2,392 Matching Annotations
  1. Dec 2022
  2. www.embopress.org www.embopress.org
    IMPDH inhibition activates TLR-VCAM1 pathway and suppresses the development of MLL-fusion leukemia
    1
    1. scibot 02 Dec 2022
      RRID:Addgene_12260

      DOI: 10.15252/emmm.202115631

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    embopress.org/doi/10.15252/emmm.202115631
  3. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Systematic discovery and functional dissection of enhancers needed for cancer cell fitness and proliferation
    1
    1. scibot 02 Dec 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2022.111630

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    ncbi.nlm.nih.gov/pmc/articles/PMC9687083/
  4. www.sciencedirect.com www.sciencedirect.com
    BRAFV600E in colorectal cancer reduces sensitivity to oxidative stress and promotes site-specific metastasis by stimulating glutathione synthesis
    1
    1. scibot 01 Dec 2022
      Addgene #12260

      DOI: 10.1016/j.celrep.2022.111728

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    sciencedirect.com/science/article/pii/S2211124722016060
  5. www.sciencedirect.com www.sciencedirect.com
    SETD1A regulates transcriptional pause release of heme biosynthesis genes in leukemia
    1
    1. scibot 01 Dec 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.111727

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    sciencedirect.com/science/article/pii/S2211124722016059
  6. Nov 2022
  7. www.nature.com www.nature.com
    Microscopy-based phenotypic profiling of infection by Staphylococcus aureus clinical isolates reveals intracellular lifestyle as a prevalent feature
    1
    1. scibot 24 Nov 2022
      addgene_12260

      DOI: 10.1038/s41467-022-34790-9

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    nature.com/articles/s41467-022-34790-9
  8. www.sciencedirect.com www.sciencedirect.com
    Dynamic quality control machinery that operates across compartmental borders mediates the degradation of mammalian nuclear membrane proteins
    1
    1. scibot 24 Nov 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.111675

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    sciencedirect.com/science/article/pii/S2211124722015492
  9. www.sciencedirect.com www.sciencedirect.com
    Autophagy promotes cell survival by maintaining NAD levels
    1
    1. scibot 22 Nov 2022
      12260

      DOI: 10.1016/j.devcel.2022.10.008

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    sciencedirect.com/science/article/pii/S1534580722007602
  10. 52.53.155.43 52.53.155.43
    Nuclear envelope protein LBR protects the genome from chromosomal instability and tumorigenesis
    1
    1. scibot 22 Nov 2022
      plasmid_12260

      DOI: 10.1093/hmg/ddac235

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    52.53.155.43/cc79e40c92dade70c5729b9199717becabfd0bfe/ddac235-html.html
  11. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Alternative splicing downstream of EMT enhances phenotypic plasticity and malignant behavior in colon cancer
    1
    1. scibot 22 Nov 2022
      Addgene_12260

      DOI: 10.7554/eLife.82006

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    ncbi.nlm.nih.gov/pmc/articles/PMC9674345/
  12. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Bcl-xL inhibition radiosensitizes PIK3CA/PTEN wild-type triple negative breast cancers with low Mcl-1 expression
    1
    1. scibot 19 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1158/2767-9764.crc-22-0024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648413/
  13. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Na+/H+-exchanger 1 enhances antitumor activity of engineered NK-92 natural killer cells
    1
    1. scibot 19 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1158/2767-9764.crc-22-0270

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    ncbi.nlm.nih.gov/pmc/articles/PMC9648415/
  14. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    GPI-Anchored Ligand-BioID2-Tagging System Identifies Galectin-1 Mediating Zika Virus Entry
    1
    1. scibot 19 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2022.105481

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    ncbi.nlm.nih.gov/pmc/articles/PMC9668739/
  15. www.sciencedirect.com www.sciencedirect.com
    POLθ processes ssDNA gaps and promotes replication fork progression in BRCA1-deficient cells
    1
    1. scibot 18 Nov 2022
      Plasmid_12260

      DOI: 10.1016/j.celrep.2022.111716

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    sciencedirect.com/science/article/pii/S2211124722015947
  16. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Reciprocal effects of mTOR inhibitors on pro-survival proteins dictate therapeutic responses in tuberous sclerosis complex
    1
    1. scibot 18 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.isci.2022.105458

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    ncbi.nlm.nih.gov/pmc/articles/PMC9663903/
  17. www.pnas.org www.pnas.org
    Tetraspanin-5–mediated MHC class I clustering is required for optimal CD8 T cell activation
    1
    1. scibot 17 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1073/pnas.2122188119

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    pnas.org/doi/abs/10.1073/pnas.2122188119
  18. www.sciencedirect.com www.sciencedirect.com
    Re-purposing the pro-senescence properties of doxorubicin to introduce immunotherapy in breast cancer brain metastasis
    1
    1. scibot 16 Nov 2022
      12260

