial proteins
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    ncbi.nlm.nih.gov/pmc/articles/PMC7993989/
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    Human MC4R variants affect endocytosis, trafficking and dimerization revealing multiple cellular mechanisms involved in weight regulation
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    sciencedirect.com/science/article/pii/S2211124721001765
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    H3.3-K27M drives neural stem cell-specific gliomagenesis in a human iPSC-derived model
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    sciencedirect.com/science/article/pii/S1535610821000490
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    Phosphorylation-regulated HMGA1a-P53 interaction unveils the function of HMGA1a acidic tail phosphorylations via synthetic proteins
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    sciencedirect.com/science/article/pii/S2451945621000076
  18. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Basis of specificity for a conserved and promiscuous chromatin remodeling protein
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    ncbi.nlm.nih.gov/pmc/articles/PMC7968928/
  19. elifesciences.org elifesciences.org
    TWIST1 and chromatin regulatory proteins interact to guide neural crest cell differentiation
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    elifesciences.org/articles/62873
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    Modeling the complete kinetics of coxsackievirus B3 reveals human determinants of host-cell feedback
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    sciencedirect.com/science/article/pii/S2405471221000788
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    Parkin is an E3 ligase for the ubiquitin-like modifier FAT10, which inhibits Parkin activation and mitophagy
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    sciencedirect.com/science/article/pii/S2211124721001716
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    A genome-wide CRISPR screen identifies UFMylation and TRAMP-like complexes as host factors required for hepatitis A virus infection
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    sciencedirect.com/science/article/pii/S221112472100173X
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    DSB repair pathway choice is regulated by recruitment of 53BP1 through cell cycle-dependent regulation of Sp1
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    sciencedirect.com/science/article/pii/S2211124721001546
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    Functional proteomics protocol for the identification of interaction partners in Tetrahymena thermophila
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    sciencedirect.com/science/article/pii/S2666166721000691
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    CA10 regulates neurexin heparan sulfate addition via a direct binding in the secretory pathway
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    embopress.org/doi/abs/10.15252/embr.202051349
  26. www.cell.com www.cell.com
    The phytochemical hyperforin triggers thermogenesis in adipose tissue via a Dlat-AMPK signaling axis to curb obesity
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    cell.com/cell-metabolism/fulltext/S1550-4131(21)00063-2
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    Ectopically expressed olfactory receptors OR51E1 and OR51E2 suppress proliferation and promote cell death in a prostate cancer cell line
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    sciencedirect.com/science/article/pii/S0021925821002490
  28. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Negative feedback couples Hippo pathway activation with Kibra degradation independent of Yorkie-mediated transcription
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    ncbi.nlm.nih.gov/pmc/articles/PMC7895526/
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    Spliceosome-targeted therapies trigger an antiviral immune response in triple-negative breast cancer
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    sciencedirect.com/science/article/pii/S0092867420317530
  30. Feb 2021
  31. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis
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    ncbi.nlm.nih.gov/pmc/articles/PMC7786221/
  32. www.sciencedirect.com www.sciencedirect.com
    Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency
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    sciencedirect.com/science/article/pii/S109727652030887X
  33. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The RNA-binding protein SFPQ preserves long-intron splicing and regulates circRNA biogenesis in mammals
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    ncbi.nlm.nih.gov/pmc/articles/PMC7819710/
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    Acetyl-CoA Synthetase 2: A Critical Linkage in Obesity-Induced Tumorigenesis in Myeloma
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    sciencedirect.com/science/article/pii/S1550413120306665
  35. www.pnas.org www.pnas.org
    The Ligand of Ate1 is intrinsically disordered and participates in nucleolar phase separation regulated by Jumonji Domain Containing 6
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    pnas.org/content/118/1/e2015887118
  36. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification of ubiquitin Ser57 kinases regulating the oxidative stress response in yeast
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    ncbi.nlm.nih.gov/pmc/articles/PMC7647399/
  37. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Neuroprotective activity of ursodeoxycholic acid in CHMP2BIntron5 models of frontotemporal dementia
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    ncbi.nlm.nih.gov/pmc/articles/PMC7491204/
  38. www.cell.com www.cell.com
    Ribosome Collision Is Critical for Quality Control during No-Go Decay
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    cell.com/molecular-cell/abstract/S1097-2765(17)30616-0
  39. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    α-synuclein strains that cause distinct pathologies differentially inhibit proteasome
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    ncbi.nlm.nih.gov/pmc/articles/PMC7406352/
  40. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Serotonin signaling by maternal neurons upon stress ensures progeny survival