      DOI: 10.1016/j.xcrm.2022.100821

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    sciencedirect.com/science/article/pii/S2666379122003809
  19. www.sciencedirect.com www.sciencedirect.com
    The adhesion G-protein-coupled receptor Gpr116 is essential to maintain the skeletal muscle stem cell pool
    1
    1. scibot 16 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111645

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    sciencedirect.com/science/article/pii/S2211124722015169
  20. www.sciencedirect.com www.sciencedirect.com
    Genome-scale CRISPR screening in a single mouse liver
    1
    1. scibot 16 Nov 2022
      plasmid_12260

      DOI: 10.1016/j.xgen.2022.100217

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    sciencedirect.com/science/article/pii/S2666979X22001707
  21. www.sciencedirect.com www.sciencedirect.com
    Cancer-selective metabolic vulnerabilities in MYC-amplified medulloblastoma
    1
    1. scibot 11 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.10.009

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    sciencedirect.com/science/article/pii/S1535610822005001
  22. www.sciencedirect.com www.sciencedirect.com
    MsrB1-regulated GAPDH oxidation plays programmatic roles in shaping metabolic and inflammatory signatures during macrophage activation
    1
    1. scibot 10 Nov 2022
      12260

      DOI: 10.1016/j.celrep.2022.111598

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    sciencedirect.com/science/article/pii/S2211124722014632
  23. www.sciencedirect.com www.sciencedirect.com
    Loss of neuronal Tet2 enhances hippocampal-dependent cognitive function
    1
    1. scibot 10 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111612

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    sciencedirect.com/science/article/pii/S2211124722014814
  24. www.sciencedirect.com www.sciencedirect.com
    Bortezomib inhibits ZIKV/DENV by interfering with viral polyprotein cleavage via the ERAD pathway
    1
    1. scibot 09 Nov 2022
      Plasmid_12260

      DOI: 10.1016/j.chembiol.2022.10.003

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    sciencedirect.com/science/article/pii/S2451945622003579
  25. rupress.org rupress.org
    Inherited human ITK deficiency impairs IFN-γ immunity and underlies tuberculosis
    1
    1. scibot 08 Nov 2022
      plasmid_12260

      DOI: 10.1084/jem.20220484

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    rupress.org/jem/article/220/1/e20220484/213662/Inherited-human-ITK-deficiency-impairs-IFN
  26. www.sciencedirect.com www.sciencedirect.com
    Dissecting the genetic and microenvironmental factors of gastric tumorigenesis in mice
    1
    1. scibot 05 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111482

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    sciencedirect.com/science/article/pii/S2211124722013328
  27. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Identification and differential usage of a host metalloproteinase entry pathway by SARS-CoV-2 Delta and Omicron
    2
    1. scibot 04 Nov 2022
      Addgene #12260

      DOI: 10.1016/j.isci.2022.105316

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    2. scibot 04 Nov 2022
      Addgene_12260

      DOI: 10.1016/j.isci.2022.105316

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    ncbi.nlm.nih.gov/pmc/articles/PMC9549715/
  28. www.sciencedirect.com www.sciencedirect.com
    Selective advantage of epigenetically disrupted cancer cells via phenotypic inertia
    1
    1. scibot 04 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.10.002

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    sciencedirect.com/science/article/pii/S1535610822004937
  29. www.sciencedirect.com www.sciencedirect.com
    Uncovering the emergence of HSCs in the human fetal bone marrow by single-cell RNA-seq analysis
    1
    1. scibot 04 Nov 2022
      plasmid_12

      DOI: 10.1016/j.stem.2022.10.005

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    sciencedirect.com/science/article/pii/S1934590922004234
  30. www.sciencedirect.com www.sciencedirect.com
    Multiphase coalescence mediates Hippo pathway activation
    1
    1. scibot 03 Nov 2022
      12260

      DOI: 10.1016/j.cell.2022.09.036

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    sciencedirect.com/science/article/pii/S0092867422012557
  31. www.sciencedirect.com www.sciencedirect.com
    Crystal structure of the CDK11 kinase domain bound to the small-molecule inhibitor OTS964
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.str.2022.10.003

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    sciencedirect.com/science/article/pii/S0969212622003926
  32. www.sciencedirect.com www.sciencedirect.com
    Reversal of mitochondrial malate dehydrogenase 2 enables anaplerosis via redox rescue in respiration-deficient cells
    1
    1. scibot 03 Nov 2022
      plasmid_12260

      DOI: 10.1016/j.molcel.2022.10.005

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    sciencedirect.com/science/article/pii/S1097276522009625
  33. www.nature.com www.nature.com
    HIF1α-AS1 is a DNA:DNA:RNA triplex-forming lncRNA interacting with the HUSH complex
    1
    1. scibot 03 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41467-022-34252-2