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    ncbi.nlm.nih.gov/pmc/articles/PMC7237211/
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    Human DDK rescues stalled forks and counteracts checkpoint inhibition at unfired origins to complete DNA replication
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    sciencedirect.com/science/article/pii/S1097276521000046
  42. www.cell.com www.cell.com
    Negative regulation of AMPK signaling by high glucose via E3 ubiquitin ligase MG53
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30900-X
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    CRTC1/MAML2 directs a PGC-1α-IGF-1 circuit that confers vulnerability to PPARγ inhibition
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    sciencedirect.com/science/article/pii/S2211124721000814
  44. www.cell.com www.cell.com
    ZNF410 Uniquely Activates the NuRD Component CHD4 to Silence Fetal Hemoglobin Expression
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30784-X
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    CARM1 regulates replication fork speed and stress response by stimulating PARP1
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    sciencedirect.com/science/article/pii/S1097276520309023
  46. www.molbiolcell.org www.molbiolcell.org
    Vezatin is required for the maturation of the neuromuscular synapse
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    molbiolcell.org/doi/abs/10.1091/mbc.E19-06-0313
  47. www.cell.com www.cell.com
    Loss of Human TGS1 Hypermethylase Promotes Increased Telomerase RNA and Telomere Elongation
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    cell.com/cell-reports/abstract/S2211-1247(20)30013-9
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    Competition between PRC2.1 and 2.2 subcomplexes regulates PRC2 chromatin occupancy in human stem cells
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    sciencedirect.com/science/article/pii/S1097276520308868
  49. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    SNPC-1.3 is a sex-specific transcription factor that drives male piRNA expression in C. elegans
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    ncbi.nlm.nih.gov/pmc/articles/PMC7884074/
  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Dimerisation of the PICTS complex via LC8/Cut-up drives co-transcriptional transposon silencing in Drosophila
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    ncbi.nlm.nih.gov/pmc/articles/PMC7861614/
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    Ctdnep1 and Eps8L2 regulate dorsal actin cables for nuclear positioning during cell migration
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    sciencedirect.com/science/article/pii/S0960982221000403
  52. elifesciences.org elifesciences.org
    Diverse viral proteases activate the NLRP1 inflammasome
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    elifesciences.org/articles/60609
  53. www.sciencedirect.com www.sciencedirect.com
    Semi-automated single-molecule microscopy screening of fast-dissociating specific antibodies directly from hybridoma cultures
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    sciencedirect.com/science/article/pii/S2211124721000218
  54. academic.oup.com academic.oup.com
    The nascent polypeptide in the 60S subunit determines the Rqc2-dependency of ribosomal quality control
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    academic.oup.com/nar/advance-article/doi/10.1093/nar/gkab005/6123380
  55. Jan 2021
  56. www.sciencedirect.com www.sciencedirect.com
    ORF3a of the COVID-19 virus SARS-CoV-2 blocks HOPS complex-mediated assembly of the SNARE complex required for autolysosome formation
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    sciencedirect.com/science/article/pii/S1534580720310169
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    Proton-activated chloride channel PAC regulates endosomal acidification and transferrin receptor-mediated endocytosis
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    sciencedirect.com/science/article/pii/S2211124720316727
  58. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Ecd promotes U5 snRNP maturation and Prp8 stability
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    ncbi.nlm.nih.gov/pmc/articles/PMC7897482/
  59. www.micropublication.org www.micropublication.org
    Purified Bighead protein efficiently promotes head development in the South African clawed frog, Xenopus laevis
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    micropublication.org/journals/biology/micropub-biology-000347/
  60. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Therapeutic genetic variation revealed in diverse Hsp104 homologs
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    ncbi.nlm.nih.gov/pmc/articles/PMC7785292/
  61. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Yeast Nuak1 phosphorylates histone H3 threonine 11 in low glucose stress by the cooperation of AMPK and CK2 signaling
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    ncbi.nlm.nih.gov/pmc/articles/PMC7781599/
  62. www.embopress.org www.embopress.org
    A microtubule‐LUZP1 association around tight junction promotes epithelial cell apical constriction
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    embopress.org/doi/abs/10.15252/embj.2020104712
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    Failure to Degrade CAT-Tailed Proteins Disrupts Neuronal Morphogenesis and Cell Survival
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    sciencedirect.com/science/article/pii/S2211124720315886
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    Piwil1 Regulates Glioma Stem Cell Maintenance and Glioblastoma Progression
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    sciencedirect.com/science/article/pii/S2211124720315114
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    DNA and RNA Cleavage Complexes and Repair Pathway for TOP3B RNA- and DNA-Protein Crosslinks
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    sciencedirect.com/science/article/pii/S2211124720315588
  66. Dec 2020
  67. www.sciencedirect.com www.sciencedirect.com
    Bistable, Biphasic Regulation of PP2A-B55 Accounts for the Dynamics of Mitotic Substrate Phosphorylation
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    sciencedirect.com/science/article/pii/S0960982220317711