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    nature.com/articles/s41467-022-34252-2
  34. www.nature.com www.nature.com
    HIV-1 Rev-RRE functional activity in primary isolates is highly dependent on minimal context-dependent changes in Rev
    1
    1. scibot 02 Nov 2022
      plasmid_12260

      DOI: 10.1038/s41598-022-21714-2

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    nature.com/articles/s41598-022-21714-2
  35. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Nucleoplasmic lamin C rapidly accumulates at sites of nuclear envelope rupture with BAF and cGAS
    1
    1. scibot 02 Nov 2022
      RRID:Addgene_12260

      DOI: 10.1083/jcb.202201024

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    ncbi.nlm.nih.gov/pmc/articles/PMC9617480/
  36. Oct 2022
  37. aacrjournals.org aacrjournals.org
    CircIPO7 Promotes Nasopharyngeal Carcinoma Metastasis and Cisplatin Chemoresistance by Facilitating YBX1 Nuclear Localization
    1
    1. scibot 27 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1158/1078-0432.CCR-22-0991

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    aacrjournals.org/clincancerres/article/28/20/4521/709577/CircIPO7-Promotes-Nasopharyngeal-Carcinoma
  38. www.sciencedirect.com www.sciencedirect.com
    m6A modification confers thermal vulnerability to HPV E7 oncotranscripts via reverse regulation of its reader protein IGF2BP1 upon heat stress
    1
    1. scibot 26 Oct 2022
      12260

      DOI: 10.1016/j.celrep.2022.111546

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    sciencedirect.com/science/article/pii/S2211124722014024
  39. www.sciencedirect.com www.sciencedirect.com
    OTUB2 exerts tumor-suppressive roles via STAT1-mediated CALML3 activation and increased phosphatidylserine synthesis
    1
    1. scibot 26 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.celrep.2022.111561

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    sciencedirect.com/science/article/pii/S221112472201422X
  40. www.sciencedirect.com www.sciencedirect.com
    Circadian lncRNA ADIRF-AS1 binds PBAF and regulates renal clear cell tumorigenesis
    1
    1. scibot 20 Oct 2022
      plasmid_12260

      DOI: 10.1016/j.celrep.2022.111514

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    sciencedirect.com/science/article/pii/S221112472201364X
  41. link.springer.com link.springer.com
    HERC2 deficiency activates C-RAF/MKK3/p38 signalling pathway altering the cellular response to oxidative stress
    1
    1. scibot 15 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1007/s00018-022-04586-7

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    link.springer.com/article/10.1007/s00018-022-04586-7
  42. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BCOR and BCORL1 Mutations Drive Epigenetic Reprogramming and Oncogenic Signaling by Unlinking PRC1.1 from Target Genes
    1
    1. scibot 12 Oct 2022
      Addgene_12260

      DOI: 10.1158/2643-3230.BCD-21-0115

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    ncbi.nlm.nih.gov/pmc/articles/PMC9414116/
  43. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Fast generation of forebrain oligodendrocyte spheroids from human embryonic stem cells by transcription factors
    1
    1. scibot 12 Oct 2022
      Addgene_12260

      DOI: 10.1016/j.isci.2022.105172

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    ncbi.nlm.nih.gov/pmc/articles/PMC9547302/
  44. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    POP1 inhibits MSU-induced inflammasome activation and ameliorates gout
    1
    1. scibot 12 Oct 2022
      plasmid_12260

      DOI: 10.3389/fimmu.2022.912069

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    ncbi.nlm.nih.gov/pmc/articles/PMC9550078/
  45. www.nature.com www.nature.com
    Systematic discovery of recombinases for efficient integration of large DNA sequences into the human genome
    1
    1. scibot 11 Oct 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41587-022-01494-w