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    TREX2 Exonuclease Causes Spontaneous Mutations and Stress-Induced Replication Fork Defects in Cells Expressing RAD51K133A
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    sciencedirect.com/science/article/pii/S2211124720315321
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    An RNA Repair Operon Regulated by Damaged tRNAs
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    sciencedirect.com/science/article/pii/S2211124720315163
  70. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    AKAP6 orchestrates the nuclear envelope microtubule-organizing center by linking golgi and nucleus via AKAP9
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    ncbi.nlm.nih.gov/pmc/articles/PMC7725499/
  71. www.sciencedirect.com www.sciencedirect.com
    Nuclear cGAS Functions Non-canonically to Enhance Antiviral Immunity via Recruiting Methyltransferase Prmt5
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    sciencedirect.com/science/article/pii/S2211124720314790
  72. www.cell.com www.cell.com
    Hyperactive CDK2 Activity in Basal-like Breast Cancer Imposes a Genome Integrity Liability that Can Be Exploited by Targeting DNA Polymerase ε
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    cell.com/molecular-cell/fulltext/S1097-2765(20)30723-1
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    BPS Publications
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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15060
  74. www.embopress.org www.embopress.org
    Human CST complex protects stalled replication forks by directly blocking MRE11 degradation of nascent‐strand DNA
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    embopress.org/doi/abs/10.15252/embj.2019103654
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    TRIM11 Prevents and Reverses Protein Aggregation and Rescues a Mouse Model of Parkinson’s Disease
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    sciencedirect.com/science/article/pii/S2211124720314078
  76. Nov 2020
  77. www.sciencedirect.com www.sciencedirect.com
    ISRIB Blunts the Integrated Stress Response by Allosterically Antagonising the Inhibitory Effect of Phosphorylated eIF2 on eIF2B
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    sciencedirect.com/science/article/pii/S1097276520307383
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    Essentiality of CENP-A Depends on Its Binding Mode to HJURP
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    sciencedirect.com/science/article/pii/S2211124720313772
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    BUBR1 Pseudokinase Domain Promotes Kinetochore PP2A-B56 Recruitment, Spindle Checkpoint Silencing, and Chromosome Alignment
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    sciencedirect.com/science/article/pii/S2211124720313863
  80. www.cell.com www.cell.com
    An Aphid-Secreted Salivary Protease Activates Plant Defense in Phloem
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    cell.com/current-biology/abstract/S0960-9822(20)31351-8
  81. www.cell.com www.cell.com
    Formation of the CenH3-Deficient Holocentromere in Lepidoptera Avoids Active Chromatin
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    cell.com/current-biology/abstract/S0960-9822(20)31448-2
  82. www.sciencedirect.com www.sciencedirect.com
    A Systematic Protein Turnover Map for Decoding Protein Degradation
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    sciencedirect.com/science/article/pii/S221112472031367X
  83. www.sciencedirect.com www.sciencedirect.com
    The Proteomic Landscape of Centromeric Chromatin Reveals an Essential Role for the Ctf19CCAN Complex in Meiotic Kinetochore Assembly
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    sciencedirect.com/science/article/pii/S0960982220315293
  84. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Atg43 tethers isolation membranes to mitochondria to promote starvation-induced mitophagy in fission yeast
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    ncbi.nlm.nih.gov/pmc/articles/PMC7609059/
  85. www.sciencedirect.com www.sciencedirect.com
    Auxin-Regulated Reversible Inhibition of TMK1 Signaling by MAKR2 Modulates the Dynamics of Root Gravitropism
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    sciencedirect.com/science/article/pii/S0960982220315153
  86. pubmed.ncbi.nlm.nih.gov pubmed.ncbi.nlm.nih.gov
    GDF6-CD99 Signaling Regulates Src and Ewing Sarcoma Growth
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    pubmed.ncbi.nlm.nih.gov/33147457/
  87. www.sciencedirect.com www.sciencedirect.com
    Type-IInterferon-Inducible SERTAD3 Inhibits Influenza A Virus Replication by Blocking the Assembly of Viral RNA Polymerase Complex
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    sciencedirect.com/science/article/pii/S2211124720313310
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    Defining Essential Enhancers for Pluripotent Stem Cells Using a Features-Oriented CRISPR-Cas9 Screen
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    sciencedirect.com/science/article/pii/S2211124720312985
  89. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fat Body p53 Regulates Systemic Insulin Signaling and Autophagy under Nutrient Stress via Drosophila Upd2 Repression
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    ncbi.nlm.nih.gov/pmc/articles/PMC9036415/
  90. Oct 2020
  91. www.sciencedirect.com www.sciencedirect.com
    The Obesity-Susceptibility Gene TMEM18 Promotes Adipogenesis through Activation of PPARG
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    sciencedirect.com/science/article/pii/S2211124720312845
  92. www.sciencedirect.com www.sciencedirect.com
    Functional Diversification of SRSF Protein Kinase to Control Ubiquitin-Dependent Neurodevelopmental Signaling
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    sciencedirect.com/science/article/pii/S1534580720307577
  93. elifesciences.org elifesciences.org
    Gli3 utilizes Hand2 to synergistically regulate tissue-specific transcriptional networks
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    elifesciences.org/articles/56450
  94. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    TASOR is a pseudo-PARP that directs HUSH complex assembly and epigenetic transposon control
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