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    nature.com/articles/s41587-022-01494-w
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    The primordial differentiation of tumor-specific memory CD8+ T cells as bona fide responders to PD-1/PD-L1 blockade in draining lymph nodes
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  47. www.nature.com www.nature.com
    Enzyme-free targeted DNA demethylation using CRISPR–dCas9-based steric hindrance to identify DNA methylation marks causal to altered gene expression
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    Histone methylation antagonism drives tumor immune evasion in squamous cell carcinomas
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    Expression of vimentin alters cell mechanics, cell-cell adhesion, and gene expression profiles suggesting the induction of a hybrid EMT in human mammary epithelial cells
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  50. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Induced retinal pigment epithelial cells with anti-epithelial-to-mesenchymal transition ability delay retinal degeneration
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  51. Sep 2022
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    Human immunoglobulin repertoire analysis guides design of vaccine priming immunogens targeting HIV V2-apex broadly neutralizing antibody precursors
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    Opto-katanin, an optogenetic tool for localized, microtubule disassembly
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    A feedback loop between lamellipodial extension and HGF-ERK signaling specifies leader cells during collective cell migration
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    The lncRNA ALPHA specifically targets chikungunya virus to control infection
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    A screening-compatible live cell fluorescence resonance energy transfer-based assay for modulation of Rho GTPase activity
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  57. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Effects of stem cells and amniotic fluid on uterus and ovaries in a rat model of abdominal adhesions: a controlled study
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  58. journals.biologists.com journals.biologists.com
    TGFBR3 supports anoikis through suppressing ATF4 signaling
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    GABP couples oncogene signaling to telomere regulation in TERT promoter mutant cancer
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    Meteorin links the bone marrow hypoxic state to hematopoietic stem/progenitor cell mobilization
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    Original research: Extracellular Vesicles from Pancreatic Cancer Stem Cells Lead an Intratumor Communication Network (EVNet) to fuel tumour progression
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    Renal oncometabolite L-2-hydroxyglutarate imposes a block in kidney tubulogenesis: Evidence for an epigenetic basis for the L-2HG-induced impairment of differentiation
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    Snail maintains the stem/progenitor state of skin epithelial cells and carcinomas through the autocrine effect of matricellular protein Mindin
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  64. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    ACE2-containing defensosomes serve as decoys to inhibit SARS-CoV-2 infection
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    CRISPR-Cas9 screen in human embryonic stem cells to identify genes required for neural differentiation
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    Scalable CRISPR-Cas9 chemical genetic screens in non-transformed human cells
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    SerpinB3 drives cancer stem cell survival in glioblastoma
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  68. onlinelibrary.wiley.com onlinelibrary.wiley.com
    Inhibition of insulin-like growth factor-1 receptor enhances eribulin-induced DNA damage in colorectal cancer
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  69. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Development and Characterization of a Luciferase Labeled, Syngeneic Murine Model of Ovarian Cancer
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    NCOA4-mediated ferritinophagy is a pancreatic cancer dependency via maintenance of iron bioavailability for iron-sulfur cluster proteins
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    Runx2 regulates chromatin accessibility to direct the osteoblast program at neonatal stages
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  72. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Human coronaviruses disassemble processing bodies
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  73. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Mutant-IDH inhibits Interferon-TET2 signaling to promote immunoevasion and tumor maintenance in cholangiocarcinoma
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  74. aacrjournals.org aacrjournals.org
    Na+/H+-exchanger 1 Enhances Antitumor Activity of Engineered NK-92 Natural Killer Cells
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    TREM2 Promotes Immune Evasion by Mycobacterium tuberculosis in Human Macrophages
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    Membrane-Tethered Mucin 1 Is Stimulated by Interferon and Virus Infection in Multiple Cell Types and Inhibits Influenza A Virus Infection in Human Airway Epithelium
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    Inhibition of HIV-1 replication using the CRISPR/cas9-no NLS system as a prophylactic strategy
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    Transmembrane protein KIRREL1 regulates Hippo signaling via a feedback loop and represents a therapeutic target in YAP/TAZ-active cancers
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    RBM45 is an m6A-binding protein that affects neuronal differentiation and the splicing of a subset of mRNAs
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    SMNDC1 links chromatin remodeling and splicing to regulate pancreatic hormone expression
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    DEPDC5-dependent mTORC1 signaling mechanisms are critical for the anti-seizure effects of acute fasting
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    S146L in MYC is a context-dependent activating substitution in cancer development
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    Functional map of SARS-CoV-2 3CL protease reveals tolerant and immutable sites
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  85. 52.53.155.43 52.53.155.43
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  86. 52.53.155.43 52.53.155.43
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  87. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Decoding Functional High-Density Lipoprotein Particle Surfaceome Interactions
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    Krüppel-like factor 5 rewires NANOG regulatory network to activate human naive pluripotency specific LTR7Ys and promote naive pluripotency
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    RBM47 is a Critical Regulator of Mouse Embryonic Stem Cell Differentiation
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    CRISPRi-mediated knock-down of PRDM1/BLIMP1 programs central memory differentiation in ex vivo-expanded human T cells
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  92. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Comprehensive analysis of mycobacterium tuberculosis antigen-specific CD4+ T cell responses restricted by single HLA class II allotype in an individual
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    A druggable addiction to de novo pyrimidine biosynthesis in diffuse midline glioma
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    Stromal remodeling regulates dendritic cell abundance and activity in the tumor microenvironment
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    Epigenetic reader SP140 loss of function drives Crohn’s disease due to uncontrolled macrophage topoisomerases
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    Endocytic membrane repair by ESCRT-III controls antigen export to the cytosol during antigen cross-presentation
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  97. aacrjournals.org aacrjournals.org
    Proteomic mapping and targeting of mitotic pericentriolar material in tumors bearing centrosome amplification
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  98. journals.plos.org journals.plos.org
    Genome-wide screening identified SEC61A1 as an essential factor for mycolactone-dependent apoptosis in human premonocytic THP-1 cells
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  99. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Expanded ACE2 dependencies of diverse SARS-like coronavirus receptor binding domains
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    Protocol for the generation of HIV-1 genomic RNA with altered levels of N6-methyladenosine
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    Protein Scaffold‐Based Multimerization of Soluble ACE2 Efficiently Blocks SARS‐CoV‐2 Infection In Vitro and In Vivo
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    BCL10 mutations define distinct dependencies guiding precision therapy for DLBCL
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  104. rupress.org rupress.org
    Dissecting protein tyrosine phosphatase signaling by engineered chemogenetic control of its activity
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    METTL14-dependent m6A modification controls iNKT cell development and function
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    Protocol for genome-wide CRISPR knockout screens of bacterial cytotoxins in HeLa cells
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    The endoplasmic reticulum membrane complex promotes proteostasis of GABAA receptors
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  108. Jul 2022
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    HDAC2- and EZH2-Mediated Histone Modifications Induce PDK1 Expression through miR-148a Downregulation in Breast Cancer Progression and Adriamycin Resistance
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    Mapping subcellular localizations of unannotated microproteins and alternative proteins with MicroID
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  112. 52.53.155.43 52.53.155.43
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  113. aacrjournals.org aacrjournals.org
    Bcl-xL Inhibition Radiosensitizes PIK3CA/PTEN Wild-type Triple-negative Breast Cancers with Low Mcl-1 Expression
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  114. 52.53.155.43 52.53.155.43
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  115. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Self-assembly of pericentriolar material in interphase cells lacking centrioles
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  116. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
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    A RET::GRB2 fusion in pheochromocytoma defies the classic paradigm of RET oncogenic fusions
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    Resolving SARS-CoV-2 CD4+ T cell specificity via reverse epitope discovery
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    Mislocalization of protein kinase A drives pathology in Cushing’s syndrome
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  120. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Targeting the transcriptional activity of STAT3 by a novel fusion protein
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  121. www.sciencedirect.com www.sciencedirect.com
    EPH receptor tyrosine kinases phosphorylate the PAR-3 scaffold protein to modulate downstream signaling networks
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  122. Jun 2022
  123. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Transcriptional reprogramming differentiates active from inactive ESR1 fusions in endocrine therapy-refractory metastatic breast cancer
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  124. 52.53.155.43 52.53.155.43
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  125. 52.53.155.43 52.53.155.43
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  126. www.embopress.org www.embopress.org
    Engagement of TRAIL triggers degranulation and IFNγ production in human natural killer cells
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    Methionine oxidation activates pyruvate kinase M2 to promote pancreatic cancer metastasis
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    Epigenomic analysis reveals a dynamic and context-specific macrophage enhancer landscape associated with innate immune activation and tolerance
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    Lenalidomide bypasses CD28 co-stimulation to reinstate PD-1 immunotherapy by activating Notch signaling
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    Targeting EP2 receptor with multifaceted mechanisms for high-risk neuroblastoma
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    Endogenous spacing enables co-processing of microRNAs and efficient combinatorial RNAi
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    Supramolecular assembly of GSK3α as a cellular response to amino acid starvation
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  133. www.sciencedirect.com www.sciencedirect.com
    Analysis of estrogen-regulated enhancer RNAs identifies a functional motif required for enhancer assembly and gene expression
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    Immunization with a self-assembling nanoparticle vaccine displaying EBV gH/gL protects humanized mice against lethal viral challenge
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  135. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Acquisition of cellular properties during alveolar formation requires differential activity and distribution of mitochondria
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  136. www.nature.com www.nature.com
    RNF43 G659fs is an oncogenic colorectal cancer mutation and sensitizes tumor cells to PI3K/mTOR inhibition
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  137. www.sciencedirect.com www.sciencedirect.com
    RNF31 inhibition sensitizes tumors to bystander killing by innate and adaptive immune cells
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    Granger-causal inference of the lamellipodial actin regulator hierarchy by live cell imaging without perturbation
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    Drug screen in iPSC-Neurons identifies nucleoside analogs as inhibitors of (G4C2)n expression in C9orf72 ALS/FTD
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    Itaconate is a lysosomal inducer that promotes antibacterial innate immunity
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  141. link.springer.com link.springer.com
    Potential therapeutic targets discovery by transcriptome analysis of an in vitro human gastric signet ring carcinoma model
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  142. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    HIF1α/HIF2α induces glioma cell dedifferentiation into cancer stem cells through Sox2 under hypoxic conditions
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  143. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    The SETDB1–TRIM28 complex suppresses antitumor immunity
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  144. www.sciencedirect.com www.sciencedirect.com
    YAP1 activation is associated with the progression and response to immunotherapy of non-muscle invasive bladder cancer
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  145. www.sciencedirect.com www.sciencedirect.com
    A pro-metastatic tRNA fragment drives Nucleolin oligomerization and stabilization of its bound metabolic mRNAs
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  146. May 2022
  147. link.springer.com link.springer.com
    Endocytic trafficking of GAS6–AXL complexes is associated with sustained AKT activation
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  148. www.sciencedirect.com www.sciencedirect.com
    DDX41 is required for cGAS-STING activation against DNA virus infection
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    Delineating the mechanism of anti-Lassa virus GPC-A neutralizing antibodies
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  150. www.sciencedirect.com www.sciencedirect.com
    Heterochronic parabiosis induces stem cell revitalization and systemic rejuvenation across aged tissues
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  151. www.sciencedirect.com www.sciencedirect.com
    Large-scale chromatin reorganization reactivates placenta-specific genes that drive cellular aging
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  152. www.sciencedirect.com www.sciencedirect.com
    F-box protein FBXO41 suppresses breast cancer growth by inducing autophagic cell death through facilitating proteasomal degradation of oncogene SKP2
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  153. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Leveraging Allele-Specific Expression for Therapeutic Response Gene Discovery in Glioblastoma
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      RRID:Addgene_12260

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  154. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    C/EBPδ-induced epigenetic changes control the dynamic gene transcription of S100a8 and S100a9
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      DOI: 10.7554/eLife.75594

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  155. www.sciencedirect.com www.sciencedirect.com
    Free fatty acid receptor 4 deletion attenuates colitis by modulating Treg Cells via ZBED6-IL33 pathway
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  156. www.sciencedirect.com www.sciencedirect.com
    c-JUN inhibits mTORC2 and glucose uptake to promote self-renewal and obesity
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  157. www.sciencedirect.com www.sciencedirect.com
    Glycyrrhetinic acid restricts mitochondrial energy metabolism by targeting SHMT2
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  158. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Paracrine signalling between intestinal epithelial and tumour cells induces a regenerative programme
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  159. www.nature.com www.nature.com
    Purine nucleotide depletion prompts cell migration by stimulating the serine synthesis pathway
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  160. www.sciencedirect.com www.sciencedirect.com
    MiR-25 blunts autophagy and promotes the survival of Mycobacterium tuberculosis by regulating NPC1
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  161. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A diabetic milieu increases ACE2 expression and cellular susceptibility to SARS-CoV-2 infections in human kidney organoids and patient cells
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  162. aacrjournals.org aacrjournals.org
    Melanoma-secreted Amyloid Beta Suppresses Neuroinflammation and Promotes Brain Metastasis
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      DOI: 10.1158/2159-8290.CD-21-1006

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  163. www.sciencedirect.com www.sciencedirect.com
    Loss-of-function variants in the schizophrenia risk gene SETD1A alter neuronal network activity in human neurons through the cAMP/PKA pathway
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  164. www.sciencedirect.com www.sciencedirect.com
    NSD1 mediates antagonism between SWI/SNF and polycomb complexes and is required for transcriptional activation upon EZH2 inhibition
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  165. www.sciencedirect.com www.sciencedirect.com
    Lymph node colonization induces tumor-immune tolerance to promote distant metastasis
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  166. www.nature.com www.nature.com
    Patient-derived and mouse endo-ectocervical organoid generation, genetic manipulation and applications to model infection
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  167. www.sciencedirect.com www.sciencedirect.com
    Interactomic analysis reveals a homeostatic role for the HIV restriction factor TRIM5α in mitophagy
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    SETD4-mediated KU70 methylation suppresses apoptosis
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  169. www.sciencedirect.com www.sciencedirect.com
    The lactate-NAD+ axis activates cancer-associated fibroblasts by downregulating p62
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  170. www.sciencedirect.com www.sciencedirect.com
    The gut microbiota prime systemic antiviral immunity via the cGAS-STING-IFN-I axis
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      Addgene: #12260

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  171. aacrjournals.org aacrjournals.org
    Repurposing Itraconazole and Hydroxychloroquine to Target Lysosomal Homeostasis in Epithelial Ovarian Cancer
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  172. www.science.org www.science.org
    Targeted epigenomic editing ameliorates adult anxiety and excessive drinking after adolescent alcohol exposure
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  173. www.nature.com www.nature.com
    The AMPK-related kinase NUAK2 suppresses glutathione peroxidase 4 expression and promotes ferroptotic cell death in breast cancer cells
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      Plasmid_12260

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  174. www.sciencedirect.com www.sciencedirect.com
    Cannabinoid receptor 1 antagonist genistein attenuates marijuana-induced vascular inflammation
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      Addgene_12260

      DOI: 10.1016/j.cell.2022.04.005

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    sciencedirect.com/science/article/pii/S0092867422004433
  175. www.nature.com www.nature.com
    Transcription Factor 4 loss-of-function is associated with deficits in progenitor proliferation and cortical neuron content
    1
    1. scibot 03 May 2022
      Addgene_12260

      DOI: 10.1038/s41467-022-29942-w

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    nature.com/articles/s41467-022-29942-w
  176. Apr 2022
  177. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Hypoxic, glycolytic metabolism is a vulnerability of B-acute lymphoblastic leukemia-initiating cells
    1
    1. scibot 27 Apr 2022
      Addgene12260

      DOI: 10.1016/j.celrep.2022.110752

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    ncbi.nlm.nih.gov/pmc/articles/PMC9099058/
  178. www.nature.com www.nature.com
    Identifying a confused cell identity for esophageal squamous cell carcinoma
    1
    1. scibot 23 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1038/s41392-022-00946-8

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    nature.com/articles/s41392-022-00946-8
  179. aacrjournals.org aacrjournals.org
    CDK2 Inhibition Enhances Antitumor Immunity by Increasing IFN Response to Endogenous Retroviruses
    1
    1. scibot 22 Apr 2022
      Addgene plasmid #12260

      DOI: 10.1158/2326-6066.CIR-21-0806

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    aacrjournals.org/cancerimmunolres/article/10/4/525/689540/CDK2-Inhibition-Enhances-Antitumor-Immunity-by
  180. www.sciencedirect.com www.sciencedirect.com
    Establishing transgenic murine esophageal organoids
    1
    1. scibot 22 Apr 2022
      AddgeneCat# 12260

      DOI: 10.1016/j.xpro.2022.101317

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    sciencedirect.com/science/article/pii/S2666166722001976
  181. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    BRAF Inhibitor Resistance Confers Increased Sensitivity to Mitotic Inhibitors
    1
    1. scibot 22 Apr 2022
      plasmid_12260

      DOI: 10.3389/fonc.2022.766794

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    ncbi.nlm.nih.gov/pmc/articles/PMC9015667/
  182. www.sciencedirect.com www.sciencedirect.com
    In vitro and in vivo assay of the ER lipid scramblase TMEM41B
    1
    1. scibot 21 Apr 2022
      Addgene Cat# 12260

      DOI: 10.1016/j.xpro.2022.101333

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    sciencedirect.com/science/article/pii/S2666166722002131
  183. www.sciencedirect.com www.sciencedirect.com
    Multilayered omics reveal sex- and depot-dependent adipose progenitor cell heterogeneity
    1
    1. scibot 21 Apr 2022
      AddgeneCat# 12260

      DOI: 10.1016/j.cmet.2022.03.012

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    sciencedirect.com/science/article/pii/S1550413122001267
  184. www.sciencedirect.com www.sciencedirect.com
    Mitochondrial dynamics regulate genome stability via control of caspase-dependent DNA damage
    1
    1. scibot 21 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.devcel.2022.03.019

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    sciencedirect.com/science/article/pii/S1534580722002295
  185. www.sciencedirect.com www.sciencedirect.com
    CDYL1-dependent decrease in lysine crotonylation at DNA double-strand break sites functionally uncouples transcriptional silencing and repair
    1
    1. scibot 21 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.molcel.2022.03.031

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    sciencedirect.com/science/article/pii/S1097276522002696
  186. www.sciencedirect.com www.sciencedirect.com
    Augmenting NK cell-based immunotherapy by targeting mitochondrial apoptosis
    1
    1. scibot 21 Apr 2022
      Plasmid_12260

      DOI: 10.1016/j.cell.2022.03.030

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    sciencedirect.com/science/article/pii/S0092867422003403
  187. www.sciencedirect.com www.sciencedirect.com
    A presynaptic phosphosignaling hub for lasting homeostatic plasticity
    1
    1. scibot 20 Apr 2022
      Addgene12260

      DOI: 10.1016/j.celrep.2022.110696

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    sciencedirect.com/science/article/pii/S2211124722004545
  188. www.sciencedirect.com www.sciencedirect.com
    Mitotic Spindle Positioning (MISP) is an actin bundler that selectively stabilizes the rootlets of epithelial microvilli
    1
    1. scibot 20 Apr 2022
      AddgeneCat# 12260

      DOI: 10.1016/j.celrep.2022.110692

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    sciencedirect.com/science/article/pii/S2211124722004508
  189. www.sciencedirect.com www.sciencedirect.com
    Microglia/macrophage-derived human CCL18 promotes glioma progression via CCR8-ACP5 axis analyzed in humanized slice model
    1
    1. scibot 15 Apr 2022
      AddgeneCat#12260

      DOI: 10.1016/j.celrep.2022.110670

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    sciencedirect.com/science/article/pii/S2211124722004223
  190. www.sciencedirect.com www.sciencedirect.com
    Ovarian cancer immunogenicity is governed by a narrow subset of progenitor tissue-resident memory T cells
    2
    1. scibot 15 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.ccell.2022.03.008

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    2. scibot 15 Apr 2022
      RRID: Addgene_12260

      DOI: 10.1016/j.ccell.2022.03.008

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    sciencedirect.com/science/article/pii/S1535610822001234
  191. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Imprinted SARS-CoV-2-specific memory lymphocytes define hybrid immunity
    1
    1. scibot 14 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.cell.2022.03.018

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    ncbi.nlm.nih.gov/pmc/articles/PMC8926873/
  192. www.sciencedirect.com www.sciencedirect.com
    Nuclear microRNAs release paused Pol II via the DDX21-CDK9 complex
    1
    1. scibot 14 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.110673

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    sciencedirect.com/science/article/pii/S2211124722004259
  193. www.sciencedirect.com www.sciencedirect.com
    Rapid establishment of human colonic organoid knockout lines
    1
    1. scibot 14 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.xpro.2022.101308

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    sciencedirect.com/science/article/pii/S2666166722001885
  194. www.sciencedirect.com www.sciencedirect.com
    Brown adipose tissue involution associated with progressive restriction in progenitor competence
    1
    1. scibot 14 Apr 2022
      Addgene_12260

      DOI: 10.1016/j.celrep.2022.110575

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    sciencedirect.com/science/article/pii/S2211124722003199
  195. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    Protease inhibitor Camostat Mesyalte blocks wild type SARS-CoV-2 and D614G viral entry in human engineered miniature lungs
    1
    1. scibot 14 Apr 2022
      RRID:Addgene_12

      DOI: 10.1016/j.biomaterials.2022.121509

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    ncbi.nlm.nih.gov/pmc/articles/PMC8999341/
  196. www.sciencedirect.com www.sciencedirect.com
    Neoantigen-specific CD4+ T cells in human melanoma have diverse differentiation states and correlate with CD8+ T cell, macrophage, and B cell function
    1
    1. scibot 13 Apr 2022
      Plasmid_12260

      DOI: 10.1016/j.ccell.2022.03.006

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    sciencedirect.com/science/article/pii/S1535610822001210
  197. www.sciencedirect.com www.sciencedirect.com
    The interferon-stimulated gene RIPK1 regulates cancer cell intrinsic and extrinsic resistance to immune checkpoint blockade
    1
    1. scibot 13 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.immuni.2022.03.007

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    sciencedirect.com/science/article/pii/S1074761322001303
  198. www.ncbi.nlm.nih.gov www.ncbi.nlm.nih.gov
    A Single Transcript Knockdown-Replacement Strategy Employing 5’ UTR Secondary Structures to Precisely Titrate Rescue Protein Translation
    1
    1. scibot 13 Apr 2022
      RRID:Addgene_12260

      DOI: 10.3389/fgeed.2022.803375

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    ncbi.nlm.nih.gov/pmc/articles/PMC8995503/
  199. www.sciencedirect.com www.sciencedirect.com
    Altered BAF occupancy and transcription factor dynamics in PBAF-deficient melanoma
    1
    1. scibot 07 Apr 2022
      AddgeneCat# 12260

      DOI: 10.1016/j.celrep.2022.110637

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    sciencedirect.com/science/article/pii/S2211124722003898
  200. www.sciencedirect.com www.sciencedirect.com
    Filamentous GLS1 promotes ROS-induced apoptosis upon glutamine deprivation via insufficient asparagine synthesis
    1
    1. scibot 07 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1016/j.molcel.2022.03.016

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    sciencedirect.com/science/article/pii/S1097276522002544
  201. aacrjournals.org aacrjournals.org
    GFI1 cooperates with IKZF1/IKAROS to activate gene expression in T-cell acute lymphoblastic leukemia
    1
    1. scibot 05 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1158/1541-7786.MCR-21-0352

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    aacrjournals.org/mcr/article/20/4/501/682307/GFI1-Cooperates-with-IKZF1-IKAROS-to-Activate-Gene
  202. bpspubs.onlinelibrary.wiley.com bpspubs.onlinelibrary.wiley.com
    BPS Publications
    1
    1. scibot 05 Apr 2022
      RRID:Addgene_12260

      DOI: 10.1111/bph.15763

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    bpspubs.onlinelibrary.wiley.com/doi/10.1111/bph.15763